CADL

SEC source: 0001193125-26-412654 · ownership.xml · derivative · entry 1

Manning Paul B · CIK 0001494695 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,189

Underlying: Common Stock · 2,189 shares

Expires 2036-09-30

F1 · derivative.exercise_date: This award has been granted in lieu of normal quarterly cash payments. The underlying award quantity is fully vested at time of grant.

SEC source: 0001193125-26-412655 · ownership.xml · derivative · entry 1

PAPA JOSEPH C · CIK 0001242215 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,325

Underlying: Common Stock · 1,325 shares

Expires 2036-09-30

F1 · derivative.exercise_date: This award has been granted in lieu of normal quarterly cash payments. The underlying award quantity is fully vested at time of grant.

SEC source: 0001193125-26-412658 · ownership.xml · derivative · entry 1

Loggia Nicoletta · CIK 0001979825 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 380

Underlying: Common Stock · 380 shares

Expires 2036-09-30

F1 · derivative.exercise_date: This award has been granted in lieu of normal quarterly cash payments. The underlying award quantity is fully vested at time of grant.

SEC source: 0001873905-26-000002 · ownership.xml · nonDerivative · entry 3

Tak Paul Peter · CIK 0001873905 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 113,321

F1 · kind: This transaction reported on this Form 4 was effected pursuant to a 10b5-1 plan adopted on 3/13/2026 and modified on 6/11/2026.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $9.86 to $11.39, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote 3 herein.

SEC source: 0001873905-26-000002 · ownership.xml · derivative · entry 4

Tak Paul Peter · CIK 0001873905 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,638,968

Underlying: Common Stock · 125,000 shares

Expires 2030-10-10

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction reported on this Form 4 was effected pursuant to a 10b5-1 plan adopted on 3/13/2026 and modified on 6/11/2026.

F4 · derivative.exercise_date: 25% of this option vested and became exercisable on October 10, 2020, with another 25% vesting on September 14, 2021, and the remainder vesting in 36 substantially equal monthly installments thereafter.

SEC source: 0001873905-26-000002 · ownership.xml · nonDerivative · entry 2

Tak Paul Peter · CIK 0001873905 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 172,700

F1 · kind: This transaction reported on this Form 4 was effected pursuant to a 10b5-1 plan adopted on 3/13/2026 and modified on 6/11/2026.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $11.20 to $12.07, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote 2 herein.

SEC source: 0001873905-26-000002 · ownership.xml · nonDerivative · entry 1

Tak Paul Peter · CIK 0001873905 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 393,566

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction reported on this Form 4 was effected pursuant to a 10b5-1 plan adopted on 3/13/2026 and modified on 6/11/2026.

SEC source: 0001193125-26-387924 · ownership.xml · derivative · entry 1

Zimmermann Martine · CIK 0001994049 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 64,000

Underlying: Common Stock · 64,000 shares

Expires 2036-09-08

F1 · derivative.exercise_date: The shares underlying this option shall vest and become exercisable in thirty-six (36) equal monthly installments, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0001923794-26-000004 · ownership.xml · nonDerivative · entry 1

Tyagarajan Seshu · CIK 0001923794 · Chief Technology Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 76,865

F1 · kind: This transaction reported on this Form 4 was effected pursuant to a 10b5-1 trading plan adopted on 3/16/2026.

SEC source: 0002139479-26-000004 · ownership.xml · derivative · entry 1

Sims Mark E. · CIK 0002139479 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 285,000

Underlying: Common Stock · 285,000 shares

Expires 2036-07-06

F1 · derivative.exercise_date: 25% of the shares underlying this option shall vest and become exercisable on July 6, 2027, with the remainder vesting in thirty-six (36) equal monthly installments thereafter, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0001494695-26-000018 · ownership.xml · derivative · entry 1

Manning Paul B · CIK 0001494695 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,199

Underlying: Common Stock · 2,199 shares

Expires 2036-06-30

F1 · derivative.exercise_date: This award has been granted in lieu of normal quarterly cash payments. The underlying award quantity is fully vested at time of grant.

SEC source: 0001242215-26-000018 · ownership.xml · derivative · entry 1

PAPA JOSEPH C · CIK 0001242215 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,331

Underlying: Common Stock · 1,331 shares

Expires 2036-06-30

F1 · derivative.exercise_date: This award has been granted in lieu of normal quarterly cash payments. The underlying award quantity is fully vested at time of grant.

SEC source: 0001979825-26-000006 · ownership.xml · derivative · entry 1

Loggia Nicoletta · CIK 0001979825 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 381

Underlying: Common Stock · 381 shares

Expires 2036-06-30

F1 · derivative.exercise_date: This award has been granted in lieu of normal quarterly cash payments. The underlying award quantity is fully vested at time of grant.

SEC source: 0001909680-26-000002 · ownership.xml · nonDerivative · entry 1

Barone Francesca · CIK 0001909680 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 77,362

F1 · kind: This transaction reported on this Form 4 was effected pursuant to a 10b5-1 trading plan adopted on 3/16/2026.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $10.00 to $10.14, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote 2 herein.

SEC source: 0001923794-26-000002 · ownership.xml · nonDerivative · entry 1

Tyagarajan Seshu · CIK 0001923794 · Chief Technology Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 83,865

F1 · kind: This transaction reported on this Form 4 was effected pursuant to a 10b5-1 trading plan adopted on 3/16/2026.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $10.00 to $10.07 inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote 2 herein.

SEC source: 0002013423-26-000004 · ownership.xml · derivative · entry 1

Radhakrishnan Maha · CIK 0002013423 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 32,000

Underlying: Common Stock · 32,000 shares

Expires 2036-06-23

F1 · derivative.exercise_date: This option is subject to time-based vesting. The shares underlying this option shall vest and become exercisable upon the earlier of (i) June 23, 2027 or (ii) the date of the next Annual Meeting of Stockholders of the Issuer; provided, however, that all vesting shall cease if the Reporting Person resigns from the Board of Directors (the "Board") of the Issuer or otherwise ceases to serve as a director, unless the Board determines that the circumstances warrant continuation of vesting.

SEC source: 0001873465-26-000002 · ownership.xml · derivative · entry 1

Martell Christopher · CIK 0001873465 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 32,000

Underlying: Common Stock · 32,000 shares

Expires 2036-06-23

F1 · derivative.exercise_date: This option is subject to time-based vesting. The shares underlying this option shall vest and become exercisable upon the earlier of (i) June 23, 2027 or (ii) the date of the next Annual Meeting of Stockholders of the Issuer; provided, however, that all vesting shall cease if the Reporting Person resigns from the Board of Directors (the "Board") of the Issuer or otherwise ceases to serve as a director, unless the Board determines that the circumstances warrant continuation of vesting.

SEC source: 0001814338-26-000004 · ownership.xml · derivative · entry 1

Nguyen Diem · CIK 0001814338 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 32,000

Underlying: Common Stock · 32,000 shares

Expires 2036-06-23

F1 · derivative.exercise_date: This option is subject to time-based vesting. The shares underlying this option shall vest and become exercisable upon the earlier of (i) June 23, 2027 or (ii) the date of the next Annual Meeting of Stockholders of the Issuer; provided, however, that all vesting shall cease if the Reporting Person resigns from the Board of Directors (the "Board") of the Issuer or otherwise ceases to serve as a director, unless the Board determines that the circumstances warrant continuation of vesting.

SEC source: 0001742428-26-000004 · ownership.xml · derivative · entry 1

Gaeta Renee · CIK 0001742428 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 32,000

Underlying: Common Stock · 32,000 shares

Expires 2036-06-23

F1 · derivative.exercise_date: This option is subject to time-based vesting. The shares underlying this option shall vest and become exercisable upon the earlier of (i) June 23, 2027 or (ii) the date of the next Annual Meeting of Stockholders of the Issuer; provided, however, that all vesting shall cease if the Reporting Person resigns from the Board of Directors (the "Board") of the Issuer or otherwise ceases to serve as a director, unless the Board determines that the circumstances warrant continuation of vesting.

SEC source: 0001691160-26-000002 · ownership.xml · derivative · entry 1

Benz Edward J. JR · CIK 0001691160 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 32,000

Underlying: Common Stock · 32,000 shares

Expires 2036-06-23

F1 · derivative.exercise_date: This option is subject to time-based vesting. The shares underlying this option shall vest and become exercisable upon the earlier of (i) June 23, 2027 or (ii) the date of the next Annual Meeting of Stockholders of the Issuer; provided, however, that all vesting shall cease if the Reporting Person resigns from the Board of Directors (the "Board") of the Issuer or otherwise ceases to serve as a director, unless the Board determines that the circumstances warrant continuation of vesting.

SEC source: 0001494695-26-000015 · ownership.xml · derivative · entry 1

Manning Paul B · CIK 0001494695 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 32,000

Underlying: Common Stock · 32,000 shares

Expires 2036-06-23

F1 · derivative.exercise_date: This option is subject to time-based vesting. The shares underlying this option shall vest and become exercisable upon the earlier of (i) June 23, 2027 or (ii) the date of the next Annual Meeting of Stockholders of the Issuer; provided, however, that all vesting shall cease if the Reporting Person resigns from the Board of Directors (the "Board") of the Issuer or otherwise ceases to serve as a director, unless the Board determines that the circumstances warrant continuation of vesting.

SEC source: 0001242215-26-000016 · ownership.xml · derivative · entry 1

PAPA JOSEPH C · CIK 0001242215 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 32,000

Underlying: Common Stock · 32,000 shares

Expires 2036-06-23

F1 · derivative.exercise_date: This option is subject to time-based vesting. The shares underlying this option shall vest and become exercisable upon the earlier of (i) June 23, 2027 or (ii) the date of the next Annual Meeting of Stockholders of the Issuer; provided, however, that all vesting shall cease if the Reporting Person resigns from the Board of Directors (the "Board") of the Issuer or otherwise ceases to serve as a director, unless the Board determines that the circumstances warrant continuation of vesting.

SEC source: 0001979825-26-000004 · ownership.xml · derivative · entry 1

Loggia Nicoletta · CIK 0001979825 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 32,000

Underlying: Common Stock · 32,000 shares

Expires 2036-06-23

F1 · derivative.exercise_date: This option is subject to time-based vesting. The shares underlying this option shall vest and become exercisable upon the earlier of (i) June 23, 2027 or (ii) the date of the next Annual Meeting of Stockholders of the Issuer; provided, however, that all vesting shall cease if the Reporting Person resigns from the Board of Directors (the "Board") of the Issuer or otherwise ceases to serve as a director, unless the Board determines that the circumstances warrant continuation of vesting.

SEC source: 0001867450-26-000002 · ownership.xml · derivative · entry 1

Nabel Gary J. · CIK 0001867450 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 32,000

Underlying: Common Stock · 32,000 shares

Expires 2036-06-23

F1 · derivative.exercise_date: This option is subject to time-based vesting. The shares underlying this option shall vest and become exercisable upon the earlier of (i) June 23, 2027 or (ii) the date of the next Annual Meeting of Stockholders of the Issuer; provided, however, that all vesting shall cease if the Reporting Person resigns from the Board of Directors (the "Board") of the Issuer or otherwise ceases to serve as a director, unless the Board determines that the circumstances warrant continuation of vesting.

SEC source: 0001494695-26-000007 · ownership.xml · derivative · entry 1

Manning Paul B · CIK 0001494695 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 4,618

Underlying: Common Stock · 4,618 shares

Expires 2036-03-31

F1 · derivative.exercise_date: This award has been granted in lieu of normal quarterly cash payments. The underlying award quantity is fully vested at time of grant.

SEC source: 0001242215-26-000010 · ownership.xml · derivative · entry 1

PAPA JOSEPH C · CIK 0001242215 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,795

Underlying: Common Stock · 2,795 shares

Expires 2036-03-31

F1 · derivative.exercise_date: This award has been granted in lieu of normal quarterly cash payments. The underlying award quantity is fully vested at time of grant.

SEC source: 0001979825-26-000002 · ownership.xml · derivative · entry 1

Loggia Nicoletta · CIK 0001979825 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 779

Underlying: Common Stock · 779 shares

Expires 2036-03-31

F1 · derivative.exercise_date: This award has been granted in lieu of normal quarterly cash payments. The underlying award quantity is fully vested at time of grant.

SEC source: 0001193125-26-078246 · ownership.xml · nonDerivative · entry 1

Manning Paul B · CIK 0001494695 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · By Paul B. Manning Revocable Trust

Disclosed balance after: 2,763,527

F1 · ownership.nature: The shares are held by The Paul B. Manning Revocable Trust dated May 10, 2000 (the "Trust"). The Reporting Person is the trustee of the Trust and has sole voting and investment power with respect to the shares held by the Trust. The Reporting Person disclaims beneficial ownership of these shares except to the extent of his pecuniary interest therein.

SEC source: 0001193125-26-027392 · ownership.xml · derivative · entry 1

Barone Francesca · CIK 0001909680 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 232,000

Underlying: Common Stock · 232,000 shares

Expires 2036-01-26

F1 · derivative.exercise_date: This option is subject to time-based vesting. The shares underlying this option shall vest and become exercisable in forty-eight (48) equal monthly installments following January 26, 2026, subject to the Reporting Person's continued service on each vesting date.

SEC source: 0001193125-26-027406 · ownership.xml · derivative · entry 1

Schoch Charles · CIK 0002007349 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 232,000

Underlying: Common Stock · 232,000 shares

Expires 2036-01-26

F1 · derivative.exercise_date: This option is subject to time-based vesting. The shares underlying this option shall vest and become exercisable in forty-eight (48) equal monthly installments following January 26, 2026, subject to the Reporting Person's continued service on each vesting date.

SEC source: 0001193125-26-027412 · ownership.xml · derivative · entry 1

Tyagarajan Seshu · CIK 0001923794 · Chief Technology Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 154,000

Underlying: Common Stock · 154,000 shares

Expires 2036-01-26

F1 · derivative.exercise_date: This option is subject to time-based vesting. The shares underlying this option shall vest and become exercisable in forty-eight (48) equal monthly installments following January 26, 2026, subject to the Reporting Person's continued service on each vesting date.

SEC source: 0001193125-26-027409 · ownership.xml · derivative · entry 1

Nichols William Garrett · CIK 0001618364 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 136,500

Underlying: Common Stock · 136,500 shares

Expires 2036-01-26

F1 · derivative.exercise_date: This option is subject to time-based vesting. The shares underlying this option shall vest and become exercisable in forty-eight (48) equal monthly installments following January 26, 2026, subject to the Reporting Person's continued service on each vesting date.

SEC source: 0001193125-26-027396 · ownership.xml · derivative · entry 1

Tak Paul Peter · CIK 0001873905 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 629,000

Underlying: Common Stock · 629,000 shares

Expires 2036-01-26

F1 · derivative.exercise_date: This option is subject to time-based vesting. The shares underlying this option shall vest and become exercisable in forty-eight (48) equal monthly installments following January 26, 2026, subject to the Reporting Person's continued service on each vesting date.

SEC source: 0000950170-25-100320 · ownership.xml · derivative · entry 3

Nichols William Garrett · CIK 0001618364 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 29,377

Underlying: Common Stock · 937 shares

Expires 2033-04-28

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction reported on this Form 4 was effected pursuant to a 10b5-1 trading plan adopted on 11/22/2024.

F2 · derivative.exercise_date: This option is subject to time-based vesting. The shares underlying this option shall vest and become exercisable in forty-eight (48) equal monthly installments following April 28, 2023, subject to the Reporting Person's continued service on each vesting date.

SEC source: 0000950170-25-100320 · ownership.xml · nonDerivative · entry 2

Nichols William Garrett · CIK 0001618364 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 52,493

F1 · kind: This transaction reported on this Form 4 was effected pursuant to a 10b5-1 trading plan adopted on 11/22/2024.

SEC source: 0000950170-25-100320 · ownership.xml · nonDerivative · entry 1

Nichols William Garrett · CIK 0001618364 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 53,430

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction reported on this Form 4 was effected pursuant to a 10b5-1 trading plan adopted on 11/22/2024.

SEC source: 0000950170-25-093035 · ownership.xml · derivative · entry 3

Nichols William Garrett · CIK 0001618364 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 30,314

Underlying: Common Stock · 781 shares

Expires 2033-04-28

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction reported on this Form 4 was effected pursuant to a 10b5-1 trading plan adopted on 11/22/2024.

F2 · derivative.exercise_date: This option is subject to time-based vesting. The shares underlying this option shall vest and become exercisable in forty-eight (48) equal monthly installments following April 28, 2023, subject to the Reporting Person's continued service on each vesting date.

SEC source: 0000950170-25-093035 · ownership.xml · nonDerivative · entry 2

Nichols William Garrett · CIK 0001618364 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 52,493

F1 · kind: This transaction reported on this Form 4 was effected pursuant to a 10b5-1 trading plan adopted on 11/22/2024.

SEC source: 0000950170-25-093035 · ownership.xml · nonDerivative · entry 1

Nichols William Garrett · CIK 0001618364 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 53,274

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction reported on this Form 4 was effected pursuant to a 10b5-1 trading plan adopted on 11/22/2024.

SEC source: 0000950170-25-090194 · ownership.xml · nonDerivative · entry 1

Barone Francesca · CIK 0001909680 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 100,809

F1 · kind: Represents shares acquired from the Issuer in a registered direct offering pursuant to the terms of a Securities Purchase Agreement dated as of June 23, 2025.

SEC source: 0000950170-25-090193 · ownership.xml · nonDerivative · entry 1

Schoch Charles · CIK 0002007349 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 43,391

F1 · kind: Represents shares acquired from the Issuer in a registered direct offering pursuant to the terms of a Securities Purchase Agreement dated as of June 23, 2025.

SEC source: 0000950170-25-090199 · ownership.xml · nonDerivative · entry 1

Tyagarajan Seshu · CIK 0001923794 · Chief Technology Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 90,865

F1 · kind: Represents shares acquired from the Issuer in a registered direct offering pursuant to the terms of a Securities Purchase Agreement dated as of June 23, 2025.

SEC source: 0000950170-25-090196 · ownership.xml · nonDerivative · entry 1

Martell Christopher · CIK 0001873465 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · By Spouse

Disclosed balance after: 111,349

F1 · kind: Represents shares acquired from the Issuer in a registered direct offering pursuant to the terms of a Securities Purchase Agreement dated as of June 23, 2025.

F2 · ownership.nature: Shares held by Spouse.

SEC source: 0000950170-25-090197 · ownership.xml · nonDerivative · entry 1

Manning Paul B · CIK 0001494695 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · By Paul B. Manning Revocable Trust

Disclosed balance after: 2,213,069

F1 · kind: Represents shares acquired from the Issuer in a registered direct offering pursuant to the terms of a Securities Purchase Agreement dated as of June 23, 2025.

F2 · ownership.nature: The shares are held by The Paul B. Manning Revocable Trust dated May 10, 2000 (the "Trust"). The Reporting Person is the trustee of the Trust and has sole voting and investment power with respect to the shares held by the Trust. The Reporting Person disclaims beneficial ownership of these shares except to the extent of his pecuniary interest therein.

SEC source: 0000950170-25-090191 · ownership.xml · nonDerivative · entry 1

PAPA JOSEPH C · CIK 0001242215 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · By Joseph C. Papa Revocable Living Trust

Disclosed balance after: 64,239

F1 · kind: Represents shares acquired from the Issuer in a registered direct offering pursuant to the terms of a Securities Purchase Agreement dated as of June 23, 2025.

F2 · ownership.nature: Shares held by Joseph C. Papa Revocable Living Trust, which is wholly owned by a trust for which the Reporting Person serves as trustee. The Reporting Person disclaims beneficial ownership of these shares except to the extent of his pecuniary interest therein, if any.

SEC source: 0000950170-25-090195 · ownership.xml · nonDerivative · entry 1

Loggia Nicoletta · CIK 0001979825 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,141

F1 · kind: Represents shares acquired from the Issuer in a registered direct offering pursuant to the terms of a Securities Purchase Agreement dated as of June 23, 2025.

SEC source: 0000950170-25-090198 · ownership.xml · nonDerivative · entry 1

Tak Paul Peter · CIK 0001873905 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 268,566

F1 · kind: Represents shares acquired from the Issuer in a registered direct offering pursuant to the terms of a Securities Purchase Agreement dated as of June 23, 2025.

SEC source: 0000950170-25-090192 · ownership.xml · nonDerivative · entry 1

Nabel Gary J. · CIK 0001867450 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,353

F1 · kind: Represents shares acquired from the Issuer in a registered direct offering pursuant to the terms of a Securities Purchase Agreement dated as of June 23, 2025.

SEC source: 0000950170-25-089473 · ownership.xml · derivative · entry 1

Schoch Charles · CIK 0002007349 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 50,000

Underlying: Common Stock · 50,000 shares

Expires 2035-06-20

F1 · derivative.exercise_date: This option is subject to time-based vesting. 25% of the shares underlying this option shall vest and become exercisable on June 20, 2026, with the remainder vesting in thirty-six (36) equal monthly installments thereafter, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0000950170-25-087700 · ownership.xml · derivative · entry 1

Martell Christopher · CIK 0001873465 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,240

Underlying: Common Stock · 14,240 shares

Expires 2035-06-17

F1 · derivative.exercise_date: This option is subject to time-based vesting. The shares underlying this option shall vest and become exercisable upon the earlier of (i) June 17, 2026 or (ii) the date of the next Annual Meeting of Stockholders of the Issuer; provided, however, that all vesting shall cease if the Reporting Person resigns from the Board of Directors (the "Board") of the Issuer or otherwise ceases to serve as a director, unless the Board determines that the circumstances warrant continuation of vesting.