CADL

SEC source: 0000950170-24-078172 · ownership.xml · derivative · entry 1

Martell Christopher · CIK 0001873465 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,240

Underlying: Common Stock · 14,240 shares

Expires 2034-06-26

F1 · derivative.exercise_date: This option is subject to time-based vesting. The shares underlying this option shall vest and become exercisable upon the earlier of (i) June 26, 2025 or (ii) the date of the next Annual Meeting of Stockholders of the Issuer; provided, however, that all vesting shall cease if the Reporting Person resigns from the Board of Directors (the "Board") of the Issuer or otherwise ceases to serve as a director, unless the Board determines that the circumstances warrant continuation of vesting.

SEC source: 0000950170-24-078174 · ownership.xml · derivative · entry 1

Nguyen Diem · CIK 0001814338 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,240

Underlying: Common Stock · 14,240 shares

Expires 2034-06-26

F1 · derivative.exercise_date: This option is subject to time-based vesting. The shares underlying this option shall vest and become exercisable upon the earlier of (i) June 26, 2025 or (ii) the date of the next Annual Meeting of Stockholders of the Issuer; provided, however, that all vesting shall cease if the Reporting Person resigns from the Board of Directors (the "Board") of the Issuer or otherwise ceases to serve as a director, unless the Board determines that the circumstances warrant continuation of vesting.

SEC source: 0000950170-24-078169 · ownership.xml · derivative · entry 1

Gaeta Renee · CIK 0001742428 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,240

Underlying: Common Stock · 14,240 shares

Expires 2034-06-26

F1 · derivative.exercise_date: This option is subject to time-based vesting. The shares underlying this option shall vest and become exercisable upon the earlier of (i) June 26, 2025 or (ii) the date of the next Annual Meeting of Stockholders of the Issuer; provided, however, that all vesting shall cease if the Reporting Person resigns from the Board of Directors (the "Board") of the Issuer or otherwise ceases to serve as a director, unless the Board determines that the circumstances warrant continuation of vesting.

SEC source: 0000950170-24-078168 · ownership.xml · derivative · entry 1

Benz Edward J. JR · CIK 0001691160 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,240

Underlying: Common Stock · 14,240 shares

Expires 2034-06-26

F1 · derivative.exercise_date: This option is subject to time-based vesting. The shares underlying this option shall vest and become exercisable upon the earlier of (i) June 26, 2025 or (ii) the date of the next Annual Meeting of Stockholders of the Issuer; provided, however, that all vesting shall cease if the Reporting Person resigns from the Board of Directors (the "Board") of the Issuer or otherwise ceases to serve as a director, unless the Board determines that the circumstances warrant continuation of vesting.

SEC source: 0000950170-24-078171 · ownership.xml · derivative · entry 1

Manning Paul B · CIK 0001494695 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,240

Underlying: Common Stock · 14,240 shares

Expires 2034-06-26

F1 · derivative.exercise_date: This option is subject to time-based vesting. The shares underlying this option shall vest and become exercisable upon the earlier of (i) June 26, 2025 or (ii) the date of the next Annual Meeting of Stockholders of the Issuer; provided, however, that all vesting shall cease if the Reporting Person resigns from the Board of Directors (the "Board") of the Issuer or otherwise ceases to serve as a director, unless the Board determines that the circumstances warrant continuation of vesting.

SEC source: 0000950170-24-078175 · ownership.xml · derivative · entry 1

PAPA JOSEPH C · CIK 0001242215 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,240

Underlying: Common Stock · 14,240 shares

Expires 2034-06-26

F1 · derivative.exercise_date: This option is subject to time-based vesting. The shares underlying this option shall vest and become exercisable upon the earlier of (i) June 26, 2025 or (ii) the date of the next Annual Meeting of Stockholders of the Issuer; provided, however, that all vesting shall cease if the Reporting Person resigns from the Board of Directors (the "Board") of the Issuer or otherwise ceases to serve as a director, unless the Board determines that the circumstances warrant continuation of vesting.

SEC source: 0000950170-24-078173 · ownership.xml · derivative · entry 1

Nabel Gary J. · CIK 0001867450 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,240

Underlying: Common Stock · 14,240 shares

Expires 2034-06-26

F1 · derivative.exercise_date: This option is subject to time-based vesting. The shares underlying this option shall vest and become exercisable upon the earlier of (i) June 26, 2025 or (ii) the date of the next Annual Meeting of Stockholders of the Issuer; provided, however, that all vesting shall cease if the Reporting Person resigns from the Board of Directors (the "Board") of the Issuer or otherwise ceases to serve as a director, unless the Board determines that the circumstances warrant continuation of vesting.

SEC source: 0000950170-24-078170 · ownership.xml · derivative · entry 1

Loggia Nicoletta · CIK 0001979825 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,240

Underlying: Common Stock · 14,240 shares

Expires 2034-06-26

F1 · derivative.exercise_date: This option is subject to time-based vesting. The shares underlying this option shall vest and become exercisable upon the earlier of (i) June 26, 2025 or (ii) the date of the next Annual Meeting of Stockholders of the Issuer; provided, however, that all vesting shall cease if the Reporting Person resigns from the Board of Directors (the "Board") of the Issuer or otherwise ceases to serve as a director, unless the Board determines that the circumstances warrant continuation of vesting.

SEC source: 0001209191-23-056982 · doc4.xml · nonDerivative · entry 1

Barone Francesca · CIK 0001909680 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 186,657

F1 · shares: These shares were withheld by the Issuer to satisfy tax withholding obligations associated with the vesting and settlement of restricted stock units.

SEC source: 0001209191-23-056985 · doc4.xml · nonDerivative · entry 1

Tyagarajan Seshu · CIK 0001923794 · Chief Technology Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 174,230

F1 · shares: These shares were withheld by the Issuer to satisfy tax withholding obligations associated with the vesting and settlement of restricted stock units.

SEC source: 0001209191-23-056986 · doc4.xml · nonDerivative · entry 1

Nichols William Garrett · CIK 0001618364 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 135,126

F1 · shares: These shares were withheld by the Issuer to satisfy tax withholding obligations associated with the vesting and settlement of restricted stock units.

SEC source: 0001209191-23-056981 · doc4.xml · nonDerivative · entry 1

Amello Jason · CIK 0001451805 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 202,009

F1 · shares: These shares were withheld by the Issuer to satisfy tax withholding obligations associated with the vesting and settlement of restricted stock units.

SEC source: 0001209191-23-056987 · doc4.xml · nonDerivative · entry 1

Tak Paul Peter · CIK 0001873905 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 373,556

F1 · shares: These shares were withheld by the Issuer to satisfy tax withholding obligations associated with the vesting and settlement of restricted stock units.

SEC source: 0001209191-23-056806 · doc4.xml · nonDerivative · entry 1

Barone Francesca · CIK 0001909680 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 206,405

F1 · shares: Represents restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of the Issuer's common stock upon vesting and settlement. 50% of the RSUs shall vest on June 30, 2024, and the remaining 50% on December 31, 2024, in each case subject to the Reporting Person's continued service on such vesting date.

SEC source: 0001209191-23-056803 · doc4.xml · nonDerivative · entry 1

Tyagarajan Seshu · CIK 0001923794 · Chief Technology Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 191,558

F1 · shares: Represents restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of the Issuer's common stock upon vesting and settlement. 50% of the RSUs shall vest on June 30, 2024, and the remaining 50% on December 31, 2024, in each case subject to the Reporting Person's continued service on such vesting date.

SEC source: 0001209191-23-056804 · doc4.xml · nonDerivative · entry 1

Nichols William Garrett · CIK 0001618364 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 147,301

F1 · shares: Represents restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of the Issuer's common stock upon vesting and settlement. 50% of the RSUs shall vest on June 30, 2024, and the remaining 50% on December 31, 2024, in each case subject to the Reporting Person's continued service on such vesting date.

SEC source: 0001209191-23-056802 · doc4.xml · nonDerivative · entry 1

Amello Jason · CIK 0001451805 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 222,162

F1 · shares: Represents restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of the Issuer's common stock upon vesting and settlement. 50% of the RSUs shall vest on June 30, 2024, and the remaining 50% on December 31, 2024, in each case subject to the Reporting Person's continued service on such vesting date.

SEC source: 0001209191-23-056801 · doc4.xml · nonDerivative · entry 1

Tak Paul Peter · CIK 0001873905 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 416,999

F1 · shares: Represents restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of the Issuer's common stock upon vesting and settlement. 50% of the RSUs shall vest on June 30, 2024, and the remaining 50% on December 31, 2024, in each case subject to the Reporting Person's continued service on such vesting date.

SEC source: 0001209191-23-040137 · doc4.xml · derivative · entry 1

Martell Christopher · CIK 0001873465 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,240

Underlying: Common Stock · 14,240 shares

Expires 2033-06-28

F1 · derivative.exercise_date: This option is subject to time-based vesting. The shares underlying this option shall vest and become exercisable upon the earlier of (i) June 28, 2024 or (ii) the date of the next Annual Meeting of Stockholders of the Issuer; provided, however, that all vesting shall cease if the Reporting Person resigns from the Board of Directors (the "Board") of the Issuer or otherwise ceases to serve as a director, unless the Board determines that the circumstances warrant continuation of vesting.

SEC source: 0001209191-23-040135 · doc4.xml · derivative · entry 1

Nguyen Diem · CIK 0001814338 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,240

Underlying: Common Stock · 14,240 shares

Expires 2033-06-28

F1 · derivative.exercise_date: This option is subject to time-based vesting. The shares underlying this option shall vest and become exercisable upon the earlier of (i) June 28, 2024 or (ii) the date of the next Annual Meeting of Stockholders of the Issuer; provided, however, that all vesting shall cease if the Reporting Person resigns from the Board of Directors (the "Board") of the Issuer or otherwise ceases to serve as a director, unless the Board determines that the circumstances warrant continuation of vesting.

SEC source: 0001209191-23-040136 · doc4.xml · derivative · entry 1

Gaeta Renee · CIK 0001742428 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,240

Underlying: Common Stock · 14,240 shares

Expires 2033-06-28

F1 · derivative.exercise_date: This option is subject to time-based vesting. The shares underlying this option shall vest and become exercisable upon the earlier of (i) June 28, 2024 or (ii) the date of the next Annual Meeting of Stockholders of the Issuer; provided, however, that all vesting shall cease if the Reporting Person resigns from the Board of Directors (the "Board") of the Issuer or otherwise ceases to serve as a director, unless the Board determines that the circumstances warrant continuation of vesting.

SEC source: 0001209191-23-040133 · doc4.xml · derivative · entry 1

Benz Edward J. JR · CIK 0001691160 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,240

Underlying: Common Stock · 14,240 shares

Expires 2033-06-28

F1 · derivative.exercise_date: This option is subject to time-based vesting. The shares underlying this option shall vest and become exercisable upon the earlier of (i) June 28, 2024 or (ii) the date of the next Annual Meeting of Stockholders of the Issuer; provided, however, that all vesting shall cease if the Reporting Person resigns from the Board of Directors (the "Board") of the Issuer or otherwise ceases to serve as a director, unless the Board determines that the circumstances warrant continuation of vesting.

SEC source: 0001209191-23-040134 · doc4.xml · derivative · entry 1

Manning Paul B · CIK 0001494695 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,240

Underlying: Common Stock · 14,240 shares

Expires 2033-06-28

F1 · derivative.exercise_date: This option is subject to time-based vesting. The shares underlying this option shall vest and become exercisable upon the earlier of (i) June 28, 2024 or (ii) the date of the next Annual Meeting of Stockholders of the Issuer; provided, however, that all vesting shall cease if the Reporting Person resigns from the Board of Directors (the "Board") of the Issuer or otherwise ceases to serve as a director, unless the Board determines that the circumstances warrant continuation of vesting.

SEC source: 0001209191-23-040132 · doc4.xml · derivative · entry 1

PAPA JOSEPH C · CIK 0001242215 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,240

Underlying: Common Stock · 14,240 shares

Expires 2033-06-28

F1 · derivative.exercise_date: This option is subject to time-based vesting. The shares underlying this option shall vest and become exercisable upon the earlier of (i) June 28, 2024 or (ii) the date of the next Annual Meeting of Stockholders of the Issuer; provided, however, that all vesting shall cease if the Reporting Person resigns from the Board of Directors (the "Board") of the Issuer or otherwise ceases to serve as a director, unless the Board determines that the circumstances warrant continuation of vesting.

SEC source: 0001209191-23-040131 · doc4.xml · derivative · entry 1

Aguilar-Cordova Estuardo · CIK 0001873919 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,240

Underlying: Common Stock · 14,240 shares

Expires 2033-06-28

F1 · derivative.exercise_date: This option is subject to time-based vesting. The shares underlying this option shall vest and become exercisable upon the earlier of (i) June 28, 2024 or (ii) the date of the next Annual Meeting of Stockholders of the Issuer; provided, however, that all vesting shall cease if the Reporting Person resigns from the Board of Directors (the "Board") of the Issuer or otherwise ceases to serve as a director, unless the Board determines that the circumstances warrant continuation of vesting.

SEC source: 0001209191-23-040130 · doc4.xml · derivative · entry 1

Nabel Gary J. · CIK 0001867450 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,240

Underlying: Common Stock · 14,240 shares

Expires 2033-06-28

F1 · derivative.exercise_date: This option is subject to time-based vesting. The shares underlying this option shall vest and become exercisable upon the earlier of (i) June 28, 2024 or (ii) the date of the next Annual Meeting of Stockholders of the Issuer; provided, however, that all vesting shall cease if the Reporting Person resigns from the Board of Directors (the "Board") of the Issuer or otherwise ceases to serve as a director, unless the Board determines that the circumstances warrant continuation of vesting.

SEC source: 0001209191-23-035623 · doc4.xml · derivative · entry 1

Loggia Nicoletta · CIK 0001979825 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 28,480

Underlying: Common Stock · 28,480 shares

Expires 2033-06-07

F1 · derivative.exercise_date: The shares underlying this option shall vest and become exercisable in 36 equal monthly installments, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0001209191-23-026549 · doc4.xml · derivative · entry 1

Barone Francesca · CIK 0001909680 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 90,000

Underlying: Common Stock · 90,000 shares

Expires 2033-04-28

F1 · derivative.exercise_date: This option is subject to time-based vesting. The shares underlying this option shall vest and become exercisable in forty-eight (48) equal monthly installments following April 28, 2023, subject to the Reporting Person's continued service on each vesting date.

SEC source: 0001209191-23-026574 · doc4.xml · derivative · entry 1

Tyagarajan Seshu · CIK 0001923794 · Chief Technology Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 90,000

Underlying: Common Stock · 90,000 shares

Expires 2033-04-28

F1 · derivative.exercise_date: This option is subject to time-based vesting. The shares underlying this option shall vest and become exercisable in forty-eight (48) equal monthly installments following April 28, 2023, subject to the Reporting Person's continued service on each vesting date.

SEC source: 0001209191-23-026569 · doc4.xml · derivative · entry 1

Nichols William Garrett · CIK 0001618364 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 45,000

Underlying: Common Stock · 45,000 shares

Expires 2033-04-28

F1 · derivative.exercise_date: This option is subject to time-based vesting. The shares underlying this option shall vest and become exercisable in forty-eight (48) equal monthly installments following April 28, 2023, subject to the Reporting Person's continued service on each vesting date.

SEC source: 0001209191-23-026542 · doc4.xml · derivative · entry 1

Amello Jason · CIK 0001451805 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 90,000

Underlying: Common Stock · 90,000 shares

Expires 2033-04-28

F1 · derivative.exercise_date: This option is subject to time-based vesting. The shares underlying this option shall vest and become exercisable in forty-eight (48) equal monthly installments following April 28, 2023, subject to the Reporting Person's continued service on each vesting date.

SEC source: 0001209191-23-026581 · doc4.xml · derivative · entry 1

Tak Paul Peter · CIK 0001873905 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 180,000

Underlying: Common Stock · 180,000 shares

Expires 2033-04-28

F1 · derivative.exercise_date: One third of the shares underlying this option shall vest and become exercisable in forty-eight equal monthly installments following April 28, 2023, subject to the Reporting Person's continued service on each vesting date. One third of the shares underlying this option shall vest and become exercisable if the average closing market price of the Issuer's common stock exceeds $3.00 per share for at least 20 consecutive trading days prior to the expiration of the option. The final third of shares underlying this option shall vest and become exercisable if the average closing market price of the Issuer's common stock exceeds $4.50 per share for at least 20 consecutive trading days prior to the expiration of the option. If either stock price hurdle is achieved prior to April 28, 2024, the applicable award would vest fully on April 28, 2024, so long as the Reporting Person remains an employee or service provider of the Issuer through such date.

SEC source: 0001209191-22-060692 · doc4.xml · nonDerivative · entry 2

Tyagarajan Seshu · CIK 0001923794 · Chief Technology Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,358

F2 · price: The price in Column 4 is a weighted average price. The shares were purchased in multiple transactions at prices ranging from $1.85 to $2.00. The reporting person hereby undertakes to provide upon request to the SEC staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the transaction was effected.

SEC source: 0001209191-22-060693 · doc4.xml · nonDerivative · entry 2

Martell Christopher · CIK 0001873465 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 152,000

F2 · price: The price in Column 4 is a weighted average price. The shares were purchased in multiple transactions at prices ranging from $1.88 to $1.98. The reporting person hereby undertakes to provide upon request to the SEC staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the transaction was effected.

SEC source: 0001209191-22-060691 · doc4.xml · nonDerivative · entry 2

Amello Jason · CIK 0001451805 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,568

F2 · price: The price in Column 4 is a weighted average price. The shares were purchased in multiple transactions at prices ranging from $1.85 to $2.00. The reporting person hereby undertakes to provide upon request to the SEC staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the transaction was effected.

SEC source: 0001209191-22-060694 · doc4.xml · nonDerivative · entry 2

PAPA JOSEPH C · CIK 0001242215 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,032

F2 · price: The price in Column 4 is a weighted average price. The shares were purchased in multiple transactions at prices ranging from $1.85 to $2.00. The reporting person hereby undertakes to provide upon request to the SEC staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the transaction was effected.

SEC source: 0001209191-22-060689 · doc4.xml · nonDerivative · entry 2

Tak Paul Peter · CIK 0001873905 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,985

F2 · price: The price in Column 4 is a weighted average price. The shares were purchased in multiple transactions at prices ranging from $1.89 to $2.00. The reporting person hereby undertakes to provide upon request to the SEC staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the transaction was effected.

SEC source: 0000899243-23-005523 · doc4a.xml · nonDerivative · entry 2

Martell Christopher · CIK 0001873465 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By GTAM1 2012 LLC

Disclosed balance after: 152,000

F2 · price: The price in Column 4 is a weighted average price. The shares were purchased in multiple transactions at prices ranging from $1.88 to $1.98. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Shares held by GTAM1 2012 LLC, which is wholly owned by a trust for which the Reporting Person serves as trustee. The Reporting Person disclaims beneficial ownership of these shares except to the extent of his pecuniary interest therein, if any.

SEC source: 0001209191-22-060700 · doc4.xml · nonDerivative · entry 1

Barone Francesca · CIK 0001909680 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,738

F1 · price: The price in Column 4 is a weighted average price. The shares were purchased in multiple transactions at prices ranging from $1.55 to $1.64. The reporting person hereby undertakes to provide upon request to the SEC staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the transaction was effected.

SEC source: 0001209191-22-060692 · doc4.xml · nonDerivative · entry 1

Tyagarajan Seshu · CIK 0001923794 · Chief Technology Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,000

F1 · price: The price in Column 4 is a weighted average price. The shares were purchased in multiple transactions at prices ranging from $1.55 to $1.80. The reporting person hereby undertakes to provide upon request to the SEC staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the transaction was effected.

SEC source: 0001209191-22-060693 · doc4.xml · nonDerivative · entry 1

Martell Christopher · CIK 0001873465 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 128,050

F1 · price: The price in Column 4 is a weighted average price. The shares were purchased in multiple transactions at prices ranging from $1.55 to $1.80. The reporting person hereby undertakes to provide upon request to the SEC staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the transaction was effected.

SEC source: 0001209191-22-060691 · doc4.xml · nonDerivative · entry 1

Amello Jason · CIK 0001451805 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,100

F1 · price: The price in Column 4 is a weighted average price. The shares were purchased in multiple transactions at prices ranging from $1.55 to $1.78. The reporting person hereby undertakes to provide upon request to the SEC staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the transaction was effected.

SEC source: 0001209191-22-060694 · doc4.xml · nonDerivative · entry 1

PAPA JOSEPH C · CIK 0001242215 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,014

F1 · price: The price in Column 4 is a weighted average price. The shares were purchased in multiple transactions at prices ranging from $1.55 to $1.80. The reporting person hereby undertakes to provide upon request to the SEC staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the transaction was effected.

SEC source: 0001209191-22-060689 · doc4.xml · nonDerivative · entry 1

Tak Paul Peter · CIK 0001873905 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,050

F1 · price: The price in Column 4 is a weighted average price. The shares were purchased in multiple transactions at prices ranging from $1.55 to $1.80. The reporting person hereby undertakes to provide upon request to the SEC staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the transaction was effected.

SEC source: 0000899243-23-005523 · doc4a.xml · nonDerivative · entry 1

Martell Christopher · CIK 0001873465 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By GTAM1 2012 LLC

Disclosed balance after: 128,050

F1 · price: The price in Column 4 is a weighted average price. The shares were purchased in multiple transactions at prices ranging from $1.55 to $1.80. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Shares held by GTAM1 2012 LLC, which is wholly owned by a trust for which the Reporting Person serves as trustee. The Reporting Person disclaims beneficial ownership of these shares except to the extent of his pecuniary interest therein, if any.

SEC source: 0000899243-22-037230 · doc4.xml · nonDerivative · entry 1

Barone Francesca · CIK 0001909680 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 92,377

F1 · shares: Represents restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of the Issuer's common stock upon vesting and settlement. 50% of the RSUs shall vest on November 28, 2023, and the remaining 50% on November 28, 2024, in each case subject to the Reporting Person's continued service on such vesting date.

SEC source: 0000899243-22-037224 · doc4.xml · nonDerivative · entry 1

Tyagarajan Seshu · CIK 0001923794 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 73,684

F1 · shares: Represents restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of the Issuer's common stock upon vesting and settlement. 50% of the RSUs shall vest on November 28, 2023, and the remaining 50% on November 28, 2024, in each case subject to the Reporting Person's continued service on such vesting date.

SEC source: 0000899243-22-037228 · doc4.xml · nonDerivative · entry 1

Nichols William Garrett · CIK 0001618364 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 58,479

F1 · shares: Represents restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of the Issuer's common stock upon vesting and settlement. 50% of the RSUs shall vest on November 28, 2023, and the remaining 50% on November 28, 2024, in each case subject to the Reporting Person's continued service on such vesting date.

SEC source: 0000899243-22-037232 · doc4.xml · nonDerivative · entry 1

Amello Jason · CIK 0001451805 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 90,877

F1 · shares: Represents restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of the Issuer's common stock upon vesting and settlement. 50% of the RSUs shall vest on November 28, 2023, and the remaining 50% on November 28, 2024, in each case subject to the Reporting Person's continued service on such vesting date.

SEC source: 0000899243-22-037231 · doc4.xml · nonDerivative · entry 1

Tak Paul Peter · CIK 0001873905 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 220,906

F1 · shares: Represents restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of the Issuer's common stock upon vesting and settlement. 50% of the RSUs shall vest on November 28, 2023, and the remaining 50% on November 28, 2024, in each case subject to the Reporting Person's continued service on such vesting date.