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Ultragenyx Pharmaceutical Inc.

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Tapewire entity
4337
SEC CIK
0001515673
Parsed reports
478

Last 12 months

Inside the activity.

0 purchase rows · 27 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202500
Dec 202502
Jan 202601
Feb 202601
Mar 2026011
Apr 202601
May 202603
Jun 202603
Jul 202601
Aug 202602
Sep 202602
Oct 202600

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
March 02, 2026 Filed Mar 3, 2026 23:51 UTC
Huizenga Theodore AlanSVP, Chief Accounting Officer
Tax withholdingCommon Stock 148 $23.39 $3,461.72
Disclosure

SEC source: 0001193125-26-089109 · ownership.xml · nonDerivative · entry 1

Huizenga Theodore Alan · CIK 0001603347 · SVP, Chief Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 50,302

F1 · shares: Represents shares surrendered to the Issuer by the Reporting Person to pay required tax withholdings due to the vesting of RSUs.

Read SEC document
March 02, 2026 Filed Mar 3, 2026 23:50 UTC
Horn HowardChief Financial Officer
SaleCommon Stock 3,119 $22.54 $70,302.26
Disclosure

SEC source: 0001193125-26-089107 · ownership.xml · nonDerivative · entry 3

Horn Howard · CIK 0001786335 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 86,669

Read SEC document
March 02, 2026 Filed Mar 3, 2026 23:50 UTC
Horn HowardChief Financial Officer
SaleCommon Stock 5,290 $22.80 $120,612.00
Disclosure

SEC source: 0001193125-26-089107 · ownership.xml · nonDerivative · entry 2

Horn Howard · CIK 0001786335 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 89,788

F2 · shares: Represents shares sold to pay required tax withholdings due to the vesting of RSUs.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $22.54 to $23.11 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range

Read SEC document
March 02, 2026 Filed Mar 3, 2026 23:49 UTC
Crombez EricEVP and Chief Medical Officer
SaleCommon Stock 7,029 $22.80 $160,261.20
Disclosure

SEC source: 0001193125-26-089104 · ownership.xml · nonDerivative · entry 2

Crombez Eric · CIK 0001653052 · EVP and Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 76,301

F2 · shares: Represents shares sold to pay required tax withholdings due to the vesting of RSUs.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $22.54 to $23.11 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range

F4 · balance_after: Includes 157 shares acquired on October 30, 2025 under the Company's Amended and Restated Employee Stock Purchase Plan

F5 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

Read SEC document
March 02, 2026 Filed Mar 3, 2026 23:49 UTC Tax withholdingCommon Stock 999 $23.39 $23,366.61
Disclosure

SEC source: 0001193125-26-089102 · ownership.xml · nonDerivative · entry 2

Huang Dennis Karl · CIK 0001641217 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 124,729

F2 · shares: Represents shares surrendered to the Issuer by the Reporting Person to pay required tax withholdings due to the vesting of RSUs.

F3 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

Read SEC document
March 01, 2026 Filed Mar 4, 2026 00:06 UTC
KAKKIS EMIL DDirector · President & CEO
GrantCommon Stock 71,177 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-089278 · ownership.xml · nonDerivative · entry 1

KAKKIS EMIL D · CIK 0001248093 · Director · President & CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 712,908

F1 · shares: Represents shares of common stock which previously granted performance stock units were converted on March 1, 2026 upon certification of the performance metrics.

Read SEC document
March 01, 2026 Filed Mar 4, 2026 00:08 UTC
Harris ErikEVP & Chief Commercial Officer
GrantCommon Stock 11,643 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-089282 · ownership.xml · nonDerivative · entry 1

Harris Erik · CIK 0001780113 · EVP & Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 99,498

F1 · shares: Represents shares of common stock which previously granted performance stock units were converted on March 1, 2026 upon certification of the performance metrics.

Read SEC document
March 01, 2026 Filed Mar 4, 2026 00:09 UTC GrantCommon Stock 11,137 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-089287 · ownership.xml · nonDerivative · entry 1

Pinion John Richard · CIK 0001648096 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 119,565

F1 · shares: Represents shares of common stock which previously granted performance stock units were converted on March 1, 2026 upon certification of the performance metrics.

Read SEC document
March 01, 2026 Filed Mar 3, 2026 23:51 UTC
Parschauer Karah HerdmanEVP and Chief Legal Officer
GrantCommon Stock 11,137 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-089111 · ownership.xml · nonDerivative · entry 1

Parschauer Karah Herdman · CIK 0001677455 · EVP and Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 84,408

F1 · shares: Represents shares of common stock which previously granted performance stock units were converted on March 1, 2026 upon certification of the performance metrics.

Read SEC document
March 01, 2026 Filed Mar 3, 2026 23:50 UTC
Horn HowardChief Financial Officer
GrantCommon Stock 6,143 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-089107 · ownership.xml · nonDerivative · entry 1

Horn Howard · CIK 0001786335 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 95,078

F1 · shares: Represents shares of common stock which previously granted performance stock units were converted on March 1, 2026 upon certification of the performance metric.

Read SEC document
March 01, 2026 Filed Mar 3, 2026 23:49 UTC
Crombez EricEVP and Chief Medical Officer
GrantCommon Stock 11,643 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-089104 · ownership.xml · nonDerivative · entry 1

Crombez Eric · CIK 0001653052 · EVP and Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 83,173

F1 · shares: Represents shares of common stock which previously granted performance stock units were converted on March 1, 2026 upon certification of the performance metrics.

Read SEC document
March 01, 2026 Filed Mar 3, 2026 23:49 UTC GrantCommon Stock 11,137 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-089102 · ownership.xml · nonDerivative · entry 1

Huang Dennis Karl · CIK 0001641217 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 125,728

F1 · shares: Represents shares of common stock which previously granted performance stock units were converted on March 1, 2026 upon certification of the performance metric.

Read SEC document
February 02, 2026 Filed Feb 3, 2026 17:00 UTC
Horn HowardChief Financial Officer
SaleCommon Stock 3,061 $23.56 $72,117.16
Disclosure

SEC source: 0001193125-26-034832 · ownership.xml · nonDerivative · entry 1

Horn Howard · CIK 0001786335 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 88,935

F1 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

Read SEC document
January 02, 2026 Filed Jan 5, 2026 21:07 UTC
Horn HowardChief Financial Officer
SaleCommon Stock 3,150 $22.84 $71,946.00
Disclosure

SEC source: 0001193125-26-002410 · ownership.xml · nonDerivative · entry 1

Horn Howard · CIK 0001786335 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 91,996

F1 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

Read SEC document
December 29, 2025 Filed Dec 30, 2025 18:49 UTC
Huizenga Theodore AlanSVP, Chief Accounting Officer
SaleCommon Stock 85 $34.38 $2,922.30
Disclosure

SEC source: 0001193125-25-336619 · ownership.xml · nonDerivative · entry 1

Huizenga Theodore Alan · CIK 0001603347 · SVP, Chief Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 50,450

F1 · kind: Represents shares sold to pay required tax withholdings due to the vesting of RSUs.

F2 · balance_after: Includes 293 shares acquired under the Company's A&R 2014 Employee Stock Purchase Plan on October 31, 2025.

F3 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

Read SEC document
December 10, 2025 Filed Dec 11, 2025 17:10 UTC
Horn HowardChief Financial Officer
SaleCommon Stock 3,081 $36.38 $112,086.78
Disclosure

SEC source: 0001193125-25-315460 · ownership.xml · nonDerivative · entry 1

Horn Howard · CIK 0001786335 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 95,146

F1 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

Read SEC document
October 13, 2025 Filed Oct 14, 2025 16:15 UTC
Horn HowardChief Financial Officer
SaleCommon Stock 7,942 $31.51 $250,252.42
Disclosure

SEC source: 0001193125-25-238708 · ownership.xml · nonDerivative · entry 1

Horn Howard · CIK 0001786335 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 98,227

F1 · shares: Represents shares sold to pay required tax withholdings due to the vesting of RSUs.

F2 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

Read SEC document
September 18, 2025 Filed Sep 19, 2025 22:23 UTC
Huizenga Theodore AlanSVP, Chief Accounting Officer
SaleCommon Stock 64 $29.17 $1,866.88
Disclosure

SEC source: 0001193125-25-209387 · ownership.xml · nonDerivative · entry 1

Huizenga Theodore Alan · CIK 0001603347 · SVP, Chief Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 50,242

F1 · kind: Represents shares sold to pay required tax withholdings due to the vesting of RSUs.

F2 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

Read SEC document
September 12, 2025 Filed Sep 12, 2025 20:11 UTC
Parschauer Karah HerdmanEVP and Chief Legal Officer
SaleCommon Stock 2,450 $31.17 $76,366.50
Disclosure

SEC source: 0001677455-25-000005 · ownership.xml · nonDerivative · entry 1

Parschauer Karah Herdman · CIK 0001677455 · EVP and Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 73,271

F1 · balance_after: Includes 434 shares acquired under the Company's A&R 2014 Employee Stock Purchase Plan on April 30, 2025.

F2 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

Read SEC document
September 05, 2025 Filed Sep 8, 2025 18:01 UTC
Huizenga Theodore AlanSVP, Chief Accounting Officer
SaleCommon Stock 84 $31.39 $2,636.76
Disclosure

SEC source: 0000950170-25-113446 · ownership.xml · nonDerivative · entry 1

Huizenga Theodore Alan · CIK 0001603347 · SVP, Chief Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 50,306

F1 · shares: Represents shares sold to pay required tax withholdings due to the vesting of RSUs.

F2 · balance_after: Includes 266 shares acquired under the Company's A&R 2014 Employee Stock Purchase Plan on April 30, 2025.

F3 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

Read SEC document
June 20, 2025 Filed Jun 23, 2025 17:50 UTC SaleCommon Stock 2,405 $37.39 $89,922.95
Disclosure

SEC source: 0000950170-25-088878 · ownership.xml · nonDerivative · entry 1

Sanders Corazon (Corsee) D. · CIK 0001796536 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 15,344

Read SEC document
May 15, 2025 Filed May 19, 2025 18:31 UTC
Ray AmritDirector
GrantStock Option (Right to Buy) · Derivative 10,787 $0.00 Strike: $34.84 $0.00
Disclosure

SEC source: 0000950170-25-074661 · ownership.xml · derivative · entry 2

Ray Amrit · CIK 0001924797 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,787

Underlying: Common Stock · 10,787 shares

Expires 2035-05-15

F2 · derivative.exercise_date: The option shall vest in full on the earlier of (i) the Company's next Annual Meeting of Stockholders or (ii) May 15, 2026.

Read SEC document
May 15, 2025 Filed May 19, 2025 18:31 UTC
Ray AmritDirector
GrantCommon Stock 5,740 $0.00 $0.00
Disclosure

SEC source: 0000950170-25-074661 · ownership.xml · nonDerivative · entry 1

Ray Amrit · CIK 0001924797 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 23,365

F1 · shares: Award of Restricted Stock Units ("RSUs") under the Company's 2023 Incentive Plan. The RSUs shall vest in full on the earlier of (i) the Company's next Annual Meeting of Stockholders or (ii) May 15, 2026.

Read SEC document
May 15, 2025 Filed May 19, 2025 22:33 UTC GrantStock Option (Right to Buy) · Derivative 10,787 $0.00 Strike: $34.84 $0.00
Disclosure

SEC source: 0000950170-25-074667 · ownership.xml · derivative · entry 2

WELCH DANIEL G · CIK 0001206199 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,787

Underlying: Common Stock · 10,787 shares

Expires 2035-05-15

F2 · derivative.exercise_date: The option shall vest in full on the earlier of (i) the Company's next Annual Meeting of Stockholders or (ii) May 15, 2026.

Read SEC document
May 15, 2025 Filed May 19, 2025 22:33 UTC GrantCommon Stock 5,740 $0.00 $0.00
Disclosure

SEC source: 0000950170-25-074667 · ownership.xml · nonDerivative · entry 1

WELCH DANIEL G · CIK 0001206199 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 32,690

F1 · shares: Award of Restricted Stock Units ("RSUs") under the Company's 2023 Incentive Plan. The RSUs shall vest in full on the earlier of (i) the Company's next Annual Meeting of Stockholders or (ii) May 15, 2026.

Read SEC document
May 15, 2025 Filed May 19, 2025 22:31 UTC GrantStock Option (Right to Buy) · Derivative 10,787 $0.00 Strike: $34.84 $0.00
Disclosure

SEC source: 0000950170-25-074662 · ownership.xml · derivative · entry 2

Dunsire Deborah · CIK 0001332764 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,787

Underlying: Common Stock · 10,787 shares

Expires 2035-05-15

F2 · derivative.exercise_date: The option shall vest in full on the earlier of (i) the Company's next Annual Meeting of Stockholders or (ii) May 15, 2026.

Read SEC document
May 15, 2025 Filed May 19, 2025 22:31 UTC GrantCommon Stock 5,740 $0.00 $0.00
Disclosure

SEC source: 0000950170-25-074662 · ownership.xml · nonDerivative · entry 1

Dunsire Deborah · CIK 0001332764 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 30,815

F1 · shares: Award of Restricted Stock Units ("RSUs") under the Company's 2023 Incentive Plan. The RSUs shall vest in full on the earlier of (i) the Company's next Annual Meeting of Stockholders or (ii) May 15, 2026.

Read SEC document
May 15, 2025 Filed May 19, 2025 18:32 UTC GrantStock Option (Right to Buy) · Derivative 10,787 $0.00 Strike: $34.84 $0.00
Disclosure

SEC source: 0000950170-25-074665 · ownership.xml · derivative · entry 2

NARACHI MICHAEL · CIK 0001380022 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,787

Underlying: Common Stock · 10,787 shares

Expires 2035-05-15

F2 · derivative.exercise_date: The option shall vest in full on the earlier of (i) the Company's next Annual Meeting of Stockholders or (ii) May 15, 2026.

Read SEC document
May 15, 2025 Filed May 19, 2025 18:32 UTC GrantCommon Stock 5,740 $0.00 $0.00
Disclosure

SEC source: 0000950170-25-074665 · ownership.xml · nonDerivative · entry 1

NARACHI MICHAEL · CIK 0001380022 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 32,690

F1 · shares: Award of Restricted Stock Units ("RSUs") under the Company's 2023 Incentive Plan. The RSUs shall vest in full on the earlier of (i) the Company's next Annual Meeting of Stockholders or (ii) May 15, 2026.

Read SEC document
May 15, 2025 Filed May 19, 2025 22:32 UTC GrantStock Option (Right to Buy) · Derivative 10,787 $0.00 Strike: $34.84 $0.00
Disclosure

SEC source: 0000950170-25-074664 · ownership.xml · derivative · entry 2

Fust Matthew K · CIK 0001397266 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,787

Underlying: Common Stock · 10,787 shares

Expires 2035-05-15

F2 · derivative.exercise_date: The option shall vest in full on the earlier of (i) the Company's next Annual Meeting of Stockholders or (ii) May 15, 2026.

Read SEC document
May 15, 2025 Filed May 19, 2025 22:32 UTC GrantCommon Stock 5,740 $0.00 $0.00
Disclosure

SEC source: 0000950170-25-074664 · ownership.xml · nonDerivative · entry 1

Fust Matthew K · CIK 0001397266 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 25,945

F1 · shares: Award of Restricted Stock Units ("RSUs") under the Company's 2023 Incentive Plan. The RSUs shall vest in full on the earlier of (i) the Company's next Annual Meeting of Stockholders or (ii) May 15, 2026.

Read SEC document
May 15, 2025 Filed May 19, 2025 22:34 UTC GrantStock Option (Right to Buy) · Derivative 10,787 $0.00 Strike: $34.84 $0.00
Disclosure

SEC source: 0000950170-25-074669 · ownership.xml · derivative · entry 2

SULIMAN SHEHNAAZ · CIK 0001713070 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,787

Underlying: Common Stock · 10,787 shares

Expires 2035-05-15

F2 · derivative.exercise_date: The option shall vest in full on the earlier of (i) the Company's next Annual Meeting of Stockholders or (ii) May 15, 2026.

Read SEC document
May 15, 2025 Filed May 19, 2025 22:34 UTC GrantCommon Stock 5,740 $0.00 $0.00
Disclosure

SEC source: 0000950170-25-074669 · ownership.xml · nonDerivative · entry 1

SULIMAN SHEHNAAZ · CIK 0001713070 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 25,940

F1 · shares: Award of Restricted Stock Units ("RSUs") under the Company's 2023 Incentive Plan. The RSUs shall vest in full on the earlier of (i) the Company's next Annual Meeting of Stockholders or (ii) May 15, 2026.

Read SEC document
May 15, 2025 Filed May 19, 2025 22:33 UTC GrantStock Option (Right to Buy) · Derivative 10,787 $0.00 Strike: $34.84 $0.00
Disclosure

SEC source: 0000950170-25-074666 · ownership.xml · derivative · entry 2

Sanders Corazon (Corsee) D. · CIK 0001796536 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,787

Underlying: Common Stock · 10,787 shares

Expires 2035-05-15

F2 · derivative.exercise_date: The option shall vest in full on the earlier of (i) the Company's next Annual Meeting of Stockholders or (ii) May 15, 2026.

Read SEC document
May 15, 2025 Filed May 19, 2025 22:33 UTC GrantCommon Stock 5,740 $0.00 $0.00
Disclosure

SEC source: 0000950170-25-074666 · ownership.xml · nonDerivative · entry 1

Sanders Corazon (Corsee) D. · CIK 0001796536 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 17,749

F1 · shares: Award of Restricted Stock Units ("RSUs") under the Company's 2023 Incentive Plan. The RSUs shall vest in full on the earlier of (i) the Company's next Annual Meeting of Stockholders or (ii) May 15, 2026.

Read SEC document
May 05, 2025 Filed May 5, 2025 23:18 UTC
Crombez EricEVP and Chief Medical Officer
SaleCommon Stock 520 $39.24 $20,404.80
Disclosure

SEC source: 0000950170-25-063792 · ownership.xml · nonDerivative · entry 2

Crombez Eric · CIK 0001653052 · EVP and Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 71,530

F1 · shares: Represents shares sold to pay required tax withholdings due to the vesting of RSUs.

F2 · balance_after: Includes 370 shares acquired on April 30, 2025 under the Company's Amended and Restated Employee Stock Purchase Plan

F3 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

Read SEC document
April 21, 2025 Filed May 5, 2025 23:18 UTC
Crombez EricEVP and Chief Medical Officer
SaleCommon Stock 242 $35.11 $8,496.62
Disclosure

SEC source: 0000950170-25-063792 · ownership.xml · nonDerivative · entry 1

Crombez Eric · CIK 0001653052 · EVP and Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 71,680

F1 · shares: Represents shares sold to pay required tax withholdings due to the vesting of RSUs.

Read SEC document
March 06, 2025 Filed Mar 10, 2025 16:53 UTC
Horn HowardChief Financial Officer
SaleCommon Stock 1,785 $40.40 $72,114.00
Disclosure

SEC source: 0000950170-25-036056 · ownership.xml · nonDerivative · entry 1

Horn Howard · CIK 0001786335 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 106,169

F1 · shares: Represents shares sold to pay required tax withholdings due to the vesting of RSUs.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $39.73 to $41.37 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

F3 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

Read SEC document
March 03, 2025 Filed Mar 5, 2025 01:19 UTC Tax withholdingCommon Stock 508 $42.92 $21,803.36
Disclosure

SEC source: 0000950170-25-032802 · ownership.xml · nonDerivative · entry 3

Kassberg Thomas Richard · CIK 0001303811 · CBO & EVP

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 264,730

F4 · shares: Represents shares surrendered to the Issuer by the Reporting Person to pay required tax withholdings due to the vesting of RSUs.

F5 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

Read SEC document
March 03, 2025 Filed Mar 5, 2025 01:19 UTC SaleCommon Stock 6,028 $42.10 $253,778.80
Disclosure

SEC source: 0000950170-25-032802 · ownership.xml · nonDerivative · entry 2

Kassberg Thomas Richard · CIK 0001303811 · CBO & EVP

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 265,238

F2 · shares: Represents shares sold to pay required tax withholdings due to the vesting of RSUs.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $41.77 to $42.90 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
March 03, 2025 Filed Mar 5, 2025 01:10 UTC
KAKKIS EMIL DDirector · President & CEO
SaleCommon Stock 73,434 $42.10 $3,091,571.40
Disclosure

SEC source: 0000950170-25-032779 · ownership.xml · nonDerivative · entry 3

KAKKIS EMIL D · CIK 0001248093 · Director · President & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 641,731

F3 · shares: Represents shares sold to pay required tax withholdings due to the vesting of RSUs.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $41.77 to $42.90 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

F7 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

Read SEC document
March 03, 2025 Filed Mar 5, 2025 01:18 UTC
Parschauer Karah HerdmanEVP and Chief Legal Officer
SaleCommon Stock 12,846 $42.10 $540,816.60
Disclosure

SEC source: 0000950170-25-032798 · ownership.xml · nonDerivative · entry 2

Parschauer Karah Herdman · CIK 0001677455 · EVP and Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 75,287

F2 · shares: Represents shares sold to pay required tax withholdings due to the vesting of RSUs.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $41.77 to $42.90 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

F4 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

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March 03, 2025 Filed Mar 5, 2025 01:16 UTC
Crombez EricEVP and Chief Medical Officer
SaleCommon Stock 8,945 $42.10 $376,584.50
Disclosure

SEC source: 0000950170-25-032794 · ownership.xml · nonDerivative · entry 3

Crombez Eric · CIK 0001653052 · EVP and Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 71,922

F3 · shares: Represents shares sold to pay required tax withholdings due to the vesting of RSUs.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $41.77 to $42.90 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

F5 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

F6 · balance_after: Includes 652 shares acquired on April 30, 2024 and October 31, 2024 under the Company's Amended and Restated Employee Stock Purchase Plan

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March 03, 2025 Filed Mar 5, 2025 01:12 UTC Tax withholdingCommon Stock 31 $42.92 $1,330.52
Disclosure

SEC source: 0000950170-25-032785 · ownership.xml · nonDerivative · entry 4

Pinion John Richard · CIK 0001648096 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 108,428

F5 · shares: Represents shares surrendered to the Issuer by the Reporting Person to pay required tax withholdings due to the vesting of RSUs.

F6 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

F7 · balance_after: Includes 693 shares acquired under the Company's Amended & Restated Employee Stock Purchase Plan on April 30, 2024

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March 03, 2025 Filed Mar 5, 2025 01:12 UTC SaleCommon Stock 14,439 $42.10 $607,881.90
Disclosure

SEC source: 0000950170-25-032785 · ownership.xml · nonDerivative · entry 3

Pinion John Richard · CIK 0001648096 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 107,766

F3 · shares: Represents shares sold to pay required tax withholdings due to the vesting of RSUs.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $41.77 to $42.90 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

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March 03, 2025 Filed Mar 5, 2025 01:06 UTC
Harris ErikEVP & Chief Commercial Officer
SaleCommon Stock 15,103 $42.10 $635,836.30
Disclosure

SEC source: 0000950170-25-032773 · ownership.xml · nonDerivative · entry 3

Harris Erik · CIK 0001780113 · EVP & Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 87,855

F3 · shares: Represents shares sold to pay required tax withholdings due to the vesting of RSUs.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $41.77 to $42.90 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

F5 · balance_after: Includes 539 shares acquired under the Company's Amended & Restated Employee Stock Purchase Plan on April 30, 2024 and October 31, 2024

F6 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

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March 03, 2025 Filed Mar 5, 2025 01:02 UTC Tax withholdingCommon Stock 1,348 $42.92 $57,856.16
Disclosure

SEC source: 0000950170-25-032767 · ownership.xml · nonDerivative · entry 3

Huang Dennis Karl · CIK 0001641217 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 114,591

F3 · shares: Represents shares surrendered to the Issuer by the Reporting Person to pay required tax withholdings due to the vesting of RSUs.

F4 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

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March 03, 2025 Filed Mar 5, 2025 01:00 UTC
Huizenga Theodore AlanSVP, Chief Accounting Officer
Tax withholdingCommon Stock 141 $42.92 $6,051.72
Disclosure

SEC source: 0000950170-25-032764 · ownership.xml · nonDerivative · entry 3

Huizenga Theodore Alan · CIK 0001603347 · SVP, Chief Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 50,124

F4 · shares: Represents shares surrendered to the Issuer by the Reporting Person to pay required tax withholdings due to the vesting of RSUs.

F5 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

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March 03, 2025 Filed Mar 5, 2025 01:00 UTC
Huizenga Theodore AlanSVP, Chief Accounting Officer
SaleCommon Stock 967 $42.10 $40,710.70
Disclosure

SEC source: 0000950170-25-032764 · ownership.xml · nonDerivative · entry 2

Huizenga Theodore Alan · CIK 0001603347 · SVP, Chief Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 50,265

F2 · shares: Represents shares sold to pay required tax withholdings due to the vesting of RSUs.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $41.77 to $42.90 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

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March 01, 2025 Filed Mar 3, 2025 18:58 UTC
Parschauer Karah HerdmanEVP and Chief Legal Officer
GrantStock Option (Right to Buy) · Derivative 26,074 $0.00 Strike: $42.92 $0.00
Disclosure

SEC source: 0000950170-25-030639 · ownership.xml · derivative · entry 4

Parschauer Karah Herdman · CIK 0001677455 · EVP and Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 26,074

Underlying: Common Stock · 26,074 shares

Expires 2035-03-01

F4 · derivative.exercise_date: On the first anniversary of the grant date of the option (the "Option Anniversary Date"), 1/4th of the shares initially subject to the option shall vest; thereafter, 1/48th of the shares initially subject to the option shall vest on each month as measured from the Option Anniversary Date.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.