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Nasdaq · USD

SYRE

Spyre Therapeutics, Inc.

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Tapewire entity
2649
SEC CIK
0001636282
Parsed reports
239

Last 12 months

Inside the activity.

0 purchase rows · 96 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202502
Dec 202502
Jan 202603
Feb 202602
Mar 202604
Apr 202605
May 2026018
Jun 2026011
Jul 202607
Aug 2026011
Sep 2026015
Oct 2026016

Latest available

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
February 06, 2019 Filed Feb 8, 2019 16:15 UTC
Quinn Anthony G.Director · President & CEO
Exercise / conversionCommon Stock 1,323 $5.46 $7,223.58
Disclosure

SEC source: 0001567619-19-002796 · doc1.xml · nonDerivative · entry 1

Quinn Anthony G. · CIK 0001532219 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 269,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
December 28, 2018 Filed Feb 14, 2022 17:19 UTC
Quinn Anthony G.Director · President & CEO
GiftCommon Stock 57,450 $0.00 $0.00
Disclosure

SEC source: 0001209191-22-009407 · doc5.xml · nonDerivative · entry 2

Quinn Anthony G. · CIK 0001532219 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 57,450

F1 · ownership.nature: These securities are held by the Anthony G. Quinn Irrevocable Trust of 2018, of which the Reporting Person's spouse is trustee.

Read SEC document
December 28, 2018 Filed Feb 14, 2022 17:19 UTC
Quinn Anthony G.Director · President & CEO
GiftCommon Stock 57,450 $0.00 $0.00
Disclosure

SEC source: 0001209191-22-009407 · doc5.xml · nonDerivative · entry 1

Quinn Anthony G. · CIK 0001532219 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 328,795

Read SEC document
December 07, 2018 Filed Dec 10, 2018 17:40 UTC
Quinn Anthony G.Director · President & CEO
Exercise / conversionDirector Stock Option (right to buy) · Derivative 18,584 $0.00 Strike: $6.31 $0.00
Disclosure

SEC source: 0001567619-18-007640 · doc1.xml · derivative · entry 8

Quinn Anthony G. · CIK 0001532219 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 144,950

Underlying: Common Stock · 18,584 shares

Expires 2028-02-19

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: The stock option vests and becomes exercisable in 48 equal monthly installments beginning on March 20, 2018, until such time as the option is 100% vested, subject to the continuing employment of the Reporting Person on each vesting date.

Read SEC document
December 07, 2018 Filed Dec 10, 2018 17:40 UTC
Quinn Anthony G.Director · President & CEO
Exercise / conversionDirector Stock Option (right to buy) · Derivative 3,306 $0.00 Strike: $5.46 $0.00
Disclosure

SEC source: 0001567619-18-007640 · doc1.xml · derivative · entry 7

Quinn Anthony G. · CIK 0001532219 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,985

Underlying: Common Stock · 3,306 shares

Expires 2026-03-17

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: The stock option vested and became exercisable as to 1/36th of the shares subject to the option on April 3, 2016, and thereafter vests as to 1/36th of the shares each month in equal installments, until such time as the option is 100% vested, subject to the continuing service of the Reporting Person on each vesting date.

Read SEC document
December 07, 2018 Filed Dec 10, 2018 17:40 UTC
Quinn Anthony G.Director · President & CEO
Exercise / conversionDirector Stock Option (right to buy) · Derivative 150,000 $0.00 Strike: $4.11 $0.00
Disclosure

SEC source: 0001567619-18-007640 · doc1.xml · derivative · entry 6

Quinn Anthony G. · CIK 0001532219 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 150,000 shares

Expires 2027-08-30

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The stock option vested and became exercisable as to 100% of the shares subject to the option on July 18, 2018, subject to the continuing service of the Reporting Person on the vesting date.

Read SEC document
December 07, 2018 Filed Dec 10, 2018 17:40 UTC
Quinn Anthony G.Director · President & CEO
Exercise / conversionCommon Stock 18,584 $6.31 $117,265.04
Disclosure

SEC source: 0001567619-18-007640 · doc1.xml · nonDerivative · entry 5

Quinn Anthony G. · CIK 0001532219 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 267,677

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
December 07, 2018 Filed Dec 10, 2018 17:40 UTC
Quinn Anthony G.Director · President & CEO
Exercise / conversionCommon Stock 3,306 $5.46 $18,050.76
Disclosure

SEC source: 0001567619-18-007640 · doc1.xml · nonDerivative · entry 4

Quinn Anthony G. · CIK 0001532219 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 249,093

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
December 07, 2018 Filed Dec 10, 2018 17:40 UTC
Quinn Anthony G.Director · President & CEO
Exercise / conversionCommon Stock 150,000 $4.11 $616,500.00
Disclosure

SEC source: 0001567619-18-007640 · doc1.xml · nonDerivative · entry 3

Quinn Anthony G. · CIK 0001532219 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 245,787

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
September 27, 2018 Filed Sep 28, 2018 17:11 UTC
Schuchart AaronChief Business Officer
SaleCommon Stock 5,900 $9.50 $56,050.00
Disclosure

SEC source: 0001567619-18-003282 · doc1.xml · nonDerivative · entry 2

Schuchart Aaron · CIK 0001709258 · Chief Business Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,500

Read SEC document
September 27, 2018 Filed Sep 28, 2018 17:11 UTC
Schuchart AaronChief Business Officer
SaleCommon Stock 100 $9.55 $955.00
Disclosure

SEC source: 0001567619-18-003282 · doc1.xml · nonDerivative · entry 1

Schuchart Aaron · CIK 0001709258 · Chief Business Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,400

Read SEC document
August 17, 2018 Filed Aug 21, 2018 16:24 UTC
Schuchart AaronChief Business Officer
Exercise / conversionEmployee Stock Option (right to buy) · Derivative 8,500 $0.00 Strike: $3.50 $0.00
Disclosure

SEC source: 0001567619-18-001566 · doc1.xml · derivative · entry 2

Schuchart Aaron · CIK 0001709258 · Chief Business Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 91,500

Underlying: Common Stock · 8,500 shares

Expires 2027-06-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: The stock option vested and became exercisable as to 1/4th of the shares subject to the option on May 22, 2018, and thereafter vests and becomes exercisable as to 1/48th of the shares in equal monthly installments, until such time as the option is 100% vested, subject to the continuing employment of the Reporting Person on each vesting date.

Read SEC document
August 17, 2018 Filed Aug 21, 2018 16:24 UTC
Schuchart AaronChief Business Officer
Exercise / conversionCommon Stock 8,500 $3.50 $29,750.00
Disclosure

SEC source: 0001567619-18-001566 · doc1.xml · nonDerivative · entry 1

Schuchart Aaron · CIK 0001709258 · Chief Business Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,500

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
August 15, 2018 Filed Dec 10, 2018 17:40 UTC
Quinn Anthony G.Director · President & CEO
PurchaseCommon Stock 994 $9.13 $9,075.22
Disclosure

SEC source: 0001567619-18-007640 · doc1.xml · nonDerivative · entry 2

Quinn Anthony G. · CIK 0001532219 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 95,787

F1 · shares: These shares were acquired under the Issuer's Employee Stock Purchase Plan in a transaction that was exempt under both Rule 16b-3(d) and Rule 16b-3(c).

Read SEC document
August 13, 2018 Filed Aug 15, 2018 16:40 UTC Exercise / conversionDirector Stock Option (right to buy) · Derivative 20,000 $0.00 Strike: $4.73 $0.00
Disclosure

SEC source: 0001567619-18-001186 · doc1.xml · derivative · entry 4

GEORGIOU GEORGE · CIK 0000749811 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Common Stock · 20,000 shares

Expires 2027-11-30

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The stock option vested and became exercisable, and shall continue to vest and become exercisable, in 12 equal monthly installments beginning on January 1, 2018 until such time as the option is 100% vested, subject to the continuing service of the Reporting Person on each vesting date.

Read SEC document
August 13, 2018 Filed Aug 15, 2018 16:40 UTC Exercise / conversionDirector Stock Option (right to buy) · Derivative 17,333 $0.00 Strike: $7.28 $0.00
Disclosure

SEC source: 0001567619-18-001186 · doc1.xml · derivative · entry 3

GEORGIOU GEORGE · CIK 0000749811 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,667

Underlying: Common Stock · 17,333 shares

Expires 2026-05-16

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: The stock option vested and became exercisable, and shall continue to vest and become exercisable, in 36 equal monthly installments beginning on June 17, 2016, until such time as the option is 100% vested, subject to the continuing service of the Reporting Person on each vesting date.

Read SEC document
August 13, 2018 Filed Aug 15, 2018 16:40 UTC Exercise / conversionCommon Stock 20,000 $4.73 $94,600.00
Disclosure

SEC source: 0001567619-18-001186 · doc1.xml · nonDerivative · entry 2

GEORGIOU GEORGE · CIK 0000749811 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 175,861

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
August 13, 2018 Filed Aug 15, 2018 16:40 UTC Exercise / conversionCommon Stock 17,333 $7.28 $126,184.24
Disclosure

SEC source: 0001567619-18-001186 · doc1.xml · nonDerivative · entry 1

GEORGIOU GEORGE · CIK 0000749811 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 155,861

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
July 18, 2018 Filed Jul 20, 2018 17:26 UTC
Quinn Anthony G.Director · President & CEO
GrantEmployee Stock Option (right to buy) · Derivative 50,000 $0.00 Strike: $9.36 $0.00
Disclosure

SEC source: 0001140361-18-033053 · doc1.xml · derivative · entry 4

Quinn Anthony G. · CIK 0001532219 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 50,000

Underlying: Common Stock · 50,000 shares

Expires 2028-07-17

F4 · derivative.exercise_date: The stock option vests and becomes exercisable contingent upon achievement of certain regulatory milestones.

Read SEC document
July 18, 2018 Filed Jul 20, 2018 17:26 UTC
Quinn Anthony G.Director · President & CEO
GrantEmployee Stock Option (right to buy) · Derivative 75,000 $0.00 Strike: $9.36 $0.00
Disclosure

SEC source: 0001140361-18-033053 · doc1.xml · derivative · entry 3

Quinn Anthony G. · CIK 0001532219 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 75,000

Underlying: Common Stock · 75,000 shares

Expires 2028-07-17

F3 · derivative.exercise_date: The stock option vests and becomes exercisable contingent upon achievement of certain product development milestones.

Read SEC document
July 18, 2018 Filed Jul 20, 2018 17:26 UTC
Quinn Anthony G.Director · President & CEO
GrantEmployee Stock Option (right to buy) · Derivative 75,000 $0.00 Strike: $9.36 $0.00
Disclosure

SEC source: 0001140361-18-033053 · doc1.xml · derivative · entry 2

Quinn Anthony G. · CIK 0001532219 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 75,000

Underlying: Common Stock · 75,000 shares

Expires 2028-07-17

F2 · derivative.exercise_date: The stock option vests and becomes exercisable contingent upon achievement of certain stock price milestones.

Read SEC document
July 18, 2018 Filed Jul 20, 2018 17:26 UTC
Quinn Anthony G.Director · President & CEO
GrantEmployee Stock Option (right to buy) · Derivative 300,000 $0.00 Strike: $9.36 $0.00
Disclosure

SEC source: 0001140361-18-033053 · doc1.xml · derivative · entry 1

Quinn Anthony G. · CIK 0001532219 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 300,000

Underlying: Common Stock · 300,000 shares

Expires 2028-07-17

F1 · derivative.exercise_date: The stock option vests and becomes exercisable in 48 equal monthly installments beginning on August 18, 2018, until such time as the option is 100% vested, subject to the continuing employment of the Reporting Person on each vesting date.

Read SEC document
July 13, 2018 Filed Jul 17, 2018 16:27 UTC GrantDirector Stock Option (right to buy) · Derivative 36,800 $0.00 Strike: $8.78 $0.00
Disclosure

SEC source: 0001140361-18-032716 · doc1.xml · derivative · entry 1

LAWLIS V BRYAN · CIK 0001247681 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,800

Underlying: Common Stock · 36,800 shares

Expires 2028-07-12

F1 · derivative.exercise_date: The stock option vests and becomes exercisable in 36 equal monthly installments beginning on August 13, 2018, until such time as the option is 100% vested, subject to the continuing service of the Reporting Person on each vesting date.

Read SEC document
July 12, 2018 Filed Jul 16, 2018 09:04 UTC
Quinn Anthony G.Director · Interim CEO
Exercise / conversionDirector Stock Option (right to buy) · Derivative 14,866 $0.00 Strike: $6.31 $0.00
Disclosure

SEC source: 0001140361-18-032462 · doc1.xml · derivative · entry 4

Quinn Anthony G. · CIK 0001532219 · Director · Interim CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 163,534

Underlying: Common Stock · 14,866 shares

Expires 2028-02-19

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The stock option vests and becomes exercisable in 48 equal monthly installments beginning on March 20, 2018, until such time as the option is 100% vested, subject to the continuing employment of the Reporting Person on each vesting date.

Read SEC document
July 12, 2018 Filed Jul 16, 2018 09:04 UTC
Quinn Anthony G.Director · Interim CEO
Exercise / conversionDirector Stock Option (right to buy) · Derivative 24,000 $0.00 Strike: $7.04 $0.00
Disclosure

SEC source: 0001140361-18-032462 · doc1.xml · derivative · entry 3

Quinn Anthony G. · CIK 0001532219 · Director · Interim CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 24,000 shares

Expires 2027-04-20

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: The stock option is fully vested and immediately exercisable.

Read SEC document
July 12, 2018 Filed Jul 16, 2018 09:04 UTC
Quinn Anthony G.Director · Interim CEO
Exercise / conversionCommon Stock 14,866 $6.31 $93,804.46
Disclosure

SEC source: 0001140361-18-032462 · doc1.xml · nonDerivative · entry 2

Quinn Anthony G. · CIK 0001532219 · Director · Interim CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 92,793

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
July 12, 2018 Filed Jul 16, 2018 09:04 UTC
Quinn Anthony G.Director · Interim CEO
Exercise / conversionCommon Stock 24,000 $7.04 $168,960.00
Disclosure

SEC source: 0001140361-18-032462 · doc1.xml · nonDerivative · entry 1

Quinn Anthony G. · CIK 0001532219 · Director · Interim CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 77,927

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
July 11, 2018 Filed Jul 13, 2018 09:05 UTC
Quinn Anthony G.Director · Interim CEO
Exercise / conversionDirector Stock Option (right to buy) · Derivative 3,307 $0.00 Strike: $5.46 $0.00
Disclosure

SEC source: 0001140361-18-032316 · doc1.xml · derivative · entry 2

Quinn Anthony G. · CIK 0001532219 · Director · Interim CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,291

Underlying: Common Stock · 3,307 shares

Expires 2026-03-17

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: The stock option vested and became exercisable as to 1/36th of the shares subject to the option on April 3, 2016, and thereafter vests as to 1/36th of the shares each month in equal installments, until such time as the option is 100% vested, subject to the continuing service of the Reporting Person on each vesting date.

Read SEC document
July 11, 2018 Filed Jul 13, 2018 09:05 UTC
Quinn Anthony G.Director · Interim CEO
Exercise / conversionCommon Stock 3,307 $5.46 $18,056.22
Disclosure

SEC source: 0001140361-18-032316 · doc1.xml · nonDerivative · entry 1

Quinn Anthony G. · CIK 0001532219 · Director · Interim CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 53,927

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 07, 2018 Filed Jun 8, 2018 18:44 UTC GrantDirector Stock Option (right to buy) · Derivative 18,400 $0.00 Strike: $10.28 $0.00
Disclosure

SEC source: 0001140361-18-027928 · doc1.xml · derivative · entry 1

GEORGIOU GEORGE · CIK 0000749811 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,400

Underlying: Common Stock · 18,400 shares

Expires 2028-06-06

F1 · derivative.exercise_date: The stock option vests and becomes exercisable in 12 equal monthly installments beginning on July 7, 2018 until such time as the option is 100% vested, subject to the continuing service of the Reporting Person on each vesting date.

Read SEC document
June 07, 2018 Filed Jun 8, 2018 18:47 UTC
Shanafelt ArmenDirector · 10% owner
GrantDirector Stock Option (right to buy) · Derivative 18,400 $0.00 Strike: $10.28 $0.00
Disclosure

SEC source: 0001140361-18-027931 · doc1.xml · derivative · entry 1

Shanafelt Armen · CIK 0001656151 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,400

Underlying: Common Stock · 18,400 shares

Expires 2028-06-06

F1 · derivative.exercise_date: The stock option vests and becomes exercisable in 12 equal monthly installments beginning on July 7, 2018 until such time as the option is 100% vested, subject to the continuing service of the Reporting Person on each vesting date.

Read SEC document
June 07, 2018 Filed Jun 8, 2018 22:45 UTC GrantDirector Stock Option (right to buy) · Derivative 18,400 $0.00 Strike: $10.28 $0.00
Disclosure

SEC source: 0001140361-18-027929 · doc1.xml · derivative · entry 1

Mahatme Sandesh · CIK 0001511034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,400

Underlying: Common Stock · 18,400 shares

Expires 2028-06-06

F1 · derivative.exercise_date: The stock option vests and becomes exercisable in 12 equal monthly installments beginning on July 7, 2018 until such time as the option is 100% vested, subject to the continuing service of the Reporting Person on each vesting date.

Read SEC document
June 07, 2018 Filed Jun 8, 2018 22:43 UTC GrantDirector Stock Option (right to buy) · Derivative 18,400 $0.00 Strike: $10.28 $0.00
Disclosure

SEC source: 0001140361-18-027927 · doc1.xml · derivative · entry 1

Cox Russell J. · CIK 0001512984 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,400

Underlying: Common Stock · 18,400 shares

Expires 2028-06-06

F1 · derivative.exercise_date: The stock option vests and becomes exercisable in 12 equal monthly installments beginning on July 7, 2018 until such time as the option is 100% vested, subject to the continuing service of the Reporting Person on each vesting date.

Read SEC document
June 07, 2018 Filed Jun 8, 2018 22:42 UTC GrantDirector Stock Option (right to buy) · Derivative 18,400 $0.00 Strike: $10.28 $0.00
Disclosure

SEC source: 0001140361-18-027926 · doc1.xml · derivative · entry 1

Bruhn Suzanne Louise · CIK 0001517790 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,400

Underlying: Common Stock · 18,400 shares

Expires 2028-06-06

F1 · derivative.exercise_date: The stock option vests and becomes exercisable in 12 equal monthly installments beginning on July 7, 2018 until such time as the option is 100% vested, subject to the continuing service of the Reporting Person on each vesting date.

Read SEC document
May 11, 2018 Filed May 14, 2018 20:01 UTC
NOVARTIS AG10% owner
SaleCommon Stock 19,550 $10.06 $196,673.00
Disclosure

SEC source: 0001140361-18-023310 · form4.xml · nonDerivative · entry 1

Novartis Bioventures Ltd · CIK 0001297709 · 10% owner

NOVARTIS AG · CIK 0001114448 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,175,314

F1 · price: Reflects sales of common stock executed in multiple transactions at prices ranging from $10.00 to $10.25. The price reported reflects the weighted average sale price. The Reporting Persons hereby undertake to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected.

F2 · ownership.direct: The shares are directly owned by Novartis Bioventures Ltd. Novartis Bioventures Ltd. is a wholly-owned indirect subsidiary of Novartis AG, which is an indirect beneficial owner of the reported securities.

Read SEC document
May 10, 2018 Filed May 11, 2018 20:28 UTC
NOVARTIS AG10% owner
SaleCommon Stock 22,725 $10.13 $230,204.25
Disclosure

SEC source: 0001140361-18-023060 · form4.xml · nonDerivative · entry 2

Novartis Bioventures Ltd · CIK 0001297709 · 10% owner

NOVARTIS AG · CIK 0001114448 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,194,864

F3 · price: Reflects sales of common stock executed in multiple transactions at prices ranging from $10.00 to $10.34. The price reported reflects the weighted average sale price. The Reporting Persons hereby undertake to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected.

F2 · ownership.direct: The shares are directly owned by Novartis Bioventures Ltd. Novartis Bioventures Ltd. is a wholly-owned indirect subsidiary of Novartis AG, which is an indirect beneficial owner of the reported securities.

Read SEC document
May 09, 2018 Filed May 11, 2018 20:28 UTC
NOVARTIS AG10% owner
SaleCommon Stock 51,230 $10.11 $517,935.30
Disclosure

SEC source: 0001140361-18-023060 · form4.xml · nonDerivative · entry 1

Novartis Bioventures Ltd · CIK 0001297709 · 10% owner

NOVARTIS AG · CIK 0001114448 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,217,589

F1 · price: Reflects sales of common stock executed in multiple transactions at prices ranging from $10.00 to $10.48. The price reported reflects the weighted average sale price. The Reporting Persons hereby undertake to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected.

F2 · ownership.direct: The shares are directly owned by Novartis Bioventures Ltd. Novartis Bioventures Ltd. is a wholly-owned indirect subsidiary of Novartis AG, which is an indirect beneficial owner of the reported securities.

Read SEC document
May 08, 2018 Filed May 9, 2018 20:01 UTC
NOVARTIS AG10% owner
SaleCommon Stock 26,557 $10.03 $266,366.71
Disclosure

SEC source: 0001140361-18-022477 · form4.xml · nonDerivative · entry 2

Novartis Bioventures Ltd · CIK 0001297709 · 10% owner

NOVARTIS AG · CIK 0001114448 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,268,819

F3 · price: Reflects sales of common stock executed in multiple transactions at prices ranging from $10.00 to $10.12. The price reported reflects the weighted average sale price. The Reporting Persons hereby undertake to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected.

F2 · ownership.direct: The shares are directly owned by Novartis Bioventures Ltd. Novartis Bioventures Ltd. is a wholly-owned indirect subsidiary of Novartis AG, which is an indirect beneficial owner of the reported securities.

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May 07, 2018 Filed May 9, 2018 20:01 UTC
NOVARTIS AG10% owner
SaleCommon Stock 15,548 $10.11 $157,190.28
Disclosure

SEC source: 0001140361-18-022477 · form4.xml · nonDerivative · entry 1

Novartis Bioventures Ltd · CIK 0001297709 · 10% owner

NOVARTIS AG · CIK 0001114448 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,295,376

F1 · price: Reflects sales of common stock executed in multiple transactions at prices ranging from $10.00 to $10.33. The price reported reflects the weighted average sale price. The Reporting Persons hereby undertake to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected.

F2 · ownership.direct: The shares are directly owned by Novartis Bioventures Ltd. Novartis Bioventures Ltd. is a wholly-owned indirect subsidiary of Novartis AG, which is an indirect beneficial owner of the reported securities.

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March 22, 2018 Filed Mar 26, 2018 12:05 UTC GrantDirector Stock Option (right to buy) · Derivative 36,800 $0.00 Strike: $10.50 $0.00
Disclosure

SEC source: 0001140361-18-014889 · doc1.xml · derivative · entry 1

Magovcevic Ivana · CIK 0001279281 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,800

Underlying: Common Stock · 36,800 shares

Expires 2028-03-21

F1 · derivative.exercise_date: The stock option vests and becomes exercisable in 36 equal monthly installments beginning on April 22, 2018, until such time as the option is 100% vested, subject to the continuing service of the Reporting Person on each vesting date.

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February 20, 2018 Filed Feb 22, 2018 18:25 UTC
Wooldridge JamesChief Medical Officer
GrantEmployee Stock Option (right to buy) · Derivative 45,000 $0.00 Strike: $6.31 $0.00
Disclosure

SEC source: 0001140361-18-009668 · doc1.xml · derivative · entry 1

Wooldridge James · CIK 0001710641 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,000

Underlying: Common Stock · 45,000 shares

Expires 2028-02-19

F1 · derivative.exercise_date: The stock option vests and becomes exercisable in 48 equal monthly installments beginning on March 20, 2018, until such time as the option is 100% vested, subject to the continuing employment of the Reporting Person on each vesting date.

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February 20, 2018 Filed Feb 22, 2018 18:22 UTC
Schuchart AaronChief Business Officer
GrantEmployee Stock Option (right to buy) · Derivative 20,000 $0.00 Strike: $6.31 $0.00
Disclosure

SEC source: 0001140361-18-009664 · doc1.xml · derivative · entry 1

Schuchart Aaron · CIK 0001709258 · Chief Business Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,000

Underlying: Common Stock · 20,000 shares

Expires 2028-02-19

F1 · derivative.exercise_date: The stock option vests and becomes exercisable in 48 equal monthly installments beginning on March 20, 2018, until such time as the option is 100% vested, subject to the continuing employment of the Reporting Person on each vesting date.

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February 20, 2018 Filed Feb 22, 2018 18:23 UTC
Quinn Anthony G.Director · Interim CEO
GrantEmployee Stock Option (right to buy) · Derivative 178,400 $0.00 Strike: $6.31 $0.00
Disclosure

SEC source: 0001140361-18-009665 · doc1.xml · derivative · entry 1

Quinn Anthony G. · CIK 0001532219 · Director · Interim CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 178,400

Underlying: Common Stock · 178,400 shares

Expires 2028-02-19

F1 · derivative.exercise_date: The stock option vests and becomes exercisable in 48 equal monthly installments beginning on March 20, 2018, until such time as the option is 100% vested, subject to the continuing employment of the Reporting Person on each vesting date.

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February 20, 2018 Filed Feb 22, 2018 23:24 UTC
York Charles N IIChief Financial Officer and VP
GrantEmployee Stock Option (right to buy) · Derivative 92,100 $0.00 Strike: $6.31 $0.00
Disclosure

SEC source: 0001140361-18-009666 · doc1.xml · derivative · entry 1

York Charles N II · CIK 0001655962 · Chief Financial Officer and VP

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 92,100

Underlying: Common Stock · 92,100 shares

Expires 2028-02-19

F1 · derivative.exercise_date: The stock option vests and becomes exercisable in 48 equal monthly installments beginning on March 20, 2018, until such time as the option is 100% vested, subject to the continuing employment of the Reporting Person on each vesting date.

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February 15, 2018 Filed Feb 20, 2018 16:36 UTC
Quinn Anthony G.Director · Interim CEO
Exercise / conversionDirector Stock Option (right to buy) · Derivative 15,211 $0.00 Strike: $5.46 $0.00
Disclosure

SEC source: 0001140361-18-009074 · doc1.xml · derivative · entry 2

Quinn Anthony G. · CIK 0001532219 · Director · Interim CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,598

Underlying: Common Stock · 15,211 shares

Expires 2026-03-17

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: The stock option vested and became exercisable as to 1/36th of the shares subject to the option on April 3, 2016, and thereafter vests as to 1/36th of the shares each month in equal installments, until such time as the option is 100% vested, subject to the continuing service of the Reporting Person on each vesting date.

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February 15, 2018 Filed Feb 20, 2018 16:36 UTC
Quinn Anthony G.Director · Interim CEO
Exercise / conversionCommon Stock 15,211 $5.46 $83,052.06
Disclosure

SEC source: 0001140361-18-009074 · doc1.xml · nonDerivative · entry 1

Quinn Anthony G. · CIK 0001532219 · Director · Interim CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 50,620

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

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February 15, 2018 Filed Dec 10, 2018 17:40 UTC
Quinn Anthony G.Director · President & CEO
PurchaseCommon Stock 2,000 $6.02 $12,040.00
Disclosure

SEC source: 0001567619-18-007640 · doc1.xml · nonDerivative · entry 1

Quinn Anthony G. · CIK 0001532219 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 94,793

F1 · shares: These shares were acquired under the Issuer's Employee Stock Purchase Plan in a transaction that was exempt under both Rule 16b-3(d) and Rule 16b-3(c).

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December 08, 2017 Filed Dec 8, 2017 19:06 UTC
Quinn Anthony G.Director · Interim CEO
PurchaseCommon Stock 600 $5.07 $3,039.00
Disclosure

SEC source: 0001140361-17-045528 · doc1.xml · nonDerivative · entry 3

Quinn Anthony G. · CIK 0001532219 · Director · Interim CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 35,409

F3 · price: Represents a weighted average purchase price per share. These shares were purchased in multiple transactions at prices ranging from $5.01 to $5.10 per share. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares purchased at each separate price within the range.

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December 07, 2017 Filed Dec 8, 2017 19:06 UTC
Quinn Anthony G.Director · Interim CEO
PurchaseCommon Stock 2,800 $4.99 $13,966.96
Disclosure

SEC source: 0001140361-17-045528 · doc1.xml · nonDerivative · entry 2

Quinn Anthony G. · CIK 0001532219 · Director · Interim CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,809

F2 · price: Represents a weighted average purchase price per share. These shares were purchased in multiple transactions at prices ranging from $4.88 to $5.10 per share. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares purchased at each separate price within the range.

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December 06, 2017 Filed Dec 8, 2017 19:06 UTC
Quinn Anthony G.Director · Interim CEO
PurchaseCommon Stock 4,888 $4.92 $24,072.42
Disclosure

SEC source: 0001140361-17-045528 · doc1.xml · nonDerivative · entry 1

Quinn Anthony G. · CIK 0001532219 · Director · Interim CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,009

F1 · price: Represents a weighted average purchase price per share. These shares were purchased in multiple transactions at prices ranging from $4.77 to $5.05 per share. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares purchased at each separate price within the range.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.