RCUS

SEC source: 0001771961-26-000006 · wk-form4_1787608336.xml · derivative · entry 3

Azoy Alexander · CIK 0001771961 · Chief Accounting Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 3,073

Underlying: Common Stock · 2,827 shares

Expires 2034-01-22

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: The option exercises and sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

F3 · derivative.exercise_date: The option becomes exercisable in 48 equal monthly installments after January 1, 2024, subject to the Reporting Person's continued service to the Company.

SEC source: 0001771961-26-000006 · wk-form4_1787608336.xml · nonDerivative · entry 2

Azoy Alexander · CIK 0001771961 · Chief Accounting Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 39,581

F1 · shares: The option exercises and sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

F2 · balance_after: Includes the unvested portion of the Reporting Person's RSU grants.

SEC source: 0001771961-26-000006 · wk-form4_1787608336.xml · nonDerivative · entry 1

Azoy Alexander · CIK 0001771961 · Chief Accounting Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 42,408

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: The option exercises and sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

F2 · balance_after: Includes the unvested portion of the Reporting Person's RSU grants.

SEC source: 0001422996-26-000006 · wk-form4_1783978603.xml · nonDerivative · entry 3

Jaen Juan C. · CIK 0001422996 · President

10b5-1 filing: Plan reported

Ownership: Indirect · By Trust

Disclosed balance after: 822,240

F1 · shares: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

F4 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $29.30 to $29.46, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.

SEC source: 0001422996-26-000006 · wk-form4_1783978603.xml · nonDerivative · entry 2

Jaen Juan C. · CIK 0001422996 · President

10b5-1 filing: Plan reported

Ownership: Indirect · By Trust

Disclosed balance after: 822,508

F1 · shares: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

F3 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $28.17 to $29.01, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.

SEC source: 0001422996-26-000006 · wk-form4_1783978603.xml · nonDerivative · entry 1

Jaen Juan C. · CIK 0001422996 · President

10b5-1 filing: Plan reported

Ownership: Indirect · By Trust

Disclosed balance after: 842,307

F1 · shares: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

F2 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $29.86 to $30.57, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.

SEC source: 0001610717-26-000294 · form4.xml · nonDerivative · entry 4

Jaen Juan C. · CIK 0001422996 · President

10b5-1 filing: Plan reported

Ownership: Indirect · By Trust

Disclosed balance after: 890,809

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on February 27, 2026.

F5 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $29.50 to $29.8050, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.

SEC source: 0001610717-26-000294 · form4.xml · nonDerivative · entry 3

Jaen Juan C. · CIK 0001422996 · President

10b5-1 filing: Plan reported

Ownership: Indirect · By Trust

Disclosed balance after: 897,240

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on February 27, 2026.

F4 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $28.0050 to $28.1550, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.

SEC source: 0001610717-26-000294 · form4.xml · nonDerivative · entry 2

Jaen Juan C. · CIK 0001422996 · President

10b5-1 filing: Plan reported

Ownership: Indirect · By Trust

Disclosed balance after: 898,937

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on February 27, 2026.

F3 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $27.01 to $28.00, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.

SEC source: 0001610717-26-000294 · form4.xml · nonDerivative · entry 1

Jaen Juan C. · CIK 0001422996 · President

10b5-1 filing: Plan reported

Ownership: Indirect · By Trust

Disclosed balance after: 913,004

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on February 27, 2026.

F2 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $27.00 to $27.14, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.

SEC source: 0001836662-26-000005 · wk-form4_1781296090.xml · derivative · entry 2

Tang Carolyn C. · CIK 0001836662 · General Counsel

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 34,090 shares

Expires 2027-08-30

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: The option is fully vested and has been completely exercised.

SEC source: 0001836662-26-000005 · wk-form4_1781296090.xml · nonDerivative · entry 1

Tang Carolyn C. · CIK 0001836662 · General Counsel

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 184,607

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · balance_after: Includes 1,783 shares purchased on May 31, 2026 through the Company's Employee Stock Purchase Plan.

F2 · balance_after: Includes the unvested portion of the Reporting Person's RSU grants.

SEC source: 0001770252-26-000003 · wk-form4_1781296109.xml · derivative · entry 2

Lambert Nicole · CIK 0001770252 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,900

Underlying: Stock Option (Rights to Buy) · 16,900 shares

Expires 2036-06-10

F2 · derivative.exercise_date: The option will vest in full on the earlier of June 11, 2027 or the next annual meeting of stockholders of the issuer. The option will become fully vested and exercisable in the event the Company is subject to a change in control.

SEC source: 0001770252-26-000003 · wk-form4_1781296109.xml · nonDerivative · entry 1

Lambert Nicole · CIK 0001770252 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 43,000

F1 · shares: Represents the grant of restricted stock units that vest in full on the earlier of June 11, 2027 or the next annual meeting of stockholders of the issuer. The RSUs will become fully vested in the event the Company is subject to a change in control.

SEC source: 0001311210-26-000003 · wk-form4_1781296101.xml · derivative · entry 2

Machado Patrick · CIK 0001311210 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,900

Underlying: Stock Option (Rights to Buy) · 16,900 shares

Expires 2036-06-10

F2 · derivative.exercise_date: The option will vest in full on the earlier of June 11, 2027 or the next annual meeting of stockholders of the issuer. The option will become fully vested and exercisable in the event the Company is subject to a change in control.

SEC source: 0001311210-26-000003 · wk-form4_1781296101.xml · nonDerivative · entry 1

Machado Patrick · CIK 0001311210 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 44,300

F1 · shares: Represents the grant of restricted stock units that vest in full on the earlier of June 11, 2027 or the next annual meeting of stockholders of the issuer. The RSUs will become fully vested in the event the Company is subject to a change in control.

SEC source: 0001277503-26-000003 · wk-form4_1781296095.xml · derivative · entry 5

KANEKO YASUNORI · CIK 0001277503 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,900

Underlying: Stock Option (Rights to Buy) · 16,900 shares

Expires 2036-06-10

F3 · derivative.exercise_date: The option will vest in full on the earlier of June 11, 2027 or the next annual meeting of stockholders of the issuer. The option will become fully vested and exercisable in the event the Company is subject to a change in control.

SEC source: 0001277503-26-000003 · wk-form4_1781296095.xml · nonDerivative · entry 1

KANEKO YASUNORI · CIK 0001277503 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 25,700

F1 · shares: Represents the grant of restricted stock units that vest in full on the earlier of June 11, 2027 or the next annual meeting of stockholders of the issuer. The RSUs will become fully vested in the event the Company is subject to a change in control.

SEC source: 0001734422-26-000005 · wk-form4_1781296084.xml · derivative · entry 2

Lacey David L. · CIK 0001734422 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,900

Underlying: Stock Option (Rights to Buy) · 16,900 shares

Expires 2036-06-10

F2 · derivative.exercise_date: The option will vest in full on the earlier of June 11, 2027 or the next annual meeting of stockholders of the issuer. The option will become fully vested and exercisable in the event the Company is subject to a change in control.

SEC source: 0001734422-26-000005 · wk-form4_1781296084.xml · nonDerivative · entry 1

Lacey David L. · CIK 0001734422 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 76,652

F1 · shares: Represents the grant of restricted stock units that vest in full on the earlier of June 11, 2027 or the next annual meeting of stockholders of the issuer. The RSUs will become fully vested in the event the Company is subject to a change in control.

SEC source: 0001206977-26-000009 · wk-form4_1781296077.xml · derivative · entry 3

FALBERG KATHRYN E · CIK 0001206977 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,900

Underlying: Stock Option (Rights to Buy) · 16,900 shares

Expires 2036-06-10

F3 · derivative.exercise_date: The option will vest in full on the earlier of June 11, 2027 or the next annual meeting of stockholders of the issuer. The option will become fully vested and exercisable in the event the Company is subject to a change in control.

SEC source: 0001206977-26-000009 · wk-form4_1781296077.xml · nonDerivative · entry 1

FALBERG KATHRYN E · CIK 0001206977 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 44,300

F1 · shares: Represents the grant of restricted stock units that vest in full on the earlier of June 11, 2027 or the next annual meeting of stockholders of the issuer. The RSUs will become fully vested in the event the Company is subject to a change in control.

SEC source: 0001792164-26-000006 · wk-form4_1781296071.xml · derivative · entry 3

Ribas Antoni · CIK 0001792164 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,900

Underlying: Stock Option (Rights to Buy) · 16,900 shares

Expires 2036-06-10

F2 · derivative.exercise_date: The option will vest in full on the earlier of June 11, 2027 or the next annual meeting of stockholders of the issuer. The option will become fully vested and exercisable in the event the Company is subject to a change in control.

SEC source: 0001792164-26-000006 · wk-form4_1781296071.xml · nonDerivative · entry 1

Ribas Antoni · CIK 0001792164 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 44,300

F1 · shares: Represents the grant of restricted stock units that vest in full on the earlier of June 11, 2027 or the next annual meeting of stockholders of the issuer. The RSUs will become fully vested in the event the Company is subject to a change in control.

SEC source: 0001201617-26-000003 · wk-form4_1781296065.xml · derivative · entry 2

PERLMAN ANDREW J · CIK 0001201617 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,900

Underlying: Stock Option (Rights to Buy) · 16,900 shares

Expires 2036-06-10

F2 · derivative.exercise_date: The option will vest in full on the earlier of June 11, 2027 or the next annual meeting of stockholders of the issuer. The option will become fully vested and exercisable in the event the Company is subject to a change in control.

SEC source: 0001201617-26-000003 · wk-form4_1781296065.xml · nonDerivative · entry 1

PERLMAN ANDREW J · CIK 0001201617 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 48,325

F1 · shares: Represents the grant of restricted stock units that vest in full on the earlier of June 11, 2027 or the next annual meeting of stockholders of the issuer. The RSUs will become fully vested in the event the Company is subject to a change in control.

SEC source: 0001771961-26-000004 · wk-form4_1780356235.xml · nonDerivative · entry 1

Azoy Alexander · CIK 0001771961 · Chief Accounting Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 39,581

F1 · shares: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

F2 · shares: Consists of 2,562 shares purchased on 5/29/2026 through the Company's Employee Stock Purchase Plan.

F3 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $25.67 to $25.90, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.

F4 · balance_after: Includes the unvested portion of the Reporting Person's RSU grants.

SEC source: 0001653881-26-000005 · wk-form4_1778616546.xml · nonDerivative · entry 1

Goeltz II Robert C. · CIK 0001653881 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 84,161

F1 · shares: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

F2 · balance_after: Includes the unvested portion of the reporting person's RSU grants.

SEC source: 0002056093-26-000002 · wk-form4_1769476911.xml · derivative · entry 2

Markus Richard · CIK 0002056093 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 96,000

Underlying: Common Stock · 96,000 shares

Expires 2036-01-22

F3 · derivative.exercise_date: The option becomes exercisable in 48 equal monthly installments after January 1, 2026, subject to the Reporting Person's continued service to the Company.

SEC source: 0002056093-26-000002 · wk-form4_1769476911.xml · nonDerivative · entry 1

Markus Richard · CIK 0002056093 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 89,647

F1 · shares: Represents the grant of restricted stock units that vest in four equal annual installments beginning December 15, 2026, subject to the Reporting Person's continued service to the Company.

F2 · balance_after: Includes the unvested portion of the Reporting Person's RSU grants.

SEC source: 0001836662-26-000002 · wk-form4_1769476892.xml · derivative · entry 2

Tang Carolyn C. · CIK 0001836662 · General Counsel

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 96,000

Underlying: Common Stock · 96,000 shares

Expires 2036-01-22

F3 · derivative.exercise_date: The option becomes exercisable in 48 equal monthly installments after January 1, 2026, subject to the Reporting Person's continued service to the Company.

SEC source: 0001836662-26-000002 · wk-form4_1769476892.xml · nonDerivative · entry 1

Tang Carolyn C. · CIK 0001836662 · General Counsel

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 148,734

F1 · shares: Represents the grant of restricted stock units that vest in four equal annual installments beginning December 15, 2026, subject to the Reporting Person's continued service to the Company.

F2 · balance_after: Includes the unvested portion of the Reporting Person's RSU grants.

SEC source: 0001653881-26-000002 · wk-form4_1769476886.xml · derivative · entry 2

Goeltz II Robert C. · CIK 0001653881 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 96,000

Underlying: Common Stock · 96,000 shares

Expires 2036-01-22

F3 · derivative.exercise_date: The option becomes exercisable in 48 equal monthly installments after January 1, 2026, subject to the Reporting Person's continued service to the Company.

SEC source: 0001653881-26-000002 · wk-form4_1769476886.xml · nonDerivative · entry 1

Goeltz II Robert C. · CIK 0001653881 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 91,924

F1 · shares: Represents the grant of restricted stock units that vest in four equal annual installments beginning December 15, 2026, subject to the Reporting Person's continued service to the Company.

F2 · balance_after: Includes the unvested portion of the Reporting Person's RSU grants.

SEC source: 0001182473-26-000005 · wk-form4_1769476905.xml · derivative · entry 2

ROSEN TERRY J · CIK 0001182473 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 315,000

Underlying: Common Stock · 315,000 shares

Expires 2036-01-22

F3 · derivative.exercise_date: The option becomes exercisable in 48 equal monthly installments after January 1, 2026, subject to the Reporting Person's continued service to the Company.

SEC source: 0001182473-26-000005 · wk-form4_1769476905.xml · nonDerivative · entry 1

ROSEN TERRY J · CIK 0001182473 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,236,409

F1 · shares: Represents the grant of restricted stock units that vest in four equal annual installments beginning December 15, 2026, subject to the Reporting Person's continued service to the Company.

F2 · balance_after: Includes the unvested portion of the Reporting Person's RSU grants.

SEC source: 0001422996-26-000004 · wk-form4_1769476899.xml · derivative · entry 3

Jaen Juan C. · CIK 0001422996 · President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 126,000

Underlying: Common Stock · 126,000 shares

Expires 2036-01-22

F3 · derivative.exercise_date: The option becomes exercisable in 48 equal monthly installments after January 1, 2026, subject to the Reporting Person's continued service to the Company.

SEC source: 0001422996-26-000004 · wk-form4_1769476899.xml · nonDerivative · entry 1

Jaen Juan C. · CIK 0001422996 · President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 377,012

F1 · shares: Represents the grant of restricted stock units that vest in four equal annual installments beginning December 15, 2026, subject to the Reporting Person's continued service to the Company.

F2 · balance_after: Includes the unvested portion of the Reporting Person's RSU grants.

SEC source: 0001671311-26-000002 · wk-form4_1769476873.xml · derivative · entry 2

Jarrett Jennifer · CIK 0001671311 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 126,000

Underlying: Common Stock · 126,000 shares

Expires 2036-01-22

F3 · derivative.exercise_date: The option becomes exercisable in 48 equal monthly installments after January 1, 2026, subject to the Reporting Person's continued service to the Company.

SEC source: 0001671311-26-000002 · wk-form4_1769476873.xml · nonDerivative · entry 1

Jarrett Jennifer · CIK 0001671311 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 224,024

F1 · shares: Represents the grant of restricted stock units that vest in four equal annual installments beginning December 15, 2026, subject to the Reporting Person's continued service to the Company.

F2 · balance_after: Includes the unvested portion of the Reporting Person's RSU grants.

SEC source: 0001771961-26-000002 · wk-form4_1769476880.xml · derivative · entry 2

Azoy Alexander · CIK 0001771961 · Chief Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,050

Underlying: Common Stock · 14,050 shares

Expires 2036-01-22

F3 · derivative.exercise_date: The option becomes exercisable in 48 equal monthly installments after January 1, 2026, subject to the Reporting Person's continued service to the Company.

SEC source: 0001771961-26-000002 · wk-form4_1769476880.xml · nonDerivative · entry 1

Azoy Alexander · CIK 0001771961 · Chief Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 39,581

F1 · shares: Represents the grant of restricted stock units that vest in four equal annual installments beginning December 15, 2026, subject to the Reporting Person's continued service to the Company.

F2 · balance_after: Includes the unvested portion of the Reporting Person's RSU grants.

SEC source: 0001182473-26-000003 · wk-form4_1767993968.xml · nonDerivative · entry 1

ROSEN TERRY J · CIK 0001182473 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,157,409

F1 · kind: Represents a charitable gift by the reporting person.

F2 · balance_after: Includes the unvested portion of the reporting person's RSU grants.

SEC source: 0001422996-26-000002 · wk-form4_1767820531.xml · nonDerivative · entry 3

Jaen Juan C. · CIK 0001422996 · President

10b5-1 filing: Plan reported

Ownership: Indirect · By Trust

Disclosed balance after: 922,240

F1 · shares: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on August 8, 2025.

SEC source: 0001422996-26-000002 · wk-form4_1767820531.xml · nonDerivative · entry 2

Jaen Juan C. · CIK 0001422996 · President

10b5-1 filing: Plan reported

Ownership: Indirect · By Trust

Disclosed balance after: 922,340

F1 · shares: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on August 8, 2025.

F3 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $22.04 to $22.985, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.

SEC source: 0001422996-26-000002 · wk-form4_1767820531.xml · nonDerivative · entry 1

Jaen Juan C. · CIK 0001422996 · President

10b5-1 filing: Plan reported

Ownership: Indirect · By Trust

Disclosed balance after: 924,393

F1 · shares: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on August 8, 2025.

F2 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $20.975 to $21.84, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.

SEC source: 0001610717-26-000002 · form4.xml · nonDerivative · entry 1

Goeltz II Robert C. · CIK 0001653881 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 67,924

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0001610717-26-000001 · form4.xml · nonDerivative · entry 1

ROSEN TERRY J · CIK 0001182473 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,192,409

F1 · kind: 2,400 shares were transferred to various family trusts in which the reporting person has no pecuniary interest, but retains voting and dispositive power over all of the shares transferred to each trust.

SEC source: 0001771961-25-000014 · wk-form4_1766097326.xml · nonDerivative · entry 3

Azoy Alexander · CIK 0001771961 · Chief Accounting Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 18,531

F5 · shares: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on June 6, 2025.

F6 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $21.90 to $22.59, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.

F3 · balance_after: Includes the unvested portion of the reporting person's RSU grants.

SEC source: 0002056093-25-000005 · wk-form4_1766097334.xml · nonDerivative · entry 2

Markus Richard · CIK 0002056093 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 65,647

F1 · shares: Represents shares sold by the issuer on the reporting person's behalf to cover tax withholding obligations in connection with the vesting of certain RSUs (previously reported in Table I) following the date of grant. The sale occurred automatically pursuant to the Issuer's equity administration policy, which was implemented on May 22, 2025, and does not represent a discretionary trade by the reporting person.

F4 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $21.92 to $22.42, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.

F3 · balance_after: Includes the unvested portion of the reporting person's RSU grants.