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Nasdaq · USD

IONS

IONIS PHARMACEUTICALS INC

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1182
SEC CIK
0000874015
Parsed reports
834

Last 12 months

Inside the activity.

2 purchase rows · 116 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 2025015
Dec 202502
Jan 2026029
Feb 202607
Mar 2026031
Apr 202609
May 202606
Jun 2026011
Jul 202626
Aug 202600
Sep 202600
Oct 202600

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
November 25, 2020 Filed Nov 30, 2020 23:46 UTC
Geary Richard SEVP, Development
SaleCommon Stock 11,920 $50.05 $596,596.00
Disclosure

SEC source: 0000874015-20-000156 · edgar.xml · nonDerivative · entry 2

Geary Richard S · CIK 0001442730 · EVP, Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,447

F2 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on October 7, 2019.

F3 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $49.85 to $50.25, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (3) of this Form 4.

Read SEC document
November 25, 2020 Filed Nov 30, 2020 23:46 UTC
Geary Richard SEVP, Development
Exercise / conversionCommon Stock 11,920 $39.87 $475,250.40
Disclosure

SEC source: 0000874015-20-000156 · edgar.xml · nonDerivative · entry 1

Geary Richard S · CIK 0001442730 · EVP, Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 42,367

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: Acquired as a result of exercising a stock option that was scheduled to expire on 1/1/21. The purchase reported on this Form 4 was effected pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on October 7, 2019.

Read SEC document
November 25, 2020 Filed Nov 30, 2020 23:44 UTC Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 3,590 $0.00 Strike: $39.87 $0.00
Disclosure

SEC source: 0000874015-20-000154 · edgar.xml · derivative · entry 3

PARSHALL B LYNNE · CIK 0001073385 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 0 shares

Expires 2021-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 25, 2020 Filed Nov 30, 2020 23:44 UTC SaleCommon Stock 3,590 $50.05 $179,679.50
Disclosure

SEC source: 0000874015-20-000154 · edgar.xml · nonDerivative · entry 2

PARSHALL B LYNNE · CIK 0001073385 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 67,464

F2 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on September 11, 2020.

F3 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $49.85-$50.25, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (3) of this Form 4.

Read SEC document
November 25, 2020 Filed Nov 30, 2020 23:44 UTC Exercise / conversionCommon Stock 3,590 $39.87 $143,133.30
Disclosure

SEC source: 0000874015-20-000154 · edgar.xml · nonDerivative · entry 1

PARSHALL B LYNNE · CIK 0001073385 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 71,054

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: Acquired as a result of exercising a stock option that was scheduled to expire on 1/1/21. The purchase reported on this Form 4 was effected pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on September 11, 2020.

Read SEC document
November 24, 2020 Filed Nov 26, 2020 00:04 UTC
CROOKE STANLEY TDirector · Exec Chairman of the Board
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 2,590 $0.00 Strike: $39.87 $0.00
Disclosure

SEC source: 0000874015-20-000152 · edgar.xml · derivative · entry 10

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,990

Underlying: Common Stock · 0 shares

Expires 2021-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 24, 2020 Filed Nov 26, 2020 00:04 UTC
CROOKE STANLEY TDirector · Exec Chairman of the Board
SaleCommon Stock 2,590 $50.83 $131,649.70
Disclosure

SEC source: 0000874015-20-000152 · edgar.xml · nonDerivative · entry 6

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,021

F4 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on March 13, 2019.

F6 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $50.50 to $51.00, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (6) of this Form 4.

Read SEC document
November 24, 2020 Filed Nov 26, 2020 00:04 UTC
CROOKE STANLEY TDirector · Exec Chairman of the Board
Exercise / conversionCommon Stock 2,590 $39.87 $103,263.30
Disclosure

SEC source: 0000874015-20-000152 · edgar.xml · nonDerivative · entry 5

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,611

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · shares: Acquired as a result of exercising a stock option that was scheduled to expire on 1/1/21. The purchase reported on this Form 4 was effected pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on March 13, 2019.

Read SEC document
November 24, 2020 Filed Nov 26, 2020 00:02 UTC
HOUGEN ELIZABETH LEVP, Finance & CFO
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 4,320 $0.00 Strike: $39.87 $0.00
Disclosure

SEC source: 0000874015-20-000150 · edgar.xml · derivative · entry 9

HOUGEN ELIZABETH L · CIK 0001074773 · EVP, Finance & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,680

Underlying: Common Stock · 0 shares

Expires 2021-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 24, 2020 Filed Nov 26, 2020 00:02 UTC
HOUGEN ELIZABETH LEVP, Finance & CFO
SaleCommon Stock 4,320 $50.83 $219,585.60
Disclosure

SEC source: 0000874015-20-000150 · edgar.xml · nonDerivative · entry 6

HOUGEN ELIZABETH L · CIK 0001074773 · EVP, Finance & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,495

F5 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on October 2, 2020.

F6 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $50.50 to $51.00, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (6) of this Form 4.

Read SEC document
November 24, 2020 Filed Nov 26, 2020 00:02 UTC
HOUGEN ELIZABETH LEVP, Finance & CFO
Exercise / conversionCommon Stock 4,320 $39.87 $172,238.40
Disclosure

SEC source: 0000874015-20-000150 · edgar.xml · nonDerivative · entry 5

HOUGEN ELIZABETH L · CIK 0001074773 · EVP, Finance & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,815

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · shares: Acquired as a result of exercising a stock option that was scheduled to expire on 1/1/21. The purchase reported on this Form 4 was effected pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on October 2, 2020.

Read SEC document
November 24, 2020 Filed Nov 25, 2020 23:58 UTC
Geary Richard SEVP, Development
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 2,380 $0.00 Strike: $39.87 $0.00
Disclosure

SEC source: 0000874015-20-000148 · edgar.xml · derivative · entry 6

Geary Richard S · CIK 0001442730 · EVP, Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,920

Underlying: Common Stock · 0 shares

Expires 2021-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 24, 2020 Filed Nov 25, 2020 23:58 UTC
Geary Richard SEVP, Development
SaleCommon Stock 2,380 $50.83 $120,975.40
Disclosure

SEC source: 0000874015-20-000148 · edgar.xml · nonDerivative · entry 4

Geary Richard S · CIK 0001442730 · EVP, Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,447

F2 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on October 7, 2019.

F4 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $50.50 to $51.00, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (4) of this Form 4.

Read SEC document
November 24, 2020 Filed Nov 25, 2020 23:58 UTC
Geary Richard SEVP, Development
Exercise / conversionCommon Stock 2,380 $39.87 $94,890.60
Disclosure

SEC source: 0000874015-20-000148 · edgar.xml · nonDerivative · entry 3

Geary Richard S · CIK 0001442730 · EVP, Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,827

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: Acquired as a result of exercising a stock option that was scheduled to expire on 1/1/21. The purchase reported on this Form 4 was effected pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on October 7, 2019.

Read SEC document
November 24, 2020 Filed Nov 25, 2020 23:56 UTC Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 710 $0.00 Strike: $39.87 $0.00
Disclosure

SEC source: 0000874015-20-000146 · edgar.xml · derivative · entry 6

PARSHALL B LYNNE · CIK 0001073385 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,590

Underlying: Common Stock · 0 shares

Expires 2021-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 24, 2020 Filed Nov 25, 2020 23:56 UTC SaleCommon Stock 710 $50.82 $36,082.20
Disclosure

SEC source: 0000874015-20-000146 · edgar.xml · nonDerivative · entry 4

PARSHALL B LYNNE · CIK 0001073385 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 67,464

F2 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on September 11, 2020.

F4 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $50.50 to $51.00, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (4) of this Form 4.

Read SEC document
November 24, 2020 Filed Nov 25, 2020 23:56 UTC Exercise / conversionCommon Stock 710 $39.87 $28,307.70
Disclosure

SEC source: 0000874015-20-000146 · edgar.xml · nonDerivative · entry 3

PARSHALL B LYNNE · CIK 0001073385 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 68,174

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: Acquired as a result of exercising a stock option that was scheduled to expire on 1/1/21. The purchase reported on this Form 4 was effected pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on September 11, 2020.

Read SEC document
November 23, 2020 Filed Nov 26, 2020 00:04 UTC
CROOKE STANLEY TDirector · Exec Chairman of the Board
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 11,600 $0.00 Strike: $39.87 $0.00
Disclosure

SEC source: 0000874015-20-000152 · edgar.xml · derivative · entry 9

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,580

Underlying: Common Stock · 0 shares

Expires 2021-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 23, 2020 Filed Nov 26, 2020 00:04 UTC
CROOKE STANLEY TDirector · Exec Chairman of the Board
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 500 $0.00 Strike: $39.87 $0.00
Disclosure

SEC source: 0000874015-20-000152 · edgar.xml · derivative · entry 8

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Indirect · by wife

Disclosed balance after: 0

Underlying: Common Stock · 0 shares

Expires 2021-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 23, 2020 Filed Nov 26, 2020 00:04 UTC
CROOKE STANLEY TDirector · Exec Chairman of the Board
SaleCommon Stock 11,600 $50.11 $581,276.00
Disclosure

SEC source: 0000874015-20-000152 · edgar.xml · nonDerivative · entry 4

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,021

F4 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on March 13, 2019.

F5 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $50.00 to $50.25, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (5) of this Form 4.

Read SEC document
November 23, 2020 Filed Nov 26, 2020 00:04 UTC
CROOKE STANLEY TDirector · Exec Chairman of the Board
Exercise / conversionCommon Stock 11,600 $39.87 $462,492.00
Disclosure

SEC source: 0000874015-20-000152 · edgar.xml · nonDerivative · entry 3

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,621

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · shares: Acquired as a result of exercising a stock option that was scheduled to expire on 1/1/21. The purchase reported on this Form 4 was effected pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on March 13, 2019.

Read SEC document
November 23, 2020 Filed Nov 26, 2020 00:04 UTC
CROOKE STANLEY TDirector · Exec Chairman of the Board
SaleCommon Stock 500 $50.00 $25,000.00
Disclosure

SEC source: 0000874015-20-000152 · edgar.xml · nonDerivative · entry 2

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Indirect · by wife

Disclosed balance after: 1,581

F2 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person's wife on March 13, 2019.

Read SEC document
November 23, 2020 Filed Nov 26, 2020 00:04 UTC
CROOKE STANLEY TDirector · Exec Chairman of the Board
Exercise / conversionCommon Stock 500 $39.87 $19,935.00
Disclosure

SEC source: 0000874015-20-000152 · edgar.xml · nonDerivative · entry 1

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Indirect · by wife

Disclosed balance after: 2,081

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: Acquired as a result of exercising a stock option that was scheduled to expire on 1/1/21. The purchase reported on this Form 4 was effected pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person's wife on March 13, 2019.

Read SEC document
November 23, 2020 Filed Nov 26, 2020 00:02 UTC
HOUGEN ELIZABETH LEVP, Finance & CFO
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 5,875 $0.00 Strike: $39.87 $0.00
Disclosure

SEC source: 0000874015-20-000150 · edgar.xml · derivative · entry 8

HOUGEN ELIZABETH L · CIK 0001074773 · EVP, Finance & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,000

Underlying: Common Stock · 0 shares

Expires 2021-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 23, 2020 Filed Nov 26, 2020 00:02 UTC
HOUGEN ELIZABETH LEVP, Finance & CFO
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 13,125 $0.00 Strike: $39.87 $0.00
Disclosure

SEC source: 0000874015-20-000150 · edgar.xml · derivative · entry 7

HOUGEN ELIZABETH L · CIK 0001074773 · EVP, Finance & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,875

Underlying: Common Stock · 0 shares

Expires 2021-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 23, 2020 Filed Nov 26, 2020 00:02 UTC
HOUGEN ELIZABETH LEVP, Finance & CFO
SaleCommon Stock 5,875 $50.11 $294,396.25
Disclosure

SEC source: 0000874015-20-000150 · edgar.xml · nonDerivative · entry 4

HOUGEN ELIZABETH L · CIK 0001074773 · EVP, Finance & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,495

F5 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on October 2, 2020.

F3 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $50.00 to $50.25, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (3) of this Form 4.

Read SEC document
November 23, 2020 Filed Nov 26, 2020 00:02 UTC
HOUGEN ELIZABETH LEVP, Finance & CFO
Exercise / conversionCommon Stock 5,875 $39.87 $234,236.25
Disclosure

SEC source: 0000874015-20-000150 · edgar.xml · nonDerivative · entry 3

HOUGEN ELIZABETH L · CIK 0001074773 · EVP, Finance & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,370

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · shares: Acquired as a result of exercising a stock option that was scheduled to expire on 1/1/21. The purchase reported on this Form 4 was effected pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on October 2, 2020.

Read SEC document
November 23, 2020 Filed Nov 26, 2020 00:02 UTC
HOUGEN ELIZABETH LEVP, Finance & CFO
SaleCommon Stock 13,125 $50.11 $657,693.75
Disclosure

SEC source: 0000874015-20-000150 · edgar.xml · nonDerivative · entry 2

HOUGEN ELIZABETH L · CIK 0001074773 · EVP, Finance & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,495

F2 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on February 3, 2015.

F3 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $50.00 to $50.25, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (3) of this Form 4.

Read SEC document
November 23, 2020 Filed Nov 26, 2020 00:02 UTC
HOUGEN ELIZABETH LEVP, Finance & CFO
Exercise / conversionCommon Stock 13,125 $39.87 $523,293.75
Disclosure

SEC source: 0000874015-20-000150 · edgar.xml · nonDerivative · entry 1

HOUGEN ELIZABETH L · CIK 0001074773 · EVP, Finance & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,620

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: Acquired as a result of exercising a stock option that was scheduled to expire on 1/1/21. The purchase reported on this Form 4 was effected pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on February 3, 2015.

Read SEC document
November 23, 2020 Filed Nov 25, 2020 23:58 UTC
Geary Richard SEVP, Development
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 10,700 $0.00 Strike: $39.87 $0.00
Disclosure

SEC source: 0000874015-20-000148 · edgar.xml · derivative · entry 5

Geary Richard S · CIK 0001442730 · EVP, Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,300

Underlying: Common Stock · 0 shares

Expires 2021-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 23, 2020 Filed Nov 25, 2020 23:58 UTC
Geary Richard SEVP, Development
SaleCommon Stock 10,700 $50.11 $536,177.00
Disclosure

SEC source: 0000874015-20-000148 · edgar.xml · nonDerivative · entry 2

Geary Richard S · CIK 0001442730 · EVP, Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,447

F2 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on October 7, 2019.

F3 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $50.00 to $50.25, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (3) of this Form 4.

Read SEC document
November 23, 2020 Filed Nov 25, 2020 23:58 UTC
Geary Richard SEVP, Development
Exercise / conversionCommon Stock 10,700 $39.87 $426,609.00
Disclosure

SEC source: 0000874015-20-000148 · edgar.xml · nonDerivative · entry 1

Geary Richard S · CIK 0001442730 · EVP, Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,147

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: Acquired as a result of exercising a stock option that was scheduled to expire on 1/1/21. The purchase reported on this Form 4 was effected pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on October 7, 2019.

Read SEC document
November 23, 2020 Filed Nov 25, 2020 23:56 UTC Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 3,200 $0.00 Strike: $39.87 $0.00
Disclosure

SEC source: 0000874015-20-000146 · edgar.xml · derivative · entry 5

PARSHALL B LYNNE · CIK 0001073385 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,300

Underlying: Common Stock · 0 shares

Expires 2021-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 23, 2020 Filed Nov 25, 2020 23:56 UTC SaleCommon Stock 3,200 $50.12 $160,384.00
Disclosure

SEC source: 0000874015-20-000146 · edgar.xml · nonDerivative · entry 2

PARSHALL B LYNNE · CIK 0001073385 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 67,464

F2 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on September 11, 2020.

F3 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $50.00 to $50.25, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (3) of this Form 4.

Read SEC document
November 23, 2020 Filed Nov 25, 2020 23:56 UTC Exercise / conversionCommon Stock 3,200 $39.87 $127,584.00
Disclosure

SEC source: 0000874015-20-000146 · edgar.xml · nonDerivative · entry 1

PARSHALL B LYNNE · CIK 0001073385 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 70,664

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: Acquired as a result of exercising a stock option that was scheduled to expire on 1/1/21. The purchase reported on this Form 4 was effected pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on September 11, 2020.

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November 19, 2020 Filed Jan 7, 2021 02:17 UTC
CROOKE STANLEY TDirector · Executive Chairman of Board
GiftCommon Stock 31,000 $0.00 $0.00
Disclosure

SEC source: 0000874015-21-000015 · edgar.xml · nonDerivative · entry 1

CROOKE STANLEY T · CIK 0000897667 · Director · Executive Chairman of Board

10b5-1 filing: Not disclosed

Ownership: Indirect · By trust

Disclosed balance after: 569,391

F1 · kind: Represents a bona fide gift to a charitable organization.

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November 03, 2020 Filed Nov 6, 2020 01:26 UTC
BENNETT C FRANKChief Scientific Officer
Exercise / conversionEmployee Stock Option (right to buy) · Derivative 15,000 $0.00 Strike: $39.87 $0.00
Disclosure

SEC source: 0000874015-20-000144 · edgar.xml · derivative · entry 3

BENNETT C FRANK · CIK 0001073387 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 15,000 shares

Expires 2021-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

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November 03, 2020 Filed Nov 6, 2020 01:26 UTC
BENNETT C FRANKChief Scientific Officer
SaleCommon Stock 15,000 $46.77 $701,599.50
Disclosure

SEC source: 0000874015-20-000144 · edgar.xml · nonDerivative · entry 2

BENNETT C FRANK · CIK 0001073387 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,476

F1 · shares: Acquired as a result of exercising a stock option pursuant to a Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on May 14, 2020.

F2 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $46.50-$46.90, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (2) of this Form 4.

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November 03, 2020 Filed Nov 6, 2020 01:26 UTC
BENNETT C FRANKChief Scientific Officer
Exercise / conversionCommon Stock 15,000 $39.87 $598,050.00
Disclosure

SEC source: 0000874015-20-000144 · edgar.xml · nonDerivative · entry 1

BENNETT C FRANK · CIK 0001073387 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 47,476

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: Acquired as a result of exercising a stock option pursuant to a Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on May 14, 2020.

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October 20, 2020 Filed Oct 22, 2020 21:36 UTC SaleCommon Stock 2,889 $46.86 $135,385.76
Disclosure

SEC source: 0000874015-20-000138 · edgar.xml · nonDerivative · entry 1

KLEIN JOSEPH III · CIK 0001206369 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,794

F1 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on September 18, 2020

F2 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $46.33 to $47.15, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (2) of this Form 4

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October 15, 2020 Filed Oct 19, 2020 21:50 UTC Exercise / conversionRestricted Stock Units · Derivative 1,778 $0.00 $0.00
Disclosure

SEC source: 0000874015-20-000136 · edgar.xml · derivative · entry 2

Hayden Michael R · CIK 0001352908 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,554

Underlying: Common Stock · 1,778 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each Restricted Stock Unit represents a contingent right to receive one share of Ionis common stock, or its equivalent cash value.

F3 · derivative.exercise_date: Restricted Stock Units vest in four equal annual installments. Upon vesting, the Restricted Stock Units will be paid out in whole shares of Ionis common stock or cash as may be determined by Ionis.

F3 · derivative.expiration_date: Restricted Stock Units vest in four equal annual installments. Upon vesting, the Restricted Stock Units will be paid out in whole shares of Ionis common stock or cash as may be determined by Ionis.

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October 15, 2020 Filed Oct 19, 2020 21:50 UTC Exercise / conversionCommon Stock 1,778 $0.00 $0.00
Disclosure

SEC source: 0000874015-20-000136 · edgar.xml · nonDerivative · entry 1

Hayden Michael R · CIK 0001352908 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,334

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired pursuant to vesting and release of shares pursuant to Restricted Stock Unit awards.

F1 · shares: Acquired pursuant to vesting and release of shares pursuant to Restricted Stock Unit awards.

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October 15, 2020 Filed Oct 19, 2020 21:46 UTC Exercise / conversionRestricted Stock Units · Derivative 1,778 $0.00 $0.00
Disclosure

SEC source: 0000874015-20-000133 · edgar.xml · derivative · entry 2

Reikes Peter N · CIK 0001753652 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,554

Underlying: Common Stock · 1,778 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each Restricted Stock Unit represents a contingent right to receive one share of Ionis common stock, or its equivalent cash value.

F3 · derivative.exercise_date: These Restricted Stock Units vest in four equal annual installments. Upon vesting, the Restricted Stock Units will be paid out in whole shares of Ionis common stock or cash as may be determined by the Company.

F3 · derivative.expiration_date: These Restricted Stock Units vest in four equal annual installments. Upon vesting, the Restricted Stock Units will be paid out in whole shares of Ionis common stock or cash as may be determined by the Company.

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October 15, 2020 Filed Oct 19, 2020 21:46 UTC Exercise / conversionCommon Stock 1,778 $0.00 $0.00
Disclosure

SEC source: 0000874015-20-000133 · edgar.xml · nonDerivative · entry 1

Reikes Peter N · CIK 0001753652 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,334

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired pursuant to vesting and release of shares pursuant to Restricted Stock Unit awards.

F1 · shares: Acquired pursuant to vesting and release of shares pursuant to Restricted Stock Unit awards.

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September 22, 2020 Filed Sep 23, 2020 22:44 UTC
CROOKE STANLEY TDirector · Exec Chairman of the Board
SaleCommon Stock 50,000 $50.41 $2,520,460.00
Disclosure

SEC source: 0000874015-20-000131 · edgar.xml · nonDerivative · entry 2

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Indirect · By trust

Disclosed balance after: 650,391

F2 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on January 2, 2020

F3 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $50.02 to $50.70, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (4) of this Form 4

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September 21, 2020 Filed Sep 23, 2020 22:44 UTC
CROOKE STANLEY TDirector · Exec Chairman of the Board
SaleCommon Stock 2,000 $50.18 $100,360.00
Disclosure

SEC source: 0000874015-20-000131 · edgar.xml · nonDerivative · entry 1

CROOKE STANLEY T · CIK 0000897667 · Director · Exec Chairman of the Board

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 1,581

F1 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person's wife on January 2, 2020.

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September 16, 2020 Filed Sep 18, 2020 21:45 UTC Exercise / conversionDirector Stock Option (right to buy) · Derivative 11,250 $0.00 Strike: $28.47 $0.00
Disclosure

SEC source: 0000874015-20-000129 · edgar.xml · derivative · entry 4

WENDER JOSEPH H · CIK 0001073384 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 11,250 shares

Expires 2023-06-30

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
September 16, 2020 Filed Sep 18, 2020 21:45 UTC Exercise / conversionDirector Stock Option (right to buy) · Derivative 11,250 $0.00 Strike: $12.94 $0.00
Disclosure

SEC source: 0000874015-20-000129 · edgar.xml · derivative · entry 3

WENDER JOSEPH H · CIK 0001073384 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 11,250 shares

Expires 2022-07-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
September 16, 2020 Filed Sep 18, 2020 21:45 UTC Exercise / conversionCommon Stock 11,250 $28.47 $320,287.50
Disclosure

SEC source: 0000874015-20-000129 · edgar.xml · nonDerivative · entry 2

WENDER JOSEPH H · CIK 0001073384 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By Joseph H. Wender Trust

Disclosed balance after: 88,305

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired as a result of exercising a stock option.

F1 · shares: Acquired as a result of exercising a stock option.

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September 16, 2020 Filed Sep 18, 2020 21:45 UTC Exercise / conversionCommon Stock 11,250 $12.94 $145,575.00
Disclosure

SEC source: 0000874015-20-000129 · edgar.xml · nonDerivative · entry 1

WENDER JOSEPH H · CIK 0001073384 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By Joseph H. Wender Trust

Disclosed balance after: 77,055

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired as a result of exercising a stock option.

F1 · shares: Acquired as a result of exercising a stock option.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.