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person · Reporting owner

CROOKE STANLEY T

Disclosed activity across 2 companies

Tapewire entity
143377
SEC CIK
0000897667

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Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
AKCEA THERAPEUTICS, INC.AKCA · Entity 145982DirectorJuly 13, 2017July 13, 2017
IONIS PHARMACEUTICALS INCIONS · Entity 1182Director · Exec Chairman of the BoardJanuary 26, 2021January 29, 2021

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

AKCEA THERAPEUTICS, INC.

Report date July 13, 2017 · Filed July 13, 2017

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
No securities are beneficially owned.SEC Table I · non-derivativeDirect0 Reported balance Holding disclosure · report date 2017-07-13 · row 1 Holding and transaction disclosures are not merged.
1 source row

Row 1 · Balance 0

IONIS PHARMACEUTICALS INC

Report date January 26, 2021 · Filed January 29, 2021

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect2,021 Reported balance After 2021-01-26 transaction · row 1
1 source row

Row 1 · 2021-01-26 · Sale · Disposed 28,333 · Balance 2,021

F1: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on January 2, 2020.

F2: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $63.00 to $64.00, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (2) of this Form 4.

Common StockSEC Table I · non-derivativeIndirectBy wife3,111 Reported balance Holding disclosure · report date 2021-01-26 · row 2 Holding and transaction disclosures are not merged.
1 source row

Row 2 · Balance 3,111

Common StockSEC Table I · non-derivativeIndirectBy trust494,391 Reported balance Holding disclosure · report date 2021-01-26 · row 3 Holding and transaction disclosures are not merged.
1 source row

Row 3 · Balance 494,391

Filing footnotes · ownership attribution and instrument terms

F1: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on January 2, 2020.

F2: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $63.00 to $64.00, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (2) of this Form 4.

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
January 26, 2021 Filed Jan 29, 2021 00:22 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 28,333 $63.74 $1,805,812.25
Disclosure

SEC source: 0000874015-21-000051 · edgar.xml · nonDerivative · entry 1

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,021

F1 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on January 2, 2020.

F2 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $63.00 to $64.00, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (2) of this Form 4.

Read SEC document
January 22, 2021 Filed Jan 26, 2021 01:24 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 40,000 $61.68 $2,467,000.00
Disclosure

SEC source: 0000874015-21-000047 · edgar.xml · nonDerivative · entry 3

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Indirect · By trust

Disclosed balance after: 494,391

F1 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on January 2, 2020.

F4 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $61.00 to $62.00, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (4) of this Form 4.

Read SEC document
January 21, 2021 Filed Jan 26, 2021 01:24 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 21,042 $61.65 $1,297,239.30
Disclosure

SEC source: 0000874015-21-000047 · edgar.xml · nonDerivative · entry 2

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Indirect · By trust

Disclosed balance after: 534,391

F1 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on January 2, 2020.

F3 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $61.25 to $62.15, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (3) of this Form 4.

Read SEC document
January 21, 2021 Filed Jan 26, 2021 01:24 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 13,958 $60.53 $844,877.74
Disclosure

SEC source: 0000874015-21-000047 · edgar.xml · nonDerivative · entry 1

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Indirect · By trust

Disclosed balance after: 555,433

F1 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on January 2, 2020.

F2 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $60.20 to $61.00, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (2) of this Form 4.

Read SEC document
January 15, 2021 Filed Jan 21, 2021 00:12 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionRestricted Stock Units · Derivative 4,371 $0.00 $0.00
Disclosure

SEC source: 0000874015-21-000045 · edgar.xml · derivative · entry 8

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 7,801

Underlying: Common Stock · 4,371 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_price: Each Restricted Stock Unit represents a contingent right to receive one share of Ionis common stock, or its equivalent cash value.

F5 · derivative.exercise_date: Restricted Stock Units vest in four equal annual installments. Upon vesting, the Restricted Stock Units will be paid out in whole shares of Ionis common stock or cash as may be determined by Ionis.

F5 · derivative.expiration_date: Restricted Stock Units vest in four equal annual installments. Upon vesting, the Restricted Stock Units will be paid out in whole shares of Ionis common stock or cash as may be determined by Ionis.

Read SEC document
January 15, 2021 Filed Jan 21, 2021 00:12 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionRestricted Stock Units · Derivative 47,257 $0.00 $0.00
Disclosure

SEC source: 0000874015-21-000045 · edgar.xml · derivative · entry 7

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 87,885

Underlying: Common Stock · 47,257 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_price: Each Restricted Stock Unit represents a contingent right to receive one share of Ionis common stock, or its equivalent cash value.

F5 · derivative.exercise_date: Restricted Stock Units vest in four equal annual installments. Upon vesting, the Restricted Stock Units will be paid out in whole shares of Ionis common stock or cash as may be determined by Ionis.

F5 · derivative.expiration_date: Restricted Stock Units vest in four equal annual installments. Upon vesting, the Restricted Stock Units will be paid out in whole shares of Ionis common stock or cash as may be determined by Ionis.

Read SEC document
January 15, 2021 Filed Jan 21, 2021 00:12 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 GrantRestricted Stock Units · Derivative 5,333 $0.00 $0.00
Disclosure

SEC source: 0000874015-21-000045 · edgar.xml · derivative · entry 6

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,333

Underlying: Common Stock · 5,333 shares

Expires not disclosed

F3 · derivative.exercise_price: Grant to reporting person of Restricted Stock Units under the Ionis Pharmaceuticals, Inc. Amended and Restated 2011 Equity Incentive Plan.

F4 · derivative.exercise_price: Each Restricted Stock Unit represents a contingent right to receive one share of Ionis common stock, or its equivalent cash value.

F5 · derivative.exercise_date: Restricted Stock Units vest in four equal annual installments. Upon vesting, the Restricted Stock Units will be paid out in whole shares of Ionis common stock or cash as may be determined by Ionis.

F5 · derivative.expiration_date: Restricted Stock Units vest in four equal annual installments. Upon vesting, the Restricted Stock Units will be paid out in whole shares of Ionis common stock or cash as may be determined by Ionis.

Read SEC document
January 15, 2021 Filed Jan 21, 2021 00:12 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Tax withholdingCommon Stock 1,434 $61.28 $87,875.52
Disclosure

SEC source: 0000874015-21-000045 · edgar.xml · nonDerivative · entry 4

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 3,111

F2 · kind: Shares withheld to cover the required tax withholding obligations pursuant to the Ionis Pharmaceuticals, Inc. Amended and Restated 2011 Equity Incentive Plan.

F2 · shares: Shares withheld to cover the required tax withholding obligations pursuant to the Ionis Pharmaceuticals, Inc. Amended and Restated 2011 Equity Incentive Plan.

Read SEC document
January 15, 2021 Filed Jan 21, 2021 00:12 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionCommon Stock 4,371 $0.00 $0.00
Disclosure

SEC source: 0000874015-21-000045 · edgar.xml · nonDerivative · entry 3

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 4,545

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired pursuant to vesting and release of shares in accordance with Restricted Stock Unit awards.

F1 · shares: Acquired pursuant to vesting and release of shares in accordance with Restricted Stock Unit awards.

Read SEC document
January 15, 2021 Filed Jan 21, 2021 00:12 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Tax withholdingCommon Stock 18,924 $61.28 $1,159,662.72
Disclosure

SEC source: 0000874015-21-000045 · edgar.xml · nonDerivative · entry 2

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,354

F2 · kind: Shares withheld to cover the required tax withholding obligations pursuant to the Ionis Pharmaceuticals, Inc. Amended and Restated 2011 Equity Incentive Plan.

F2 · shares: Shares withheld to cover the required tax withholding obligations pursuant to the Ionis Pharmaceuticals, Inc. Amended and Restated 2011 Equity Incentive Plan.

Read SEC document
January 15, 2021 Filed Jan 21, 2021 00:12 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionCommon Stock 47,257 $0.00 $0.00
Disclosure

SEC source: 0000874015-21-000045 · edgar.xml · nonDerivative · entry 1

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 49,278

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired pursuant to vesting and release of shares in accordance with Restricted Stock Unit awards.

F1 · shares: Acquired pursuant to vesting and release of shares in accordance with Restricted Stock Unit awards.

Read SEC document
January 04, 2021 Filed Jan 7, 2021 02:20 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 GrantEmployee Stock Option (right to buy) · Derivative 12,000 $0.00 Strike: $56.78 $0.00
Disclosure

SEC source: 0000874015-21-000017 · edgar.xml · derivative · entry 1

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,000

Underlying: Common Stock · 12,000 shares

Expires 2028-01-03

F1 · derivative.exercise_date: Grant on 01/04/2021 to reporting person of stock options under the Ionis Pharmaceuticals, Inc. Amended and Restated 2011 Equity Incentive Plan. Following this transaction, the option was exercisable as to 0 shares on 01/04/2021. 25% of the shares subject to the option will vest and become exercisable on 01/04/2022. Thereafter, the remaining shares subject to the option will vest and become exercisable in 36 equal monthly installments over the next 3 years.

Read SEC document
December 17, 2020 Filed Dec 18, 2020 00:42 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 1,407 $50.50 $71,053.50
Disclosure

SEC source: 0000874015-20-000172 · edgar.xml · nonDerivative · entry 2

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Indirect · by wife

Disclosed balance after: 174

F3 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person's wife on January 2, 2020.

Read SEC document
December 15, 2020 Filed Dec 18, 2020 00:42 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 39,000 $49.78 $1,941,225.00
Disclosure

SEC source: 0000874015-20-000172 · edgar.xml · nonDerivative · entry 1

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Indirect · by trust

Disclosed balance after: 600,391

F1 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on January 2, 2020.

F2 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $49.50 to $50.00, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (2) of this Form 4.

Read SEC document
December 07, 2020 Filed Dec 10, 2020 01:14 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 6,000 $51.50 $309,000.00
Disclosure

SEC source: 0000874015-20-000170 · edgar.xml · nonDerivative · entry 2

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Indirect · by trust

Disclosed balance after: 639,391

F1 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on January 2, 2020.

Read SEC document
December 07, 2020 Filed Dec 10, 2020 01:14 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 5,000 $51.87 $259,350.50
Disclosure

SEC source: 0000874015-20-000170 · edgar.xml · nonDerivative · entry 1

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Indirect · by trust

Disclosed balance after: 645,391

F1 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on January 2, 2020.

Read SEC document
November 25, 2020 Filed Nov 30, 2020 23:48 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 12,990 $0.00 Strike: $39.87 $0.00
Disclosure

SEC source: 0000874015-20-000158 · edgar.xml · derivative · entry 5

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 0 shares

Expires 2021-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 25, 2020 Filed Nov 30, 2020 23:48 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 12,990 $50.05 $650,149.50
Disclosure

SEC source: 0000874015-20-000158 · edgar.xml · nonDerivative · entry 2

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,021

F2 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on March 13, 2019.

F3 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $49.85 to $50.25, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (3) of this Form 4.

Read SEC document
November 25, 2020 Filed Nov 30, 2020 23:48 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionCommon Stock 12,990 $39.87 $517,911.30
Disclosure

SEC source: 0000874015-20-000158 · edgar.xml · nonDerivative · entry 1

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,011

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: Acquired as a result of exercising a stock option that was scheduled to expire on 1/1/21. The purchase reported on this Form 4 was effected pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on March 13, 2019.

Read SEC document
November 24, 2020 Filed Nov 26, 2020 00:04 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 2,590 $0.00 Strike: $39.87 $0.00
Disclosure

SEC source: 0000874015-20-000152 · edgar.xml · derivative · entry 10

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,990

Underlying: Common Stock · 0 shares

Expires 2021-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 24, 2020 Filed Nov 26, 2020 00:04 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 2,590 $50.83 $131,649.70
Disclosure

SEC source: 0000874015-20-000152 · edgar.xml · nonDerivative · entry 6

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,021

F4 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on March 13, 2019.

F6 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $50.50 to $51.00, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (6) of this Form 4.

Read SEC document
November 24, 2020 Filed Nov 26, 2020 00:04 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionCommon Stock 2,590 $39.87 $103,263.30
Disclosure

SEC source: 0000874015-20-000152 · edgar.xml · nonDerivative · entry 5

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,611

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · shares: Acquired as a result of exercising a stock option that was scheduled to expire on 1/1/21. The purchase reported on this Form 4 was effected pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on March 13, 2019.

Read SEC document
November 23, 2020 Filed Nov 26, 2020 00:04 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 11,600 $0.00 Strike: $39.87 $0.00
Disclosure

SEC source: 0000874015-20-000152 · edgar.xml · derivative · entry 9

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,580

Underlying: Common Stock · 0 shares

Expires 2021-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 23, 2020 Filed Nov 26, 2020 00:04 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 500 $0.00 Strike: $39.87 $0.00
Disclosure

SEC source: 0000874015-20-000152 · edgar.xml · derivative · entry 8

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Indirect · by wife

Disclosed balance after: 0

Underlying: Common Stock · 0 shares

Expires 2021-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 23, 2020 Filed Nov 26, 2020 00:04 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 11,600 $50.11 $581,276.00
Disclosure

SEC source: 0000874015-20-000152 · edgar.xml · nonDerivative · entry 4

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,021

F4 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on March 13, 2019.

F5 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $50.00 to $50.25, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (5) of this Form 4.

Read SEC document
November 23, 2020 Filed Nov 26, 2020 00:04 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionCommon Stock 11,600 $39.87 $462,492.00
Disclosure

SEC source: 0000874015-20-000152 · edgar.xml · nonDerivative · entry 3

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,621

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · shares: Acquired as a result of exercising a stock option that was scheduled to expire on 1/1/21. The purchase reported on this Form 4 was effected pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on March 13, 2019.

Read SEC document
November 23, 2020 Filed Nov 26, 2020 00:04 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 500 $50.00 $25,000.00
Disclosure

SEC source: 0000874015-20-000152 · edgar.xml · nonDerivative · entry 2

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Indirect · by wife

Disclosed balance after: 1,581

F2 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person's wife on March 13, 2019.

Read SEC document
November 23, 2020 Filed Nov 26, 2020 00:04 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionCommon Stock 500 $39.87 $19,935.00
Disclosure

SEC source: 0000874015-20-000152 · edgar.xml · nonDerivative · entry 1

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Indirect · by wife

Disclosed balance after: 2,081

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: Acquired as a result of exercising a stock option that was scheduled to expire on 1/1/21. The purchase reported on this Form 4 was effected pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person's wife on March 13, 2019.

Read SEC document
November 19, 2020 Filed Jan 7, 2021 02:17 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 GiftCommon Stock 31,000 $0.00 $0.00
Disclosure

SEC source: 0000874015-21-000015 · edgar.xml · nonDerivative · entry 1

CROOKE STANLEY T · CIK 0000897667 · Director · Executive Chairman of Board

10b5-1 filing: Not disclosed

Ownership: Indirect · By trust

Disclosed balance after: 569,391

F1 · kind: Represents a bona fide gift to a charitable organization.

Read SEC document
September 22, 2020 Filed Sep 23, 2020 22:44 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 50,000 $50.41 $2,520,460.00
Disclosure

SEC source: 0000874015-20-000131 · edgar.xml · nonDerivative · entry 2

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Indirect · By trust

Disclosed balance after: 650,391

F2 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on January 2, 2020

F3 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $50.02 to $50.70, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (4) of this Form 4

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September 21, 2020 Filed Sep 23, 2020 22:44 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 2,000 $50.18 $100,360.00
Disclosure

SEC source: 0000874015-20-000131 · edgar.xml · nonDerivative · entry 1

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 1,581

F1 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person's wife on January 2, 2020.

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June 25, 2020 Filed Jun 26, 2020 23:47 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 9,914 $60.11 $595,906.75
Disclosure

SEC source: 0000874015-20-000076 · edgar.xml · nonDerivative · entry 2

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,021

F1 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on January 2, 2020.

F2 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $60.10 to $60.15, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (2) of this Form 4

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June 24, 2020 Filed Jun 26, 2020 23:47 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 5,000 $58.80 $294,000.00
Disclosure

SEC source: 0000874015-20-000076 · edgar.xml · nonDerivative · entry 1

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,935

F1 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on January 2, 2020.

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June 19, 2020 Filed Jun 19, 2020 23:03 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 10,000 $58.33 $583,250.00
Disclosure

SEC source: 0000874015-20-000072 · edgar.xml · nonDerivative · entry 3

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,935

F1 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on January 2, 2020.

F4 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $58.25 to $58.40, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (4) of this Form 4

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June 17, 2020 Filed Jun 19, 2020 23:03 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 2,000 $58.25 $116,500.00
Disclosure

SEC source: 0000874015-20-000072 · edgar.xml · nonDerivative · entry 2

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Indirect · By Wife

Disclosed balance after: 3,581

F3 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person's wife on January 2, 2020.

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June 17, 2020 Filed Jun 19, 2020 23:03 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 15,000 $57.90 $868,521.00
Disclosure

SEC source: 0000874015-20-000072 · edgar.xml · nonDerivative · entry 1

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,935

F1 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on January 2, 2020.

F2 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $57.59 to $58.36, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (2) of this Form 4

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March 25, 2020 Filed Mar 27, 2020 23:05 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 1,000 $47.00 $47,000.00
Disclosure

SEC source: 0000874015-20-000066 · edgar.xml · nonDerivative · entry 2

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Indirect · By Wife

Disclosed balance after: 5,581

F2 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person's wife on January 2, 2020.

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March 25, 2020 Filed Mar 27, 2020 23:05 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 15,000 $47.00 $705,000.00
Disclosure

SEC source: 0000874015-20-000066 · edgar.xml · nonDerivative · entry 1

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,935

F1 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on January 2, 2020.

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March 19, 2020 Filed Mar 23, 2020 22:17 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 1,000 $45.00 $45,000.00
Disclosure

SEC source: 0000874015-20-000062 · edgar.xml · nonDerivative · entry 3

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 6,581

F3 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person's wife on January 2, 2020.

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March 19, 2020 Filed Mar 23, 2020 22:17 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 5,000 $46.00 $230,000.00
Disclosure

SEC source: 0000874015-20-000062 · edgar.xml · nonDerivative · entry 2

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 56,545

F1 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on January 2, 2020.

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March 19, 2020 Filed Mar 23, 2020 22:17 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 10,000 $44.75 $447,546.00
Disclosure

SEC source: 0000874015-20-000062 · edgar.xml · nonDerivative · entry 1

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 61,545

F1 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on January 2, 2020.

F2 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $44.50 to $45.07, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (2) of this Form 4.

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March 17, 2020 Filed Mar 19, 2020 17:55 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCOMMON STOCK 4,349 $45.00 $195,705.00
Disclosure

SEC source: 0000874015-20-000060 · edgar.xml · nonDerivative · entry 4

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 71,545

F1 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on January 2, 2020.

Read SEC document
March 17, 2020 Filed Mar 19, 2020 17:55 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCOMMON STOCK 5,651 $45.00 $254,295.00
Disclosure

SEC source: 0000874015-20-000060 · edgar.xml · nonDerivative · entry 3

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 75,894

F1 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on January 2, 2020.

Read SEC document
March 17, 2020 Filed Mar 19, 2020 17:55 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCOMMON STOCK 5,421 $44.50 $241,234.50
Disclosure

SEC source: 0000874015-20-000060 · edgar.xml · nonDerivative · entry 2

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 81,545

F1 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on January 2, 2020.

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March 17, 2020 Filed Mar 19, 2020 17:55 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCOMMON STOCK 4,969 $44.50 $221,120.50
Disclosure

SEC source: 0000874015-20-000060 · edgar.xml · nonDerivative · entry 1

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 86,966

F1 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on January 2, 2020.

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March 17, 2020 Filed Mar 27, 2020 23:01 UTC Amendment IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 4,349 $45.00 $195,705.00
Disclosure

SEC source: 0000874015-20-000064 · edgar.xml · nonDerivative · entry 4

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 71,935

F1 · balance_after: The original Form 4 filed on March 19, 2020 reported 4,969 restricted stock units sold by the reporting person which has been revised by this amendment to reflect the actual amount of shares sold and beneficially owned by Mr. Crooke.

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March 17, 2020 Filed Mar 27, 2020 23:01 UTC Amendment IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 5,651 $45.00 $254,295.00
Disclosure

SEC source: 0000874015-20-000064 · edgar.xml · nonDerivative · entry 3

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 76,284

F1 · balance_after: The original Form 4 filed on March 19, 2020 reported 4,969 restricted stock units sold by the reporting person which has been revised by this amendment to reflect the actual amount of shares sold and beneficially owned by Mr. Crooke.

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March 17, 2020 Filed Mar 27, 2020 23:01 UTC Amendment IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 5,421 $44.50 $241,234.50
Disclosure

SEC source: 0000874015-20-000064 · edgar.xml · nonDerivative · entry 2

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 81,935

F1 · balance_after: The original Form 4 filed on March 19, 2020 reported 4,969 restricted stock units sold by the reporting person which has been revised by this amendment to reflect the actual amount of shares sold and beneficially owned by Mr. Crooke.

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March 17, 2020 Filed Mar 27, 2020 23:01 UTC Amendment IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 4,579 $44.50 $203,765.50
Disclosure

SEC source: 0000874015-20-000064 · edgar.xml · nonDerivative · entry 1

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 87,356

F1 · shares: The original Form 4 filed on March 19, 2020 reported 4,969 restricted stock units sold by the reporting person which has been revised by this amendment to reflect the actual amount of shares sold and beneficially owned by Mr. Crooke.

F1 · balance_after: The original Form 4 filed on March 19, 2020 reported 4,969 restricted stock units sold by the reporting person which has been revised by this amendment to reflect the actual amount of shares sold and beneficially owned by Mr. Crooke.

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January 15, 2020 Filed Jan 17, 2020 23:28 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionRestricted Stock Units · Derivative 3,317 $0.00 $0.00
Disclosure

SEC source: 0000874015-20-000029 · edgar.xml · derivative · entry 9

CROOKE STANLEY T · CIK 0000897667 · Director · Executive Chairman of Board

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 6,627

Underlying: Common Stock · 3,317 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_price: Each Restricted Stock Unit represents a contingent right to receive one share of Ionis common stock, or its equivalent cash value.

F5 · derivative.exercise_date: Restricted Stock Units vest in four equal annual installments. Upon vesting, the Restricted Stock Units will be paid out in whole shares of Ionis common stock or cash as may be determined by Ionis.

F5 · derivative.expiration_date: Restricted Stock Units vest in four equal annual installments. Upon vesting, the Restricted Stock Units will be paid out in whole shares of Ionis common stock or cash as may be determined by Ionis.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.