SRZN

SEC source: 0001193125-26-316570 · ownership.xml · nonDerivative · entry 2

TCG Crossover GP II, LLC · CIK 0001969280 · 10% owner

TCG Crossover Fund II, L.P. · CIK 0001969281 · 10% owner

TCG Crossover GP III, LLC · CIK 0002062816 · 10% owner

TCG Crossover Fund III, L.P. · CIK 0002062644 · 10% owner

Yu Chen-Ming · CIK 0001517933 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnote

Disclosed balance after: 574,047

F1 · kind: As of the date of this filing, the Reporting Persons have disgorged to the Issuer the full amount of the short-swing profits realized from the sales reported herein, as required by Section 16(b) of the Securities Exchange Act of 1934

F3 · ownership.nature: These securities are held of record by TCG Crossover Fund III, L.P. (TCG Crossover III). TCG Crossover GP III, LLC (TCG Crossover GP III) is the general partner of TCG Crossover III and may be deemed to have voting, investment, and dispositive power with respect to these securities. Chen Yu is the sole managing member of TCG Crossover GP III and may be deemed to share voting, investment and dispositive power with respect to these securities.

SEC source: 0001193125-26-316570 · ownership.xml · nonDerivative · entry 1

TCG Crossover GP II, LLC · CIK 0001969280 · 10% owner

TCG Crossover Fund II, L.P. · CIK 0001969281 · 10% owner

TCG Crossover GP III, LLC · CIK 0002062816 · 10% owner

TCG Crossover Fund III, L.P. · CIK 0002062644 · 10% owner

Yu Chen-Ming · CIK 0001517933 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnote

Disclosed balance after: 574,054

F1 · kind: As of the date of this filing, the Reporting Persons have disgorged to the Issuer the full amount of the short-swing profits realized from the sales reported herein, as required by Section 16(b) of the Securities Exchange Act of 1934

F2 · ownership.nature: These securities are held of record by TCG Crossover Fund II, L.P. (TCG Crossover II). TCG Crossover GP II, LLC (TCG Crossover GP II) is the general partner of TCG Crossover II and may be deemed to have voting, investment, and dispositive power with respect to these securities. Chen Yu is the sole managing member of TCG Crossover GP II and may be deemed to share voting, investment and dispositive power with respect to these securities.

SEC source: 0001193125-26-272796 · ownership.xml · nonDerivative · entry 1

Maleki Andrew Pedrum · CIK 0002096218 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 607

F1 · kind: This reporting person is voluntarily reporting these shares acquired under the Surrozen, Inc. 2021 Employee Stock Purchase Plan in transactions that were exempt under both Rule 16b-3(d) and Rule 16b-3(c).

SEC source: 0001193125-26-272765 · ownership.xml · nonDerivative · entry 1

Williams Charles O · CIK 0001325818 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,237

F1 · kind: This reporting person is voluntarily reporting these shares acquired under the Surrozen, Inc. 2021 Employee Stock Purchase Plan in transactions that were exempt under both Rule 16b-3(d) and Rule 16b-3(c).

SEC source: 0001193125-26-272754 · ownership.xml · nonDerivative · entry 1

Parker Craig C · CIK 0001526064 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,175

F1 · kind: This reporting person is voluntarily reporting these shares acquired under the Surrozen, Inc. 2021 Employee Stock Purchase Plan in transactions that were exempt under both Rule 16b-3(d) and Rule 16b-3(c).

SEC source: 0001193125-26-272780 · ownership.xml · nonDerivative · entry 1

Li Yang · CIK 0001990537 · Exec. Vice President, Research

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,882

F1 · kind: This reporting person is voluntarily reporting these shares acquired under the Surrozen, Inc. 2021 Employee Stock Purchase Plan in transactions that were exempt under both Rule 16b-3(d) and Rule 16b-3(c).

SEC source: 0001193125-26-224117 · ownership.xml · derivative · entry 1

Berkenblit Anna · CIK 0001691868 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,550

Underlying: Common Stock · 5,550 shares

Expires 2036-05-12

F1 · derivative.exercise_date: The options vest and become exercisable on the anniversary of the grant date, subject to continuous service as a director.

SEC source: 0001193125-26-224244 · ownership.xml · derivative · entry 1

WOODHOUSE DAVID J · CIK 0001642995 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,550

Underlying: Common Stock · 5,550 shares

Expires 2036-05-12

F1 · derivative.exercise_date: The options vest and become exercisable on the anniversary of the grant date, subject to continuous service as a director.

SEC source: 0001193125-26-224145 · ownership.xml · derivative · entry 1

CHAI CHRISTOPHER Y · CIK 0001413823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,550

Underlying: Common Stock · 5,550 shares

Expires 2036-05-12

F1 · derivative.exercise_date: The options vest and become exercisable on the anniversary of the grant date, subject to continuous service as a director.

SEC source: 0001193125-26-224131 · ownership.xml · derivative · entry 1

BJERKHOLT ERIC · CIK 0001197350 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,550

Underlying: Common Stock · 5,550 shares

Expires 2036-05-12

F1 · derivative.exercise_date: The options vest and become exercisable on the anniversary of the grant date, subject to continuous service as a director.

SEC source: 0001193125-26-224157 · ownership.xml · derivative · entry 1

Haak-Frendscho Mary · CIK 0001873902 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,550

Underlying: Common Stock · 5,550 shares

Expires 2036-05-12

F1 · derivative.exercise_date: The options vest and become exercisable on the anniversary of the grant date, subject to continuous service as a director.

SEC source: 0001193125-26-224286 · ownership.xml · derivative · entry 1

Rothenberg Mace · CIK 0001873988 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,550

Underlying: Common Stock · 5,550 shares

Expires 2036-05-12

F1 · derivative.exercise_date: The options vest and become exercisable on the anniversary of the grant date, subject to continuous service as a director.

SEC source: 0001193125-26-230953 · ownership.xml · derivative · entry 1

Kutzkey Tim · CIK 0001614186 · Director · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,550

Underlying: Common Stock · 5,550 shares

Expires 2036-05-12

F1 · derivative.exercise_date: The options vest and become exercisable on the anniversary of the grant date, subject to Reporting Person's continuous service as a member of the Board of Directors of the Issuer.

SEC source: 0001193125-26-206679 · ownership.xml · nonDerivative · entry 2

Williams Charles O · CIK 0001325818 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,571

F2 · price: The shares were sold to cover withholding taxes upon vesting of RSUs in transactions that were initiated by the Issuer on the reporting person's behalf. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $33.04 to $33.63, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0001193125-26-206658 · ownership.xml · nonDerivative · entry 2

Parker Craig C · CIK 0001526064 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,553

F2 · price: The shares were sold to cover withholding taxes upon vesting of RSUs in transactions that were initiated by the Issuer on the reporting person's behalf. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $33.04 to $33.63, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0001193125-26-206695 · ownership.xml · nonDerivative · entry 2

Li Yang · CIK 0001990537 · Exec. Vice President, Research

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 17,216

F2 · price: The shares were sold to cover withholding taxes upon vesting of RSUs in transactions that were initiated by the Issuer on the reporting person's behalf. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $33.04 to $33.63, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0001193125-26-206679 · ownership.xml · derivative · entry 3

Williams Charles O · CIK 0001325818 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,625

Underlying: Common Stock · 5,625 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit, or RSU, represents a contingent right to receive one share of the Issuer's common stock.

F3 · derivative.exercise_date: These RSUs vest in two equal installments on May 1, 2026 and May 1, 2027.

F3 · derivative.expiration_date: These RSUs vest in two equal installments on May 1, 2026 and May 1, 2027.

SEC source: 0001193125-26-206679 · ownership.xml · nonDerivative · entry 1

Williams Charles O · CIK 0001325818 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,607

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit, or RSU, represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001193125-26-206658 · ownership.xml · derivative · entry 3

Parker Craig C · CIK 0001526064 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 12,500

Underlying: Common Stock · 12,500 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit, or RSU, represents a contingent right to receive one share of the Issuer's common stock.

F3 · derivative.exercise_date: These RSUs vest in two equal installments on May 1, 2026 and May 1, 2027.

F3 · derivative.expiration_date: These RSUs vest in two equal installments on May 1, 2026 and May 1, 2027.

SEC source: 0001193125-26-206658 · ownership.xml · nonDerivative · entry 1

Parker Craig C · CIK 0001526064 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 21,077

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit, or RSU, represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001193125-26-206695 · ownership.xml · derivative · entry 5

Li Yang · CIK 0001990537 · Exec. Vice President, Research

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 4,375

Underlying: Common Stock · 4,375 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit, or RSU, represents a contingent right to receive one share of the Issuer's common stock.

F3 · derivative.exercise_date: These RSUs vest in two equal installments on May 1, 2026 and May 1, 2027.

F3 · derivative.expiration_date: These RSUs vest in two equal installments on May 1, 2026 and May 1, 2027.

SEC source: 0001193125-26-206695 · ownership.xml · nonDerivative · entry 1

Li Yang · CIK 0001990537 · Exec. Vice President, Research

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,800

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit, or RSU, represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001193125-26-138292 · ownership.xml · nonDerivative · entry 1

Li Yang · CIK 0001990537 · Exec. Vice President, Research

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,425

F1 · kind: Represents a charitable donation by the Reporting Person.

SEC source: 0001193125-26-124608 · ownership.xml · nonDerivative · entry 4

TCG Crossover GP II, LLC · CIK 0001969280 · 10% owner

TCG Crossover Fund II, L.P. · CIK 0001969281 · 10% owner

TCG Crossover GP III, LLC · CIK 0002062816 · 10% owner

TCG Crossover Fund III, L.P. · CIK 0002062644 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnote

Disclosed balance after: 736,547

F2 · ownership.nature: These securities are held of record by TCG Crossover Fund III, L.P. (TCG Crossover III). TCG Crossover GP III, LLC (TCG Crossover GP III) is the general partner of TCG Crossover III and may be deemed to have voting, investment, and dispositive power with respect to these securities. Chen Yu is the sole managing member of TCG Crossover GP III and may be deemed to share voting, investment and dispositive power with respect to these securities.

SEC source: 0001193125-26-124608 · ownership.xml · nonDerivative · entry 3

TCG Crossover GP II, LLC · CIK 0001969280 · 10% owner

TCG Crossover Fund II, L.P. · CIK 0001969281 · 10% owner

TCG Crossover GP III, LLC · CIK 0002062816 · 10% owner

TCG Crossover Fund III, L.P. · CIK 0002062644 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnote

Disclosed balance after: 736,554

F1 · ownership.nature: These securities are held of record by TCG Crossover Fund II, L.P. (TCG Crossover II). TCG Crossover GP II, LLC (TCG Crossover GP II) is the general partner of TCG Crossover II and may be deemed to have voting, investment, and dispositive power with respect to these securities. Chen Yu is the sole managing member of TCG Crossover GP II and may be deemed to share voting, investment and dispositive power with respect to these securities.

SEC source: 0001193125-26-124608 · ownership.xml · nonDerivative · entry 2

TCG Crossover GP II, LLC · CIK 0001969280 · 10% owner

TCG Crossover Fund II, L.P. · CIK 0001969281 · 10% owner

TCG Crossover GP III, LLC · CIK 0002062816 · 10% owner

TCG Crossover Fund III, L.P. · CIK 0002062644 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnote

Disclosed balance after: 683,218

F2 · ownership.nature: These securities are held of record by TCG Crossover Fund III, L.P. (TCG Crossover III). TCG Crossover GP III, LLC (TCG Crossover GP III) is the general partner of TCG Crossover III and may be deemed to have voting, investment, and dispositive power with respect to these securities. Chen Yu is the sole managing member of TCG Crossover GP III and may be deemed to share voting, investment and dispositive power with respect to these securities.

SEC source: 0001193125-26-124608 · ownership.xml · nonDerivative · entry 1

TCG Crossover GP II, LLC · CIK 0001969280 · 10% owner

TCG Crossover Fund II, L.P. · CIK 0001969281 · 10% owner

TCG Crossover GP III, LLC · CIK 0002062816 · 10% owner

TCG Crossover Fund III, L.P. · CIK 0002062644 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnote

Disclosed balance after: 683,225

F1 · ownership.nature: These securities are held of record by TCG Crossover Fund II, L.P. (TCG Crossover II). TCG Crossover GP II, LLC (TCG Crossover GP II) is the general partner of TCG Crossover II and may be deemed to have voting, investment, and dispositive power with respect to these securities. Chen Yu is the sole managing member of TCG Crossover GP II and may be deemed to share voting, investment and dispositive power with respect to these securities.

SEC source: 0001193125-26-108827 · ownership.xml · nonDerivative · entry 6

TCG Crossover GP II, LLC · CIK 0001969280 · 10% owner

TCG Crossover Fund II, L.P. · CIK 0001969281 · 10% owner

TCG Crossover GP III, LLC · CIK 0002062816 · 10% owner

TCG Crossover Fund III, L.P. · CIK 0002062644 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnote

Disclosed balance after: 675,610

F2 · ownership.nature: These securities are held of record by TCG Crossover Fund III, L.P. (TCG Crossover III). TCG Crossover GP III, LLC (TCG Crossover GP III) is the general partner of TCG Crossover III and may be deemed to have voting, investment, and dispositive power with respect to these securities. Chen Yu is the sole managing member of TCG Crossover GP III and may be deemed to share voting, investment and dispositive power with respect to these securities.

SEC source: 0001193125-26-108827 · ownership.xml · nonDerivative · entry 5

TCG Crossover GP II, LLC · CIK 0001969280 · 10% owner

TCG Crossover Fund II, L.P. · CIK 0001969281 · 10% owner

TCG Crossover GP III, LLC · CIK 0002062816 · 10% owner

TCG Crossover Fund III, L.P. · CIK 0002062644 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnote

Disclosed balance after: 675,613

F1 · ownership.nature: These securities are held of record by TCG Crossover Fund II, L.P. (TCG Crossover II). TCG Crossover GP II, LLC (TCG Crossover GP II) is the general partner of TCG Crossover II and may be deemed to have voting, investment, and dispositive power with respect to these securities. Chen Yu is the sole managing member of TCG Crossover GP II and may be deemed to share voting, investment and dispositive power with respect to these securities.

SEC source: 0001193125-26-108827 · ownership.xml · nonDerivative · entry 4

TCG Crossover GP II, LLC · CIK 0001969280 · 10% owner

TCG Crossover Fund II, L.P. · CIK 0001969281 · 10% owner

TCG Crossover GP III, LLC · CIK 0002062816 · 10% owner

TCG Crossover Fund III, L.P. · CIK 0002062644 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnote

Disclosed balance after: 675,015

F2 · ownership.nature: These securities are held of record by TCG Crossover Fund III, L.P. (TCG Crossover III). TCG Crossover GP III, LLC (TCG Crossover GP III) is the general partner of TCG Crossover III and may be deemed to have voting, investment, and dispositive power with respect to these securities. Chen Yu is the sole managing member of TCG Crossover GP III and may be deemed to share voting, investment and dispositive power with respect to these securities.

SEC source: 0001193125-26-108827 · ownership.xml · nonDerivative · entry 3

TCG Crossover GP II, LLC · CIK 0001969280 · 10% owner

TCG Crossover Fund II, L.P. · CIK 0001969281 · 10% owner

TCG Crossover GP III, LLC · CIK 0002062816 · 10% owner

TCG Crossover Fund III, L.P. · CIK 0002062644 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnote

Disclosed balance after: 675,018

F1 · ownership.nature: These securities are held of record by TCG Crossover Fund II, L.P. (TCG Crossover II). TCG Crossover GP II, LLC (TCG Crossover GP II) is the general partner of TCG Crossover II and may be deemed to have voting, investment, and dispositive power with respect to these securities. Chen Yu is the sole managing member of TCG Crossover GP II and may be deemed to share voting, investment and dispositive power with respect to these securities.

SEC source: 0001193125-26-108827 · ownership.xml · nonDerivative · entry 2

TCG Crossover GP II, LLC · CIK 0001969280 · 10% owner

TCG Crossover Fund II, L.P. · CIK 0001969281 · 10% owner

TCG Crossover GP III, LLC · CIK 0002062816 · 10% owner

TCG Crossover Fund III, L.P. · CIK 0002062644 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnote

Disclosed balance after: 657,299

F2 · ownership.nature: These securities are held of record by TCG Crossover Fund III, L.P. (TCG Crossover III). TCG Crossover GP III, LLC (TCG Crossover GP III) is the general partner of TCG Crossover III and may be deemed to have voting, investment, and dispositive power with respect to these securities. Chen Yu is the sole managing member of TCG Crossover GP III and may be deemed to share voting, investment and dispositive power with respect to these securities.

SEC source: 0001193125-26-108827 · ownership.xml · nonDerivative · entry 1

TCG Crossover GP II, LLC · CIK 0001969280 · 10% owner

TCG Crossover Fund II, L.P. · CIK 0001969281 · 10% owner

TCG Crossover GP III, LLC · CIK 0002062816 · 10% owner

TCG Crossover Fund III, L.P. · CIK 0002062644 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnote

Disclosed balance after: 657,301

F1 · ownership.nature: These securities are held of record by TCG Crossover Fund II, L.P. (TCG Crossover II). TCG Crossover GP II, LLC (TCG Crossover GP II) is the general partner of TCG Crossover II and may be deemed to have voting, investment, and dispositive power with respect to these securities. Chen Yu is the sole managing member of TCG Crossover GP II and may be deemed to share voting, investment and dispositive power with respect to these securities.

SEC source: 0001193125-26-057657 · ownership.xml · derivative · entry 2

Williams Charles O · CIK 0001325818 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 102,900

Underlying: Common Stock · 102,900 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted stock unit, or RSU, represents a contingent right to receive one share of the Issuer's common stock.

F3 · derivative.exercise_date: The shares subject to the RSUs vest in four equal annual installments starting on February 1, 2026, subject to the reporting person's continued service through the applicable vesting date.

F3 · derivative.expiration_date: The shares subject to the RSUs vest in four equal annual installments starting on February 1, 2026, subject to the reporting person's continued service through the applicable vesting date.

SEC source: 0001193125-26-057657 · ownership.xml · derivative · entry 1

Williams Charles O · CIK 0001325818 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 102,900

Underlying: Common Stock · 102,900 shares

Expires 2036-02-16

F1 · derivative.exercise_date: The shares subject to the option award vest over a four-year period in 48 equal monthly installments measured from February 1, 2026, subject to the reporting person's continued service through the applicable vesting date.

SEC source: 0001193125-26-057652 · ownership.xml · derivative · entry 2

Parker Craig C · CIK 0001526064 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 242,200

Underlying: Common Stock · 242,200 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted stock unit, or RSU, represents a contingent right to receive one share of the Issuer's common stock.

F3 · derivative.exercise_date: The shares subject to the RSUs vest in four equal annual installments starting on February 1, 2026, subject to the reporting person's continued service through the applicable vesting date.

F3 · derivative.expiration_date: The shares subject to the RSUs vest in four equal annual installments starting on February 1, 2026, subject to the reporting person's continued service through the applicable vesting date.

SEC source: 0001193125-26-057652 · ownership.xml · derivative · entry 1

Parker Craig C · CIK 0001526064 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 242,200

Underlying: Common Stock · 242,200 shares

Expires 2036-02-16

F1 · derivative.exercise_date: The shares subject to the option award vest over a four-year period in 48 equal monthly installments measured from February 1, 2026, subject to the reporting person's continued service through the applicable vesting date.

SEC source: 0001193125-26-057665 · ownership.xml · derivative · entry 2

Li Yang · CIK 0001990537 · Exec. Vice President, Research

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 100,950

Underlying: Common Stock · 100,950 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted stock unit, or RSU, represents a contingent right to receive one share of the Issuer's common stock.

F3 · derivative.exercise_date: The shares subject to the RSUs vest in four equal annual installments starting on February 1, 2026, subject to the reporting person's continued service through the applicable vesting date.

F3 · derivative.expiration_date: The shares subject to the RSUs vest in four equal annual installments starting on February 1, 2026, subject to the reporting person's continued service through the applicable vesting date.

SEC source: 0001193125-26-057665 · ownership.xml · derivative · entry 1

Li Yang · CIK 0001990537 · Exec. Vice President, Research

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 100,950

Underlying: Common Stock · 100,950 shares

Expires 2036-02-16

F1 · derivative.exercise_date: The shares subject to the option award vest over a four-year period in 48 equal monthly installments measured from February 1, 2026, subject to the reporting person's continued service through the applicable vesting date.

SEC source: 0001193125-26-051452 · ownership.xml · nonDerivative · entry 4

TCG Crossover GP II, LLC · CIK 0001969280 · 10% owner

TCG Crossover Fund II, L.P. · CIK 0001969281 · 10% owner

TCG Crossover GP III, LLC · CIK 0002062816 · 10% owner

TCG Crossover Fund III, L.P. · CIK 0002062644 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnote

Disclosed balance after: 651,112

F2 · ownership.nature: These securities are held of record by TCG Crossover Fund III, L.P. (TCG Crossover III). TCG Crossover GP III, LLC (TCG Crossover GP III) is the general partner of TCG Crossover III and may be deemed to have voting, investment, and dispositive power with respect to these securities. Chen Yu is the sole managing member of TCG Crossover GP III and may be deemed to share voting, investment and dispositive power with respect to these securities.

SEC source: 0001193125-26-051452 · ownership.xml · nonDerivative · entry 3

TCG Crossover GP II, LLC · CIK 0001969280 · 10% owner

TCG Crossover Fund II, L.P. · CIK 0001969281 · 10% owner

TCG Crossover GP III, LLC · CIK 0002062816 · 10% owner

TCG Crossover Fund III, L.P. · CIK 0002062644 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnote

Disclosed balance after: 651,114

F1 · ownership.nature: These securities are held of record by TCG Crossover Fund II, L.P. (TCG Crossover II). TCG Crossover GP II, LLC (TCG Crossover GP II) is the general partner of TCG Crossover II and may be deemed to have voting, investment, and dispositive power with respect to these securities. Chen Yu is the sole managing member of TCG Crossover GP II and may be deemed to share voting, investment and dispositive power with respect to these securities.

SEC source: 0001193125-26-051452 · ownership.xml · nonDerivative · entry 2

TCG Crossover GP II, LLC · CIK 0001969280 · 10% owner

TCG Crossover Fund II, L.P. · CIK 0001969281 · 10% owner

TCG Crossover GP III, LLC · CIK 0002062816 · 10% owner

TCG Crossover Fund III, L.P. · CIK 0002062644 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnote

Disclosed balance after: 650,563

F2 · ownership.nature: These securities are held of record by TCG Crossover Fund III, L.P. (TCG Crossover III). TCG Crossover GP III, LLC (TCG Crossover GP III) is the general partner of TCG Crossover III and may be deemed to have voting, investment, and dispositive power with respect to these securities. Chen Yu is the sole managing member of TCG Crossover GP III and may be deemed to share voting, investment and dispositive power with respect to these securities.

SEC source: 0001193125-26-051452 · ownership.xml · nonDerivative · entry 1

TCG Crossover GP II, LLC · CIK 0001969280 · 10% owner

TCG Crossover Fund II, L.P. · CIK 0001969281 · 10% owner

TCG Crossover GP III, LLC · CIK 0002062816 · 10% owner

TCG Crossover Fund III, L.P. · CIK 0002062644 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnote

Disclosed balance after: 650,567

F1 · ownership.nature: These securities are held of record by TCG Crossover Fund II, L.P. (TCG Crossover II). TCG Crossover GP II, LLC (TCG Crossover GP II) is the general partner of TCG Crossover II and may be deemed to have voting, investment, and dispositive power with respect to these securities. Chen Yu is the sole managing member of TCG Crossover GP II and may be deemed to share voting, investment and dispositive power with respect to these securities.

SEC source: 0001193125-26-036301 · ownership.xml · nonDerivative · entry 6

TCG Crossover GP II, LLC · CIK 0001969280 · 10% owner

TCG Crossover Fund II, L.P. · CIK 0001969281 · 10% owner

TCG Crossover GP III, LLC · CIK 0002062816 · 10% owner

TCG Crossover Fund III, L.P. · CIK 0002062644 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnote

Disclosed balance after: 641,682

F2 · ownership.nature: These securities are held of record by TCG Crossover Fund III, L.P. (TCG Crossover III). TCG Crossover GP III, LLC (TCG Crossover GP III) is the general partner of TCG Crossover III and may be deemed to have voting, investment, and dispositive power with respect to these securities. Chen Yu is the sole managing member of TCG Crossover GP III and may be deemed to share voting, investment and dispositive power with respect to these securities.

SEC source: 0001193125-26-036301 · ownership.xml · nonDerivative · entry 5

TCG Crossover GP II, LLC · CIK 0001969280 · 10% owner

TCG Crossover Fund II, L.P. · CIK 0001969281 · 10% owner

TCG Crossover GP III, LLC · CIK 0002062816 · 10% owner

TCG Crossover Fund III, L.P. · CIK 0002062644 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnote

Disclosed balance after: 641,685

F1 · ownership.nature: These securities are held of record by TCG Crossover Fund II, L.P. (TCG Crossover II). TCG Crossover GP II, LLC (TCG Crossover GP II) is the general partner of TCG Crossover II and may be deemed to have voting, investment, and dispositive power with respect to these securities. Chen Yu is the sole managing member of TCG Crossover GP II and may be deemed to share voting, investment and dispositive power with respect to these securities.

SEC source: 0001193125-26-036301 · ownership.xml · nonDerivative · entry 4

TCG Crossover GP II, LLC · CIK 0001969280 · 10% owner

TCG Crossover Fund II, L.P. · CIK 0001969281 · 10% owner

TCG Crossover GP III, LLC · CIK 0002062816 · 10% owner

TCG Crossover Fund III, L.P. · CIK 0002062644 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnote

Disclosed balance after: 639,505

F2 · ownership.nature: These securities are held of record by TCG Crossover Fund III, L.P. (TCG Crossover III). TCG Crossover GP III, LLC (TCG Crossover GP III) is the general partner of TCG Crossover III and may be deemed to have voting, investment, and dispositive power with respect to these securities. Chen Yu is the sole managing member of TCG Crossover GP III and may be deemed to share voting, investment and dispositive power with respect to these securities.

SEC source: 0001193125-26-036301 · ownership.xml · nonDerivative · entry 3

TCG Crossover GP II, LLC · CIK 0001969280 · 10% owner

TCG Crossover Fund II, L.P. · CIK 0001969281 · 10% owner

TCG Crossover GP III, LLC · CIK 0002062816 · 10% owner

TCG Crossover Fund III, L.P. · CIK 0002062644 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnote

Disclosed balance after: 639,507

F1 · ownership.nature: These securities are held of record by TCG Crossover Fund II, L.P. (TCG Crossover II). TCG Crossover GP II, LLC (TCG Crossover GP II) is the general partner of TCG Crossover II and may be deemed to have voting, investment, and dispositive power with respect to these securities. Chen Yu is the sole managing member of TCG Crossover GP II and may be deemed to share voting, investment and dispositive power with respect to these securities.

SEC source: 0001193125-26-036301 · ownership.xml · nonDerivative · entry 2

TCG Crossover GP II, LLC · CIK 0001969280 · 10% owner

TCG Crossover Fund II, L.P. · CIK 0001969281 · 10% owner

TCG Crossover GP III, LLC · CIK 0002062816 · 10% owner

TCG Crossover Fund III, L.P. · CIK 0002062644 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnote

Disclosed balance after: 639,140

F2 · ownership.nature: These securities are held of record by TCG Crossover Fund III, L.P. (TCG Crossover III). TCG Crossover GP III, LLC (TCG Crossover GP III) is the general partner of TCG Crossover III and may be deemed to have voting, investment, and dispositive power with respect to these securities. Chen Yu is the sole managing member of TCG Crossover GP III and may be deemed to share voting, investment and dispositive power with respect to these securities.

SEC source: 0001193125-26-036301 · ownership.xml · nonDerivative · entry 1

TCG Crossover GP II, LLC · CIK 0001969280 · 10% owner

TCG Crossover Fund II, L.P. · CIK 0001969281 · 10% owner

TCG Crossover GP III, LLC · CIK 0002062816 · 10% owner

TCG Crossover Fund III, L.P. · CIK 0002062644 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnote

Disclosed balance after: 639,141

F1 · ownership.nature: These securities are held of record by TCG Crossover Fund II, L.P. (TCG Crossover II). TCG Crossover GP II, LLC (TCG Crossover GP II) is the general partner of TCG Crossover II and may be deemed to have voting, investment, and dispositive power with respect to these securities. Chen Yu is the sole managing member of TCG Crossover GP II and may be deemed to share voting, investment and dispositive power with respect to these securities.

SEC source: 0001193125-26-022713 · ownership.xml · derivative · entry 1

Williams Charles O · CIK 0001325818 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 500

Underlying: Common Stock · 500 shares

Expires 2036-01-22

F1 · derivative.exercise_date: The shares subject to the option award vest over a four-year period in 48 equal monthly installments measured from grant date, subject to the reporting person's continued service through the applicable vesting date.