INO

SEC source: 0001055726-19-000014 · wf-form4_155242479641647.xml · nonDerivative · entry 4

KIES PETER · CIK 0001259780 · CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 109,130

F4 · kind: The transaction reported represents the withholding of shares by the issuer to satisfy the reporting person's tax withholding obligations in connection with the vesting and settlement of the restricted stock units award reported in footnote (3) herein.

SEC source: 0001055726-19-000014 · wf-form4_155242479641647.xml · nonDerivative · entry 3

KIES PETER · CIK 0001259780 · CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 116,196

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · price: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 61,300 restricted stock units is as follows: 20,434 shares vested on March 10, 2018; 20,433 shares vested on March 10, 2019; 20,433 shares will vest on March 10, 2020. Vested restricted stock units can be settled in shares of common stock, cash or a combination of both.

SEC source: 0001055726-19-000015 · wf-form4_155242488364573.xml · derivative · entry 11

Kim Jong Joseph · CIK 0001464549 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 105,700

Underlying: Common Stock · 105,700 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 317,100 restricted stock units is as follows: 105,700 shares vested on March 10, 2018; 105,700 shares vested on March 10, 2019; 105,700 shares will vest on March 10, 2020. Vested restricted stock units can be settled in shares of common stock, cash or a combination of both.

F3 · price: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 317,100 restricted stock units is as follows: 105,700 shares vested on March 10, 2018; 105,700 shares vested on March 10, 2019; 105,700 shares will vest on March 10, 2020. Vested restricted stock units can be settled in shares of common stock, cash or a combination of both.

F3 · derivative.exercise_date: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 317,100 restricted stock units is as follows: 105,700 shares vested on March 10, 2018; 105,700 shares vested on March 10, 2019; 105,700 shares will vest on March 10, 2020. Vested restricted stock units can be settled in shares of common stock, cash or a combination of both.

F3 · derivative.expiration_date: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 317,100 restricted stock units is as follows: 105,700 shares vested on March 10, 2018; 105,700 shares vested on March 10, 2019; 105,700 shares will vest on March 10, 2020. Vested restricted stock units can be settled in shares of common stock, cash or a combination of both.

SEC source: 0001055726-19-000015 · wf-form4_155242488364573.xml · nonDerivative · entry 4

Kim Jong Joseph · CIK 0001464549 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,511,055

F4 · kind: The transaction reported represents the withholding of shares by the issuer to satisfy the reporting person's tax withholding obligations in connection with the vesting and settlement of the restricted stock units award reported in footnote (3) herein.

SEC source: 0001055726-19-000015 · wf-form4_155242488364573.xml · nonDerivative · entry 3

Kim Jong Joseph · CIK 0001464549 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,541,159

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · price: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 317,100 restricted stock units is as follows: 105,700 shares vested on March 10, 2018; 105,700 shares vested on March 10, 2019; 105,700 shares will vest on March 10, 2020. Vested restricted stock units can be settled in shares of common stock, cash or a combination of both.

SEC source: 0001055726-19-000013 · wf-form4_155242471665422.xml · derivative · entry 6

Weiner David B. · CIK 0001669080 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,666

Underlying: Common Stock · 11,667 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 35,000 restricted stock units is as follows: 11,667 shares vested on March 10, 2018; 11,667 shares vested on March 10, 2019; 11,666 shares will vest on March 10, 2020. Vested restricted stock units can be settled in shares of common stock, cash or a combination of both.

F3 · price: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 35,000 restricted stock units is as follows: 11,667 shares vested on March 10, 2018; 11,667 shares vested on March 10, 2019; 11,666 shares will vest on March 10, 2020. Vested restricted stock units can be settled in shares of common stock, cash or a combination of both.

F3 · derivative.exercise_date: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 35,000 restricted stock units is as follows: 11,667 shares vested on March 10, 2018; 11,667 shares vested on March 10, 2019; 11,666 shares will vest on March 10, 2020. Vested restricted stock units can be settled in shares of common stock, cash or a combination of both.

F3 · derivative.expiration_date: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 35,000 restricted stock units is as follows: 11,667 shares vested on March 10, 2018; 11,667 shares vested on March 10, 2019; 11,666 shares will vest on March 10, 2020. Vested restricted stock units can be settled in shares of common stock, cash or a combination of both.

SEC source: 0001055726-19-000013 · wf-form4_155242471665422.xml · nonDerivative · entry 3

Weiner David B. · CIK 0001669080 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 805,292

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · price: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 35,000 restricted stock units is as follows: 11,667 shares vested on March 10, 2018; 11,667 shares vested on March 10, 2019; 11,666 shares will vest on March 10, 2020. Vested restricted stock units can be settled in shares of common stock, cash or a combination of both.

SEC source: 0001055726-19-000018 · wf-form4_155243280950585.xml · derivative · entry 5

Humeau Laurent · CIK 0001770390 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 2,666 shares

Expires 2029-03-08

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of common stock. The 2,666 restricted stock units vested on March 9, 2019.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock. The 2,666 restricted stock units vested on March 9, 2019.

F1 · derivative.exercise_date: Each restricted stock unit represents a contingent right to receive one share of common stock. The 2,666 restricted stock units vested on March 9, 2019.

F1 · derivative.expiration_date: Each restricted stock unit represents a contingent right to receive one share of common stock. The 2,666 restricted stock units vested on March 9, 2019.

SEC source: 0001055726-19-000018 · wf-form4_155243280950585.xml · nonDerivative · entry 2

Humeau Laurent · CIK 0001770390 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,969

F2 · kind: The transaction reported represents the withholding of shares by the issuer to satisfy the reporting person's tax withholding obligations in connection with the vesting and settlement of the restricted stock unit award reported in footnote (1) herein.

SEC source: 0001055726-19-000018 · wf-form4_155243280950585.xml · nonDerivative · entry 1

Humeau Laurent · CIK 0001770390 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,867

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock. The 2,666 restricted stock units vested on March 9, 2019.

SEC source: 0001055726-19-000014 · wf-form4_155242479641647.xml · derivative · entry 6

KIES PETER · CIK 0001259780 · CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 25,000 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 75,000 restricted stock units was as follows: 25,000 shares vested on March 9, 2017; 25,000 shares vested on March 9, 2018; 25,000 shares vested on March 9, 2019.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 75,000 restricted stock units was as follows: 25,000 shares vested on March 9, 2017; 25,000 shares vested on March 9, 2018; 25,000 shares vested on March 9, 2019.

F1 · derivative.exercise_date: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 75,000 restricted stock units was as follows: 25,000 shares vested on March 9, 2017; 25,000 shares vested on March 9, 2018; 25,000 shares vested on March 9, 2019.

F1 · derivative.expiration_date: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 75,000 restricted stock units was as follows: 25,000 shares vested on March 9, 2017; 25,000 shares vested on March 9, 2018; 25,000 shares vested on March 9, 2019.

SEC source: 0001055726-19-000014 · wf-form4_155242479641647.xml · nonDerivative · entry 2

KIES PETER · CIK 0001259780 · CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 95,763

F2 · kind: The transaction reported represents the withholding of shares by the issuer to satisfy the reporting person's tax withholding obligations in connection with the vesting and settlement of the restricted stock units award reported in footnote (1) herein.

SEC source: 0001055726-19-000014 · wf-form4_155242479641647.xml · nonDerivative · entry 1

KIES PETER · CIK 0001259780 · CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 104,354

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 75,000 restricted stock units was as follows: 25,000 shares vested on March 9, 2017; 25,000 shares vested on March 9, 2018; 25,000 shares vested on March 9, 2019.

SEC source: 0001055726-19-000015 · wf-form4_155242488364573.xml · derivative · entry 10

Kim Jong Joseph · CIK 0001464549 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 57,333 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 172,000 restricted stock units was as follows: 57,334 shares vested on March 9, 2017; 57,333 shares vested on March 9, 2018; 57,333 shares vested on March 9, 2019.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 172,000 restricted stock units was as follows: 57,334 shares vested on March 9, 2017; 57,333 shares vested on March 9, 2018; 57,333 shares vested on March 9, 2019.

F1 · derivative.exercise_date: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 172,000 restricted stock units was as follows: 57,334 shares vested on March 9, 2017; 57,333 shares vested on March 9, 2018; 57,333 shares vested on March 9, 2019.

F1 · derivative.expiration_date: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 172,000 restricted stock units was as follows: 57,334 shares vested on March 9, 2017; 57,333 shares vested on March 9, 2018; 57,333 shares vested on March 9, 2019.

SEC source: 0001055726-19-000015 · wf-form4_155242488364573.xml · nonDerivative · entry 2

Kim Jong Joseph · CIK 0001464549 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,435,459

F2 · kind: The transaction reported represents the withholding of shares by the issuer to satisfy the reporting person's tax withholding obligations in connection with the vesting and settlement of the restricted stock units award reported in footnote (1) herein.

SEC source: 0001055726-19-000015 · wf-form4_155242488364573.xml · nonDerivative · entry 1

Kim Jong Joseph · CIK 0001464549 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,451,788

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 172,000 restricted stock units was as follows: 57,334 shares vested on March 9, 2017; 57,333 shares vested on March 9, 2018; 57,333 shares vested on March 9, 2019.

SEC source: 0001055726-19-000013 · wf-form4_155242471665422.xml · derivative · entry 5

Weiner David B. · CIK 0001669080 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 10,000 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 30,000 restricted stock units is as follows: 10,000 shares vested on March 9, 2017; 10,000 shares vested on March 9, 2018; 10,000 shares vested on March 9, 2019.

F2 · price: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 30,000 restricted stock units is as follows: 10,000 shares vested on March 9, 2017; 10,000 shares vested on March 9, 2018; 10,000 shares vested on March 9, 2019.

F2 · derivative.exercise_date: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 30,000 restricted stock units is as follows: 10,000 shares vested on March 9, 2017; 10,000 shares vested on March 9, 2018; 10,000 shares vested on March 9, 2019.

F2 · derivative.expiration_date: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 30,000 restricted stock units is as follows: 10,000 shares vested on March 9, 2017; 10,000 shares vested on March 9, 2018; 10,000 shares vested on March 9, 2019.

SEC source: 0001055726-19-000013 · wf-form4_155242471665422.xml · derivative · entry 4

Weiner David B. · CIK 0001669080 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 5,333 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 16,000 restricted stock units was as follows: 5,334 shares vested on March 9, 2017; 5,333 shares vested on March 9, 2018; 5,333 shares vested on March 9, 2019.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 16,000 restricted stock units was as follows: 5,334 shares vested on March 9, 2017; 5,333 shares vested on March 9, 2018; 5,333 shares vested on March 9, 2019.

F1 · derivative.exercise_date: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 16,000 restricted stock units was as follows: 5,334 shares vested on March 9, 2017; 5,333 shares vested on March 9, 2018; 5,333 shares vested on March 9, 2019.

F1 · derivative.expiration_date: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 16,000 restricted stock units was as follows: 5,334 shares vested on March 9, 2017; 5,333 shares vested on March 9, 2018; 5,333 shares vested on March 9, 2019.

SEC source: 0001055726-19-000013 · wf-form4_155242471665422.xml · nonDerivative · entry 2

Weiner David B. · CIK 0001669080 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 793,625

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · price: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 30,000 restricted stock units is as follows: 10,000 shares vested on March 9, 2017; 10,000 shares vested on March 9, 2018; 10,000 shares vested on March 9, 2019.

SEC source: 0001055726-19-000013 · wf-form4_155242471665422.xml · nonDerivative · entry 1

Weiner David B. · CIK 0001669080 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 783,625

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 16,000 restricted stock units was as follows: 5,334 shares vested on March 9, 2017; 5,333 shares vested on March 9, 2018; 5,333 shares vested on March 9, 2019.

SEC source: 0001055726-19-000018 · wf-form4_155243280950585.xml · derivative · entry 8

Humeau Laurent · CIK 0001770390 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 59,700

Underlying: Common Stock · 59,700 shares

Expires 2029-03-08

F6 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 59,700 restricted stock units is as follows: 19,900 shares will vest on March 8, 2020; 19,900 shares will vest on March 8, 2021; 19,900 shares will vest on March 10, 2022. Vested restricted stock units can be settled in shares of common stock, cash or a combination of both.

F6 · derivative.exercise_date: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 59,700 restricted stock units is as follows: 19,900 shares will vest on March 8, 2020; 19,900 shares will vest on March 8, 2021; 19,900 shares will vest on March 10, 2022. Vested restricted stock units can be settled in shares of common stock, cash or a combination of both.

F6 · derivative.expiration_date: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 59,700 restricted stock units is as follows: 19,900 shares will vest on March 8, 2020; 19,900 shares will vest on March 8, 2021; 19,900 shares will vest on March 10, 2022. Vested restricted stock units can be settled in shares of common stock, cash or a combination of both.

SEC source: 0001055726-19-000018 · wf-form4_155243280950585.xml · derivative · entry 7

Humeau Laurent · CIK 0001770390 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 93,200

Underlying: Common Stock · 93,200 shares

Expires 2029-03-08

F5 · derivative.exercise_date: The vesting schedule for the 93,200 options is as follows: 23,300 shares vested on March 8, 2019; 23,300 shares will vest on March 8, 2020; 23,300 shares will vest on March 8, 2021; 23,300 shares will vest on March 8, 2022.

SEC source: 0001055726-19-000014 · wf-form4_155242479641647.xml · derivative · entry 9

KIES PETER · CIK 0001259780 · CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 64,400

Underlying: Common Stock · 64,400 shares

Expires not disclosed

F6 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 64,400 restricted stock units is as follows: 21,467 shares will vest on March 8, 2020; 21,467 shares will vest on March 8, 2021; 21,466 shares will vest on March 8, 2022.Vested restricted stock units can be settled in shares of common stock, cash or a combination of both.

F6 · derivative.exercise_date: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 64,400 restricted stock units is as follows: 21,467 shares will vest on March 8, 2020; 21,467 shares will vest on March 8, 2021; 21,466 shares will vest on March 8, 2022.Vested restricted stock units can be settled in shares of common stock, cash or a combination of both.

F6 · derivative.expiration_date: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 64,400 restricted stock units is as follows: 21,467 shares will vest on March 8, 2020; 21,467 shares will vest on March 8, 2021; 21,466 shares will vest on March 8, 2022.Vested restricted stock units can be settled in shares of common stock, cash or a combination of both.

SEC source: 0001055726-19-000014 · wf-form4_155242479641647.xml · derivative · entry 8

KIES PETER · CIK 0001259780 · CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 100,500

Underlying: Common Stock · 100,500 shares

Expires 2029-03-08

F5 · derivative.exercise_date: The vesting schedule for the 100,500 options is as follows: 25,125 shares vested on March 8, 2019; 25,125 shares will vest on March 8, 2020; 25,125 shares will vest on March 8, 2021; 25,125 shares will vest on March 8, 2022.

SEC source: 0001055726-19-000015 · wf-form4_155242488364573.xml · derivative · entry 13

Kim Jong Joseph · CIK 0001464549 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 191,100

Underlying: Common Stock · 191,100 shares

Expires not disclosed

F6 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 191,100 restricted stock units is as follows: 63,700 shares will vest on March 8, 2020; 63,700 shares will vest on March 8, 2021; 63,700 shares will vest on March 8, 2022.Vested restricted stock units can be settled in shares of common stock, cash or a combination of both.

F6 · derivative.exercise_date: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 191,100 restricted stock units is as follows: 63,700 shares will vest on March 8, 2020; 63,700 shares will vest on March 8, 2021; 63,700 shares will vest on March 8, 2022.Vested restricted stock units can be settled in shares of common stock, cash or a combination of both.

F6 · derivative.expiration_date: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 191,100 restricted stock units is as follows: 63,700 shares will vest on March 8, 2020; 63,700 shares will vest on March 8, 2021; 63,700 shares will vest on March 8, 2022.Vested restricted stock units can be settled in shares of common stock, cash or a combination of both.

SEC source: 0001055726-19-000015 · wf-form4_155242488364573.xml · derivative · entry 12

Kim Jong Joseph · CIK 0001464549 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 298,100

Underlying: Common Stock · 298,100 shares

Expires 2029-03-08

F5 · derivative.exercise_date: The vesting schedule for the 298,100 options is as follows: 74,525 shares vested on March 8, 2019; 74,525 shares will vest on March 8, 2020; 74,525 shares will vest on March 8, 2021; 74,525 shares will vest on March 8, 2022.

SEC source: 0001055726-19-000013 · wf-form4_155242471665422.xml · derivative · entry 8

Weiner David B. · CIK 0001669080 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 35,000

Underlying: Common Stock · 35,000 shares

Expires not disclosed

F5 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 35,000 restricted stock units is as follows: 11,667 shares will vest on March 8, 2020; 11,667 shares will vest on March 8, 2021; 11,666 shares will vest on March 8, 2022. Vested restricted stock units can be settled in shares of common stock, cash or a combination of both.

F5 · derivative.exercise_date: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 35,000 restricted stock units is as follows: 11,667 shares will vest on March 8, 2020; 11,667 shares will vest on March 8, 2021; 11,666 shares will vest on March 8, 2022. Vested restricted stock units can be settled in shares of common stock, cash or a combination of both.

F5 · derivative.expiration_date: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 35,000 restricted stock units is as follows: 11,667 shares will vest on March 8, 2020; 11,667 shares will vest on March 8, 2021; 11,666 shares will vest on March 8, 2022. Vested restricted stock units can be settled in shares of common stock, cash or a combination of both.

SEC source: 0001055726-19-000013 · wf-form4_155242471665422.xml · derivative · entry 7

Weiner David B. · CIK 0001669080 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 60,000

Underlying: Common Stock · 60,000 shares

Expires 2029-03-08

F4 · derivative.exercise_date: The vesting schedule for the 60,000 options is as follows: 15,000 shares vested on March 8, 2019; 15,000 shares will vest on March 8, 2020; 15,000 shares will vest on March 8, 2021; 15,000 shares will vest on March 8, 2022.

SEC source: 0001055726-19-000009 · wf-form4_155199673994793.xml · derivative · entry 3

Bagarazzi Mark · CIK 0001539067 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 55,133

Underlying: Common Stock · 27,567 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 82,700 restricted stock units is as follows: 27,567 shares vested on March 5, 2019; 27,567 shares will vest on March 5, 2020; 27,566 shares will vest on March 5, 2021. Vested units of restricted stock can be settled in shares of common stock, cash or a combination of both.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 82,700 restricted stock units is as follows: 27,567 shares vested on March 5, 2019; 27,567 shares will vest on March 5, 2020; 27,566 shares will vest on March 5, 2021. Vested units of restricted stock can be settled in shares of common stock, cash or a combination of both.

F1 · derivative.exercise_date: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 82,700 restricted stock units is as follows: 27,567 shares vested on March 5, 2019; 27,567 shares will vest on March 5, 2020; 27,566 shares will vest on March 5, 2021. Vested units of restricted stock can be settled in shares of common stock, cash or a combination of both.

F1 · derivative.expiration_date: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 82,700 restricted stock units is as follows: 27,567 shares vested on March 5, 2019; 27,567 shares will vest on March 5, 2020; 27,566 shares will vest on March 5, 2021. Vested units of restricted stock can be settled in shares of common stock, cash or a combination of both.

SEC source: 0001055726-19-000009 · wf-form4_155199673994793.xml · nonDerivative · entry 2

Bagarazzi Mark · CIK 0001539067 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 100,672

F2 · kind: The transaction reported represents the withholding of shares by the issuer to satisfy the reporting person's tax withholding obligations in connection with the vesting and settlement of the restricted stock units being reported in this Form 4.

SEC source: 0001055726-19-000009 · wf-form4_155199673994793.xml · nonDerivative · entry 1

Bagarazzi Mark · CIK 0001539067 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 109,080

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 82,700 restricted stock units is as follows: 27,567 shares vested on March 5, 2019; 27,567 shares will vest on March 5, 2020; 27,566 shares will vest on March 5, 2021. Vested units of restricted stock can be settled in shares of common stock, cash or a combination of both.

SEC source: 0001055726-19-000008 · wf-form4_155199665711432.xml · derivative · entry 2

Weiner David B. · CIK 0001669080 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,333

Underlying: Common Stock · 11,667 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 35,000 restricted stock units is as follows: 11,667 shares vested on March 5, 2019; 11,667 shares will vest on March 5, 2020; 11,666 shares will vest on March 5, 2021. Vested units of restricted stock can be settled in shares of common stock, cash or a combination of both.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 35,000 restricted stock units is as follows: 11,667 shares vested on March 5, 2019; 11,667 shares will vest on March 5, 2020; 11,666 shares will vest on March 5, 2021. Vested units of restricted stock can be settled in shares of common stock, cash or a combination of both.

F1 · derivative.exercise_date: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 35,000 restricted stock units is as follows: 11,667 shares vested on March 5, 2019; 11,667 shares will vest on March 5, 2020; 11,666 shares will vest on March 5, 2021. Vested units of restricted stock can be settled in shares of common stock, cash or a combination of both.

F1 · derivative.expiration_date: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 35,000 restricted stock units is as follows: 11,667 shares vested on March 5, 2019; 11,667 shares will vest on March 5, 2020; 11,666 shares will vest on March 5, 2021. Vested units of restricted stock can be settled in shares of common stock, cash or a combination of both.

SEC source: 0001055726-19-000008 · wf-form4_155199665711432.xml · nonDerivative · entry 1

Weiner David B. · CIK 0001669080 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 778,292

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 35,000 restricted stock units is as follows: 11,667 shares vested on March 5, 2019; 11,667 shares will vest on March 5, 2020; 11,666 shares will vest on March 5, 2021. Vested units of restricted stock can be settled in shares of common stock, cash or a combination of both.

SEC source: 0001055726-19-000006 · wf-form4_155199640506740.xml · derivative · entry 4

KIES PETER · CIK 0001259780 · CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 55,133

Underlying: Common Stock · 27,567 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 82,700 restricted stock units is as follows: 27,567 shares vested on March 5, 2019; 27,567 shares will vest on March 5, 2020; 27,566 shares will vest on March 5, 2021. Vested units of restricted stock can be settled in shares of common stock, cash or a combination of both.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 82,700 restricted stock units is as follows: 27,567 shares vested on March 5, 2019; 27,567 shares will vest on March 5, 2020; 27,566 shares will vest on March 5, 2021. Vested units of restricted stock can be settled in shares of common stock, cash or a combination of both.

F1 · derivative.exercise_date: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 82,700 restricted stock units is as follows: 27,567 shares vested on March 5, 2019; 27,567 shares will vest on March 5, 2020; 27,566 shares will vest on March 5, 2021. Vested units of restricted stock can be settled in shares of common stock, cash or a combination of both.

F1 · derivative.expiration_date: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 82,700 restricted stock units is as follows: 27,567 shares vested on March 5, 2019; 27,567 shares will vest on March 5, 2020; 27,566 shares will vest on March 5, 2021. Vested units of restricted stock can be settled in shares of common stock, cash or a combination of both.

SEC source: 0001055726-19-000006 · wf-form4_155199640506740.xml · nonDerivative · entry 2

KIES PETER · CIK 0001259780 · CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 79,354

F2 · kind: The transaction reported represents the withholding of shares by the issuer to satisfy the reporting person's tax withholding obligations in connection with the vesting and settlement of the restricted stock units being report in this Form 4.

SEC source: 0001055726-19-000006 · wf-form4_155199640506740.xml · nonDerivative · entry 1

KIES PETER · CIK 0001259780 · CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 89,655

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 82,700 restricted stock units is as follows: 27,567 shares vested on March 5, 2019; 27,567 shares will vest on March 5, 2020; 27,566 shares will vest on March 5, 2021. Vested units of restricted stock can be settled in shares of common stock, cash or a combination of both.

SEC source: 0001055726-19-000007 · wf-form4_155199657903918.xml · derivative · entry 8

Kim Jong Joseph · CIK 0001464549 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 240,200

Underlying: Common Stock · 120,100 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 360,300 restricted stock units is as follows: 120,100 shares vested on March 5, 2019; 120,100 shares will vest on March 5, 2020; 120,100 shares will vest on March 5, 2021. Vested units of restricted stock can be settled in shares of common stock, cash or a combination of both.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 360,300 restricted stock units is as follows: 120,100 shares vested on March 5, 2019; 120,100 shares will vest on March 5, 2020; 120,100 shares will vest on March 5, 2021. Vested units of restricted stock can be settled in shares of common stock, cash or a combination of both.

F1 · derivative.exercise_date: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 360,300 restricted stock units is as follows: 120,100 shares vested on March 5, 2019; 120,100 shares will vest on March 5, 2020; 120,100 shares will vest on March 5, 2021. Vested units of restricted stock can be settled in shares of common stock, cash or a combination of both.

F1 · derivative.expiration_date: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 360,300 restricted stock units is as follows: 120,100 shares vested on March 5, 2019; 120,100 shares will vest on March 5, 2020; 120,100 shares will vest on March 5, 2021. Vested units of restricted stock can be settled in shares of common stock, cash or a combination of both.

SEC source: 0001055726-19-000007 · wf-form4_155199657903918.xml · nonDerivative · entry 2

Kim Jong Joseph · CIK 0001464549 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,394,455

F2 · kind: The transaction reported represents the withholding of shares by the issuer to satisfy the reporting person's tax withholding obligations in connection with the vesting and settlement of the restricted stock units being reported in this Form 4.

SEC source: 0001055726-19-000007 · wf-form4_155199657903918.xml · nonDerivative · entry 1

Kim Jong Joseph · CIK 0001464549 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,428,594

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 360,300 restricted stock units is as follows: 120,100 shares vested on March 5, 2019; 120,100 shares will vest on March 5, 2020; 120,100 shares will vest on March 5, 2021. Vested units of restricted stock can be settled in shares of common stock, cash or a combination of both.

SEC source: 0001055726-19-000004 · wf-form4_154663758186763.xml · derivative · entry 2

Zoth Lota S. · CIK 0001278219 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,270

Underlying: Common Stock · 12,270 shares

Expires not disclosed

F3 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 12,270 restricted stock units is as follows: 4,090 shares will vest on January 3, 2020; 4,090 shares will vest on January 3, 2021; 4,090 shares will vest on January 3, 2022. Vested units of restricted stock can be settled in shares of common stock, cash or a combination of both.

F1 · shares: This grant was made pursuant to the issuer's non-employee director compensation policy.

F3 · derivative.exercise_date: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 12,270 restricted stock units is as follows: 4,090 shares will vest on January 3, 2020; 4,090 shares will vest on January 3, 2021; 4,090 shares will vest on January 3, 2022. Vested units of restricted stock can be settled in shares of common stock, cash or a combination of both.

F3 · derivative.expiration_date: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 12,270 restricted stock units is as follows: 4,090 shares will vest on January 3, 2020; 4,090 shares will vest on January 3, 2021; 4,090 shares will vest on January 3, 2022. Vested units of restricted stock can be settled in shares of common stock, cash or a combination of both.

SEC source: 0001055726-19-000004 · wf-form4_154663758186763.xml · derivative · entry 1

Zoth Lota S. · CIK 0001278219 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,000

Underlying: Common Stock · 20,000 shares

Expires 2029-01-03

F1 · shares: This grant was made pursuant to the issuer's non-employee director compensation policy.

F2 · derivative.exercise_date: The vesting schedule for the 20,000 options is as follows: 5,000 shares vested on January 3, 2019; 5,000 shares will vest on January 3, 2020; 5,000 shares will vest on January 3, 2021; 5,000 shares will vest on January 3, 2022.

SEC source: 0001055726-18-000049 · wf-form4_154413462054861.xml · derivative · entry 2

DHILLON AVTAR S · CIK 0001260933 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 25,000 shares

Expires 2018-12-09

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Gives effect to a 1-for-4 reverse stock split effected by the Issuer on June 5, 2014.

F1 · shares: Gives effect to a 1-for-4 reverse stock split effected by the Issuer on June 5, 2014.

F2 · derivative.exercise_date: The shares underlying this option vested and became exercisable on various dates between December 9, 2008 and December 9, 2011.

F1 · derivative.underlying_shares: Gives effect to a 1-for-4 reverse stock split effected by the Issuer on June 5, 2014.

SEC source: 0001055726-18-000049 · wf-form4_154413462054861.xml · nonDerivative · entry 1

DHILLON AVTAR S · CIK 0001260933 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 106,002

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001055726-18-000048 · wf-form4_154413452889176.xml · derivative · entry 2

YARNO WENDY L · CIK 0001181186 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,180

Underlying: Common Stock · 4,090 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 12,270 restricted stock units is as follows: 4,090 shares vested on December 5, 2018; 4,090 shares will vest on December 5, 2019; 4,090 shares will vest on December 5, 2020. Vested restricted stock units can be settled in shares of common stock, cash or a combination of both.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 12,270 restricted stock units is as follows: 4,090 shares vested on December 5, 2018; 4,090 shares will vest on December 5, 2019; 4,090 shares will vest on December 5, 2020. Vested restricted stock units can be settled in shares of common stock, cash or a combination of both.

F1 · derivative.exercise_date: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 12,270 restricted stock units is as follows: 4,090 shares vested on December 5, 2018; 4,090 shares will vest on December 5, 2019; 4,090 shares will vest on December 5, 2020. Vested restricted stock units can be settled in shares of common stock, cash or a combination of both.

F1 · derivative.expiration_date: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 12,270 restricted stock units is as follows: 4,090 shares vested on December 5, 2018; 4,090 shares will vest on December 5, 2019; 4,090 shares will vest on December 5, 2020. Vested restricted stock units can be settled in shares of common stock, cash or a combination of both.

SEC source: 0001055726-18-000048 · wf-form4_154413452889176.xml · nonDerivative · entry 1

YARNO WENDY L · CIK 0001181186 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,090

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 12,270 restricted stock units is as follows: 4,090 shares vested on December 5, 2018; 4,090 shares will vest on December 5, 2019; 4,090 shares will vest on December 5, 2020. Vested restricted stock units can be settled in shares of common stock, cash or a combination of both.

SEC source: 0001055726-18-000047 · wf-form4_154361682936650.xml · derivative · entry 4

KIES PETER · CIK 0001259780 · CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 10,001 shares

Expires 2018-12-09

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Gives effect to a 1-for-4 reverse stock split effected by the Issuer on June 5, 2014.

F2 · shares: Gives effect to a 1-for-4 reverse stock split effected by the Issuer on June 5, 2014.

F3 · derivative.exercise_date: The shares underlying this option vested and became exercisable on various dates between December 9, 2008 and December 9, 2011.

F2 · derivative.underlying_shares: Gives effect to a 1-for-4 reverse stock split effected by the Issuer on June 5, 2014.

SEC source: 0001055726-18-000047 · wf-form4_154361682936650.xml · nonDerivative · entry 2

KIES PETER · CIK 0001259780 · CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 62,088

F1 · price: The price reported in Column 4 is a weighted average price.

SEC source: 0001055726-18-000047 · wf-form4_154361682936650.xml · nonDerivative · entry 1

KIES PETER · CIK 0001259780 · CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 72,089

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001055726-18-000042 · wf-form4_153695955718652.xml · derivative · entry 8

Kim Jong Joseph · CIK 0001464549 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 49,060 shares

Expires 2018-09-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001055726-18-000042 · wf-form4_153695955718652.xml · nonDerivative · entry 2

Kim Jong Joseph · CIK 0001464549 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,308,494

F1 · price: This transaction was executed in multiple trades at prices ranging from $5.32 to $5.44, inclusive. The price reported in Column 4 is a weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the transactions were effected.