OMER

SEC source: 0001437749-26-031169 · rdgdoc.xml · derivative · entry 8

Borges David J. · CIK 0002005787 · VP, Finance & CAO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 5,000

Underlying: Common Stock · 10,000 shares

Expires 2030-06-07

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: This option vested and became exercisable with respect to 25% of the total number of shares subject to the option on the 12-month anniversary of the vesting commencement date of June 8, 2020, and the remainder of the option vested and became exercisable over 48 equal installments on each monthly anniversary thereafter.

SEC source: 0001437749-26-031169 · rdgdoc.xml · nonDerivative · entry 5

Borges David J. · CIK 0002005787 · VP, Finance & CAO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

F1 · kind: Open market sale pursuant to a previously established Rule 10b5-1 trading plan adopted by the reporting person on February 10, 2026. The trading schedule, including sale periods and the number of shares to be sold, was established at the time of the trading plan's adoption in accordance with Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

SEC source: 0001437749-26-031169 · rdgdoc.xml · nonDerivative · entry 4

Borges David J. · CIK 0002005787 · VP, Finance & CAO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 10,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001437749-26-031169 · rdgdoc.xml · derivative · entry 7

Borges David J. · CIK 0002005787 · VP, Finance & CAO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 5,000 shares

Expires 2033-09-21

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: This option vests and becomes exercisable over 48 equal monthly installments, with a vesting commencement date of April 1, 2023. Installments vest and become exercisable on each monthly anniversary thereafter.

SEC source: 0001437749-26-031169 · rdgdoc.xml · derivative · entry 6

Borges David J. · CIK 0002005787 · VP, Finance & CAO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 4,094

Underlying: Common Stock · 5,000 shares

Expires 2032-09-20

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: This option vested and became exercisable over 48 equal monthly installments, with a vesting commencement date of April 1, 2022. Installments vested and became exercisable on each monthly anniversary thereafter.

SEC source: 0001437749-26-031169 · rdgdoc.xml · nonDerivative · entry 3

Borges David J. · CIK 0002005787 · VP, Finance & CAO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

F1 · kind: Open market sale pursuant to a previously established Rule 10b5-1 trading plan adopted by the reporting person on February 10, 2026. The trading schedule, including sale periods and the number of shares to be sold, was established at the time of the trading plan's adoption in accordance with Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

SEC source: 0001437749-26-031169 · rdgdoc.xml · nonDerivative · entry 2

Borges David J. · CIK 0002005787 · VP, Finance & CAO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 10,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001437749-26-031169 · rdgdoc.xml · nonDerivative · entry 1

Borges David J. · CIK 0002005787 · VP, Finance & CAO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 5,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001437749-26-029427 · rdgdoc.xml · derivative · entry 6

Cancelmo Peter B · CIK 0001778968 · VP, General Counsel

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 50,000

Underlying: Common Stock · 25,000 shares

Expires 2033-09-22

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: This option shall vest and become exercisable over 48 equal monthly installments, with a vesting commencement date of April 1, 2023. Installments vest and become exercisable on each monthly anniversary thereafter.

SEC source: 0001437749-26-029427 · rdgdoc.xml · nonDerivative · entry 4

Cancelmo Peter B · CIK 0001778968 · VP, General Counsel

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 200

F2 · price: This transaction was executed in multiple trades at prices ranging from $18.32 to $18.90. The price reported above reflects the weighted average sales price. The reporting person hereby undertakes to provide full information regarding the number of shares and prices at which the transactions referenced in this footnote were effected upon request to the SEC staff, the issuer, or a security holder of the issuer.

SEC source: 0001437749-26-029427 · rdgdoc.xml · nonDerivative · entry 3

Cancelmo Peter B · CIK 0001778968 · VP, General Counsel

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 25,200

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001437749-26-029427 · rdgdoc.xml · derivative · entry 5

Cancelmo Peter B · CIK 0001778968 · VP, General Counsel

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 75,000

Underlying: Common Stock · 25,000 shares

Expires 2033-09-22

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: This option shall vest and become exercisable over 48 equal monthly installments, with a vesting commencement date of April 1, 2023. Installments vest and become exercisable on each monthly anniversary thereafter.

SEC source: 0001437749-26-029427 · rdgdoc.xml · nonDerivative · entry 2

Cancelmo Peter B · CIK 0001778968 · VP, General Counsel

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 200

F1 · price: This transaction was executed in multiple trades at prices ranging from $18.55 to $18.77. The price reported above reflects the weighted average sales price. The reporting person hereby undertakes to provide full information regarding the number of shares and prices at which the transactions referenced in this footnote were effected upon request to the SEC staff, the issuer, or a security holder of the issuer.

SEC source: 0001437749-26-029427 · rdgdoc.xml · nonDerivative · entry 1

Cancelmo Peter B · CIK 0001778968 · VP, General Counsel

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 25,200

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001437749-26-029191 · rdgdoc.xml · derivative · entry 10

HANISH ARNOLD C · CIK 0001233253 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 7,500 shares

Expires 2030-06-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001437749-26-029191 · rdgdoc.xml · derivative · entry 9

HANISH ARNOLD C · CIK 0001233253 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 2,500 shares

Expires 2031-06-10

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001437749-26-029191 · rdgdoc.xml · nonDerivative · entry 6

HANISH ARNOLD C · CIK 0001233253 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

F3 · price: This transaction was executed in multiple trades at prices ranging from $19.00 to $19.10. The price reported above reflects the weighted average sales price. The reporting person hereby undertakes to provide full information regarding the number of shares and prices at which the transactions referenced in this footnote were effected upon request to the SEC staff, the issuer, or a security holder of the issuer.

SEC source: 0001437749-26-029191 · rdgdoc.xml · nonDerivative · entry 5

HANISH ARNOLD C · CIK 0001233253 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,000

F2 · price: This transaction was executed in multiple trades at prices ranging from $18.85 to $18.92. The price reported above reflects the weighted average sales price. The reporting person hereby undertakes to provide full information regarding the number of shares and prices at which the transactions referenced in this footnote were effected upon request to the SEC staff, the issuer, or a security holder of the issuer.

SEC source: 0001437749-26-029191 · rdgdoc.xml · nonDerivative · entry 4

HANISH ARNOLD C · CIK 0001233253 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001437749-26-029191 · rdgdoc.xml · nonDerivative · entry 3

HANISH ARNOLD C · CIK 0001233253 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,500

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001437749-26-029191 · rdgdoc.xml · derivative · entry 8

HANISH ARNOLD C · CIK 0001233253 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,500

Underlying: Common Stock · 5,000 shares

Expires 2031-06-10

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001437749-26-029191 · rdgdoc.xml · nonDerivative · entry 2

HANISH ARNOLD C · CIK 0001233253 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

F1 · price: This transaction was executed in multiple trades at prices ranging from $18.50 to $18.56. The price reported above reflects the weighted average sales price. The reporting person hereby undertakes to provide full information regarding the number of shares and prices at which the transactions referenced in this footnote were effected upon request to the SEC staff, the issuer, or a security holder of the issuer.

SEC source: 0001437749-26-029191 · rdgdoc.xml · nonDerivative · entry 1

HANISH ARNOLD C · CIK 0001233253 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001437749-26-028951 · rdgdoc.xml · derivative · entry 8

Borges David J. · CIK 0002005787 · VP, Finance & CAO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 20,000

Underlying: Common Stock · 906 shares

Expires 2033-09-21

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: This option vests and becomes exercisable over 48 equal monthly installments, with a vesting commencement date of April 1, 2023. Installments vest and become exercisable on each monthly anniversary thereafter.

SEC source: 0001437749-26-028951 · rdgdoc.xml · nonDerivative · entry 5

Borges David J. · CIK 0002005787 · VP, Finance & CAO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

F1 · kind: Open market sale pursuant to a previously established Rule 10b5-1 trading plan adopted by the reporting person on February 10, 2026. The trading schedule, including sale periods and the number of shares to be sold, was established at the time of the trading plan's adoption in accordance with Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

SEC source: 0001437749-26-028951 · rdgdoc.xml · nonDerivative · entry 4

Borges David J. · CIK 0002005787 · VP, Finance & CAO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 906

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001437749-26-028951 · rdgdoc.xml · derivative · entry 7

Borges David J. · CIK 0002005787 · VP, Finance & CAO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 20,906

Underlying: Common Stock · 4,094 shares

Expires 2033-09-21

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: This option vests and becomes exercisable over 48 equal monthly installments, with a vesting commencement date of April 1, 2023. Installments vest and become exercisable on each monthly anniversary thereafter.

SEC source: 0001437749-26-028951 · rdgdoc.xml · derivative · entry 6

Borges David J. · CIK 0002005787 · VP, Finance & CAO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 9,094

Underlying: Common Stock · 5,906 shares

Expires 2032-09-20

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: This option vests and becomes exercisable over 48 equal monthly installments, with a vesting commencement date of April 1, 2022. Installments vest and become exercisable on each monthly anniversary thereafter.

SEC source: 0001437749-26-028951 · rdgdoc.xml · nonDerivative · entry 3

Borges David J. · CIK 0002005787 · VP, Finance & CAO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

F1 · kind: Open market sale pursuant to a previously established Rule 10b5-1 trading plan adopted by the reporting person on February 10, 2026. The trading schedule, including sale periods and the number of shares to be sold, was established at the time of the trading plan's adoption in accordance with Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

SEC source: 0001437749-26-028951 · rdgdoc.xml · nonDerivative · entry 2

Borges David J. · CIK 0002005787 · VP, Finance & CAO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 10,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001437749-26-028951 · rdgdoc.xml · nonDerivative · entry 1

Borges David J. · CIK 0002005787 · VP, Finance & CAO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 5,906

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001437749-26-028754 · rdgdoc.xml · derivative · entry 5

Cable Thomas J. · CIK 0001472158 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 7,500 shares

Expires 2032-09-21

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001437749-26-028754 · rdgdoc.xml · derivative · entry 4

Cable Thomas J. · CIK 0001472158 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 7,500 shares

Expires 2032-06-17

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001437749-26-028754 · rdgdoc.xml · nonDerivative · entry 3

Cable Thomas J. · CIK 0001472158 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 35,067

F1 · price: This transaction was executed in multiple trades at prices ranging from $18.23 to $18.72. The price reported above reflects the weighted average sales price. The reporting person hereby undertakes to provide full information regarding the number of shares and prices at which the transactions referenced in this footnote were effected upon request to the SEC staff, the issuer, or a security holder of the issuer.

SEC source: 0001437749-26-028754 · rdgdoc.xml · nonDerivative · entry 2

Cable Thomas J. · CIK 0001472158 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 50,067

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001437749-26-028754 · rdgdoc.xml · nonDerivative · entry 1

Cable Thomas J. · CIK 0001472158 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 42,567

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001437749-26-028229 · rdgdoc.xml · derivative · entry 3

Borges David J. · CIK 0002005787 · VP, Finance & CAO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 5,000 shares

Expires 2032-09-20

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: This option vests and becomes exercisable over 48 equal monthly installments, with a vesting commencement date of April 1, 2022. Installments vest and become exercisable on each monthly anniversary thereafter.

SEC source: 0001437749-26-028229 · rdgdoc.xml · nonDerivative · entry 2

Borges David J. · CIK 0002005787 · VP, Finance & CAO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

F1 · kind: Open market sale pursuant to a previously established Rule 10b5-1 trading plan adopted by the reporting person on February 10, 2026. The trading schedule, including sale periods and the number of shares to be sold, was established at the time of the trading plan's adoption in accordance with Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

SEC source: 0001437749-26-028229 · rdgdoc.xml · nonDerivative · entry 1

Borges David J. · CIK 0002005787 · VP, Finance & CAO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 5,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001437749-26-028463 · rdgdoc.xml · derivative · entry 1

Schocken Joseph L · CIK 0001362618 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 30,000

Underlying: Common Stock · 30,000 shares

Expires 2036-08-11

F1 · derivative.exercise_date: This option shall vest and become exercisable in equal annual installments over a three-year period beginning on the first anniversary of the date of grant.

SEC source: 0001437749-26-024439 · rdgdoc.xml · derivative · entry 1

Borges David J. · CIK 0002005787 · VP, Finance & CAO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 105,000

Underlying: Common Stock · 105,000 shares

Expires 2036-07-22

F1 · derivative.exercise_date: One-third of the total number of shares subject to the option will vest and become exercisable on August 1, 2027. The remaining shares shall vest in 32 equal monthly installments on the first day of each month thereafter.

SEC source: 0001437749-26-024441 · rdgdoc.xml · derivative · entry 1

Cancelmo Peter B · CIK 0001778968 · VP, General Counsel

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 105,000

Underlying: Common Stock · 105,000 shares

Expires 2036-07-22

F1 · derivative.exercise_date: One-third of the total number of shares subject to the option will vest and become exercisable on August 1, 2027. The remaining shares shall vest in 32 equal monthly installments on the first day of each month thereafter.

SEC source: 0001437749-26-024443 · rdgdoc.xml · derivative · entry 1

Demopulos Gregory A MD · CIK 0001472160 · Director · Chairman, CEO & President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,000,000

Underlying: Common Stock · 1,000,000 shares

Expires 2036-07-22

F1 · derivative.exercise_date: One-third of the total number of shares subject to the option will vest and become exercisable on August 1, 2027. The remaining shares shall vest in 32 equal monthly installments on the first day of each month thereafter.

SEC source: 0001437749-26-021239 · rdgdoc.xml · derivative · entry 1

Perkinson Diana T. · CIK 0001976830 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 15,000 shares

Expires 2036-06-17

F1 · security: Pursuant to Omeros Corporation's non-employee director compensation policy, on the date of each annual meeting of shareholders, each non-employee director who has served as a director for at least six months and who will continue to serve as a director after the annual meeting is automatically granted an option to purchase 15,000 shares of common stock. This Form 4 reports the annual stock option award granted to the reporting person in conjunction with the annual meeting of shareholders held on June 18, 2026.

F2 · derivative.exercise_date: This option will fully vest and become exercisable on the day before the date of the 2027 annual meeting of the shareholders of Omeros Corporation, provided that the reporting person continues to serve as a director of the company through such date.

SEC source: 0001437749-26-021235 · rdgdoc.xml · derivative · entry 1

Cable Thomas J. · CIK 0001472158 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 15,000 shares

Expires 2036-06-17

F1 · security: Pursuant to Omeros Corporation's non-employee director compensation policy, on the date of each annual meeting of shareholders, each non-employee director who has served as a director for at least six months and who will continue to serve as a director after the annual meeting is automatically granted an option to purchase 15,000 shares of common stock. This Form 4 reports the annual stock option award granted to the reporting person in conjunction with the annual meeting of shareholders held on June 18, 2026.

F2 · derivative.exercise_date: This option will fully vest and become exercisable on the day before the date of the 2027 annual meeting of the shareholders of Omeros Corporation, provided that the reporting person continues to serve as a director of the company through such date.

SEC source: 0001437749-26-021240 · rdgdoc.xml · derivative · entry 1

Shah Rajiv · CIK 0001642407 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 15,000 shares

Expires 2036-06-17

F1 · security: Pursuant to Omeros Corporation's non-employee director compensation policy, on the date of each annual meeting of shareholders, each non-employee director who has served as a director for at least six months and who will continue to serve as a director after the annual meeting is automatically granted an option to purchase 15,000 shares of common stock. This Form 4 reports the annual stock option award granted to the reporting person in conjunction with the annual meeting of shareholders held on June 18, 2026.

F2 · derivative.exercise_date: This option will fully vest and become exercisable on the day before the date of the 2027 annual meeting of the shareholders of Omeros Corporation, provided that the reporting person continues to serve as a director of the company through such date.

SEC source: 0001437749-26-021238 · rdgdoc.xml · derivative · entry 1

Hood Leroy E. MD PhD · CIK 0001472162 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 15,000 shares

Expires 2036-06-17

F1 · security: Pursuant to Omeros Corporation's non-employee director compensation policy, on the date of each annual meeting of shareholders, each non-employee director who has served as a director for at least six months and who will continue to serve as a director after the annual meeting is automatically granted an option to purchase 15,000 shares of common stock. This Form 4 reports the annual stock option award granted to the reporting person in conjunction with the annual meeting of shareholders held on June 18, 2026.

F2 · derivative.exercise_date: This option will fully vest and become exercisable on the day before the date of the 2027 annual meeting of the shareholders of Omeros Corporation, provided that the reporting person continues to serve as a director of the company through such date.

SEC source: 0001437749-26-021237 · rdgdoc.xml · derivative · entry 1

HANISH ARNOLD C · CIK 0001233253 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 15,000 shares

Expires 2036-06-17

F1 · security: Pursuant to Omeros Corporation's non-employee director compensation policy, on the date of each annual meeting of shareholders, each non-employee director who has served as a director for at least six months and who will continue to serve as a director after the annual meeting is automatically granted an option to purchase 15,000 shares of common stock. This Form 4 reports the annual stock option award granted to the reporting person in conjunction with the annual meeting of shareholders held on June 18, 2026.

F2 · derivative.exercise_date: This option will fully vest and become exercisable on the day before the date of the 2027 annual meeting of the shareholders of Omeros Corporation, provided that the reporting person continues to serve as a director of the company through such date.

SEC source: 0001437749-26-021236 · rdgdoc.xml · derivative · entry 1

Demopulos Peter A MD · CIK 0001472161 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 15,000 shares

Expires 2036-06-17

F1 · security: Pursuant to Omeros Corporation's non-employee director compensation policy, on the date of each annual meeting of shareholders, each non-employee director who has served as a director for at least six months and who will continue to serve as a director after the annual meeting is automatically granted an option to purchase 15,000 shares of common stock. This Form 4 reports the annual stock option award granted to the reporting person in conjunction with the annual meeting of shareholders held on June 18, 2026.

F2 · derivative.exercise_date: This option will fully vest and become exercisable on the day before the date of the 2027 annual meeting of the shareholders of Omeros Corporation, provided that the reporting person continues to serve as a director of the company through such date.

SEC source: 0001437749-26-021234 · rdgdoc.xml · derivative · entry 1

Bumol Thomas F. · CIK 0001767077 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 15,000 shares

Expires 2036-06-17

F1 · security: Pursuant to Omeros Corporation's non-employee director compensation policy, on the date of each annual meeting of shareholders, each non-employee director who has served as a director for at least six months and who will continue to serve as a director after the annual meeting is automatically granted an option to purchase 15,000 shares of common stock. This Form 4 reports the annual stock option award granted to the reporting person in conjunction with the annual meeting of shareholders held on June 18, 2026.

F2 · derivative.exercise_date: This option will fully vest and become exercisable on the day before the date of the 2027 annual meeting of the shareholders of Omeros Corporation, provided that the reporting person continues to serve as a director of the company through such date.