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Nasdaq · USD

PTGX

Protagonist Therapeutics, Inc

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Tapewire entity
3552
SEC CIK
0001377121
Parsed reports
275

Last 12 months

Inside the activity.

0 purchase rows · 37 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202501
Dec 202500
Jan 2026012
Feb 202602
Mar 202605
Apr 202601
May 202607
Jun 202602
Jul 202600
Aug 202602
Sep 202605
Oct 202600

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
December 18, 2017 Filed Dec 20, 2017 21:08 UTC
O'Neil Thomas P.Chief Financial Officer
Exercise / conversionEmployee Stock Option (right to buy) · Derivative 4,000 $0.00 Strike: $1.16 $0.00
Disclosure

SEC source: 0001209191-17-066697 · doc4.xml · derivative · entry 4

O'Neil Thomas P. · CIK 0001640645 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 57,666

Underlying: Common Stock · 4,000 shares

Expires 2026-02-08

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests over a four-year period, with 1/4th of the shares subject to the option vesting on the one year anniversary of the vesting commencement date, and 1/36th of the remaining shares subject to the option vesting each month, subject to the Reporting Person continuing to be a service provider of the Issuer through each such date.

Read SEC document
December 18, 2017 Filed Dec 20, 2017 21:08 UTC
O'Neil Thomas P.Chief Financial Officer
Sale12/18/2017 8,000 $20.00 $160,000.00
Disclosure

SEC source: 0001209191-17-066697 · doc4.xml · nonDerivative · entry 3

O'Neil Thomas P. · CIK 0001640645 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on February 9, 2017.

Read SEC document
December 18, 2017 Filed Dec 20, 2017 21:08 UTC
O'Neil Thomas P.Chief Financial Officer
Exercise / conversionCommon Stock 4,000 $4.21 $16,840.00
Disclosure

SEC source: 0001209191-17-066697 · doc4.xml · nonDerivative · entry 2

O'Neil Thomas P. · CIK 0001640645 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
December 18, 2017 Filed Dec 20, 2017 21:08 UTC
O'Neil Thomas P.Chief Financial Officer
Exercise / conversionCommon Stock 4,000 $1.16 $4,640.00
Disclosure

SEC source: 0001209191-17-066697 · doc4.xml · nonDerivative · entry 1

O'Neil Thomas P. · CIK 0001640645 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
December 18, 2017 Filed Dec 21, 2017 02:13 UTC
Liu David YChief Scientific Officer
Exercise / conversionEmployee Stock Option (right to buy) · Derivative 875 $0.00 Strike: $1.89 $0.00
Disclosure

SEC source: 0001209191-17-066698 · doc4.xml · derivative · entry 3

Liu David Y · CIK 0001675881 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,475

Underlying: Common Stock · 875 shares

Expires 2024-10-22

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests over a four-year period, with 1/4th of the shares subject to the option vesting on the one year anniversary of the vesting commencement date, and 1/36th of the remaining shares subject to the option vesting each month, subject to the Reporting Person continuing to be a service provider of the Issuer through each such date.

Read SEC document
December 18, 2017 Filed Dec 21, 2017 02:13 UTC
Liu David YChief Scientific Officer
SaleCommon Stock 875 $20.00 $17,500.00
Disclosure

SEC source: 0001209191-17-066698 · doc4.xml · nonDerivative · entry 2

Liu David Y · CIK 0001675881 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,822

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on February 6, 2017.

Read SEC document
December 18, 2017 Filed Dec 21, 2017 02:13 UTC
Liu David YChief Scientific Officer
Exercise / conversionCommon Stock 875 $1.89 $1,653.75
Disclosure

SEC source: 0001209191-17-066698 · doc4.xml · nonDerivative · entry 1

Liu David Y · CIK 0001675881 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,697

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
December 15, 2017 Filed Dec 19, 2017 20:30 UTC GrantStock Option (right to buy) · Derivative 24,000 $0.00 Strike: $17.57 $0.00
Disclosure

SEC source: 0001209191-17-066553 · doc4.xml · derivative · entry 1

Noonberg Sarah B. · CIK 0001706301 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,000

Underlying: Common Stock · 24,000 shares

Expires 2027-12-14

F1 · derivative.exercise_date: The shares subject to the option shall vest in 36 equal monthly installments from the vesting commencement date of December 12, 2017.

Read SEC document
December 15, 2017 Filed Mar 15, 2018 19:26 UTC Amendment GrantStock Option (right to buy) · Derivative 24,000 $0.00 Strike: $18.99 $0.00
Disclosure

SEC source: 0001209191-18-019990 · doc4a.xml · derivative · entry 1

Noonberg Sarah B. · CIK 0001706301 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,000

Underlying: Common Stock · 24,000 shares

Expires 2027-12-14

F1 · derivative.exercise_price: This amendment to the previously filed Form 4 is being filed to correct a typographical error in the exercise price of the option to purchase common stock of the Issuer held by the Reporting Person.

F2 · derivative.exercise_date: The shares subject to the option shall vest in 36 equal monthly installments from the vesting commencement date of December 12, 2017.

Read SEC document
November 30, 2017 Filed Dec 1, 2017 23:56 UTC
Liu David YChief Scientific Officer
Exercise / conversionEmployee Stock Option (right to buy) · Derivative 875 $0.00 Strike: $1.89 $0.00
Disclosure

SEC source: 0001209191-17-063316 · doc4.xml · derivative · entry 3

Liu David Y · CIK 0001675881 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,350

Underlying: Common Stock · 875 shares

Expires 2024-10-22

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests over a four-year period, with 1/4th of the shares subject to the option vesting on the one year anniversary of the vesting commencement date, and 1/36th of the remaining shares subject to the option vesting each month, subject to the Reporting Person continuing to be a service provider of the Issuer through each such date.

Read SEC document
November 30, 2017 Filed Dec 1, 2017 23:56 UTC
Liu David YChief Scientific Officer
SaleCommon Stock 875 $20.00 $17,500.00
Disclosure

SEC source: 0001209191-17-063316 · doc4.xml · nonDerivative · entry 2

Liu David Y · CIK 0001675881 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,822

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on February 6, 2017.

Read SEC document
November 30, 2017 Filed Dec 1, 2017 23:56 UTC
Liu David YChief Scientific Officer
GrantCommon Stock 875 $1.89 $1,653.75
Disclosure

SEC source: 0001209191-17-063316 · doc4.xml · nonDerivative · entry 1

Liu David Y · CIK 0001675881 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,697

Read SEC document
November 13, 2017 Filed Nov 16, 2017 00:14 UTC
Liu David YChief Scientific Officer
Exercise / conversionEmployee Stock Option (right to buy) · Derivative 3,500 $0.00 Strike: $1.89 $0.00
Disclosure

SEC source: 0001209191-17-061002 · doc4.xml · derivative · entry 6

Liu David Y · CIK 0001675881 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,225

Underlying: Common Stock · 3,500 shares

Expires 2024-10-22

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: The option vests over a four-year period, with 1/4th of the shares subject to the option vesting on the one year anniversary of the vesting commencement date, and 1/36th of the remaining shares subject to the option vesting each month, subject to the Reporting Person continuing to be a service provider of the Issuer through each such date.

Read SEC document
November 13, 2017 Filed Nov 16, 2017 00:14 UTC
Liu David YChief Scientific Officer
Exercise / conversionEmployee Stock Option (right to buy) · Derivative 3,500 $0.00 Strike: $4.21 $0.00
Disclosure

SEC source: 0001209191-17-061002 · doc4.xml · derivative · entry 5

Liu David Y · CIK 0001675881 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,831

Underlying: Common Stock · 3,500 shares

Expires 2026-04-29

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: The option vests over a four-year period, with 1/48th of the shares subject to the option vesting on the last day of each month following the vesting commencement date, subject to the Reporting Person continuing to be a service provider of the Issuer through each such date.

Read SEC document
November 13, 2017 Filed Nov 16, 2017 00:14 UTC
Liu David YChief Scientific Officer
SaleCommon Stock 3,500 $16.97 $59,380.65
Disclosure

SEC source: 0001209191-17-061002 · doc4.xml · nonDerivative · entry 4

Liu David Y · CIK 0001675881 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,822

F2 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on February 6, 2017.

Read SEC document
November 13, 2017 Filed Nov 16, 2017 00:14 UTC
Liu David YChief Scientific Officer
Exercise / conversionCommon Stock 3,500 $1.89 $6,615.00
Disclosure

SEC source: 0001209191-17-061002 · doc4.xml · nonDerivative · entry 3

Liu David Y · CIK 0001675881 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,322

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 13, 2017 Filed Nov 16, 2017 00:14 UTC
Liu David YChief Scientific Officer
SaleCommon Stock 3,500 $16.97 $59,380.65
Disclosure

SEC source: 0001209191-17-061002 · doc4.xml · nonDerivative · entry 2

Liu David Y · CIK 0001675881 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,822

F2 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on February 6, 2017.

Read SEC document
November 13, 2017 Filed Nov 16, 2017 00:14 UTC
Liu David YChief Scientific Officer
Exercise / conversionCommon Stock 3,500 $4.21 $14,735.00
Disclosure

SEC source: 0001209191-17-061002 · doc4.xml · nonDerivative · entry 1

Liu David Y · CIK 0001675881 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,322

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · balance_after: Includes 1,822 shares acquired by the Reporting Person under the Issuer's 2016 Employee Stock Purchase Plan on September 8, 2017.

Read SEC document
October 05, 2017 Filed Oct 10, 2017 23:04 UTC
Shames Richard S.Chief Medical Officer
Exercise / conversionStock Option (right to buy) · Derivative 2,017 $0.00 Strike: $4.21 $0.00
Disclosure

SEC source: 0001209191-17-056551 · doc4.xml · derivative · entry 3

Shames Richard S. · CIK 0001675878 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,802

Underlying: Common Stock · 2,017 shares

Expires 2026-04-29

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests over a four-year period, with 1/4th of the shares subject to the option vesting on the one year anniversary of the vesting commencement date, and 1/36th of the remaining shares subject to the option vesting each month, subject to the Reporting Person continuing to be a service provider of the Issuer through each such date.

Read SEC document
October 05, 2017 Filed Oct 10, 2017 23:04 UTC
Shames Richard S.Chief Medical Officer
SaleCommon Stock 2,017 $19.00 $38,323.00
Disclosure

SEC source: 0001209191-17-056551 · doc4.xml · nonDerivative · entry 2

Shames Richard S. · CIK 0001675878 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on February 9, 2017.

Read SEC document
October 05, 2017 Filed Oct 10, 2017 23:04 UTC
Shames Richard S.Chief Medical Officer
Exercise / conversionCommon Stock 2,017 $4.21 $8,491.57
Disclosure

SEC source: 0001209191-17-056551 · doc4.xml · nonDerivative · entry 1

Shames Richard S. · CIK 0001675878 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,017

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
September 12, 2017 Filed Sep 12, 2017 23:50 UTC
Shames Richard S.Chief Medical Officer
SaleCommon Stock 3,687 $14.31 $52,752.86
Disclosure

SEC source: 0001209191-17-052501 · doc4.xml · nonDerivative · entry 1

Shames Richard S. · CIK 0001675878 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on February 9, 2017.

F2 · shares: Includes 1,822 shares acquired by the Reporting Person under the Issuer's 2016 Employee Stock Purchase Plan on September 8, 2017.

F3 · price: The shares were sold at prices ranging from $14.251 to $14.3443. The reporting person will provide upon request to the SEC, the issuer or security holder of the issuer, full information regarding the number of shares sold at each separate price.

Read SEC document
August 29, 2017 Filed Aug 30, 2017 23:08 UTC
Shames Richard S.Chief Medical Officer
Exercise / conversionStock Option (right to buy) · Derivative 1,512 $0.00 Strike: $4.21 $0.00
Disclosure

SEC source: 0001209191-17-050815 · doc4.xml · derivative · entry 3

Shames Richard S. · CIK 0001675878 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,819

Underlying: Common Stock · 1,512 shares

Expires 2026-04-29

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: The option vests over a four-year period, with 1/4th of the shares subject to the option vesting on the one year anniversary of the vesting commencement date, and 1/36th of the remaining shares subject to the option vesting each month, subject to the Reporting Person continuing to be a service provider of the Issuer through each such date.

Read SEC document
August 29, 2017 Filed Aug 30, 2017 23:08 UTC
Shames Richard S.Chief Medical Officer
SaleCommon Stock 1,512 $17.00 $25,704.00
Disclosure

SEC source: 0001209191-17-050815 · doc4.xml · nonDerivative · entry 2

Shames Richard S. · CIK 0001675878 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,865

F2 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on February 9, 2017.

Read SEC document
August 29, 2017 Filed Aug 30, 2017 23:08 UTC
Shames Richard S.Chief Medical Officer
Exercise / conversionCommon Stock 1,512 $4.21 $6,365.52
Disclosure

SEC source: 0001209191-17-050815 · doc4.xml · nonDerivative · entry 1

Shames Richard S. · CIK 0001675878 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,377

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · balance_after: Includes 1,865 shares acquired by the Reporting Person under the Issuer's 2016 Employee Stock Purchase Plan on March 9, 2017.

Read SEC document
August 28, 2017 Filed Aug 29, 2017 23:48 UTC
Liu David YChief Scientific Officer
Exercise / conversionEmployee Stock Option (right to buy) · Derivative 3,500 $0.00 Strike: $4.21 $0.00
Disclosure

SEC source: 0001209191-17-050652 · doc4.xml · derivative · entry 3

Liu David Y · CIK 0001675881 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 42,331

Underlying: Common Stock · 3,500 shares

Expires 2026-04-29

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests over a four-year period, with 1/48th of the shares subject to the option vesting on the last day of each month following the vesting commencement date, subject to the Reporting Person continuing to be a service provider of the Issuer through each such date.

Read SEC document
August 28, 2017 Filed Aug 29, 2017 23:48 UTC
Liu David YChief Scientific Officer
SaleCommon Stock 3,500 $15.00 $52,500.00
Disclosure

SEC source: 0001209191-17-050652 · doc4.xml · nonDerivative · entry 2

Liu David Y · CIK 0001675881 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,000

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on February 6, 2017.

Read SEC document
August 28, 2017 Filed Aug 29, 2017 23:48 UTC
Liu David YChief Scientific Officer
Exercise / conversionCommon Stock 3,500 $4.21 $14,735.00
Disclosure

SEC source: 0001209191-17-050652 · doc4.xml · nonDerivative · entry 1

Liu David Y · CIK 0001675881 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,500

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
July 10, 2017 Filed Jul 12, 2017 21:55 UTC
Liu David YChief Scientific Officer
Exercise / conversionEmployee Stock Option (right to buy) · Derivative 3,500 $0.00 Strike: $1.89 $0.00
Disclosure

SEC source: 0001209191-17-044940 · doc4.xml · derivative · entry 3

Liu David Y · CIK 0001675881 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,725

Underlying: Common Stock · 3,500 shares

Expires 2024-10-22

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: The option vests over a four-year period, with 1/4th of the shares subject to the option vesting on the one year anniversary of the vesting commencement date, and 1/36th of the remaining shares subject to the option vesting each month, subject to the Reporting Person continuing to be a service provider of the Issuer through each such date.

Read SEC document
July 10, 2017 Filed Jul 12, 2017 21:55 UTC
Liu David YChief Scientific Officer
SaleCommon Stock 3,500 $12.68 $44,380.00
Disclosure

SEC source: 0001209191-17-044940 · doc4.xml · nonDerivative · entry 2

Liu David Y · CIK 0001675881 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,000

F2 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on February 6, 2017.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $12.36 to $12.84. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
July 10, 2017 Filed Jul 12, 2017 21:55 UTC
Liu David YChief Scientific Officer
Exercise / conversionCommon Stock 3,500 $1.89 $6,615.00
Disclosure

SEC source: 0001209191-17-044940 · doc4.xml · nonDerivative · entry 1

Liu David Y · CIK 0001675881 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,500

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · balance_after: Includes 2,000 shares acquired by the Reporting Person under the Issuer's 2016 Employee Stock Purchase Plan on March 9, 2017.

Read SEC document
June 15, 2017 Filed Jun 15, 2017 23:36 UTC GrantStock Option (right to buy) · Derivative 24,000 $0.00 Strike: $10.84 $0.00
Disclosure

SEC source: 0001209191-17-040261 · doc4.xml · derivative · entry 1

Williams Lewis T · CIK 0001475714 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,000

Underlying: Common Stock · 24,000 shares

Expires 2027-06-15

F1 · derivative.exercise_date: The shares subject to the option shall vest in 36 equal monthly installments from the vesting commencement date of June 15, 2017.

Read SEC document
May 25, 2017 Filed May 26, 2017 17:31 UTC GrantStock Option (right to buy) · Derivative 12,000 $0.00 Strike: $8.59 $0.00
Disclosure

SEC source: 0001209191-17-035964 · doc4.xml · derivative · entry 1

KHOSLA CHAITAN PHD · CIK 0001135139 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,000

Underlying: Common Stock · 12,000 shares

Expires 2027-05-25

F1 · derivative.exercise_date: The shares subject to this option shall vest at the earlier on (i) May 25, 2018, or (ii) the date of the 2018 Annual Meeting of stockholders of the Issuer, subject to the non-employee director's continuous service with the Issuer through such dates. The shares subject to this option will vest in full upon completion of a Change in Control (as defined in the Issuer's 2016 Equity Incentive Plan).

Read SEC document
May 25, 2017 Filed May 26, 2017 17:27 UTC GrantStock Option (right to buy) · Derivative 12,000 $0.00 Strike: $8.59 $0.00
Disclosure

SEC source: 0001209191-17-035958 · doc4.xml · derivative · entry 1

Papanek Julie · CIK 0001673237 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,000

Underlying: Common Stock · 12,000 shares

Expires 2027-05-25

F1 · derivative.exercise_date: The shares subject to this option shall vest at the earlier on (i) May 25, 2018, or (ii) the date of the 2018 Annual Meeting of stockholders of the Issuer, subject to the non-employee director's continuous service with the Issuer through such dates. The shares subject to this option will vest in full upon completion of a Change in Control (as defined in the Issuer's 2016 Equity Incentive Plan).

Read SEC document
May 25, 2017 Filed May 26, 2017 17:35 UTC
Shanafelt ArmenDirector · 10% owner
GrantStock Option (right to buy) · Derivative 12,000 $0.00 Strike: $8.59 $0.00
Disclosure

SEC source: 0001209191-17-035968 · doc4.xml · derivative · entry 1

Shanafelt Armen · CIK 0001656151 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,000

Underlying: Common Stock · 12,000 shares

Expires 2027-05-25

F1 · derivative.exercise_date: The shares subject to this option shall vest at the earlier on (i) May 25, 2018, or (ii) the date of the 2018 Annual Meeting of stockholders of the Issuer, subject to the non-employee director's continuous service with the Issuer through such dates. The shares subject to this option will vest in full upon completion of a Change in Control (as defined in the Issuer's 2016 Equity Incentive Plan).

Read SEC document
May 25, 2017 Filed May 26, 2017 21:37 UTC GrantStock Option (right to buy) · Derivative 12,000 $0.00 Strike: $8.59 $0.00
Disclosure

SEC source: 0001209191-17-035969 · doc4.xml · derivative · entry 1

Waddill William D. · CIK 0001553338 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,000

Underlying: Common Stock · 12,000 shares

Expires 2027-05-25

F1 · derivative.exercise_date: The shares subject to this option shall vest at the earlier on (i) May 25, 2018, or (ii) the date of the 2018 Annual Meeting of stockholders of the Issuer, subject to the non-employee director's continuous service with the Issuer through such dates. The shares subject to this option will vest in full upon completion of a Change in Control (as defined in the Issuer's 2016 Equity Incentive Plan).

Read SEC document
May 25, 2017 Filed May 26, 2017 21:33 UTC GrantStock Option (right to buy) · Derivative 12,000 $0.00 Strike: $8.59 $0.00
Disclosure

SEC source: 0001209191-17-035967 · doc4.xml · derivative · entry 1

SELICK HAROLD E · CIK 0001287233 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,000

Underlying: Common Stock · 12,000 shares

Expires 2027-05-25

F1 · derivative.exercise_date: The shares subject to this option shall vest at the earlier on (i) May 25, 2018, or (ii) the date of the 2018 Annual Meeting of stockholders of the Issuer, subject to the non-employee director's continuous service with the Issuer through such dates. The shares subject to this option will vest in full upon completion of a Change in Control (as defined in the Issuer's 2016 Equity Incentive Plan).

Read SEC document
May 16, 2017 Filed May 17, 2018 21:48 UTC PurchaseCommon Stock 10,000 $6.46 $64,566.00
Disclosure

SEC source: 0001209191-18-031121 · doc4.xml · nonDerivative · entry 1

Giraudo Bryan · CIK 0001740847 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

F1 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $6.43 to $6.50, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the Staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range.

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May 09, 2017 Filed May 11, 2017 00:44 UTC
PATEL DINESH V PH DDirector · President and CEO
Exercise / conversionStock Option (right to buy) · Derivative 19,099 $0.00 Strike: $1.16 $0.00
Disclosure

SEC source: 0001209191-17-031420 · doc4.xml · derivative · entry 2

PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 78,203

Underlying: Common Stock · 19,099 shares

Expires 2025-10-28

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: 1/4th of the shares subject to the option shall vest on the one year anniversary of the vesting commencement date, and 1/36th of the remaining shares subject to the option shall vest on the last day of each month following the first anniversary of the vesting commencement date, subject to the Reporting Person continuing to be a service provider of the Issuer through each such date.

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May 09, 2017 Filed May 11, 2017 00:44 UTC
PATEL DINESH V PH DDirector · President and CEO
Exercise / conversionCommon Stock 19,099 $1.16 $22,154.84
Disclosure

SEC source: 0001209191-17-031420 · doc4.xml · nonDerivative · entry 1

PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 190,437

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

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April 06, 2017 Filed Apr 8, 2017 01:24 UTC
PATEL DINESH V PH DDirector · President and CEO
Exercise / conversionStock Option (right to buy) · Derivative 20,000 $0.00 Strike: $1.16 $0.00
Disclosure

SEC source: 0001209191-17-026368 · doc4.xml · derivative · entry 2

PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 97,302

Underlying: Common Stock · 20,000 shares

Expires 2025-10-28

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: 1/4th of the shares subject to the option shall vest on the one year anniversary of the vesting commencement date, and 1/36th of the remaining shares subject to the option shall vest on the last day of each month following the first anniversary of the vesting commencement date, subject to the Reporting Person continuing to be a service provider of the Issuer through each such date.

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April 06, 2017 Filed Apr 8, 2017 01:24 UTC
PATEL DINESH V PH DDirector · President and CEO
Exercise / conversionCommon Stock 20,000 $1.16 $23,200.00
Disclosure

SEC source: 0001209191-17-026368 · doc4.xml · nonDerivative · entry 1

PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 171,338

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

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March 10, 2017 Filed Mar 13, 2017 23:24 UTC
PATEL DINESH V PH DDirector · President and CEO
Exercise / conversionStock Option (right to buy) · Derivative 16,362 $0.00 Strike: $0.87 $0.00
Disclosure

SEC source: 0001209191-17-020336 · doc4.xml · derivative · entry 2

PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,297

Underlying: Common Stock · 16,362 shares

Expires 2023-09-26

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: 1/4th of the shares subject to the option shall vest on the one year anniversary of the vesting commencement date, and 1/36th of the remaining shares subject to the option shall vest on the last day of each month following the first anniversary of the vesting commencement date, subject to the Reporting Person continuing to be a service provider of the Issuer through each such date.

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March 10, 2017 Filed Mar 13, 2017 23:24 UTC
PATEL DINESH V PH DDirector · President and CEO
Exercise / conversionCommon Stock 16,362 $0.87 $14,234.94
Disclosure

SEC source: 0001209191-17-020336 · doc4.xml · nonDerivative · entry 1

PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 151,338

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
December 22, 2016 Filed Feb 3, 2017 16:37 UTC
PATEL DINESH V PH DDirector · President and CEO
Exercise / conversionStock Option (right to buy) · Derivative 3,000 $0.00 Strike: $0.87 $0.00
Disclosure

SEC source: 0001209191-17-007438 · doc5.xml · derivative · entry 2

PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,659

Underlying: Common Stock · 3,000 shares

Expires 2023-09-26

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: 1/4th of the shares subject to the option shall vest on the one year anniversary of the vesting commencement date, and 1/36th of the remaining shares subject to the option shall vest on the last day of each month following the first anniversary of the vesting commencement date, subject to the Reporting Person continuing to be a service provider of the Issuer through each such date.

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December 22, 2016 Filed Feb 3, 2017 16:37 UTC
PATEL DINESH V PH DDirector · President and CEO
Exercise / conversionCommon Stock 3,000 $0.87 $2,610.00
Disclosure

SEC source: 0001209191-17-007438 · doc5.xml · nonDerivative · entry 1

PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 134,976

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
October 11, 2016 Filed Oct 13, 2016 20:25 UTC
Liu David YChief Scientific Officer
GrantStock Option (right to buy) · Derivative 65,000 $0.00 Strike: $21.58 $0.00
Disclosure

SEC source: 0001209191-16-145800 · doc4.xml · derivative · entry 1

Liu David Y · CIK 0001675881 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 65,000

Underlying: Common Stock · 65,000 shares

Expires 2026-10-11

F1 · derivative.exercise_date: The shares subject to the option shall vest in 48 equal monthly installments from the vesting commencement date of August 10, 2016.

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October 11, 2016 Filed Oct 13, 2016 20:33 UTC
PATEL DINESH V PH DDirector · President and CEO
GrantStock Option (right to buy) · Derivative 320,000 $0.00 Strike: $21.58 $0.00
Disclosure

SEC source: 0001209191-16-145810 · doc4.xml · derivative · entry 1

PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 320,000

Underlying: Common Stock · 320,000 shares

Expires 2026-10-11

F1 · derivative.exercise_date: The shares subject to the option shall vest in 48 equal monthly installments from the vesting commencement date of August 10, 2016.

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October 11, 2016 Filed Oct 13, 2016 16:27 UTC
O'Neil Thomas P.Chief Financial Officer
GrantStock Option (right to buy) · Derivative 45,000 $0.00 Strike: $21.58 $0.00
Disclosure

SEC source: 0001209191-16-145801 · doc4.xml · derivative · entry 1

O'Neil Thomas P. · CIK 0001640645 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,000

Underlying: Common Stock · 45,000 shares

Expires 2026-10-11

F1 · derivative.exercise_date: The shares subject to the option shall vest in 48 equal monthly installments from the vesting commencement date of August 10, 2016.

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October 11, 2016 Filed Oct 13, 2016 20:32 UTC
Shames Richard S.Chief Medical Officer
GrantStock Option (right to buy) · Derivative 65,000 $0.00 Strike: $21.58 $0.00
Disclosure

SEC source: 0001209191-16-145809 · doc4.xml · derivative · entry 1

Shames Richard S. · CIK 0001675878 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 65,000

Underlying: Common Stock · 65,000 shares

Expires 2026-10-11

F1 · derivative.exercise_date: The shares subject to the option shall vest in 48 equal monthly installments from the vesting commencement date of August 10, 2016.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.