Last 12 months
Inside the activity.
1 purchase rows · 7 sale rows
Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.Monthly counts
| Month | Purchases | Sales |
|---|---|---|
| Nov 2025 | 0 | 0 |
| Dec 2025 | 0 | 0 |
| Jan 2026 | 0 | 0 |
| Feb 2026 | 0 | 0 |
| Mar 2026 | 0 | 0 |
| Apr 2026 | 1 | 0 |
| May 2026 | 0 | 1 |
| Jun 2026 | 0 | 2 |
| Jul 2026 | 0 | 1 |
| Aug 2026 | 0 | 1 |
| Sep 2026 | 0 | 2 |
| Oct 2026 | 0 | 0 |
Latest available
Insider transactions
Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”
The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.
| Transaction date | Owner / reported role | Activity / security | Shares / units | Reported price | Reported value | Details |
|---|---|---|---|---|---|---|
| September 18, 2026 Filed Sep 21, 2026 20:05 UTC |
Dennis Phillip AndrewChief Medical Officer
|
SaleOrdinary Shares | 8,209 | $0.71 | $5,828.39 |
DisclosureSEC source: 0002089237-26-000008 · form4-09212026_040901.xml · nonDerivative · entry 2 Dennis Phillip Andrew · CIK 0002089237 · Chief Medical Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 173,427 F1 · security: The Ordinary Shares may be represented by American Depositary Shares ("ADS"). Each 10 ADSs represent 23 Ordinary Shares of the Issuer. F5 · shares: Reported securities are represented by 3,569 ADSs. F6 · price: Reported sales price represents the converted sales price of the ADSs of $1.6247. F7 · balance_after: Reported securities are represented by 75,403 ADSs. Read SEC document |
| September 17, 2026 Filed Sep 21, 2026 20:05 UTC |
Dennis Phillip AndrewChief Medical Officer
|
Exercise / conversionRestricted Share Units · Derivative | 10,302 | $0.00 | $0.00 |
DisclosureSEC source: 0002089237-26-000008 · form4-09212026_040901.xml · derivative · entry 3 Dennis Phillip Andrew · CIK 0002089237 · Chief Medical Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 72,120 Underlying: Ordinary Shares · 10,302 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F3 · derivative.exercise_price: Each restricted stock unit ("RSU") represents a contingent right to receive one ADS. F8 · shares: Reported securities represent ADSs. F9 · derivative.exercise_date: On June 17, 2024, the Reporting Person was granted 164,840 RSUs. The RSUs vested or shall vest over four years, with one-fourth vesting on the first anniversary of the grant date and the balance vesting ratably over the subsequent 12 quarters on the 17th day of each third month. F9 · derivative.expiration_date: On June 17, 2024, the Reporting Person was granted 164,840 RSUs. The RSUs vested or shall vest over four years, with one-fourth vesting on the first anniversary of the grant date and the balance vesting ratably over the subsequent 12 quarters on the 17th day of each third month. F1 · derivative.underlying: The Ordinary Shares may be represented by American Depositary Shares ("ADS"). Each 10 ADSs represent 23 Ordinary Shares of the Issuer. F8 · derivative.underlying_shares: Reported securities represent ADSs. F8 · balance_after: Reported securities represent ADSs. Read SEC document |
| September 17, 2026 Filed Sep 21, 2026 20:05 UTC |
Dennis Phillip AndrewChief Medical Officer
|
Exercise / conversionOrdinary Shares | 23,695 | Not disclosed | Not disclosed |
DisclosureSEC source: 0002089237-26-000008 · form4-09212026_040901.xml · nonDerivative · entry 1 Dennis Phillip Andrew · CIK 0002089237 · Chief Medical Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 181,636 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · security: The Ordinary Shares may be represented by American Depositary Shares ("ADS"). Each 10 ADSs represent 23 Ordinary Shares of the Issuer. F2 · shares: Reported securities are represented by 10,302 ADSs. F3 · price: Each restricted stock unit ("RSU") represents a contingent right to receive one ADS. F4 · balance_after: Reported securities are represented by 78,972 ADSs. Read SEC document |
| September 09, 2026 Filed Sep 11, 2026 20:30 UTC |
Cao Sean WuxiongChief Bus. Development Officer
|
SaleOrdinary Shares | 107,978 | $0.74 | $79,903.72 |
DisclosureSEC source: 0002109966-26-000008 · form4-09112026_040901.xml · nonDerivative · entry 1 Cao Sean Wuxiong · CIK 0002109966 · Chief Bus. Development Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 266,467 F1 · security: The Ordinary Shares may be represented by American Depositary Shares ("ADS"). Each 10 ADSs represent 23 Ordinary Shares of the Issuer. F2 · kind: The Reporting Person sold 46,947 ADSs representing approximately 107,978 ordinary shares in connection with the partial vesting of a restricted stock unit award on September 3, 2026, solely to satisfy tax withholding obligations incurred in connection with the vesting. F3 · shares: Reported securities are represented by 46,947 ADSs. F4 · price: Reported sales price represents the converted sales price of the ADSs of $1.6908. Read SEC document |
| September 03, 2026 Filed Sep 8, 2026 21:51 UTC |
Cao Sean WuxiongChief Bus. Development Officer
|
Exercise / conversionRestricted Share Units · Derivative | 45,320 | $0.00 | $0.00 |
DisclosureSEC source: 0002109966-26-000006 · form4-09082026_090957.xml · derivative · entry 4 Cao Sean Wuxiong · CIK 0002109966 · Chief Bus. Development Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 135,960 Underlying: Ordinary Shares · 45,320 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F3 · derivative.exercise_price: Each restricted stock unit ("RSU") represents a contingent right to receive one ADS. F6 · derivative.exercise_date: On June 22, 2026, the Reporting Person was granted 181,280 RSUs. The RSUs vested or shall vest over four years, with one-fourth vesting on September 3, 2026 and the balance vesting ratably over the subsequent 12 quarters on the third day of each third month. F6 · derivative.expiration_date: On June 22, 2026, the Reporting Person was granted 181,280 RSUs. The RSUs vested or shall vest over four years, with one-fourth vesting on September 3, 2026 and the balance vesting ratably over the subsequent 12 quarters on the third day of each third month. F1 · derivative.underlying: The Ordinary Shares may be represented by American Depositary Shares ("ADS"). Each 10 ADSs represent 23 Ordinary Shares of the Issuer. Read SEC document |
| September 03, 2026 Filed Sep 8, 2026 21:51 UTC |
Cao Sean WuxiongChief Bus. Development Officer
|
Exercise / conversionRestricted Share Units · Derivative | 102,233 | $0.00 | $0.00 |
DisclosureSEC source: 0002109966-26-000006 · form4-09082026_090957.xml · derivative · entry 3 Cao Sean Wuxiong · CIK 0002109966 · Chief Bus. Development Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 306,700 Underlying: Ordinary Shares · 102,233 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F3 · derivative.exercise_price: Each restricted stock unit ("RSU") represents a contingent right to receive one ADS. F5 · derivative.exercise_date: On September 3, 2025, the Reporting Person was granted 408,933 RSUs. The RSUs vested or shall vest over four years, with one-fourth vesting on the first anniversary of the grant date and the balance vesting ratably over the subsequent 12 quarters on the third day of each third month. F5 · derivative.expiration_date: On September 3, 2025, the Reporting Person was granted 408,933 RSUs. The RSUs vested or shall vest over four years, with one-fourth vesting on the first anniversary of the grant date and the balance vesting ratably over the subsequent 12 quarters on the third day of each third month. F1 · derivative.underlying: The Ordinary Shares may be represented by American Depositary Shares ("ADS"). Each 10 ADSs represent 23 Ordinary Shares of the Issuer. Read SEC document |
| September 03, 2026 Filed Sep 8, 2026 21:51 UTC |
Cao Sean WuxiongChief Bus. Development Officer
|
Exercise / conversionOrdinary Shares | 104,236 | Not disclosed | Not disclosed |
DisclosureSEC source: 0002109966-26-000006 · form4-09082026_090957.xml · nonDerivative · entry 2 Cao Sean Wuxiong · CIK 0002109966 · Chief Bus. Development Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 374,445 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · security: The Ordinary Shares may be represented by American Depositary Shares ("ADS"). Each 10 ADSs represent 23 Ordinary Shares of the Issuer. F4 · shares: Reported securities are represented by 45,320 ADSs. F3 · price: Each restricted stock unit ("RSU") represents a contingent right to receive one ADS. Read SEC document |
| September 03, 2026 Filed Sep 8, 2026 21:51 UTC |
Cao Sean WuxiongChief Bus. Development Officer
|
Exercise / conversionOrdinary Shares | 235,136 | Not disclosed | Not disclosed |
DisclosureSEC source: 0002109966-26-000006 · form4-09082026_090957.xml · nonDerivative · entry 1 Cao Sean Wuxiong · CIK 0002109966 · Chief Bus. Development Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 270,209 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · security: The Ordinary Shares may be represented by American Depositary Shares ("ADS"). Each 10 ADSs represent 23 Ordinary Shares of the Issuer. F2 · shares: Reported securities are represented by 102,233 ADSs F3 · price: Each restricted stock unit ("RSU") represents a contingent right to receive one ADS. Read SEC document |
| August 31, 2026 Filed Sep 1, 2026 22:00 UTC |
Xu Cong ClaireEVP, Clinical Development
|
SaleOrdinary Shares | 3,282 | $0.79 | $2,592.78 |
DisclosureSEC source: 0002114309-26-000007 · form4-09012026_060901.xml · nonDerivative · entry 2 Xu Cong Claire · CIK 0002114309 · EVP, Clinical Development 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 304,201 F1 · security: The Ordinary Shares may be represented by American Depositary Shares ("ADS"). Each 10 ADSs represent 23 Ordinary Shares of the Issuer. F5 · shares: Reported securities are represented by 1,427 ADSs. F6 · price: Reported sales price represents the converted sales price of the ADSs of $1.8186. F7 · balance_after: Reported securities are represented by 132,261 ADSs. Read SEC document |
| August 30, 2026 Filed Sep 1, 2026 22:00 UTC |
Xu Cong ClaireEVP, Clinical Development
|
Exercise / conversionRestricted Share Units · Derivative | 4,079 | $0.00 | $0.00 |
DisclosureSEC source: 0002114309-26-000007 · form4-09012026_060901.xml · derivative · entry 3 Xu Cong Claire · CIK 0002114309 · EVP, Clinical Development 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 28,558 Underlying: Ordinary Shares · 4,079 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F3 · derivative.exercise_price: Each restricted stock unit ("RSU") represents a contingent right to receive one ADS. F8 · shares: Reported securities represent ADSs. F9 · derivative.exercise_date: On May 30, 2024, the Reporting Person was granted 65,270 RSUs. The RSUs vested or shall vest over four years, with one-fourth vesting on the first anniversary of the grant date and the balance vesting ratably over the subsequent 12 quarters on the 30th day of each third month. F9 · derivative.expiration_date: On May 30, 2024, the Reporting Person was granted 65,270 RSUs. The RSUs vested or shall vest over four years, with one-fourth vesting on the first anniversary of the grant date and the balance vesting ratably over the subsequent 12 quarters on the 30th day of each third month. F1 · derivative.underlying: The Ordinary Shares may be represented by American Depositary Shares ("ADS"). Each 10 ADSs represent 23 Ordinary Shares of the Issuer. F8 · derivative.underlying_shares: Reported securities represent ADSs. Read SEC document |
| August 30, 2026 Filed Sep 1, 2026 22:00 UTC |
Xu Cong ClaireEVP, Clinical Development
|
Exercise / conversionOrdinary Shares | 9,382 | Not disclosed | Not disclosed |
DisclosureSEC source: 0002114309-26-000007 · form4-09012026_060901.xml · nonDerivative · entry 1 Xu Cong Claire · CIK 0002114309 · EVP, Clinical Development 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 307,483 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · security: The Ordinary Shares may be represented by American Depositary Shares ("ADS"). Each 10 ADSs represent 23 Ordinary Shares of the Issuer. F2 · shares: Reported securities are represented by 4,079 ADSs. F3 · price: Each restricted stock unit ("RSU") represents a contingent right to receive one ADS. F4 · balance_after: Reported securities are represented by 133,688 ADSs. Read SEC document |
| August 22, 2026 Filed Aug 25, 2026 20:15 UTC |
Lenz Robert A.Director
|
Exercise / conversionRestricted Share Units · Derivative | 7,486 | $0.00 | $0.00 |
DisclosureSEC source: 0001992908-26-000013 · form4-08252026_040807.xml · derivative · entry 2 Lenz Robert A. · CIK 0001992908 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 14,974 Underlying: Ordinary Shares · 7,486 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F3 · derivative.exercise_price: Each restricted stock unit ("RSU") represents a contingent right to receive one ADS. F4 · shares: Reported securities represent ADSs. F5 · derivative.exercise_date: On August 22, 2025, the Reporting Person was granted 22,460 restricted share units ("RSUs"). The RSUs vested or shall vest over three years in three equal annual installments on August 22, 2026, 2027 and 2028. F5 · derivative.expiration_date: On August 22, 2025, the Reporting Person was granted 22,460 restricted share units ("RSUs"). The RSUs vested or shall vest over three years in three equal annual installments on August 22, 2026, 2027 and 2028. F4 · balance_after: Reported securities represent ADSs. Read SEC document |
| August 22, 2026 Filed Aug 25, 2026 20:15 UTC |
Lenz Robert A.Director
|
Exercise / conversionOrdinary Shares | 17,218 | Not disclosed | Not disclosed |
DisclosureSEC source: 0001992908-26-000013 · form4-08252026_040807.xml · nonDerivative · entry 1 Lenz Robert A. · CIK 0001992908 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 17,218 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · security: The Ordinary Shares may be represented by American Depositary Shares ("ADS"). Each 10 ADSs represent 23 Ordinary Shares of the Issuer. F2 · shares: Reported securities are represented by 7,486 ADSs. F3 · price: Each restricted stock unit ("RSU") represents a contingent right to receive one ADS. F2 · balance_after: Reported securities are represented by 7,486 ADSs. Read SEC document |
| July 08, 2026 Filed Jul 10, 2026 21:00 UTC |
Hagler Mark ArnoldChief Commercial Officer
|
Grant2025 Employee Share Option (right to buy) · Derivative | 949,050 | $0.00 Strike: $1.93 | $0.00 |
DisclosureSEC source: 0002126029-26-000003 · form4-07102026_050705.xml · derivative · entry 1 Hagler Mark Arnold · CIK 0002126029 · Chief Commercial Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 949,050 Underlying: Ordinary Shares · 949,050 shares Expires 2036-07-08 F1 · derivative.exercise_price: Number of underlying securities and exercise price expressed in terms of American Depositary Shares ("ADS"). F1 · shares: Number of underlying securities and exercise price expressed in terms of American Depositary Shares ("ADS"). F2 · derivative.exercise_date: The option vests and becomes exercisable in four equal annual installments beginning on the first anniversary of April 17, 2026. F3 · derivative.underlying: The Ordinary Shares may be represented by ADSs. Each 10 ADSs represent 23 Ordinary Shares of the Issuer. F1 · derivative.underlying_shares: Number of underlying securities and exercise price expressed in terms of American Depositary Shares ("ADS"). F1 · balance_after: Number of underlying securities and exercise price expressed in terms of American Depositary Shares ("ADS"). Read SEC document |
| July 08, 2026 Filed Jul 10, 2026 21:00 UTC |
Lin Liwei LorraineGeneral Counsel
|
Grant2025 Employee Share Option (right to buy) · Derivative | 254,780 | $0.00 Strike: $1.93 | $0.00 |
DisclosureSEC source: 0002114156-26-000003 · form4-07102026_050707.xml · derivative · entry 1 Lin Liwei Lorraine · CIK 0002114156 · General Counsel 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 254,780 Underlying: Ordinary Shares · 254,780 shares Expires 2036-07-08 F1 · derivative.exercise_price: Number of underlying securities and exercise price expressed in terms of American Depositary Shares ("ADS"). F1 · shares: Number of underlying securities and exercise price expressed in terms of American Depositary Shares ("ADS"). F2 · derivative.exercise_date: The option vests and becomes exercisable over five years, with 40% vesting on the second anniversary of February 1, 2026 and the balance vesting in three equal annual installments thereafter. F3 · derivative.underlying: The Ordinary Shares may be represented by ADSs. Each 10 ADSs represent 23 Ordinary Shares of the Issuer. F1 · derivative.underlying_shares: Number of underlying securities and exercise price expressed in terms of American Depositary Shares ("ADS"). F1 · balance_after: Number of underlying securities and exercise price expressed in terms of American Depositary Shares ("ADS"). Read SEC document |
| July 06, 2026 Filed Jul 7, 2026 23:50 UTC |
Xu Cong ClaireSVP, Clinical Development
|
SaleOrdinary Shares | 4,485 | $0.89 | $3,991.65 |
DisclosureSEC source: 0002114309-26-000005 · form4-07072026_110715.xml · nonDerivative · entry 2 Xu Cong Claire · CIK 0002114309 · SVP, Clinical Development 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 298,101 F1 · security: The Ordinary Shares may be represented by American Depositary Shares ("ADS"). Each 10 ADSs represent 23 Ordinary Shares of the Issuer. F5 · shares: Reported securities are represented by 1,950 ADSs. F6 · price: Reported sales price represents the converted sales price of the ADSs of $2.04. F7 · balance_after: Reported securities are represented by 129,609 ADSs. Read SEC document |
| July 06, 2026 Filed Jul 8, 2026 20:26 UTC |
Gupta SrishtiDirector · Chief Executive Officer
|
Grant2025 Employee Share Option (right to buy) · Derivative | 3,000,000 | $0.00 Strike: $2.01 | $0.00 |
DisclosureSEC source: 0002024011-26-000006 · form4-07082026_080720.xml · derivative · entry 1 Gupta Srishti · CIK 0002024011 · Director · Chief Executive Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 3,000,000 Underlying: Ordinary Shares · 3,000,000 shares Expires 2036-07-06 F1 · derivative.exercise_price: Number of underlying securities and exercise price expressed in terms of American Depositary Shares ("ADS"). F1 · shares: Number of underlying securities and exercise price expressed in terms of American Depositary Shares ("ADS"). F2 · derivative.exercise_date: The option vests and becomes exercisable in four equal annual installments beginning on the first anniversary of July 1, 2026. F3 · derivative.underlying: The Ordinary Shares may be represented by ADSs. Each 10 ADSs represent 23 Ordinary Shares of the Issuer. F1 · derivative.underlying_shares: Number of underlying securities and exercise price expressed in terms of American Depositary Shares ("ADS"). F1 · balance_after: Number of underlying securities and exercise price expressed in terms of American Depositary Shares ("ADS"). Read SEC document |
| July 04, 2026 Filed Jul 7, 2026 23:50 UTC |
Xu Cong ClaireSVP, Clinical Development
|
Exercise / conversionRestricted Share Units · Derivative | 5,405 | $0.00 | $0.00 |
DisclosureSEC source: 0002114309-26-000005 · form4-07072026_110715.xml · derivative · entry 3 Xu Cong Claire · CIK 0002114309 · SVP, Clinical Development 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 0 Underlying: Ordinary Shares · 5,405 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F3 · derivative.exercise_price: Each restricted stock unit ("RSU") represents a contingent right to receive one ADS. F8 · shares: Reported securities represent ADSs. F9 · derivative.exercise_date: Fully vested. F9 · derivative.expiration_date: Fully vested. F1 · derivative.underlying: The Ordinary Shares may be represented by American Depositary Shares ("ADS"). Each 10 ADSs represent 23 Ordinary Shares of the Issuer. F8 · derivative.underlying_shares: Reported securities represent ADSs. F8 · balance_after: Reported securities represent ADSs. Read SEC document |
| July 04, 2026 Filed Jul 7, 2026 23:50 UTC |
Xu Cong ClaireSVP, Clinical Development
|
Exercise / conversionOrdinary Shares | 12,432 | Not disclosed | Not disclosed |
DisclosureSEC source: 0002114309-26-000005 · form4-07072026_110715.xml · nonDerivative · entry 1 Xu Cong Claire · CIK 0002114309 · SVP, Clinical Development 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 302,586 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · security: The Ordinary Shares may be represented by American Depositary Shares ("ADS"). Each 10 ADSs represent 23 Ordinary Shares of the Issuer. F2 · shares: Reported securities are represented by 5,405 ADSs. F3 · price: Each restricted stock unit ("RSU") represents a contingent right to receive one ADS. F4 · balance_after: Reported securities are represented by 131,559 ADSs. Read SEC document |
| June 29, 2026 Filed Jun 30, 2026 20:15 UTC |
Fu WeiDirector
|
GrantRestricted Share Units · Derivative | 1,010,100 | $0.00 | $0.00 |
DisclosureSEC source: 0001885756-26-000005 · form4-06302026_040618.xml · derivative · entry 4 Fu Wei · CIK 0001885756 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 1,010,100 Underlying: Ordinary Shares · 1,010,100 shares Expires not disclosed F6 · derivative.exercise_price: Each restricted stock unit ("RSU") represents a contingent right to receive one ADS. F1 · shares: Number of underlying securities and exercise price expressed in terms of American Depositary Shares ("ADS"). F7 · derivative.exercise_date: The RSUs vest over two years in equal annual installments on June 29, 2027 and June 29, 2028. F7 · derivative.expiration_date: The RSUs vest over two years in equal annual installments on June 29, 2027 and June 29, 2028. F3 · derivative.underlying: The Ordinary Shares may be represented by ADSs. Each 10 ADSs represent 23 Ordinary Shares of the Issuer. F1 · derivative.underlying_shares: Number of underlying securities and exercise price expressed in terms of American Depositary Shares ("ADS"). F1 · balance_after: Number of underlying securities and exercise price expressed in terms of American Depositary Shares ("ADS"). Read SEC document |
| June 29, 2026 Filed Jun 30, 2026 20:15 UTC |
Fu WeiDirector
|
Grant2025 Employee Share Option (right to buy) · Derivative | 1,087,720 | $0.00 Strike: $2.45 | $0.00 |
DisclosureSEC source: 0001885756-26-000005 · form4-06302026_040618.xml · derivative · entry 3 Fu Wei · CIK 0001885756 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 1,087,720 Underlying: Ordinary Shares · 1,087,720 shares Expires 2036-06-29 F1 · derivative.exercise_price: Number of underlying securities and exercise price expressed in terms of American Depositary Shares ("ADS"). F1 · shares: Number of underlying securities and exercise price expressed in terms of American Depositary Shares ("ADS"). F5 · derivative.exercise_date: The option vests, if at all, in eight equal quarterly installments following the date on which the 30-trading-day weighted average price of the Issuer's ADS (based on trading days only) is at or above US$16.00. F3 · derivative.underlying: The Ordinary Shares may be represented by ADSs. Each 10 ADSs represent 23 Ordinary Shares of the Issuer. F1 · derivative.underlying_shares: Number of underlying securities and exercise price expressed in terms of American Depositary Shares ("ADS"). F1 · balance_after: Number of underlying securities and exercise price expressed in terms of American Depositary Shares ("ADS"). Read SEC document |
| June 29, 2026 Filed Jun 30, 2026 20:15 UTC |
Fu WeiDirector
|
Grant2025 Employee Share Option (right to buy) · Derivative | 1,087,720 | $0.00 Strike: $2.45 | $0.00 |
DisclosureSEC source: 0001885756-26-000005 · form4-06302026_040618.xml · derivative · entry 2 Fu Wei · CIK 0001885756 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 1,087,720 Underlying: Ordinary Shares · 1,087,720 shares Expires 2036-06-29 F1 · derivative.exercise_price: Number of underlying securities and exercise price expressed in terms of American Depositary Shares ("ADS"). F1 · shares: Number of underlying securities and exercise price expressed in terms of American Depositary Shares ("ADS"). F4 · derivative.exercise_date: The option vests, if at all, in eight equal quarterly installments following the date on which the 30-trading-day weighted average price of the Issuer's ADS (based on trading days only) is at or above US$12.00. F3 · derivative.underlying: The Ordinary Shares may be represented by ADSs. Each 10 ADSs represent 23 Ordinary Shares of the Issuer. F1 · derivative.underlying_shares: Number of underlying securities and exercise price expressed in terms of American Depositary Shares ("ADS"). F1 · balance_after: Number of underlying securities and exercise price expressed in terms of American Depositary Shares ("ADS"). Read SEC document |
| June 29, 2026 Filed Jun 30, 2026 20:15 UTC |
Fu WeiDirector
|
Grant2025 Employee Share Option (right to buy) · Derivative | 725,140 | $0.00 Strike: $2.45 | $0.00 |
DisclosureSEC source: 0001885756-26-000005 · form4-06302026_040618.xml · derivative · entry 1 Fu Wei · CIK 0001885756 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 725,140 Underlying: Ordinary Shares · 725,140 shares Expires 2036-06-29 F1 · derivative.exercise_price: Number of underlying securities and exercise price expressed in terms of American Depositary Shares ("ADS"). F1 · shares: Number of underlying securities and exercise price expressed in terms of American Depositary Shares ("ADS"). F2 · derivative.exercise_date: The option vests, if at all, in eight equal quarterly installments following the date on which the 30-trading-day weighted average price of the Issuer's ADS (based on trading days only) is at or above US$8.00. F3 · derivative.underlying: The Ordinary Shares may be represented by ADSs. Each 10 ADSs represent 23 Ordinary Shares of the Issuer. F1 · derivative.underlying_shares: Number of underlying securities and exercise price expressed in terms of American Depositary Shares ("ADS"). F1 · balance_after: Number of underlying securities and exercise price expressed in terms of American Depositary Shares ("ADS"). Read SEC document |
| June 22, 2026 Filed Jun 24, 2026 23:22 UTC |
Cao Sean WuxiongDirector · Chief Bus. Development Officer
|
Grant2025 Employee Share Option (right to buy) · Derivative | 181,290 | $0.00 Strike: $1.53 | $0.00 |
DisclosureSEC source: 0002109966-26-000004 · form4-06242026_110623.xml · derivative · entry 2 Cao Sean Wuxiong · CIK 0002109966 · Director · Chief Bus. Development Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 181,290 Underlying: Ordinary Shares · 181,290 shares Expires 2036-06-22 F2 · derivative.exercise_price: Number of underlying securities and exercise price expressed in terms of ADSs. F2 · shares: Number of underlying securities and exercise price expressed in terms of ADSs. F5 · derivative.exercise_date: The option vests, if at all, in eight equal quarterly installments following the date on which the 30-trading-day weighted average price of the Issuer's ADS (based on trading days only) is at or above US$8.00. F4 · derivative.underlying: The Ordinary Shares may be represented by ADSs. Each 10 ADSs represent 23 Ordinary Shares of the Issuer. F2 · derivative.underlying_shares: Number of underlying securities and exercise price expressed in terms of ADSs. F2 · balance_after: Number of underlying securities and exercise price expressed in terms of ADSs. Read SEC document |
| June 22, 2026 Filed Jun 24, 2026 23:22 UTC |
Cao Sean WuxiongDirector · Chief Bus. Development Officer
|
GrantRestricted Share Units · Derivative | 181,280 | $0.00 | $0.00 |
DisclosureSEC source: 0002109966-26-000004 · form4-06242026_110623.xml · derivative · entry 1 Cao Sean Wuxiong · CIK 0002109966 · Director · Chief Bus. Development Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 181,280 Underlying: Ordinary Shares · 181,280 shares Expires not disclosed F1 · derivative.exercise_price: Each restricted stock unit ("RSU") represents a contingent right to receive one American Depositary Shares ("ADS"). F2 · shares: Number of underlying securities and exercise price expressed in terms of ADSs. F3 · derivative.exercise_date: The RSUs shall vest over four years, with one-fourth vesting on September 3, 2026 and the balance vesting ratably over the subsequent 12 quarters on the third day of each third month. F3 · derivative.expiration_date: The RSUs shall vest over four years, with one-fourth vesting on September 3, 2026 and the balance vesting ratably over the subsequent 12 quarters on the third day of each third month. F4 · derivative.underlying: The Ordinary Shares may be represented by ADSs. Each 10 ADSs represent 23 Ordinary Shares of the Issuer. F2 · derivative.underlying_shares: Number of underlying securities and exercise price expressed in terms of ADSs. F2 · balance_after: Number of underlying securities and exercise price expressed in terms of ADSs. Read SEC document |
| June 18, 2026 Filed Jun 22, 2026 21:23 UTC |
Dennis Phillip AndrewChief Medical Officer
|
SaleOrdinary Shares | 8,494 | $0.66 | $5,606.04 |
DisclosureSEC source: 0002089237-26-000006 · form4-06222026_090646.xml · nonDerivative · entry 2 Dennis Phillip Andrew · CIK 0002089237 · Chief Medical Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 157,941 F1 · security: The Ordinary Shares may be represented by American Depositary Shares ("ADS"). Each 10 ADSs represent 23 Ordinary Shares of the Issuer. F5 · shares: Reported securities are represented by 3,693 ADSs. F6 · price: Reported sales price represents the converted sales price of the ADSs of $1.51. F7 · balance_after: Reported securities are represented by 68,670 ADSs. Read SEC document |
| June 17, 2026 Filed Jun 22, 2026 21:23 UTC |
Dennis Phillip AndrewChief Medical Officer
|
Exercise / conversionRestricted Share Units · Derivative | 10,302 | $0.00 | $0.00 |
DisclosureSEC source: 0002089237-26-000006 · form4-06222026_090646.xml · derivative · entry 3 Dennis Phillip Andrew · CIK 0002089237 · Chief Medical Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 82,422 Underlying: Ordinary Shares · 10,302 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F3 · derivative.exercise_price: Each restricted stock unit ("RSU") represents a contingent right to receive one ADS. F8 · shares: Reported securities represent ADSs. F9 · derivative.exercise_date: On June 17, 2024, the Reporting Person was granted 164,840 RSUs. The RSUs vested or shall vest over four years, with one-fourth vesting on the first anniversary of the grant date and the balance vesting ratably over the subsequent 12 quarters on the 17th day of each third month. F9 · derivative.expiration_date: On June 17, 2024, the Reporting Person was granted 164,840 RSUs. The RSUs vested or shall vest over four years, with one-fourth vesting on the first anniversary of the grant date and the balance vesting ratably over the subsequent 12 quarters on the 17th day of each third month. F1 · derivative.underlying: The Ordinary Shares may be represented by American Depositary Shares ("ADS"). Each 10 ADSs represent 23 Ordinary Shares of the Issuer. F8 · derivative.underlying_shares: Reported securities represent ADSs. F8 · balance_after: Reported securities represent ADSs. Read SEC document |
| June 17, 2026 Filed Jun 22, 2026 21:23 UTC |
Dennis Phillip AndrewChief Medical Officer
|
Exercise / conversionOrdinary Shares | 23,695 | Not disclosed | Not disclosed |
DisclosureSEC source: 0002089237-26-000006 · form4-06222026_090646.xml · nonDerivative · entry 1 Dennis Phillip Andrew · CIK 0002089237 · Chief Medical Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 166,435 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · security: The Ordinary Shares may be represented by American Depositary Shares ("ADS"). Each 10 ADSs represent 23 Ordinary Shares of the Issuer. F2 · shares: Reported securities are represented by 10,302 ADSs. F3 · price: Each restricted stock unit ("RSU") represents a contingent right to receive one ADS. F4 · balance_after: Reported securities are represented by 72,363 ADSs. Read SEC document |
| June 01, 2026 Filed Jun 2, 2026 22:46 UTC |
Xu Cong ClaireSVP, Clinical Development
|
SaleOrdinary Shares | 3,494 | $3.94 | $13,766.36 |
DisclosureSEC source: 0002114309-26-000003 · form4-06022026_100655.xml · nonDerivative · entry 2 Xu Cong Claire · CIK 0002114309 · SVP, Clinical Development 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 290,154 F1 · security: The Ordinary Shares may be represented by American Depositary Shares ("ADS"). Each 10 ADSs represent 23 Ordinary Shares of the Issuer. F5 · shares: Reported securities are represented by 1,519 ADSs. F6 · price: Reported sales price represents the converted sales price of the ADSs of $1.71. F7 · balance_after: Reported securities are represented by 126,154 ADSs. Read SEC document |
| May 30, 2026 Filed Jun 2, 2026 22:46 UTC |
Xu Cong ClaireSVP, Clinical Development
|
Exercise / conversionRestricted Share Units · Derivative | 4,079 | $0.00 | $0.00 |
DisclosureSEC source: 0002114309-26-000003 · form4-06022026_100655.xml · derivative · entry 3 Xu Cong Claire · CIK 0002114309 · SVP, Clinical Development 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 32,637 Underlying: Ordinary Shares · 4,079 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F3 · derivative.exercise_price: Each restricted stock unit ("RSU") represents a contingent right to receive one ADS. F8 · shares: Reported securities represent ADSs. F9 · derivative.exercise_date: On May 30, 2024, the Reporting Person was granted 65,270 RSUs. The RSUs vested or shall vest over four years, with one-fourth vesting on the first anniversary of the grant date and the balance vesting ratably over the subsequent 12 quarters on the 30th day of each third month. F9 · derivative.expiration_date: On May 30, 2024, the Reporting Person was granted 65,270 RSUs. The RSUs vested or shall vest over four years, with one-fourth vesting on the first anniversary of the grant date and the balance vesting ratably over the subsequent 12 quarters on the 30th day of each third month. F1 · derivative.underlying: The Ordinary Shares may be represented by American Depositary Shares ("ADS"). Each 10 ADSs represent 23 Ordinary Shares of the Issuer. F8 · derivative.underlying_shares: Reported securities represent ADSs. F8 · balance_after: Reported securities represent ADSs. Read SEC document |
| May 30, 2026 Filed Jun 2, 2026 22:46 UTC |
Xu Cong ClaireSVP, Clinical Development
|
Exercise / conversionOrdinary Shares | 9,382 | Not disclosed | Not disclosed |
DisclosureSEC source: 0002114309-26-000003 · form4-06022026_100655.xml · nonDerivative · entry 1 Xu Cong Claire · CIK 0002114309 · SVP, Clinical Development 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 293,648 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · security: The Ordinary Shares may be represented by American Depositary Shares ("ADS"). Each 10 ADSs represent 23 Ordinary Shares of the Issuer. F2 · shares: Reported securities are represented by 4,079 ADSs. F3 · price: Each restricted stock unit ("RSU") represents a contingent right to receive one ADS. F4 · balance_after: Reported securities are represented by 127,673 ADSs. Read SEC document |
| May 14, 2026 Filed May 18, 2026 20:05 UTC |
Cao Sean WuxiongDirector · See Remarks
|
SaleOrdinary Shares | 21,399 | $1.99 | $42,584.01 |
DisclosureSEC source: 0001193125-26-228889 · ownership.xml · nonDerivative · entry 1 Cao Sean Wuxiong · CIK 0002109966 · Director · See Remarks 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 35,073 F1 · security: The Ordinary Shares may be represented by American Depositary Shares ("ADS"). Each 10 ADSs represent 23 Ordinary Shares of the Issuer. F2 · kind: The reporting person sold 9,304 ADSs representing approximately 21,399 ordinary shares in connection with the partial vesting of a restricted stock unit award on January 31, 2026, solely to satisfy tax withholding obligations incurred in connection with the vesting. F3 · price: Price expressed in terms of ADSs. F4 · balance_after: The reported securities are represented by 15,249 ADSs. Read SEC document |
| April 24, 2026 Filed Apr 28, 2026 20:05 UTC |
Hagler Mark ArnoldSee Remarks
|
PurchaseOrdinary Shares | 230,000 | $2.51 | $577,300.00 |
DisclosureSEC source: 0001193125-26-186924 · ownership.xml · nonDerivative · entry 1 Hagler Mark Arnold · CIK 0002126029 · See Remarks 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 230,000 F1 · security: The Ordinary Shares may be represented by American Depositary Shares ("ADS"). Each 10 ADSs represent 23 Ordinary Shares of the Issuer. F2 · shares: The reported securities are represented by 100,000 ADSs. F3 · price: The price reported in Column 4 is a weighted average price. These ADSs were purchased in multiple transactions at prices ranging from $2.44 to $2.54, inclusive. The Reporting Person undertakes to provide the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. F2 · balance_after: The reported securities are represented by 100,000 ADSs. Read SEC document |
Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.