ARDX

SEC source: 0001567619-19-012993 · doc1.xml · nonDerivative · entry 1

GRAMMER ELIZABETH A · CIK 0001213041 · SVP, General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 130,284

F1 · balance_after: Includes 3,000 shares acquired under the Issuer's Employee Stock Purchase Plan on February 28, 2019.

SEC source: 0001567619-19-007106 · doc1.xml · derivative · entry 1

Block Geoffrey A. · CIK 0001770782 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 75,000

Underlying: Common Stock · 75,000 shares

Expires 2029-03-14

F1 · derivative.exercise_date: The option becomes exercisable as it vests and the shares subject to the option vest in 36 successive, equal monthly installments on each monthly anniversary of March 14, 2019, subject to the Reporting Person's continued employment or service relationship with the Issuer on each such vesting date.

SEC source: 0001567619-19-001444 · doc1.xml · derivative · entry 2

Rosenbaum David P. · CIK 0001611311 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 54,343

Underlying: Common Stock · 54,343 shares

Expires 2029-01-17

F1 · derivative.exercise_date: The option becomes exercisable as it vests and the shares subject to the option vest in 48 successive, equal monthly installments on each monthly anniversary of January 17, 2019, subject to the Reporting Person's continued employment or service relationship with the Issuer on each such vesting date.

F2 · ownership.nature: The options are directly held by the Reporting Person's wife.

SEC source: 0001567619-19-001444 · doc1.xml · derivative · entry 1

Rosenbaum David P. · CIK 0001611311 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 120,000

Underlying: Common Stock · 120,000 shares

Expires 2029-01-17

F1 · derivative.exercise_date: The option becomes exercisable as it vests and the shares subject to the option vest in 48 successive, equal monthly installments on each monthly anniversary of January 17, 2019, subject to the Reporting Person's continued employment or service relationship with the Issuer on each such vesting date.

SEC source: 0001567619-19-001442 · doc1.xml · derivative · entry 1

Kaufmann Mark · CIK 0001611184 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 120,000

Underlying: Common Stock · 120,000 shares

Expires 2029-01-17

F1 · derivative.exercise_date: The option becomes exercisable as it vests and the shares subject to the option vest in 48 successive, equal monthly installments on each monthly anniversary of January 17, 2019, subject to the Reporting Person's continued employment or service relationship with the Issuer on each such vesting date.

SEC source: 0001567619-19-001443 · doc1.xml · derivative · entry 1

GRAMMER ELIZABETH A · CIK 0001213041 · EVP, General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 120,000

Underlying: Common Stock · 120,000 shares

Expires 2029-01-17

F1 · derivative.exercise_date: The option becomes exercisable as it vests and the shares subject to the option vest in 48 successive, equal monthly installments on each monthly anniversary of January 17, 2019, subject to the Reporting Person's continued employment or service relationship with the Issuer on each such vesting date.

SEC source: 0001567619-19-001441 · doc1.xml · derivative · entry 1

RAAB MICHAEL · CIK 0001321402 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 455,000

Underlying: Common Stock · 455,000 shares

Expires 2029-01-17

F1 · derivative.exercise_date: The option becomes exercisable as it vests and the shares subject to the option vest in 48 successive, equal monthly installments on each monthly anniversary of January 17, 2019, subject to the Reporting Person's continued employment or service relationship with the Issuer on each such vesting date.

SEC source: 0001567619-19-000643 · doc1.xml · nonDerivative · entry 2

Rosenbaum David P. · CIK 0001611311 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 18,029

F1 · kind: Pursuant to an automatic sell-to-cover imposed by the terms of the initial grant of the restricted stock units ("RSUs") awards, the shares were sold upon the vesting of the RSUs solely to cover applicable withholding taxes.

F3 · price: This transaction was executed in multiple trades in prices ranging from $1.70 to $1.7326, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

F4 · ownership.nature: The shares are directly held by the Reporting Person's wife.

SEC source: 0001567619-19-000643 · doc1.xml · nonDerivative · entry 1

Rosenbaum David P. · CIK 0001611311 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 160,027

F1 · kind: Pursuant to an automatic sell-to-cover imposed by the terms of the initial grant of the restricted stock units ("RSUs") awards, the shares were sold upon the vesting of the RSUs solely to cover applicable withholding taxes.

F2 · price: This transaction was executed in multiple trades in prices ranging from $1.70 to $1.7335, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

SEC source: 0001567619-19-000642 · doc1.xml · nonDerivative · entry 1

RAAB MICHAEL · CIK 0001321402 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 261,409

F1 · kind: Pursuant to an automatic sell-to-cover imposed by the terms of the initial grant of the restricted stock units ("RSUs") awards, the shares were sold upon the vesting of the RSUs solely to cover applicable withholding taxes.

F2 · price: This transaction was executed in multiple trades in prices ranging from $1.70 to $1.7256, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

F3 · balance_after: Shares held after the transaction reflects the prior transfer of an aggregate of 11,446, previously held directly by the Reporting Person, into the Reporting Person's trust.

SEC source: 0001567619-19-000641 · doc1.xml · nonDerivative · entry 1

Kaufmann Mark · CIK 0001611184 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 139,933

F1 · kind: Pursuant to an automatic sell-to-cover imposed by the terms of the initial grant of the restricted stock units ("RSUs") awards, the shares were sold upon the vesting of the RSUs solely to cover applicable withholding taxes.

F2 · price: This transaction was executed in multiple trades in prices ranging from $1.70 to $1.7305, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

SEC source: 0001567619-19-000640 · doc1.xml · nonDerivative · entry 1

GRAMMER ELIZABETH A · CIK 0001213041 · EVP, General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 129,284

F1 · kind: Pursuant to an automatic sell-to-cover imposed by the terms of the initial grant of the restricted stock units ("RSUs") awards, the shares were sold upon the vesting of the RSUs solely to cover applicable withholding taxes.

F2 · price: This transaction was executed in multiple trades in prices ranging from $1.70 to $1.7261, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

SEC source: 0001567619-18-006496 · doc1.xml · nonDerivative · entry 5

GRAMMER ELIZABETH A · CIK 0001213041 · EVP, General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 134,204

F3 · kind: Pursuant to an automatic sell-to-cover imposed by the terms of the initial grant of the restricted stock units ("RSUs") awards, the shares were sold upon the vesting of the RSUs solely to cover applicable withholding taxes.

F4 · price: This transaction was executed in multiple trades in prices ranging from $2.8062 to $2.84, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

SEC source: 0001567619-18-006487 · doc1.xml · nonDerivative · entry 1

RAAB MICHAEL · CIK 0001321402 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 292,499

F1 · kind: Pursuant to an automatic sell-to-cover imposed by the terms of the initial grant of the restricted stock units ("RSUs") awards, the shares were sold upon the vesting of the RSUs solely to cover applicable withholding taxes.

F2 · price: This transaction was executed in multiple trades in prices ranging from $2.8022 to $2.84, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

SEC source: 0001567619-18-006486 · doc1.xml · nonDerivative · entry 1

Kaufmann Mark · CIK 0001611184 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 146,489

F1 · kind: Pursuant to an automatic sell-to-cover imposed by the terms of the initial grant of the restricted stock units ("RSUs") awards, the shares were sold upon the vesting of the RSUs solely to cover applicable withholding taxes.

F2 · price: This transaction was executed in multiple trades in prices ranging from $2.81 to $2.84, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

F3 · balance_after: Includes 1,642 shares acquired under the Issuer's Employee Stock Purchase Plan on August 31, 2018.

SEC source: 0001567619-18-006485 · doc1.xml · nonDerivative · entry 1

Rosenbaum David P. · CIK 0001611311 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 165,612

F1 · kind: Pursuant to an automatic sell-to-cover imposed by the terms of the initial grant of the restricted stock units ("RSUs") awards, the shares were sold upon the vesting of the RSUs solely to cover applicable withholding taxes.

F2 · price: This transaction was executed in multiple trades in prices ranging from $2.81 to $2.84, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

F3 · balance_after: Includes 2,627 shares acquired under the Issuer's Employee Stock Purchase Plan on August 31, 2018.

SEC source: 0001209191-18-058303 · doc4.xml · nonDerivative · entry 1

SANDELL SCOTT D · CIK 0001237289 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See Note 2

Disclosed balance after: 0

F1 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $2.985 to $2.981, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote (1) to this Form 4.

F2 · ownership.nature: The securities are directly held by Rising River Partners, L.P. The Reporting Person disclaims beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities of the Issuer held by Rising River Partners, L.P. in which the Reporting Person has no pecuniary interest.

SEC source: 0001567619-18-006496 · doc1.xml · nonDerivative · entry 4

GRAMMER ELIZABETH A · CIK 0001213041 · EVP, General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 140,743

SEC source: 0001567619-18-006496 · doc1.xml · nonDerivative · entry 3

GRAMMER ELIZABETH A · CIK 0001213041 · EVP, General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 141,743

SEC source: 0001567619-18-006496 · doc1.xml · nonDerivative · entry 2

GRAMMER ELIZABETH A · CIK 0001213041 · EVP, General Counsel

10b5-1 filing: Not disclosed

Ownership: Indirect · By son

Disclosed balance after: 1,000

F1 · kind: This transaction involved a gift of securities by the Reporting Person to her son, who shares Reporting Person's household. The Reporting Person disclaims beneficial ownership of the shares held by her son, and this report should not be deemed an admission that the Reporting Person is the beneficial owner of her son's shares for purposes of Section 16 or for any other purpose.

SEC source: 0001567619-18-006496 · doc1.xml · nonDerivative · entry 1

GRAMMER ELIZABETH A · CIK 0001213041 · EVP, General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 142,743

F1 · kind: This transaction involved a gift of securities by the Reporting Person to her son, who shares Reporting Person's household. The Reporting Person disclaims beneficial ownership of the shares held by her son, and this report should not be deemed an admission that the Reporting Person is the beneficial owner of her son's shares for purposes of Section 16 or for any other purpose.

F2 · balance_after: Includes 2,463 shares acquired under the Issuer's Employee Stock Purchase Plan on August 31, 2018.

SEC source: 0001140361-18-034303 · doc1.xml · derivative · entry 4

RAAB MICHAEL · CIK 0001321402 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 185,000

Underlying: Common Stock · 185,000 shares

Expires 2028-07-26

F5 · derivative.exercise_date: The option becomes exercisable as it vests and the shares subject to the option vest with respect to 1/48 of the shares subject thereto on each monthly anniversary of July 26, 2018, subject to the Reporting Person's continued employment or service relationship with the Issuer on each such vesting date.

SEC source: 0001140361-18-034303 · doc1.xml · nonDerivative · entry 1

RAAB MICHAEL · CIK 0001321402 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 299,038

F1 · shares: Restricted stock units ("RSUs"). The Reporting Person is entitled to receive one (1) share of Common Stock for each one (1) RSU upon the vesting thereof.

SEC source: 0001140361-18-034304 · doc1.xml · derivative · entry 2

GRAMMER ELIZABETH A · CIK 0001213041 · SVP, General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 54,730

Underlying: Common Stock · 54,730 shares

Expires 2028-07-26

F3 · derivative.exercise_date: The option becomes exercisable as it vests and the shares subject to the option vest with respect to 1/48 of the shares subject thereto on each monthly anniversary of July 26, 2018, subject to the Reporting Person's continued employment or service relationship with the Issuer on each such vesting date.

SEC source: 0001140361-18-034304 · doc1.xml · nonDerivative · entry 1

GRAMMER ELIZABETH A · CIK 0001213041 · SVP, General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 141,280

F1 · shares: Restricted stock units ("RSUs"). The Reporting Person is entitled to receive one (1) share of Common Stock for each one (1) RSU upon the vesting thereof.

F2 · balance_after: Includes an aggregate of 2,386 shares acquired under the Issuer's Employee Stock Purchase Plan on August 31, 2017 and February 28, 2018.

SEC source: 0001140361-18-034302 · doc1.xml · derivative · entry 2

Kaufmann Mark · CIK 0001611184 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 54,730

Underlying: Common Stock · 54,730 shares

Expires 2028-07-26

F3 · derivative.exercise_date: The option becomes exercisable as it vests and the shares subject to the option vest with respect to 1/48 of the shares subject thereto on each monthly anniversary of July 26, 2018, subject to the Reporting Person's continued employment or service relationship with the Issuer on each such vesting date.

SEC source: 0001140361-18-034302 · doc1.xml · nonDerivative · entry 1

Kaufmann Mark · CIK 0001611184 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 151,386

F1 · shares: Restricted stock units ("RSUs"). The Reporting Person is entitled to receive one (1) share of Common Stock for each one (1) RSU upon the vesting thereof.

F2 · balance_after: Includes (i) an aggregate of 2,708 shares acquired under the Issuer's Employee Stock Purchase Plan on August 31, 2017 and February 28, 2018, and (ii) 90 shares which were inadvertently omitted from the Reporting Person's Form 4 filed on August 11, 2017.

SEC source: 0001140361-18-034301 · doc1.xml · derivative · entry 5

Rosenbaum David P. · CIK 0001611311 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 8,220

Underlying: Common Stock · 8,220 shares

Expires 2028-07-26

F6 · derivative.exercise_date: The option becomes exercisable as it vests and the shares subject to the option vest with respect to 1/48 of the shares subject thereto on each monthly anniversary of July 26, 2018, subject to the Reporting Person's continued employment or service relationship with the Issuer on each such vesting date.

F4 · ownership.nature: The shares are directly held by the Reporting Person's wife.

SEC source: 0001140361-18-034301 · doc1.xml · derivative · entry 4

Rosenbaum David P. · CIK 0001611311 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 54,730

Underlying: Common Stock · 54,730 shares

Expires 2028-07-26

F6 · derivative.exercise_date: The option becomes exercisable as it vests and the shares subject to the option vest with respect to 1/48 of the shares subject thereto on each monthly anniversary of July 26, 2018, subject to the Reporting Person's continued employment or service relationship with the Issuer on each such vesting date.

SEC source: 0001140361-18-034301 · doc1.xml · nonDerivative · entry 2

Rosenbaum David P. · CIK 0001611311 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 17,045

F1 · shares: Restricted stock units ("RSUs"). The Reporting Person is entitled to receive one (1) share of Common Stock for each one (1) RSU upon the vesting thereof.

F3 · balance_after: Includes 3,000 shares acquired by the Reporting Person's spouse under the ESPP on February 28, 2018.

F4 · ownership.nature: The shares are directly held by the Reporting Person's wife.

SEC source: 0001140361-18-034301 · doc1.xml · nonDerivative · entry 1

Rosenbaum David P. · CIK 0001611311 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 168,555

F1 · shares: Restricted stock units ("RSUs"). The Reporting Person is entitled to receive one (1) share of Common Stock for each one (1) RSU upon the vesting thereof.

F2 · balance_after: Includes 1,644 shares acquired under the Issuer's Employee Stock Purchase Plan (the "ESPP") on February 28, 2018.

SEC source: 0001140361-18-028858 · doc1.xml · derivative · entry 1

RINGOLD GORDON · CIK 0001101713 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 15,000 shares

Expires 2028-06-13

F1 · shares: The option was issued pursuant to the Issuer's Non-Employee Director Compensation Program.

F2 · derivative.exercise_date: The option vests with respect to 1/12th of the shares subject thereto on each monthly anniversary of the grant date, which vesting will accelerate in full on the date of the next annual stockholder's meeting to the extent unvested as of such date, subject to continued service through each applicable vesting date.

SEC source: 0001140361-18-028859 · doc1.xml · nonDerivative · entry 1

Lundberg Jan M · CIK 0001480120 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,786

F1 · shares: The shares were issued pursuant to the Issuer's Non-Employee Director Compensation Program. The Reporting Person elected to receive stock in lieu of cash as permitted under the program.

SEC source: 0001209191-18-038207 · doc4.xml · derivative · entry 4

MOTT DAVID M · CIK 0001219871 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 15,000 shares

Expires 2028-06-13

F4 · shares: The option was issued pursuant to the Issuer's Non-Employee Director Compensation Program.

F5 · derivative.exercise_date: The option vests with respect to 1/12th of the shares subject thereto on each monthly anniversary of the grant date, which vesting will accelerate in full on the date of the next annual stockholder's meeting to the extent unvested as of such date, subject to continued service through each applicable vesting date.

SEC source: 0001209191-18-038207 · doc4.xml · nonDerivative · entry 3

MOTT DAVID M · CIK 0001219871 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 54,720

F3 · shares: The shares were issued pursuant to the Issuer's Non-Employee Director Compensation Program. The Reporting Person elected to receive stock in lieu of cash as permitted under the Program.

SEC source: 0001140361-18-028863 · doc1.xml · derivative · entry 2

Bertrand William C JR · CIK 0001291937 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 15,000 shares

Expires 2028-06-13

F2 · shares: The option was issued pursuant to the Issuer's Non-Employee Director Compensation Program.

F3 · derivative.exercise_date: The option vests with respect to 1/12th of the shares subject thereto on each monthly anniversary of the grant date, which vesting will accelerate in full on the date of the next annual stockholder's meeting to the extent unvested as of such date, subject to continued service through each applicable vesting date.

SEC source: 0001140361-18-028863 · doc1.xml · nonDerivative · entry 1

Bertrand William C JR · CIK 0001291937 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,887

F1 · shares: The shares were issued pursuant to the Issuer's Non-Employee Director Compensation Program. The Reporting Person elected to receive stock in lieu of cash as permitted under the program.

SEC source: 0001140361-18-028865 · doc1.xml · derivative · entry 2

Jenkins Annalisa · CIK 0001639481 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 15,000 shares

Expires 2028-06-13

F2 · shares: The option was issued pursuant to the Issuer's Non-Employee Director Compensation Program.

F3 · derivative.exercise_date: The option vests with respect to 1/12th of the shares subject thereto on each monthly anniversary of the grant date, which vesting will accelerate in full on the date of the next annual stockholder's meeting to the extent unvested as of such date, subject to continued service through each applicable vesting date.

SEC source: 0001140361-18-028865 · doc1.xml · nonDerivative · entry 1

Jenkins Annalisa · CIK 0001639481 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,399

F1 · shares: The shares were issued pursuant to the Issuer's Non-Employee Director Compensation Program. The Reporting Person elected to receive stock in lieu of cash as permitted under the program.

SEC source: 0001140361-18-028862 · doc1.xml · derivative · entry 1

Bazemore Robert B · CIK 0001620152 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 15,000 shares

Expires 2028-06-13

F1 · shares: The option was issued pursuant to the Issuer's Non-Employee Director Compensation Program.

F2 · derivative.exercise_date: The option vests with respect to 1/12th of the shares subject thereto on each monthly anniversary of the grant date, which vesting will accelerate in full on the date of the next annual stockholder's meeting to the extent unvested as of such date, subject to continued service through each applicable vesting date.

SEC source: 0001140361-18-028861 · doc1.xml · derivative · entry 2

Rodgers Richard J · CIK 0001313397 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 15,000 shares

Expires 2028-06-13

F2 · shares: The option was issued pursuant to the Issuer's Non-Employee Director Compensation Program.

F3 · derivative.exercise_date: The option vests with respect to 1/12th of the shares subject thereto on each monthly anniversary of the grant date, which vesting will accelerate in full on the date of the next annual stockholder's meeting to the extent unvested as of such date, subject to continued service through each applicable vesting date.

SEC source: 0001140361-18-028861 · doc1.xml · nonDerivative · entry 1

Rodgers Richard J · CIK 0001313397 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 43,742

F1 · shares: The shares were issued pursuant to the Issuer's Non-Employee Director Compensation Program. The Reporting Person elected to receive stock in lieu of cash as permitted under the program.

SEC source: 0001140361-18-026883 · doc1.xml · nonDerivative · entry 1

RINGOLD GORDON · CIK 0001101713 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 25,000

F1 · ownership.nature: The shares are held directly by the Barthold Family Foundation, for which the Reporting Person serves as a Trustee.

SEC source: 0001209191-18-034173 · doc4.xml · nonDerivative · entry 3

BARRIS PETER J · CIK 0001005561 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See Note 3

Disclosed balance after: 3,082,186

F3 · ownership.nature: The Reporting Person is a manager of NEA 15 GP which is the sole general partner of NEA Partners 15-OF, L.P. ("NEA Partners 15-OF"). NEA Partners 15-OF is the sole general partner of NEA 15 Opportunity Fund, L. P. ("NEA Opportunity 15"), the direct beneficial owner of the securities. The Reporting Person disclaims beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA Opportunity 15 in which the Reporting Person has no pecuniary interest.

SEC source: 0001209191-18-034173 · doc4.xml · nonDerivative · entry 2

BARRIS PETER J · CIK 0001005561 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See Note 2

Disclosed balance after: 3,082,186

F2 · ownership.nature: The Reporting Person is a manager of NEA 15 GP, LLC, ("NEA 15 GP") which is the sole general partner of NEA Partners 15, L.P. ("NEA Partners 15"). NEA Partners 15 is the sole general partner of New Enterprise Associates 15, L. P. ("NEA 15"), the direct beneficial owner of the securities. The Reporting Person disclaims beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA 15 in which the Reporting Person has no pecuniary interest.

SEC source: 0001209191-18-034173 · doc4.xml · nonDerivative · entry 1

BARRIS PETER J · CIK 0001005561 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See Note 1

Disclosed balance after: 9,169,210

F1 · ownership.nature: The Reporting Person is a manager of NEA 12 GP, LLC, ("NEA 12 GP") which is the sole general partner of NEA Partners 12, Limited Partnership ("NEA Partners 12"). NEA Partners 12 is the sole general partner of New Enterprise Associates 12, Limited Partnership ("NEA 12"), the direct beneficial owner of the securities. The Reporting Person disclaims beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA 12 in which the Reporting Person has no pecuniary interest.

SEC source: 0001209191-18-034182 · doc4.xml · nonDerivative · entry 2

Viswanathan Ravi · CIK 0001479386 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See Note 2

Disclosed balance after: 3,082,186

F2 · ownership.nature: The Reporting Person is a manager of NEA 15 GP which is the sole general partner of NEA Partners 15-OF, L.P. ("NEA Partners 15-OF"). NEA Partners 15-OF is the sole general partner of NEA 15 Opportunity Fund, L. P. ("NEA Opportunity 15"), the direct beneficial owner of the securities. The Reporting Person disclaims beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA Opportunity 15 in which the Reporting Person has no pecuniary interest.

SEC source: 0001209191-18-034182 · doc4.xml · nonDerivative · entry 1

Viswanathan Ravi · CIK 0001479386 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See Note 1

Disclosed balance after: 3,082,186

F1 · ownership.nature: The Reporting Person is a manager of NEA 15 GP, LLC, ("NEA 15 GP") which is the sole general partner of NEA Partners 15, L.P. ("NEA Partners 15"). NEA Partners 15 is the sole general partner of New Enterprise Associates 15, L. P. ("NEA 15"), the direct beneficial owner of the securities. The Reporting Person disclaims beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA 15 in which the Reporting Person has no pecuniary interest.

SEC source: 0001209191-18-034180 · doc4.xml · nonDerivative · entry 3

SANDELL SCOTT D · CIK 0001237289 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See Note 3

Disclosed balance after: 3,082,186

F3 · ownership.nature: The Reporting Person is a manager of NEA 15 GP which is the sole general partner of NEA Partners 15-OF, L.P. ("NEA Partners 15-OF"). NEA Partners 15-OF is the sole general partner of NEA 15 Opportunity Fund, L. P. ("NEA Opportunity 15"), the direct beneficial owner of the securities. The Reporting Person disclaims beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA Opportunity 15 in which the Reporting Person has no pecuniary interest.

SEC source: 0001209191-18-034180 · doc4.xml · nonDerivative · entry 2

SANDELL SCOTT D · CIK 0001237289 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See Note 2

Disclosed balance after: 3,082,186

F2 · ownership.nature: The Reporting Person is a manager of NEA 15 GP, LLC, ("NEA 15 GP") which is the sole general partner of NEA Partners 15, L.P. ("NEA Partners 15"). NEA Partners 15 is the sole general partner of New Enterprise Associates 15, L. P. ("NEA 15"), the direct beneficial owner of the securities. The Reporting Person disclaims beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA 15 in which the Reporting Person has no pecuniary interest.