Tapewire

Nasdaq · USD

CSTL

CASTLE BIOSCIENCES INC

Export transactions ↓
Tapewire entity
359
SEC CIK
0001447362
Parsed reports
578

Last 12 months

Inside the activity.

0 purchase rows · 214 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 2025014
Dec 2025010
Jan 202603
Feb 202603
Mar 2026026
Apr 2026014
May 2026028
Jun 2026015
Jul 2026036
Aug 2026044
Sep 2026015
Oct 202606

Latest available

Insider transactions

JSON API
Reset

Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
May 13, 2021 Filed May 14, 2021 20:27 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 1,547 $50.51 $78,135.88
Disclosure

SEC source: 0001447362-21-000118 · wf-form4_162102401970974.xml · nonDerivative · entry 2

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 556,919

F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on December 11, 2020.

F3 · price: This transaction was executed in multiple trades at prices ranging from $50.285 to $51.215, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
May 13, 2021 Filed May 14, 2021 20:27 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 886 $49.75 $44,076.73
Disclosure

SEC source: 0001447362-21-000118 · wf-form4_162102401970974.xml · nonDerivative · entry 1

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 558,466

F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on December 11, 2020.

F2 · price: This transaction was executed in multiple trades at prices ranging from $49.260 to $50.250, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
May 12, 2021 Filed May 13, 2021 20:33 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 800 $52.88 $42,300.80
Disclosure

SEC source: 0001447362-21-000116 · wf-form4_162093800831488.xml · nonDerivative · entry 6

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 559,352

F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on December 11, 2020.

F7 · price: This transaction was executed in multiple trades at prices ranging from $52.570 to $53.350, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
May 12, 2021 Filed May 13, 2021 20:33 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 2,533 $51.94 $131,551.36
Disclosure

SEC source: 0001447362-21-000116 · wf-form4_162093800831488.xml · nonDerivative · entry 5

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 560,152

F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on December 11, 2020.

F6 · price: This transaction was executed in multiple trades at prices ranging from $51.570 to $52.460, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
May 11, 2021 Filed May 13, 2021 20:33 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 697 $54.40 $37,919.59
Disclosure

SEC source: 0001447362-21-000116 · wf-form4_162093800831488.xml · nonDerivative · entry 4

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 562,685

F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on December 11, 2020.

F5 · price: This transaction was executed in multiple trades at prices ranging from $54.240 to $54.540, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
May 11, 2021 Filed May 13, 2021 20:33 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 1,100 $53.69 $59,053.50
Disclosure

SEC source: 0001447362-21-000116 · wf-form4_162093800831488.xml · nonDerivative · entry 3

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 563,382

F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on December 11, 2020.

F4 · price: This transaction was executed in multiple trades at prices ranging from $53.210 to $54.180, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
May 11, 2021 Filed May 13, 2021 20:33 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 1,157 $52.60 $60,861.67
Disclosure

SEC source: 0001447362-21-000116 · wf-form4_162093800831488.xml · nonDerivative · entry 2

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 564,482

F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on December 11, 2020.

F3 · price: This transaction was executed in multiple trades at prices ranging from $52.185 to $53.180, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
May 11, 2021 Filed May 13, 2021 20:33 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 379 $51.63 $19,567.01
Disclosure

SEC source: 0001447362-21-000116 · wf-form4_162093800831488.xml · nonDerivative · entry 1

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 565,639

F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on December 11, 2020.

F2 · price: This transaction was executed in multiple trades at prices ranging from $51.110 to $52.070, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
May 10, 2021 Filed May 12, 2021 20:14 UTC GrantRestricted Stock Units · Derivative 1,460 $0.00 $0.00
Disclosure

SEC source: 0001447362-21-000112 · wf-form4_162085048170377.xml · derivative · entry 2

Olson Tiffany · CIK 0001442172 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,460

Underlying: Common Stock · 1,460 shares

Expires not disclosed

F2 · derivative.exercise_price: Each Restricted Stock Unit ("RSU") represents the right to receive one share of the Issuer's Common Stock.

F3 · derivative.exercise_date: The RSUs vest in three equal annual installments beginning on May 10, 2022.

F3 · derivative.expiration_date: The RSUs vest in three equal annual installments beginning on May 10, 2022.

Read SEC document
May 10, 2021 Filed May 12, 2021 20:14 UTC GrantStock option (right to buy) · Derivative 5,936 $0.00 Strike: $54.78 $0.00
Disclosure

SEC source: 0001447362-21-000112 · wf-form4_162085048170377.xml · derivative · entry 1

Olson Tiffany · CIK 0001442172 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,936

Underlying: Common Stock · 5,936 shares

Expires 2031-05-09

F1 · derivative.exercise_date: One-third of the shares shall vest on May 10, 2022, and the remaining shares shall vest in 24 equal monthly installments thereafter.

Read SEC document
April 28, 2021 Filed Apr 29, 2021 20:14 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 2,442 $69.37 $169,406.42
Disclosure

SEC source: 0001447362-21-000101 · wf-form4_161972726245517.xml · nonDerivative · entry 3

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 566,018

F1 · kind: These transactions were made pursuant to Rule 10b5-1 plans adopted by the Reporting Person on September 10, 2020 and December 11, 2020.

F4 · price: This transaction was executed in multiple trades at prices ranging from $69.090 to $69.810, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
April 28, 2021 Filed Apr 29, 2021 20:14 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 8,166 $68.72 $561,167.52
Disclosure

SEC source: 0001447362-21-000101 · wf-form4_161972726245517.xml · nonDerivative · entry 2

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 568,460

F1 · kind: These transactions were made pursuant to Rule 10b5-1 plans adopted by the Reporting Person on September 10, 2020 and December 11, 2020.

F3 · price: This transaction was executed in multiple trades at prices ranging from $68.085 to $69.075, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
April 28, 2021 Filed Apr 29, 2021 20:14 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 3,766 $67.38 $253,738.02
Disclosure

SEC source: 0001447362-21-000101 · wf-form4_161972726245517.xml · nonDerivative · entry 1

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 576,626

F1 · kind: These transactions were made pursuant to Rule 10b5-1 plans adopted by the Reporting Person on September 10, 2020 and December 11, 2020.

F2 · price: This transaction was executed in multiple trades at prices ranging from $67.040 to $68.035, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
April 27, 2021 Filed Apr 28, 2021 20:17 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 2,904 $71.35 $207,185.88
Disclosure

SEC source: 0001447362-21-000099 · wf-form4_161964101666972.xml · nonDerivative · entry 5

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 580,392

F1 · kind: These transactions were made pursuant to Rule 10b5-1 plans adopted by the Reporting Person on September 10, 2020 and December 11, 2020.

F6 · price: This transaction was executed in multiple trades at prices ranging from $71.050 to $71.690, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
April 27, 2021 Filed Apr 28, 2021 20:17 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 11,470 $70.76 $811,594.26
Disclosure

SEC source: 0001447362-21-000099 · wf-form4_161964101666972.xml · nonDerivative · entry 4

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 583,296

F1 · kind: These transactions were made pursuant to Rule 10b5-1 plans adopted by the Reporting Person on September 10, 2020 and December 11, 2020.

F5 · price: This transaction was executed in multiple trades at prices ranging from $70.050 to $71.030, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
April 26, 2021 Filed Apr 28, 2021 20:17 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 5,782 $70.06 $405,098.48
Disclosure

SEC source: 0001447362-21-000099 · wf-form4_161964101666972.xml · nonDerivative · entry 3

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 594,766

F1 · kind: These transactions were made pursuant to Rule 10b5-1 plans adopted by the Reporting Person on September 10, 2020 and December 11, 2020.

F4 · price: This transaction was executed in multiple trades at prices ranging from $69.850 to $70.300, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
April 26, 2021 Filed Apr 28, 2021 20:17 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 1,993 $69.30 $138,118.89
Disclosure

SEC source: 0001447362-21-000099 · wf-form4_161964101666972.xml · nonDerivative · entry 2

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 600,548

F1 · kind: These transactions were made pursuant to Rule 10b5-1 plans adopted by the Reporting Person on September 10, 2020 and December 11, 2020.

F3 · price: This transaction was executed in multiple trades at prices ranging from $68.845 to $69.650, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
April 26, 2021 Filed Apr 28, 2021 20:17 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 6,599 $68.34 $450,982.26
Disclosure

SEC source: 0001447362-21-000099 · wf-form4_161964101666972.xml · nonDerivative · entry 1

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 602,541

F1 · kind: These transactions were made pursuant to Rule 10b5-1 plans adopted by the Reporting Person on September 10, 2020 and December 11, 2020.

F2 · price: This transaction was executed in multiple trades at prices ranging from $67.840 to $68.770, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
April 22, 2021 Filed Apr 23, 2021 20:08 UTC SaleCommon Stock 2,769 $65.55 $181,507.95
Disclosure

SEC source: 0001447362-21-000093 · wf-form4_161920850708574.xml · nonDerivative · entry 8

BRADBURY DANIEL · CIK 0001236397 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By LLC

Disclosed balance after: 290,993

F1 · kind: The transactions on this Form 4 were made pursuant to a Rule 10b5-1 plan adopted by BioBrit, LLC (the "LLC") on September 5, 2020.

F10 · price: This transaction was executed in multiple trades at prices ranging from $65.310 to $65.780, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by the LLC, of which the Reporting Person is the managing member and has voting and investment power over the shares.

Read SEC document
April 22, 2021 Filed Apr 23, 2021 20:08 UTC SaleCommon Stock 3,431 $64.82 $222,411.14
Disclosure

SEC source: 0001447362-21-000093 · wf-form4_161920850708574.xml · nonDerivative · entry 7

BRADBURY DANIEL · CIK 0001236397 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By LLC

Disclosed balance after: 293,762

F1 · kind: The transactions on this Form 4 were made pursuant to a Rule 10b5-1 plan adopted by BioBrit, LLC (the "LLC") on September 5, 2020.

F9 · price: This transaction was executed in multiple trades at prices ranging from $64.310 to $65.300, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by the LLC, of which the Reporting Person is the managing member and has voting and investment power over the shares.

Read SEC document
April 22, 2021 Filed Apr 23, 2021 20:08 UTC SaleCommon Stock 1,300 $63.65 $82,738.50
Disclosure

SEC source: 0001447362-21-000093 · wf-form4_161920850708574.xml · nonDerivative · entry 6

BRADBURY DANIEL · CIK 0001236397 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By LLC

Disclosed balance after: 297,193

F1 · kind: The transactions on this Form 4 were made pursuant to a Rule 10b5-1 plan adopted by BioBrit, LLC (the "LLC") on September 5, 2020.

F8 · price: This transaction was executed in multiple trades at prices ranging from $63.260 to $64.230, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by the LLC, of which the Reporting Person is the managing member and has voting and investment power over the shares.

Read SEC document
April 21, 2021 Filed Apr 23, 2021 20:08 UTC SaleCommon Stock 1,550 $63.26 $98,046.80
Disclosure

SEC source: 0001447362-21-000093 · wf-form4_161920850708574.xml · nonDerivative · entry 5

BRADBURY DANIEL · CIK 0001236397 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By LLC

Disclosed balance after: 298,493

F1 · kind: The transactions on this Form 4 were made pursuant to a Rule 10b5-1 plan adopted by BioBrit, LLC (the "LLC") on September 5, 2020.

F7 · price: This transaction was executed in multiple trades at prices ranging from $63.170 to $63.410, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by the LLC, of which the Reporting Person is the managing member and has voting and investment power over the shares.

Read SEC document
April 21, 2021 Filed Apr 23, 2021 20:08 UTC SaleCommon Stock 3,970 $62.78 $249,252.48
Disclosure

SEC source: 0001447362-21-000093 · wf-form4_161920850708574.xml · nonDerivative · entry 4

BRADBURY DANIEL · CIK 0001236397 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By LLC

Disclosed balance after: 300,043

F1 · kind: The transactions on this Form 4 were made pursuant to a Rule 10b5-1 plan adopted by BioBrit, LLC (the "LLC") on September 5, 2020.

F6 · price: This transaction was executed in multiple trades at prices ranging from $62.170 to $63.150, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by the LLC, of which the Reporting Person is the managing member and has voting and investment power over the shares.

Read SEC document
April 21, 2021 Filed Apr 23, 2021 20:08 UTC SaleCommon Stock 1,480 $61.77 $91,413.68
Disclosure

SEC source: 0001447362-21-000093 · wf-form4_161920850708574.xml · nonDerivative · entry 3

BRADBURY DANIEL · CIK 0001236397 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By LLC

Disclosed balance after: 304,013

F1 · kind: The transactions on this Form 4 were made pursuant to a Rule 10b5-1 plan adopted by BioBrit, LLC (the "LLC") on September 5, 2020.

F5 · price: This transaction was executed in multiple trades at prices ranging from $61.110 to $62.100, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by the LLC, of which the Reporting Person is the managing member and has voting and investment power over the shares.

Read SEC document
April 21, 2021 Filed Apr 23, 2021 20:08 UTC SaleCommon Stock 300 $60.28 $18,084.90
Disclosure

SEC source: 0001447362-21-000093 · wf-form4_161920850708574.xml · nonDerivative · entry 2

BRADBURY DANIEL · CIK 0001236397 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By LLC

Disclosed balance after: 305,493

F1 · kind: The transactions on this Form 4 were made pursuant to a Rule 10b5-1 plan adopted by BioBrit, LLC (the "LLC") on September 5, 2020.

F4 · price: This transaction was executed in multiple trades at prices ranging from $59.860 to $60.495, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by the LLC, of which the Reporting Person is the managing member and has voting and investment power over the shares.

Read SEC document
April 21, 2021 Filed Apr 23, 2021 20:08 UTC SaleCommon Stock 200 $59.20 $11,839.00
Disclosure

SEC source: 0001447362-21-000093 · wf-form4_161920850708574.xml · nonDerivative · entry 1

BRADBURY DANIEL · CIK 0001236397 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By LLC

Disclosed balance after: 305,793

F1 · kind: The transactions on this Form 4 were made pursuant to a Rule 10b5-1 plan adopted by BioBrit, LLC (the "LLC") on September 5, 2020.

F2 · price: This transaction was executed in multiple trades at prices ranging from $58.770 to $59.620, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by the LLC, of which the Reporting Person is the managing member and has voting and investment power over the shares.

Read SEC document
April 15, 2021 Filed Apr 19, 2021 20:07 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 500 $69.63 $34,815.00
Disclosure

SEC source: 0001447362-21-000091 · wf-form4_161886281589883.xml · nonDerivative · entry 3

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 609,140

F1 · kind: These transactions were made pursuant to Rule 10b5-1 plans adopted by the Reporting Person on September 10, 2020 and December 11, 2020.

F4 · price: This transaction was executed in multiple trades at prices ranging from $69.36 to $69.80, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
April 15, 2021 Filed Apr 19, 2021 20:07 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 6,019 $68.74 $413,746.06
Disclosure

SEC source: 0001447362-21-000091 · wf-form4_161886281589883.xml · nonDerivative · entry 2

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 609,640

F1 · kind: These transactions were made pursuant to Rule 10b5-1 plans adopted by the Reporting Person on September 10, 2020 and December 11, 2020.

F3 · price: This transaction was executed in multiple trades at prices ranging from $68.33 to $69.31, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
April 15, 2021 Filed Apr 19, 2021 20:07 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 7,855 $68.02 $534,297.10
Disclosure

SEC source: 0001447362-21-000091 · wf-form4_161886281589883.xml · nonDerivative · entry 1

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 615,659

F1 · kind: These transactions were made pursuant to Rule 10b5-1 plans adopted by the Reporting Person on September 10, 2020 and December 11, 2020.

F2 · price: This transaction was executed in multiple trades at prices ranging from $67.33 to $68.32, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
April 14, 2021 Filed Apr 15, 2021 20:10 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 308 $71.69 $22,078.98
Disclosure

SEC source: 0001447362-21-000077 · wf-form4_161851738006629.xml · nonDerivative · entry 8

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 623,514

F1 · kind: These transactions were made pursuant to Rule 10b5-1 plans adopted by the Reporting Person on September 10, 2020 and December 11, 2020.

F9 · price: This transaction was executed in multiple trades at prices ranging from $71.680 to $71.690, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
April 14, 2021 Filed Apr 15, 2021 20:10 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 4,100 $71.19 $291,862.60
Disclosure

SEC source: 0001447362-21-000077 · wf-form4_161851738006629.xml · nonDerivative · entry 7

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 623,822

F1 · kind: These transactions were made pursuant to Rule 10b5-1 plans adopted by the Reporting Person on September 10, 2020 and December 11, 2020.

F8 · price: This transaction was executed in multiple trades at prices ranging from $70.670 to $71.650, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
April 14, 2021 Filed Apr 15, 2021 20:10 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 6,970 $70.20 $489,280.06
Disclosure

SEC source: 0001447362-21-000077 · wf-form4_161851738006629.xml · nonDerivative · entry 6

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 627,922

F1 · kind: These transactions were made pursuant to Rule 10b5-1 plans adopted by the Reporting Person on September 10, 2020 and December 11, 2020.

F7 · price: This transaction was executed in multiple trades at prices ranging from $69.640 to $70.600, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
April 14, 2021 Filed Apr 15, 2021 20:10 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 2,996 $68.82 $206,187.72
Disclosure

SEC source: 0001447362-21-000077 · wf-form4_161851738006629.xml · nonDerivative · entry 5

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 634,892

F1 · kind: These transactions were made pursuant to Rule 10b5-1 plans adopted by the Reporting Person on September 10, 2020 and December 11, 2020.

F6 · price: This transaction was executed in multiple trades at prices ranging from $68.470 to $69.410, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
April 13, 2021 Filed Apr 15, 2021 20:10 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 1,200 $69.41 $83,296.80
Disclosure

SEC source: 0001447362-21-000077 · wf-form4_161851738006629.xml · nonDerivative · entry 4

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 637,888

F1 · kind: These transactions were made pursuant to Rule 10b5-1 plans adopted by the Reporting Person on September 10, 2020 and December 11, 2020.

F5 · price: This transaction was executed in multiple trades at prices ranging from $69.190 to $69.630, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
April 13, 2021 Filed Apr 15, 2021 20:10 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 6,302 $68.51 $431,731.11
Disclosure

SEC source: 0001447362-21-000077 · wf-form4_161851738006629.xml · nonDerivative · entry 3

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 639,088

F1 · kind: These transactions were made pursuant to Rule 10b5-1 plans adopted by the Reporting Person on September 10, 2020 and December 11, 2020.

F4 · price: This transaction was executed in multiple trades at prices ranging from $68.190 to $69.080, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
April 13, 2021 Filed Apr 15, 2021 20:10 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 3,611 $67.69 $244,421.37
Disclosure

SEC source: 0001447362-21-000077 · wf-form4_161851738006629.xml · nonDerivative · entry 2

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 645,390

F1 · kind: These transactions were made pursuant to Rule 10b5-1 plans adopted by the Reporting Person on September 10, 2020 and December 11, 2020.

F3 · price: This transaction was executed in multiple trades at prices ranging from $67.145 to $68.120, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
April 13, 2021 Filed Apr 15, 2021 20:10 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 3,261 $66.58 $217,130.42
Disclosure

SEC source: 0001447362-21-000077 · wf-form4_161851738006629.xml · nonDerivative · entry 1

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 649,001

F1 · kind: These transactions were made pursuant to Rule 10b5-1 plans adopted by the Reporting Person on September 10, 2020 and December 11, 2020.

F2 · price: This transaction was executed in multiple trades at prices ranging from $66.140 to $67.060, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
April 07, 2021 Filed Apr 8, 2021 20:49 UTC SaleCommon Stock 849 $73.71 $62,577.24
Disclosure

SEC source: 0001447362-21-000072 · wf-form4_161791493268728.xml · nonDerivative · entry 6

BRADBURY DANIEL · CIK 0001236397 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By LLC

Disclosed balance after: 305,993

F1 · kind: The transactions on this Form 4 were made pursuant to a Rule 10b5-1 plan adopted by BioBrit, LLC (the "LLC") on September 5, 2020.

F8 · price: This transaction was executed in multiple trades at prices ranging from $73.340 to $74.060, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by the LLC, of which the Reporting Person is the managing member and has voting and investment power over the shares.

Read SEC document
April 07, 2021 Filed Apr 8, 2021 20:49 UTC SaleCommon Stock 1,757 $72.92 $128,125.71
Disclosure

SEC source: 0001447362-21-000072 · wf-form4_161791493268728.xml · nonDerivative · entry 5

BRADBURY DANIEL · CIK 0001236397 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By LLC

Disclosed balance after: 306,842

F1 · kind: The transactions on this Form 4 were made pursuant to a Rule 10b5-1 plan adopted by BioBrit, LLC (the "LLC") on September 5, 2020.

F7 · price: This transaction was executed in multiple trades at prices ranging from $72.285 to $73.250, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by the LLC, of which the Reporting Person is the managing member and has voting and investment power over the shares.

Read SEC document
April 07, 2021 Filed Apr 8, 2021 20:49 UTC SaleCommon Stock 1,394 $71.66 $99,889.86
Disclosure

SEC source: 0001447362-21-000072 · wf-form4_161791493268728.xml · nonDerivative · entry 4

BRADBURY DANIEL · CIK 0001236397 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By LLC

Disclosed balance after: 308,599

F1 · kind: The transactions on this Form 4 were made pursuant to a Rule 10b5-1 plan adopted by BioBrit, LLC (the "LLC") on September 5, 2020.

F6 · price: This transaction was executed in multiple trades at prices ranging from $71.270 to $72.230, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by the LLC, of which the Reporting Person is the managing member and has voting and investment power over the shares.

Read SEC document
April 07, 2021 Filed Apr 8, 2021 20:49 UTC SaleCommon Stock 3,500 $70.62 $247,184.00
Disclosure

SEC source: 0001447362-21-000072 · wf-form4_161791493268728.xml · nonDerivative · entry 3

BRADBURY DANIEL · CIK 0001236397 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By LLC

Disclosed balance after: 309,993

F1 · kind: The transactions on this Form 4 were made pursuant to a Rule 10b5-1 plan adopted by BioBrit, LLC (the "LLC") on September 5, 2020.

F5 · price: This transaction was executed in multiple trades at prices ranging from $70.180 to $71.065, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by the LLC, of which the Reporting Person is the managing member and has voting and investment power over the shares.

Read SEC document
April 06, 2021 Filed Apr 7, 2021 22:15 UTC SaleCommon Stock 40,000 $73.99 $2,959,708.00
Disclosure

SEC source: 0001447362-21-000070 · wf-form4_161783372923988.xml · nonDerivative · entry 3

KABAKOFF DAVID S · CIK 0001024008 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By L.P.

Disclosed balance after: 533,577

F1 · kind: The transactions on this Form 4 were made pursuant to a Rule 10b5-1 plan adopted by Sofinnova HealthQuest Partners, L.P. on December 17, 2020.

F5 · price: This transaction was executed in multiple trades at prices ranging from $73.4821 to $74.1945, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by Sofinnova HealthQuest Partners, L.P., or HealthQuest Partners. HealthQuest Venture Management, L.L.C., or HealthQuest Management, is the general partner of HealthQuest Partners. David Kabakoff, Ph.D., the Reporting Person, is a partner of HealthQuest Management. Garheng Kong is the managing member of HealthQuest Management and has sole voting and investment power over the shares held by HealthQuest Partners. Each of HealthQuest Management, Mr. Kong and Dr. Kabakoff disclaims beneficial ownership over all shares held by HealthQuest Partners except to the extent of any pecuniary interest therein.

Read SEC document
April 06, 2021 Filed Apr 8, 2021 20:49 UTC SaleCommon Stock 5,590 $74.06 $413,967.45
Disclosure

SEC source: 0001447362-21-000072 · wf-form4_161791493268728.xml · nonDerivative · entry 2

BRADBURY DANIEL · CIK 0001236397 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By LLC

Disclosed balance after: 313,493

F1 · kind: The transactions on this Form 4 were made pursuant to a Rule 10b5-1 plan adopted by BioBrit, LLC (the "LLC") on September 5, 2020.

F4 · price: This transaction was executed in multiple trades at prices ranging from $73.800 to $74.510, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by the LLC, of which the Reporting Person is the managing member and has voting and investment power over the shares.

Read SEC document
April 06, 2021 Filed Apr 8, 2021 20:49 UTC SaleCommon Stock 1,910 $73.54 $140,469.04
Disclosure

SEC source: 0001447362-21-000072 · wf-form4_161791493268728.xml · nonDerivative · entry 1

BRADBURY DANIEL · CIK 0001236397 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By LLC

Disclosed balance after: 319,083

F1 · kind: The transactions on this Form 4 were made pursuant to a Rule 10b5-1 plan adopted by BioBrit, LLC (the "LLC") on September 5, 2020.

F2 · price: This transaction was executed in multiple trades at prices ranging from $72.790 to $73.780, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by the LLC, of which the Reporting Person is the managing member and has voting and investment power over the shares.

Read SEC document
April 05, 2021 Filed Apr 7, 2021 22:15 UTC SaleCommon Stock 20,000 $73.22 $1,464,422.00
Disclosure

SEC source: 0001447362-21-000070 · wf-form4_161783372923988.xml · nonDerivative · entry 2

KABAKOFF DAVID S · CIK 0001024008 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By L.P.

Disclosed balance after: 573,577

F1 · kind: The transactions on this Form 4 were made pursuant to a Rule 10b5-1 plan adopted by Sofinnova HealthQuest Partners, L.P. on December 17, 2020.

F4 · price: This transaction was executed in multiple trades at prices ranging from $73.1857 to $73.2564, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by Sofinnova HealthQuest Partners, L.P., or HealthQuest Partners. HealthQuest Venture Management, L.L.C., or HealthQuest Management, is the general partner of HealthQuest Partners. David Kabakoff, Ph.D., the Reporting Person, is a partner of HealthQuest Management. Garheng Kong is the managing member of HealthQuest Management and has sole voting and investment power over the shares held by HealthQuest Partners. Each of HealthQuest Management, Mr. Kong and Dr. Kabakoff disclaims beneficial ownership over all shares held by HealthQuest Partners except to the extent of any pecuniary interest therein.

Read SEC document
April 05, 2021 Filed Apr 7, 2021 22:15 UTC SaleCommon Stock 50,000 $71.79 $3,589,600.00
Disclosure

SEC source: 0001447362-21-000070 · wf-form4_161783372923988.xml · nonDerivative · entry 1

KABAKOFF DAVID S · CIK 0001024008 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By L.P.

Disclosed balance after: 593,577

F1 · kind: The transactions on this Form 4 were made pursuant to a Rule 10b5-1 plan adopted by Sofinnova HealthQuest Partners, L.P. on December 17, 2020.

F2 · price: This transaction was executed in multiple trades at prices ranging from $71.1820 to $72.1647, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by Sofinnova HealthQuest Partners, L.P., or HealthQuest Partners. HealthQuest Venture Management, L.L.C., or HealthQuest Management, is the general partner of HealthQuest Partners. David Kabakoff, Ph.D., the Reporting Person, is a partner of HealthQuest Management. Garheng Kong is the managing member of HealthQuest Management and has sole voting and investment power over the shares held by HealthQuest Partners. Each of HealthQuest Management, Mr. Kong and Dr. Kabakoff disclaims beneficial ownership over all shares held by HealthQuest Partners except to the extent of any pecuniary interest therein.

Read SEC document
April 01, 2021 Filed Apr 2, 2021 22:05 UTC SaleCommon Stock 20,000 $70.80 $1,416,034.00
Disclosure

SEC source: 0001447362-21-000067 · wf-form4_161740106185755.xml · nonDerivative · entry 4

KABAKOFF DAVID S · CIK 0001024008 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By L.P.

Disclosed balance after: 643,577

F1 · kind: The transactions on this Form 4 were made pursuant to a Rule 10b5-1 plan adopted by Sofinnova HealthQuest Partners, L.P. on December 17, 2020.

F5 · price: This transaction was executed in multiple trades at prices ranging from $70.5502 to $71.0532, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by Sofinnova HealthQuest Partners, L.P., or HealthQuest Partners. HealthQuest Venture Management, L.L.C., or HealthQuest Management, is the general partner of HealthQuest Partners. David Kabakoff, Ph.D., the Reporting Person, is a partner of HealthQuest Management. Garheng Kong is the managing member of HealthQuest Management and has sole voting and investment power over the shares held by HealthQuest Partners. Each of HealthQuest Management, Mr. Kong and Dr. Kabakoff disclaims beneficial ownership over all shares held by HealthQuest Partners except to the extent of any pecuniary interest therein.

Read SEC document
April 01, 2021 Filed Apr 2, 2021 22:05 UTC SaleCommon Stock 40,000 $70.00 $2,800,052.00
Disclosure

SEC source: 0001447362-21-000067 · wf-form4_161740106185755.xml · nonDerivative · entry 3

KABAKOFF DAVID S · CIK 0001024008 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By L.P.

Disclosed balance after: 663,577

F1 · kind: The transactions on this Form 4 were made pursuant to a Rule 10b5-1 plan adopted by Sofinnova HealthQuest Partners, L.P. on December 17, 2020.

F4 · price: This transaction was executed in multiple trades at prices ranging from $69.3558 to $70.3535, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by Sofinnova HealthQuest Partners, L.P., or HealthQuest Partners. HealthQuest Venture Management, L.L.C., or HealthQuest Management, is the general partner of HealthQuest Partners. David Kabakoff, Ph.D., the Reporting Person, is a partner of HealthQuest Management. Garheng Kong is the managing member of HealthQuest Management and has sole voting and investment power over the shares held by HealthQuest Partners. Each of HealthQuest Management, Mr. Kong and Dr. Kabakoff disclaims beneficial ownership over all shares held by HealthQuest Partners except to the extent of any pecuniary interest therein.

Read SEC document
March 31, 2021 Filed Apr 2, 2021 22:05 UTC SaleCommon Stock 10,000 $68.15 $681,545.00
Disclosure

SEC source: 0001447362-21-000067 · wf-form4_161740106185755.xml · nonDerivative · entry 2

KABAKOFF DAVID S · CIK 0001024008 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By L.P.

Disclosed balance after: 703,577

F1 · kind: The transactions on this Form 4 were made pursuant to a Rule 10b5-1 plan adopted by Sofinnova HealthQuest Partners, L.P. on December 17, 2020.

F3 · ownership.nature: Held by Sofinnova HealthQuest Partners, L.P., or HealthQuest Partners. HealthQuest Venture Management, L.L.C., or HealthQuest Management, is the general partner of HealthQuest Partners. David Kabakoff, Ph.D., the Reporting Person, is a partner of HealthQuest Management. Garheng Kong is the managing member of HealthQuest Management and has sole voting and investment power over the shares held by HealthQuest Partners. Each of HealthQuest Management, Mr. Kong and Dr. Kabakoff disclaims beneficial ownership over all shares held by HealthQuest Partners except to the extent of any pecuniary interest therein.

Read SEC document
March 31, 2021 Filed Apr 2, 2021 22:05 UTC SaleCommon Stock 20,000 $67.56 $1,351,252.00
Disclosure

SEC source: 0001447362-21-000067 · wf-form4_161740106185755.xml · nonDerivative · entry 1

KABAKOFF DAVID S · CIK 0001024008 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By L.P.

Disclosed balance after: 713,577

F1 · kind: The transactions on this Form 4 were made pursuant to a Rule 10b5-1 plan adopted by Sofinnova HealthQuest Partners, L.P. on December 17, 2020.

F2 · price: This transaction was executed in multiple trades at prices ranging from $67.0821 to $68.0430, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by Sofinnova HealthQuest Partners, L.P., or HealthQuest Partners. HealthQuest Venture Management, L.L.C., or HealthQuest Management, is the general partner of HealthQuest Partners. David Kabakoff, Ph.D., the Reporting Person, is a partner of HealthQuest Management. Garheng Kong is the managing member of HealthQuest Management and has sole voting and investment power over the shares held by HealthQuest Partners. Each of HealthQuest Management, Mr. Kong and Dr. Kabakoff disclaims beneficial ownership over all shares held by HealthQuest Partners except to the extent of any pecuniary interest therein.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.