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Nasdaq · USD

PTGX

Protagonist Therapeutics, Inc

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3552
SEC CIK
0001377121
Parsed reports
275

Last 12 months

Inside the activity.

0 purchase rows · 37 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202501
Dec 202500
Jan 2026012
Feb 202602
Mar 202605
Apr 202601
May 202607
Jun 202602
Jul 202600
Aug 202602
Sep 202605
Oct 202600

Latest available

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
November 26, 2019 Filed Nov 27, 2019 19:58 UTC
PATEL DINESH V PH DDirector · President and CEO
Exercise / conversionCommon Stock 4,000 $1.16 $4,640.00
Disclosure

SEC source: 0001209191-19-058295 · doc4.xml · nonDerivative · entry 1

PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 379,824

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · balance_after: Includes 1,032 shares acquired by the Reporting Person under the Issuer's 2016 Employee Stock Purchase Plan on September 9, 2019.

Read SEC document
August 15, 2019 Filed Apr 8, 2020 17:46 UTC GrantStock Option (right to buy) · Derivative 5,000 $0.00 Strike: $9.99 $0.00
Disclosure

SEC source: 0001209191-20-023949 · doc4.xml · derivative · entry 1

KHOSLA CHAITAN PHD · CIK 0001135139 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,000

Underlying: Common Stock · 5,000 shares

Expires 2029-08-14

Read SEC document
August 06, 2019 Filed Aug 8, 2019 22:15 UTC
PATEL DINESH V PH DDirector · President and CEO
SaleCommon Stock 10,792 $8.85 $95,535.10
Disclosure

SEC source: 0001209191-19-045195 · doc4.xml · nonDerivative · entry 1

PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 374,792

F1 · kind: The sales reported on this Form 4 represent shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of Restricted Stock Units. These sales are mandated by the Issuer's election under its equity incentive plans to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and do not represent discretionary trades by the Reporting Person.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $8.80 to $9.2504, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

F3 · balance_after: Includes 1,753 shares acquired by the Reporting Person under the Issuer's 2016 Employee Stock Purchase Plan on March 8, 2019.

Read SEC document
August 06, 2019 Filed Aug 8, 2019 22:17 UTC
Liu David YChief Scientific Officer
SaleCommon Stock 3,395 $8.85 $30,044.05
Disclosure

SEC source: 0001209191-19-045196 · doc4.xml · nonDerivative · entry 1

Liu David Y · CIK 0001675881 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 49,802

F1 · kind: The sales reported on this Form 4 represent shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of Restricted Stock Units. These sales are mandated by the Issuer's election under its equity incentive plans to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and do not represent discretionary trades by the Reporting Person.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $8.80 to $9.2255, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

F3 · balance_after: Includes 2,000 shares acquired by the Reporting Person under the Issuer's 2016 Employee Stock Purchase Plan on March 8, 2019.

Read SEC document
June 07, 2019 Filed Jun 11, 2019 18:26 UTC GrantStock Option (right to buy) · Derivative 12,000 $0.00 Strike: $11.80 $0.00
Disclosure

SEC source: 0001209191-19-036203 · doc4.xml · derivative · entry 1

KHOSLA CHAITAN PHD · CIK 0001135139 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,000

Underlying: Common Stock · 12,000 shares

Expires 2029-06-06

F1 · derivative.exercise_date: The shares subject to this option shall vest at the earlier of (i) June 7, 2020, or (ii) the date of the 2020 Annual Meeting of stockholders of the Issuer, subject to the non-employee director's continuous service with the Issuer through such dates. The shares subject to this option will vest in full upon completion of a Change in Control (as defined in the Issuer's 2016 Equity Incentive Plan).

Read SEC document
June 07, 2019 Filed Jun 11, 2019 18:28 UTC GrantStock Option (right to buy) · Derivative 12,000 $0.00 Strike: $11.80 $0.00
Disclosure

SEC source: 0001209191-19-036204 · doc4.xml · derivative · entry 1

Noonberg Sarah B. · CIK 0001706301 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,000

Underlying: Common Stock · 12,000 shares

Expires 2029-06-06

F1 · derivative.exercise_date: The shares subject to this option shall vest at the earlier of (i) June 7, 2020, or (ii) the date of the 2020 Annual Meeting of stockholders of the Issuer, subject to the non-employee director's continuous service with the Issuer through such dates. The shares subject to this option will vest in full upon completion of a Change in Control (as defined in the Issuer's 2016 Equity Incentive Plan).

Read SEC document
June 07, 2019 Filed Jun 11, 2019 22:33 UTC GrantStock Option (right to buy) · Derivative 12,000 $0.00 Strike: $11.80 $0.00
Disclosure

SEC source: 0001209191-19-036214 · doc4.xml · derivative · entry 1

Waddill William D. · CIK 0001553338 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,000

Underlying: Common Stock · 12,000 shares

Expires 2029-06-06

F1 · derivative.exercise_date: The shares subject to this option shall vest at the earlier of (i) June 7, 2020, or (ii) the date of the 2020 Annual Meeting of stockholders of the Issuer, subject to the non-employee director's continuous service with the Issuer through such dates. The shares subject to this option will vest in full upon completion of a Change in Control (as defined in the Issuer's 2016 Equity Incentive Plan).

Read SEC document
June 07, 2019 Filed Jun 11, 2019 22:31 UTC GrantStock Option (right to buy) · Derivative 12,000 $0.00 Strike: $11.80 $0.00
Disclosure

SEC source: 0001209191-19-036211 · doc4.xml · derivative · entry 1

Williams Lewis T · CIK 0001475714 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,000

Underlying: Common Stock · 12,000 shares

Expires 2029-06-06

F1 · derivative.exercise_date: The shares subject to this option shall vest at the earlier of (i) June 7, 2020, or (ii) the date of the 2020 Annual Meeting of stockholders of the Issuer, subject to the non-employee director's continuous service with the Issuer through such dates. The shares subject to this option will vest in full upon completion of a Change in Control (as defined in the Issuer's 2016 Equity Incentive Plan).

Read SEC document
June 07, 2019 Filed Jun 11, 2019 22:29 UTC GrantStock Option (right to buy) · Derivative 12,000 $0.00 Strike: $11.80 $0.00
Disclosure

SEC source: 0001209191-19-036207 · doc4.xml · derivative · entry 1

SELICK HAROLD E · CIK 0001287233 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,000

Underlying: Common Stock · 12,000 shares

Expires 2029-06-06

F1 · derivative.exercise_date: The shares subject to this option shall vest at the earlier of (i) June 7, 2020, or (ii) the date of the 2020 Annual Meeting of stockholders of the Issuer, subject to the non-employee director's continuous service with the Issuer through such dates. The shares subject to this option will vest in full upon completion of a Change in Control (as defined in the Issuer's 2016 Equity Incentive Plan).

Read SEC document
June 07, 2019 Filed Jun 11, 2019 22:20 UTC GrantStock Option (right to buy) · Derivative 12,000 $0.00 Strike: $11.80 $0.00
Disclosure

SEC source: 0001209191-19-036195 · doc4.xml · derivative · entry 1

Giraudo Bryan · CIK 0001740847 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,000

Underlying: Common Stock · 12,000 shares

Expires 2029-06-06

F1 · derivative.exercise_date: The shares subject to this option shall vest at the earlier of (i) June 7, 2020, or (ii) the date of the 2020 Annual Meeting of stockholders of the Issuer, subject to the non-employee director's continuous service with the Issuer through such dates. The shares subject to this option will vest in full upon completion of a Change in Control (as defined in the Issuer's 2016 Equity Incentive Plan).

Read SEC document
May 31, 2019 Filed Jun 3, 2019 23:40 UTC
Kalkofen Donald A.Chief Financial Officer
GrantStock Option (right to buy) · Derivative 100,000 $0.00 Strike: $10.06 $0.00
Disclosure

SEC source: 0001209191-19-034082 · doc4.xml · derivative · entry 1

Kalkofen Donald A. · CIK 0001771066 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 100,000

Underlying: Common Stock · 100,000 shares

Expires 2029-05-30

F1 · derivative.exercise_date: This option vests over a four-year period with 25% of the shares underlying the option vesting on the one-year anniversary of the vesting commencement date of May 28, 2019, and the balance vesting in equal monthly installments over the following 36 months.

Read SEC document
May 15, 2019 Filed May 16, 2019 22:43 UTC
Saks Samuel RChief Medical Officer
GrantStock Option (right to buy) · Derivative 45,000 $0.00 Strike: $10.80 $0.00
Disclosure

SEC source: 0001209191-19-030616 · doc4.xml · derivative · entry 1

Saks Samuel R · CIK 0001365615 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,000

Underlying: Common Stock · 45,000 shares

Expires 2029-05-14

F1 · derivative.exercise_date: The stock option vests in 48 equal monthly installments following the date of grant.

Read SEC document
April 01, 2019 Filed Apr 2, 2019 23:19 UTC Exercise / conversionStock Option (right to buy) · Derivative 3,310 $0.00 Strike: $1.31 $0.00
Disclosure

SEC source: 0001209191-19-022784 · doc4.xml · derivative · entry 2

SELICK HAROLD E · CIK 0001287233 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 3,310 shares

Expires 2019-05-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: The stock option vested in 36 equal monthly installments following the vesting commencement date.

Read SEC document
April 01, 2019 Filed Apr 2, 2019 23:19 UTC Exercise / conversionCommon Stock 3,310 $1.31 $4,336.10
Disclosure

SEC source: 0001209191-19-022784 · doc4.xml · nonDerivative · entry 1

SELICK HAROLD E · CIK 0001287233 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,310

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
March 01, 2019 Filed Mar 4, 2019 23:33 UTC
PATEL DINESH V PH DDirector · President and CEO
SaleCommon Stock 2,183 $8.03 $17,529.49
Disclosure

SEC source: 0001209191-19-015935 · doc4.xml · nonDerivative · entry 2

PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 383,831

F2 · kind: The sales reported on this Form 4 represent shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of Restricted Stock Units. These sales are mandated by the Issuer's election under its equity incentive plans to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and do not represent discretionary trades by the Reporting Person.

Read SEC document
March 01, 2019 Filed Mar 4, 2019 23:35 UTC
Liu David YChief Scientific Officer
SaleCommon Stock 810 $8.03 $6,504.30
Disclosure

SEC source: 0001209191-19-015939 · doc4.xml · nonDerivative · entry 2

Liu David Y · CIK 0001675881 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 51,197

F2 · kind: The sales reported on this Form 4 represent shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of Restricted Stock Units. These sales are mandated by the Issuer's election under its equity incentive plans to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and do not represent discretionary trades by the Reporting Person.

Read SEC document
March 01, 2019 Filed Mar 4, 2019 23:29 UTC
Shames Richard S.Chief Medical Officer
SaleCommon Stock 657 $8.03 $5,275.71
Disclosure

SEC source: 0001209191-19-015927 · doc4.xml · nonDerivative · entry 2

Shames Richard S. · CIK 0001675878 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,021

F2 · kind: The sales reported on this Form 4 represent shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of Restricted Stock Units. These sales are mandated by the Issuer's election under its equity incentive plans to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and do not represent discretionary trades by the Reporting Person.

Read SEC document
February 28, 2019 Filed Mar 4, 2019 23:33 UTC
PATEL DINESH V PH DDirector · President and CEO
GrantStock Option (right to buy) · Derivative 172,500 $0.00 Strike: $8.02 $0.00
Disclosure

SEC source: 0001209191-19-015935 · doc4.xml · derivative · entry 3

PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 172,500

Underlying: Common Stock · 172,500 shares

Expires 2029-02-27

F3 · derivative.exercise_date: The stock option vests in 48 equal monthly installments following the date of grant.

Read SEC document
February 28, 2019 Filed Mar 4, 2019 23:33 UTC
PATEL DINESH V PH DDirector · President and CEO
GrantCommon Stock 28,750 $0.00 $0.00
Disclosure

SEC source: 0001209191-19-015935 · doc4.xml · nonDerivative · entry 1

PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 386,014

F1 · shares: Represents grant of the restricted stock units payable solely in common stock that vest in equal annual installments over four years from the grant date.

Read SEC document
February 28, 2019 Filed Mar 4, 2019 23:32 UTC
Saks Samuel RChief Development Officer
GrantStock Option (right to buy) · Derivative 15,000 $0.00 Strike: $8.02 $0.00
Disclosure

SEC source: 0001209191-19-015930 · doc4.xml · derivative · entry 2

Saks Samuel R · CIK 0001365615 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 15,000 shares

Expires 2029-02-27

F2 · derivative.exercise_date: The stock option vests in 48 equal monthly installments following the date of grant.

Read SEC document
February 28, 2019 Filed Mar 4, 2019 23:32 UTC
Saks Samuel RChief Development Officer
GrantCommon Stock 2,500 $0.00 $0.00
Disclosure

SEC source: 0001209191-19-015930 · doc4.xml · nonDerivative · entry 1

Saks Samuel R · CIK 0001365615 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,500

F1 · shares: Represents grant of the restricted stock units payable solely in common stock that vest in equal annual installments over four years from the grant date.

Read SEC document
February 28, 2019 Filed Mar 4, 2019 23:35 UTC
Liu David YChief Scientific Officer
GrantEmployee Stock Option (right to buy) · Derivative 90,000 $0.00 Strike: $8.02 $0.00
Disclosure

SEC source: 0001209191-19-015939 · doc4.xml · derivative · entry 3

Liu David Y · CIK 0001675881 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 90,000

Underlying: Common Stock · 90,000 shares

Expires 2029-02-27

F3 · derivative.exercise_date: The stock option vests in 48 equal monthly installments following the date of grant.

Read SEC document
February 28, 2019 Filed Mar 4, 2019 23:35 UTC
Liu David YChief Scientific Officer
GrantCommon Stock 15,000 $0.00 $0.00
Disclosure

SEC source: 0001209191-19-015939 · doc4.xml · nonDerivative · entry 1

Liu David Y · CIK 0001675881 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 52,007

F1 · shares: Represents grant of the restricted stock units payable solely in common stock that vest in equal annual installments over four years from the grant date.

Read SEC document
February 28, 2019 Filed Mar 4, 2019 23:29 UTC
Shames Richard S.Chief Medical Officer
GrantStock Option (right to buy) · Derivative 51,000 $0.00 Strike: $8.02 $0.00
Disclosure

SEC source: 0001209191-19-015927 · doc4.xml · derivative · entry 3

Shames Richard S. · CIK 0001675878 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 51,000

Underlying: Common Stock · 51,000 shares

Expires 2029-02-27

F3 · derivative.exercise_date: The stock option vests in 48 equal monthly installments following the date of grant.

Read SEC document
February 28, 2019 Filed Mar 4, 2019 23:29 UTC
Shames Richard S.Chief Medical Officer
GrantCommon Stock 8,500 $0.00 $0.00
Disclosure

SEC source: 0001209191-19-015927 · doc4.xml · nonDerivative · entry 1

Shames Richard S. · CIK 0001675878 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,678

F1 · shares: Represents grant of the restricted stock units payable solely in common stock that vest in equal annual installments over four years from the grant date.

Read SEC document
February 28, 2019 Filed Mar 4, 2019 23:27 UTC
Gupta SuneelEVP Clinical Operations
GrantStock Option (right to buy) · Derivative 45,000 $0.00 Strike: $8.02 $0.00
Disclosure

SEC source: 0001209191-19-015926 · doc4.xml · derivative · entry 2

Gupta Suneel · CIK 0001763923 · EVP Clinical Operations

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,000

Underlying: Common Stock · 45,000 shares

Expires 2029-02-27

F2 · derivative.exercise_date: The stock option vests in 48 equal monthly installments following the date of grant.

Read SEC document
February 28, 2019 Filed Mar 4, 2019 23:27 UTC
Gupta SuneelEVP Clinical Operations
GrantCommon Stock 7,500 $0.00 $0.00
Disclosure

SEC source: 0001209191-19-015926 · doc4.xml · nonDerivative · entry 1

Gupta Suneel · CIK 0001763923 · EVP Clinical Operations

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,500

F1 · shares: Represents grant of the restricted stock units payable solely in common stock that vest in equal annual installments over four years from the grant date.

Read SEC document
February 06, 2019 Filed Feb 8, 2019 22:37 UTC
PATEL DINESH V PH DDirector · President and CEO
SaleCommon Stock 10,132 $7.71 $78,117.72
Disclosure

SEC source: 0001209191-19-008690 · doc4.xml · nonDerivative · entry 2

PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 357,264

F1 · kind: The sales reported on this Form 4 represent shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of Restricted Stock Units. These sales are mandated by the Issuer's election under its equity incentive plans to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and do not represent discretionary trades by the Reporting Person.

Read SEC document
February 06, 2019 Filed Feb 8, 2019 22:37 UTC
PATEL DINESH V PH DDirector · President and CEO
SaleCommon Stock 777 $8.10 $6,292.22
Disclosure

SEC source: 0001209191-19-008690 · doc4.xml · nonDerivative · entry 1

PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 367,396

F1 · kind: The sales reported on this Form 4 represent shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of Restricted Stock Units. These sales are mandated by the Issuer's election under its equity incentive plans to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and do not represent discretionary trades by the Reporting Person.

Read SEC document
February 06, 2019 Filed Feb 8, 2019 22:30 UTC
Liu David YChief Scientific Officer
SaleCommon Stock 3,821 $7.74 $29,561.55
Disclosure

SEC source: 0001209191-19-008679 · doc4.xml · nonDerivative · entry 1

Liu David Y · CIK 0001675881 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 37,007

F1 · kind: The sales reported on this Form 4 represent shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of Restricted Stock Units. These sales are mandated by the Issuer's election under its equity incentive plans to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and do not represent discretionary trades by the Reporting Person.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $7.71 to $8.1377, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
February 06, 2019 Filed Feb 8, 2019 22:27 UTC
Shames Richard S.Chief Medical Officer
SaleCommon Stock 2,580 $7.71 $19,891.80
Disclosure

SEC source: 0001209191-19-008675 · doc4.xml · nonDerivative · entry 2

Shames Richard S. · CIK 0001675878 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,178

F1 · kind: The sales reported on this Form 4 represent shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of Restricted Stock Units. These sales are mandated by the Issuer's election under its equity incentive plans to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and do not represent discretionary trades by the Reporting Person.

Read SEC document
February 06, 2019 Filed Feb 8, 2019 22:27 UTC
Shames Richard S.Chief Medical Officer
SaleCommon Stock 198 $8.15 $1,613.70
Disclosure

SEC source: 0001209191-19-008675 · doc4.xml · nonDerivative · entry 1

Shames Richard S. · CIK 0001675878 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,758

F1 · kind: The sales reported on this Form 4 represent shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of Restricted Stock Units. These sales are mandated by the Issuer's election under its equity incentive plans to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and do not represent discretionary trades by the Reporting Person.

Read SEC document
January 15, 2019 Filed Jan 16, 2019 23:42 UTC
Gupta SuneelEVP Clinical Operations
Exercise / conversionStock Option (right to buy) · Derivative 110,000 $0.00 Strike: $7.38 $0.00
Disclosure

SEC source: 0001209191-19-003994 · doc4.xml · derivative · entry 1

Gupta Suneel · CIK 0001763923 · EVP Clinical Operations

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 110,000

Underlying: Common Stock · 110,000 shares

Expires 2029-01-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: The option vests over a four-year period, with 1/4th of the shares subject to the option vesting on the one year anniversary of the vesting commencement date, and 1/36th of the remaining shares subject to the option vesting each month, subject to the Reporting Person continuing to be a service provider of the Issuer through each such date.

Read SEC document
January 11, 2019 Filed Jan 15, 2019 00:00 UTC
PATEL DINESH V PH DDirector · President and CEO
Exercise / conversionStock Option (right to buy) · Derivative 22,344 $0.00 Strike: $1.16 $0.00
Disclosure

SEC source: 0001209191-19-003606 · doc4.xml · derivative · entry 2

PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,343

Underlying: Common Stock · 22,344 shares

Expires 2025-10-28

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: 1/4th of the shares subject to the option shall vest on the one year anniversary of the vesting commencement date, and 1/36th of the remaining shares subject to the option shall vest on the last day of each month following the first anniversary of the vesting commencement date, subject to the Reporting Person continuing to be a service provider of the Issuer through each such date.

Read SEC document
January 11, 2019 Filed Jan 15, 2019 00:00 UTC
PATEL DINESH V PH DDirector · President and CEO
Exercise / conversionCommon Stock 22,344 $1.16 $25,919.04
Disclosure

SEC source: 0001209191-19-003606 · doc4.xml · nonDerivative · entry 1

PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 368,173

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
August 15, 2018 Filed Aug 18, 2018 00:25 UTC
PATEL DINESH V PH DDirector · President and CEO
GrantStock Option (right to buy) · Derivative 54,700 $0.00 Strike: $8.58 $0.00
Disclosure

SEC source: 0001209191-18-047547 · doc4.xml · derivative · entry 2

PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 54,700

Underlying: Common Stock · 54,700 shares

Expires 2028-08-14

F2 · derivative.exercise_date: 1/3rd of the total number of shares underlying this option shall vest on each of February 5, 2019, August 5, 2019 and February 5, 2020.

Read SEC document
August 15, 2018 Filed Aug 18, 2018 00:25 UTC
PATEL DINESH V PH DDirector · President and CEO
GrantCommon Stock 82,050 $0.00 $0.00
Disclosure

SEC source: 0001209191-18-047547 · doc4.xml · nonDerivative · entry 1

PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 345,829

F1 · shares: Represents grant of the restricted stock units payable solely in common stock that vest as follows: 1/3rd of the total number of shares shall vest on each of February 5, 2019, August 5, 2019 and February 5, 2020.

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August 15, 2018 Filed Aug 17, 2018 20:29 UTC
O'Neil Thomas P.Chief Financial Officer
GrantStock Option (right to buy) · Derivative 14,050 $0.00 Strike: $8.58 $0.00
Disclosure

SEC source: 0001209191-18-047549 · doc4.xml · derivative · entry 2

O'Neil Thomas P. · CIK 0001640645 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,050

Underlying: Common Stock · 14,050 shares

Expires 2028-08-14

F3 · derivative.exercise_date: 1/3rd of the total number of shares underlying this option shall vest on each of February 5, 2019, August 5, 2019 and February 5, 2020.

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August 15, 2018 Filed Aug 17, 2018 20:29 UTC
O'Neil Thomas P.Chief Financial Officer
GrantCommon Stock 21,100 $0.00 $0.00
Disclosure

SEC source: 0001209191-18-047549 · doc4.xml · nonDerivative · entry 1

O'Neil Thomas P. · CIK 0001640645 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,560

F1 · shares: Represents grant of the restricted stock units payable solely in common stock that vest as follows: 1/3rd of the total number of shares shall vest on each of February 5, 2019, August 5, 2019 and February 5, 2020.

F2 · balance_after: Includes 602 shares acquired by the Reporting Person under the Issuer's 2016 Employee Stock Purchase Plan on March 9, 2018.

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August 15, 2018 Filed Aug 18, 2018 00:28 UTC
Shames Richard S.Chief Medical Officer
GrantStock Option (right to buy) · Derivative 12,500 $0.00 Strike: $8.58 $0.00
Disclosure

SEC source: 0001209191-18-047548 · doc4.xml · derivative · entry 2

Shames Richard S. · CIK 0001675878 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,500

Underlying: Common Stock · 12,500 shares

Expires 2028-08-14

F3 · derivative.exercise_date: 1/3rd of the total number of shares underlying this option shall vest on each of February 5, 2019, August 5, 2019 and February 5, 2020.

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August 15, 2018 Filed Aug 18, 2018 00:28 UTC
Shames Richard S.Chief Medical Officer
GrantCommon Stock 18,750 $0.00 $0.00
Disclosure

SEC source: 0001209191-18-047548 · doc4.xml · nonDerivative · entry 1

Shames Richard S. · CIK 0001675878 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,956

F1 · shares: Represents grant of the restricted stock units payable solely in common stock that vest as follows: 1/3rd of the total number of shares shall vest on each of February 5, 2019, August 5, 2019 and February 5, 2020.

F2 · balance_after: Includes 1,706 shares acquired by the Reporting Person under the Issuer's 2016 Employee Stock Purchase Plan on March 9, 2018.

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August 15, 2018 Filed Aug 18, 2018 00:22 UTC
Liu David YChief Scientific Officer
GrantStock Option (right to buy) · Derivative 17,200 $0.00 Strike: $8.58 $0.00
Disclosure

SEC source: 0001209191-18-047543 · doc4.xml · derivative · entry 2

Liu David Y · CIK 0001675881 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,200

Underlying: Common Stock · 17,200 shares

Expires 2028-08-14

F2 · derivative.exercise_date: 1/3rd of the total number of shares underlying this option shall vest on each of February 5, 2019, August 5, 2019 and February 5, 2020.

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August 15, 2018 Filed Aug 18, 2018 00:22 UTC
Liu David YChief Scientific Officer
GrantCommon Stock 25,800 $0.00 $0.00
Disclosure

SEC source: 0001209191-18-047543 · doc4.xml · nonDerivative · entry 1

Liu David Y · CIK 0001675881 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,828

F1 · shares: Represents grant of the restricted stock units payable solely in common stock that vest as follows: 1/3rd of the total number of shares shall vest on each of February 5, 2019, August 5, 2019 and February 5, 2020.

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July 12, 2018 Filed Jul 13, 2018 22:36 UTC
PATEL DINESH V PH DDirector · President and CEO
GiftCommon Stock 2,000 $0.00 $0.00
Disclosure

SEC source: 0001209191-18-042575 · doc4.xml · nonDerivative · entry 1

PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 263,779

F1 · kind: This transaction involved a gift of securities by the Reporting Person to his son.

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May 31, 2018 Filed May 31, 2018 22:29 UTC
Saks Samuel RChief Development Officer
GrantStock Option (right to buy) · Derivative 50,000 $0.00 Strike: $7.28 $0.00
Disclosure

SEC source: 0001209191-18-034472 · doc4.xml · derivative · entry 1

Saks Samuel R · CIK 0001365615 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 50,000

Underlying: Common Stock · 50,000 shares

Expires 2028-05-30

F1 · derivative.exercise_date: The option vests over a four-year period, with 1/4th of the shares subject to the option vesting on the one year anniversary of the vesting commencement date of May 21, 2018, and 1/36th of the remaining shares subject to the option vesting each month.

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May 29, 2018 Filed Jun 12, 2018 18:40 UTC GrantStock Option (right to buy) · Derivative 12,000 $0.00 Strike: $6.98 $0.00
Disclosure

SEC source: 0001209191-18-037310 · doc4.xml · derivative · entry 1

KHOSLA CHAITAN PHD · CIK 0001135139 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,000

Underlying: Common Stock · 12,000 shares

Expires 2028-05-28

F1 · derivative.exercise_date: The shares subject to this option shall vest at the earlier on (i) May 29, 2019, or (ii) the date of the 2019 Annual Meeting of stockholders of the Issuer, subject to the non-employee director's continuous service with the Issuer through such dates. The shares subject to this option will vest in full upon completion of a Change in Control (as defined in the Issuer's 2016 Equity Incentive Plan).

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May 29, 2018 Filed Jun 12, 2018 18:43 UTC GrantStock Option (right to buy) · Derivative 12,000 $0.00 Strike: $6.98 $0.00
Disclosure

SEC source: 0001209191-18-037312 · doc4.xml · derivative · entry 1

Noonberg Sarah B. · CIK 0001706301 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,000

Underlying: Common Stock · 12,000 shares

Expires 2028-05-28

F1 · derivative.exercise_date: The shares subject to this option shall vest at the earlier on (i) May 29, 2019, or (ii) the date of the 2019 Annual Meeting of stockholders of the Issuer, subject to the non-employee director's continuous service with the Issuer through such dates. The shares subject to this option will vest in full upon completion of a Change in Control (as defined in the Issuer's 2016 Equity Incentive Plan).

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May 29, 2018 Filed Jun 12, 2018 18:50 UTC
Shanafelt ArmenDirector · 10% owner
GrantStock Option (right to buy) · Derivative 12,000 $0.00 Strike: $6.98 $0.00
Disclosure

SEC source: 0001209191-18-037316 · doc4.xml · derivative · entry 1

Shanafelt Armen · CIK 0001656151 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,000

Underlying: Common Stock · 12,000 shares

Expires 2028-05-28

F1 · derivative.exercise_date: The shares subject to this option shall vest at the earlier on (i) May 29, 2019, or (ii) the date of the 2019 Annual Meeting of stockholders of the Issuer, subject to the non-employee director's continuous service with the Issuer through such dates. The shares subject to this option will vest in full upon completion of a Change in Control (as defined in the Issuer's 2016 Equity Incentive Plan).

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May 29, 2018 Filed Jun 12, 2018 22:55 UTC GrantStock Option (right to buy) · Derivative 12,000 $0.00 Strike: $6.98 $0.00
Disclosure

SEC source: 0001209191-18-037318 · doc4.xml · derivative · entry 1

Williams Lewis T · CIK 0001475714 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,000

Underlying: Common Stock · 12,000 shares

Expires 2028-05-28

F1 · derivative.exercise_date: The shares subject to this option shall vest at the earlier on (i) May 29, 2019, or (ii) the date of the 2019 Annual Meeting of stockholders of the Issuer, subject to the non-employee director's continuous service with the Issuer through such dates. The shares subject to this option will vest in full upon completion of a Change in Control (as defined in the Issuer's 2016 Equity Incentive Plan).

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May 29, 2018 Filed Jun 12, 2018 22:52 UTC GrantStock Option (right to buy) · Derivative 12,000 $0.00 Strike: $6.98 $0.00
Disclosure

SEC source: 0001209191-18-037317 · doc4.xml · derivative · entry 1

Waddill William D. · CIK 0001553338 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,000

Underlying: Common Stock · 12,000 shares

Expires 2028-05-28

F1 · derivative.exercise_date: The shares subject to this option shall vest at the earlier on (i) May 29, 2019, or (ii) the date of the 2019 Annual Meeting of stockholders of the Issuer, subject to the non-employee director's continuous service with the Issuer through such dates. The shares subject to this option will vest in full upon completion of a Change in Control (as defined in the Issuer's 2016 Equity Incentive Plan).

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.