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ALNY

ALNYLAM PHARMACEUTICALS, INC.

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3132
SEC CIK
0001178670
Parsed reports
483

Last 12 months

Inside the activity.

0 purchase rows · 279 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 2025031
Dec 202500
Jan 20260111
Feb 2026011
Mar 20260106
Apr 2026014
May 202600
Jun 202605
Jul 202600
Aug 202600
Sep 202600
Oct 202601

Latest available

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
November 22, 2017 Filed Nov 24, 2017 23:55 UTC
MARAGANORE JOHNDirector · Chief Executive Officer
SaleCommon Stock 25,263 $129.97 $3,283,432.11
Disclosure

SEC source: 0001553878-17-000069 · primary_doc.xml · nonDerivative · entry 2

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 197,862

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 13, 2017. The 73,415 options exercised and sold by the reporting person were due to expire on December 12, 2017.

F2 · price: Sale prices ranged from $129.39 to $130.35.

Read SEC document
November 22, 2017 Filed Nov 24, 2017 23:55 UTC
MARAGANORE JOHNDirector · Chief Executive Officer
Exercise / conversionCommon Stock 73,415 $31.39 $2,304,496.85
Disclosure

SEC source: 0001553878-17-000069 · primary_doc.xml · nonDerivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 223,125

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 13, 2017. The 73,415 options exercised and sold by the reporting person were due to expire on December 12, 2017.

Read SEC document
November 15, 2017 Filed Nov 17, 2017 22:35 UTC
MARAGANORE JOHNDirector · Chief Executive Officer
Exercise / conversionStock Option (Right to Buy) · Derivative 74,000 $0.00 Strike: $31.39 $0.00
Disclosure

SEC source: 0001553878-17-000068 · primary_doc.xml · derivative · entry 9

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 73,415

Underlying: Common Stock · 74,000 shares

Expires 2017-12-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 13, 2017. The 74,000 options exercised and sold by the reporting person were due to expire on December 12, 2017.

F9 · derivative.exercise_date: The stock option vested as to 25% of the shares on the first anniversary of the date of the stock option grant and as to an additional 6.25% of the shares each successive three month period thereafter.

F1 · derivative.expiration_date: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 13, 2017. The 74,000 options exercised and sold by the reporting person were due to expire on December 12, 2017.

Read SEC document
November 15, 2017 Filed Nov 17, 2017 22:35 UTC
MARAGANORE JOHNDirector · Chief Executive Officer
SaleCommon Stock 600 $130.22 $78,130.80
Disclosure

SEC source: 0001553878-17-000068 · primary_doc.xml · nonDerivative · entry 7

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 149,710

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 13, 2017. The 74,000 options exercised and sold by the reporting person were due to expire on December 12, 2017.

F7 · price: Sale prices ranged from $130.15 to $130.41.

Read SEC document
November 15, 2017 Filed Nov 17, 2017 22:35 UTC
MARAGANORE JOHNDirector · Chief Executive Officer
SaleCommon Stock 4,850 $129.57 $628,414.50
Disclosure

SEC source: 0001553878-17-000068 · primary_doc.xml · nonDerivative · entry 6

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 150,310

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 13, 2017. The 74,000 options exercised and sold by the reporting person were due to expire on December 12, 2017.

F6 · price: Sale prices ranged from $129.11 to $130.00.

Read SEC document
November 15, 2017 Filed Nov 17, 2017 22:35 UTC
MARAGANORE JOHNDirector · Chief Executive Officer
SaleCommon Stock 10,571 $128.48 $1,358,204.36
Disclosure

SEC source: 0001553878-17-000068 · primary_doc.xml · nonDerivative · entry 5

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 155,160

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 13, 2017. The 74,000 options exercised and sold by the reporting person were due to expire on December 12, 2017.

F5 · price: Sale prices ranged from $128.09 to $129.08.

Read SEC document
November 15, 2017 Filed Nov 17, 2017 22:35 UTC
MARAGANORE JOHNDirector · Chief Executive Officer
SaleCommon Stock 7,120 $127.54 $908,084.80
Disclosure

SEC source: 0001553878-17-000068 · primary_doc.xml · nonDerivative · entry 4

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 165,731

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 13, 2017. The 74,000 options exercised and sold by the reporting person were due to expire on December 12, 2017.

F4 · price: Sale prices ranged from $127.08 to $128.06.

Read SEC document
November 15, 2017 Filed Nov 17, 2017 22:35 UTC
MARAGANORE JOHNDirector · Chief Executive Officer
SaleCommon Stock 28,399 $126.60 $3,595,398.60
Disclosure

SEC source: 0001553878-17-000068 · primary_doc.xml · nonDerivative · entry 3

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 172,851

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 13, 2017. The 74,000 options exercised and sold by the reporting person were due to expire on December 12, 2017.

F3 · price: Sale prices ranged from $126.08 to $127.05.

Read SEC document
November 15, 2017 Filed Nov 17, 2017 22:35 UTC
MARAGANORE JOHNDirector · Chief Executive Officer
SaleCommon Stock 22,460 $125.54 $2,819,718.24
Disclosure

SEC source: 0001553878-17-000068 · primary_doc.xml · nonDerivative · entry 2

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 201,250

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 13, 2017. The 74,000 options exercised and sold by the reporting person were due to expire on December 12, 2017.

F2 · price: Sale prices ranged from $125.07 to $126.05.

Read SEC document
November 15, 2017 Filed Nov 17, 2017 22:35 UTC
MARAGANORE JOHNDirector · Chief Executive Officer
Exercise / conversionCommon Stock 74,000 $31.39 $2,322,860.00
Disclosure

SEC source: 0001553878-17-000068 · primary_doc.xml · nonDerivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 223,710

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 13, 2017. The 74,000 options exercised and sold by the reporting person were due to expire on December 12, 2017.

Read SEC document
November 06, 2017 Filed Nov 8, 2017 22:25 UTC
Mason MichaelVP, Finance and Treasurer
GrantPerformance Stock Option 2015 (right to buy) · Derivative 1,800 $0.00 Strike: $88.95 $0.00
Disclosure

SEC source: 0001553878-17-000066 · edgardoc.xml · derivative · entry 1

Mason Michael · CIK 0001514291 · VP, Finance and Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,800

Underlying: Common Stock · 1,800 shares

Expires 2025-12-18

F1 · kind: On December 18, 2015, the reporting person was granted a performance based stock option to purchase shares of ALNY common stock. One quarter of the shares subject to the option will vest upon the achievement of each of four specific clinical development and regulatory events, as approved by our compensation committee. Effective November 6, 2017, the compensation committee of the Company determined the first performance criterion had been met and the option vested as to one-quarter of the shares.

Read SEC document
November 06, 2017 Filed Nov 8, 2017 22:26 UTC GrantPerformance Stock Option 2015 (right to buy) · Derivative 7,500 $0.00 Strike: $88.95 $0.00
Disclosure

SEC source: 0001553878-17-000067 · edgardoc.xml · derivative · entry 1

Vaishnaw Akshay · CIK 0001458494 · EVP, R&D

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,500

Underlying: Common Stock · 7,500 shares

Expires 2025-12-18

F1 · kind: On December 18, 2015, the reporting person was granted a performance based stock option to purchase shares of ALNY common stock. One quarter of the shares subject to the option will vest upon the achievement of each of four specific clinical development and regulatory events, as approved by our compensation committee. Effective November 6, 2017, the compensation committee of the Company determined the first performance criterion had been met and the option vested as to one-quarter of the shares.

Read SEC document
November 06, 2017 Filed Nov 8, 2017 22:25 UTC
KEATING LAURIESVP, GC & Secretary
GrantPerformance Stock Option 2015 (right to buy) · Derivative 3,500 $0.00 Strike: $88.95 $0.00
Disclosure

SEC source: 0001553878-17-000064 · edgardoc.xml · derivative · entry 1

KEATING LAURIE · CIK 0001620743 · SVP, GC & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,500

Underlying: Common Stock · 3,500 shares

Expires 2025-12-18

F1 · kind: On December 18, 2015, the reporting person was granted a performance based stock option to purchase shares of ALNY common stock. One quarter of the shares subject to the option will vest upon the achievement of each of four specific clinical development and regulatory events, as approved by our compensation committee. Effective November 6, 2017, the compensation committee of the Company determined the first performance criterion had been met and the option vested as to one-quarter of the shares.

Read SEC document
November 06, 2017 Filed Nov 8, 2017 22:25 UTC
MARAGANORE JOHNDirector · Chief Executive Officer
GrantPerformance Stock Option 2015 (right to buy) · Derivative 16,250 $0.00 Strike: $88.95 $0.00
Disclosure

SEC source: 0001553878-17-000065 · edgardoc.xml · derivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,250

Underlying: Common Stock · 16,250 shares

Expires 2025-12-18

F1 · kind: On December 18, 2015, the reporting person was granted a performance based stock option to purchase shares of ALNY common stock. One quarter of the shares subject to the option will vest upon the achievement of each of four specific clinical development and regulatory events, as approved by our compensation committee. Effective November 6, 2017, the compensation committee of the Company determined the first performance criterion had been met and the option vested as to one-quarter of the shares.

Read SEC document
November 06, 2017 Filed Nov 8, 2017 22:25 UTC GrantPerformance Stock Option 2015 (right to buy) · Derivative 10,000 $0.00 Strike: $88.95 $0.00
Disclosure

SEC source: 0001553878-17-000063 · edgardoc.xml · derivative · entry 1

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Common Stock · 10,000 shares

Expires 2025-12-18

F1 · kind: On December 18, 2015, the reporting person was granted a performance based stock option to purchase shares of ALNY common stock. One quarter of the shares subject to the option will vest upon the achievement of each of four specific clinical development and regulatory events, as approved by our compensation committee. Effective November 6, 2017, the compensation committee of the Company determined the first performance criterion had been met and the option vested as to one-quarter of the shares.

Read SEC document
November 02, 2017 Filed Nov 4, 2017 00:14 UTC Exercise / conversionStock Option (right to buy) · Derivative 20,000 $0.00 Strike: $30.09 $0.00
Disclosure

SEC source: 0001553878-17-000057 · edgardoc.xml · derivative · entry 4

Ausiello Dennis A · CIK 0001381994 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 20,000 shares

Expires 2023-06-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on August 1, 2017.

F3 · derivative.exercise_date: The stock option will vest as to one third of the shares on each of the first, second and third anniversaries of the date of grant.

Read SEC document
November 02, 2017 Filed Nov 4, 2017 00:14 UTC SaleCommon Stock 20,000 $130.00 $2,600,000.00
Disclosure

SEC source: 0001553878-17-000057 · edgardoc.xml · nonDerivative · entry 2

Ausiello Dennis A · CIK 0001381994 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on August 1, 2017.

Read SEC document
November 02, 2017 Filed Nov 4, 2017 00:14 UTC Exercise / conversionCommon Stock 20,000 $30.09 $601,800.00
Disclosure

SEC source: 0001553878-17-000057 · edgardoc.xml · nonDerivative · entry 1

Ausiello Dennis A · CIK 0001381994 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on August 1, 2017.

Read SEC document
October 30, 2017 Filed Nov 1, 2017 21:33 UTC Exercise / conversionStock Option (Right to Buy) · Derivative 33,666 $0.00 Strike: $21.35 $0.00
Disclosure

SEC source: 0001553878-17-000055 · primary_doc.xml · derivative · entry 7

Vaishnaw Akshay · CIK 0001458494 · EVP, R&D

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 33,666 shares

Expires 2018-12-08

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on August 29, 2017.

F7 · derivative.exercise_date: The stock option vested as to 25% of the shares on the first anniversary of the date of the stock option grant and as to an additional 6.25% of the shares each successive three month period thereafter.

Read SEC document
October 30, 2017 Filed Nov 1, 2017 21:33 UTC SaleCommon Stock 3,693 $122.79 $453,463.47
Disclosure

SEC source: 0001553878-17-000055 · primary_doc.xml · nonDerivative · entry 5

Vaishnaw Akshay · CIK 0001458494 · EVP, R&D

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,535

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on August 29, 2017.

F5 · price: Sale prices ranged from $122.45 to $123.01.

Read SEC document
October 30, 2017 Filed Nov 1, 2017 21:33 UTC SaleCommon Stock 17,755 $121.69 $2,160,605.95
Disclosure

SEC source: 0001553878-17-000055 · primary_doc.xml · nonDerivative · entry 4

Vaishnaw Akshay · CIK 0001458494 · EVP, R&D

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,228

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on August 29, 2017.

F4 · price: Sale prices ranged from $121.26 to $122.19.

Read SEC document
October 30, 2017 Filed Nov 1, 2017 21:33 UTC SaleCommon Stock 11,418 $120.78 $1,379,066.04
Disclosure

SEC source: 0001553878-17-000055 · primary_doc.xml · nonDerivative · entry 3

Vaishnaw Akshay · CIK 0001458494 · EVP, R&D

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,983

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on August 29, 2017.

F3 · price: Sale prices ranged from $120.32 to $121.25.

Read SEC document
October 30, 2017 Filed Nov 1, 2017 21:33 UTC SaleCommon Stock 800 $119.79 $95,832.00
Disclosure

SEC source: 0001553878-17-000055 · primary_doc.xml · nonDerivative · entry 2

Vaishnaw Akshay · CIK 0001458494 · EVP, R&D

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 44,401

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on August 29, 2017.

F2 · price: Sale prices ranged from $119.30 to $120.28.

Read SEC document
October 30, 2017 Filed Nov 1, 2017 21:33 UTC Exercise / conversionCommon Stock 33,666 $21.35 $718,769.10
Disclosure

SEC source: 0001553878-17-000055 · primary_doc.xml · nonDerivative · entry 1

Vaishnaw Akshay · CIK 0001458494 · EVP, R&D

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,201

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on August 29, 2017.

Read SEC document
October 16, 2017 Filed Aug 14, 2018 21:54 UTC
Soni Manmeet SinghChief Financial Officer
OtherCommon Stock 11 $0.00 $0.00
Disclosure

SEC source: 0001735276-18-000048 · edgardoc.xml · nonDerivative · entry 2

Soni Manmeet Singh · CIK 0001569769 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · by Managed Account

Disclosed balance after: 13

F1 · kind: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

F1 · price: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

F1 · ownership.nature: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

Read SEC document
October 02, 2017 Filed Oct 4, 2017 23:45 UTC Exercise / conversionStock Option (Right to Buy) · Derivative 85,316 $0.00 Strike: $21.35 $0.00
Disclosure

SEC source: 0001553878-17-000054 · primary_doc.xml · derivative · entry 4

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 85,316 shares

Expires 2018-12-08

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sale reported on this Form 4 was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 23, 2017.

F3 · derivative.exercise_date: The stock option vested as to 25% of the shares on the first anniversary of the grant date and as to an additional 6.25% of the shares each successive three month period thereafter.

Read SEC document
October 02, 2017 Filed Oct 4, 2017 23:45 UTC SaleCommon Stock 85,316 $125.00 $10,664,500.00
Disclosure

SEC source: 0001553878-17-000054 · primary_doc.xml · nonDerivative · entry 2

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 100,428

F1 · kind: The sale reported on this Form 4 was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 23, 2017.

Read SEC document
October 02, 2017 Filed Oct 4, 2017 23:45 UTC Exercise / conversionCommon Stock 85,316 $21.35 $1,821,496.60
Disclosure

SEC source: 0001553878-17-000054 · primary_doc.xml · nonDerivative · entry 1

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 185,744

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sale reported on this Form 4 was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 23, 2017.

Read SEC document
September 22, 2017 Filed Feb 9, 2018 22:04 UTC
Mason MichaelVP, Finance and Treasurer
OtherCommon Stock 1,950 $115.47 $225,166.50
Disclosure

SEC source: 0001553878-18-000001 · primary_doc.xml · nonDerivative · entry 1

Mason Michael · CIK 0001514291 · VP, Finance and Treasurer

10b5-1 filing: Not disclosed

Ownership: Indirect · By Managed Account

Disclosed balance after: 226

F1 · ownership.nature: The reporting person has diversified his retirement plan by selling shares of ALNY common stock in his 401(k) plan received from the ALNY 401(k) matching contribution program.

Read SEC document
September 21, 2017 Filed Sep 22, 2017 21:05 UTC Exercise / conversionStock Option (Right to Buy) · Derivative 5,359 $0.00 Strike: $18.66 $0.00
Disclosure

SEC source: 0001553878-17-000047 · primary_doc.xml · derivative · entry 8

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 94,641

Underlying: Common Stock · 5,359 shares

Expires 2022-12-20

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: The stock option vests as to 25% of the shares on the first anniversary of the date of the stock option grant and as to an additional 6.25% of the shares each successive three month period thereafter.

Read SEC document
September 21, 2017 Filed Sep 22, 2017 21:05 UTC Exercise / conversionStock Option (Right to Buy) · Derivative 6,485 $0.00 Strike: $7.10 $0.00
Disclosure

SEC source: 0001553878-17-000047 · primary_doc.xml · derivative · entry 7

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 85,915

Underlying: Common Stock · 6,485 shares

Expires 2021-11-30

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: The stock option vests as to 25% of the shares on the first anniversary of the date of the stock option grant and as to an additional 6.25% of the shares each successive three month period thereafter.

Read SEC document
September 21, 2017 Filed Sep 22, 2017 21:05 UTC Exercise / conversionCommon Stock 5,359 $18.66 $99,998.94
Disclosure

SEC source: 0001553878-17-000047 · primary_doc.xml · nonDerivative · entry 4

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 100,428

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
September 21, 2017 Filed Sep 22, 2017 21:05 UTC Exercise / conversionCommon Stock 6,485 $7.10 $46,043.50
Disclosure

SEC source: 0001553878-17-000047 · primary_doc.xml · nonDerivative · entry 3

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 95,069

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
September 20, 2017 Filed Sep 22, 2017 21:11 UTC GrantPerformance Stock Option 2013 (right to buy) · Derivative 10,834 $0.00 Strike: $63.00 $0.00
Disclosure

SEC source: 0001553878-17-000053 · edgardoc.xml · derivative · entry 1

Vaishnaw Akshay · CIK 0001458494 · EVP, R&D

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,834

Underlying: Common Stock · 10,834 shares

Expires 2023-12-17

F1 · kind: On December 18, 2013, the reporting person was granted a performance based stock option to purchase shares of ALNY Common Stock. One-third of the shares subject to the option will vest upon the achievement of each of three specific clinical development and regulatory events, as approved by our compensation committee. Effective September 20, 2017, the compensation committee of the company determined the second performance criteria had been met and the option will vest as to one-third of the shares.

Read SEC document
September 20, 2017 Filed Sep 22, 2017 21:09 UTC
Mason MichaelVP, Finance and Treasurer
GrantPerformance Stock Option 2013 (right to buy) · Derivative 1,667 $0.00 Strike: $63.00 $0.00
Disclosure

SEC source: 0001553878-17-000052 · edgardoc.xml · derivative · entry 1

Mason Michael · CIK 0001514291 · VP, Finance and Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,667

Underlying: Common Stock · 1,667 shares

Expires 2023-12-17

F1 · kind: On December 18, 2013, the reporting person was granted a performance based stock option to purchase shares of ALNY Common Stock. One-third of the shares subject to the option will vest upon the achievement of each of three specific clinical development and regulatory events, as approved by our compensation committee. Effective September 20, 2017, the compensation committee of the company determined the second performance criteria had been met and the option will vest as to one-third of the shares.

Read SEC document
September 20, 2017 Filed Sep 22, 2017 21:08 UTC
MARAGANORE JOHNDirector · Chief Executive Officer
GrantPerformance Stock Option 2013 (right to buy) · Derivative 25,000 $0.00 Strike: $63.00 $0.00
Disclosure

SEC source: 0001553878-17-000051 · edgardoc.xml · derivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,000

Underlying: Common Stock · 25,000 shares

Expires 2023-12-17

F1 · kind: On December 18, 2013, the reporting person was granted a performance based stock option to purchase shares of ALNY Common Stock. One-third of the shares subject to the option will vest upon the achievement of each of three specific clinical development and regulatory events, as approved by our compensation committee. Effective September 20, 2017, the compensation committee of the company determined the second performance criteria had been met and the option will vest as to one-third of the shares.

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September 20, 2017 Filed Sep 22, 2017 21:05 UTC Exercise / conversionStock Option (Right to Buy) · Derivative 76,815 $0.00 Strike: $31.39 $0.00
Disclosure

SEC source: 0001553878-17-000047 · primary_doc.xml · derivative · entry 9

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 76,815 shares

Expires 2017-12-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 23, 2017. The 76,815 options exercised and sold by the reporting person were due to expire on December 12, 2017.

F4 · derivative.exercise_date: The stock option vests as to 25% of the shares on the first anniversary of the date of the stock option grant and as to an additional 6.25% of the shares each successive three month period thereafter.

F1 · derivative.expiration_date: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 23, 2017. The 76,815 options exercised and sold by the reporting person were due to expire on December 12, 2017.

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September 20, 2017 Filed Sep 22, 2017 21:05 UTC GrantPerformance Stock Option 2013 (Right to Buy) · Derivative 15,000 $0.00 Strike: $63.00 $0.00
Disclosure

SEC source: 0001553878-17-000047 · primary_doc.xml · derivative · entry 6

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 15,000 shares

Expires 2023-12-17

F3 · kind: On December 18, 2013, the reporting person was granted a performance based stock option to purchase shares of ALNY Common Stock. One-third of the shares subject to the option will vest upon the achievement of each of three specific clinical development and regulatory events, as approved by the compensation committee of the Company. Effective September 20, 2017, the compensation committee of the Company determined the second performance criteria had been met and the option was vested as to one-third of the shares.

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September 20, 2017 Filed Sep 22, 2017 21:05 UTC SaleCommon Stock 76,815 $100.00 $7,681,500.00
Disclosure

SEC source: 0001553878-17-000047 · primary_doc.xml · nonDerivative · entry 2

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 88,584

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 23, 2017. The 76,815 options exercised and sold by the reporting person were due to expire on December 12, 2017.

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September 20, 2017 Filed Sep 22, 2017 21:05 UTC Exercise / conversionCommon Stock 76,815 $31.39 $2,411,222.85
Disclosure

SEC source: 0001553878-17-000047 · primary_doc.xml · nonDerivative · entry 1

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 165,399

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 23, 2017. The 76,815 options exercised and sold by the reporting person were due to expire on December 12, 2017.

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July 25, 2017 Filed Aug 14, 2018 21:54 UTC
Soni Manmeet SinghChief Financial Officer
OtherCommon Stock 2 $0.00 $0.00
Disclosure

SEC source: 0001735276-18-000048 · edgardoc.xml · nonDerivative · entry 1

Soni Manmeet Singh · CIK 0001569769 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · by Managed Account

Disclosed balance after: 2

F1 · kind: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

F1 · price: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

F1 · ownership.nature: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

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July 07, 2017 Filed Jul 11, 2017 20:35 UTC GrantPerformance Stock Option 2014 (right to buy) · Derivative 11,709 $0.00 Strike: $96.45 $0.00
Disclosure

SEC source: 0001553878-17-000046 · edgardoc.xml · derivative · entry 1

Vaishnaw Akshay · CIK 0001458494 · EVP, R&D

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,418

Underlying: Common Stock · 11,709 shares

Expires 2024-12-17

F1 · kind: On December 17, 2014, the reporting person was granted a performance based stock option to purchase shares of ALNY Common Stock. One-third of the shares subject to the option will vest upon the achievement of each of three specific clinical development and regulatory events, as approved by our compensation committee. Effective July 7, 2017, the compensation committee of the Company determined the second performance criteria had been met and the option vested as to one-third of the shares.

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July 07, 2017 Filed Jul 11, 2017 20:35 UTC
Mason MichaelVP, Finance and Treasurer
GrantPerformance Stock Option 2014 (right to buy) · Derivative 2,750 $0.00 Strike: $96.45 $0.00
Disclosure

SEC source: 0001553878-17-000045 · edgardoc.xml · derivative · entry 1

Mason Michael · CIK 0001514291 · VP, Finance and Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,500

Underlying: Common Stock · 2,750 shares

Expires 2024-12-17

F1 · kind: On December 17, 2014, the reporting person was granted a performance based stock option to purchase shares of ALNY Common Stock. One-third of the shares subject to the option will vest upon the achievement of each of three specific clinical development and regulatory events, as approved by our compensation committee. Effective July 7, 2017, the compensation committee of the Company determined the second performance criteria had been met and the option vested as to one-third of the shares.

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July 07, 2017 Filed Jul 11, 2017 20:34 UTC
MARAGANORE JOHNDirector · Chief Executive Officer
GrantPerformance Stock Option 2014 (right to buy) · Derivative 25,000 $0.00 Strike: $96.45 $0.00
Disclosure

SEC source: 0001553878-17-000044 · edgardoc.xml · derivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 50,000

Underlying: Common Stock · 25,000 shares

Expires 2024-12-17

F1 · kind: On December 17, 2014, the reporting person was granted a performance based stock option to purchase shares of ALNY Common Stock. One-third of the shares subject to the option will vest upon the achievement of each of three specific clinical development and regulatory events, as approved by our compensation committee. Effective July 7, 2017, the compensation committee of the Company determined the second performance criteria had been met and the option vested as to one-third of the shares.

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July 07, 2017 Filed Jul 11, 2017 20:34 UTC
KEATING LAURIESVP, GC & Secretary
GrantPerformance Stock Option 2014 (right to buy) · Derivative 1,987 $0.00 Strike: $96.45 $0.00
Disclosure

SEC source: 0001553878-17-000043 · edgardoc.xml · derivative · entry 1

KEATING LAURIE · CIK 0001620743 · SVP, GC & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,974

Underlying: Common Stock · 1,987 shares

Expires 2024-12-17

F1 · kind: On December 17, 2014, the reporting person was granted a performance based stock option to purchase shares of ALNY Common Stock. One-third of the shares subject to the option will vest upon the achievement of each of three specific clinical development and regulatory events, as approved by our compensation committee. Effective July 7, 2017, the compensation committee of the Company determined the second performance criteria had been met and the option vested as to one-third of the shares.

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July 07, 2017 Filed Jul 11, 2017 20:34 UTC GrantPerformance Stock Option 2014 (right to buy) · Derivative 15,875 $0.00 Strike: $96.45 $0.00
Disclosure

SEC source: 0001553878-17-000042 · edgardoc.xml · derivative · entry 1

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,750

Underlying: Common Stock · 15,875 shares

Expires 2024-12-17

F1 · kind: On December 17, 2014, the reporting person was granted a performance based stock option to purchase shares of ALNY Common Stock. One-third of the shares subject to the option will vest upon the achievement of each of three specific clinical development and regulatory events, as approved by our compensation committee. Effective July 7, 2017, the compensation committee of the Company determined the second performance criteria had been met and the option vested as to one-third of the shares.

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June 13, 2017 Filed Jun 15, 2017 21:45 UTC Exercise / conversionStock Option (Right to Buy) · Derivative 328 $0.00 Strike: $21.35 $0.00
Disclosure

SEC source: 0001553878-17-000036 · primary_doc.xml · derivative · entry 6

Vaishnaw Akshay · CIK 0001458494 · EVP, R&D

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,666

Underlying: Common Stock · 328 shares

Expires 2018-12-08

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The stock option vests as to 25% of the shares on the first anniversary of the date of the stock option grant and as to an additional 6.25% of the shares each successive three month period thereafter.

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June 13, 2017 Filed Jun 15, 2017 21:45 UTC Exercise / conversionStock Option (Right to Buy) · Derivative 1,340 $0.00 Strike: $18.66 $0.00
Disclosure

SEC source: 0001553878-17-000036 · primary_doc.xml · derivative · entry 5

Vaishnaw Akshay · CIK 0001458494 · EVP, R&D

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 44,641

Underlying: Common Stock · 1,340 shares

Expires 2022-12-20

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The stock option vests as to 25% of the shares on the first anniversary of the date of the stock option grant and as to an additional 6.25% of the shares each successive three month period thereafter.

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June 13, 2017 Filed Jun 15, 2017 21:45 UTC Tax withholdingCommon Stock 430 $74.31 $31,953.30
Disclosure

SEC source: 0001553878-17-000036 · primary_doc.xml · nonDerivative · entry 3

Vaishnaw Akshay · CIK 0001458494 · EVP, R&D

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,535

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June 13, 2017 Filed Jun 15, 2017 21:45 UTC Exercise / conversionCommon Stock 1,340 $18.66 $25,004.40
Disclosure

SEC source: 0001553878-17-000036 · primary_doc.xml · nonDerivative · entry 2

Vaishnaw Akshay · CIK 0001458494 · EVP, R&D

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,965

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.