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Ultragenyx Pharmaceutical Inc.

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4337
SEC CIK
0001515673
Parsed reports
478

Last 12 months

Inside the activity.

0 purchase rows · 27 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202500
Dec 202502
Jan 202601
Feb 202601
Mar 2026011
Apr 202601
May 202603
Jun 202603
Jul 202601
Aug 202602
Sep 202602
Oct 202600

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
September 13, 2021 Filed Oct 18, 2021 22:53 UTC
Huizenga Theodore AlanSVP, Chief Accounting Officer
GiftCommon Stock 819 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-060756 · doc4.xml · nonDerivative · entry 1

Huizenga Theodore Alan · CIK 0001603347 · SVP, Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,212

Read SEC document
September 08, 2021 Filed Sep 9, 2021 22:22 UTC
Parschauer Karah HerdmanEVP and General Counsel
Exercise / conversionStock Option (Right to Buy) · Derivative 7,336 $0.00 Strike: $54.50 $0.00
Disclosure

SEC source: 0001209191-21-055362 · doc4.xml · derivative · entry 3

Parschauer Karah Herdman · CIK 0001677455 · EVP and General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,664

Underlying: Common Stock · 7,336 shares

Expires 2026-06-20

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vested with respect to 1/4th of the shares on June 20, 2017 (the first anniversary of the grant date of the option or the "Option Anniversary Date") and 1/48th of the shares initially subject to the option continued to vest on each month as measured from the Option Anniversary Date such that the option fully vested on the fourth anniversary of the grant date.

Read SEC document
September 08, 2021 Filed Sep 9, 2021 22:22 UTC
Parschauer Karah HerdmanEVP and General Counsel
SaleCommon Stock 7,336 $100.65 $738,368.40
Disclosure

SEC source: 0001209191-21-055362 · doc4.xml · nonDerivative · entry 2

Parschauer Karah Herdman · CIK 0001677455 · EVP and General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,668

F1 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

Read SEC document
September 08, 2021 Filed Sep 9, 2021 22:22 UTC
Parschauer Karah HerdmanEVP and General Counsel
Exercise / conversionCommon Stock 7,336 $54.50 $399,812.00
Disclosure

SEC source: 0001209191-21-055362 · doc4.xml · nonDerivative · entry 1

Parschauer Karah Herdman · CIK 0001677455 · EVP and General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,004

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
September 02, 2021 Filed Sep 2, 2021 22:11 UTC
Bedrosian Camille LEVP and Chief Medical Officer
Exercise / conversionStock Option (Right to Buy) · Derivative 2,500 $0.00 Strike: $55.00 $0.00
Disclosure

SEC source: 0001209191-21-054542 · doc4.xml · derivative · entry 6

Bedrosian Camille L · CIK 0001326969 · EVP and Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 53,000

Underlying: Common Stock · 2,500 shares

Expires 2028-01-30

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: The option vested with respect to 1/4th of the shares on January 30, 2019 (the first anniversary of the grant date of the option or the "Option Anniversary Date") and 1/48th of the shares initially subject to the option continued to vest on each month as measured from the Option Anniversary Date such that the option will fully vest on the fourth anniversary of the grant date.

Read SEC document
September 02, 2021 Filed Sep 2, 2021 22:11 UTC
Bedrosian Camille LEVP and Chief Medical Officer
SaleCommon Stock 2,500 $100.18 $250,450.00
Disclosure

SEC source: 0001209191-21-054542 · doc4.xml · nonDerivative · entry 4

Bedrosian Camille L · CIK 0001326969 · EVP and Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,775

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $100.00 to $100.42 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
September 02, 2021 Filed Sep 2, 2021 22:11 UTC
Bedrosian Camille LEVP and Chief Medical Officer
Exercise / conversionCommon Stock 2,500 $55.00 $137,500.00
Disclosure

SEC source: 0001209191-21-054542 · doc4.xml · nonDerivative · entry 3

Bedrosian Camille L · CIK 0001326969 · EVP and Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,275

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
September 01, 2021 Filed Sep 2, 2021 22:11 UTC
Bedrosian Camille LEVP and Chief Medical Officer
Exercise / conversionStock Option (Right to Buy) · Derivative 2,500 $0.00 Strike: $55.00 $0.00
Disclosure

SEC source: 0001209191-21-054542 · doc4.xml · derivative · entry 5

Bedrosian Camille L · CIK 0001326969 · EVP and Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 55,500

Underlying: Common Stock · 2,500 shares

Expires 2028-01-30

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: The option vested with respect to 1/4th of the shares on January 30, 2019 (the first anniversary of the grant date of the option or the "Option Anniversary Date") and 1/48th of the shares initially subject to the option continued to vest on each month as measured from the Option Anniversary Date such that the option will fully vest on the fourth anniversary of the grant date.

Read SEC document
September 01, 2021 Filed Sep 2, 2021 22:11 UTC
Bedrosian Camille LEVP and Chief Medical Officer
SaleCommon Stock 2,500 $100.03 $250,075.00
Disclosure

SEC source: 0001209191-21-054542 · doc4.xml · nonDerivative · entry 2

Bedrosian Camille L · CIK 0001326969 · EVP and Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,775

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $100.00 to $100.10 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
September 01, 2021 Filed Sep 2, 2021 22:11 UTC
Bedrosian Camille LEVP and Chief Medical Officer
Exercise / conversionCommon Stock 2,500 $55.00 $137,500.00
Disclosure

SEC source: 0001209191-21-054542 · doc4.xml · nonDerivative · entry 1

Bedrosian Camille L · CIK 0001326969 · EVP and Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,275

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported on this Form 4 were effected pursuant to a trading plan adopted by the Reporting Person pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

Read SEC document
July 06, 2021 Filed Jul 8, 2021 15:56 UTC
Harris ErikEVP & Chief Commercial Officer
SaleCommon Stock 375 $91.53 $34,323.75
Disclosure

SEC source: 0001209191-21-045972 · doc4.xml · nonDerivative · entry 1

Harris Erik · CIK 0001780113 · EVP & Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,333

F1 · kind: Represents shares sold to pay required tax withholdings due to the vesting of Restricted Stock Units ("RSUs").

F2 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

Read SEC document
June 29, 2021 Filed Jun 30, 2021 23:58 UTC GrantStock Option (Right to Buy) · Derivative 7,255 $0.00 Strike: $96.29 $0.00
Disclosure

SEC source: 0001209191-21-044165 · doc4.xml · derivative · entry 2

Sanders Corazon (Corsee) D. · CIK 0001796536 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,255

Underlying: Common Stock · 7,255 shares

Expires 2031-06-29

F2 · derivative.exercise_date: The option shall vest with respect to 1/36th of the shares monthly such that the option shall fully vest on the third anniversary of the grant date.

Read SEC document
June 29, 2021 Filed Jun 30, 2021 23:58 UTC GrantCommon Stock 3,895 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-044165 · doc4.xml · nonDerivative · entry 1

Sanders Corazon (Corsee) D. · CIK 0001796536 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,895

F1 · shares: Award of Restricted Stock Units ("RSUs") under the Company's 2014 Incentive Plan. The RSUs shall vest with respect to 1/3rd of the underlying shares on each anniversary of the grant date, such that the RSUs are fully vested on the third anniversary of the grant date.

Read SEC document
June 24, 2021 Filed Jun 28, 2021 22:27 UTC GrantStock Option (Right to Buy) · Derivative 4,125 $0.00 Strike: $93.20 $0.00
Disclosure

SEC source: 0001209191-21-043549 · doc4.xml · derivative · entry 2

WELCH DANIEL G · CIK 0001206199 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,125

Underlying: Common Stock · 4,125 shares

Expires 2031-06-24

F2 · derivative.exercise_date: The option shall vest in full on the earlier of (i) the Company's next Annual Meeting of Stockholders or (ii) June 24, 2022.

Read SEC document
June 24, 2021 Filed Jun 28, 2021 22:27 UTC GrantCommon Stock 2,145 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-043549 · doc4.xml · nonDerivative · entry 1

WELCH DANIEL G · CIK 0001206199 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,445

F1 · shares: Award of Restricted Stock Units ("RSUs") under the Company's 2014 Incentive Plan. The RSUs shall vest in full on the earlier of (i) the Company's next Annual Meeting of Stockholders or (ii) June 24, 2022.

Read SEC document
June 24, 2021 Filed Jun 28, 2021 22:25 UTC GrantStock Option (Right to Buy) · Derivative 4,125 $0.00 Strike: $93.20 $0.00
Disclosure

SEC source: 0001209191-21-043545 · doc4.xml · derivative · entry 2

Dunsire Deborah · CIK 0001332764 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,125

Underlying: Common Stock · 4,125 shares

Expires 2031-06-24

F2 · derivative.exercise_date: The option shall vest in full on the earlier of (i) the Company's next Annual Meeting of Stockholders or (ii) June 24, 2022.

Read SEC document
June 24, 2021 Filed Jun 28, 2021 22:25 UTC GrantCommon stock 2,145 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-043545 · doc4.xml · nonDerivative · entry 1

Dunsire Deborah · CIK 0001332764 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,570

F1 · shares: Award of Restricted Stock Units ("RSUs") under the Company's 2014 Incentive Plan. The RSUs shall vest in full on the earlier of (i) the Company's next Annual Meeting of Stockholders or (ii) June 24, 2022.

Read SEC document
June 24, 2021 Filed Jun 28, 2021 18:23 UTC GrantStock Option (Right to Buy) · Derivative 4,125 $0.00 Strike: $93.20 $0.00
Disclosure

SEC source: 0001209191-21-043538 · doc4.xml · derivative · entry 2

NARACHI MICHAEL · CIK 0001380022 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,125

Underlying: Common Stock · 4,125 shares

Expires 2031-06-24

F2 · derivative.exercise_date: The option shall vest in full on the earlier of (i) the Company's next Annual Meeting of Stockholders or (ii) June 24, 2022.

Read SEC document
June 24, 2021 Filed Jun 28, 2021 18:23 UTC GrantCommon Stock 2,145 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-043538 · doc4.xml · nonDerivative · entry 1

NARACHI MICHAEL · CIK 0001380022 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,445

F1 · shares: Award of Restricted Stock Units ("RSUs") under the Company's 2014 Incentive Plan. The RSUs shall vest in full on the earlier of (i) the Company's next Annual Meeting of Stockholders or (ii) June 24, 2022.

Read SEC document
June 24, 2021 Filed Jun 28, 2021 22:24 UTC
Ekman LarsDirector
GrantStock Option (Right to Buy) · Derivative 4,125 $0.00 Strike: $93.20 $0.00
Disclosure

SEC source: 0001209191-21-043543 · doc4.xml · derivative · entry 2

Ekman Lars · CIK 0001376117 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,125

Underlying: Common Stock · 4,125 shares

Expires 2031-06-24

F2 · derivative.exercise_date: The option shall vest in full on the earlier of (i) the Company's next Annual Meeting of Stockholders or (ii) June 24, 2022.

Read SEC document
June 24, 2021 Filed Jun 28, 2021 22:24 UTC
Ekman LarsDirector
GrantCommon Stock 2,145 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-043543 · doc4.xml · nonDerivative · entry 1

Ekman Lars · CIK 0001376117 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,445

F1 · shares: Award of Restricted Stock Units ("RSUs") under the Company's 2014 Incentive Plan. The RSUs shall vest in full on the earlier of (i) the Company's next Annual Meeting of Stockholders or (ii) June 24, 2022.

Read SEC document
June 24, 2021 Filed Jun 28, 2021 22:24 UTC GrantStock Option (Right to Buy) · Derivative 4,125 $0.00 Strike: $93.20 $0.00
Disclosure

SEC source: 0001209191-21-043540 · doc4.xml · derivative · entry 2

Fust Matthew K · CIK 0001397266 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,125

Underlying: Common Stock · 4,125 shares

Expires 2031-06-24

F2 · derivative.exercise_date: The option shall vest in full on the earlier of (i) the Company's next Annual Meeting of Stockholders or (ii) June 24, 2022.

Read SEC document
June 24, 2021 Filed Jun 28, 2021 22:24 UTC GrantCommon Stock 2,145 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-043540 · doc4.xml · nonDerivative · entry 1

Fust Matthew K · CIK 0001397266 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,695

F1 · shares: Award of Restricted Stock Units ("RSUs") under the Company's 2014 Incentive Plan. The RSUs shall vest in full on the earlier of (i) the Company's next Annual Meeting of Stockholders or (ii) June 24, 2022.

Read SEC document
June 24, 2021 Filed Jun 28, 2021 22:26 UTC GrantStock Option (Right to Buy) · Derivative 4,125 $0.00 Strike: $93.20 $0.00
Disclosure

SEC source: 0001209191-21-043547 · doc4.xml · derivative · entry 4

Aliski William · CIK 0001598426 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,125

Underlying: Common Stock · 4,125 shares

Expires 2031-06-24

F4 · derivative.exercise_date: The option shall vest in full on the earlier of (i) the Company's next Annual Meeting of Stockholders or (ii) June 24, 2022.

Read SEC document
June 24, 2021 Filed Jun 28, 2021 22:26 UTC GrantCommon Stock 2,145 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-043547 · doc4.xml · nonDerivative · entry 1

Aliski William · CIK 0001598426 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 66,849

F1 · shares: Award of Restricted Stock Units ("RSUs") under the Company's 2014 Incentive Plan. The RSUs shall vest in full on the earlier of (i) the Company's next Annual Meeting of Stockholders or (ii) June 24, 2022.

Read SEC document
June 24, 2021 Filed Jun 28, 2021 22:22 UTC GrantStock Option (Right to Buy) · Derivative 4,125 $0.00 Strike: $93.20 $0.00
Disclosure

SEC source: 0001209191-21-043535 · doc4.xml · derivative · entry 2

SULIMAN SHEHNAAZ · CIK 0001713070 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,125

Underlying: Common Stock · 4,125 shares

Expires 2031-06-24

F2 · derivative.exercise_date: The option shall vest in full on the earlier of (i) the Company's next Annual Meeting of Stockholders or (ii) June 24, 2022.

Read SEC document
June 24, 2021 Filed Jun 28, 2021 22:22 UTC GrantCommon Stock 2,145 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-043535 · doc4.xml · nonDerivative · entry 1

SULIMAN SHEHNAAZ · CIK 0001713070 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,695

F1 · shares: Award of Restricted Stock Units ("RSUs") under the Company's 2014 Incentive Plan. The RSUs shall vest in full on the earlier of (i) the Company's next Annual Meeting of Stockholders or (ii) June 24, 2022.

Read SEC document
June 21, 2021 Filed Jun 23, 2021 21:55 UTC
Harris ErikEVP & Chief Commercial Officer
SaleCommon Stock 572 $94.96 $54,317.12
Disclosure

SEC source: 0001209191-21-042812 · doc4.xml · nonDerivative · entry 2

Harris Erik · CIK 0001780113 · EVP & Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,708

F2 · kind: The sales reported on the transaction date of June 21, 2021 were effected pursuant to a trading plan adopted by the Reporting Person pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F3 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

Read SEC document
June 19, 2021 Filed Jun 23, 2021 21:55 UTC
Harris ErikEVP & Chief Commercial Officer
SaleCommon Stock 437 $94.63 $41,353.31
Disclosure

SEC source: 0001209191-21-042812 · doc4.xml · nonDerivative · entry 1

Harris Erik · CIK 0001780113 · EVP & Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,280

F1 · kind: Represents shares sold to pay required tax withholdings due to the vesting of RSUs.

Read SEC document
June 10, 2021 Filed Jun 12, 2021 01:08 UTC
Parschauer Karah HerdmanEVP and General Counsel
SaleCommon Stock 1,329 $100.00 $132,900.00
Disclosure

SEC source: 0001209191-21-040108 · doc4.xml · nonDerivative · entry 1

Parschauer Karah Herdman · CIK 0001677455 · EVP and General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,668

F1 · kind: The sales reported on this Form 4 were effected pursuant to a trading plan adopted by the Reporting Person pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F2 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

Read SEC document
May 07, 2021 Filed May 10, 2021 22:10 UTC
Harris ErikEVP & Chief Commercial Officer
SaleCommon Stock 393 $113.67 $44,672.31
Disclosure

SEC source: 0001209191-21-031378 · doc4.xml · nonDerivative · entry 2

Harris Erik · CIK 0001780113 · EVP & Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,717

F2 · kind: The sales reported on the transaction date of May 7, 2021 on this Form 4 were effected pursuant to a trading plan adopted by the Reporting Person pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F3 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

Read SEC document
May 06, 2021 Filed May 10, 2021 22:11 UTC SaleCommon Stock 363 $113.69 $41,269.47
Disclosure

SEC source: 0001209191-21-031384 · doc4.xml · nonDerivative · entry 1

Kassberg Thomas Richard · CIK 0001303811 · CBO & EVP

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 106,818

F1 · kind: Represents shares sold to pay required tax withholdings due to the vesting of RSUs.

F2 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

Read SEC document
May 06, 2021 Filed May 10, 2021 22:11 UTC
KAKKIS EMIL DDirector · President & CEO
Tax withholdingCommon Stock 852 $115.71 $98,584.92
Disclosure

SEC source: 0001209191-21-031383 · doc4.xml · nonDerivative · entry 1

KAKKIS EMIL D · CIK 0001248093 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 595,200

F1 · kind: Represents shares surrendered to the Issuer by the Reporting Person to pay required tax withholdings due to the vesting of RSUs.

F2 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

Read SEC document
May 06, 2021 Filed May 10, 2021 22:09 UTC
Bedrosian Camille LEVP and Chief Medical Officer
SaleCommon Stock 364 $113.67 $41,375.88
Disclosure

SEC source: 0001209191-21-031376 · doc4.xml · nonDerivative · entry 1

Bedrosian Camille L · CIK 0001326969 · EVP and Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,775

F1 · kind: Represents shares sold to pay required tax withholdings due to the vesting of RSUs.

F2 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

Read SEC document
May 06, 2021 Filed May 10, 2021 22:14 UTC
Huang Dennis KarlEVP & Chief Tech Ops Officer
SaleCommon Stock 363 $113.68 $41,265.84
Disclosure

SEC source: 0001209191-21-031390 · doc4.xml · nonDerivative · entry 1

Huang Dennis Karl · CIK 0001641217 · EVP & Chief Tech Ops Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,506

F1 · kind: Represents shares sold to pay required tax withholdings due to the vesting of RSUs.

F2 · balance_after: Includes 108 shares acquired under the Company's 2014 Employee Stock Purchase Plan on April 30, 2021.

F3 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

Read SEC document
May 06, 2021 Filed May 10, 2021 22:13 UTC
Parschauer Karah HerdmanEVP and General Counsel
SaleCommon Stock 313 $113.67 $35,578.71
Disclosure

SEC source: 0001209191-21-031388 · doc4.xml · nonDerivative · entry 1

Parschauer Karah Herdman · CIK 0001677455 · EVP and General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,997

F1 · kind: Represents shares sold to pay required tax withholdings due to the vesting of RSUs.

F2 · balance_after: Includes 83 shares acquired under the Company's 2014 Employee Stock Purchase Plan on April 30, 2021.

F3 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

Read SEC document
May 06, 2021 Filed May 10, 2021 22:13 UTC SaleCommon Stock 363 $113.69 $41,269.47
Disclosure

SEC source: 0001209191-21-031387 · doc4.xml · nonDerivative · entry 1

Pinion John Richard · CIK 0001648096 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 50,122

F1 · kind: Represents shares sold to pay required tax withholdings due to the vesting of RSUs.

F2 · balance_after: Includes 248 shares acquired under the Company's 2014 Employee Stock Purchase Plan on April 30, 2021.

F3 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

Read SEC document
May 06, 2021 Filed May 10, 2021 22:12 UTC
Huizenga Theodore AlanSVP, Chief Accounting Officer
SaleCommon Stock 142 $113.67 $16,141.14
Disclosure

SEC source: 0001209191-21-031386 · doc4.xml · nonDerivative · entry 1

Huizenga Theodore Alan · CIK 0001603347 · SVP, Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,031

F1 · kind: Represents shares sold to pay required tax withholdings due to the vesting of RSUs.

F2 · balance_after: Includes 129 shares acquired under the Company's 2014 Employee Stock Purchase Plan on April 30, 2021.

F3 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

Read SEC document
May 06, 2021 Filed May 10, 2021 22:10 UTC
Harris ErikEVP & Chief Commercial Officer
SaleCommon Stock 307 $113.68 $34,899.76
Disclosure

SEC source: 0001209191-21-031378 · doc4.xml · nonDerivative · entry 1

Harris Erik · CIK 0001780113 · EVP & Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,110

F1 · kind: Represents shares sold to pay required tax withholdings due to the vesting of RSUs.

Read SEC document
May 03, 2021 Filed May 5, 2021 15:32 UTC
KAKKIS EMIL DDirector · President & CEO
SaleCommon Stock 30,000 $107.80 $3,234,000.00
Disclosure

SEC source: 0001209191-21-030211 · doc4.xml · nonDerivative · entry 1

KAKKIS EMIL D · CIK 0001248093 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Emil Kakkis and Jenny Soriano Living Trust, dated June 18, 200

Disclosed balance after: 2,259,741

F1 · kind: The transactions reported on this Form 4 were effected pursuant to a trading plan adopted by the Reporting Person pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $106.14 to $110.45 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

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April 20, 2021 Filed Apr 22, 2021 00:07 UTC
Harris ErikEVP & Chief Commercial Officer
SaleCommon Stock 396 $104.28 $41,294.88
Disclosure

SEC source: 0001209191-21-027881 · doc4.xml · nonDerivative · entry 1

Harris Erik · CIK 0001780113 · EVP & Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,417

F1 · kind: The transactions reported on this Form 4 were effected pursuant to a trading plan adopted by the Reporting Person pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F2 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

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April 16, 2021 Filed Apr 19, 2021 21:16 UTC
Huizenga Theodore AlanSVP, Chief Accounting Officer
GrantCommon Stock 1,500 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-027328 · doc4.xml · nonDerivative · entry 1

Huizenga Theodore Alan · CIK 0001603347 · SVP, Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,044

F1 · shares: Award of Restricted Stock Units ("RSUs") under the Company's 2014 Incentive Plan. The RSUs shall vest with respect to 1/4th of the underlying shares on each anniversary of the grant date, such that the RSUs are fully vested on the fourth anniversary of the grant date.

F2 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

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April 15, 2021 Filed Apr 19, 2021 21:17 UTC
Bedrosian Camille LEVP and Chief Medical Officer
Exercise / conversionStock Option · Derivative 5,000 $0.00 Strike: $55.00 $0.00
Disclosure

SEC source: 0001209191-21-027329 · doc4.xml · derivative · entry 3

Bedrosian Camille L · CIK 0001326969 · EVP and Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 58,000

Underlying: Common Stock · 5,000 shares

Expires 2028-01-30

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: The option vested with respect to 1/4th of the shares on January 30, 2019 (the first anniversary of the grant date of the option or the "Option Anniversary Date") and 1/48th of the shares initially subject to the option continued to vest on each month as measured from the Option Anniversary Date such that the option will fully vest on the fourth anniversary of the grant date.

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April 15, 2021 Filed Apr 19, 2021 21:17 UTC
Bedrosian Camille LEVP and Chief Medical Officer
SaleCommon Stock 5,000 $109.09 $545,450.00
Disclosure

SEC source: 0001209191-21-027329 · doc4.xml · nonDerivative · entry 2

Bedrosian Camille L · CIK 0001326969 · EVP and Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,139

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $107.35 to $110.12 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

F3 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

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April 15, 2021 Filed Apr 19, 2021 21:17 UTC
Bedrosian Camille LEVP and Chief Medical Officer
Exercise / conversionCommon Stock 5,000 $55.00 $275,000.00
Disclosure

SEC source: 0001209191-21-027329 · doc4.xml · nonDerivative · entry 1

Bedrosian Camille L · CIK 0001326969 · EVP and Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 44,139

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported on this Form 4 were effected pursuant to a trading plan adopted by the Reporting Person pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

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March 08, 2021 Filed Mar 9, 2021 17:37 UTC
Huizenga Theodore AlanSVP, Controller and PAO
SaleCommon Stock 3,000 $120.69 $362,070.00
Disclosure

SEC source: 0001209191-21-018872 · doc4.xml · nonDerivative · entry 1

Huizenga Theodore Alan · CIK 0001603347 · SVP, Controller and PAO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,544

F1 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $120.68 to $120.96 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

F2 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

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March 02, 2021 Filed Mar 4, 2021 01:42 UTC
Harris ErikEVP & Chief Commercial Officer
SaleCommon Stock 707 $138.16 $97,679.12
Disclosure

SEC source: 0001209191-21-017554 · doc4.xml · nonDerivative · entry 4

Harris Erik · CIK 0001780113 · EVP & Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,813

F5 · kind: The sales reported on this row were effected pursuant to a trading plan adopted by the Reporting Person pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F6 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

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March 01, 2021 Filed Mar 4, 2021 01:55 UTC GrantStock Option (Right to Buy) · Derivative 11,000 $0.00 Strike: $142.47 $0.00
Disclosure

SEC source: 0001209191-21-017567 · doc4.xml · derivative · entry 4

Kassberg Thomas Richard · CIK 0001303811 · CBO & EVP

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,000

Underlying: Common Stock · 11,000 shares

Expires 2031-03-01

F7 · derivative.exercise_date: On the first anniversary of the grant date of the option (the "Option Anniversary Date"), 1/4th of the shares initially subject to the option shall vest; thereafter, 1/48th of the shares initially subject to the option shall vest on each month as measured from the Option Anniversary Date.

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March 01, 2021 Filed Mar 4, 2021 01:55 UTC SaleCommon Stock 4,572 $138.17 $631,713.24
Disclosure

SEC source: 0001209191-21-017567 · doc4.xml · nonDerivative · entry 3

Kassberg Thomas Richard · CIK 0001303811 · CBO & EVP

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 107,181

F3 · kind: Represents shares sold to pay required tax withholdings due to the vesting of RSUs.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $138.16 to $138.17 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

F5 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

F6 · balance_after: Includes 139 shares acquired under the Company's 2014 Employee Stock Purchase Plan on October 31, 2020.

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March 01, 2021 Filed Mar 4, 2021 01:55 UTC GrantCommon Stock 4,636 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-017567 · doc4.xml · nonDerivative · entry 2

Kassberg Thomas Richard · CIK 0001303811 · CBO & EVP

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 111,614

F2 · shares: Represents 1,530 shares of common stock and 3,106 RSUs into which previously granted performance stock units were converted on March 1, 2021 upon certification of the performance metric. The RSUs will fully vest on March 1, 2022.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.