NPCE

SEC source: 0001209191-21-028199 · doc4.xml · nonDerivative · entry 1

ORBIMED ADVISORS LLC · CIK 0001055951 · 10% owner

OrbiMed Capital GP VI LLC · CIK 0001682115 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 235,000

F1 · shares: Reflects shares purchased from the underwriters in the Companys initial public offering.

F2 · ownership.nature: These shares of the Issuer's common stock are held of record by OrbiMed Privat Investments VI, LP ("OPI VI"). OrbiMed Capital GP VI LLC ("GP VI") is the general partner of OPI VI, and OrbiMed Advisors LLC ("OrbiMed Advisors"), a registered investment adviser under the Investment Advisors Act of 1940, as amended, is the managing member of GP VI. By virtue of such relationships, GP VI and OrbiMed Advisors may be deemed to have voting and investment power with respect to the securities held by OPI VI and, as a result, may be deemed to beneficially own such securities for purposes of Rule 13d-3 under the Securities Exchange Act of 1934, as amended (the "Exchange Act"). OrbiMed Advisors exercises this investment and voting power through a management committee comprised of Carl L. Gordon, Sven H. Borho, and Jonathan T. Silverstein, each of whom disclaims beneficial ownership of the shares held by OPI VI.

F3 · ownership.nature: This report is being jointly filed by OrbiMed Advisors and GP VI. Each of the Reporting Persons disclaims beneficial ownership of the securities reported herein for purposes of Rule 16a-1(a) under the Exchange Act, except to the extent of its pecuniary interest therein, if any. This report shall not be deemed an admission that any of the Reporting Persons are a beneficial owner of such securities for the purpose of Section 16 of the Exchange Act, or for any other purpose.

SEC source: 0001209191-21-028193 · doc4.xml · nonDerivative · entry 1

Ridley Irina · CIK 0001855591 · General Counsel and Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,352

F1 · shares: Reflects shares purchased from the underwriters in the Companys initial public offering.

SEC source: 0001209191-21-028192 · doc4.xml · nonDerivative · entry 1

Accelmed Partners II L.P. · CIK 0001807256 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 588,235

F1 · shares: Reflects shares purchased from the underwriters in the Companys initial public offering.

SEC source: 0001209191-21-028191 · doc4.xml · derivative · entry 2

Fischer Frank M · CIK 0001297260 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,698

Underlying: Common Stock · 21,698 shares

Expires 2031-04-20

F2 · derivative.exercise_date: 1/36th of the shares subject to the option vest in equal monthly installments commencing May 21, 2021.

SEC source: 0001209191-21-028191 · doc4.xml · nonDerivative · entry 1

Fischer Frank M · CIK 0001297260 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 93,291

F1 · shares: Reflects shares purchased from the underwriters in the Companys initial public offering.

SEC source: 0001209191-21-028189 · doc4.xml · derivative · entry 2

Garfield Greg Shaw · CIK 0001594406 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,698

Underlying: Common Stock · 21,698 shares

Expires 2031-04-20

F2 · derivative.exercise_date: 1/36th of the shares subject to the option vest in equal monthly installments commencing May 21, 2021.

SEC source: 0001209191-21-028189 · doc4.xml · nonDerivative · entry 1

Garfield Greg Shaw · CIK 0001594406 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,853

F1 · shares: Reflects shares purchased from the underwriters in the Companys initial public offering.

SEC source: 0001209191-21-028188 · doc4.xml · nonDerivative · entry 1

Norton Evan · CIK 0001856303 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 588,235

F1 · shares: Reflects shares purchased from the underwriters in the Companys initial public offering.

F2 · ownership.nature: Shares are held by Accelmed Partners II LP. Accelmed Partners II, LLC ("Accelmed LLC") is the general partner of Accelmed Partners II GP, L.P., which is the general partner of Accelmed Partners II LP. Uri Geiger is the managing partner of Accelmed LLC and has sole voting and dispositive power with respect to the shares held by Accelmed Partners II LP. Mr. Norton, a member of our board of directors, is a General Partner at Accelmed LLC. The address of each of Accelmed LLC, Accelmed Partners II GP, LP, Accelmed Partners II LP and Mr. Norton is Ugland House, South Church Street, PO Box 309, Grand Cayman KY1-1104, Cayman Islands.

SEC source: 0001209191-21-060107 · doc4.xml · derivative · entry 1

Ryan Renee · CIK 0001855576 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,698

Underlying: Common Stock · 21,698 shares

Expires 2031-04-20

F1 · derivative.exercise_date: 1/36th of the shares subject to the option vest in equal monthly installments commencing May 21, 2021.

SEC source: 0001209191-21-060103 · doc4.xml · derivative · entry 1

LACOB JOSEPH · CIK 0001215490 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,698

Underlying: Common Stock · 21,698 shares

Expires 2031-04-20

F1 · derivative.exercise_date: 1/36th of the shares subject to the option vest in equal monthly installments commencing May 21, 2021.

SEC source: 0001209191-21-060106 · doc4.xml · derivative · entry 1

Norton Evan · CIK 0001856303 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,698

Underlying: Common Stock · 21,698 shares

Expires 2031-04-20

F1 · derivative.exercise_date: 1/36th of the shares subject to the option vest in equal monthly installments commencing May 21, 2021.

SEC source: 0001209191-21-060105 · doc4.xml · derivative · entry 1

Kumar Rakhi · CIK 0001856296 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,698

Underlying: Common Stock · 21,698 shares

Expires 2031-04-20

F1 · derivative.exercise_date: 1/36th of the shares subject to the option vest in equal monthly installments commencing May 21, 2021.