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person · Reporting owner

CROOKE STANLEY T

Disclosed activity across 2 companies

Tapewire entity
143377
SEC CIK
0000897667

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Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
AKCEA THERAPEUTICS, INC.AKCA · Entity 145982DirectorJuly 13, 2017July 13, 2017
IONIS PHARMACEUTICALS INCIONS · Entity 1182Director · Exec Chairman of the BoardJanuary 26, 2021January 29, 2021

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

AKCEA THERAPEUTICS, INC.

Report date July 13, 2017 · Filed July 13, 2017

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
No securities are beneficially owned.SEC Table I · non-derivativeDirect0 Reported balance Holding disclosure · report date 2017-07-13 · row 1 Holding and transaction disclosures are not merged.
1 source row

Row 1 · Balance 0

IONIS PHARMACEUTICALS INC

Report date January 26, 2021 · Filed January 29, 2021

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect2,021 Reported balance After 2021-01-26 transaction · row 1
1 source row

Row 1 · 2021-01-26 · Sale · Disposed 28,333 · Balance 2,021

F1: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on January 2, 2020.

F2: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $63.00 to $64.00, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (2) of this Form 4.

Common StockSEC Table I · non-derivativeIndirectBy wife3,111 Reported balance Holding disclosure · report date 2021-01-26 · row 2 Holding and transaction disclosures are not merged.
1 source row

Row 2 · Balance 3,111

Common StockSEC Table I · non-derivativeIndirectBy trust494,391 Reported balance Holding disclosure · report date 2021-01-26 · row 3 Holding and transaction disclosures are not merged.
1 source row

Row 3 · Balance 494,391

Filing footnotes · ownership attribution and instrument terms

F1: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on January 2, 2020.

F2: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $63.00 to $64.00, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (2) of this Form 4.

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
January 15, 2020 Filed Jan 17, 2020 23:28 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionRestricted Stock Units · Derivative 39,643 $0.00 $0.00
Disclosure

SEC source: 0000874015-20-000029 · edgar.xml · derivative · entry 8

CROOKE STANLEY T · CIK 0000897667 · Director · Executive Chairman of Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 72,160

Underlying: Common Stock · 39,643 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_price: Each Restricted Stock Unit represents a contingent right to receive one share of Ionis common stock, or its equivalent cash value.

F5 · derivative.exercise_date: Restricted Stock Units vest in four equal annual installments. Upon vesting, the Restricted Stock Units will be paid out in whole shares of Ionis common stock or cash as may be determined by Ionis.

F5 · derivative.expiration_date: Restricted Stock Units vest in four equal annual installments. Upon vesting, the Restricted Stock Units will be paid out in whole shares of Ionis common stock or cash as may be determined by Ionis.

Read SEC document
January 15, 2020 Filed Jan 17, 2020 23:28 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 GrantRestricted Stock Units · Derivative 5,545 $0.00 $0.00
Disclosure

SEC source: 0000874015-20-000029 · edgar.xml · derivative · entry 7

CROOKE STANLEY T · CIK 0000897667 · Director · Executive Chairman of Board

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 5,545

Underlying: Common Stock · 5,545 shares

Expires not disclosed

F4 · derivative.exercise_price: Each Restricted Stock Unit represents a contingent right to receive one share of Ionis common stock, or its equivalent cash value.

F6 · derivative.exercise_price: Grant to reporting person's wife of Restricted Stock Units under the Ionis Pharmaceuticals, Inc. 2011 Equity Incentive Plan.

F5 · derivative.exercise_date: Restricted Stock Units vest in four equal annual installments. Upon vesting, the Restricted Stock Units will be paid out in whole shares of Ionis common stock or cash as may be determined by Ionis.

F5 · derivative.expiration_date: Restricted Stock Units vest in four equal annual installments. Upon vesting, the Restricted Stock Units will be paid out in whole shares of Ionis common stock or cash as may be determined by Ionis.

Read SEC document
January 15, 2020 Filed Jan 17, 2020 23:28 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 GrantRestricted Stock Units · Derivative 62,982 $0.00 $0.00
Disclosure

SEC source: 0000874015-20-000029 · edgar.xml · derivative · entry 6

CROOKE STANLEY T · CIK 0000897667 · Director · Executive Chairman of Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 62,982

Underlying: Common Stock · 62,982 shares

Expires not disclosed

F3 · derivative.exercise_price: Grant to reporting person of Restricted Stock Units under the Ionis Pharmaceuticals, Inc. Amended and Restated 2011 Equity Incentive Plan.

F4 · derivative.exercise_price: Each Restricted Stock Unit represents a contingent right to receive one share of Ionis common stock, or its equivalent cash value.

F5 · derivative.exercise_date: Restricted Stock Units vest in four equal annual installments. Upon vesting, the Restricted Stock Units will be paid out in whole shares of Ionis common stock or cash as may be determined by Ionis.

F5 · derivative.expiration_date: Restricted Stock Units vest in four equal annual installments. Upon vesting, the Restricted Stock Units will be paid out in whole shares of Ionis common stock or cash as may be determined by Ionis.

Read SEC document
January 15, 2020 Filed Jan 17, 2020 23:28 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Tax withholdingCommon Stock 1,268 $62.06 $78,692.08
Disclosure

SEC source: 0000874015-20-000029 · edgar.xml · nonDerivative · entry 4

CROOKE STANLEY T · CIK 0000897667 · Director · Executive Chairman of Board

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 7,581

F2 · kind: Shares withheld to cover the required tax withholding obligations pursuant to the Ionis Pharmaceuticals, Inc. Amended and Restated 2011 Equity Incentive Plan.

F2 · shares: Shares withheld to cover the required tax withholding obligations pursuant to the Ionis Pharmaceuticals, Inc. Amended and Restated 2011 Equity Incentive Plan.

Read SEC document
January 15, 2020 Filed Jan 17, 2020 23:28 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionCommon Stock 3,317 $0.00 $0.00
Disclosure

SEC source: 0000874015-20-000029 · edgar.xml · nonDerivative · entry 3

CROOKE STANLEY T · CIK 0000897667 · Director · Executive Chairman of Board

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 8,849

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired pursuant to vesting and release of shares in accordance with Restricted Stock Unit awards.

F1 · shares: Acquired pursuant to vesting and release of shares in accordance with Restricted Stock Unit awards.

Read SEC document
January 15, 2020 Filed Jan 17, 2020 23:28 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Tax withholdingCommon Stock 17,342 $62.06 $1,076,244.52
Disclosure

SEC source: 0000874015-20-000029 · edgar.xml · nonDerivative · entry 2

CROOKE STANLEY T · CIK 0000897667 · Director · Executive Chairman of Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 91,935

F2 · kind: Shares withheld to cover the required tax withholding obligations pursuant to the Ionis Pharmaceuticals, Inc. Amended and Restated 2011 Equity Incentive Plan.

F2 · shares: Shares withheld to cover the required tax withholding obligations pursuant to the Ionis Pharmaceuticals, Inc. Amended and Restated 2011 Equity Incentive Plan.

Read SEC document
January 15, 2020 Filed Jan 17, 2020 23:28 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionCommon Stock 39,643 $0.00 $0.00
Disclosure

SEC source: 0000874015-20-000029 · edgar.xml · nonDerivative · entry 1

CROOKE STANLEY T · CIK 0000897667 · Director · Executive Chairman of Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 109,277

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired pursuant to vesting and release of shares in accordance with Restricted Stock Unit awards.

F1 · shares: Acquired pursuant to vesting and release of shares in accordance with Restricted Stock Unit awards.

Read SEC document
January 02, 2020 Filed Jan 3, 2020 23:56 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 GrantEmployee Stock Option (right to buy) · Derivative 12,477 $0.00 Strike: $60.89 $0.00
Disclosure

SEC source: 0000874015-20-000008 · edgar.xml · derivative · entry 2

CROOKE STANLEY T · CIK 0000897667 · Director · Executive Chairman of Board

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 12,477

Underlying: Common Stock · 12,477 shares

Expires 2027-01-01

F1 · derivative.exercise_date: Grant on 01/02/2020 to reporting person or reporting person's wife (as indicated) of stock options under the Ionis Pharmaceuticals, Inc. Amended and Restated 2011 Equity Incentive Plan. Following this transaction, the option was exercisable as to 0 shares on 01/02/2020. 25% of the shares subject to the option will vest and become exercisable on 01/02/2021. Thereafter, the remaining shares subject to the option will vest and become exercisable in 36 equal monthly installments over the next 3 years.

Read SEC document
January 02, 2020 Filed Jan 3, 2020 23:56 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 GrantEmployee Stock Option (right to buy) · Derivative 141,709 $0.00 Strike: $60.89 $0.00
Disclosure

SEC source: 0000874015-20-000008 · edgar.xml · derivative · entry 1

CROOKE STANLEY T · CIK 0000897667 · Director · Executive Chairman of Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 141,709

Underlying: Common Stock · 141,709 shares

Expires 2027-01-01

F1 · derivative.exercise_date: Grant on 01/02/2020 to reporting person or reporting person's wife (as indicated) of stock options under the Ionis Pharmaceuticals, Inc. Amended and Restated 2011 Equity Incentive Plan. Following this transaction, the option was exercisable as to 0 shares on 01/02/2020. 25% of the shares subject to the option will vest and become exercisable on 01/02/2021. Thereafter, the remaining shares subject to the option will vest and become exercisable in 36 equal monthly installments over the next 3 years.

Read SEC document
December 06, 2019 Filed Jan 3, 2020 23:50 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 GiftCommon Stock 25,000 $0.00 $0.00
Disclosure

SEC source: 0000874015-20-000004 · edgar.xml · nonDerivative · entry 1

CROOKE STANLEY T · CIK 0000897667 · Director · Executive Chairman of Board

10b5-1 filing: Not disclosed

Ownership: Indirect · By trust

Disclosed balance after: 700,391

F1 · kind: Represents a bona fide gift to a charitable organization.

Read SEC document
August 21, 2019 Filed Aug 22, 2019 22:41 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionEmployee Stock Option (right to buy) · Derivative 10,000 $0.00 Strike: $39.87 $0.00
Disclosure

SEC source: 0000874015-19-000118 · edgar.xml · derivative · entry 10

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,180

Underlying: Common Stock · 10,000 shares

Expires 2021-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
August 21, 2019 Filed Aug 22, 2019 22:41 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 10,000 $72.15 $721,500.00
Disclosure

SEC source: 0000874015-19-000118 · edgar.xml · nonDerivative · entry 6

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 69,634

F1 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 3/13/2019.

F1 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 3/13/2019.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $72.10 to $72.20, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (3) on this Form 4.

Read SEC document
August 21, 2019 Filed Aug 22, 2019 22:41 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionCommon Stock 10,000 $39.87 $398,700.00
Disclosure

SEC source: 0000874015-19-000118 · edgar.xml · nonDerivative · entry 5

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 79,634

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 3/13/2019.

F1 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 3/13/2019.

Read SEC document
August 20, 2019 Filed Aug 22, 2019 22:41 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionEmployee Stock Option (right to buy) · Derivative 2,000 $0.00 Strike: $39.87 $0.00
Disclosure

SEC source: 0000874015-19-000118 · edgar.xml · derivative · entry 9

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 500

Underlying: Common Stock · 2,000 shares

Expires 2021-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
August 20, 2019 Filed Aug 22, 2019 22:41 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionEmployee Stock Option (right to buy) · Derivative 10,000 $0.00 Strike: $39.87 $0.00
Disclosure

SEC source: 0000874015-19-000118 · edgar.xml · derivative · entry 8

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 37,180

Underlying: Common Stock · 10,000 shares

Expires 2021-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
August 20, 2019 Filed Aug 22, 2019 22:41 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 2,000 $71.00 $142,000.00
Disclosure

SEC source: 0000874015-19-000118 · edgar.xml · nonDerivative · entry 4

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 5,532

F2 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 3/13/2019.

F2 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 3/13/2019.

Read SEC document
August 20, 2019 Filed Aug 22, 2019 22:41 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionCommon Stock 2,000 $39.87 $79,740.00
Disclosure

SEC source: 0000874015-19-000118 · edgar.xml · nonDerivative · entry 3

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 7,532

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 3/13/2019.

F2 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 3/13/2019.

Read SEC document
August 20, 2019 Filed Aug 22, 2019 22:41 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 10,000 $71.00 $710,000.00
Disclosure

SEC source: 0000874015-19-000118 · edgar.xml · nonDerivative · entry 2

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 69,634

F1 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 3/13/2019.

F1 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 3/13/2019.

Read SEC document
August 20, 2019 Filed Aug 22, 2019 22:41 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionCommon Stock 10,000 $39.87 $398,700.00
Disclosure

SEC source: 0000874015-19-000118 · edgar.xml · nonDerivative · entry 1

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 79,634

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 3/13/2019.

F1 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 3/13/2019.

Read SEC document
July 18, 2019 Filed Jul 22, 2019 21:34 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionEmployee Stock Option (right to buy) · Derivative 10,000 $0.00 Strike: $39.87 $0.00
Disclosure

SEC source: 0000874015-19-000116 · edgar.xml · derivative · entry 4

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 47,180

Underlying: Common Stock · 10,000 shares

Expires 2021-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
July 18, 2019 Filed Jul 22, 2019 21:34 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 10,000 $70.25 $702,506.00
Disclosure

SEC source: 0000874015-19-000116 · edgar.xml · nonDerivative · entry 2

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 69,634

F1 · kind: Acquired as a result of exercising a stock option pursuant to a Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effected pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on 3/13/2019.

F1 · shares: Acquired as a result of exercising a stock option pursuant to a Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effected pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on 3/13/2019.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $70.25 to $70.26, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (2) on this Form 4.

Read SEC document
July 18, 2019 Filed Jul 22, 2019 21:34 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionCommon Stock 10,000 $39.87 $398,700.00
Disclosure

SEC source: 0000874015-19-000116 · edgar.xml · nonDerivative · entry 1

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 79,634

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired as a result of exercising a stock option pursuant to a Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effected pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on 3/13/2019.

F1 · shares: Acquired as a result of exercising a stock option pursuant to a Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effected pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on 3/13/2019.

Read SEC document
April 16, 2019 Filed Apr 17, 2019 23:30 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionEmployee Stock Option (right to buy) · Derivative 700 $0.00 Strike: $39.87 $0.00
Disclosure

SEC source: 0000874015-19-000061 · edgar.xml · derivative · entry 19

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 2,500

Underlying: Common Stock · 700 shares

Expires 2021-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 16, 2019 Filed Apr 17, 2019 23:30 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionEmployee Stock Option (right to buy) · Derivative 300 $0.00 Strike: $10.82 $0.00
Disclosure

SEC source: 0000874015-19-000061 · edgar.xml · derivative · entry 18

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 0

Underlying: Common Stock · 300 shares

Expires 2020-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 16, 2019 Filed Apr 17, 2019 23:30 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionEmployee Stock Option (right to buy) · Derivative 13,320 $0.00 Strike: $39.87 $0.00
Disclosure

SEC source: 0000874015-19-000061 · edgar.xml · derivative · entry 17

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 57,180

Underlying: Common Stock · 13,320 shares

Expires 2021-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 16, 2019 Filed Apr 17, 2019 23:30 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionEmployee Stock Option (right to buy) · Derivative 6,680 $0.00 Strike: $14.69 $0.00
Disclosure

SEC source: 0000874015-19-000061 · edgar.xml · derivative · entry 16

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 6,680 shares

Expires 2020-01-29

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 16, 2019 Filed Apr 17, 2019 23:30 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 700 $84.75 $59,325.00
Disclosure

SEC source: 0000874015-19-000061 · edgar.xml · nonDerivative · entry 12

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 5,532

F2 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 3/13/2019.

F2 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 3/13/2019.

Read SEC document
April 16, 2019 Filed Apr 17, 2019 23:30 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionCommon Stock 700 $39.87 $27,909.00
Disclosure

SEC source: 0000874015-19-000061 · edgar.xml · nonDerivative · entry 11

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 6,232

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 3/13/2019.

F2 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 3/13/2019.

Read SEC document
April 16, 2019 Filed Apr 17, 2019 23:30 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 300 $84.75 $25,425.00
Disclosure

SEC source: 0000874015-19-000061 · edgar.xml · nonDerivative · entry 10

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 5,532

F2 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 3/13/2019.

F2 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 3/13/2019.

Read SEC document
April 16, 2019 Filed Apr 17, 2019 23:30 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionCommon Stock 300 $10.82 $3,246.00
Disclosure

SEC source: 0000874015-19-000061 · edgar.xml · nonDerivative · entry 9

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 5,832

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 3/13/2019.

F2 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 3/13/2019.

Read SEC document
April 16, 2019 Filed Apr 17, 2019 23:30 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 13,320 $84.56 $1,126,369.84
Disclosure

SEC source: 0000874015-19-000061 · edgar.xml · nonDerivative · entry 8

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 69,634

F1 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 3/13/2019.

F1 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 3/13/2019.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $84.50 to $84.75, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (3) on this Form 4.

Read SEC document
April 16, 2019 Filed Apr 17, 2019 23:30 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionCommon Stock 13,320 $39.87 $531,068.40
Disclosure

SEC source: 0000874015-19-000061 · edgar.xml · nonDerivative · entry 7

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 82,954

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 3/13/2019.

F1 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 3/13/2019.

Read SEC document
April 16, 2019 Filed Apr 17, 2019 23:30 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 6,680 $84.75 $566,130.00
Disclosure

SEC source: 0000874015-19-000061 · edgar.xml · nonDerivative · entry 6

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 69,634

F1 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 3/13/2019.

F1 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 3/13/2019.

Read SEC document
April 16, 2019 Filed Apr 17, 2019 23:30 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionCommon Stock 6,680 $14.69 $98,129.20
Disclosure

SEC source: 0000874015-19-000061 · edgar.xml · nonDerivative · entry 5

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 76,314

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 3/13/2019.

F1 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 3/13/2019.

Read SEC document
April 15, 2019 Filed Apr 17, 2019 23:30 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionEmployee Stock Option (right to buy) · Derivative 1,000 $0.00 Strike: $10.82 $0.00
Disclosure

SEC source: 0000874015-19-000061 · edgar.xml · derivative · entry 15

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 300

Underlying: Common Stock · 1,000 shares

Expires 2020-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 15, 2019 Filed Apr 17, 2019 23:30 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionEmployee Stock Option (right to buy) · Derivative 10,000 $0.00 Strike: $14.69 $0.00
Disclosure

SEC source: 0000874015-19-000061 · edgar.xml · derivative · entry 14

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,680

Underlying: Common Stock · 10,000 shares

Expires 2020-01-29

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 15, 2019 Filed Apr 17, 2019 23:30 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 1,000 $85.25 $85,250.00
Disclosure

SEC source: 0000874015-19-000061 · edgar.xml · nonDerivative · entry 4

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 5,532

F2 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 3/13/2019.

F2 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 3/13/2019.

Read SEC document
April 15, 2019 Filed Apr 17, 2019 23:30 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionCommon Stock 1,000 $10.82 $10,820.00
Disclosure

SEC source: 0000874015-19-000061 · edgar.xml · nonDerivative · entry 3

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 6,532

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 3/13/2019.

F2 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 3/13/2019.

Read SEC document
April 15, 2019 Filed Apr 17, 2019 23:30 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 10,000 $85.25 $852,500.00
Disclosure

SEC source: 0000874015-19-000061 · edgar.xml · nonDerivative · entry 2

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 69,634

F1 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 3/13/2019.

F1 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 3/13/2019.

Read SEC document
April 15, 2019 Filed Apr 17, 2019 23:30 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionCommon Stock 10,000 $14.69 $146,900.00
Disclosure

SEC source: 0000874015-19-000061 · edgar.xml · nonDerivative · entry 1

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 79,634

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 3/13/2019.

F1 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 3/13/2019.

Read SEC document
February 26, 2019 Filed Feb 28, 2019 00:31 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionEmployee Stock Option (right to buy) · Derivative 37,000 $0.00 Strike: $39.87 $0.00
Disclosure

SEC source: 0000874015-19-000042 · edgar.xml · derivative · entry 7

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 70,500

Underlying: Common Stock · 37,000 shares

Expires 2021-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 26, 2019 Filed Feb 28, 2019 00:31 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 37,000 $61.54 $2,276,798.70
Disclosure

SEC source: 0000874015-19-000042 · edgar.xml · nonDerivative · entry 4

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 69,634

F1 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/17/2016.

F1 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/17/2016.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $61.45 to $61.68, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (3) on this Form 4.

Read SEC document
February 26, 2019 Filed Feb 28, 2019 00:31 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionCommon Stock 37,000 $39.87 $1,475,190.00
Disclosure

SEC source: 0000874015-19-000042 · edgar.xml · nonDerivative · entry 3

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 106,634

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/17/2016.

F1 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/17/2016.

Read SEC document
February 25, 2019 Filed Feb 28, 2019 00:31 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionEmployee Stock Option (right to buy) · Derivative 40,000 $0.00 Strike: $39.87 $0.00
Disclosure

SEC source: 0000874015-19-000042 · edgar.xml · derivative · entry 6

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 107,500

Underlying: Common Stock · 40,000 shares

Expires 2021-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 25, 2019 Filed Feb 28, 2019 00:31 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 40,000 $60.07 $2,402,700.00
Disclosure

SEC source: 0000874015-19-000042 · edgar.xml · nonDerivative · entry 2

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 69,634

F1 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/17/2016.

F1 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/17/2016.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $60.02 to $60.15, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (2) on this Form 4.

Read SEC document
February 25, 2019 Filed Feb 28, 2019 00:31 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionCommon Stock 40,000 $39.87 $1,594,800.00
Disclosure

SEC source: 0000874015-19-000042 · edgar.xml · nonDerivative · entry 1

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 109,634

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/17/2016.

F1 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/17/2016.

Read SEC document
February 13, 2019 Filed Feb 14, 2019 22:57 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionEmployee Stock Option (right to buy) · Derivative 5,300 $0.00 Strike: $39.87 $0.00
Disclosure

SEC source: 0000874015-19-000038 · edgar.xml · derivative · entry 10

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 3,200

Underlying: Common Stock · 5,300 shares

Expires 2021-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 13, 2019 Filed Feb 14, 2019 22:57 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionEmployee Stock Option (right to buy) · Derivative 1,604 $0.00 Strike: $10.82 $0.00
Disclosure

SEC source: 0000874015-19-000038 · edgar.xml · derivative · entry 9

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 1,300

Underlying: Common Stock · 1,604 shares

Expires 2020-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 13, 2019 Filed Feb 14, 2019 22:57 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionEmployee Stock Option (right to buy) · Derivative 40,000 $0.00 Strike: $39.87 $0.00
Disclosure

SEC source: 0000874015-19-000038 · edgar.xml · derivative · entry 8

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 147,500

Underlying: Common Stock · 40,000 shares

Expires 2021-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 13, 2019 Filed Feb 14, 2019 22:57 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 5,300 $60.00 $318,000.00
Disclosure

SEC source: 0000874015-19-000038 · edgar.xml · nonDerivative · entry 6

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 5,532

F2 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 6/17/2016.

F2 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 6/17/2016.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.