CRNX

SEC source: 0000950170-24-137923 · ownership.xml · nonDerivative · entry 1

Betz Stephen F. · CIK 0001886575 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 71,358

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0000950170-24-133297 · ownership.xml · nonDerivative · entry 1

Struthers Richard Scott · CIK 0001746298 · Director · President & CEO

10b5-1 filing: Plan reported

Ownership: Indirect · By Family Trust 4

Disclosed balance after: 100,000

F1 · kind: The sale reported in this Form 4 was effected automatically pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · price: The common stock was sold by the reporting person in open market transactions on the transaction date, with a weighted average sales price of $57.57 per share. The range of sales prices on the transaction date was $56.90 to $58.07 per share. Detailed information on the exact number of shares can be obtained from the issuer upon request.

SEC source: 0000950170-24-131064 · ownership.xml · nonDerivative · entry 1

Knight Jeff E. · CIK 0001881007 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 51,653

F1 · kind: The sale reported in this Form 4 was effected automatically pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · balance_after: Includes 501 shares acquired under the Issuer's Employee Stock Purchase Plan.

SEC source: 0000950170-25-010531 · ownership.xml · nonDerivative · entry 1

Betz Stephen F. · CIK 0001886575 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 71,358

F1 · date: Shares purchased under Crinetics Pharmaceuticals, Inc. 2018 Employee Stock Purchase Plan in a transaction exempt from Section 16(b) pursuant to Rule 16b-3(c),

SEC source: 0000950170-25-010530 · ownership.xml · nonDerivative · entry 1

Wilson Marc · CIK 0001702265 · CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 111,565

F1 · date: Shares purchased under Crinetics Pharmaceuticals, Inc. 2018 Employee Stock Purchase Plan in a transaction exempt from Section 16(b) pursuant to Rule 16b-3(c),

SEC source: 0000950170-24-113082 · ownership.xml · derivative · entry 3

Pizzuti Dana · CIK 0001948238 · Chief Med and Dev Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 139,042

Underlying: Common Stock · 14,375 shares

Expires 2032-10-10

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: The option is exercisable as follows: 25% of the shares subject to the option vest on September 30, 2023, and the remaining number of shares subject to the option vest monthly thereafter in thirty-six equal monthly installments, subject to the Reporting Person's continued employment with the Issuer on each such vesting date.

SEC source: 0000950170-24-113082 · ownership.xml · nonDerivative · entry 2

Pizzuti Dana · CIK 0001948238 · Chief Med and Dev Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 28,507

F1 · kind: The sale reported in this Form 4 was effected automatically pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · price: The common stock was sold by the reporting person in open market transactions on the transaction date, with a volume weighted average sales price of $54.63 per share. The range of sales prices on the transaction date was $53.53 to $55.29 per share. Detailed information on the exact number of shares can be obtained from the issuer upon request.

SEC source: 0000950170-24-113082 · ownership.xml · nonDerivative · entry 1

Pizzuti Dana · CIK 0001948238 · Chief Med and Dev Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 42,882

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0000950170-24-110416 · ownership.xml · derivative · entry 3

Wilson Marc · CIK 0001702265 · CFO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 89,000

Underlying: Common Stock · 25,000 shares

Expires 2031-02-26

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: 1/48th of the shares subject to the option vested on March 26, 2021, and 1/48th of the shares subject to the option vest monthly thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date.

SEC source: 0000950170-24-110416 · ownership.xml · nonDerivative · entry 2

Wilson Marc · CIK 0001702265 · CFO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 111,092

F1 · kind: The sale reported in this Form 4 was effected automatically pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · price: The common stock was sold by the reporting person in open market transactions on the transaction date, with a volume weighted average sales price of $51.11 per share. The range of sales prices on the transaction date was $50.28 to $51.54 per share. Detailed information on the exact number of shares can be obtained from the issuer upon request.

SEC source: 0000950170-24-110416 · ownership.xml · nonDerivative · entry 1

Wilson Marc · CIK 0001702265 · CFO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 136,092

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0000950170-24-105952 · ownership.xml · nonDerivative · entry 1

Betz Stephen F. · CIK 0001886575 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 68,576

F1 · kind: The sale reported in this Form 4 was effected automatically pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · price: The common stock was sold by the reporting person in open market transactions on the transaction date, with a volume weighted average sales price of $51.50 per share. The range of sales prices on the transaction date was $51.10 to $51.97 per share. Detailed information on the exact number of shares can be obtained from the issuer upon request.

SEC source: 0000950170-24-101434 · ownership.xml · nonDerivative · entry 1

Betz Stephen F. · CIK 0001886575 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 69,611

F1 · kind: The sale reported in this Form 4 was effected automatically pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

SEC source: 0000950170-24-097085 · ownership.xml · nonDerivative · entry 1

Betz Stephen F. · CIK 0001886575 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 72,611

F1 · kind: The sale reported in this Form 4 was effected automatically pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · price: The common stock was sold by the reporting person in open market transactions on the transaction date, with a volume weighted average sales price of $47.68 per share. The range of sales prices on the transaction date was $47.60 to $47.80 per share. Detailed information on the exact number of shares can be obtained from the issuer upon request.

SEC source: 0000950170-24-086935 · ownership.xml · nonDerivative · entry 1

Betz Stephen F. · CIK 0001886575 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 75,611

F1 · kind: The sale reported in this Form 4 was effected automatically pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · price: The common stock was sold by the reporting person in open market transactions on the transaction date, with a volume weighted average sales price of $53.43 per share. The range of sales prices on the transaction date was $53.41 to $53.45 per share. Detailed information on the exact number of shares can be obtained from the issuer upon request.

SEC source: 0000950170-24-086913 · ownership.xml · derivative · entry 3

Wilson Marc · CIK 0001702265 · CFO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 19,056 shares

Expires 2028-05-24

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: 1/48th of the shares subject to the option vested on June 25, 2018, and 1/48th of the shares subject to the option vest monthly thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date.

SEC source: 0000950170-24-086913 · ownership.xml · nonDerivative · entry 2

Wilson Marc · CIK 0001702265 · CFO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 111,092

F1 · kind: The sale reported in this Form 4 was effected automatically pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · price: The common stock was sold by the reporting person in open market transactions on the transaction date, with a volume weighted average sales price of $53.88 per share. The range of sales prices on the transaction date was $53.12 to $54.23 per share. Detailed information on the exact number of shares can be obtained from the issuer upon request.

SEC source: 0000950170-24-086913 · ownership.xml · nonDerivative · entry 1

Wilson Marc · CIK 0001702265 · CFO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 130,148

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0000950170-24-084346 · ownership.xml · derivative · entry 7

Knight Jeff E. · CIK 0001881007 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 85,313

Underlying: Common Stock · 5,687 shares

Expires 2033-03-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: 1/48th of the shares subject to the option vested on April 1, 2023, and 1/48th of the shares subject to the option vest monthly thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date.

SEC source: 0000950170-24-084346 · ownership.xml · derivative · entry 6

Knight Jeff E. · CIK 0001881007 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 20,213

Underlying: Common Stock · 2,887 shares

Expires 2032-02-29

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: 1/48th of the shares subject to the option vested on March 31, 2022, and 1/48th of the shares subject to the option vest monthly thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date.

SEC source: 0000950170-24-084346 · ownership.xml · derivative · entry 5

Knight Jeff E. · CIK 0001881007 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 112,501

Underlying: Common Stock · 17,499 shares

Expires 2031-09-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option is exercisable as follows: 25% of the shares subject to the option vest on August 30, 2022, and the remaining number of shares subject to the option vest monthly thereafter in thirty-six equal installments, subject to the Reporting Person's continued employment with the Issuer on each such vesting date.

SEC source: 0000950170-24-084346 · ownership.xml · nonDerivative · entry 4

Knight Jeff E. · CIK 0001881007 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 51,653

F1 · kind: The sale reported in this Form 4 was effected automatically pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

SEC source: 0000950170-24-084346 · ownership.xml · nonDerivative · entry 3

Knight Jeff E. · CIK 0001881007 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 78,653

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0000950170-24-084346 · ownership.xml · nonDerivative · entry 2

Knight Jeff E. · CIK 0001881007 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 72,966

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0000950170-24-084346 · ownership.xml · nonDerivative · entry 1

Knight Jeff E. · CIK 0001881007 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 70,079

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0000950170-24-084328 · ownership.xml · derivative · entry 3

Wilson Marc · CIK 0001702265 · CFO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 66,000

Underlying: Common Stock · 25,000 shares

Expires 2032-02-29

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: 1/48th of the shares subject to the option vested on March 31, 2022, and 1/48th of the shares subject to the option vest monthly thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date.

SEC source: 0000950170-24-084328 · ownership.xml · nonDerivative · entry 2

Wilson Marc · CIK 0001702265 · CFO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 111,092

F1 · kind: The sale reported in this Form 4 was effected automatically pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

SEC source: 0000950170-24-084328 · ownership.xml · nonDerivative · entry 1

Wilson Marc · CIK 0001702265 · CFO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 136,092

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0000950170-24-083221 · ownership.xml · nonDerivative · entry 1

Betz Stephen F. · CIK 0001886575 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 78,611

F1 · kind: The sale reported in this Form 4 was effected automatically pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · price: The common stock was sold by the reporting person in open market transactions on the transaction date, with a volume weighted average sales price of $48.55 per share. The range of sales prices on the transaction date was $48.63 to $48.46 per share. Detailed information on the exact number of shares can be obtained from the issuer upon request.

F3 · balance_after: Includes 968 shares acquired under the Issuer's Employee Stock Purchase Plan.

SEC source: 0000950170-24-082529 · ownership.xml · derivative · entry 3

Hassard James · CIK 0001799357 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 130,000

Underlying: Common Stock · 15,000 shares

Expires 2032-03-10

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: The option is exercisable as follows: 25% of the shares subject to the option vest on February 28, 2023, and the remaining number of shares subject to the option vest monthly thereafter in thirty-six equal monthly installments, subject to the Reporting Person's continued employment with the Issuer on each such vesting date.

SEC source: 0000950170-24-082529 · ownership.xml · nonDerivative · entry 2

Hassard James · CIK 0001799357 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 29,259

F1 · kind: The sale reported in this Form 4 was effected automatically pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · price: The common stock was sold by the reporting person in open market transactions on the transaction date, with a volume weighted average sales price of $44.08 per share. The range of sales prices on the transaction date was $43.71 to $44.41 per share. Detailed information on the exact number of shares can be obtained from the issuer upon request.

SEC source: 0000950170-24-082529 · ownership.xml · nonDerivative · entry 1

Hassard James · CIK 0001799357 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 44,259

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0000950170-24-081878 · ownership.xml · derivative · entry 3

Pizzuti Dana · CIK 0001948238 · Chief Med and Dev Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 153,417

Underlying: Common Stock · 14,375 shares

Expires 2032-10-10

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: The option is exercisable as follows: 25% of the shares subject to the option vest on September 30, 2023, and the remaining number of shares subject to the option vest monthly thereafter in thirty-six equal monthly installments, subject to the Reporting Person's continued employment with the Issuer on each such vesting date.

SEC source: 0000950170-24-081878 · ownership.xml · nonDerivative · entry 2

Pizzuti Dana · CIK 0001948238 · Chief Med and Dev Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 28,507

F1 · kind: The sale reported in this Form 4 was effected automatically pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · price: The common stock was sold by the reporting person in open market transactions on the transaction date, with a volume weighted average sales price of $44.87 per share. The range of sales prices on the transaction date was $44.24 to $45.55 per share. Detailed information on the exact number of shares can be obtained from the issuer upon request.

F3 · balance_after: Includes 721 shares acquired under the Issuer's Employee Stock Purchase Plan.

SEC source: 0000950170-24-081878 · ownership.xml · nonDerivative · entry 1

Pizzuti Dana · CIK 0001948238 · Chief Med and Dev Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 42,882

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0000950170-24-080557 · ownership.xml · derivative · entry 3

Wilson Marc · CIK 0001702265 · CFO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 19,056

Underlying: Common Stock · 32,129 shares

Expires 2028-05-24

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: 1/48th of the shares subject to the option vested on June 25, 2018, and 1/48th of the shares subject to the option vest monthly thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date.

SEC source: 0000950170-24-080557 · ownership.xml · nonDerivative · entry 2

Wilson Marc · CIK 0001702265 · CFO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 111,092

F1 · kind: The sale reported in this Form 4 was effected automatically pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · price: The common stock was sold by the reporting person in open market transactions on the transaction date, with a volume weighted average sales price of $43.61 per share. The range of sales prices on the transaction date was $43.28 to $44.13 per share. Detailed information on the exact number of shares can be obtained from the issuer upon request.

F3 · balance_after: Includes 462 shares acquired under the Issuer's Employee Stock Purchase Plan.

SEC source: 0000950170-24-080557 · ownership.xml · nonDerivative · entry 1

Wilson Marc · CIK 0001702265 · CFO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 143,221

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0000950170-24-079152 · ownership.xml · nonDerivative · entry 1

Knight Jeff E. · CIK 0001881007 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 52,580

F1 · kind: The sale reported in this Form 4 was effected automatically pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · balance_after: Includes 956 shares acquired under the Issuer's Employee Stock Purchase Plan.

SEC source: 0000950170-24-077905 · ownership.xml · nonDerivative · entry 1

Betz Stephen F. · CIK 0001886575 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 80,643

F1 · kind: The sale reported in this Form 4 was effected automatically pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · balance_after: The common stock was sold by the reporting person in open market transactions on the transaction date, with a volume weighted average sales price of $45.37 per share. The range of sales prices on the transaction date was $45.16 to $46.06 per share. Detailed information on the exact number of shares can be obtained from the issuer upon request.

SEC source: 0000950170-24-077402 · ownership.xml · derivative · entry 3

Pizzuti Dana · CIK 0001948238 · Chief Med and Dev Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 167,792

Underlying: Common Stock · 9,500 shares

Expires 2032-10-10

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option is exercisable as follows: 25% of the shares subject to the option vest on September 30, 2023, and the remaining number of shares subject to the option vest monthly thereafter in thirty-six equal monthly installments, subject to the Reporting Person's continued employment with the Issuer on each such vesting date.

SEC source: 0000950170-24-077402 · ownership.xml · nonDerivative · entry 2

Pizzuti Dana · CIK 0001948238 · Chief Med and Dev Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,786

F1 · price: The common stock was sold by the reporting person in open market transactions on the transaction date, with a volume weighted average sales price of $45.73 per share. The range of sales prices on the transaction date was $45.53 to $45.88 per share. Detailed information on the exact number of shares can be obtained from the issuer upon request.

SEC source: 0000950170-24-077402 · ownership.xml · nonDerivative · entry 1

Pizzuti Dana · CIK 0001948238 · Chief Med and Dev Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 37,286

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0000950170-24-076871 · ownership.xml · derivative · entry 3

Hassard James · CIK 0001799357 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 145,000

Underlying: Common Stock · 15,000 shares

Expires 2032-03-10

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: The option is exercisable as follows: 25% of the shares subject to the option vest on February 28, 2023, and the remaining number of shares subject to the option vest monthly thereafter in thirty-six equal monthly installments, subject to the Reporting Person's continued employment with the Issuer on each such vesting date.

SEC source: 0000950170-24-076871 · ownership.xml · nonDerivative · entry 2

Hassard James · CIK 0001799357 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 29,259

F1 · kind: The sale reported in this Form 4 was effected automatically pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · price: The common stock was sold by the reporting person in open market transactions on the transaction date, with a volume weighted average sales price of $44.66 per share. The range of sales prices on the transaction date was $43.96 to $45.11 per share. Detailed information on the exact number of shares can be obtained from the issuer upon request.

SEC source: 0000950170-24-076871 · ownership.xml · nonDerivative · entry 1

Hassard James · CIK 0001799357 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 44,259

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0000950170-24-071971 · ownership.xml · nonDerivative · entry 1

Betz Stephen F. · CIK 0001886575 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 83,643

F1 · kind: The sale reported in this Form 4 was effected automatically pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

SEC source: 0000950170-24-071931 · ownership.xml · derivative · entry 2

Deardorf Caren · CIK 0001871152 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 12,500

Underlying: Common Stock · 12,500 shares

Expires 2034-06-07

F2 · derivative.exercise_date: The stock option shall vest and become exercisable on the earlier of the first anniversary of the grant date or (b) the next occurring annual meeting of the Issuer's stockholders, subject to the Reporting Person's continued service on the board of directors of the Issuer through such vesting date.

SEC source: 0000950170-24-071931 · ownership.xml · nonDerivative · entry 1

Deardorf Caren · CIK 0001871152 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,400

F1 · price: The transaction reported on this line involves the receipt of restricted stock units, which represent the right to receive shares of the Issuer's Common Stock, with 100% vesting on the earlier of the first anniversary of the grant date or (b) the next occurring annual meeting of the Issuer's stockholders, subject to the Reporting Person's continued service on the board of directors of the Issuer through such vesting date.

SEC source: 0000950170-24-071928 · ownership.xml · derivative · entry 2

Okey Stephanie · CIK 0001742616 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 12,500

Underlying: Common Stock · 12,500 shares

Expires 2034-06-07

F2 · derivative.exercise_date: The stock option shall vest and become exercisable on the earlier of the first anniversary of the grant date or (b) the next occurring annual meeting of the Issuer's stockholders, subject to the Reporting Person's continued service on the board of directors of the Issuer through such vesting date.