PCRX

SEC source: 0001209191-22-004202 · doc4.xml · nonDerivative · entry 3

Williams Kristen Marie · CIK 0001296965 · Chief Administrative Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,581

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The option exercises and sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan previously adopted by the reporting person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934.

SEC source: 0001209191-22-004202 · doc4.xml · nonDerivative · entry 2

Williams Kristen Marie · CIK 0001296965 · Chief Administrative Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,243

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The option exercises and sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan previously adopted by the reporting person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934.

SEC source: 0001209191-22-004202 · doc4.xml · nonDerivative · entry 1

Williams Kristen Marie · CIK 0001296965 · Chief Administrative Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,643

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The option exercises and sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan previously adopted by the reporting person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934.

SEC source: 0001209191-22-004198 · doc4.xml · nonDerivative · entry 1

MOLLOY ANTHONY · CIK 0001900012 · Chief Lgl & Compliance Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,550

F1 · kind: The sale reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan previously adopted by the reporting person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934.

SEC source: 0001209191-22-004200 · doc4.xml · derivative · entry 3

Riker Lauren Bullaro · CIK 0001545439 · Senior Vice President, Finance

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,300

Underlying: Common Stock · 2,500 shares

Expires 2022-06-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vested and became exercisable as to 25% of the option shares on June 5, 2013 and vested as to the remaining shares in successive equal monthly installments for the subsequent 36 months.

SEC source: 0001209191-22-004200 · doc4.xml · nonDerivative · entry 2

Riker Lauren Bullaro · CIK 0001545439 · Senior Vice President, Finance

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,152

F1 · kind: The option exercises and sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan previously adopted by the reporting person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934.

SEC source: 0001209191-22-004200 · doc4.xml · nonDerivative · entry 1

Riker Lauren Bullaro · CIK 0001545439 · Senior Vice President, Finance

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,652

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The option exercises and sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan previously adopted by the reporting person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934.

SEC source: 0001209191-22-003176 · doc4.xml · derivative · entry 5

STACK DAVID M · CIK 0001204788 · Director · CEO and Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 58,670

Underlying: Common Stock · 15,000 shares

Expires 2022-06-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: The option vested and became exercisable as to 25% of the option shares on June 5, 2013 and as to the remaining shares in successive equal monthly installments for the subsequent 36 months.

SEC source: 0001209191-22-003176 · doc4.xml · nonDerivative · entry 1

STACK DAVID M · CIK 0001204788 · Director · CEO and Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 109,374

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · balance_after: Includes 289 shares of common stock acquired under the issuer's employee stock purchase plan in December 2021.

SEC source: 0001209191-22-002726 · doc4.xml · derivative · entry 2

Riker Lauren Bullaro · CIK 0001545439 · Senior Vice President, Finance

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,000

Underlying: Common Stock · 5,000 shares

Expires 2032-01-04

F2 · derivative.exercise_date: The stock option vests and becomes exercisable as to 25% of the option shares on December 7, 2022, and vests as to the remaining shares in successive equal quarterly installments over the subsequent three years, provided that the reporting person remains in continuous service with the issuer as of each vesting date.

SEC source: 0001209191-22-002726 · doc4.xml · nonDerivative · entry 1

Riker Lauren Bullaro · CIK 0001545439 · Senior Vice President, Finance

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,152

F1 · shares: Represents restricted stock units that vest in four equal annual installments beginning on January 2, 2023, provided that the reporting person remains in continuous service with the issuer as of each vesting date. Each restricted stock unit represents the contingent right to receive one share of the issuer's common stock.

SEC source: 0001209191-22-002725 · doc4.xml · derivative · entry 2

MOLLOY ANTHONY · CIK 0001900012 · Chief Lgl & Compliance Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,000

Underlying: Common Stock · 5,000 shares

Expires 2032-01-04

F3 · derivative.exercise_date: The stock option vests and becomes exercisable as to 25% of the option shares on December 7, 2022, and vests as to the remaining shares in successive equal quarterly installments over the subsequent three years, provided that the reporting person remains in continuous service with the issuer as of each vesting date.

SEC source: 0001209191-22-002725 · doc4.xml · nonDerivative · entry 1

MOLLOY ANTHONY · CIK 0001900012 · Chief Lgl & Compliance Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,774

F1 · shares: Represents restricted stock units that vest in four equal annual installments beginning on January 2, 2023, provided that the reporting person remains in continuous service with the issuer as of each vesting date. Each restricted stock unit represents the contingent right to receive one share of the issuer's common stock.

F2 · balance_after: Includes 224 shares of common stock acquired under the issuer's employee stock purchase plan in December 2021.

SEC source: 0001209191-21-070553 · doc4.xml · nonDerivative · entry 1

Froimson Mark · CIK 0001709050 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,908

SEC source: 0001209191-21-066795 · doc4.xml · derivative · entry 2

LARANJEIRA CHARLES ANTHONY · CIK 0001524338 · Chief Technical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 7,500 shares

Expires 2027-06-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The stock option vested and became exercisable as to 25% of the option shares on May 1, 2018, and vested as to the remaining shares in successive equal quarterly installments over the subsequent three years, provided that the reporting person remained in continuous service with the issuer as of each vesting date.

SEC source: 0001209191-21-066795 · doc4.xml · nonDerivative · entry 1

LARANJEIRA CHARLES ANTHONY · CIK 0001524338 · Chief Technical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,602

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · balance_after: Includes 421 shares of common stock acquired under the issuer's employee stock purchase plan in June 2021.

SEC source: 0001209191-21-065463 · doc4.xml · derivative · entry 5

STACK DAVID M · CIK 0001204788 · Director · CEO and Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 73,670

Underlying: Common Stock · 15,000 shares

Expires 2022-06-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: The option vested and became exercisable as to 25% of the option shares on June 5, 2013 and as to the remaining shares in successive equal monthly installments for the subsequent 36 months.

SEC source: 0001209191-21-065463 · doc4.xml · nonDerivative · entry 1

STACK DAVID M · CIK 0001204788 · Director · CEO and Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 94,085

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · balance_after: Includes 129 shares of common stock acquired under the issuer's employee stock purchase plan in June 2021.

SEC source: 0001209191-21-063386 · doc4.xml · derivative · entry 2

WINSTON ROY · CIK 0001751757 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 10,000 shares

Expires 2027-05-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: The stock option vested and became exercisable as to 25% of the option shares on the first anniversary of the grant date, and vested as to the remaining shares in successive equal quarterly installments over the subsequent three years.

SEC source: 0001209191-21-063386 · doc4.xml · nonDerivative · entry 1

WINSTON ROY · CIK 0001751757 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 46,456

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001209191-21-049940 · doc4.xml · derivative · entry 2

SLONIN JONATHAN · CIK 0001875723 · Chief Clinical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Common Stock · 10,000 shares

Expires 2031-07-20

F2 · derivative.exercise_date: The stock option vests and becomes exercisable as to 25% of the option shares on July 20, 2022, and vests as to the remaining shares in successive equal quarterly installments over the subsequent three years, provided that the reporting person remains in continuous service with the issuer as of each vesting date.

SEC source: 0001209191-21-049940 · doc4.xml · nonDerivative · entry 1

SLONIN JONATHAN · CIK 0001875723 · Chief Clinical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,350

F1 · shares: Represents restricted stock units that vest in four equal annual installments beginning on August 1, 2022, provided that the reporting person remains in continuous service with the issuer as of each vesting date. Each restricted stock unit represents the contingent right to receive one share of the issuer's common stock.

SEC source: 0001209191-21-049945 · doc4.xml · derivative · entry 2

WINSTON ROY · CIK 0001751757 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Common Stock · 10,000 shares

Expires 2031-07-20

F3 · derivative.exercise_date: The stock option vests and becomes exercisable as to 25% of the option shares on June 20, 2022, and vests as to the remaining shares in successive equal quarterly installments over the subsequent three years, provided that the reporting person remains in continuous service with the issuer as of each vesting date.

SEC source: 0001209191-21-049945 · doc4.xml · nonDerivative · entry 1

WINSTON ROY · CIK 0001751757 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,456

F1 · shares: Represents restricted stock units that vest in four equal annual installments beginning on August 1, 2022, provided that the reporting person remains in continuous service with the issuer as of each vesting date. Each restricted stock unit represents the contingent right to receive one share of the issuer's common stock.

F2 · balance_after: Includes 421 shares of common stock acquired under the issuer's employee stock purchase plan in June 2021.

SEC source: 0001209191-21-048784 · doc4.xml · derivative · entry 6

Riker Lauren Bullaro · CIK 0001545439 · Vice President, Finance

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,800

Underlying: Common Stock · 90 shares

Expires 2022-06-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: The option vested and became exercisable as to 25% of the option shares on June 5, 2013 and vested as to the remaining shares in successive equal monthly installments for the subsequent 36 months.

SEC source: 0001209191-21-048784 · doc4.xml · nonDerivative · entry 4

Riker Lauren Bullaro · CIK 0001545439 · Vice President, Finance

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,152

F1 · kind: The option exercises and sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan previously adopted by the reporting person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934.

SEC source: 0001209191-21-048784 · doc4.xml · nonDerivative · entry 3

Riker Lauren Bullaro · CIK 0001545439 · Vice President, Finance

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,242

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The option exercises and sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan previously adopted by the reporting person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934.

SEC source: 0001209191-21-048784 · doc4.xml · derivative · entry 5

Riker Lauren Bullaro · CIK 0001545439 · Vice President, Finance

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,890

Underlying: Common Stock · 2,410 shares

Expires 2022-06-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: The option vested and became exercisable as to 25% of the option shares on June 5, 2013 and vested as to the remaining shares in successive equal monthly installments for the subsequent 36 months.

SEC source: 0001209191-21-048784 · doc4.xml · nonDerivative · entry 2

Riker Lauren Bullaro · CIK 0001545439 · Vice President, Finance

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,152

F1 · kind: The option exercises and sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan previously adopted by the reporting person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $60.81 to $60.858, inclusive. The reporting person undertakes to provide to the issuer, any shareholder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001209191-21-048784 · doc4.xml · nonDerivative · entry 1

Riker Lauren Bullaro · CIK 0001545439 · Vice President, Finance

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,562

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The option exercises and sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan previously adopted by the reporting person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934.

F2 · balance_after: Includes 421 shares of common stock acquired under the issuer's employee stock purchase plan in June 2021.

SEC source: 0001209191-21-045622 · doc4.xml · nonDerivative · entry 1

REINHARDT MAX · CIK 0001780058 · President, Rest of World

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,500

F1 · kind: The sale reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan previously adopted by the reporting person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934.

F2 · balance_after: Includes 421 shares of common stock acquired under the issuer's employee stock purchase plan in June 2021.

SEC source: 0001209191-21-040092 · doc4.xml · nonDerivative · entry 2

Riker Lauren Bullaro · CIK 0001545439 · Vice President, Finance

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,731

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $59.820 to $59.845, inclusive. The reporting person undertakes to provide to the issuer, any shareholder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth this footnote.

SEC source: 0001209191-21-040090 · doc4.xml · nonDerivative · entry 3

Williams Kristen Marie · CIK 0001296965 · Chief Administrative Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,268

F2 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan previously adopted by the reporting person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $60.20 to $60.92, inclusive.

SEC source: 0001209191-21-040090 · doc4.xml · nonDerivative · entry 2

Williams Kristen Marie · CIK 0001296965 · Chief Administrative Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,115

F2 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan previously adopted by the reporting person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $59.03 to $59.99, inclusive. The reporting person undertakes to provide to the issuer, any shareholder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes 3 and 4.

SEC source: 0001209191-21-040088 · doc4.xml · derivative · entry 2

Manning Donald C. · CIK 0001775268 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 15,000 shares

Expires 2031-06-09

F2 · derivative.exercise_date: The stock option vests and becomes exercisable as to 25% of the option shares on the first anniversary of the grant date, and vests as to the remaining shares in successive equal quarterly installments over the subsequent three years, provided that the reporting person remains in continuous service with the issuer as of each vesting date.

SEC source: 0001209191-21-040088 · doc4.xml · nonDerivative · entry 1

Manning Donald C. · CIK 0001775268 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,520

F1 · shares: Represents restricted stock units that vest in four equal annual installments beginning on June 3, 2022, provided that the reporting person remains in continuous service with the issuer as of each vesting date. Each restricted stock unit represents the contingent right to receive one share of the issuer's common stock.

SEC source: 0001209191-21-040082 · doc4.xml · derivative · entry 2

Froimson Mark · CIK 0001709050 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,626

Underlying: Common Stock · 7,626 shares

Expires 2031-06-09

SEC source: 0001209191-21-040082 · doc4.xml · nonDerivative · entry 1

Froimson Mark · CIK 0001709050 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,308

F1 · shares: Represents restricted stock units that vest on June 3, 2022, provided that the reporting person remains in continuous service with the issuer through the vesting date. Each restricted stock unit represents the contingent right to receive one share of the issuer's common stock.

SEC source: 0001209191-21-040093 · doc4.xml · derivative · entry 2

Reinhart Charles A. III · CIK 0001470871 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 15,000 shares

Expires 2031-06-09

F2 · derivative.exercise_date: The stock option vests and becomes exercisable as to 25% of the option shares on the first anniversary of the grant date, and vests as to the remaining shares in successive equal quarterly installments over the subsequent three years, provided that the reporting person remains in continuous service with the issuer as of each vesting date.

SEC source: 0001209191-21-040093 · doc4.xml · nonDerivative · entry 1

Reinhart Charles A. III · CIK 0001470871 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,799

F1 · shares: Represents restricted stock units that vest in four equal annual installments beginning on June 3, 2022, provided that the reporting person remains in continuous service with the issuer as of each vesting date. Each restricted stock unit represents the contingent right to receive one share of the issuer's common stock.

SEC source: 0001209191-21-040083 · doc4.xml · derivative · entry 2

Greenstreet Yvonne · CIK 0001446125 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,626

Underlying: Common Stock · 7,626 shares

Expires 2031-06-09

SEC source: 0001209191-21-040083 · doc4.xml · nonDerivative · entry 1

Greenstreet Yvonne · CIK 0001446125 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,087

F1 · shares: Represents restricted stock units that vest on June 3, 2022, provided that the reporting person remains in continuous service with the issuer through the vesting date. Each restricted stock unit represents the contingent right to receive one share of the issuer's common stock.

SEC source: 0001209191-21-040090 · doc4.xml · derivative · entry 4

Williams Kristen Marie · CIK 0001296965 · Chief Administrative Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,500

Underlying: Common Stock · 17,500 shares

Expires 2031-06-09

F5 · derivative.exercise_date: The stock option vests and becomes exercisable as to 25% of the option shares on the first anniversary of the grant date, and vests as to the remaining shares in successive equal quarterly installments over the subsequent three years, provided that the reporting person remains in continuous service with the issuer as of each vesting date.

SEC source: 0001209191-21-040090 · doc4.xml · nonDerivative · entry 1

Williams Kristen Marie · CIK 0001296965 · Chief Administrative Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,957

F1 · shares: Represents restricted stock units that vest in four equal annual installments beginning on June 3, 2022, provided that the reporting person remains in continuous service with the issuer as of each vesting date. Each restricted stock unit represents the contingent right to receive one share of the issuer's common stock.

SEC source: 0001209191-21-040087 · doc4.xml · derivative · entry 2

LONGENECKER JOHN P PHD · CIK 0001288231 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,626

Underlying: Common Stock · 7,626 shares

Expires 2031-06-09

SEC source: 0001209191-21-040087 · doc4.xml · nonDerivative · entry 1

LONGENECKER JOHN P PHD · CIK 0001288231 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,823

F1 · shares: Represents restricted stock units that vest on June 3, 2022, provided that the reporting person remains in continuous service with the issuer through the vesting date. Each restricted stock unit represents the contingent right to receive one share of the issuer's common stock.

SEC source: 0001209191-21-040091 · doc4.xml · derivative · entry 5

STACK DAVID M · CIK 0001204788 · Director · CEO and Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 133,400

Underlying: Common Stock · 133,400 shares

Expires 2031-06-09

F3 · derivative.exercise_date: The stock option vests and becomes exercisable as to 25% of the option shares on the first anniversary of the grant date, and vests as to the remaining shares in successive equal quarterly installments over the subsequent three years, provided that the reporting person remains in continuous service with the issuer as of each vesting date.

SEC source: 0001209191-21-040091 · doc4.xml · nonDerivative · entry 1

STACK DAVID M · CIK 0001204788 · Director · CEO and Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 78,956

F1 · shares: Represents restricted stock units that vest in four equal annual installments beginning on June 3, 2022, provided that the reporting person remains in continuous service with the issuer as of each vesting date. Each restricted stock unit represents the contingent right to receive one share of the issuer's common stock.

SEC source: 0001209191-21-040097 · doc4.xml · derivative · entry 3

PACE GARY W · CIK 0001184778 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,626

Underlying: Common Stock · 7,626 shares

Expires 2031-06-09

SEC source: 0001209191-21-040097 · doc4.xml · nonDerivative · entry 2

PACE GARY W · CIK 0001184778 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 129,530

F1 · shares: Represents restricted stock units that vest on June 3, 2022, provided that the reporting person remains in continuous service with the issuer through the vesting date. Each restricted stock unit represents the contingent right to receive one share of the issuer's common stock.