INSM

SEC source: 0001140361-22-001605 · form4.xml · nonDerivative · entry 1

Schaeffer Orlov S Nicole · CIK 0001401017 · Chief People Strategy Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 56,961

F1 · kind: Shares sold to satisfy withholding tax obligations upon the vesting of restricted stock units and to cover related broker fees.

SEC source: 0001140361-22-001602 · form4.xml · nonDerivative · entry 1

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 35,979

F1 · kind: Shares sold to satisfy withholding tax obligations upon the vesting of restricted stock units and to cover related broker fees.

SEC source: 0001140361-22-001603 · form4.xml · nonDerivative · entry 1

Flammer Martina M.D. · CIK 0001796960 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 46,038

F1 · kind: Shares sold to satisfy withholding tax obligations upon the vesting of restricted stock units and to cover related broker fees.

SEC source: 0001140361-22-000963 · form4.xml · nonDerivative · entry 2

Adsett Roger · CIK 0001685904 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 105,420

F1 · kind: Shares sold to satisfy withholding tax obligations upon the vesting of restricted stock units and to cover related broker fees.

SEC source: 0001140361-22-000961 · form4.xml · nonDerivative · entry 2

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 189,756

F1 · kind: Shares sold to satisfy withholding tax obligations upon the vesting of restricted stock units and to cover related broker fees.

SEC source: 0001140361-22-000956 · form4.xml · nonDerivative · entry 2

Schaeffer Orlov S Nicole · CIK 0001401017 · Chief People Strategy Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 48,428

F1 · kind: Shares sold to satisfy withholding tax obligations upon the vesting of restricted stock units and to cover related broker fees.

SEC source: 0001140361-22-000953 · form4.xml · nonDerivative · entry 2

Smith Michael Alexander · CIK 0001870278 · General Counsel, Senior VP

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,375

F1 · kind: Shares sold to satisfy withholding tax obligations upon the vesting of restricted stock units and to cover related broker fees.

SEC source: 0001140361-22-001167 · form4.xml · derivative · entry 2

Adsett Roger · CIK 0001685904 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 85,690

Underlying: Common Stock · 85,690 shares

Expires 2032-01-06

F3 · derivative.exercise_date: Stock options granted under the Company's 2019 Incentive Plan. The options become exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001140361-22-001167 · form4.xml · nonDerivative · entry 1

Adsett Roger · CIK 0001685904 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 123,155

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock, granted pursuant to the Company's 2019 Incentive Plan. The Restricted Stock Units vest and become available as follows: twenty five (25%) percent on each anniversary of the date of grant through the fourth anniversary date of the grant.

F2 · price: Each Restricted Stock Unit was received as a grant on January 6, 2022, for no consideration.

SEC source: 0001140361-22-001165 · form4.xml · derivative · entry 2

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 62,840

Underlying: Common Stock · 62,840 shares

Expires 2032-01-06

F4 · derivative.exercise_date: Stock options granted under the Company's 2019 Incentive Plan. The options become exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001140361-22-001165 · form4.xml · nonDerivative · entry 1

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 37,133

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock, granted pursuant to the Company's 2019 Incentive Plan. The Restricted Stock Units vest and become available as follows: twenty five (25%) percent on each anniversary of the date of grant through the fourth anniversary date of the grant.

F2 · price: Each Restricted Stock Unit was received as a grant on January 6, 2022, for no consideration.

F3 · balance_after: Includes 772 shares acquired through the Company's 2018 Employee Stock Purchase Plan.

SEC source: 0001140361-22-001166 · form4.xml · derivative · entry 2

Flammer Martina M.D. · CIK 0001796960 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 68,560

Underlying: Common Stock · 68,560 shares

Expires 2032-01-06

F3 · derivative.exercise_date: Stock options granted under the Company's 2019 Incentive Plan. The options become exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001140361-22-001166 · form4.xml · nonDerivative · entry 1

Flammer Martina M.D. · CIK 0001796960 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 47,533

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock, granted pursuant to the Company's 2019 Incentive Plan. The Restricted Stock Units vest and become available as follows: twenty five (25%) percent on each anniversary of the date of grant through the fourth anniversary date of the grant.

F2 · price: Each Restricted Stock Unit was received as a grant on January 6, 2022, for no consideration.

SEC source: 0001140361-22-001164 · form4.xml · derivative · entry 2

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 148,540

Underlying: Common Stock · 148,540 shares

Expires 2032-01-06

F3 · derivative.exercise_date: Stock options granted under the Company's 2019 Incentive Plan. The options become exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001140361-22-001164 · form4.xml · nonDerivative · entry 1

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 220,497

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock, granted pursuant to the Company's 2019 Incentive Plan. The Restricted Stock Units vest and become available as follows: twenty five (25%) percent on each anniversary of the date of grant through the fourth anniversary date of the grant.

F2 · price: Each Restricted Stock Unit was received as a grant on January 6, 2022, for no consideration.

SEC source: 0001140361-22-001162 · form4.xml · derivative · entry 2

Smith Michael Alexander · CIK 0001870278 · General Counsel, Senior VP

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,700

Underlying: Common Stock · 45,700 shares

Expires 2032-01-06

F3 · derivative.exercise_date: Stock options granted under the Company's 2019 Incentive Plan. The options become exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001140361-22-001162 · form4.xml · nonDerivative · entry 1

Smith Michael Alexander · CIK 0001870278 · General Counsel, Senior VP

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 37,833

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock, granted pursuant to the Company's 2019 Incentive Plan. The Restricted Stock Units vest and become available as follows: twenty five (25%) percent on each anniversary of the date of grant through the fourth anniversary date of the grant.

F2 · price: Each Restricted Stock Unit was received as a grant on January 6, 2022, for no consideration.

SEC source: 0001140361-22-001168 · form4.xml · derivative · entry 2

Schaeffer Orlov S Nicole · CIK 0001401017 · Chief People Strategy Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,700

Underlying: Common Stock · 45,700 shares

Expires 2032-01-06

F3 · derivative.exercise_date: Stock options granted under the Company's 2019 Incentive Plan. The options become exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001140361-22-001168 · form4.xml · nonDerivative · entry 1

Schaeffer Orlov S Nicole · CIK 0001401017 · Chief People Strategy Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 57,886

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock, granted pursuant to the Company's 2019 Incentive Plan. The Restricted Stock Units vest and become available as follows: twenty five (25%) percent on each anniversary of the date of grant through the fourth anniversary date of the grant.

F2 · price: Each Restricted Stock Unit was received as a grant on January 6, 2022, for no consideration.

SEC source: 0001140361-22-000963 · form4.xml · nonDerivative · entry 1

Adsett Roger · CIK 0001685904 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 107,179

F1 · kind: Shares sold to satisfy withholding tax obligations upon the vesting of restricted stock units and to cover related broker fees.

SEC source: 0001140361-22-000959 · form4.xml · nonDerivative · entry 1

Flammer Martina M.D. · CIK 0001796960 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,345

F1 · kind: Shares sold to satisfy withholding tax obligations upon the vesting of restricted stock units and to cover related broker fees

SEC source: 0001140361-22-000961 · form4.xml · nonDerivative · entry 1

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 195,093

F1 · kind: Shares sold to satisfy withholding tax obligations upon the vesting of restricted stock units and to cover related broker fees.

SEC source: 0001140361-22-000956 · form4.xml · nonDerivative · entry 1

Schaeffer Orlov S Nicole · CIK 0001401017 · Chief People Strategy Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 50,040

F1 · kind: Shares sold to satisfy withholding tax obligations upon the vesting of restricted stock units and to cover related broker fees.

F2 · balance_after: Includes 29 shares acquired through the Company's 2018 Employee Stock Purchase Plan.

SEC source: 0001140361-22-000953 · form4.xml · nonDerivative · entry 1

Smith Michael Alexander · CIK 0001870278 · General Counsel, Senior VP

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,762

F1 · kind: Shares sold to satisfy withholding tax obligations upon the vesting of restricted stock units and to cover related broker fees.

F2 · balance_after: Includes 283 shares acquired through the Company's 2018 Employee Stock Purchase Plan.

SEC source: 0001140361-21-043222 · form4.xml · derivative · entry 9

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,228

Underlying: Common Stock · 46,614 shares

Expires 2022-10-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: twenty five percent (25%) vested on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001140361-21-043222 · form4.xml · nonDerivative · entry 6

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 202,219

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4 · price: This is the weighted average sales price representing 46,614 shares sold at prices ranging from $27.43 to $28.15 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001140361-21-043222 · form4.xml · nonDerivative · entry 5

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 248,833

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

SEC source: 0001140361-21-043222 · form4.xml · derivative · entry 8

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 76,842

Underlying: Common Stock · 46,614 shares

Expires 2022-10-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: twenty five percent (25%) vested on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001140361-21-043222 · form4.xml · derivative · entry 7

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 3,386 shares

Expires 2022-09-10

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: twenty five percent (25%) vested on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001140361-21-043222 · form4.xml · nonDerivative · entry 4

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 202,219

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · price: This is the weighted average sales price representing 46,614 shares sold at prices ranging from $27.95 to $28.45 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001140361-21-043222 · form4.xml · nonDerivative · entry 3

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 248,833

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

SEC source: 0001140361-21-043222 · form4.xml · nonDerivative · entry 2

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 202,219

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · price: This is the weighted average sales price representing 3,386 shares sold at prices ranging from $28.00 to $28.49 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001140361-21-043222 · form4.xml · nonDerivative · entry 1

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 205,605

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

SEC source: 0001140361-21-039388 · form4.xml · nonDerivative · entry 1

SHAROKY MELVIN MD · CIK 0001182633 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 234,976

F1 · kind: The reported transactions involved a gift of securities by the Reporting Person to each of the following individuals: Jason Wink (son-in-law) and Pilee Sharoky (daughter-in-law), neither of whom share the Reporting Person's household.

SEC source: 0001140361-21-036424 · form4.xml · derivative · entry 5

Schaeffer Orlov S Nicole · CIK 0001401017 · Chief People Strategy Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 25,000 shares

Expires 2023-05-23

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: These options vested and became exercisable with respect to 12,500 shares upon receipt of the first written acceptance of an NDA or MAA filing from an applicable regulatory authority (FDA or EMA); and with respect to the remaining 12,500 shares upon receipt of the first written approval of an NDA or MAA filing from an applicable regulatory authority (FDA or EMA).

SEC source: 0001140361-21-036424 · form4.xml · derivative · entry 4

Schaeffer Orlov S Nicole · CIK 0001401017 · Chief People Strategy Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,000

Underlying: Common Stock · 36,000 shares

Expires 2023-05-23

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: twenty five percent (25%) vested on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001140361-21-036424 · form4.xml · nonDerivative · entry 3

Schaeffer Orlov S Nicole · CIK 0001401017 · Chief People Strategy Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 51,514

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4 · price: This is the weighted average sales price representing 340 shares sold at prices ranging from $31.00 to $31.14 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001140361-21-036424 · form4.xml · nonDerivative · entry 2

Schaeffer Orlov S Nicole · CIK 0001401017 · Chief People Strategy Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 51,854

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · price: This is the weighted average sales price representing 60,660 shares sold at prices ranging from $30.00 to $30.99 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001140361-21-036424 · form4.xml · nonDerivative · entry 1

Schaeffer Orlov S Nicole · CIK 0001401017 · Chief People Strategy Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 112,514

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · balance_after: Includes 722 shares acquired through the Company's 2018 Employee Stock Purchase Plan.

SEC source: 0001140361-21-036422 · form4.xml · nonDerivative · entry 1

Brennan David R · CIK 0001609305 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 80,876

SEC source: 0001140361-21-036421 · form4.xml · nonDerivative · entry 1

ENGELSEN STEINAR J · CIK 0001218860 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 320,802

F1 · price: This is the weighted average sales price representing the shares purchased at prices ranging from $30.05 to $30.25 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares purchased at each price within the price range upon request.

SEC source: 0001140361-21-033275 · form4.xml · derivative · entry 4

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,386

Underlying: Common Stock · 96,614 shares

Expires 2022-09-10

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: twenty five percent (25%) vested on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001140361-21-033275 · form4.xml · nonDerivative · entry 3

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 202,219

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4 · price: This is the weighted average sales price representing 13,307 shares sold at prices ranging from $27.60 to $27.74 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001140361-21-033275 · form4.xml · nonDerivative · entry 2

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 215,526

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · price: This is the weighted average sales price representing 83,307 shares sold at prices ranging from $26.60 to $27.59 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001140361-21-033275 · form4.xml · nonDerivative · entry 1

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 298,833

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · balance_after: Includes 748 shares acquired through the Company's 2018 Employee Stock Purchase Plan.

SEC source: 0001140361-21-030808 · form4.xml · derivative · entry 3

SORIANO JOHN · CIK 0001740947 · Chief Compliance Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 52,046

Underlying: Common Stock · 17,349 shares

Expires 2029-01-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The options become exercisable based on the following vesting schedule: twenty five percent (25%) vested on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001140361-21-030808 · form4.xml · nonDerivative · entry 2

SORIANO JOHN · CIK 0001740947 · Chief Compliance Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 35,204

F1 · price: This is the weighted average sales price representing the shares sold at prices ranging from $28.11 to $28.37 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001140361-21-030808 · form4.xml · nonDerivative · entry 1

SORIANO JOHN · CIK 0001740947 · Chief Compliance Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 52,553

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001140361-21-023940 · form4.xml · derivative · entry 2

Smith Michael Alexander · CIK 0001870278 · General Counsel, Senior VP

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,550

Underlying: Common Stock · 32,550 shares

Expires 2031-07-08

F3 · derivative.exercise_date: In connection with the appointment of Mr. Smith as the Company's General Counsel, Senior Vice President, the Company granted Mr. Smith an option to purchase a total of 32,550 shares of the Company's common stock under the Company's 2019 Incentive Plan. The option becomes exercisable based on the following vesting schedule: twenty-five percent (25%) vest on the first anniversary of the date of grant and twelve and one-half percent (12.5%) vest on each six month anniversary date thereafter through the fourth anniversary of the date of grant, subject to Mr. Smith's continued employment with the Company on each vesting date.

SEC source: 0001140361-21-023940 · form4.xml · nonDerivative · entry 1

Smith Michael Alexander · CIK 0001870278 · General Counsel, Senior VP

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,228

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock, granted pursuant to the Company's 2019 Incentive Plan. The Restricted Stock Units vest and become available as follows: twenty five (25%) percent on each anniversary of the date of grant through the fourth anniversary date of the grant.

F2 · price: Each Restricted Stock Unit was received as a grant on July 8, 2021, for no consideration.