GUTHART GARY S

SEC source: 0001280628-26-000014 · edgardoc.xml · nonDerivative · entry 1

GUTHART GARY S · CIK 0001280628 · Director

10b5-1 filing: Plan reported

Ownership: Indirect · by Trust

Disclosed balance after: 1,245,679

F1 · kind: The transaction took place in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on June 15, 2027.

SEC source: 0001280628-26-000012 · edgardoc.xml · derivative · entry 1

GUTHART GARY S · CIK 0001280628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 554

Underlying: Common Stock · 554 shares

Expires not disclosed

F1 · derivative.exercise_date: 100% of the RSUs shall vest on the earlier of the one year anniversary of the date of grant or the next Annual Meeting of Stockholders, subject to the Reporting Person's continued service.

F1 · derivative.expiration_date: 100% of the RSUs shall vest on the earlier of the one year anniversary of the date of grant or the next Annual Meeting of Stockholders, subject to the Reporting Person's continued service.

SEC source: 0001280628-26-000010 · edgardoc.xml · derivative · entry 9

GUTHART GARY S · CIK 0001280628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 2,506 shares

Expires 2026-02-28

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: Each RSU granted represents a contingent right to receive one share of Intuitive Surgical common stock. The grant vests 25% on the first anniversary of the date of grant and annually thereafter, over a four year period.

F4 · derivative.expiration_date: Each RSU granted represents a contingent right to receive one share of Intuitive Surgical common stock. The grant vests 25% on the first anniversary of the date of grant and annually thereafter, over a four year period.

SEC source: 0001280628-26-000010 · edgardoc.xml · derivative · entry 8

GUTHART GARY S · CIK 0001280628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 26,334 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Represents performance stock units ("PSUs") initially granted to the Reporting Person on February 28, 2023 subject to achievement of certain performance metrics. The performance criteria for the PSUs reported herein have been achieved, as determined by the Compensation Committee of the Issuer. The PSUs reported herein vest on February 28, 2026, the third anniversary of the grant date, subject to Reporting Person's continuous service to the Issuer through each such vesting date.

F2 · derivative.expiration_date: Represents performance stock units ("PSUs") initially granted to the Reporting Person on February 28, 2023 subject to achievement of certain performance metrics. The performance criteria for the PSUs reported herein have been achieved, as determined by the Compensation Committee of the Issuer. The PSUs reported herein vest on February 28, 2026, the third anniversary of the grant date, subject to Reporting Person's continuous service to the Issuer through each such vesting date.

SEC source: 0001280628-26-000010 · edgardoc.xml · nonDerivative · entry 4

GUTHART GARY S · CIK 0001280628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 23,789

F3 · kind: This transaction represents the withholding of shares to cover taxes applicable to a settlement of PSUs reported on this Form 4.

SEC source: 0001280628-26-000010 · edgardoc.xml · nonDerivative · entry 3

GUTHART GARY S · CIK 0001280628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 36,848

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · kind: Represents performance stock units ("PSUs") initially granted to the Reporting Person on February 28, 2023 subject to achievement of certain performance metrics. The performance criteria for the PSUs reported herein have been achieved, as determined by the Compensation Committee of the Issuer. The PSUs reported herein vest on February 28, 2026, the third anniversary of the grant date, subject to Reporting Person's continuous service to the Issuer through each such vesting date.

SEC source: 0001280628-26-000010 · edgardoc.xml · nonDerivative · entry 2

GUTHART GARY S · CIK 0001280628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,514

F1 · kind: RSUs vest 25% per year over a four year period, commencing on the first anniversary of the grant date. RSUs convert into common stock on the vest date on a one-for-one basis. 25% of the shares have been released and a portion of the shares were held back to cover the statutory tax withholding requirements. The net shares were deposited into the holders account.

SEC source: 0001280628-26-000010 · edgardoc.xml · nonDerivative · entry 1

GUTHART GARY S · CIK 0001280628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 11,757

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: RSUs vest 25% per year over a four year period, commencing on the first anniversary of the grant date. RSUs convert into common stock on the vest date on a one-for-one basis. 25% of the shares have been released and a portion of the shares were held back to cover the statutory tax withholding requirements. The net shares were deposited into the holders account.

SEC source: 0001280628-26-000008 · edgardoc.xml · derivative · entry 10

GUTHART GARY S · CIK 0001280628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,299

Underlying: Common Stock · 3,433 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: Each RSU granted represents a contingent right to receive one share of Intuitive Surgical common stock. The grant vests 25% on the first anniversary of the date of grant and annually thereafter, over a four year period.

F3 · derivative.expiration_date: Each RSU granted represents a contingent right to receive one share of Intuitive Surgical common stock. The grant vests 25% on the first anniversary of the date of grant and annually thereafter, over a four year period.

SEC source: 0001280628-26-000008 · edgardoc.xml · derivative · entry 9

GUTHART GARY S · CIK 0001280628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,920

Underlying: Common Stock · 4,960 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: Each RSU granted represents a contingent right to receive one share of Intuitive Surgical common stock. The grant vests 25% on the first anniversary of the date of grant and annually thereafter, over a four year period.

F3 · derivative.expiration_date: Each RSU granted represents a contingent right to receive one share of Intuitive Surgical common stock. The grant vests 25% on the first anniversary of the date of grant and annually thereafter, over a four year period.

SEC source: 0001280628-26-000008 · edgardoc.xml · derivative · entry 8

GUTHART GARY S · CIK 0001280628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 26,334

Underlying: Common Stock · 8,778 shares

Expires not disclosed

F2 · derivative.exercise_date: Represents performance stock units ("PSUs") initially granted to the Reporting Person on February 28, 2023 subject to achievement of certain performance metrics. The performance criteria for the PSUs reported herein have been achieved, as determined by the Compensation Committee of the Issuer. The PSUs reported herein vest on February 28, 2026, the third anniversary of the grant date, subject to Reporting Person's continuous service to the Issuer through each such vesting date.

F2 · derivative.expiration_date: Represents performance stock units ("PSUs") initially granted to the Reporting Person on February 28, 2023 subject to achievement of certain performance metrics. The performance criteria for the PSUs reported herein have been achieved, as determined by the Compensation Committee of the Issuer. The PSUs reported herein vest on February 28, 2026, the third anniversary of the grant date, subject to Reporting Person's continuous service to the Issuer through each such vesting date.

SEC source: 0001280628-26-000008 · edgardoc.xml · nonDerivative · entry 4

GUTHART GARY S · CIK 0001280628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,251

F1 · kind: RSUs vest 25% per year over a four year period, commencing on the first anniversary of the grant date. RSUs convert into common stock on the vest date on a one-for-one basis. 25% of the shares have been released and a portion of the shares were held back to cover the statutory tax withholding requirements. The net shares were deposited into the holders account.

SEC source: 0001280628-26-000008 · edgardoc.xml · nonDerivative · entry 3

GUTHART GARY S · CIK 0001280628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,954

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: RSUs vest 25% per year over a four year period, commencing on the first anniversary of the grant date. RSUs convert into common stock on the vest date on a one-for-one basis. 25% of the shares have been released and a portion of the shares were held back to cover the statutory tax withholding requirements. The net shares were deposited into the holders account.

SEC source: 0001280628-26-000008 · edgardoc.xml · nonDerivative · entry 2

GUTHART GARY S · CIK 0001280628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,521

F1 · kind: RSUs vest 25% per year over a four year period, commencing on the first anniversary of the grant date. RSUs convert into common stock on the vest date on a one-for-one basis. 25% of the shares have been released and a portion of the shares were held back to cover the statutory tax withholding requirements. The net shares were deposited into the holders account.

SEC source: 0001280628-26-000008 · edgardoc.xml · nonDerivative · entry 1

GUTHART GARY S · CIK 0001280628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,981

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: RSUs vest 25% per year over a four year period, commencing on the first anniversary of the grant date. RSUs convert into common stock on the vest date on a one-for-one basis. 25% of the shares have been released and a portion of the shares were held back to cover the statutory tax withholding requirements. The net shares were deposited into the holders account.

SEC source: 0001280628-26-000006 · edgardoc.xml · derivative · entry 6

GUTHART GARY S · CIK 0001280628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,633

Underlying: Common Stock · 2,633 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Constitute restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of Issuer common stock upon vesting. 25% of the RSUs shall vest on each anniversary of February 10, 2023, subject to Reporting Person's continuous service to the Issuer through each such vesting date.

F2 · derivative.expiration_date: Constitute restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of Issuer common stock upon vesting. 25% of the RSUs shall vest on each anniversary of February 10, 2023, subject to Reporting Person's continuous service to the Issuer through each such vesting date.

SEC source: 0001280628-26-000006 · edgardoc.xml · nonDerivative · entry 2

GUTHART GARY S · CIK 0001280628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,021

F1 · kind: RSUs vest 25% per year over a four year period, commencing on each anniversary of February 10, 2023. RSUs convert into common stock on the vest date on a one-for-one basis. 25% of the shares have been released and a portion of the shares were held back to cover the statutory tax withholding requirements. The net shares were deposited into the holders account.

SEC source: 0001280628-26-000006 · edgardoc.xml · nonDerivative · entry 1

GUTHART GARY S · CIK 0001280628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,327

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: RSUs vest 25% per year over a four year period, commencing on each anniversary of February 10, 2023. RSUs convert into common stock on the vest date on a one-for-one basis. 25% of the shares have been released and a portion of the shares were held back to cover the statutory tax withholding requirements. The net shares were deposited into the holders account.

SEC source: 0001280628-26-000004 · edgardoc.xml · derivative · entry 2

GUTHART GARY S · CIK 0001280628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 17,556

Underlying: Common Stock · 17,556 shares

Expires not disclosed

F2 · derivative.exercise_date: Represents performance stock units ("PSUs") initially granted to the Reporting Person on February 28, 2023 subject to achievement of certain performance metrics. The performance criteria for the PSUs reported herein have been achieved, as determined by the Compensation Committee of the Issuer. The PSUs reported herein vest on February 28, 2026, the third anniversary of the grant date, subject to Reporting Person's continuous service to the Issuer through each such vesting date.

F2 · derivative.expiration_date: Represents performance stock units ("PSUs") initially granted to the Reporting Person on February 28, 2023 subject to achievement of certain performance metrics. The performance criteria for the PSUs reported herein have been achieved, as determined by the Compensation Committee of the Issuer. The PSUs reported herein vest on February 28, 2026, the third anniversary of the grant date, subject to Reporting Person's continuous service to the Issuer through each such vesting date.

SEC source: 0001280628-26-000004 · edgardoc.xml · derivative · entry 1

GUTHART GARY S · CIK 0001280628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,267

Underlying: Common Stock · 8,267 shares

Expires not disclosed

F1 · derivative.exercise_date: Represents performance stock units ("PSUs") initially granted to the Reporting Person on February 26, 2024 subject to achievement of certain performance metrics. The performance criteria for the PSUs reported herein have been achieved, as determined by the Compensation Committee of the Issuer. The PSUs reported herein vest on February 26, 2027, the third anniversary of the grant date, subject to Reporting Person's continuous service to the Issuer through each such vesting date.

F1 · derivative.expiration_date: Represents performance stock units ("PSUs") initially granted to the Reporting Person on February 26, 2024 subject to achievement of certain performance metrics. The performance criteria for the PSUs reported herein have been achieved, as determined by the Compensation Committee of the Issuer. The PSUs reported herein vest on February 26, 2027, the third anniversary of the grant date, subject to Reporting Person's continuous service to the Issuer through each such vesting date.

SEC source: 0001280628-26-000002 · edgardoc.xml · derivative · entry 6

GUTHART GARY S · CIK 0001280628 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 25,500 shares

Expires 2028-08-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transaction took place in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on April 28, 2026.

F5 · derivative.exercise_date: Non-statutory stock option granted pursuant to the 2010 Incentive Award Plan. Option shall vest 7/48 one month after the date of grant and 1/48 each month thereafter.

SEC source: 0001280628-26-000002 · edgardoc.xml · nonDerivative · entry 4

GUTHART GARY S · CIK 0001280628 · Director

10b5-1 filing: Plan reported

Ownership: Indirect · Trust FBO Son

Disclosed balance after: 15,720

F1 · kind: The transaction took place in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on April 28, 2026.

F4 · price: The price reported in Column 4 is a weighted average sale price. These shares were sold in multiple transactions at prices ranging from $529.77 to $534.00 as follows: 520 shares sold at $529.77 to $530.61; 360 shares sold at $530.98 to $531.86; 240 shares sold at $532.05 to $532.61; and 280 shares sold at $533.82 to $534.00. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

SEC source: 0001280628-26-000002 · edgardoc.xml · nonDerivative · entry 3

GUTHART GARY S · CIK 0001280628 · Director

10b5-1 filing: Plan reported

Ownership: Indirect · Trust FBO Daughter

Disclosed balance after: 15,720

F1 · kind: The transaction took place in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on April 28, 2026.

F3 · price: The price reported in Column 4 is a weighted average sale price. These shares were sold in multiple transactions at prices ranging from $529.77 to $534.00 as follows: 520 shares sold at $529.77 to $530.61; 298 shares sold at $530.98 to $531.87; 302 shares sold at $532.05 to $532.61; and 280 shares sold at $533.82 to $534.00. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

SEC source: 0001280628-26-000002 · edgardoc.xml · nonDerivative · entry 2

GUTHART GARY S · CIK 0001280628 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 3,694

F1 · kind: The transaction took place in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on April 28, 2026.

F2 · price: The price reported in Column 4 is a weighted average sale price. These shares were sold in multiple transactions at prices ranging from $525.51 to $534.00 as follows: 2,500 shares sold at $525.51 to $525.71; 280 shares sold at $526.94 to $527.41; 2,252 shares sold at $528.23 to $529.18; 9,860 shares sold at $529.27 to $530.27; 3,475 shares sold at $530.29 to $531.22; 1,589 shares sold at $531.37 to $532.24; 3,704 shares sold at $532.53 to $533.41; and 840 shares sold at $533.82 to $534.00. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

SEC source: 0001280628-26-000002 · edgardoc.xml · nonDerivative · entry 1

GUTHART GARY S · CIK 0001280628 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 28,194

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transaction took place in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on April 28, 2026.

SEC source: 0001280628-25-000006 · edgardoc.xml · derivative · entry 6

GUTHART GARY S · CIK 0001280628 · Director · Executive Chair of the Board o

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 25,500 shares

Expires 2028-02-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transaction took place in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on April 28, 2026.

F3 · derivative.exercise_date: Non-statutory stock option granted pursuant to the 2010 Incentive Award Plan. The option vests 1/8th six months after the date of grant and 1/48th monthly thereafter.

SEC source: 0001280628-25-000006 · edgardoc.xml · nonDerivative · entry 2

GUTHART GARY S · CIK 0001280628 · Director · Executive Chair of the Board o

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 2,694

F1 · kind: The transaction took place in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on April 28, 2026.

F2 · price: The price reported in Column 4 is a weighted average sale price. These shares were sold in multiple transactions at prices ranging from $568.62 to $573.54 as follows: 5,550 shares sold at $568.62 to $569.62; 6,304 shares sold at $569.64 to $570.63; 2,285 shares sold at $570.66 to $571.61; 5,528 shares sold at $571.70 to $572.70; 3,139 shares sold at $572.72 to $573.54. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

SEC source: 0001280628-25-000006 · edgardoc.xml · nonDerivative · entry 1

GUTHART GARY S · CIK 0001280628 · Director · Executive Chair of the Board o

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 25,500

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transaction took place in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on April 28, 2026.

SEC source: 0001280628-25-000004 · edgardoc.xml · derivative · entry 6

GUTHART GARY S · CIK 0001280628 · Director · Executive Chair of the Board o

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 36,000 shares

Expires 2027-08-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transaction took place in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on April 28, 2026.

F5 · derivative.exercise_date: Non-statutory stock option granted pursuant to the 2010 Incentive Award Plan. Option shall vest 7/48 one month after the date of grant and 1/48 each month thereafter.

SEC source: 0001280628-25-000004 · edgardoc.xml · nonDerivative · entry 4

GUTHART GARY S · CIK 0001280628 · Director · Executive Chair of the Board o

10b5-1 filing: Plan reported

Ownership: Indirect · Trust FBO Son

Disclosed balance after: 17,120

F1 · kind: The transaction took place in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on April 28, 2026.

F4 · price: The price reported in Column 4 is a weighted average sale price. These shares were sold in multiple transactions at prices ranging from $542.16 to $548.45 as follows: 190 shares sold at $542.16 to $542.98; 150 shares sold at $543.79 to $544.30; 190 shares sold at $545.00 to $545.33; 292 shares sold at $546.34 to $547.20; and 578 shares sold at $547.51 to $548.45. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

SEC source: 0001280628-25-000004 · edgardoc.xml · nonDerivative · entry 3

GUTHART GARY S · CIK 0001280628 · Director · Executive Chair of the Board o

10b5-1 filing: Plan reported

Ownership: Indirect · Trust FBO Daughter

Disclosed balance after: 17,120

F1 · kind: The transaction took place in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on April 28, 2026.

F3 · price: The price reported in Column 4 is a weighted average sale price. These shares were sold in multiple transactions at prices ranging from $542.74 to $548.48 as follows: 100 shares sold at $542.74; 205 shares sold at $543.97 to $544.45; 250 shares sold at $545.06 to $545.94; 200 shares sold at $546.46 to $546.75; and 645 shares sold at $547.49 to $548.48. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

SEC source: 0001280628-25-000004 · edgardoc.xml · nonDerivative · entry 2

GUTHART GARY S · CIK 0001280628 · Director · Executive Chair of the Board o

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 27,027

F1 · kind: The transaction took place in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on April 28, 2026.

F2 · price: The price reported in Column 4 is a weighted average sale price. These shares were sold in multiple transactions at prices ranging from $541.76 to $550.16 as follows: 800 shares sold at $541.76 to $542.59; 1,000 shares sold at $542.89 to $543.22; 2,563 shares sold at $544 to $545; 1,600 shares sold at $545.33 to $546.29; 2,770 shares sold at $546.34 to $547.19; 7,383 shares sold at $547.35 to $548.31; 9,068 shares sold at $548.36 to $549.35; and 3,616 shares sold at $549.485 to $550.16. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

SEC source: 0001280628-25-000004 · edgardoc.xml · nonDerivative · entry 1

GUTHART GARY S · CIK 0001280628 · Director · Executive Chair of the Board o

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 55,827

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transaction took place in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on April 28, 2026.

SEC source: 0001035267-25-000201 · edgardoc.xml · derivative · entry 6

GUTHART GARY S · CIK 0001280628 · Director · Executive Chair of the Board o

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 36,000 shares

Expires 2027-02-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transaction took place in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on April 28, 2026.

F3 · derivative.exercise_date: Non-statutory stock option granted pursuant to the 2010 Incentive Award Plan. The option vests 1/8th six months after the date of grant and 1/48th monthly thereafter.

SEC source: 0001035267-25-000201 · edgardoc.xml · nonDerivative · entry 2

GUTHART GARY S · CIK 0001280628 · Director · Executive Chair of the Board o

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 19,827

F1 · kind: The transaction took place in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on April 28, 2026.

F2 · price: The price reported in Column 4 is a weighted average sale price. These shares were sold in multiple transactions at prices ranging from $469.04 to $475.40 as follows: 5,200 shares sold at $469.04 to $470.03; 3,440 shares sold at $470.21 to $471.17; 4,400 shares sold at $471.38 to $472.38; 6,194 shares sold at $472.64 to $473.60; 7,921 shares sold at $473.79 to $474.72; and 2,205 shares sold at $475.00 to $475.40. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

SEC source: 0001035267-25-000201 · edgardoc.xml · nonDerivative · entry 1

GUTHART GARY S · CIK 0001280628 · Director · Executive Chair of the Board o

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 49,187

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transaction took place in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on April 28, 2026.

SEC source: 0001035267-25-000198 · edgardoc.xml · derivative · entry 6

GUTHART GARY S · CIK 0001280628 · Director · Executive Chair of the Board o

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 7,893 shares

Expires 2026-02-16

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transaction took place in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on April 28, 2026.

F6 · derivative.exercise_date: Non-statutory stock option granted pursuant to the 2010 Incentive Award Plan. The option vests 1/8th six months after the date of grant and 1/48th monthly thereafter.

SEC source: 0001035267-25-000198 · edgardoc.xml · nonDerivative · entry 5

GUTHART GARY S · CIK 0001280628 · Director · Executive Chair of the Board o

10b5-1 filing: Plan reported

Ownership: Indirect · by Trust

Disclosed balance after: 1,204,863

F5 · kind: The shares were donated to a Donor Advised Fund (DAF) in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on April 28, 2026.

SEC source: 0001035267-25-000198 · edgardoc.xml · nonDerivative · entry 4

GUTHART GARY S · CIK 0001280628 · Director · Executive Chair of the Board o

10b5-1 filing: Plan reported

Ownership: Indirect · Trust FBO Son

Disclosed balance after: 18,520

F1 · kind: The transaction took place in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on April 28, 2026.

F4 · price: The price reported in Column 4 is a weighted average sale price. These shares were sold in multiple transactions at prices ranging from $493.85 to $496.31 as follows: 320 shares sold at $493.85 to $494.85; 806 shares sold at $494.87 to $495.62; and 274 shares sold at $496.00 to $496.31. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

SEC source: 0001035267-25-000198 · edgardoc.xml · nonDerivative · entry 3

GUTHART GARY S · CIK 0001280628 · Director · Executive Chair of the Board o

10b5-1 filing: Plan reported

Ownership: Indirect · Trust FBO Daughter

Disclosed balance after: 18,520

F1 · kind: The transaction took place in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on April 28, 2026.

F3 · price: The price reported in Column 4 is a weighted average sale price. These shares were sold in multiple transactions at prices ranging from $493.85 to $496.31 as follows: 527 shares sold at $493.85 to $494.81; 569 shares sold at $494.97 to $495.72; and 304 shares sold at $496.00 to $496.31. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

SEC source: 0001035267-25-000198 · edgardoc.xml · nonDerivative · entry 2

GUTHART GARY S · CIK 0001280628 · Director · Executive Chair of the Board o

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 13,187

F1 · kind: The transaction took place in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on April 28, 2026.

F2 · price: The price reported in Column 4 is a weighted average sale price. These shares were sold in multiple transactions at prices ranging from $494.33 to $500.00 as follows: 475 shares sold at $494.33 to $495.16; 202 shares sold at $495.79 to $496.62; 1,045 shares sold at $496.81 to $496.87; 1,996 shares sold at $498.06 to $499.00; and 4,175 shares sold at $499.20 to $500.00. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

SEC source: 0001035267-25-000198 · edgardoc.xml · nonDerivative · entry 1

GUTHART GARY S · CIK 0001280628 · Director · Executive Chair of the Board o

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 21,080

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transaction took place in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on April 28, 2026.

SEC source: 0001127602-25-015508 · form4.xml · nonDerivative · entry 1

GUTHART GARY S · CIK 0001280628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,430

F1 · shares: Grant of restricted stock units. 100% of the shares subject to the restricted stock unit award shall vest on the earlier of (i) the one year anniversary of the date of grant of the award and (ii) the date immediately preceding the date of the annual meeting of the company's stockholders for the year following the year of grant of the award, provided, in each case, that the awardee continues to serve as a director on such date.

F2 · balance_after: In connection with Illumina's spin out of Grail, Inc., which was completed on June 24, 2024, all unvested equity award units were adjusted pursuant to Illumina's Amended and Restated 2015 Stock and Incentive Plan. Dr. Guthart's unvested RSUs were increased by 53 units as a result of such adjustment.

SEC source: 0001035267-25-000066 · edgardoc.xml · derivative · entry 8

GUTHART GARY S · CIK 0001280628 · Director · CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,506

Underlying: Common Stock · 2,506 shares

Expires 2026-02-28

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: Each RSU granted represents a contingent right to receive one share of Intuitive Surgical common stock. The grant vests 25% on the first anniversary of the date of grant and annually thereafter, over a four year period.

SEC source: 0001035267-25-000066 · edgardoc.xml · nonDerivative · entry 4

GUTHART GARY S · CIK 0001280628 · Director · CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 13,187

F3 · kind: This transaction represents the withholding of shares to cover taxes applicable to a settlement of PSUs reported on this Form 4.

SEC source: 0001035267-25-000066 · edgardoc.xml · nonDerivative · entry 3

GUTHART GARY S · CIK 0001280628 · Director · CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 19,400

F2 · kind: RSUs vest 25% per year over a four year period, commencing on the first anniversary of the grant date. RSUs convert into common stock on the vest date on a one-for-one basis. 25 % of the shares have been released and a portion of the shares were held back to cover the statutory tax withholding requirements. The net shares were deposited into the holders account.

SEC source: 0001035267-25-000066 · edgardoc.xml · nonDerivative · entry 2

GUTHART GARY S · CIK 0001280628 · Director · CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 20,643

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · kind: RSUs vest 25% per year over a four year period, commencing on the first anniversary of the grant date. RSUs convert into common stock on the vest date on a one-for-one basis. 25 % of the shares have been released and a portion of the shares were held back to cover the statutory tax withholding requirements. The net shares were deposited into the holders account.

SEC source: 0001035267-25-000066 · edgardoc.xml · nonDerivative · entry 1

GUTHART GARY S · CIK 0001280628 · Director · CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,137

F1 · kind: This transaction represents the certification of the performance goals under performance stock units ("PSUs").

SEC source: 0001035267-25-000044 · edgardoc.xml · derivative · entry 10

GUTHART GARY S · CIK 0001280628 · Director · CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 13,732

Underlying: Common Stock · 13,732 shares

Expires not disclosed

F2 · derivative.exercise_date: Each RSU granted represents a contingent right to receive one share of Intuitive Surgical common stock. The grant vests 25% on the first anniversary of the date of grant and annually thereafter, over a four year period.

F2 · derivative.expiration_date: Each RSU granted represents a contingent right to receive one share of Intuitive Surgical common stock. The grant vests 25% on the first anniversary of the date of grant and annually thereafter, over a four year period.

SEC source: 0001035267-25-000044 · edgardoc.xml · derivative · entry 9

GUTHART GARY S · CIK 0001280628 · Director · CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,880

Underlying: Common Stock · 4,961 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Each RSU granted represents a contingent right to receive one share of Intuitive Surgical common stock. The grant vests 25% on the first anniversary of the date of grant and annually thereafter, over a four year period.

F2 · derivative.expiration_date: Each RSU granted represents a contingent right to receive one share of Intuitive Surgical common stock. The grant vests 25% on the first anniversary of the date of grant and annually thereafter, over a four year period.