Last 12 months
Inside the activity.
0 purchase rows · 37 sale rows
Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.Monthly counts
| Month | Purchases | Sales |
|---|---|---|
| Nov 2025 | 0 | 1 |
| Dec 2025 | 0 | 0 |
| Jan 2026 | 0 | 12 |
| Feb 2026 | 0 | 2 |
| Mar 2026 | 0 | 5 |
| Apr 2026 | 0 | 1 |
| May 2026 | 0 | 7 |
| Jun 2026 | 0 | 2 |
| Jul 2026 | 0 | 0 |
| Aug 2026 | 0 | 2 |
| Sep 2026 | 0 | 5 |
| Oct 2026 | 0 | 0 |
Latest available
Insider transactions
Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”
The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.
| Transaction date | Owner / reported role | Activity / security | Shares / units | Reported price | Reported value | Details |
|---|---|---|---|---|---|---|
| November 16, 2022 Filed Nov 17, 2022 23:24 UTC |
Liu David YChief R&D Strategy Officer
|
Exercise / conversionStock Option (right to buy) · Derivative | 13,767 | $0.00 Strike: $0.87 | $0.00 |
DisclosureSEC source: 0001104659-22-119974 · tm2230775-3_4seq1.xml · derivative · entry 6 Liu David Y · CIK 0001675881 · Chief R&D Strategy Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 Underlying: Common Stock · 13,767 shares Expires 2023-09-26 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F2 · derivative.exercise_date: The stock option is vested in full. Read SEC document |
| November 16, 2022 Filed Nov 17, 2022 23:24 UTC |
Liu David YChief R&D Strategy Officer
|
Exercise / conversionCommon Stock | 35,331 | $4.21 | $148,743.51 |
DisclosureSEC source: 0001104659-22-119974 · tm2230775-3_4seq1.xml · nonDerivative · entry 5 Liu David Y · CIK 0001675881 · Chief R&D Strategy Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 167,590 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| November 16, 2022 Filed Nov 17, 2022 23:24 UTC |
Liu David YChief R&D Strategy Officer
|
Exercise / conversionCommon Stock | 35,656 | $1.16 | $41,360.96 |
DisclosureSEC source: 0001104659-22-119974 · tm2230775-3_4seq1.xml · nonDerivative · entry 4 Liu David Y · CIK 0001675881 · Chief R&D Strategy Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 132,259 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| November 16, 2022 Filed Nov 17, 2022 23:24 UTC |
Liu David YChief R&D Strategy Officer
|
Exercise / conversionCommon Stock | 5,999 | $1.89 | $11,338.11 |
DisclosureSEC source: 0001104659-22-119974 · tm2230775-3_4seq1.xml · nonDerivative · entry 3 Liu David Y · CIK 0001675881 · Chief R&D Strategy Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 96,603 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| November 16, 2022 Filed Nov 17, 2022 23:24 UTC |
Liu David YChief R&D Strategy Officer
|
Exercise / conversionCommon Stock | 9,726 | $1.89 | $18,382.14 |
DisclosureSEC source: 0001104659-22-119974 · tm2230775-3_4seq1.xml · nonDerivative · entry 2 Liu David Y · CIK 0001675881 · Chief R&D Strategy Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 90,604 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| November 16, 2022 Filed Nov 17, 2022 23:24 UTC |
Liu David YChief R&D Strategy Officer
|
Exercise / conversionCommon Stock | 13,767 | $0.87 | $11,977.29 |
DisclosureSEC source: 0001104659-22-119974 · tm2230775-3_4seq1.xml · nonDerivative · entry 1 Liu David Y · CIK 0001675881 · Chief R&D Strategy Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 80,878 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · balance_after: Includes an aggregate of 573 shares acquired by the Reporting Person under the Issuer's 2016 Employee Stock Purchase Plan on March 9, 2022 and September 9, 2022. Read SEC document |
| November 15, 2022 Filed Nov 17, 2022 23:22 UTC |
MOLINA ARTURO MDChief Medical Officer
|
GrantStock Option (right to buy) · Derivative | 127,500 | $0.00 Strike: $8.04 | $0.00 |
DisclosureSEC source: 0001104659-22-119971 · tm2230775-2_4seq1.xml · derivative · entry 2 MOLINA ARTURO MD · CIK 0001398940 · Chief Medical Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 127,500 Underlying: Common Stock · 127,500 shares Expires 2032-11-15 F2 · derivative.exercise_date: The stock option represents a right to purchase a total of 127,500 shares of the Issuer's common stock, one quarter of which will vest on November 7, 2023, with the remaining three quarters vesting in equal monthly installments through November 7, 2026, subject to the Reporting Person's continued service to the Issuer. Read SEC document |
| November 15, 2022 Filed Nov 17, 2022 23:22 UTC |
MOLINA ARTURO MDChief Medical Officer
|
GrantCommon Stock | 21,250 | $0.00 | $0.00 |
DisclosureSEC source: 0001104659-22-119971 · tm2230775-2_4seq1.xml · nonDerivative · entry 1 MOLINA ARTURO MD · CIK 0001398940 · Chief Medical Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 21,250 F1 · shares: Represents grant of restricted stock units payable solely in shares of the Issuer's common stock that will vest in four annual installments on November 15, 2023, 2024, 2025 and 2026, subject to the Reporting Person's continued service to the Issuer. Read SEC document |
| August 23, 2022 Filed Aug 24, 2022 22:15 UTC |
PATEL DINESH V PH DDirector · President and CEO
|
Exercise / conversionStock Option (right to buy) · Derivative | 20,000 | $0.00 Strike: $4.21 | $0.00 |
DisclosureSEC source: 0000899243-22-029621 · doc4.xml · derivative · entry 2 PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 60,000 Underlying: Common Stock · 20,000 shares Expires 2026-04-29 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · derivative.exercise_date: The stock option is vested in full. Read SEC document |
| August 23, 2022 Filed Aug 24, 2022 22:15 UTC |
PATEL DINESH V PH DDirector · President and CEO
|
Exercise / conversionCommon Stock | 20,000 | $4.21 | $84,200.00 |
DisclosureSEC source: 0000899243-22-029621 · doc4.xml · nonDerivative · entry 1 PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 604,048 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| May 26, 2022 Filed May 27, 2022 16:01 UTC |
Noonberg Sarah B.Director
|
GrantStock Option (right to buy) · Derivative | 20,000 | $0.00 Strike: $8.31 | $0.00 |
DisclosureSEC source: 0001104659-22-065863 · tm2214526-6_4seq1.xml · derivative · entry 1 Noonberg Sarah B. · CIK 0001706301 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 20,000 Underlying: Common Stock · 20,000 shares Expires 2032-05-26 F1 · derivative.exercise_date: The stock option vests in full on the earlier of (i) May 26, 2023 or (ii) the date of the Issuer's 2023 Annual Meeting of Stockholders, subject to the Reporting Person's continued service with the Issuer through such date. Read SEC document |
| May 26, 2022 Filed May 27, 2022 16:02 UTC |
O'Dowd Sarah ADirector
|
GrantStock Option (right to buy) · Derivative | 20,000 | $0.00 Strike: $8.31 | $0.00 |
DisclosureSEC source: 0001104659-22-065866 · tm2214526-7_4seq1.xml · derivative · entry 1 O'Dowd Sarah A · CIK 0001447149 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 20,000 Underlying: Common Stock · 20,000 shares Expires 2032-05-26 F1 · derivative.exercise_date: The stock option vests in full on the earlier of (i) May 26, 2023 or (ii) the date of the Issuer's 2023 Annual Meeting of Stockholders, subject to the Reporting Person's continued service with the Issuer through such date. Read SEC document |
| May 26, 2022 Filed May 27, 2022 20:02 UTC |
Waddill William D.Director
|
GrantStock Option (right to buy) · Derivative | 20,000 | $0.00 Strike: $8.31 | $0.00 |
DisclosureSEC source: 0001104659-22-065869 · tm2214526-8_4seq1.xml · derivative · entry 1 Waddill William D. · CIK 0001553338 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 20,000 Underlying: Common Stock · 20,000 shares Expires 2032-05-26 F1 · derivative.exercise_date: The stock option vests in full on the earlier of (i) May 26, 2023 or (ii) the date of the Issuer's 2023 Annual Meeting of Stockholders, subject to the Reporting Person's continued service with the Issuer through such date. Read SEC document |
| May 26, 2022 Filed May 27, 2022 20:00 UTC |
Giraudo BryanDirector
|
GrantStock Option (right to buy) · Derivative | 20,000 | $0.00 Strike: $8.31 | $0.00 |
DisclosureSEC source: 0001104659-22-065859 · tm2214526-3_4seq1.xml · derivative · entry 1 Giraudo Bryan · CIK 0001740847 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 20,000 Underlying: Common Stock · 20,000 shares Expires 2032-05-26 F1 · derivative.exercise_date: The stock option vests in full on the earlier of (i) May 26, 2023 or (ii) the date of the Issuer's 2023 Annual Meeting of Stockholders, subject to the Reporting Person's continued service with the Issuer through such date. Read SEC document |
| May 26, 2022 Filed May 27, 2022 20:01 UTC |
Williams Lewis TDirector
|
GrantStock Option (right to buy) · Derivative | 20,000 | $0.00 Strike: $8.31 | $0.00 |
DisclosureSEC source: 0001104659-22-065862 · tm2214526-5_4seq1.xml · derivative · entry 1 Williams Lewis T · CIK 0001475714 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 20,000 Underlying: Common Stock · 20,000 shares Expires 2032-05-26 F1 · derivative.exercise_date: The stock option vests in full on the earlier of (i) May 26, 2023 or (ii) the date of the Issuer's 2023 Annual Meeting of Stockholders, subject to the Reporting Person's continued service with the Issuer through such date. Read SEC document |
| May 26, 2022 Filed May 27, 2022 20:00 UTC |
SELICK HAROLD EDirector
|
GrantStock Option (right to buy) · Derivative | 20,000 | $0.00 Strike: $8.31 | $0.00 |
DisclosureSEC source: 0001104659-22-065860 · tm2214526-4_4seq1.xml · derivative · entry 1 SELICK HAROLD E · CIK 0001287233 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 20,000 Underlying: Common Stock · 20,000 shares Expires 2032-05-26 F1 · derivative.exercise_date: The stock option vests in full on the earlier of (i) May 26, 2023 or (ii) the date of the Issuer's 2023 Annual Meeting of Stockholders, subject to the Reporting Person's continued service with the Issuer through such date. Read SEC document |
| May 04, 2022 Filed May 5, 2022 00:33 UTC |
PATEL DINESH V PH DDirector · President and CEO
|
Exercise / conversionStock Option (right to buy) · Derivative | 15,742 | $0.00 Strike: $4.21 | $0.00 |
DisclosureSEC source: 0001104659-22-055995 · tm2214526-2_4seq1.xml · derivative · entry 2 PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 80,000 Underlying: Common Stock · 15,742 shares Expires 2026-04-29 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · derivative.exercise_date: The stock option is vested in full. Read SEC document |
| May 04, 2022 Filed May 5, 2022 00:33 UTC |
PATEL DINESH V PH DDirector · President and CEO
|
Exercise / conversionCommon Stock | 15,742 | $4.21 | $66,273.82 |
DisclosureSEC source: 0001104659-22-055995 · tm2214526-2_4seq1.xml · nonDerivative · entry 1 PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 584,048 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| May 04, 2022 Filed Jan 19, 2023 00:48 UTC |
PATEL DINESH V PH DDirector · President and CEO
|
GiftCommon Stock | 3,000 | $0.00 | $0.00 |
DisclosureSEC source: 0001104659-23-004721 · tm233829-7_4.xml · nonDerivative · entry 1 PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 581,048 Read SEC document |
| May 03, 2022 Filed May 5, 2022 00:41 UTC |
Waddill William D.Director
|
Exercise / conversionStock Option (right to buy) · Derivative | 12,000 | $0.00 Strike: $8.59 | $0.00 |
DisclosureSEC source: 0001104659-22-056000 · tm2214526-1_4seq1.xml · derivative · entry 2 Waddill William D. · CIK 0001553338 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 Underlying: Common Stock · 12,000 shares Expires 2027-05-25 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · derivative.exercise_date: The shares subject to this option are vested in full. Read SEC document |
| May 03, 2022 Filed May 5, 2022 00:41 UTC |
Waddill William D.Director
|
Exercise / conversionCommon Stock | 12,000 | $8.59 | $103,080.00 |
DisclosureSEC source: 0001104659-22-056000 · tm2214526-1_4seq1.xml · nonDerivative · entry 1 Waddill William D. · CIK 0001553338 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 12,000 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| April 26, 2022 Filed Apr 27, 2022 01:34 UTC |
PATEL DINESH V PH DDirector · President and CEO
|
Exercise / conversionStock Option (right to buy) · Derivative | 30,000 | $0.00 Strike: $4.21 | $0.00 |
DisclosureSEC source: 0001104659-22-050551 · tm2212815-4_4seq1.xml · derivative · entry 2 PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 95,742 Underlying: Common Stock · 30,000 shares Expires 2026-04-29 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F2 · derivative.exercise_date: The stock option is vested in full. Read SEC document |
| April 26, 2022 Filed Apr 27, 2022 01:34 UTC |
PATEL DINESH V PH DDirector · President and CEO
|
Exercise / conversionCommon Stock | 30,000 | $4.21 | $126,300.00 |
DisclosureSEC source: 0001104659-22-050551 · tm2212815-4_4seq1.xml · nonDerivative · entry 1 PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 568,306 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · balance_after: Includes an aggregate of 459 shares acquired by the Reporting Person under the Issuer's 2016 Employee Stock Purchase Plan on March 9, 2022. Read SEC document |
| April 26, 2022 Filed Apr 27, 2022 01:42 UTC |
Gupta SuneelChief Development Officer
|
Exercise / conversionStock Option (right to buy) · Derivative | 40,000 | $0.00 Strike: $7.38 | $0.00 |
DisclosureSEC source: 0001104659-22-050560 · tm2212815-5_4seq1.xml · derivative · entry 2 Gupta Suneel · CIK 0001763923 · Chief Development Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 70,000 Underlying: Common Stock · 40,000 shares Expires 2029-01-14 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F2 · derivative.exercise_date: The stock option vests over a four-year period, with 1/4th of the shares subject to the option vesting on January 15, 2020, and 1/36th of the remaining shares subject to the option vesting each month, subject to the Reporting Person continuing to be a service provider of the Issuer through each such date. Read SEC document |
| April 26, 2022 Filed Apr 27, 2022 01:42 UTC |
Gupta SuneelChief Development Officer
|
Exercise / conversionCommon Stock | 40,000 | $7.38 | $295,200.00 |
DisclosureSEC source: 0001104659-22-050560 · tm2212815-5_4seq1.xml · nonDerivative · entry 1 Gupta Suneel · CIK 0001763923 · Chief Development Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 117,561 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · balance_after: Includes an aggregate of 554 shares acquired by the Reporting Person under the Issuer's 2016 Employee Stock Purchase Plan on March 9, 2022. Read SEC document |
| April 18, 2022 Filed Apr 19, 2022 23:48 UTC |
Ali AsifChief Financial Officer
|
GrantStock Option (right to buy) · Derivative | 82,500 | $0.00 Strike: $19.19 | $0.00 |
DisclosureSEC source: 0001104659-22-047468 · tm2212815-3_4seq1.xml · derivative · entry 2 Ali Asif · CIK 0001921163 · Chief Financial Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 82,500 Underlying: Common Stock · 82,500 shares Expires 2032-04-18 F2 · derivative.exercise_date: The stock option represents a right to purchase a total of 82,500 shares of the Issuer's common stock, one quarter of which will vest on April 18, 2023, with the remaining three quarters vesting in equal monthly installments through April 18, 2026, subject to the Reporting Person's continued service to the Issuer. Read SEC document |
| April 18, 2022 Filed Apr 19, 2022 23:48 UTC |
Ali AsifChief Financial Officer
|
GrantCommon Stock | 13,750 | $0.00 | $0.00 |
DisclosureSEC source: 0001104659-22-047468 · tm2212815-3_4seq1.xml · nonDerivative · entry 1 Ali Asif · CIK 0001921163 · Chief Financial Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 13,750 F1 · shares: Represents grant of restricted stock units payable solely in shares of the Issuer's common stock that will vest in four annual installments on April 18, 2023, 2024, 2025 and 2026, subject to the Reporting Person's continued service to the Issuer. Read SEC document |
| April 14, 2022 Filed Apr 15, 2022 00:09 UTC |
PATEL DINESH V PH DDirector · President and CEO · 10% owner
|
Exercise / conversionStock Option (right to buy) · Derivative | 34,087 | $0.00 Strike: $1.89 | $0.00 |
DisclosureSEC source: 0001104659-22-046158 · tm2212815-1_4seq1.xml · derivative · entry 2 PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO · 10% owner 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 Underlying: Common Stock · 34,087 shares Expires 2024-10-22 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · derivative.exercise_date: The stock option is vested in full. Read SEC document |
| April 14, 2022 Filed Apr 15, 2022 00:09 UTC |
PATEL DINESH V PH DDirector · President and CEO · 10% owner
|
Exercise / conversionCommon Stock | 34,087 | $1.89 | $64,424.43 |
DisclosureSEC source: 0001104659-22-046158 · tm2212815-1_4seq1.xml · nonDerivative · entry 1 PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO · 10% owner 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 537,847 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| February 28, 2022 Filed Mar 3, 2022 01:39 UTC |
PATEL DINESH V PH DDirector · President and CEO
|
Tax withholdingCommon Stock | 4,648 | $24.28 | $112,853.44 |
DisclosureSEC source: 0001104659-22-029520 · tm228264-2_4seq1.xml · nonDerivative · entry 1 PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 503,760 F1 · shares: Represents shares withheld by the Issuer to satisfy tax withholding obligations in connection with the release of 13,438 vested restricted stock units on February 28, 2022. Read SEC document |
| February 28, 2022 Filed Mar 3, 2022 01:40 UTC |
Gupta SuneelChief Development Officer
|
Tax withholdingCommon Stock | 649 | $24.28 | $15,757.72 |
DisclosureSEC source: 0001104659-22-029522 · tm228264-3_4seq1.xml · nonDerivative · entry 1 Gupta Suneel · CIK 0001763923 · Chief Development Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 77,007 F1 · shares: Represents shares withheld by the Issuer to satisfy tax withholding obligations in connection with the release of 1,875 vested restricted stock units on February 28, 2022. Read SEC document |
| February 28, 2022 Filed Mar 3, 2022 01:38 UTC |
Liu David YChief Scientific Officer
|
Tax withholdingCommon Stock | 2,119 | $24.28 | $51,449.32 |
DisclosureSEC source: 0001104659-22-029519 · tm228264-1_4seq1.xml · nonDerivative · entry 1 Liu David Y · CIK 0001675881 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 66,538 F1 · shares: Represents shares withheld by the Issuer to satisfy tax withholding obligations in connection with the release of 6,125 vested restricted stock units on February 28, 2022. Read SEC document |
| February 15, 2022 Filed Feb 18, 2022 00:23 UTC |
PATEL DINESH V PH DDirector · President and CEO
|
GrantStock Option (right to buy) · Derivative | 187,500 | $0.00 Strike: $28.73 | $0.00 |
DisclosureSEC source: 0001104659-22-024835 · tm227111-1_4seq1.xml · derivative · entry 2 PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 187,500 Underlying: Common Stock · 187,500 shares Expires 2032-02-14 F2 · derivative.exercise_date: The stock option vests in 48 equal monthly installments following the date of grant. Read SEC document |
| February 15, 2022 Filed Feb 18, 2022 00:23 UTC |
PATEL DINESH V PH DDirector · President and CEO
|
GrantCommon Stock | 31,250 | $0.00 | $0.00 |
DisclosureSEC source: 0001104659-22-024835 · tm227111-1_4seq1.xml · nonDerivative · entry 1 PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 508,408 F1 · shares: Represents grant of restricted stock units payable solely in common stock that will vest in three annual installments on February 15, 2023, 2024 and 2025. Read SEC document |
| February 15, 2022 Filed Feb 18, 2022 00:26 UTC |
Kalkofen Donald A.Chief Financial Officer
|
GrantStock Option (right to buy) · Derivative | 45,000 | $0.00 Strike: $28.73 | $0.00 |
DisclosureSEC source: 0001104659-22-024841 · tm227111-4_4seq1.xml · derivative · entry 2 Kalkofen Donald A. · CIK 0001771066 · Chief Financial Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 45,000 Underlying: Common Stock · 45,000 shares Expires 2032-02-14 F3 · derivative.exercise_date: The stock option vests in 48 equal monthly installments following the date of grant. Read SEC document |
| February 15, 2022 Filed Feb 18, 2022 00:26 UTC |
Kalkofen Donald A.Chief Financial Officer
|
GrantCommon Stock | 7,500 | $0.00 | $0.00 |
DisclosureSEC source: 0001104659-22-024841 · tm227111-4_4seq1.xml · nonDerivative · entry 1 Kalkofen Donald A. · CIK 0001771066 · Chief Financial Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 18,521 F1 · shares: Represents grant of restricted stock units payable solely in common stock that will vest in three annual installments on February 15, 2023, 2024 and 2025. F2 · balance_after: Includes an aggregate of 635 shares acquired by the Reporting Person under the Issuer's 2016 Employee Stock Purchase Plan on March 9, 2021. Read SEC document |
| February 15, 2022 Filed Feb 18, 2022 00:25 UTC |
Liu David YChief Scientific Officer
|
GrantStock Option (right to buy) · Derivative | 60,000 | $0.00 Strike: $28.73 | $0.00 |
DisclosureSEC source: 0001104659-22-024840 · tm227111-3_4seq1.xml · derivative · entry 2 Liu David Y · CIK 0001675881 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 60,000 Underlying: Common Stock · 60,000 shares Expires 2032-02-14 F3 · derivative.exercise_date: The stock option vests in 48 equal monthly installments following the date of grant. Read SEC document |
| February 15, 2022 Filed Feb 18, 2022 00:25 UTC |
Liu David YChief Scientific Officer
|
GrantCommon Stock | 10,000 | $0.00 | $0.00 |
DisclosureSEC source: 0001104659-22-024840 · tm227111-3_4seq1.xml · nonDerivative · entry 1 Liu David Y · CIK 0001675881 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 68,657 F1 · shares: Represents grant of restricted stock units payable solely in common stock that will vest in three annual installments on February 15, 2023, 2024 and 2025. F2 · balance_after: Includes an aggregate of 403 shares acquired by the Reporting Person under the Issuer's 2016 Employee Stock Purchase Plan on September 9, 2021. Read SEC document |
| February 15, 2022 Filed Feb 18, 2022 00:24 UTC |
Gupta SuneelChief Development Officer
|
GrantStock Option (right to buy) · Derivative | 75,000 | $0.00 Strike: $28.73 | $0.00 |
DisclosureSEC source: 0001104659-22-024838 · tm227111-2_4seq1.xml · derivative · entry 2 Gupta Suneel · CIK 0001763923 · Chief Development Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 75,000 Underlying: Common Stock · 75,000 shares Expires 2032-02-14 F3 · derivative.exercise_date: The stock option vests in 48 equal monthly installments following the date of grant. Read SEC document |
| February 15, 2022 Filed Feb 18, 2022 00:24 UTC |
Gupta SuneelChief Development Officer
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GrantCommon Stock | 12,500 | $0.00 | $0.00 |
DisclosureSEC source: 0001104659-22-024838 · tm227111-2_4seq1.xml · nonDerivative · entry 1 Gupta Suneel · CIK 0001763923 · Chief Development Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 77,656 F1 · shares: Represents grant of restricted stock units payable solely in common stock that will vest in three annual installments on February 15, 2023, 2024 and 2025. F2 · balance_after: Includes an aggregate of 1,169 shares acquired by the Reporting Person under the Issuer's 2016 Employee Stock Purchase Plan on March 9, 2021. Read SEC document |
| December 21, 2021 Filed Dec 23, 2021 21:17 UTC |
PATEL DINESH V PH DDirector · President and CEO
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SaleCommon Stock | 15,000 | $32.14 | $482,170.50 |
DisclosureSEC source: 0001104659-21-153135 · tm2136222-1_4seq1.xml · nonDerivative · entry 1 PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 477,158 F1 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $31.86 to $32.41, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range. Read SEC document |
| September 21, 2021 Filed Sep 22, 2021 01:45 UTC |
PATEL DINESH V PH DDirector · President and CEO
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Exercise / conversionStock Option (right to buy) · Derivative | 40,000 | $0.00 Strike: $4.21 | $0.00 |
DisclosureSEC source: 0001104659-21-118054 · tm2128192-1_4seq1.xml · derivative · entry 2 PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 125,742 Underlying: Common Stock · 40,000 shares Expires 2026-04-29 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F2 · derivative.exercise_date: The stock option is vested in full. Read SEC document |
| September 21, 2021 Filed Sep 22, 2021 01:45 UTC |
PATEL DINESH V PH DDirector · President and CEO
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Exercise / conversionCommon Stock | 40,000 | $4.21 | $168,400.00 |
DisclosureSEC source: 0001104659-21-118054 · tm2128192-1_4seq1.xml · nonDerivative · entry 1 PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 492,158 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · balance_after: Includes an aggregate of 1,014 shares acquired by the Reporting Person under the Issuer's 2016 Employee Stock Purchase Plan on March 9, 2021 and September 9, 2021. Read SEC document |
| August 17, 2021 Filed Aug 19, 2021 21:49 UTC |
Liu David YChief Scientific Officer
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Exercise / conversionStock Option (right to buy) · Derivative | 10,000 | $0.00 Strike: $0.87 | $0.00 |
DisclosureSEC source: 0001104659-21-107818 · tm2125489-1_4seq1.xml · derivative · entry 3 Liu David Y · CIK 0001675881 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 13,767 Underlying: Common Stock · 10,000 shares Expires 2023-09-26 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F4 · derivative.exercise_date: The stock option is vested in full. Read SEC document |
| August 17, 2021 Filed Aug 19, 2021 21:49 UTC |
Liu David YChief Scientific Officer
|
SaleCommon Stock | 14,779 | $47.56 | $702,889.24 |
DisclosureSEC source: 0001104659-21-107818 · tm2125489-1_4seq1.xml · nonDerivative · entry 2 Liu David Y · CIK 0001675881 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 58,254 F2 · shares: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on July 7, 2021. F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $47.10 to $48.34. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range. F1 · balance_after: Includes an aggregate of 606 shares acquired by the Reporting Person under the Issuer's 2016 Employee Stock Purchase Plan on March 9, 2021. Read SEC document |
| August 17, 2021 Filed Aug 19, 2021 21:49 UTC |
Liu David YChief Scientific Officer
|
Exercise / conversionCommon Stock | 10,000 | $0.87 | $8,700.00 |
DisclosureSEC source: 0001104659-21-107818 · tm2125489-1_4seq1.xml · nonDerivative · entry 1 Liu David Y · CIK 0001675881 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 73,033 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · balance_after: Includes an aggregate of 606 shares acquired by the Reporting Person under the Issuer's 2016 Employee Stock Purchase Plan on March 9, 2021. Read SEC document |
| May 27, 2021 Filed May 28, 2021 18:43 UTC |
Noonberg Sarah B.Director
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GrantStock Option (right to buy) · Derivative | 18,000 | $0.00 Strike: $35.23 | $0.00 |
DisclosureSEC source: 0001209191-21-036663 · doc4.xml · derivative · entry 1 Noonberg Sarah B. · CIK 0001706301 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 18,000 Underlying: Common Stock · 18,000 shares Expires 2031-05-26 F1 · derivative.exercise_date: The shares subject to this option shall vest at the earlier of (i) May 27, 2022, or (ii) the date of the 2022 Annual Meeting of stockholders of the Issuer, subject to the non-employee director's continuous service with the Issuer through such dates. The shares subject to this option will vest in full upon completion of a Change in Control (as defined in the Issuer's 2016 Equity Incentive Plan). Read SEC document |
| May 27, 2021 Filed May 28, 2021 18:50 UTC |
O'Dowd Sarah ADirector
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GrantStock Option (right to buy) · Derivative | 18,000 | $0.00 Strike: $35.23 | $0.00 |
DisclosureSEC source: 0001209191-21-036664 · doc4.xml · derivative · entry 1 O'Dowd Sarah A · CIK 0001447149 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 18,000 Underlying: Common Stock · 18,000 shares Expires 2031-05-26 F1 · derivative.exercise_date: The shares subject to this option shall vest at the earlier of (i) May 27, 2022, or (ii) the date of the 2022 Annual Meeting of stockholders of the Issuer, subject to the non-employee director's continuous service with the Issuer through such dates. The shares subject to this option will vest in full upon completion of a Change in Control (as defined in the Issuer's 2016 Equity Incentive Plan). Read SEC document |
| May 27, 2021 Filed May 28, 2021 23:06 UTC |
Williams Lewis TDirector
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GrantStock Option (right to buy) · Derivative | 18,000 | $0.00 Strike: $35.23 | $0.00 |
DisclosureSEC source: 0001209191-21-036680 · doc4.xml · derivative · entry 1 Williams Lewis T · CIK 0001475714 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 18,000 Underlying: Common Stock · 18,000 shares Expires 2031-05-26 F1 · derivative.exercise_date: The shares subject to this option shall vest at the earlier of (i) May 27, 2022, or (ii) the date of the 2022 Annual Meeting of stockholders of the Issuer, subject to the non-employee director's continuous service with the Issuer through such dates. The shares subject to this option will vest in full upon completion of a Change in Control (as defined in the Issuer's 2016 Equity Incentive Plan). Read SEC document |
| May 27, 2021 Filed May 28, 2021 23:02 UTC |
Waddill William D.Director
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GrantStock Option (right to buy) · Derivative | 18,000 | $0.00 Strike: $35.23 | $0.00 |
DisclosureSEC source: 0001209191-21-036670 · doc4.xml · derivative · entry 1 Waddill William D. · CIK 0001553338 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 18,000 Underlying: Common Stock · 18,000 shares Expires 2031-05-26 F1 · derivative.exercise_date: The shares subject to this option shall vest at the earlier of (i) May 27, 2022, or (ii) the date of the 2022 Annual Meeting of stockholders of the Issuer, subject to the non-employee director's continuous service with the Issuer through such dates. The shares subject to this option will vest in full upon completion of a Change in Control (as defined in the Issuer's 2016 Equity Incentive Plan). Read SEC document |
Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.