GRAL

SEC source: 0001699031-25-000008 · wk-form4_1738707584.xml · nonDerivative · entry 1

RAGUSA ROBERT P · CIK 0001222644 · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 837,281

F1 · shares: Represents an award of 224,620 restricted stock units ("RSUs") which will vest in three substantially equal annual installments, beginning on February 28, 2026, subject to the awardee's continued service through such date. Each RSU represents the right to receive, at settlement, one share of common stock. The RSUs will be settled in common stock upon vesting.

SEC source: 0001699031-25-000010 · wk-form4_1738707657.xml · nonDerivative · entry 1

Ofman Joshua J. · CIK 0001822088 · President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 562,307

F1 · shares: Represents an award of 110,770 restricted stock units ("RSUs") which will vest in three substantially equal annual installments, beginning on February 28, 2026, subject to the awardee's continued service through such date. Each RSU represents the right to receive, at settlement, one share of common stock. The RSUs will be settled in common stock upon vesting.

SEC source: 0001628280-25-001744 · wk-form4_1737064307.xml · nonDerivative · entry 1

SUMME GREGORY L · CIK 0001143422 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 30,250

F1 · shares: Represents 1,828 deferred stock units granted to Mr. Summe under our deferred stock program and 2024 Equity Incentive Plan in lieu of $32,136.99 of cash fees payable to Mr. Summe for his service as a director, based on a price per share of $17.58, which was the closing price per share of the Company's common stock on January 15, 2025. The awards will vest immediately upon grant date.

SEC source: 0001628280-25-001746 · wk-form4_1737064416.xml · nonDerivative · entry 1

CHASE WILLIAM J · CIK 0001563572 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 28,916

F1 · shares: Represents 1,182 deferred stock units granted to Mr. Chase under our deferred stock program and 2024 Equity Incentive Plan in lieu of $20,794.52 of cash fees payable to Mr. Chase for his service as a director, based on a price per share of $17.58, which was the closing price per share of the Company's common stock on January 15, 2025. The awards will vest immediately upon grant date.

SEC source: 0001628280-25-001745 · wk-form4_1737064352.xml · nonDerivative · entry 1

MIZELL STEVEN · CIK 0001189403 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 28,843

F1 · shares: Represents 1,147 deferred stock units granted to Mr. Mizell under our deferred stock program and 2024 Equity Incentive Plan in lieu of $20,164.38 of cash fees payable to Mr. Mizell for his service as a director, based on a price per share of $17.58, which was the closing price per share of the Company's common stock on January 15, 2025. The awards will vest immediately upon grant date.

SEC source: 0001628280-24-048416 · wk-form4_1732050366.xml · nonDerivative · entry 1

Freidin Aaron · CIK 0002024196 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 268,277

F1 · price: The price reported in Column 4 is a weighted average price calculated by the broker executing the sell-to-cover transactions. These shares were sold as part of a block trade in multiple transactions, and the Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate sales price.

SEC source: 0001628280-24-045324 · wk-form4_1730841833.xml · derivative · entry 1

Ofman Joshua J. · CIK 0001822088 · President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 63,484

Underlying: Common Stock · 63,484 shares

Expires 2030-03-05

F1 · derivative.exercise_date: Represents an option to purchase 63,484 shares of common stock that was originally granted on March 6, 2020 and for which the performance condition was determined to be met on November 1, 2024. The option will vest and become exercisable in thirty-six substantially equal monthly installments, beginning December 1, 2024.

F1 · balance_after: Represents an option to purchase 63,484 shares of common stock that was originally granted on March 6, 2020 and for which the performance condition was determined to be met on November 1, 2024. The option will vest and become exercisable in thirty-six substantially equal monthly installments, beginning December 1, 2024.

SEC source: 0001628280-24-044796 · wk-form4_1730499373.xml · nonDerivative · entry 1

SUMME GREGORY L · CIK 0001143422 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 28,422

F1 · shares: Represents 296 deferred stock units granted to Mr. Summe under our deferred stock program and 2024 Equity Incentive Plan in lieu of $4,041.10 of cash fees payable to Mr. Summe for his service as a director, based on a price per share of $13.62, which was the closing price per share of the Company's common stock on October 30, 2024. The awards will vest immediately upon grant date.

SEC source: 0001628280-24-044798 · wk-form4_1730499426.xml · nonDerivative · entry 1

CHASE WILLIAM J · CIK 0001563572 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,734

F1 · shares: Represents 210 deferred stock units granted to Mr. Chase under our deferred stock program and 2024 Equity Incentive Plan in lieu of $2,863.01 of cash fees payable to Mr. Chase for his service as a director, based on a price per share of $13.62, which was the closing price per share of the Company's common stock on October 30, 2024. The awards will vest immediately upon grant date.

SEC source: 0001628280-24-044797 · wk-form4_1730499396.xml · nonDerivative · entry 1

MIZELL STEVEN · CIK 0001189403 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,696

F1 · price: Represents 248 deferred stock units granted to Mr. Mizell under our deferred stock program and 2024 Equity Incentive Plan in lieu of $3,383.56 of cash fees payable to Mr. Mizell for his service as a director, based on a price per share of $13.62, which was the closing price per share of the Company's common stock on October 30, 2024. The awards will vest immediately upon grant date.

SEC source: 0001628280-24-044799 · wk-form4_1730499447.xml · nonDerivative · entry 1

Krevans Sarah · CIK 0002041931 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 31,055

F1 · shares: Represents an award of 31,055 restricted stock units ("RSUs") which will vest and become payable in three substantially equal annual installments beginning on October 21, 2025, subject to full accelerated vesting upon a change in control of the Issuer. Each RSU represents the right to receive, at settlement, one share of common stock. The RSUs will be settled in common stock upon vesting.

SEC source: 0001628280-24-043072 · wk-form4_1729204454.xml · nonDerivative · entry 1

SUMME GREGORY L · CIK 0001143422 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 28,126

F1 · shares: Represents 1,656 deferred stock units granted to Mr. Summe under our deferred stock program and 2024 Equity Incentive Plan in lieu of $23,205.48 of cash fees payable to Mr. Summe for his service as a director, based on a price per share of $14.01, which was the closing price per share of the Company's common stock on October 15, 2024. The awards will vest immediately upon grant date.

SEC source: 0001628280-24-043071 · wk-form4_1729204421.xml · nonDerivative · entry 1

CHASE WILLIAM J · CIK 0001563572 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,524

F1 · shares: Represents 1,054 deferred stock units granted to Mr. Chase under our deferred stock program and 2024 Equity Incentive Plan in lieu of $14,767.12 of cash fees payable to Mr. Chase for his service as a director, based on a price per share of $14.01, which was the closing price per share of the Company's common stock on October 15, 2024. The awards will vest immediately upon grant date.

SEC source: 0001628280-24-043069 · wk-form4_1729204370.xml · nonDerivative · entry 1

RAGUSA ROBERT P · CIK 0001222644 · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 612,661

F1 · price: The price reported in Column 4 is a weighted average price calculated by the broker executing the Sell-To-Cover transactions. These shares were sold as part of a block trade in multiple transactions, and the Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate sales price.

SEC source: 0001628280-24-043073 · wk-form4_1729204505.xml · nonDerivative · entry 1

MIZELL STEVEN · CIK 0001189403 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,448

F1 · shares: Represents 978 deferred stock units granted to Mr. Mizell under our deferred stock program and 2024 Equity Incentive Plan in lieu of $13,712.33 of cash fees payable to Mr. Mizell for his service as a director, based on a price per share of $14.01, which was the closing price per share of the Company's common stock on October 15, 2024. The awards will vest immediately upon grant date.

SEC source: 0000898432-24-000825 · form4.xml · nonDerivative · entry 5

DING CHUN R · CIK 0001250077 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,644,855

F8 · price: On October 9, 2024, the CRCM Funds acquired 16,200 shares of common stock in a series of transactions at prices ranging from $12.73 to $13.14 per share. The price reported in Column 4 is a weighted average price. The detailed breakdown of executed transactions will be furnished upon request.

F1 · ownership.nature: Securities are owned directly by funds (the "CRCM Funds") and separately managed accounts managed by CRCM LP, a Delaware limited partnership and a registered investment adviser with the U.S. Securities and Exchange Commission (the "Investment Manager"). The Reporting Person holds ownership interests in the CRCM Funds. The Reporting Person is the managing partner of the Investment Manager and may be deemed to have an indirect pecuniary interest in a percentage of the securities held by the CRCM Funds. The CRCM Funds and separately managed accounts hold directly in the aggregate 3,644,855 shares of common stock of the Issuer ("common stock"). The Reporting Person may be deemed to beneficially own a percentage of shares of common stock by virtue of his proportional interest in the CRCM Funds.

F2 · ownership.nature: The Reporting Person disclaims any beneficial ownership of any of the Issuer's securities reported herein, or otherwise, except as to securities representing the Reporting Person's proportional interest in the CRCM Funds, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of such other securities of the Issuer for purposes of Section 16 or for any other purpose.

SEC source: 0001628280-24-042469 · wk-form4_1728347666.xml · nonDerivative · entry 2

Freidin Aaron · CIK 0002024196 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 298,729

F2 · shares: Represents an award of 45,840 RSUs which will vest and become payable on October 3, 2026, subject to the awardee's continuing to be a service provider on such date.

SEC source: 0001628280-24-042469 · wk-form4_1728347666.xml · nonDerivative · entry 1

Freidin Aaron · CIK 0002024196 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 252,889

F1 · shares: Represents an award of 79,460 restricted stock units ("RSUs") which will vest and become payable on April 3, 2026, subject to the awardee's continuing to be a service provider on such date. Each RSU represents the right to receive, at settlement, one share of common stock. The RSUs will be settled in common stock upon vesting.

SEC source: 0001628280-24-042471 · wk-form4_1728347776.xml · nonDerivative · entry 2

RAGUSA ROBERT P · CIK 0001222644 · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 736,115

F2 · shares: Represents an award of 45,840 RSUs which will vest and become payable on October 3, 2026, subject to the awardee's continuing to be a service provider on such date.

SEC source: 0001628280-24-042471 · wk-form4_1728347776.xml · nonDerivative · entry 1

RAGUSA ROBERT P · CIK 0001222644 · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 690,275

F1 · shares: Represents an award of 214,240 restricted stock units ("RSUs") which will vest and become payable on April 3, 2026, subject to the awardee's continuing to be a service provider on such date. Each RSU represents the right to receive, at settlement, one share of common stock. The RSUs will be settled in common stock upon vesting.

SEC source: 0001628280-24-042470 · wk-form4_1728347730.xml · nonDerivative · entry 2

Ofman Joshua J. · CIK 0001822088 · President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 451,537

F2 · shares: Represents an award of 152,810 RSUs which will vest and become payable on October 3, 2025, subject to the awardee's continuing to be a service provider on such date.

SEC source: 0001628280-24-042470 · wk-form4_1728347730.xml · nonDerivative · entry 1

Ofman Joshua J. · CIK 0001822088 · President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 298,727

F1 · shares: Represents an award of 106,970 restricted stock units ("RSUs") which will vest and become payable on April 3, 2026, subject to the awardee's continuing to be a service provider on such date. Each RSU represents the right to receive, at settlement, one share of common stock. The RSUs will be settled in common stock upon vesting.

SEC source: 0000898432-24-000825 · form4.xml · nonDerivative · entry 4

DING CHUN R · CIK 0001250077 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,628,655

F6 · kind: The shares of the common stock were contributed by a limited partner of a CRCM Fund to the CRCM Funds as an in-kind subscription for ownership interests in such fund.

F7 · price: Represents the closing price per share of the common stock on the date on which the shares were contributed.

F1 · ownership.nature: Securities are owned directly by funds (the "CRCM Funds") and separately managed accounts managed by CRCM LP, a Delaware limited partnership and a registered investment adviser with the U.S. Securities and Exchange Commission (the "Investment Manager"). The Reporting Person holds ownership interests in the CRCM Funds. The Reporting Person is the managing partner of the Investment Manager and may be deemed to have an indirect pecuniary interest in a percentage of the securities held by the CRCM Funds. The CRCM Funds and separately managed accounts hold directly in the aggregate 3,644,855 shares of common stock of the Issuer ("common stock"). The Reporting Person may be deemed to beneficially own a percentage of shares of common stock by virtue of his proportional interest in the CRCM Funds.

F2 · ownership.nature: The Reporting Person disclaims any beneficial ownership of any of the Issuer's securities reported herein, or otherwise, except as to securities representing the Reporting Person's proportional interest in the CRCM Funds, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of such other securities of the Issuer for purposes of Section 16 or for any other purpose.

SEC source: 0000898432-24-000825 · form4.xml · nonDerivative · entry 3

DING CHUN R · CIK 0001250077 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,558,655

F5 · price: On October 3, 2024, the CRCM Funds acquired 35,000 shares of common stock in a series of transactions at prices ranging from $12.57 to $13.03 per share. The price reported in Column 4 is a weighted average price. The detailed breakdown of executed transactions will be furnished upon request.

F1 · ownership.nature: Securities are owned directly by funds (the "CRCM Funds") and separately managed accounts managed by CRCM LP, a Delaware limited partnership and a registered investment adviser with the U.S. Securities and Exchange Commission (the "Investment Manager"). The Reporting Person holds ownership interests in the CRCM Funds. The Reporting Person is the managing partner of the Investment Manager and may be deemed to have an indirect pecuniary interest in a percentage of the securities held by the CRCM Funds. The CRCM Funds and separately managed accounts hold directly in the aggregate 3,644,855 shares of common stock of the Issuer ("common stock"). The Reporting Person may be deemed to beneficially own a percentage of shares of common stock by virtue of his proportional interest in the CRCM Funds.

F2 · ownership.nature: The Reporting Person disclaims any beneficial ownership of any of the Issuer's securities reported herein, or otherwise, except as to securities representing the Reporting Person's proportional interest in the CRCM Funds, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of such other securities of the Issuer for purposes of Section 16 or for any other purpose.

SEC source: 0000898432-24-000825 · form4.xml · nonDerivative · entry 2

DING CHUN R · CIK 0001250077 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,523,655

F4 · price: On October 2, 2024, the CRCM Funds acquired 20,000 shares of common stock in a series of transactions at prices ranging from $13.10 to $13.54 per share. The price reported in Column 4 is a weighted average price. The detailed breakdown of executed transactions will be furnished upon request.

F1 · ownership.nature: Securities are owned directly by funds (the "CRCM Funds") and separately managed accounts managed by CRCM LP, a Delaware limited partnership and a registered investment adviser with the U.S. Securities and Exchange Commission (the "Investment Manager"). The Reporting Person holds ownership interests in the CRCM Funds. The Reporting Person is the managing partner of the Investment Manager and may be deemed to have an indirect pecuniary interest in a percentage of the securities held by the CRCM Funds. The CRCM Funds and separately managed accounts hold directly in the aggregate 3,644,855 shares of common stock of the Issuer ("common stock"). The Reporting Person may be deemed to beneficially own a percentage of shares of common stock by virtue of his proportional interest in the CRCM Funds.

F2 · ownership.nature: The Reporting Person disclaims any beneficial ownership of any of the Issuer's securities reported herein, or otherwise, except as to securities representing the Reporting Person's proportional interest in the CRCM Funds, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of such other securities of the Issuer for purposes of Section 16 or for any other purpose.

SEC source: 0000898432-24-000825 · form4.xml · nonDerivative · entry 1

DING CHUN R · CIK 0001250077 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,503,655

F3 · price: On October 1, 2024, the CRCM Funds acquired 7,629 shares of common stock in a series of transactions at prices ranging from $13.25 to $13.81 per share. The price reported in Column 4 is a weighted average price. The detailed breakdown of executed transactions will be furnished upon request.

F1 · ownership.nature: Securities are owned directly by funds (the "CRCM Funds") and separately managed accounts managed by CRCM LP, a Delaware limited partnership and a registered investment adviser with the U.S. Securities and Exchange Commission (the "Investment Manager"). The Reporting Person holds ownership interests in the CRCM Funds. The Reporting Person is the managing partner of the Investment Manager and may be deemed to have an indirect pecuniary interest in a percentage of the securities held by the CRCM Funds. The CRCM Funds and separately managed accounts hold directly in the aggregate 3,644,855 shares of common stock of the Issuer ("common stock"). The Reporting Person may be deemed to beneficially own a percentage of shares of common stock by virtue of his proportional interest in the CRCM Funds.

F2 · ownership.nature: The Reporting Person disclaims any beneficial ownership of any of the Issuer's securities reported herein, or otherwise, except as to securities representing the Reporting Person's proportional interest in the CRCM Funds, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of such other securities of the Issuer for purposes of Section 16 or for any other purpose.

SEC source: 0001628280-24-038211 · wk-form4_1724356940.xml · nonDerivative · entry 1

Freidin Aaron · CIK 0002024196 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 173,429

F1 · price: The price reported in Column 4 is a weighted average price calculated by the broker executing the sell-to-cover transactions. These shares were sold as part of a block trade in multiple transactions, and the Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate sales price.

SEC source: 0001628280-24-038210 · wk-form4_1724356928.xml · nonDerivative · entry 1

Ofman Joshua J. · CIK 0001822088 · President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 191,757

F1 · price: The price reported in Column 4 is a weighted average price calculated by the broker executing the sell-to-cover transactions. These shares were sold as part of a block trade in multiple transactions, and the Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate sales price.

SEC source: 0001628280-24-030867 · wk-form4_1719953564.xml · nonDerivative · entry 1

Freidin Aaron · CIK 0002024196 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 189,070

F1 · date: On June 24, 2024, Illumina, Inc. (Illumina) completed a pro rata spin-off distribution (the Distribution) of 85.5% of the outstanding shares of the Issuer to the holders of record of Illumina common stock as of June 13, 2024 (the Record Date). In connection with the Distribution, pursuant to the terms of the Employee Matters Agreement, dated as of June 21, 2024, by and between Illumina and the Issuer (the EMA), all outstanding cash-based equity appreciation incentive awards held by the Reporting Person were equitably adjusted and converted into equity-based awards with respect to the common stock of the Issuer, with such equitable adjustments determined based on the value of the award at the time of the Distribution (determined in accordance with the EMA) compared to the market capitalization of the Issuer for the four trading days following the Distribution.

F2 · shares: Represents the grant of restricted stock units (RSUs) of the Issuer upon the conversion of cash-based equity appreciation incentive awards held by the Reporting Person as of the Distribution in connection with the Distribution, in accordance with the terms of the EMA. The RSUs were granted pursuant to the GRAIL, Inc. 2024 Incentive Award Plan in a manner intended to preserve the aggregate intrinsic value of the underlying cash-based equity appreciation incentive awards, on generally the same terms and conditions as applied to the cash-based equity appreciation incentive awards prior to the Distribution (including vesting and payment schedules).

F3 · shares: Includes (i) 29,219 RSUs that vest on August 18, 2024, (ii) 56,899 RSUs that vest on November 16, 2024 (iii)1,260 RSUs that vest on March 4, 2025, (iv) 4,668 RSUs that vest on March 6, 2025, (v) 79,966 RSUs that vest on April 30, 2025, (vi) 1,703 RSUs that vest on August 18, 2025, (vii) 3,322 RSUs that vest on November 16, 2025, (viii) 1,261 RSUs that vest on March 4, 2026, (ix) 4,669 RSUs that vest on March 6, 2026 and (x) 4,669 RSUs that vest on March 6, 2027. Each RSU represents the right to receive, at settlement upon vesting, one share of common stock.

F4 · balance_after: Includes 1,434 shares of the common stock of the Issuer received in connection with the Distribution in respect of Illumina common stock held as of the Record Date.

SEC source: 0001628280-24-030869 · wk-form4_1719953574.xml · nonDerivative · entry 1

RAGUSA ROBERT P · CIK 0001222644 · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 476,035

F1 · date: On June 24, 2024, Illumina, Inc. (Illumina) completed a pro rata spin-off distribution (the Distribution) of 85.5% of the outstanding shares of the Issuer to the holders of record of Illumina common stock as of June 13, 2024 (the Record Date). In connection with the Distribution, pursuant to the terms of the Employee Matters Agreement, dated as of June 21, 2024, by and between Illumina and the Issuer (the EMA), all outstanding cash-based equity appreciation incentive awards held by the Reporting Person were equitably adjusted and converted into equity-based awards with respect to the common stock of the Issuer, with such equitable adjustments determined based on the value of the award at the time of the Distribution (determined in accordance with the EMA) compared to the market capitalization of the Issuer for the four trading days following the Distribution.

F2 · shares: Represents the grant of restricted stock units (RSUs) of the Issuer upon the conversion of cash-based equity appreciation incentive awards held by the Reporting Person as of the Distribution in connection with the Distribution, in accordance with the terms of the EMA. The RSUs were granted pursuant to the GRAIL, Inc. 2024 Incentive Award Plan in a manner intended to preserve the aggregate intrinsic value of the underlying cash-based equity appreciation incentive awards, on generally the same terms and conditions as applied to the cash-based equity appreciation incentive awards prior to the Distribution (including vesting and payment schedules).

F3 · shares: Includes (i) 242,974 RSUs that vest on October 14, 2024 (ii) 1,890 RSUs that vest on March 4, 2025, (iii) 14,006 RSUs that vest on March 6, 2025, (iv) 172,235 RSUs that vest on April 30, 2025, (v) 14,170 RSUs that vest on October 14, 2025 (vi) 1,891 RSUs that vest on March 4, 2026, (vii) 14,006 RSUs that vest on March 6, 2026 and (viii) 14,006 RSUs that vest on March 6, 2027. Each RSU represents the right to receive, at settlement upon vesting, one share of common stock.

F4 · balance_after: Includes 857 shares of the common stock of the Issuer received in connection with the Distribution in respect of Illumina common stock held as of the Record Date.

SEC source: 0001628280-24-030866 · wk-form4_1719953551.xml · nonDerivative · entry 1

Ofman Joshua J. · CIK 0001822088 · President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 265,841

F1 · date: On June 24, 2024, Illumina, Inc. (Illumina) completed a pro rata spin-off distribution (the Distribution) of 85.5% of the outstanding shares of the Issuer to the holders of record of Illumina common stock as of June 13, 2024 (the Record Date). In connection with the Distribution, pursuant to the terms of the Employee Matters Agreement, dated as of June 21, 2024, by and between Illumina and the Issuer (the EMA), all outstanding cash-based equity appreciation incentive awards held by the Reporting Person were equitably adjusted and converted into equity-based awards with respect to the common stock of the Issuer, with such equitable adjustments determined based on the value of the award at the time of the Distribution (determined in accordance with the EMA) compared to the market capitalization of the Issuer for the four trading days following the Distribution.

F2 · shares: Represents the grant of restricted stock units (RSUs) of the Issuer upon the conversion of cash-based equity appreciation incentive awards held by the Reporting Person as of the Distribution in connection with the Distribution, in accordance with the terms of the EMA. The RSUs were granted pursuant to the GRAIL, Inc. 2024 Incentive Award Plan in a manner intended to preserve the aggregate intrinsic value of the underlying cash-based equity appreciation incentive awards, on generally the same terms and conditions as applied to the cash-based equity appreciation incentive awards prior to the Distribution (including vesting and payment schedules).

F3 · shares: Includes (i) 138,403 RSUs that vest on August 18, 2024, (ii) 1,328 RSUs that vest on March 4, 2025, (iii) 5,502 RSUs that vest on March 6, 2025, (iv) 92,269 RSUs that vest on April 30, 2025, (v) 8,076 RSUs that vest on August 18, 2025, (vi) 1,329 RSUs that vest on March 4, 2026, (vii) 5,502 RSUs that vest on March 6, 2026 and (viii) 5,503 RSUs that vest on March 6, 2027. Each RSU represents the right to receive, at settlement upon vesting, one share of common stock.

F4 · balance_after: Includes 7,929 shares of the common stock of the Issuer received in connection with the Distribution in respect of Illumina common stock held as of the Record Date.

SEC source: 0001628280-24-030365 · wk-form4_1719522872.xml · nonDerivative · entry 1

SUMME GREGORY L · CIK 0001143422 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 26,470

F1 · shares: Represents an award of 26,470 restricted stock units ("RSUs") which will vest and become payable in three substantially equal annual installments beginning on June 21, 2025, subject to full accelerated vesting upon a change in control of the Issuer. Each RSU represents the right to receive, at settlement, one share of common stock. The RSUs will be settled in common stock upon vesting.

SEC source: 0001628280-24-030363 · wk-form4_1719522849.xml · nonDerivative · entry 1

CHASE WILLIAM J · CIK 0001563572 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 26,470

F1 · shares: Represents an award of 26,470 restricted stock units ("RSUs") which will vest and become payable in three substantially equal annual installments beginning on June 21, 2025, subject to full accelerated vesting upon a change in control of the Issuer. Each RSU represents the right to receive, at settlement, one share of common stock. The RSUs will be settled in common stock upon vesting.

SEC source: 0001628280-24-030364 · wk-form4_1719522861.xml · nonDerivative · entry 1

MIZELL STEVEN · CIK 0001189403 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 26,470

F1 · shares: Represents an award of 26,470 restricted stock units ("RSUs") which will vest and become payable in three substantially equal annual installments beginning on June 21, 2025, subject to full accelerated vesting upon a change in control of the Issuer. Each RSU represents the right to receive, at settlement, one share of common stock. The RSUs will be settled in common stock upon vesting.

SEC source: 0000950170-24-076883 · ownership.xml · nonDerivative · entry 1

ILLUMINA, INC. · CIK 0001110803 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 4,502,126

F1 · security: On June 3, 2024, Illumina, Inc. a Delaware corporation ("Illumina"), reported that it owned 100% of the membership interests of GRAIL, LLC. On June 21, 2024, GRAIL, LLC converted from a limited liability company to a corporation and changed its name to GRAIL, Inc. In connection therewith, the outstanding limited liability company interests of GRAIL, LLC changed to 31,049,147 shares of common stock, par value $0.001 per share of GRAIL, Inc.

F2 · kind: The record date for the pro rata distribution by Illumina of 26,547,021 shares of common stock of GRAIL, Inc. to the holders of shares of Illumina common stock was June 13, 2024. The distribution of shares of common stock of GRAIL, Inc. occurred on June 24, 2024.

F2 · price: The record date for the pro rata distribution by Illumina of 26,547,021 shares of common stock of GRAIL, Inc. to the holders of shares of Illumina common stock was June 13, 2024. The distribution of shares of common stock of GRAIL, Inc. occurred on June 24, 2024.