BRTX

SEC source: 0001567619-23-003332 · doc1.xml · derivative · entry 2

Williams Patrick F. · CIK 0001562229 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,028

Underlying: Common Stock · 32,028 shares

Expires 2033-02-17

F2 · derivative.exercise_date: The option vests and becomes exercisable in twelve monthly installments of 2,669 shares beginning on March 17, 2023 and continuing every month thereafter until fully vested.

SEC source: 0001567619-23-003330 · doc1.xml · derivative · entry 2

Kukekov Nickolay V. · CIK 0001827573 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,028

Underlying: Common Stock · 32,028 shares

Expires 2033-02-17

F2 · derivative.exercise_date: The option vests and becomes exercisable in twelve monthly installments of 2,669 shares beginning on March 17, 2023 and continuing each month thereafter until fully vested.

SEC source: 0001567619-23-003328 · doc1.xml · derivative · entry 3

Kristal Robert Eugene · CIK 0001893955 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 88,968

Underlying: Common Stock · 88,968 shares

Expires 2033-02-17

F2 · derivative.exercise_date: The option vests and becomes exercisable to the extent of 44,484 shares on February 17, 2023 with the remaining 44,484 shares vesting in eight nearly-equal quarterly installments beginning on February 17, 2024 and continuing every three months thereafter until fully vested.

SEC source: 0001567619-23-003324 · doc1.xml · derivative · entry 4

ALSTODT LANCE · CIK 0001756228 · Director · President, CEO, COB · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 106,762

Underlying: Common Stock · 106,762 shares

Expires 2033-02-17

F4 · derivative.exercise_date: The option vests and becomes exercisable to the extent of 53,381 shares on February 17, 2023 with the remaining 53,381 shares vesting in eight nearly-equal quarterly installments beginning on February 17, 2024 and continuing every three months thereafter until fully vested.

SEC source: 0001567619-23-001697 · doc1.xml · nonDerivative · entry 1

ALSTODT LANCE · CIK 0001756228 · Director · President, CEO, COB

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 187,321

F1 · price: This transaction was executed in multiple trades at prices ranging from $3.07 to $3.12 per share. The price reported above reflects the weighted average purchase price. The reporting person hereby undertakes to provide, upon request to the SEC staff, the issuer or a security holder of the issuer, full information regarding the number of shares and prices at which the transactions were effected.

F2 · balance_after: Includes 99,899 shares received pursuant to an unvested restricted stock unit grant. Such shares vest to the extent of 1,037 shares on February 18, 2023, 49,949 shares on March 18, 2023 and 48,913 shares on March 18, 2024.

SEC source: 0001567619-23-001399 · doc1.xml · nonDerivative · entry 1

ALSTODT LANCE · CIK 0001756228 · Director · President, CEO, COB

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 186,921

F1 · balance_after: Includes 99,899 shares received pursuant to an unvested restricted stock unit grant. Such shares vest to the extent of 1,037 shares on February 18, 2023, 49,949 shares on March 18, 2023 and 48,913 shares on March 18, 2024.

SEC source: 0001567619-23-001186 · doc1.xml · nonDerivative · entry 2

ALSTODT LANCE · CIK 0001756228 · Director · President, CEO, COB

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 186,721

F1 · balance_after: Includes 99,899 shares received pursuant to an unvested restricted stock unit grant. Such shares vest to the extent of 1,037 shares on February 18, 2023, 49,949 shares on March 18, 2023 and 48,913 shares on March 18, 2024.

SEC source: 0001567619-23-001186 · doc1.xml · nonDerivative · entry 1

ALSTODT LANCE · CIK 0001756228 · Director · President, CEO, COB

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 186,621

F1 · balance_after: Includes 99,899 shares received pursuant to an unvested restricted stock unit grant. Such shares vest to the extent of 1,037 shares on February 18, 2023, 49,949 shares on March 18, 2023 and 48,913 shares on March 18, 2024.

SEC source: 0001567619-23-001056 · doc1.xml · nonDerivative · entry 3

ALSTODT LANCE · CIK 0001756228 · Director · President, CEO, COB

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 186,521

F1 · balance_after: Includes 99,899 shares received pursuant to an unvested restricted stock unit grant. Such shares vest to the extent of 1,037 shares on February 18, 2023, 49,949 shares on March 18, 2023 and 48,913 shares on March 18, 2024.

SEC source: 0001567619-23-001056 · doc1.xml · nonDerivative · entry 2

ALSTODT LANCE · CIK 0001756228 · Director · President, CEO, COB

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 186,421

F1 · balance_after: Includes 99,899 shares received pursuant to an unvested restricted stock unit grant. Such shares vest to the extent of 1,037 shares on February 18, 2023, 49,949 shares on March 18, 2023 and 48,913 shares on March 18, 2024.

SEC source: 0001567619-23-001056 · doc1.xml · nonDerivative · entry 1

ALSTODT LANCE · CIK 0001756228 · Director · President, CEO, COB

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 186,321

F1 · balance_after: Includes 99,899 shares received pursuant to an unvested restricted stock unit grant. Such shares vest to the extent of 1,037 shares on February 18, 2023, 49,949 shares on March 18, 2023 and 48,913 shares on March 18, 2024.

SEC source: 0001567619-23-000770 · doc1.xml · nonDerivative · entry 1

ALSTODT LANCE · CIK 0001756228 · Director · President, CEO, COB

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 186,121

F1 · price: Includes 100,935 shares received pursuant to an unvested restricted stock unit grant. Such shares vest to the extent of 1,036 shares on January 18, 2023, 1,037 shares on February 18, 2023, 49,949 shares on March 18, 2023 and 48,913 shares on March 18, 2024.

F1 · balance_after: Includes 100,935 shares received pursuant to an unvested restricted stock unit grant. Such shares vest to the extent of 1,036 shares on January 18, 2023, 1,037 shares on February 18, 2023, 49,949 shares on March 18, 2023 and 48,913 shares on March 18, 2024.

SEC source: 0001567619-22-022055 · doc1.xml · nonDerivative · entry 2

ALSTODT LANCE · CIK 0001756228 · Director · President, CEO, COB

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 186,021

F1 · balance_after: Includes 100,935 shares received pursuant to an unvested restricted stock unit grant. Such shares vest to the extent of 1,036 shares on January 18, 2023, 1,037 shares on February 18, 2023, 49,949 shares on March 18, 2023 and 48,913 shares on March 18, 2024.

SEC source: 0001567619-22-022055 · doc1.xml · nonDerivative · entry 1

ALSTODT LANCE · CIK 0001756228 · Director · President, CEO, COB

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 185,921

F1 · balance_after: Includes 100,935 shares received pursuant to an unvested restricted stock unit grant. Such shares vest to the extent of 1,036 shares on January 18, 2023, 1,037 shares on February 18, 2023, 49,949 shares on March 18, 2023 and 48,913 shares on March 18, 2024.

SEC source: 0001567619-22-021408 · doc1.xml · nonDerivative · entry 1

ALSTODT LANCE · CIK 0001756228 · Director · President, CEO, COB

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 185,721

F1 · price: This transaction was executed in multiple trades at prices ranging from $2.93 to $3.00 per share. The price reported above reflects the weighted average purchase price. The reporting person hereby undertakes to provide, upon request to the SEC staff, the issuer or a security holder of the issuer, full information regarding the number of shares and prices at which the transactions were effected.

F2 · balance_after: Includes 101,972 shares received pursuant to an unvested restricted stock unit grant. Such shares vest to the extent of 1,037 shares on December 18, 2022 and February 18, 2023, 1,036 shares on January 18, 2023, 49,949 shares on March 18, 2023 and 48,913 shares on March 18, 2024.

SEC source: 0001567619-23-004348 · doc1.xml · nonDerivative · entry 2

Broadrick Dale · CIK 0001677513 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 299,073

SEC source: 0001567619-23-004348 · doc1.xml · nonDerivative · entry 1

Broadrick Dale · CIK 0001677513 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 298,973

SEC source: 0001567619-22-020707 · doc1.xml · nonDerivative · entry 1

Silva Francisco · CIK 0001527241 · Director · VP of Research and Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 166,046

F1 · balance_after: Includes 101,972 shares received pursuant to an unvested restricted stock unit grant. Such shares vest to the extent of 1,037 shares on December 18, 2022 and February 18, 2023, 1,036 shares on January 18, 2023, 49,949 shares on March 18, 2023 and 48,913 shares on March 18, 2024.

SEC source: 0001567619-22-020651 · doc1.xml · nonDerivative · entry 1

ALSTODT LANCE · CIK 0001756228 · Director · President, CEO, COB

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 183,921

F1 · price: This transaction was executed in multiple trades at prices ranging from $2.80 to $2.97 per share. The price reported above reflects the weighted average purchase price. The reporting person hereby undertakes to provide, upon request to the SEC staff, the issuer or a security holder of the issuer, full information regarding the number of shares and prices at which the transactions were effected.

F2 · balance_after: Includes 101,972 shares received pursuant to an unvested restricted stock unit grant. Such shares vest to the extent of 1,037 shares on December 18, 2022 and February 18, 2023, 1,036 shares on January 18, 2023, 49,949 shares on March 18, 2023 and 48,913 shares on March 18, 2024.

SEC source: 0001567619-22-019201 · doc1.xml · derivative · entry 2

Paccasassi Robert · CIK 0001751339 · VP, QA and Reg Compliance

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,277

Underlying: Common Stock · 8,277 shares

Expires 2031-11-04

F2 · price: The reported transactions involved an amendment of an outstanding stock option, resulting in the deemed cancellation of the "old" stock option and the grant of a "replacement" stock option with a reduced exercise price.

F1 · derivative.exercise_date: The option vests and becomes exercisable in eight nearly-equal quarterly installments beginning on February 4, 2022 and continuing every three months thereafter until fully vested.

SEC source: 0001567619-22-019201 · doc1.xml · derivative · entry 1

Paccasassi Robert · CIK 0001751339 · VP, QA and Reg Compliance

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 8,277 shares

Expires 2031-11-04

F2 · price: The reported transactions involved an amendment of an outstanding stock option, resulting in the deemed cancellation of the "old" stock option and the grant of a "replacement" stock option with a reduced exercise price.

F1 · derivative.exercise_date: The option vests and becomes exercisable in eight nearly-equal quarterly installments beginning on February 4, 2022 and continuing every three months thereafter until fully vested.

SEC source: 0001567619-22-019193 · doc1.xml · derivative · entry 2

Kukekov Nickolay V. · CIK 0001827573 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,236

Underlying: Common Stock · 25,236 shares

Expires 2031-11-04

F2 · price: The reported transactions involved an amendment of an outstanding stock option, resulting in the deemed cancellation of the "old" stock option and the grant of a "replacement" stock option with a reduced exercise price.

F1 · derivative.exercise_date: The option vests and becomes exercisable to the extent of 12,618 shares on November 4, 2021 with the remaining 12,618 shares vesting quarterly in eight nearly equal installments beginning November 4, 2022 and continuing every three months thereafter until fully vested.

SEC source: 0001567619-22-019193 · doc1.xml · derivative · entry 1

Kukekov Nickolay V. · CIK 0001827573 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 25,236 shares

Expires 2031-11-04

F2 · price: The reported transactions involved an amendment of an outstanding stock option, resulting in the deemed cancellation of the "old" stock option and the grant of a "replacement" stock option with a reduced exercise price.

F1 · derivative.exercise_date: The option vests and becomes exercisable to the extent of 12,618 shares on November 4, 2021 with the remaining 12,618 shares vesting quarterly in eight nearly equal installments beginning November 4, 2022 and continuing every three months thereafter until fully vested.

SEC source: 0001567619-22-019198 · doc1.xml · derivative · entry 15

Silva Francisco · CIK 0001527241 · Director · VP of Research and Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 42,059

Underlying: Common Stock · 42,059 shares

Expires 2031-11-04

F5 · price: The reported transactions involved an amendment of an outstanding stock option, resulting in the deemed cancellation of the "old" stock option and the grant of a "replacement" stock option with a reduced exercise price.

F4 · derivative.exercise_date: The option vests and becomes exercisable to the extent of 21,030 shares on November 4, 2021 with the remaining 21,029 shares vesting quarterly in eight nearly equal installments beginning on November 4, 2022.

SEC source: 0001567619-22-019198 · doc1.xml · derivative · entry 14

Silva Francisco · CIK 0001527241 · Director · VP of Research and Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 42,059 shares

Expires 2031-11-04

F5 · price: The reported transactions involved an amendment of an outstanding stock option, resulting in the deemed cancellation of the "old" stock option and the grant of a "replacement" stock option with a reduced exercise price.

F4 · derivative.exercise_date: The option vests and becomes exercisable to the extent of 21,030 shares on November 4, 2021 with the remaining 21,029 shares vesting quarterly in eight nearly equal installments beginning on November 4, 2022.

SEC source: 0001567619-22-019198 · doc1.xml · derivative · entry 13

Silva Francisco · CIK 0001527241 · Director · VP of Research and Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 293,479

Underlying: Common Stock · 293,479 shares

Expires 2031-03-18

F5 · price: The reported transactions involved an amendment of an outstanding stock option, resulting in the deemed cancellation of the "old" stock option and the grant of a "replacement" stock option with a reduced exercise price.

F3 · derivative.exercise_date: The option vests and becomes exercisable to the extent of 146,740 shares on March 18, 2021, 36,684 shares on November 4, 2021 and the remaining 110,055 shares in six nearly equal quarterly installments beginning December 18, 2021 and continuing every three months thereafter until fully vested.

SEC source: 0001567619-22-019198 · doc1.xml · derivative · entry 12

Silva Francisco · CIK 0001527241 · Director · VP of Research and Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 293,479 shares

Expires 2031-03-18

F5 · price: The reported transactions involved an amendment of an outstanding stock option, resulting in the deemed cancellation of the "old" stock option and the grant of a "replacement" stock option with a reduced exercise price.

F3 · derivative.exercise_date: The option vests and becomes exercisable to the extent of 146,740 shares on March 18, 2021, 36,684 shares on November 4, 2021 and the remaining 110,055 shares in six nearly equal quarterly installments beginning December 18, 2021 and continuing every three months thereafter until fully vested.

SEC source: 0001567619-22-019195 · doc1.xml · derivative · entry 3

Kristal Robert Eugene · CIK 0001893955 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,490

Underlying: Common Stock · 10,490 shares

Expires 2031-11-04

F2 · price: The reported transactions involved an amendment of an outstanding stock option, resulting in the deemed cancellation of the "old" stock option and the grant of a "replacement" stock option with a reduced exercise price.

F1 · derivative.exercise_date: The option vests and becomes exercisable in eight nearly-equal quarterly installments beginning on February 4, 2022 and continuing every three months thereafter until fully vested.

SEC source: 0001567619-22-019195 · doc1.xml · derivative · entry 2

Kristal Robert Eugene · CIK 0001893955 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 10,490 shares

Expires 2031-11-04

F2 · price: The reported transactions involved an amendment of an outstanding stock option, resulting in the deemed cancellation of the "old" stock option and the grant of a "replacement" stock option with a reduced exercise price.

F1 · derivative.exercise_date: The option vests and becomes exercisable in eight nearly-equal quarterly installments beginning on February 4, 2022 and continuing every three months thereafter until fully vested.

SEC source: 0001567619-22-019189 · doc1.xml · derivative · entry 2

Rosa David A · CIK 0001540354 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,490

Underlying: Common Stock · 10,490 shares

Expires 2031-11-04

F2 · price: The reported transactions involved an amendment of an outstanding stock option, resulting in the deemed cancellation of the "old" stock option and the grant of a "replacement" stock option with a reduced exercise price.

F1 · derivative.exercise_date: The option vests and becomes exercisable in eight nearly-equal, quarterly installments beginning on February 4, 2022 and continuing every three months thereafter until fully vested.

SEC source: 0001567619-22-019189 · doc1.xml · derivative · entry 1

Rosa David A · CIK 0001540354 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 10,490 shares

Expires 2031-11-04

F2 · price: The reported transactions involved an amendment of an outstanding stock option, resulting in the deemed cancellation of the "old" stock option and the grant of a "replacement" stock option with a reduced exercise price.

F1 · derivative.exercise_date: The option vests and becomes exercisable in eight nearly-equal, quarterly installments beginning on February 4, 2022 and continuing every three months thereafter until fully vested.

SEC source: 0001567619-22-019191 · doc1.xml · derivative · entry 2

Williams Patrick F. · CIK 0001562229 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,490

Underlying: Common Stock · 10,490 shares

Expires 2031-11-04

F2 · price: The reported transactions involved an amendment of an outstanding stock option, resulting in the deemed cancellation of the "old" stock option and the grant of a "replacement" stock option with a reduced exercise price.

F1 · derivative.exercise_date: The option vests and becomes exercisable in eight nearly-equal quarterly installments beginning on February 4, 2022 and continuing every three months thereafter until fully vested.

SEC source: 0001567619-22-019191 · doc1.xml · derivative · entry 1

Williams Patrick F. · CIK 0001562229 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 10,490 shares

Expires 2031-11-04

F2 · price: The reported transactions involved an amendment of an outstanding stock option, resulting in the deemed cancellation of the "old" stock option and the grant of a "replacement" stock option with a reduced exercise price.

F1 · derivative.exercise_date: The option vests and becomes exercisable in eight nearly-equal quarterly installments beginning on February 4, 2022 and continuing every three months thereafter until fully vested.

SEC source: 0001567619-22-019187 · doc1.xml · derivative · entry 5

ALSTODT LANCE · CIK 0001756228 · Director · President, CEO, COB

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 42,059

Underlying: Common Stock · 42,059 shares

Expires 2031-11-04

F4 · price: The reported transactions involved an amendment of an outstanding stock option, resulting in the deemed cancellation of the "old" stock option and the grant of a "replacement" stock option with a reduced exercise price.

F3 · derivative.exercise_date: The option vests and becomes exercisable to the extent of 21,030 shares on November 4, 2021 with the remaining 21,029 shares vesting quarterly in eight nearly equal installments beginning on November 4, 2022.

SEC source: 0001567619-22-019187 · doc1.xml · derivative · entry 4

ALSTODT LANCE · CIK 0001756228 · Director · President, CEO, COB

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 42,059 shares

Expires 2031-11-04

F4 · price: The reported transactions involved an amendment of an outstanding stock option, resulting in the deemed cancellation of the "old" stock option and the grant of a "replacement" stock option with a reduced exercise price.

F3 · derivative.exercise_date: The option vests and becomes exercisable to the extent of 21,030 shares on November 4, 2021 with the remaining 21,029 shares vesting quarterly in eight nearly equal installments beginning on November 4, 2022.

SEC source: 0001567619-22-019187 · doc1.xml · derivative · entry 3

ALSTODT LANCE · CIK 0001756228 · Director · President, CEO, COB

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 293,479

Underlying: Common Stock · 293,479 shares

Expires 2031-03-18

F4 · price: The reported transactions involved an amendment of an outstanding stock option, resulting in the deemed cancellation of the "old" stock option and the grant of a "replacement" stock option with a reduced exercise price.

F2 · derivative.exercise_date: The option vests and becomes exercisable to the extent of 146,740 shares on March 18, 2021, 36,684 shares on November 4, 2021 with the remaining 110,055 shares in six nearly equal quarterly installments beginning December 18, 2021 and continuing every three months thereafter until fully vested.

SEC source: 0001567619-22-019187 · doc1.xml · derivative · entry 2

ALSTODT LANCE · CIK 0001756228 · Director · President, CEO, COB

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 293,479 shares

Expires 2031-03-18

F4 · price: The reported transactions involved an amendment of an outstanding stock option, resulting in the deemed cancellation of the "old" stock option and the grant of a "replacement" stock option with a reduced exercise price.

F2 · derivative.exercise_date: The option vests and becomes exercisable to the extent of 146,740 shares on March 18, 2021, 36,684 shares on November 4, 2021 with the remaining 110,055 shares in six nearly equal quarterly installments beginning December 18, 2021 and continuing every three months thereafter until fully vested.

SEC source: 0001567619-22-018437 · doc1.xml · nonDerivative · entry 1

Silva Francisco · CIK 0001527241 · Director · VP of Research and Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 165,103

F1 · balance_after: Includes 104,045 shares received pursuant to unvested restricted stock unit grants. Such shares vest to the extent of 1,037 shares on each of October 18, 2022, December 18, 2022 and February 18, 2023, 1,036 shares on each of November 18, 2022 and January 18, 2023, 49,949 shares on March 18, 2023 and 48,913 shares on March 18, 2024.

SEC source: 0001567619-22-018424 · doc1.xml · nonDerivative · entry 1

Silva Francisco · CIK 0001527241 · Director · VP of Research and Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 164,378

F1 · price: This transaction was executed in multiple trades at prices ranging from $3.68 to $3.70 per share. The price reported above reflects the weighted average purchase price. The reporting person hereby undertakes to provide, upon request to the SEC staff, the issuer or a security holder of the issuer, full information regarding the number of shares and prices at which the transactions were effected.

F2 · balance_after: Includes 104,045 shares received pursuant to unvested restricted stock unit grants. Such shares vest to the extent of 1,037 shares on each of October 18, 2022, December 18, 2022 and February 18, 2023, 1,036 shares on each of November 18, 2022 and January 18, 2023, 49,949 shares on March 18, 2023 and 48,913 shares on March 18, 2024.

SEC source: 0001567619-22-017856 · doc1.xml · nonDerivative · entry 1

Broadrick Dale · CIK 0001677513 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 298,873

SEC source: 0001567619-22-017754 · doc1.xml · nonDerivative · entry 2

ALSTODT LANCE · CIK 0001756228 · Director · President, CEO, COB

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 182,921

F1 · balance_after: Includes 104,045 shares received pursuant to unvested restricted stock unit grants. Such shares vest to the extent of 1,037 shares on October 18, 2022, December 18, 2022 and February 18, 2023, 1,036 shares on November 18, 2022 and January 18, 2023, 49,949 shares on March 18, 2023 and 48,913 shares on March 18, 2024.

SEC source: 0001567619-22-017754 · doc1.xml · nonDerivative · entry 1

ALSTODT LANCE · CIK 0001756228 · Director · President, CEO, COB

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 182,821

F1 · balance_after: Includes 104,045 shares received pursuant to unvested restricted stock unit grants. Such shares vest to the extent of 1,037 shares on October 18, 2022, December 18, 2022 and February 18, 2023, 1,036 shares on November 18, 2022 and January 18, 2023, 49,949 shares on March 18, 2023 and 48,913 shares on March 18, 2024.

SEC source: 0001567619-22-017246 · doc1.xml · nonDerivative · entry 4

Silva Francisco · CIK 0001527241 · Director · VP of Research and Development

10b5-1 filing: Not disclosed

Ownership: Indirect · IRA

Disclosed balance after: 12,136

F4 · price: This transaction was executed in multiple trades at prices ranging from $3.28 to $3.35 per share. The price reported above reflects the weighted average purchase price. The reporting person hereby undertakes to provide, upon request to the SEC staff, the issuer or a security holder of the issuer, full information regarding the number of shares and prices at which the transactions were effected.

SEC source: 0001567619-22-017246 · doc1.xml · nonDerivative · entry 3

Silva Francisco · CIK 0001527241 · Director · VP of Research and Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 163,572

F3 · price: This transaction was executed in multiple trades at prices ranging from $3.21 to $3.2159 per share. The price reported above reflects the weighted average purchase price. The reporting person hereby undertakes to provide, upon request to the SEC staff, the issuer or a security holder of the issuer, full information regarding the number of shares and prices at which the transactions were effected.

F2 · balance_after: Includes 105,081 shares received pursuant to unvested restricted stock unit grants. Such shares vest to the extent of 1,036 shares on each of September 18, 2022, November 18, 2022 and January 18, 2023, 1,037 shares on each of October 18, 2022, December 18, 2022 and February 18, 2023, 49,949 shares on March 18, 2023 and 48,913 shares on March 18, 2024.

SEC source: 0001567619-22-017246 · doc1.xml · nonDerivative · entry 2

Silva Francisco · CIK 0001527241 · Director · VP of Research and Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 160,756

F2 · balance_after: Includes 105,081 shares received pursuant to unvested restricted stock unit grants. Such shares vest to the extent of 1,036 shares on each of September 18, 2022, November 18, 2022 and January 18, 2023, 1,037 shares on each of October 18, 2022, December 18, 2022 and February 18, 2023, 49,949 shares on March 18, 2023 and 48,913 shares on March 18, 2024.

SEC source: 0001567619-22-017246 · doc1.xml · nonDerivative · entry 1

Silva Francisco · CIK 0001527241 · Director · VP of Research and Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 158,156

F1 · price: Represents transaction inadvertently effected by the reporting person. This transaction was executed in multiple trades at prices ranging from $3.33 to $3.45 per share. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide, upon request to the SEC staff, the issuer or a security holder of the issuer, full information regarding the number of shares and prices at which the transactions were effected.

F2 · balance_after: Includes 105,081 shares received pursuant to unvested restricted stock unit grants. Such shares vest to the extent of 1,036 shares on each of September 18, 2022, November 18, 2022 and January 18, 2023, 1,037 shares on each of October 18, 2022, December 18, 2022 and February 18, 2023, 49,949 shares on March 18, 2023 and 48,913 shares on March 18, 2024.

SEC source: 0001567619-22-014051 · doc1.xml · nonDerivative · entry 3

Broadrick Dale · CIK 0001677513 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 298,573

SEC source: 0001567619-22-013928 · doc1.xml · nonDerivative · entry 1

ALSTODT LANCE · CIK 0001756228 · Director · President, CEO, COB

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 182,721

F1 · price: This transaction was executed in multiple trades at prices ranging from $2.90 to $2.97 per share. The price reported above reflects the weighted average purchase price. The reporting person hereby undertakes to provide, upon request to the SEC staff, the issuer or a security holder of the issuer, full information regarding the number of shares and prices at which the transactions were effected.

F2 · balance_after: Includes 107,154 shares received pursuant to unvested restricted stock unit grants. Such shares vest to the extent of 1,037 shares on August 18, 2022, October 18, 2022, December 18, 2022 and February 18, 2023, 1,036 shares on July 18, 2022, September 18, 2022, November 18, 2022 and January 18, 2023, 49,949 shares on March 18, 2023 and 48,913 shares on March 18, 2024.

SEC source: 0001567619-22-014051 · doc1.xml · nonDerivative · entry 2

Broadrick Dale · CIK 0001677513 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 298,373

F1 · price: This transaction was executed in multiple trades at prices ranging from $2.95 to $2.9799 per share. The price reported above reflects the weighted average purchase price. The reporting person hereby undertakes to provide, upon request to the SEC staff, the issuer or a security holder of the issuer, full information regarding the number of shares and prices at which the transactions were effected.

SEC source: 0001567619-22-014051 · doc1.xml · nonDerivative · entry 1

Broadrick Dale · CIK 0001677513 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 297,473