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Nasdaq · USD

KPTI

Karyopharm Therapeutics Inc.

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Tapewire entity
781
SEC CIK
0001503802
Parsed reports
479

Last 12 months

Inside the activity.

0 purchase rows · 20 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202500
Dec 202500
Jan 202602
Feb 202602
Mar 202606
Apr 202601
May 202606
Jun 202600
Jul 202601
Aug 202600
Sep 202601
Oct 202601

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
December 06, 2019 Filed Dec 10, 2019 22:18 UTC
Primiano Christopher BrettEVP, CBO, GC & Secretary
Exercise / conversionCommon Stock 5,000 $6.54 $32,700.00
Disclosure

SEC source: 0001209191-19-059914 · doc4.xml · nonDerivative · entry 1

Primiano Christopher Brett · CIK 0001603510 · EVP, CBO, GC & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,653

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · balance_after: Includes 3,772 shares acquired under the Karyopharm Therapeutics Inc. 2013 Employee Stock Purchase Plan.

Read SEC document
November 11, 2019 Filed Nov 12, 2019 21:39 UTC
Kauffman MichaelDirector · Chief Executive Officer
Exercise / conversionStock Option (right to buy) · Derivative 10,000 $0.00 Strike: $4.75 $0.00
Disclosure

SEC source: 0001209191-19-056041 · doc4.xml · derivative · entry 7

Kauffman Michael · CIK 0001364719 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 406,061

Underlying: Common Stock · 10,000 shares

Expires 2023-09-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F7 · derivative.exercise_date: This option, representing a right to purchase a specified number of shares, vested as to 25% of the shares on September 3, 2014, and the remaining 75% vested in 36 equal monthly installments thereafter.

Read SEC document
November 11, 2019 Filed Nov 12, 2019 21:39 UTC
Kauffman MichaelDirector · Chief Executive Officer
SaleCommon Stock 10,000 $14.76 $147,610.00
Disclosure

SEC source: 0001209191-19-056041 · doc4.xml · nonDerivative · entry 2

Kauffman Michael · CIK 0001364719 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 529,767

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · price: Represents the weighted average sale price. These shares were sold in multiple transactions at prices ranging from $14.65 to $14.835, inclusive. The reporting person undertakes to provide upon request by the U.S. Securities and Exchange Commission staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price.

Read SEC document
November 11, 2019 Filed Nov 12, 2019 21:39 UTC
Kauffman MichaelDirector · Chief Executive Officer
Exercise / conversionCommon Stock 10,000 $4.75 $47,520.00
Disclosure

SEC source: 0001209191-19-056041 · doc4.xml · nonDerivative · entry 1

Kauffman Michael · CIK 0001364719 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 539,767

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document
November 11, 2019 Filed Nov 12, 2019 21:34 UTC
Shacham SharonPresident & CSO
Exercise / conversionStock Option (right to buy) · Derivative 10,000 $0.00 Strike: $4.75 $0.00
Disclosure

SEC source: 0001209191-19-056027 · doc4.xml · derivative · entry 8

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 406,061

Underlying: Common Stock · 10,000 shares

Expires 2023-09-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the spouse of the reporting person.

F7 · derivative.exercise_date: This option, representing a right to purchase a specified number of shares, vested as to 25% of the shares on September 3, 2014, and the remaining 75% vested in 36 equal monthly installments thereafter.

Read SEC document
November 11, 2019 Filed Nov 12, 2019 21:34 UTC
Shacham SharonPresident & CSO
SaleCommon Stock 10,000 $14.76 $147,610.00
Disclosure

SEC source: 0001209191-19-056027 · doc4.xml · nonDerivative · entry 4

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 529,767

F3 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the spouse of the reporting person.

F4 · price: Represents the weighted average sale price. These shares were sold in multiple transactions at prices ranging from $14.65 to $14.835, inclusive. The spouse of the reporting person undertakes to provide upon request by the U.S. Securities and Exchange Commission staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price.

Read SEC document
November 11, 2019 Filed Nov 12, 2019 21:34 UTC
Shacham SharonPresident & CSO
Exercise / conversionCommon Stock 10,000 $4.75 $47,520.00
Disclosure

SEC source: 0001209191-19-056027 · doc4.xml · nonDerivative · entry 3

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 539,767

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the spouse of the reporting person.

Read SEC document
November 08, 2019 Filed Nov 12, 2019 21:39 UTC
Kauffman MichaelDirector · Chief Executive Officer
Exercise / conversionStock Option (right to buy) · Derivative 10,000 $0.00 Strike: $4.75 $0.00
Disclosure

SEC source: 0001209191-19-056041 · doc4.xml · derivative · entry 8

Kauffman Michael · CIK 0001364719 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 450,303

Underlying: Common Stock · 10,000 shares

Expires 2023-09-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the spouse of the reporting person.

F7 · derivative.exercise_date: This option, representing a right to purchase a specified number of shares, vested as to 25% of the shares on September 3, 2014, and the remaining 75% vested in 36 equal monthly installments thereafter.

Read SEC document
November 08, 2019 Filed Nov 12, 2019 21:39 UTC
Kauffman MichaelDirector · Chief Executive Officer
SaleCommon Stock 10,000 $14.63 $146,254.00
Disclosure

SEC source: 0001209191-19-056041 · doc4.xml · nonDerivative · entry 4

Kauffman Michael · CIK 0001364719 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 731,134

F3 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the spouse of the reporting person.

F4 · price: Represents the weighted average sale price. These shares were sold in multiple transactions at prices ranging from $14.22 to $14.90, inclusive. The spouse of the reporting person undertakes to provide upon request by the U.S. Securities and Exchange Commission staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price.

Read SEC document
November 08, 2019 Filed Nov 12, 2019 21:39 UTC
Kauffman MichaelDirector · Chief Executive Officer
Exercise / conversionCommon Stock 10,000 $4.75 $47,520.00
Disclosure

SEC source: 0001209191-19-056041 · doc4.xml · nonDerivative · entry 3

Kauffman Michael · CIK 0001364719 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 741,134

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the spouse of the reporting person.

Read SEC document
November 08, 2019 Filed Nov 12, 2019 21:34 UTC
Shacham SharonPresident & CSO
Exercise / conversionStock Option (right to buy) · Derivative 10,000 $0.00 Strike: $4.75 $0.00
Disclosure

SEC source: 0001209191-19-056027 · doc4.xml · derivative · entry 7

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 450,303

Underlying: Common Stock · 10,000 shares

Expires 2023-09-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F7 · derivative.exercise_date: This option, representing a right to purchase a specified number of shares, vested as to 25% of the shares on September 3, 2014, and the remaining 75% vested in 36 equal monthly installments thereafter.

Read SEC document
November 08, 2019 Filed Nov 12, 2019 21:34 UTC
Shacham SharonPresident & CSO
SaleCommon Stock 10,000 $14.63 $146,254.00
Disclosure

SEC source: 0001209191-19-056027 · doc4.xml · nonDerivative · entry 2

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 731,134

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · price: Represents the weighted average sale price. These shares were sold in multiple transactions at prices ranging from $14.22 to $14.90, inclusive. The reporting person undertakes to provide upon request by the U.S. Securities and Exchange Commission staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price.

Read SEC document
November 08, 2019 Filed Nov 12, 2019 21:34 UTC
Shacham SharonPresident & CSO
Exercise / conversionCommon Stock 10,000 $4.75 $47,520.00
Disclosure

SEC source: 0001209191-19-056027 · doc4.xml · nonDerivative · entry 1

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 741,134

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document
November 01, 2019 Filed Nov 5, 2019 21:10 UTC
Shacham SharonPresident & CSO
Exercise / conversionStock Option (right to buy) · Derivative 10,000 $0.00 Strike: $4.75 $0.00
Disclosure

SEC source: 0001209191-19-055170 · doc4.xml · derivative · entry 8

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 416,061

Underlying: Common Stock · 10,000 shares

Expires 2023-09-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the spouse of the reporting person.

F5 · derivative.exercise_date: This option, representing a right to purchase a specified number of shares, vested as to 25% of the shares on September 3, 2014, and the remaining 75% vested in 36 equal monthly installments thereafter.

Read SEC document
November 01, 2019 Filed Nov 5, 2019 21:10 UTC
Shacham SharonPresident & CSO
Exercise / conversionStock Option (right to buy) · Derivative 10,000 $0.00 Strike: $4.75 $0.00
Disclosure

SEC source: 0001209191-19-055170 · doc4.xml · derivative · entry 7

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 460,303

Underlying: Common Stock · 10,000 shares

Expires 2023-09-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F5 · derivative.exercise_date: This option, representing a right to purchase a specified number of shares, vested as to 25% of the shares on September 3, 2014, and the remaining 75% vested in 36 equal monthly installments thereafter.

Read SEC document
November 01, 2019 Filed Nov 5, 2019 21:10 UTC
Shacham SharonPresident & CSO
SaleCommon Stock 10,000 $12.00 $120,000.00
Disclosure

SEC source: 0001209191-19-055170 · doc4.xml · nonDerivative · entry 4

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 529,767

F2 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the spouse of the reporting person.

Read SEC document
November 01, 2019 Filed Nov 5, 2019 21:10 UTC
Shacham SharonPresident & CSO
Exercise / conversionCommon Stock 10,000 $4.75 $47,520.00
Disclosure

SEC source: 0001209191-19-055170 · doc4.xml · nonDerivative · entry 3

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 539,767

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the spouse of the reporting person.

Read SEC document
November 01, 2019 Filed Nov 5, 2019 21:10 UTC
Shacham SharonPresident & CSO
SaleCommon Stock 10,000 $12.00 $120,000.00
Disclosure

SEC source: 0001209191-19-055170 · doc4.xml · nonDerivative · entry 2

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 731,134

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document
November 01, 2019 Filed Nov 5, 2019 21:10 UTC
Shacham SharonPresident & CSO
Exercise / conversionCommon Stock 10,000 $4.75 $47,520.00
Disclosure

SEC source: 0001209191-19-055170 · doc4.xml · nonDerivative · entry 1

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 741,134

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document
November 01, 2019 Filed Nov 5, 2019 21:08 UTC
Kauffman MichaelDirector · Chief Executive Officer
Exercise / conversionStock Option (right to buy) · Derivative 10,000 $0.00 Strike: $4.75 $0.00
Disclosure

SEC source: 0001209191-19-055167 · doc4.xml · derivative · entry 8

Kauffman Michael · CIK 0001364719 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 460,303

Underlying: Common Stock · 10,000 shares

Expires 2023-09-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the spouse of the reporting person.

F5 · derivative.exercise_date: This option, representing a right to purchase a specified number of shares, vested as to 25% of the shares on September 3, 2014, and the remaining 75% vested in 36 equal monthly installments thereafter.

Read SEC document
November 01, 2019 Filed Nov 5, 2019 21:08 UTC
Kauffman MichaelDirector · Chief Executive Officer
Exercise / conversionStock Option (right to buy) · Derivative 10,000 $0.00 Strike: $4.75 $0.00
Disclosure

SEC source: 0001209191-19-055167 · doc4.xml · derivative · entry 7

Kauffman Michael · CIK 0001364719 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 416,061

Underlying: Common Stock · 10,000 shares

Expires 2023-09-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F5 · derivative.exercise_date: This option, representing a right to purchase a specified number of shares, vested as to 25% of the shares on September 3, 2014, and the remaining 75% vested in 36 equal monthly installments thereafter.

Read SEC document
November 01, 2019 Filed Nov 5, 2019 21:08 UTC
Kauffman MichaelDirector · Chief Executive Officer
SaleCommon Stock 10,000 $12.00 $120,000.00
Disclosure

SEC source: 0001209191-19-055167 · doc4.xml · nonDerivative · entry 4

Kauffman Michael · CIK 0001364719 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 731,134

F2 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the spouse of the reporting person.

Read SEC document
November 01, 2019 Filed Nov 5, 2019 21:08 UTC
Kauffman MichaelDirector · Chief Executive Officer
Exercise / conversionCommon Stock 10,000 $4.75 $47,520.00
Disclosure

SEC source: 0001209191-19-055167 · doc4.xml · nonDerivative · entry 3

Kauffman Michael · CIK 0001364719 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 741,134

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the spouse of the reporting person.

Read SEC document
November 01, 2019 Filed Nov 5, 2019 21:08 UTC
Kauffman MichaelDirector · Chief Executive Officer
SaleCommon Stock 10,000 $12.00 $120,000.00
Disclosure

SEC source: 0001209191-19-055167 · doc4.xml · nonDerivative · entry 2

Kauffman Michael · CIK 0001364719 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 529,767

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document
November 01, 2019 Filed Nov 5, 2019 21:08 UTC
Kauffman MichaelDirector · Chief Executive Officer
Exercise / conversionCommon Stock 10,000 $4.75 $47,520.00
Disclosure

SEC source: 0001209191-19-055167 · doc4.xml · nonDerivative · entry 1

Kauffman Michael · CIK 0001364719 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 539,767

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document
September 16, 2019 Filed Sep 17, 2019 20:56 UTC
Kauffman MichaelDirector · Chief Executive Officer
Exercise / conversionStock Option (right to buy) · Derivative 10,000 $0.00 Strike: $4.75 $0.00
Disclosure

SEC source: 0001209191-19-049870 · doc4.xml · derivative · entry 8

Kauffman Michael · CIK 0001364719 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 470,303

Underlying: Common Stock · 10,000 shares

Expires 2023-09-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the spouse of the reporting person.

F5 · derivative.exercise_date: This option, representing a right to purchase a specified number of shares, vested as to 25% of the shares on September 3, 2014, and the remaining 75% vested in 36 equal monthly installments thereafter.

Read SEC document
September 16, 2019 Filed Sep 17, 2019 20:56 UTC
Kauffman MichaelDirector · Chief Executive Officer
Exercise / conversionStock Option (right to buy) · Derivative 10,000 $0.00 Strike: $4.75 $0.00
Disclosure

SEC source: 0001209191-19-049870 · doc4.xml · derivative · entry 7

Kauffman Michael · CIK 0001364719 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 426,061

Underlying: Common Stock · 10,000 shares

Expires 2023-09-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F5 · derivative.exercise_date: This option, representing a right to purchase a specified number of shares, vested as to 25% of the shares on September 3, 2014, and the remaining 75% vested in 36 equal monthly installments thereafter.

Read SEC document
September 16, 2019 Filed Sep 17, 2019 20:56 UTC
Kauffman MichaelDirector · Chief Executive Officer
SaleCommon Stock 10,000 $12.00 $120,000.00
Disclosure

SEC source: 0001209191-19-049870 · doc4.xml · nonDerivative · entry 4

Kauffman Michael · CIK 0001364719 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 731,134

F2 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the spouse of the reporting person.

Read SEC document
September 16, 2019 Filed Sep 17, 2019 20:56 UTC
Kauffman MichaelDirector · Chief Executive Officer
Exercise / conversionCommon Stock 10,000 $4.75 $47,520.00
Disclosure

SEC source: 0001209191-19-049870 · doc4.xml · nonDerivative · entry 3

Kauffman Michael · CIK 0001364719 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 741,134

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the spouse of the reporting person.

Read SEC document
September 16, 2019 Filed Sep 17, 2019 20:56 UTC
Kauffman MichaelDirector · Chief Executive Officer
SaleCommon Stock 10,000 $12.00 $120,000.00
Disclosure

SEC source: 0001209191-19-049870 · doc4.xml · nonDerivative · entry 2

Kauffman Michael · CIK 0001364719 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 529,767

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document
September 16, 2019 Filed Sep 17, 2019 20:56 UTC
Kauffman MichaelDirector · Chief Executive Officer
Exercise / conversionCommon Stock 10,000 $4.75 $47,520.00
Disclosure

SEC source: 0001209191-19-049870 · doc4.xml · nonDerivative · entry 1

Kauffman Michael · CIK 0001364719 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 539,767

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document
September 16, 2019 Filed Sep 17, 2019 20:54 UTC
Shacham SharonPresident & CSO
Exercise / conversionStock Option (right to buy) · Derivative 10,000 $0.00 Strike: $4.75 $0.00
Disclosure

SEC source: 0001209191-19-049868 · doc4.xml · derivative · entry 8

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 426,061

Underlying: Common Stock · 10,000 shares

Expires 2023-09-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the spouse of the reporting person.

F5 · derivative.exercise_date: This option, representing a right to purchase a specified number of shares, vested as to 25% of the shares on September 3, 2014, and the remaining 75% vested in 36 equal monthly installments thereafter.

Read SEC document
September 16, 2019 Filed Sep 17, 2019 20:54 UTC
Shacham SharonPresident & CSO
Exercise / conversionStock Option (right to buy) · Derivative 10,000 $0.00 Strike: $4.75 $0.00
Disclosure

SEC source: 0001209191-19-049868 · doc4.xml · derivative · entry 7

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 470,303

Underlying: Common Stock · 10,000 shares

Expires 2023-09-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F5 · derivative.exercise_date: This option, representing a right to purchase a specified number of shares, vested as to 25% of the shares on September 3, 2014, and the remaining 75% vested in 36 equal monthly installments thereafter.

Read SEC document
September 16, 2019 Filed Sep 17, 2019 20:54 UTC
Shacham SharonPresident & CSO
SaleCommon Stock 10,000 $12.00 $120,000.00
Disclosure

SEC source: 0001209191-19-049868 · doc4.xml · nonDerivative · entry 4

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 529,767

F2 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the spouse of the reporting person.

Read SEC document
September 16, 2019 Filed Sep 17, 2019 20:54 UTC
Shacham SharonPresident & CSO
Exercise / conversionCommon Stock 10,000 $4.75 $47,520.00
Disclosure

SEC source: 0001209191-19-049868 · doc4.xml · nonDerivative · entry 3

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 539,767

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the spouse of the reporting person.

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September 16, 2019 Filed Sep 17, 2019 20:54 UTC
Shacham SharonPresident & CSO
SaleCommon Stock 10,000 $12.00 $120,000.00
Disclosure

SEC source: 0001209191-19-049868 · doc4.xml · nonDerivative · entry 2

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 731,134

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

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September 16, 2019 Filed Sep 17, 2019 20:54 UTC
Shacham SharonPresident & CSO
Exercise / conversionCommon Stock 10,000 $4.75 $47,520.00
Disclosure

SEC source: 0001209191-19-049868 · doc4.xml · nonDerivative · entry 1

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 741,134

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

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July 11, 2019 Filed Jul 15, 2019 20:05 UTC
Shah JatinEVP, Chief Medical Officer
GrantRestricted Stock Units · Derivative 9,650 $0.00 $0.00
Disclosure

SEC source: 0001209191-19-042055 · doc4.xml · derivative · entry 2

Shah Jatin · CIK 0001782186 · EVP, Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,650

Underlying: Common Stock · 9,650 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of Karyopharm Therapeutics Inc. common stock.

F3 · derivative.exercise_date: The restricted stock units vest in four equal annual installments beginning July 11, 2020, the first anniversary of the grant date. Vested shares will be delivered to the reporting person as soon as possible following each vesting date, but in any event within 30 days of such date.

F3 · derivative.expiration_date: The restricted stock units vest in four equal annual installments beginning July 11, 2020, the first anniversary of the grant date. Vested shares will be delivered to the reporting person as soon as possible following each vesting date, but in any event within 30 days of such date.

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July 11, 2019 Filed Jul 15, 2019 20:05 UTC
Shah JatinEVP, Chief Medical Officer
GrantStock Option (right to buy) · Derivative 25,700 $0.00 Strike: $7.61 $0.00
Disclosure

SEC source: 0001209191-19-042055 · doc4.xml · derivative · entry 1

Shah Jatin · CIK 0001782186 · EVP, Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,700

Underlying: Common Stock · 25,700 shares

Expires 2029-07-10

F1 · derivative.exercise_date: This option was granted on July 11, 2019. The shares underlying this option vest as to 25% of the shares on July 11, 2020, with the remaining 75% vesting in 36 equal monthly installments thereafter.

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June 06, 2019 Filed Jun 7, 2019 12:54 UTC GrantNonstatutory Stock Option (right to buy) · Derivative 25,000 $0.00 Strike: $5.43 $0.00
Disclosure

SEC source: 0001209191-19-035374 · doc4.xml · derivative · entry 1

Dolsten Mikael · CIK 0001437590 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,000

Underlying: Common Stock · 25,000 shares

Expires 2029-06-05

F1 · derivative.exercise_date: This option vests as to 100% of the underlying shares on June 6, 2020, provided that the reporting person continues to serve as a director of the issuer through such date.

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June 06, 2019 Filed Jun 7, 2019 12:57 UTC GrantNonstatutory Stock Option (right to buy) · Derivative 25,000 $0.00 Strike: $5.43 $0.00
Disclosure

SEC source: 0001209191-19-035376 · doc4.xml · derivative · entry 1

Greene Barry E · CIK 0001291963 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,000

Underlying: Common Stock · 25,000 shares

Expires 2029-06-05

F1 · derivative.exercise_date: This option vests as to 100% of the underlying shares on June 6, 2020, provided that the reporting person continues to serve as a director of the issuer through such date.

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June 06, 2019 Filed Jun 7, 2019 12:59 UTC GrantNonstatutory Stock Option (right to buy) · Derivative 25,000 $0.00 Strike: $5.43 $0.00
Disclosure

SEC source: 0001209191-19-035378 · doc4.xml · derivative · entry 1

PAKIANATHAN DEEPIKA · CIK 0001270734 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,000

Underlying: Common Stock · 25,000 shares

Expires 2029-06-05

F1 · derivative.exercise_date: This option vests as to 100% of the underlying shares on June 6, 2020, provided that the reporting person continues to serve as a director of the issuer through such date.

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June 06, 2019 Filed Jun 7, 2019 12:53 UTC GrantNonstatutory Stock Option (right to buy) · Derivative 25,000 $0.00 Strike: $5.43 $0.00
Disclosure

SEC source: 0001209191-19-035373 · doc4.xml · derivative · entry 1

BOHLIN GAREN G · CIK 0001254705 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,000

Underlying: Common Stock · 25,000 shares

Expires 2029-06-05

F1 · derivative.exercise_date: This option vests as to 100% of the underlying shares on June 6, 2020, provided that the reporting person continues to serve as a director of the issuer through such date.

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June 06, 2019 Filed Jun 7, 2019 12:58 UTC GrantNonstatutory Stock Option (right to buy) · Derivative 25,000 $0.00 Strike: $5.43 $0.00
Disclosure

SEC source: 0001209191-19-035377 · doc4.xml · derivative · entry 1

Mirza Mansoor Raza · CIK 0001588389 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,000

Underlying: Common Stock · 25,000 shares

Expires 2029-06-05

F1 · derivative.exercise_date: This option vests as to 100% of the underlying shares on June 6, 2020, provided that the reporting person continues to serve as a director of the issuer through such date.

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June 06, 2019 Filed Jun 7, 2019 12:55 UTC GrantNonstatutory Stock Option (right to buy) · Derivative 25,000 $0.00 Strike: $5.43 $0.00
Disclosure

SEC source: 0001209191-19-035375 · doc4.xml · derivative · entry 1

Garland J. Scott · CIK 0001533228 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,000

Underlying: Common Stock · 25,000 shares

Expires 2029-06-05

F1 · derivative.exercise_date: This option vests as to 100% of the underlying shares on June 6, 2020, provided that the reporting person continues to serve as a director of the issuer through such date.

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February 28, 2019 Filed Mar 4, 2019 20:28 UTC
Chione Ltd10% owner
SaleCOMMON STOCK 149,624 $4.14 $619,114.19
Disclosure

SEC source: 0001213900-19-003551 · ownership.xml · nonDerivative · entry 1

Chione Ltd · CIK 0001590232 · 10% owner

Czernik Marcin · CIK 0001591275 · 10% owner

Hadjimichael Andreas · CIK 0001591256 · 10% owner

Hadjimichael George · CIK 0001674499 · 10% owner

Smolokowski Wiaczeslaw · CIK 0001591274 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,000,000

F1 · price: The price reported in Column 4 is a weighted average price. The shares were sold at prices ranging from $4.04 to $4.25, inclusive.

F2 · price: The reporting persons undertake to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in footnote 1 above.

F3 · balance_after: Shares of Common Stock are owned directly by Chione Limited ("Chione"). Chione's directors, Marcin Czernik, Andreas Hadjimichael and George Hadjimichael, may be deemed to share voting and investment power and beneficial ownership of the shares of Common Stock directly owned by Chione. Wiaczeslaw Smolokowski, the sole shareholder of Chione, may also be deemed to share voting and investment power and beneficial ownership of the shares of Common Stock directly owned by Chione.

F4 · balance_after: Each reporting person states that neither the filing of this Form 4 nor anything herein shall be deemed an admission that such person or any other person is, for purposes of Section 16 of the Securities Exchange Act of 1934, as amended (the "Act"), or otherwise, the beneficial owner of any securities covered by this Form 4. Beneficial ownership of the securities covered by this statement is disclaimed.

F5 · balance_after: Each reporting person may be deemed to be a member of a group with respect to the issuer or securities of the issuer for purposes of Section 13(d) or 13(g) of the Act. Each reporting person declares that neither the filing of this Form 4 nor anything herein shall be construed as an admission that such person or any other person is, for the purposes of Section 13(d) or 13(g) of the Act or any other purpose, a member of a group with respect to the issuer or securities of the issuer.

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February 27, 2019 Filed Feb 27, 2019 20:12 UTC
Chione Ltd10% owner
SaleCOMMON STOCK 558,243 $4.51 $2,515,833.73
Disclosure

SEC source: 0001213900-19-003242 · ownership.xml · nonDerivative · entry 3

Chione Ltd · CIK 0001590232 · 10% owner

Czernik Marcin · CIK 0001591275 · 10% owner

Hadjimichael Andreas · CIK 0001591256 · 10% owner

Hadjimichael George · CIK 0001674499 · 10% owner

Smolokowski Wiaczeslaw · CIK 0001591274 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,149,624

F1 · price: The prices reported in Column 4 are weighted average prices. The shares were sold on 02/25/2019 at prices ranging from $4.80 to $5.31, inclusive, on 02/26/2019 at prices ranging from $5.00 to $5.08, inclusive, and on 02/27/2019 at prices ranging from $4.40 to $4.675, inclusive.

F2 · price: The reporting persons undertake to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within each of the ranges set forth in footnote 1 above.

F3 · balance_after: Shares of Common Stock are owned directly by Chione Limited ("Chione"). Chione's directors, Marcin Czernik, Andreas Hadjimichael and George Hadjimichael, may be deemed to share voting and investment power and beneficial ownership of the shares of Common Stock directly owned by Chione. Wiaczeslaw Smolokowski, the sole shareholder of Chione, may also be deemed to share voting and investment power and beneficial ownership of the shares of Common Stock directly owned by Chione.

F4 · balance_after: Each reporting person states that neither the filing of this Form 4 nor anything herein shall be deemed an admission that such person or any other person is, for purposes of Section 16 of the Securities Exchange Act of 1934, as amended (the "Act"), or otherwise, the beneficial owner of any securities covered by this Form 4. Beneficial ownership of the securities covered by this statement is disclaimed.

F5 · balance_after: Each reporting person may be deemed to be a member of a group with respect to the issuer or securities of the issuer for purposes of Section 13(d) or 13(g) of the Act. Each reporting person declares that neither the filing of this Form 4 nor anything herein shall be construed as an admission that such person or any other person is, for the purposes of Section 13(d) or 13(g) of the Act or any other purpose, a member of a group with respect to the issuer or securities of the issuer.

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February 26, 2019 Filed Feb 27, 2019 20:12 UTC
Chione Ltd10% owner
SaleCOMMON STOCK 123,400 $5.00 $617,209.78
Disclosure

SEC source: 0001213900-19-003242 · ownership.xml · nonDerivative · entry 2

Chione Ltd · CIK 0001590232 · 10% owner

Czernik Marcin · CIK 0001591275 · 10% owner

Hadjimichael Andreas · CIK 0001591256 · 10% owner

Hadjimichael George · CIK 0001674499 · 10% owner

Smolokowski Wiaczeslaw · CIK 0001591274 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,707,867

F1 · price: The prices reported in Column 4 are weighted average prices. The shares were sold on 02/25/2019 at prices ranging from $4.80 to $5.31, inclusive, on 02/26/2019 at prices ranging from $5.00 to $5.08, inclusive, and on 02/27/2019 at prices ranging from $4.40 to $4.675, inclusive.

F2 · price: The reporting persons undertake to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within each of the ranges set forth in footnote 1 above.

F3 · balance_after: Shares of Common Stock are owned directly by Chione Limited ("Chione"). Chione's directors, Marcin Czernik, Andreas Hadjimichael and George Hadjimichael, may be deemed to share voting and investment power and beneficial ownership of the shares of Common Stock directly owned by Chione. Wiaczeslaw Smolokowski, the sole shareholder of Chione, may also be deemed to share voting and investment power and beneficial ownership of the shares of Common Stock directly owned by Chione.

F4 · balance_after: Each reporting person states that neither the filing of this Form 4 nor anything herein shall be deemed an admission that such person or any other person is, for purposes of Section 16 of the Securities Exchange Act of 1934, as amended (the "Act"), or otherwise, the beneficial owner of any securities covered by this Form 4. Beneficial ownership of the securities covered by this statement is disclaimed.

F5 · balance_after: Each reporting person may be deemed to be a member of a group with respect to the issuer or securities of the issuer for purposes of Section 13(d) or 13(g) of the Act. Each reporting person declares that neither the filing of this Form 4 nor anything herein shall be construed as an admission that such person or any other person is, for the purposes of Section 13(d) or 13(g) of the Act or any other purpose, a member of a group with respect to the issuer or securities of the issuer.

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February 25, 2019 Filed Feb 25, 2019 22:14 UTC
Mason MichaelSVP, CFO & Treasurer
GrantNonstatutory Stock Option (right to buy) · Derivative 150,000 $0.00 Strike: $5.06 $0.00
Disclosure

SEC source: 0001209191-19-013078 · doc4.xml · derivative · entry 1

Mason Michael · CIK 0001514291 · SVP, CFO & Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 150,000

Underlying: Common Stock · 150,000 shares

Expires 2029-02-24

F1 · derivative.exercise_date: This option was granted on February 25, 2019. The shares underlying this option vest as to 25% of the shares on February 25, 2020, with the remaining 75% vesting in 36 equal monthly installments thereafter.

Read SEC document
February 25, 2019 Filed Feb 27, 2019 20:12 UTC
Chione Ltd10% owner
SaleCOMMON STOCK 800,000 $4.99 $3,994,880.00
Disclosure

SEC source: 0001213900-19-003242 · ownership.xml · nonDerivative · entry 1

Chione Ltd · CIK 0001590232 · 10% owner

Czernik Marcin · CIK 0001591275 · 10% owner

Hadjimichael Andreas · CIK 0001591256 · 10% owner

Hadjimichael George · CIK 0001674499 · 10% owner

Smolokowski Wiaczeslaw · CIK 0001591274 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,831,267

F1 · price: The prices reported in Column 4 are weighted average prices. The shares were sold on 02/25/2019 at prices ranging from $4.80 to $5.31, inclusive, on 02/26/2019 at prices ranging from $5.00 to $5.08, inclusive, and on 02/27/2019 at prices ranging from $4.40 to $4.675, inclusive.

F2 · price: The reporting persons undertake to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within each of the ranges set forth in footnote 1 above.

F3 · balance_after: Shares of Common Stock are owned directly by Chione Limited ("Chione"). Chione's directors, Marcin Czernik, Andreas Hadjimichael and George Hadjimichael, may be deemed to share voting and investment power and beneficial ownership of the shares of Common Stock directly owned by Chione. Wiaczeslaw Smolokowski, the sole shareholder of Chione, may also be deemed to share voting and investment power and beneficial ownership of the shares of Common Stock directly owned by Chione.

F4 · balance_after: Each reporting person states that neither the filing of this Form 4 nor anything herein shall be deemed an admission that such person or any other person is, for purposes of Section 16 of the Securities Exchange Act of 1934, as amended (the "Act"), or otherwise, the beneficial owner of any securities covered by this Form 4. Beneficial ownership of the securities covered by this statement is disclaimed.

F5 · balance_after: Each reporting person may be deemed to be a member of a group with respect to the issuer or securities of the issuer for purposes of Section 13(d) or 13(g) of the Act. Each reporting person declares that neither the filing of this Form 4 nor anything herein shall be construed as an admission that such person or any other person is, for the purposes of Section 13(d) or 13(g) of the Act or any other purpose, a member of a group with respect to the issuer or securities of the issuer.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.