INSM

SEC source: 0001140361-21-008313 · form4.xml · nonDerivative · entry 1

Schaeffer Orlov S Nicole · CIK 0001401017 · Chief People Strategy Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,629

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001140361-21-007636 · form4.xml · nonDerivative · entry 1

ENGELSEN STEINAR J · CIK 0001218860 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 299,009

SEC source: 0001104659-21-019794 · tm213966-3_4seq1.xml · derivative · entry 6

Pellizzari Christine A · CIK 0001127430 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 15,150 shares

Expires 2026-05-19

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: twenty five percent (25%) vested on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vested on each six-month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001104659-21-019794 · tm213966-3_4seq1.xml · nonDerivative · entry 4

Pellizzari Christine A · CIK 0001127430 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 140,721

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · price: This is the weighted average sales price representing 15,150 shares sold at prices ranging from $44.75 to $45.44 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001104659-21-019794 · tm213966-3_4seq1.xml · nonDerivative · entry 3

Pellizzari Christine A · CIK 0001127430 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 155,871

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

SEC source: 0001104659-21-019794 · tm213966-3_4seq1.xml · derivative · entry 5

Pellizzari Christine A · CIK 0001127430 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,150

Underlying: Common Stock · 6,400 shares

Expires 2026-05-19

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: twenty five percent (25%) vested on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vested on each six-month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001104659-21-019794 · tm213966-3_4seq1.xml · nonDerivative · entry 2

Pellizzari Christine A · CIK 0001127430 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 140,721

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · price: This is the weighted average sales price representing 6,400 shares sold at prices ranging from $43.75 to $44.15 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001104659-21-019794 · tm213966-3_4seq1.xml · nonDerivative · entry 1

Pellizzari Christine A · CIK 0001127430 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 147,121

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

SEC source: 0001104659-21-008179 · tm213966-2_4seq1.xml · derivative · entry 9

Pellizzari Christine A · CIK 0001127430 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,550

Underlying: Common Stock · 2,600 shares

Expires 2026-05-19

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: twenty five percent (25%) vested on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vested on each six-month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001104659-21-008179 · tm213966-2_4seq1.xml · nonDerivative · entry 6

Pellizzari Christine A · CIK 0001127430 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 140,721

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4 · price: This is the weighted average sales price representing 2,600 shares sold at prices ranging from $43.75 to $44.23 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request

SEC source: 0001104659-21-008179 · tm213966-2_4seq1.xml · nonDerivative · entry 5

Pellizzari Christine A · CIK 0001127430 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 143,321

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

SEC source: 0001104659-21-008179 · tm213966-2_4seq1.xml · derivative · entry 8

Pellizzari Christine A · CIK 0001127430 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,150

Underlying: Common Stock · 6,000 shares

Expires 2026-05-19

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: twenty five percent (25%) vested on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vested on each six-month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001104659-21-008179 · tm213966-2_4seq1.xml · derivative · entry 7

Pellizzari Christine A · CIK 0001127430 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,150

Underlying: Common Stock · 15,000 shares

Expires 2026-05-19

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: twenty five percent (25%) vested on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vested on each six-month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001104659-21-008179 · tm213966-2_4seq1.xml · nonDerivative · entry 4

Pellizzari Christine A · CIK 0001127430 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 140,721

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · price: This is the weighted average sales price representing 6,000 shares sold at prices ranging from $43.75 to $43.94 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001104659-21-008179 · tm213966-2_4seq1.xml · nonDerivative · entry 3

Pellizzari Christine A · CIK 0001127430 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 146,721

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

SEC source: 0001104659-21-008179 · tm213966-2_4seq1.xml · nonDerivative · entry 2

Pellizzari Christine A · CIK 0001127430 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 140,721

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · price: This is the weighted average sales price representing 15,000 shares sold at prices ranging from $42.75 to $43.58 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001104659-21-008179 · tm213966-2_4seq1.xml · nonDerivative · entry 1

Pellizzari Christine A · CIK 0001127430 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 155,721

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

SEC source: 0001104659-21-006698 · tm213966-1_4seq1.xml · derivative · entry 9

Pellizzari Christine A · CIK 0001127430 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,150

Underlying: Common Stock · 10,000 shares

Expires 2026-05-19

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001104659-21-006698 · tm213966-1_4seq1.xml · derivative · entry 8

Pellizzari Christine A · CIK 0001127430 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 55,150

Underlying: Common Stock · 10,000 shares

Expires 2026-05-19

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001104659-21-006698 · tm213966-1_4seq1.xml · nonDerivative · entry 6

Pellizzari Christine A · CIK 0001127430 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 140,721

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4 · price: This is the weighted average sales price representing 10,000 shares sold at prices ranging from $41.75 to $42.19 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001104659-21-006698 · tm213966-1_4seq1.xml · nonDerivative · entry 5

Pellizzari Christine A · CIK 0001127430 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 150,721

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

SEC source: 0001104659-21-006698 · tm213966-1_4seq1.xml · nonDerivative · entry 4

Pellizzari Christine A · CIK 0001127430 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 140,721

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · price: This is the weighted average sales price representing 10,000 shares sold at prices ranging from $40.75 to $41.60 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001104659-21-006698 · tm213966-1_4seq1.xml · nonDerivative · entry 3

Pellizzari Christine A · CIK 0001127430 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 150,721

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

SEC source: 0001140361-21-017411 · form4.xml · nonDerivative · entry 5

SHAROKY MELVIN MD · CIK 0001182633 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By Melvin Sharoky C/F Sophie C. Wink UTMA/FL

Disclosed balance after: 184

F2 · kind: The reported transactions involved a gift of securities by the Reporting Person to an investment account, Melvin Sharoky C/F Sophie C. Wink UTMA/FL, for the benefit of the Reporting Person's granddaughter. The Reporting Person is the custodian of Melvin Sharoky C/F Sophie C. Wink UTMA/FL.

SEC source: 0001140361-21-017411 · form4.xml · nonDerivative · entry 4

SHAROKY MELVIN MD · CIK 0001182633 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 229,318

F2 · kind: The reported transactions involved a gift of securities by the Reporting Person to an investment account, Melvin Sharoky C/F Sophie C. Wink UTMA/FL, for the benefit of the Reporting Person's granddaughter. The Reporting Person is the custodian of Melvin Sharoky C/F Sophie C. Wink UTMA/FL.

SEC source: 0001140361-21-017411 · form4.xml · nonDerivative · entry 3

SHAROKY MELVIN MD · CIK 0001182633 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By spouse

Disclosed balance after: 847

F1 · kind: The reported transactions involved a gift of securities by the Reporting Person to his spouse.

SEC source: 0001140361-21-017411 · form4.xml · nonDerivative · entry 2

SHAROKY MELVIN MD · CIK 0001182633 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 229,502

F1 · kind: The reported transactions involved a gift of securities by the Reporting Person to his spouse.

SEC source: 0001104659-21-006698 · tm213966-1_4seq1.xml · derivative · entry 7

Pellizzari Christine A · CIK 0001127430 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 65,150

Underlying: Common Stock · 10,000 shares

Expires 2026-05-19

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001104659-21-006698 · tm213966-1_4seq1.xml · nonDerivative · entry 2

Pellizzari Christine A · CIK 0001127430 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 140,721

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · price: This is the weighted average sales price representing 10,000 shares sold at prices ranging from $39.75 to $40.08 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001104659-21-006698 · tm213966-1_4seq1.xml · nonDerivative · entry 1

Pellizzari Christine A · CIK 0001127430 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 150,721

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

SEC source: 0001140361-21-017411 · form4.xml · nonDerivative · entry 1

SHAROKY MELVIN MD · CIK 0001182633 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 230,349

SEC source: 0001104659-21-002513 · tm211774-13_4seq1.xml · derivative · entry 2

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,600

Underlying: Common Stock · 45,600 shares

Expires 2031-01-07

F3 · derivative.exercise_date: Stock options granted under the Company's 2019 Incentive Plan. The options become exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001104659-21-002513 · tm211774-13_4seq1.xml · nonDerivative · entry 1

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,183

F1 · shares: Restricted stock units granted pursuant to the Company's 2019 Incentive Plan. The Restricted Stock Units vest and become available as follows: twenty five (25%) percent on each anniversary of the date of grant through the fourth anniversary date of the grant.

F2 · price: Each Restricted Stock Unit was received as a grant on January 7, 2021, for no consideration, and represents a contingent right to receive one share of Common Stock.

SEC source: 0001104659-21-002514 · tm211774-14_4seq1.xml · derivative · entry 2

Flammer Martina M.D. · CIK 0001796960 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 54,720

Underlying: Common Stock · 54,720 shares

Expires 2031-01-07

F3 · derivative.exercise_date: Stock options granted under the Company's 2019 Incentive Plan. The options become exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001104659-21-002514 · tm211774-14_4seq1.xml · nonDerivative · entry 1

Flammer Martina M.D. · CIK 0001796960 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,596

F1 · shares: Restricted stock units granted pursuant to the Company's 2019 Incentive Plan. The Restricted Stock Units vest and become available as follows: twenty five (25%) percent on each anniversary of the date of grant through the fourth anniversary date of the grant.

F2 · price: Each Restricted Stock Unit was received as a grant on January 7, 2021, for no consideration, and represents a contingent right to receive one share of Common Stock.

SEC source: 0001104659-21-002512 · tm211774-12_4seq1.xml · derivative · entry 2

Adsett Roger · CIK 0001685904 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 54,720

Underlying: Common Stock · 54,720 shares

Expires 2031-01-07

F3 · derivative.exercise_date: Stock options granted under the Company's 2019 Incentive Plan. The options become exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001104659-21-002512 · tm211774-12_4seq1.xml · nonDerivative · entry 1

Adsett Roger · CIK 0001685904 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 98,552

F1 · shares: Restricted stock units granted pursuant to the Company's 2019 Incentive Plan. The Restricted Stock Units vest and become available as follows: twenty five (25%) percent on each anniversary of the date of grant through the fourth anniversary date of the grant.

F2 · price: Each Restricted Stock Unit was received as a grant on January 7, 2021, for no consideration, and represents a contingent right to receive one share of Common Stock.

SEC source: 0001104659-21-002508 · tm211774-10_4seq1.xml · derivative · entry 2

Pellizzari Christine A · CIK 0001127430 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,600

Underlying: Common Stock · 45,600 shares

Expires 2031-01-07

F3 · derivative.exercise_date: Stock options granted under the Company's 2019 Incentive Plan. The options become exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001104659-21-002508 · tm211774-10_4seq1.xml · nonDerivative · entry 1

Pellizzari Christine A · CIK 0001127430 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 140,721

F1 · shares: Restricted stock units granted pursuant to the Company's 2019 Incentive Plan. The Restricted Stock Units vest and become available as follows: twenty five (25%) percent on each anniversary of the date of grant through the fourth anniversary date of the grant.

F2 · price: Each Restricted Stock Unit was received as a grant on January 7, 2021, for no consideration, and represents a contingent right to receive one share of Common Stock.

SEC source: 0001104659-21-002510 · tm211774-11_4seq1.xml · derivative · entry 2

Lewis William · CIK 0001402051 · Director · Chair & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 109,440

Underlying: Common Stock · 109,440 shares

Expires 2031-01-07

F3 · derivative.exercise_date: Stock options granted under the Company's 2019 Incentive Plan. The options become exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001104659-21-002510 · tm211774-11_4seq1.xml · nonDerivative · entry 1

Lewis William · CIK 0001402051 · Director · Chair & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 179,608

F1 · shares: Restricted stock units granted pursuant to the Company's 2019 Incentive Plan. The Restricted Stock Units vest and become available as follows: twenty five (25%) percent on each anniversary of the date of grant through the fourth anniversary date of the grant.

F2 · price: Each Restricted Stock Unit was received as a grant on January 7, 2021, for no consideration, and represents a contingent right to receive one share of Common Stock.

SEC source: 0001104659-21-002506 · tm211774-9_4seq1.xml · derivative · entry 2

Schaeffer Orlov S Nicole · CIK 0001401017 · Chief People Strategy Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,480

Underlying: Common Stock · 36,480 shares

Expires 2031-01-07

F3 · derivative.exercise_date: Stock options granted under the Company's 2019 Incentive Plan. The options become exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001104659-21-002506 · tm211774-9_4seq1.xml · nonDerivative · entry 1

Schaeffer Orlov S Nicole · CIK 0001401017 · Chief People Strategy Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,920

F1 · shares: Restricted stock units granted pursuant to the Company's 2019 Incentive Plan. The Restricted Stock Units vest and become available as follows: twenty five (25%) percent on each anniversary of the date of grant through the fourth anniversary date of the grant.

F2 · price: Each Restricted Stock Unit was received as a grant on January 7, 2021, for no consideration, and represents a contingent right to receive one share of Common Stock.

SEC source: 0001104659-21-002505 · tm211774-8_4seq1.xml · derivative · entry 2

SORIANO JOHN · CIK 0001740947 · Chief Compliance Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,360

Underlying: Common Stock · 27,360 shares

Expires 2031-01-07

F3 · derivative.exercise_date: Stock options granted under the Company's 2019 Incentive Plan. The options become exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001104659-21-002505 · tm211774-8_4seq1.xml · nonDerivative · entry 1

SORIANO JOHN · CIK 0001740947 · Chief Compliance Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,773

F1 · shares: Restricted stock units granted pursuant to the Company's 2019 Incentive Plan. The Restricted Stock Units vest and become available as follows: twenty five (25%) percent on each anniversary of the date of grant through the fourth anniversary date of the grant.

F2 · price: Each Restricted Stock Unit was received as a grant on January 7, 2021, for no consideration, and represents a contingent right to receive one share of Common Stock.

SEC source: 0001104659-21-001607 · tm211774d6_4.xml · nonDerivative · entry 2

Lewis William · CIK 0001402051 · Chair & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 157,569

F1 · shares: Shares withheld by the Company to satisfy tax withholding requirements on vesting of time-based restricted stock units.

SEC source: 0001104659-21-001605 · tm211774d4_4seq1.xml · nonDerivative · entry 3

Adsett Roger · CIK 0001685904 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 87,533

F2 · shares: Shares withheld by the Company to satisfy tax withholding requirements on vesting of time-based restricted stock units.

SEC source: 0001104659-21-001604 · tm211774d3_4seq1.xml · nonDerivative · entry 2

Pellizzari Christine A · CIK 0001127430 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 131,538

F1 · shares: Shares withheld by the Company to satisfy tax withholding requirements on vesting of time-based restricted stock units.

SEC source: 0001104659-21-001602 · tm211774-2_4seq1.xml · nonDerivative · entry 2

Schaeffer Orlov S Nicole · CIK 0001401017 · Chief People Strategy Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,574

F1 · shares: Shares withheld by the Company to satisfy tax withholding requirements on vesting of time-based restricted stock units.

SEC source: 0001104659-21-001601 · tm211774-1_4seq1.xml · derivative · entry 29

Lewis William · CIK 0001402051 · Director · Chair & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By spouse

Disclosed balance after: 0

Underlying: Common Stock · 245,950 shares

Expires 2026-05-19

F6 · kind: The reported transactions involve transfers of options from the reporting person's spouse to a family trust, ARTICLE 4 TRUST UNDER KATIE PROCTER DYNASTY TRUST, of which the reporting person is a trustee. The reporting person and members of the reporting person's immediate family are the sole beneficiaries of the trust.

F2 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: twenty five percent (25%) vested on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant. All options are currently exercisable.