MIST

SEC source: 0001943112-26-000002 · form4-01282026_060107.xml · nonDerivative · entry 1

Nelson Jeffrey Edward · CIK 0001943112 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 100,000

F1 · shares: Represents a performance stock unit ("PSU") award that vested upon the certification by the Compensation Committee of the Board of Directors of the Issuer that the U.S. Food and Drug Administration has provided a New Drug Application Approval Letter granting approval of Cardamyst (etripamil).

F2 · price: Each PSU represents a contingent right to receive one common share.

SEC source: 0001771207-26-000002 · form4-01282026_060105.xml · derivative · entry 5

Muller Lorenz · CIK 0001771207 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 100,000

Underlying: Common Shares · 100,000 shares

Expires 2034-05-06

F6 · derivative.exercise_date: 50% of the option will vest on June 12, 2026 and 50% will vest on December 12, 2026, subject to the Reporting Person continuing to provide service through each such date.

SEC source: 0001771207-26-000002 · form4-01282026_060105.xml · nonDerivative · entry 1

Muller Lorenz · CIK 0001771207 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 250,052

F1 · shares: Represents a performance stock unit ("PSU") award that vested upon the certification by the Compensation Committee of the Board of Directors of the Issuer that the U.S. Food and Drug Administration has provided a New Drug Application Approval Letter granting approval of Cardamyst (etripamil).

F2 · price: Each PSU represents a contingent right to receive one common share.

SEC source: 0001787700-26-000002 · form4-01282026_060103.xml · derivative · entry 5

Hasija Amit · CIK 0001787700 · CFO & EVP of Corp. Development

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 100,000

Underlying: Common Shares · 100,000 shares

Expires 2034-05-06

F6 · derivative.exercise_date: 50% of the option will vest on June 12, 2026 and 50% will vest on December 12, 2026, subject to the Reporting Person continuing to provide service through each such date.

SEC source: 0001787700-26-000002 · form4-01282026_060103.xml · nonDerivative · entry 1

Hasija Amit · CIK 0001787700 · CFO & EVP of Corp. Development

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 150,000

F1 · shares: Represents a performance stock unit ("PSU") award that vested upon the certification by the Compensation Committee of the Board of Directors of the Issuer that the U.S. Food and Drug Administration has provided a New Drug Application Approval Letter granting approval of Cardamyst (etripamil).

F2 · price: Each PSU represents a contingent right to receive one common share.

SEC source: 0001771207-25-000002 · form4-12112025_041204.xml · nonDerivative · entry 1

Muller Lorenz · CIK 0001771207 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 150,052

F1 · kind: Represents a bona fide gift for no consideration to members of the Reporting Person's family outside the Reporting Person's household.

SEC source: 0001415889-25-019773 · form4-07152025_040715.xml · derivative · entry 3

Bharucha David · CIK 0001910985 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 53,333

Underlying: Common Shares · 53,333 shares

Expires 2030-07-11

F1 · price: The reported securities are included within 53,333 Issuer Units purchased by the Reporting Person for $1.50 per Unit. Each Unit consists of one common share, one Series A common warrant and one Series B common warrant, each warrant represents the right to purchase 53,333 shares of common stock.

F2 · derivative.exercise_date: Fully vested and exercisable.

SEC source: 0001415889-25-019773 · form4-07152025_040715.xml · derivative · entry 2

Bharucha David · CIK 0001910985 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 53,333

Underlying: Common Shares · 53,333 shares

Expires 2026-07-11

F1 · price: The reported securities are included within 53,333 Issuer Units purchased by the Reporting Person for $1.50 per Unit. Each Unit consists of one common share, one Series A common warrant and one Series B common warrant, each warrant represents the right to purchase 53,333 shares of common stock.

F2 · derivative.exercise_date: Fully vested and exercisable.

SEC source: 0001415889-25-019773 · form4-07152025_040715.xml · nonDerivative · entry 1

Bharucha David · CIK 0001910985 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 63,333

F1 · price: The reported securities are included within 53,333 Issuer Units purchased by the Reporting Person for $1.50 per Unit. Each Unit consists of one common share, one Series A common warrant and one Series B common warrant, each warrant represents the right to purchase 53,333 shares of common stock.

SEC source: 0001415889-25-019772 · form4-07152025_040710.xml · derivative · entry 3

Oliveto Joseph · CIK 0001437782 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 66,666

Underlying: Common Shares · 66,666 shares

Expires 2030-07-11

F1 · price: The reported securities are included within 66,666 Issuer Units purchased by the Reporting Person for $1.50 per Unit. Each Unit consists of one common share, one Series A common warrant and one Series B common warrant, each warrant represents the right to purchase 66,666 shares of common stock.

F2 · derivative.exercise_date: Fully vested and exercisable.

SEC source: 0001415889-25-019772 · form4-07152025_040710.xml · derivative · entry 2

Oliveto Joseph · CIK 0001437782 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 66,666

Underlying: Common Shares · 66,666 shares

Expires 2026-07-11

F1 · price: The reported securities are included within 66,666 Issuer Units purchased by the Reporting Person for $1.50 per Unit. Each Unit consists of one common share, one Series A common warrant and one Series B common warrant, each warrant represents the right to purchase 66,666 shares of common stock.

F2 · derivative.exercise_date: Fully vested and exercisable.

SEC source: 0001415889-25-019772 · form4-07152025_040710.xml · nonDerivative · entry 1

Oliveto Joseph · CIK 0001437782 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 347,221

F1 · price: The reported securities are included within 66,666 Issuer Units purchased by the Reporting Person for $1.50 per Unit. Each Unit consists of one common share, one Series A common warrant and one Series B common warrant, each warrant represents the right to purchase 66,666 shares of common stock.

SEC source: 0001415889-25-019770 · form4-07152025_040701.xml · derivative · entry 3

PAPA JOSEPH C · CIK 0001242215 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 100,000

Underlying: Common Shares · 100,000 shares

Expires 2030-07-11

F1 · price: The reported securities are included within 100,000 Issuer Units purchased by the Reporting Person for $1.50 per Unit. Each Unit consists of one common share, one Series A common warrant and one Series B common warrant, each warrant represents the right to purchase 100,000 shares of common stock.

F2 · derivative.exercise_date: Fully vested and exercisable.

SEC source: 0001415889-25-019770 · form4-07152025_040701.xml · derivative · entry 2

PAPA JOSEPH C · CIK 0001242215 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 100,000

Underlying: Common Shares · 100,000 shares

Expires 2026-07-11

F1 · price: The reported securities are included within 100,000 Issuer Units purchased by the Reporting Person for $1.50 per Unit. Each Unit consists of one common share, one Series A common warrant and one Series B common warrant, each warrant represents the right to purchase 100,000 shares of common stock.

F2 · derivative.exercise_date: Fully vested and exercisable.

SEC source: 0001415889-25-019770 · form4-07152025_040701.xml · nonDerivative · entry 1

PAPA JOSEPH C · CIK 0001242215 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 100,000

F1 · price: The reported securities are included within 100,000 Issuer Units purchased by the Reporting Person for $1.50 per Unit. Each Unit consists of one common share, one Series A common warrant and one Series B common warrant, each warrant represents the right to purchase 100,000 shares of common stock.

SEC source: 0001415889-25-019775 · form4-07152025_040722.xml · derivative · entry 3

Hasija Amit · CIK 0001787700 · CFO & EVP of Corp. Development

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 50,000

Underlying: Common Shares · 50,000 shares

Expires 2030-07-11

F1 · price: The reported securities are included within 50,000 Issuer Units purchased by the Reporting Person for $1.50 per Unit. Each Unit consists of one common share, one Series A common warrant and one Series B common warrant, each warrant represents the right to purchase 50,000 shares of common stock.

F2 · derivative.exercise_date: Fully vested and exercisable.

SEC source: 0001415889-25-019775 · form4-07152025_040722.xml · derivative · entry 2

Hasija Amit · CIK 0001787700 · CFO & EVP of Corp. Development

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 50,000

Underlying: Common Shares · 50,000 shares

Expires 2026-07-11

F1 · price: The reported securities are included within 50,000 Issuer Units purchased by the Reporting Person for $1.50 per Unit. Each Unit consists of one common share, one Series A common warrant and one Series B common warrant, each warrant represents the right to purchase 50,000 shares of common stock.

F2 · derivative.exercise_date: Fully vested and exercisable.

SEC source: 0001415889-25-019775 · form4-07152025_040722.xml · nonDerivative · entry 1

Hasija Amit · CIK 0001787700 · CFO & EVP of Corp. Development

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 50,000

F1 · price: The reported securities are included within 50,000 Issuer Units purchased by the Reporting Person for $1.50 per Unit. Each Unit consists of one common share, one Series A common warrant and one Series B common warrant, each warrant represents the right to purchase 50,000 shares of common stock.

SEC source: 0001415889-25-019776 · form4-07152025_040723.xml · derivative · entry 5

Liebert Debra K. · CIK 0001772891 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,793

Underlying: Common Shares · 16,793 shares

Expires 2030-07-11

F1 · price: The reported securities are included within 16,793 Issuer Units purchased by the Reporting Person for $1.50 per Unit. Each Unit consists of one common share, one Series A common warrant and one Series B common warrant, each warrant represents the right to purchase 16,793 shares of common stock.

F3 · derivative.exercise_date: Fully vested and exercisable.

SEC source: 0001415889-25-019776 · form4-07152025_040723.xml · derivative · entry 4

Liebert Debra K. · CIK 0001772891 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,793

Underlying: Common Shares · 16,793 shares

Expires 2026-07-11

F1 · price: The reported securities are included within 16,793 Issuer Units purchased by the Reporting Person for $1.50 per Unit. Each Unit consists of one common share, one Series A common warrant and one Series B common warrant, each warrant represents the right to purchase 16,793 shares of common stock.

F3 · derivative.exercise_date: Fully vested and exercisable.

SEC source: 0001415889-25-019776 · form4-07152025_040723.xml · nonDerivative · entry 1

Liebert Debra K. · CIK 0001772891 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,793

F1 · price: The reported securities are included within 16,793 Issuer Units purchased by the Reporting Person for $1.50 per Unit. Each Unit consists of one common share, one Series A common warrant and one Series B common warrant, each warrant represents the right to purchase 16,793 shares of common stock.

SEC source: 0001415889-25-019774 · form4-07152025_040719.xml · derivative · entry 3

Wills Robert James · CIK 0001634189 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 50,000

Underlying: Common Shares · 50,000 shares

Expires 2030-07-11

F1 · price: The reported securities are included within 50,000 Issuer Units purchased by the Reporting Person for $1.50 per Unit. Each Unit consists of one common share, one Series A common warrant and one Series B common warrant, each warrant represents the right to purchase 50,000 shares of common stock.

F2 · derivative.exercise_date: Fully vested and exercisable.

SEC source: 0001415889-25-019774 · form4-07152025_040719.xml · derivative · entry 2

Wills Robert James · CIK 0001634189 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 50,000

Underlying: Common Shares · 50,000 shares

Expires 2026-07-11

F1 · price: The reported securities are included within 50,000 Issuer Units purchased by the Reporting Person for $1.50 per Unit. Each Unit consists of one common share, one Series A common warrant and one Series B common warrant, each warrant represents the right to purchase 50,000 shares of common stock.

F2 · derivative.exercise_date: Fully vested and exercisable.

SEC source: 0001415889-25-019774 · form4-07152025_040719.xml · nonDerivative · entry 1

Wills Robert James · CIK 0001634189 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 65,000

F1 · price: The reported securities are included within 50,000 Issuer Units purchased by the Reporting Person for $1.50 per Unit. Each Unit consists of one common share, one Series A common warrant and one Series B common warrant, each warrant represents the right to purchase 50,000 shares of common stock.

SEC source: 0001415889-25-019771 · form4-07152025_040705.xml · derivative · entry 3

Muller Lorenz · CIK 0001771207 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 66,666

Underlying: Common Shares · 66,666 shares

Expires 2030-07-11

F1 · price: The reported securities are included within 66,666 Issuer Units purchased by the Reporting Person for $1.50 per Unit. Each Unit consists of one common share, one Series A common warrant and one Series B common warrant, each warrant represents the right to purchase 66,666 shares of common stock.

F2 · derivative.exercise_date: Fully vested and exercisable.

SEC source: 0001415889-25-019771 · form4-07152025_040705.xml · derivative · entry 2

Muller Lorenz · CIK 0001771207 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 66,666

Underlying: Common Shares · 66,666 shares

Expires 2026-07-11

F1 · price: The reported securities are included within 66,666 Issuer Units purchased by the Reporting Person for $1.50 per Unit. Each Unit consists of one common share, one Series A common warrant and one Series B common warrant, each warrant represents the right to purchase 66,666 shares of common stock.

F2 · derivative.exercise_date: Fully vested and exercisable.

SEC source: 0001415889-25-019771 · form4-07152025_040705.xml · nonDerivative · entry 1

Muller Lorenz · CIK 0001771207 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 175,052

F1 · price: The reported securities are included within 66,666 Issuer Units purchased by the Reporting Person for $1.50 per Unit. Each Unit consists of one common share, one Series A common warrant and one Series B common warrant, each warrant represents the right to purchase 66,666 shares of common stock.

SEC source: 0001415889-25-016932 · form4-06122025_040611.xml · derivative · entry 1

PAPA JOSEPH C · CIK 0001242215 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 40,000

Underlying: Common Stock · 40,000 shares

Expires 2035-06-10

F1 · derivative.exercise_date: This option will vest in twelve (12) equal monthly installments, beginning on July 10, 2025, provided that the option will in any case be fully vested on the date of next annual meeting of the stockholders of the Issuer, subject to the Reporting Person continuing to provide service through each such vesting date.

SEC source: 0001415889-25-016931 · form4-06122025_040608.xml · derivative · entry 1

Giles Lisa M. · CIK 0001568850 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 40,000

Underlying: Common Stock · 40,000 shares

Expires 2035-06-10

F1 · derivative.exercise_date: This option will vest in twelve (12) equal monthly installments, beginning on July 10, 2025, provided that the option will in any case be fully vested on the date of next annual meeting of the stockholders of the Issuer, subject to the Reporting Person continuing to provide service through each such vesting date.

SEC source: 0001415889-25-016933 · form4-06122025_040612.xml · derivative · entry 1

Saik Andrew · CIK 0001616284 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 40,000

Underlying: Common Stock · 40,000 shares

Expires 2035-06-10

F1 · derivative.exercise_date: This option will vest in twelve (12) equal monthly installments, beginning on July 10, 2025, provided that the option will in any case be fully vested on the date of next annual meeting of the stockholders of the Issuer, subject to the Reporting Person continuing to provide service through each such vesting date.

SEC source: 0001415889-25-016930 · form4-06122025_040605.xml · derivative · entry 1

Fischer Seth H. Z. · CIK 0001573553 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 40,000

Underlying: Common Stock · 40,000 shares

Expires 2035-06-10

F1 · derivative.exercise_date: This option will vest in twelve (12) equal monthly installments, beginning on July 10, 2025, provided that the option will in any case be fully vested on the date of next annual meeting of the stockholders of the Issuer, subject to the Reporting Person continuing to provide service through each such vesting date.

SEC source: 0001415889-25-016935 · form4-06122025_040616.xml · derivative · entry 1

Wills Robert James · CIK 0001634189 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 40,000

Underlying: Common Stock · 40,000 shares

Expires 2035-06-10

F1 · derivative.exercise_date: This option will vest in twelve (12) equal monthly installments, beginning on July 10, 2025, provided that the option will in any case be fully vested on the date of next annual meeting of the stockholders of the Issuer, subject to the Reporting Person continuing to provide service through each such vesting date.

SEC source: 0001415889-25-016934 · form4-06122025_040614.xml · derivative · entry 1

TOMSICEK MICHAEL JOHN · CIK 0001570392 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 40,000

Underlying: Common Stock · 40,000 shares

Expires 2035-06-10

F1 · derivative.exercise_date: This option will vest in twelve (12) equal monthly installments, beginning on July 10, 2025, provided that the option will in any case be fully vested on the date of next annual meeting of the stockholders of the Issuer, subject to the Reporting Person continuing to provide service through each such vesting date.

SEC source: 0001415889-25-016929 · form4-06122025_040603.xml · derivative · entry 1

Duty Stuart · CIK 0001970274 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 40,000

Underlying: Common Stock · 40,000 shares

Expires 2035-06-10

F1 · derivative.exercise_date: This option will vest in twelve (12) equal monthly installments, beginning on July 10, 2025, provided that the option will in any case be fully vested on the date of next annual meeting of the stockholders of the Issuer, subject to the Reporting Person continuing to provide service through each such vesting date.

SEC source: 0001415889-25-002266 · form4-01292025_040106.xml · derivative · entry 2

Bharucha David · CIK 0001910985 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 80,400

Underlying: Common Shares · 80,400 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one common share.

F3 · derivative.exercise_date: One-fourth (1/4th) of the shares subject to the restricted stock unit award vest on each of Jaunary 27, 2026, Jaunary 27, 2027, Jaunary 27, 2028 and Jaunary 27, 2029, subject to the Reporting Person continuing to provide service through each such date.

F3 · derivative.expiration_date: One-fourth (1/4th) of the shares subject to the restricted stock unit award vest on each of Jaunary 27, 2026, Jaunary 27, 2027, Jaunary 27, 2028 and Jaunary 27, 2029, subject to the Reporting Person continuing to provide service through each such date.

SEC source: 0001415889-25-002266 · form4-01292025_040106.xml · derivative · entry 1

Bharucha David · CIK 0001910985 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 120,600

Underlying: Common Shares · 120,600 shares

Expires 2035-01-27

F1 · derivative.exercise_date: One-fourth (1/4th) of the shares subject to the option vest on Jaunary 27, 2026, and one thirty-sixth (1/36th) of the remaining shares subject to this option shall vest each month thereafter, subject to the Reporting Person continuing to provide service through each such date.

SEC source: 0001415889-25-002265 · form4-01292025_040104.xml · derivative · entry 2

Oliveto Joseph · CIK 0001437782 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 266,400

Underlying: Common Shares · 266,400 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one common share.

F3 · derivative.exercise_date: One-fourth (1/4th) of the shares subject to the restricted stock unit award vest on each of Jaunary 27, 2026, Jaunary 27, 2027, Jaunary 27, 2028 and Jaunary 27, 2029, subject to the Reporting Person continuing to provide service through each such date.

F3 · derivative.expiration_date: One-fourth (1/4th) of the shares subject to the restricted stock unit award vest on each of Jaunary 27, 2026, Jaunary 27, 2027, Jaunary 27, 2028 and Jaunary 27, 2029, subject to the Reporting Person continuing to provide service through each such date.

SEC source: 0001415889-25-002265 · form4-01292025_040104.xml · derivative · entry 1

Oliveto Joseph · CIK 0001437782 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 399,600

Underlying: Common Shares · 399,600 shares

Expires 2035-01-27

F1 · derivative.exercise_date: One-fourth (1/4th) of the shares subject to the option vest on Jaunary 27, 2026, and one thirty-sixth (1/36th) of the remaining shares subject to this option shall vest each month thereafter, subject to the Reporting Person continuing to provide service through each such date.

SEC source: 0001415889-25-002269 · form4-01292025_040113.xml · derivative · entry 2

Nelson Jeffrey Edward · CIK 0001943112 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 80,400

Underlying: Common Shares · 80,400 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one common share.

F3 · derivative.exercise_date: One-fourth (1/4th) of the shares subject to the restricted stock unit award vest on each of Jaunary 27, 2026, Jaunary 27, 2027, Jaunary 27, 2028 and Jaunary 27, 2029, subject to the Reporting Person continuing to provide service through each such date.

F3 · derivative.expiration_date: One-fourth (1/4th) of the shares subject to the restricted stock unit award vest on each of Jaunary 27, 2026, Jaunary 27, 2027, Jaunary 27, 2028 and Jaunary 27, 2029, subject to the Reporting Person continuing to provide service through each such date.

SEC source: 0001415889-25-002269 · form4-01292025_040113.xml · derivative · entry 1

Nelson Jeffrey Edward · CIK 0001943112 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 120,600

Underlying: Common Shares · 120,600 shares

Expires 2035-01-27

F1 · derivative.exercise_date: One-fourth (1/4th) of the shares subject to the option vest on Jaunary 27, 2026, and one thirty-sixth (1/36th) of the remaining shares subject to this option shall vest each month thereafter, subject to the Reporting Person continuing to provide service through each such date.

SEC source: 0001415889-25-002267 · form4-01292025_040108.xml · derivative · entry 2

Hasija Amit · CIK 0001787700 · CFO & EVP of Corp. Development

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 80,400

Underlying: Common Shares · 80,400 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one common share.

F3 · derivative.exercise_date: One-fourth (1/4th) of the shares subject to the restricted stock unit award vest on each of Jaunary 27, 2026, Jaunary 27, 2027, Jaunary 27, 2028 and Jaunary 27, 2029, subject to the Reporting Person continuing to provide service through each such date.

F3 · derivative.expiration_date: One-fourth (1/4th) of the shares subject to the restricted stock unit award vest on each of Jaunary 27, 2026, Jaunary 27, 2027, Jaunary 27, 2028 and Jaunary 27, 2029, subject to the Reporting Person continuing to provide service through each such date.

SEC source: 0001415889-25-002267 · form4-01292025_040108.xml · derivative · entry 1

Hasija Amit · CIK 0001787700 · CFO & EVP of Corp. Development

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 120,600

Underlying: Common Shares · 120,600 shares

Expires 2035-01-27

F1 · derivative.exercise_date: One-fourth (1/4th) of the shares subject to the option vest on Jaunary 27, 2026, and one thirty-sixth (1/36th) of the remaining shares subject to this option shall vest each month thereafter, subject to the Reporting Person continuing to provide service through each such date.

SEC source: 0001415889-25-002268 · form4-01292025_040111.xml · derivative · entry 2

Muller Lorenz · CIK 0001771207 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 80,400

Underlying: Common Shares · 80,400 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one common share.

F3 · derivative.exercise_date: One-fourth (1/4th) of the shares subject to the restricted stock unit award vest on each of Jaunary 27, 2026, Jaunary 27, 2027, Jaunary 27, 2028 and Jaunary 27, 2029, subject to the Reporting Person continuing to provide service through each such date.

F3 · derivative.expiration_date: One-fourth (1/4th) of the shares subject to the restricted stock unit award vest on each of Jaunary 27, 2026, Jaunary 27, 2027, Jaunary 27, 2028 and Jaunary 27, 2029, subject to the Reporting Person continuing to provide service through each such date.

SEC source: 0001415889-25-002268 · form4-01292025_040111.xml · derivative · entry 1

Muller Lorenz · CIK 0001771207 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 120,600

Underlying: Common Shares · 120,600 shares

Expires 2035-01-27

F1 · derivative.exercise_date: One-fourth (1/4th) of the shares subject to the option vest on Jaunary 27, 2026, and one thirty-sixth (1/36th) of the remaining shares subject to this option shall vest each month thereafter, subject to the Reporting Person continuing to provide service through each such date.

SEC source: 0001415889-24-022914 · form4-09052024_080906.xml · derivative · entry 1

PAPA JOSEPH C · CIK 0001242215 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 80,000

Underlying: Common Shares · 80,000 shares

Expires 2034-09-03

F1 · derivative.exercise_date: This option will vest in equal monthly installments, beginning on October 3, 2024, over a period of three years, subject to the Reporting Person continuing to provide service through each such vesting date.

SEC source: 0001415889-24-022537 · form4-08292024_040813.xml · derivative · entry 1

Saik Andrew · CIK 0001616284 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 40,000

Underlying: Common Shares · 40,000 shares

Expires 2034-08-28

F1 · derivative.exercise_date: This option will vest in twelve (12) equal monthly installments, beginning on September 28, 2024, provided that the option will in any case be fully vested on the date of next annual meeting of the stockholders of the Issuer, subject to the Reporting Person continuing to provide service through each such vesting date.

SEC source: 0001415889-24-022536 · form4-08292024_040810.xml · derivative · entry 1

Duty Stuart · CIK 0001970274 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 40,000

Underlying: Common Shares · 40,000 shares

Expires 2034-08-28

F1 · derivative.exercise_date: This option will vest in twelve (12) equal monthly installments, beginning on September 28, 2024, provided that the option will in any case be fully vested on the date of next annual meeting of the stockholders of the Issuer, subject to the Reporting Person continuing to provide service through each such vesting date.

SEC source: 0001415889-24-022534 · form4-08292024_040806.xml · derivative · entry 1

Giles Lisa M. · CIK 0001568850 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 40,000

Underlying: Common Shares · 40,000 shares

Expires 2034-08-28

F1 · derivative.exercise_date: This option will vest in twelve (12) equal monthly installments, beginning on September 28, 2024, provided that the option will in any case be fully vested on the date of next annual meeting of the stockholders of the Issuer, subject to the Reporting Person continuing to provide service through each such vesting date.

SEC source: 0001415889-24-022533 · form4-08292024_040804.xml · derivative · entry 1

Fischer Seth H. Z. · CIK 0001573553 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 40,000

Underlying: Common Shares · 40,000 shares

Expires 2034-08-28

F1 · derivative.exercise_date: This option will vest in twelve (12) equal monthly installments, beginning on September 28, 2024, provided that the option will in any case be fully vested on the date of next annual meeting of the stockholders of the Issuer, subject to the Reporting Person continuing to provide service through each such vesting date.

SEC source: 0001415889-24-022535 · form4-08292024_040808.xml · derivative · entry 1

TOMSICEK MICHAEL JOHN · CIK 0001570392 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 40,000

Underlying: Common Shares · 40,000 shares

Expires 2034-08-28

F1 · derivative.exercise_date: This option will vest in twelve (12) equal monthly installments, beginning on September 28, 2024, provided that the option will in any case be fully vested on the date of next annual meeting of the stockholders of the Issuer, subject to the Reporting Person continuing to provide service through each such vesting date.