ARDX

SEC source: 0001567619-21-010920 · doc1.xml · nonDerivative · entry 2

GRAMMER ELIZABETH A · CIK 0001213041 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 102,912

F1 · kind: Pursuant to an automatic sell-to-cover imposed by the terms of the initial grant of the restricted stock units ("RSUs") awards, the shares were sold upon the vesting of the RSUs solely to cover applicable withholding taxes.

SEC source: 0001567619-21-007839 · doc1.xml · nonDerivative · entry 2

Blanks Robert · CIK 0001815433 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 107,566

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person on June 19, 2020.

SEC source: 0001567619-21-007839 · doc1.xml · nonDerivative · entry 1

Blanks Robert · CIK 0001815433 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 109,392

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person on June 19, 2020.

SEC source: 0001567619-21-007840 · doc1.xml · nonDerivative · entry 1

Rosenbaum David P. · CIK 0001611311 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 160,047

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person on June 26, 2020.

SEC source: 0001567619-21-006314 · doc1.xml · derivative · entry 1

Bhanji Muna · CIK 0001846905 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 63,687

Underlying: Common Stock · 63,687 shares

Expires 2031-03-11

F1 · derivative.exercise_date: The shares subject to the option vest in 36 successive, equal monthly installments on each monthly anniversary of March 11, 2021, subject to the Reporting Person's continued employment or service relationship with the Issuer on each such vesting date.

SEC source: 0001567619-21-004775 · doc1.xml · nonDerivative · entry 1

Rodriguez Susan · CIK 0001812511 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,914

F1 · kind: Pursuant to an automatic sell-to-cover imposed by the terms of the initial grant of the restricted stock units ("RSUs") awards, the shares were sold upon the vesting of the RSUs solely to cover applicable withholding taxes.

SEC source: 0001567619-21-004785 · doc1.xml · nonDerivative · entry 1

Blanks Robert · CIK 0001815433 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 112,729

F1 · kind: Pursuant to an automatic sell-to-cover imposed by the terms of the initial grant of the restricted stock units ("RSUs") awards, the shares were sold upon the vesting of the RSUs solely to cover applicable withholding taxes.

SEC source: 0001567619-21-004769 · doc1.xml · nonDerivative · entry 1

Renz Justin A · CIK 0001466562 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,290

F1 · kind: Pursuant to an automatic sell-to-cover imposed by the terms of the initial grant of the restricted stock units ("RSUs") awards, the shares were sold upon the vesting of the RSUs solely to cover applicable withholding taxes.

SEC source: 0001567619-21-004776 · doc1.xml · nonDerivative · entry 1

Jacobs Jeffrey W · CIK 0001611193 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 124,772

F1 · kind: Pursuant to an automatic sell-to-cover imposed by the terms of the initial grant of the restricted stock units ("RSUs") awards, the shares were sold upon the vesting of the RSUs solely to cover applicable withholding taxes.

F1 · shares: Pursuant to an automatic sell-to-cover imposed by the terms of the initial grant of the restricted stock units ("RSUs") awards, the shares were sold upon the vesting of the RSUs solely to cover applicable withholding taxes.

SEC source: 0001567619-21-004773 · doc1.xml · nonDerivative · entry 1

RAAB MICHAEL · CIK 0001321402 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 217,288

F1 · kind: Pursuant to an automatic sell-to-cover imposed by the terms of the initial grant of the restricted stock units ("RSUs") awards, the shares were sold upon the vesting of the RSUs solely to cover applicable withholding taxes.

SEC source: 0001567619-21-004772 · doc1.xml · nonDerivative · entry 2

Rosenbaum David P. · CIK 0001611311 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · By Wife

Disclosed balance after: 29,969

F1 · kind: Pursuant to an automatic sell-to-cover imposed by the terms of the initial grant of the restricted stock units ("RSUs") awards, the shares were sold upon the vesting of the RSUs solely to cover applicable withholding taxes.

F2 · ownership.nature: The shares are directly held by the Reporting Person's wife.

SEC source: 0001567619-21-004772 · doc1.xml · nonDerivative · entry 1

Rosenbaum David P. · CIK 0001611311 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 165,047

F1 · kind: Pursuant to an automatic sell-to-cover imposed by the terms of the initial grant of the restricted stock units ("RSUs") awards, the shares were sold upon the vesting of the RSUs solely to cover applicable withholding taxes.

SEC source: 0001567619-21-004768 · doc1.xml · nonDerivative · entry 2

GRAMMER ELIZABETH A · CIK 0001213041 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 103,420

F1 · kind: Pursuant to an automatic sell-to-cover imposed by the terms of the initial grant of the restricted stock units ("RSUs") awards, the shares were sold upon the vesting of the RSUs solely to cover applicable withholding taxes.

SEC source: 0001567619-21-000764 · doc1.xml · derivative · entry 2

Rodriguez Susan · CIK 0001812511 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 146,755

Underlying: Common Stock · 146,755 shares

Expires 2031-01-05

F2 · derivative.exercise_date: The option becomes exercisable as it vests and the shares subject to the option vest in 48 successive, equal monthly installments on each monthly anniversary of January 5, 2021, subject to the Reporting Person's continued employment or service relationship with the Issuer on each such vesting date.

SEC source: 0001567619-21-000764 · doc1.xml · nonDerivative · entry 1

Rodriguez Susan · CIK 0001812511 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 46,525

F1 · shares: Restricted stock units ("RSUs"). The Reporting Person is entitled to receive one (1) shares of Common Stock for each one (1) RSU upon the vesting thereof.

SEC source: 0001567619-21-000765 · doc1.xml · derivative · entry 2

Blanks Robert · CIK 0001815433 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 146,755

Underlying: Common Stock · 146,755 shares

Expires 2031-01-05

F2 · derivative.exercise_date: The option becomes exercisable as it vests and the shares subject to the option vest in 48 successive, equal monthly installments on each monthly anniversary of January 5, 2021, subject to the Reporting Person's continued employment or service relationship with the Issuer on each such vesting date.

SEC source: 0001567619-21-000765 · doc1.xml · nonDerivative · entry 1

Blanks Robert · CIK 0001815433 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 113,322

F1 · shares: Restricted stock units ("RSUs"). The Reporting Person is entitled to receive one (1) shares of Common Stock for each one (1) RSU upon the vesting thereof.

SEC source: 0001567619-21-000768 · doc1.xml · derivative · entry 2

Renz Justin A · CIK 0001466562 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 146,755

Underlying: Common Stock · 146,755 shares

Expires 2031-01-05

F2 · derivative.exercise_date: The option becomes exercisable as it vests and the shares subject to the option vest in 48 successive, equal monthly installments on each monthly anniversary of January 5, 2021, subject to the Reporting Person's continued employment or service relationship with the Issuer on each such vesting date.

SEC source: 0001567619-21-000768 · doc1.xml · nonDerivative · entry 1

Renz Justin A · CIK 0001466562 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,898

F1 · shares: Restricted stock units ("RSUs"). The Reporting Person is entitled to receive one (1) shares of Common Stock for each one (1) RSU upon the vesting thereof.

SEC source: 0001567619-21-000771 · doc1.xml · derivative · entry 5

Rosenbaum David P. · CIK 0001611311 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · By Wife

Disclosed balance after: 37,500

Underlying: Common Stock · 37,500 shares

Expires 2031-01-05

F4 · derivative.exercise_date: The option becomes exercisable as it vests and the shares subject to the option vest in 48 successive, equal monthly installments on each monthly anniversary of January 5, 2021, subject to the Reporting Person's continued employment or service relationship with the Issuer on each such vesting date.

F2 · ownership.nature: The shares are directly held by the Reporting Person's wife.

SEC source: 0001567619-21-000771 · doc1.xml · derivative · entry 4

Rosenbaum David P. · CIK 0001611311 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 146,755

Underlying: Common Stock · 146,755 shares

Expires 2031-01-05

F4 · derivative.exercise_date: The option becomes exercisable as it vests and the shares subject to the option vest in 48 successive, equal monthly installments on each monthly anniversary of January 5, 2021, subject to the Reporting Person's continued employment or service relationship with the Issuer on each such vesting date.

SEC source: 0001567619-21-000771 · doc1.xml · nonDerivative · entry 2

Rosenbaum David P. · CIK 0001611311 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · By Wife

Disclosed balance after: 30,162

F1 · shares: Restricted stock units ("RSUs"). The Reporting Person is entitled to receive one (1) shares of Common Stock for each one (1) RSU upon the vesting thereof.

F2 · ownership.nature: The shares are directly held by the Reporting Person's wife.

SEC source: 0001567619-21-000771 · doc1.xml · nonDerivative · entry 1

Rosenbaum David P. · CIK 0001611311 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 165,659

F1 · shares: Restricted stock units ("RSUs"). The Reporting Person is entitled to receive one (1) shares of Common Stock for each one (1) RSU upon the vesting thereof.

SEC source: 0001567619-21-000767 · doc1.xml · derivative · entry 4

RAAB MICHAEL · CIK 0001321402 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 517,959

Underlying: Common Stock · 517,959 shares

Expires 2031-01-05

F4 · derivative.exercise_date: The option becomes exercisable as it vests and the shares subject to the option vest in 48 successive, equal monthly installments on each monthly anniversary of January 5, 2021, subject to the Reporting Person's continued employment or service relationship with the Issuer on each such vesting date.

SEC source: 0001567619-21-000767 · doc1.xml · nonDerivative · entry 1

RAAB MICHAEL · CIK 0001321402 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 219,822

F1 · shares: Restricted stock units ("RSUs"). The Reporting Person is entitled to receive one (1) shares of Common Stock for each one (1) RSU upon the vesting thereof.

SEC source: 0001567619-21-000766 · doc1.xml · derivative · entry 2

Jacobs Jeffrey W · CIK 0001611193 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 146,755

Underlying: Common Stock · 146,755 shares

Expires 2031-01-05

F2 · derivative.exercise_date: The option becomes exercisable as it vests and the shares subject to the option vest in 48 successive, equal monthly installments on each monthly anniversary of January 5, 2021, subject to the Reporting Person's continued employment or service relationship with the Issuer on each such vesting date.

SEC source: 0001567619-21-000766 · doc1.xml · nonDerivative · entry 1

Jacobs Jeffrey W · CIK 0001611193 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 125,474

F1 · shares: Restricted stock units ("RSUs"). The Reporting Person is entitled to receive one (1) shares of Common Stock for each one (1) RSU upon the vesting thereof.

SEC source: 0001567619-21-000763 · doc1.xml · derivative · entry 6

GRAMMER ELIZABETH A · CIK 0001213041 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 146,755

Underlying: Common Stock · 146,755 shares

Expires 2031-01-05

F3 · derivative.exercise_date: The option becomes exercisable as it vests and the shares subject to the option vest in 48 successive, equal monthly installments on each monthly anniversary of January 5, 2021, subject to the Reporting Person's continued employment or service relationship with the Issuer on each such vesting date.

SEC source: 0001567619-21-000763 · doc1.xml · nonDerivative · entry 5

GRAMMER ELIZABETH A · CIK 0001213041 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 103,924

F2 · shares: Restricted stock units ("RSUs"). The Reporting Person is entitled to receive one (1) shares of Common Stock for each one (1) RSU upon the vesting thereof.

SEC source: 0001567619-20-021489 · doc1.xml · nonDerivative · entry 1

Jacobs Jeffrey W · CIK 0001611193 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 92,862

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person on November 17, 2020.

F2 · price: This transaction was executed in multiple trades in prices ranging from $6.76 to $7.04, inclusive. The price reported in Column 4 above reflects the weighted average sales price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

SEC source: 0001567619-21-000763 · doc1.xml · nonDerivative · entry 4

GRAMMER ELIZABETH A · CIK 0001213041 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Indirect · By Son

Disclosed balance after: 2,971

F1 · shares: This transaction involved a gift of securities by the Reporting Person to her son, who shares Reporting Person's household. The Reporting Person disclaims beneficial ownership of the shares held by her son, and this report should not be deemed an admission that the Reporting Person is the beneficial owner of her son's shares for purposes of Section 16 or for any other purpose.

SEC source: 0001567619-21-000763 · doc1.xml · nonDerivative · entry 3

GRAMMER ELIZABETH A · CIK 0001213041 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 71,312

F1 · shares: This transaction involved a gift of securities by the Reporting Person to her son, who shares Reporting Person's household. The Reporting Person disclaims beneficial ownership of the shares held by her son, and this report should not be deemed an admission that the Reporting Person is the beneficial owner of her son's shares for purposes of Section 16 or for any other purpose.

SEC source: 0001567619-21-000763 · doc1.xml · nonDerivative · entry 2

GRAMMER ELIZABETH A · CIK 0001213041 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 71,717

SEC source: 0001567619-21-000763 · doc1.xml · nonDerivative · entry 1

GRAMMER ELIZABETH A · CIK 0001213041 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 72,122

SEC source: 0001567619-20-021092 · doc1.xml · nonDerivative · entry 1

Bertrand William C JR · CIK 0001291937 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 74,658

F1 · shares: This transaction was executed in multiple trades in prices ranging from $7.08 to $7.10, inclusive. The price reported in Column 4 above reflects the weighted average purchase price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares purchased at each respective price within the range set forth in this footnote.

F1 · price: This transaction was executed in multiple trades in prices ranging from $7.08 to $7.10, inclusive. The price reported in Column 4 above reflects the weighted average purchase price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares purchased at each respective price within the range set forth in this footnote.

SEC source: 0001567619-20-021091 · doc1.xml · derivative · entry 7

GRAMMER ELIZABETH A · CIK 0001213041 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 78,000

Underlying: Common Stock · 41,000 shares

Expires 2029-01-17

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person on June 29, 2020.

F2 · derivative.exercise_date: The option becomes exercisable as it vests and the shares subject to the option vest in 48 successive, equal monthly installments on each monthly anniversary of January 17, 2019, subject to the Reporting Person's continued employment or service relationship with the Issuer on each such vesting date.

SEC source: 0001567619-20-021091 · doc1.xml · nonDerivative · entry 4

GRAMMER ELIZABETH A · CIK 0001213041 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 72,527

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person on June 29, 2020.

SEC source: 0001567619-20-021091 · doc1.xml · nonDerivative · entry 3

GRAMMER ELIZABETH A · CIK 0001213041 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 113,527

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person on June 29, 2020.

SEC source: 0001567619-20-021091 · doc1.xml · derivative · entry 6

GRAMMER ELIZABETH A · CIK 0001213041 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 119,000

Underlying: Common Stock · 1,000 shares

Expires 2029-01-17

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person on June 29, 2020.

F2 · derivative.exercise_date: The option becomes exercisable as it vests and the shares subject to the option vest in 48 successive, equal monthly installments on each monthly anniversary of January 17, 2019, subject to the Reporting Person's continued employment or service relationship with the Issuer on each such vesting date.

SEC source: 0001567619-20-021091 · doc1.xml · nonDerivative · entry 2

GRAMMER ELIZABETH A · CIK 0001213041 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 72,527

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person on June 29, 2020.

SEC source: 0001567619-20-021091 · doc1.xml · nonDerivative · entry 1

GRAMMER ELIZABETH A · CIK 0001213041 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 73,527

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person on June 29, 2020.

SEC source: 0001567619-20-020879 · doc1.xml · nonDerivative · entry 1

MOTT DAVID M · CIK 0001219871 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 417,284

F1 · price: This transaction was executed in multiple trades in prices ranging from $5.86 to $5.89, inclusive. The price reported in Column 4 above reflects the weighted average purchase price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares purchased at each respective price within the range set forth in this footnote.

F2 · balance_after: The Reporting Person holds 87,566 shares for the benefit of entities associated with New Enterprise Associates and disclaims beneficial ownership of such shares, except to the extent of his actual pecuniary interest therein.

SEC source: 0001567619-20-016851 · doc1.xml · nonDerivative · entry 1

Rodriguez Susan · CIK 0001812511 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,913

F1 · kind: Pursuant to an automatic sell-to-cover imposed by the terms of the initial grant of the restricted stock units ("RSUs") awards, the shares were sold upon the vesting of the RSUs solely to cover applicable withholding taxes.

F2 · price: This transaction was executed in multiple trades in prices ranging from $6.05 to $6.1611, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

SEC source: 0001567619-20-016845 · doc1.xml · nonDerivative · entry 2

Jacobs Jeffrey W · CIK 0001611193 · SVP, Technical Operations

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 96,811

F4 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 27, 2020.

SEC source: 0001567619-20-016849 · doc1.xml · nonDerivative · entry 1

Blanks Robert · CIK 0001815433 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 80,710

F1 · kind: Pursuant to an automatic sell-to-cover imposed by the terms of the initial grant of the restricted stock units ("RSUs") awards, the shares were sold upon the vesting of the RSUs solely to cover applicable withholding taxes.

F2 · price: The transaction was executed in multiple trades in prices ranging from $5.30 to $5.8517, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The reporting person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

SEC source: 0001567619-20-016848 · doc1.xml · nonDerivative · entry 1

Renz Justin A · CIK 0001466562 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,286

F1 · kind: Pursuant to an automatic sell-to-cover imposed by the terms of the initial grant of the restricted stock units ("RSUs") awards, the shares were sold upon the vesting of the RSUs solely to cover applicable withholding taxes.

F2 · price: This transaction was executed in multiple trades in prices ranging from $5.30 to $5.86, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

SEC source: 0001567619-20-016850 · doc1.xml · nonDerivative · entry 2

Rosenbaum David P. · CIK 0001611311 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · By Wife

Disclosed balance after: 21,662

F1 · kind: Pursuant to an automatic sell-to-cover imposed by the terms of the initial grant of the restricted stock units ("RSUs") awards, the shares were sold upon the vesting of the RSUs solely to cover applicable withholding taxes.

F4 · price: This transaction was executed in multiple trades in prices ranging from $5.30 to $5.84, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

F5 · balance_after: Reflects the adjusted total which includes the purchase of 2,183 shares on February 28, 2020 and 2,311 shares on August 31, 2020 under the Ardelyx Employee Stock Purchase Plan.

F6 · ownership.nature: The shares are directly held by the Reporting Person's wife.

SEC source: 0001567619-20-016850 · doc1.xml · nonDerivative · entry 1

Rosenbaum David P. · CIK 0001611311 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 133,047

F1 · kind: Pursuant to an automatic sell-to-cover imposed by the terms of the initial grant of the restricted stock units ("RSUs") awards, the shares were sold upon the vesting of the RSUs solely to cover applicable withholding taxes.

F2 · price: This transaction was executed in multiple trades in prices ranging from $5.30 to $5.86, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

F3 · balance_after: Reflects the adjusted total which includes the purchase of 2,062 shares on February 28, 2020 and 2,675 shares on August 31, 2020 under the Ardelyx Employee Stock Purchase Plan.

SEC source: 0001567619-20-016847 · doc1.xml · nonDerivative · entry 1

RAAB MICHAEL · CIK 0001321402 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 104,720

F1 · kind: Pursuant to an automatic sell-to-cover imposed by the terms of the initial grant of the restricted stock units ("RSUs") awards, the shares were sold upon the vesting of the RSUs solely to cover applicable withholding taxes.

F2 · price: The transaction was executed in multiple trades in prices ranging from $5.30 to $5.78, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The reporting person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

F3 · balance_after: Includes 3,000 shares acquired under the Issuer's Employee Stock Purchase Plan on August 31, 2020.

SEC source: 0001567619-20-016846 · doc1.xml · nonDerivative · entry 1

GRAMMER ELIZABETH A · CIK 0001213041 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 72,527

F1 · kind: Pursuant to an automatic sell-to-cover imposed by the terms of the initial grant of the restricted stock units ("RSUs") awards, the shares were sold upon the vesting of the RSUs solely to cover applicable withholding taxes.

F2 · price: This transaction was executed in multiple trades in prices ranging from $5.30 to $5.7797, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

F3 · balance_after: Includes 1,229 shares acquired under the Issuer's Employee Stock Purchase Plan on August 31, 2020.