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Nasdaq · USD

ALNY

ALNYLAM PHARMACEUTICALS, INC.

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Tapewire entity
3132
SEC CIK
0001178670
Parsed reports
483

Last 12 months

Inside the activity.

0 purchase rows · 279 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 2025031
Dec 202500
Jan 20260111
Feb 2026011
Mar 20260106
Apr 2026014
May 202600
Jun 202605
Jul 202600
Aug 202600
Sep 202600
Oct 202601

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
January 04, 2018 Filed Jan 8, 2018 22:02 UTC
Mason MichaelVP, Finance and Treasurer
Exercise / conversionStock Option (right to buy) · Derivative 3,600 $0.00 Strike: $88.95 $0.00
Disclosure

SEC source: 0001325812-18-000004 · edgardoc.xml · derivative · entry 21

Mason Michael · CIK 0001514291 · VP, Finance and Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,600

Underlying: Common Stock · 3,600 shares

Expires 2025-12-18

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on October 2, 2017.

F9 · derivative.exercise_date: The stock option vests as to 25% of the shares on the 1st anniversary of the date of the stock option grant and as to an additional 6.25% of the shares each successive three month period thereafter.

Read SEC document
January 04, 2018 Filed Jan 8, 2018 22:02 UTC
Mason MichaelVP, Finance and Treasurer
Exercise / conversionStock Option (right to buy) · Derivative 3,439 $0.00 Strike: $63.00 $0.00
Disclosure

SEC source: 0001325812-18-000004 · edgardoc.xml · derivative · entry 20

Mason Michael · CIK 0001514291 · VP, Finance and Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 3,439 shares

Expires 2023-12-18

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on October 2, 2017.

F9 · derivative.exercise_date: The stock option vests as to 25% of the shares on the 1st anniversary of the date of the stock option grant and as to an additional 6.25% of the shares each successive three month period thereafter.

Read SEC document
January 04, 2018 Filed Jan 8, 2018 22:02 UTC
Mason MichaelVP, Finance and Treasurer
Exercise / conversionStock Option (right to buy) · Derivative 1,388 $0.00 Strike: $42.22 $0.00
Disclosure

SEC source: 0001325812-18-000004 · edgardoc.xml · derivative · entry 19

Mason Michael · CIK 0001514291 · VP, Finance and Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,162

Underlying: Common Stock · 1,388 shares

Expires 2026-12-20

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on October 2, 2017.

F9 · derivative.exercise_date: The stock option vests as to 25% of the shares on the 1st anniversary of the date of the stock option grant and as to an additional 6.25% of the shares each successive three month period thereafter.

Read SEC document
January 04, 2018 Filed Jan 8, 2018 22:02 UTC
Mason MichaelVP, Finance and Treasurer
Exercise / conversionPerformance Stock Option 2014 (right to buy) · Derivative 2,750 $0.00 Strike: $96.45 $0.00
Disclosure

SEC source: 0001325812-18-000004 · edgardoc.xml · derivative · entry 18

Mason Michael · CIK 0001514291 · VP, Finance and Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 2,750 shares

Expires 2024-12-17

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on October 2, 2017.

Read SEC document
January 04, 2018 Filed Jan 8, 2018 22:02 UTC
Mason MichaelVP, Finance and Treasurer
Exercise / conversionPerformance Stock Option 2014 (right to buy) · Derivative 2,750 $0.00 Strike: $96.45 $0.00
Disclosure

SEC source: 0001325812-18-000004 · edgardoc.xml · derivative · entry 17

Mason Michael · CIK 0001514291 · VP, Finance and Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,750

Underlying: Common Stock · 2,750 shares

Expires 2024-12-17

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on October 2, 2017.

Read SEC document
January 04, 2018 Filed Jan 8, 2018 22:02 UTC
Mason MichaelVP, Finance and Treasurer
Exercise / conversionPerformance Stock Option 2013 (right to buy) · Derivative 1,667 $0.00 Strike: $63.00 $0.00
Disclosure

SEC source: 0001325812-18-000004 · edgardoc.xml · derivative · entry 16

Mason Michael · CIK 0001514291 · VP, Finance and Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 1,667 shares

Expires 2023-12-17

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on October 2, 2017.

Read SEC document
January 04, 2018 Filed Jan 8, 2018 22:02 UTC
Mason MichaelVP, Finance and Treasurer
SaleCommon Stock 600 $135.00 $81,000.00
Disclosure

SEC source: 0001325812-18-000004 · edgardoc.xml · nonDerivative · entry 14

Mason Michael · CIK 0001514291 · VP, Finance and Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on October 2, 2017.

F7 · price: Sale prices ranged from $134.94 to $135.10

Read SEC document
January 04, 2018 Filed Jan 8, 2018 22:02 UTC
Mason MichaelVP, Finance and Treasurer
SaleCommon Stock 400 $133.83 $53,532.00
Disclosure

SEC source: 0001325812-18-000004 · edgardoc.xml · nonDerivative · entry 13

Mason Michael · CIK 0001514291 · VP, Finance and Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 600

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on October 2, 2017.

F6 · price: Sale prices ranged from $133.78 to $134.11.

Read SEC document
January 04, 2018 Filed Jan 8, 2018 22:02 UTC
Mason MichaelVP, Finance and Treasurer
SaleCommon Stock 1,591 $132.98 $211,571.18
Disclosure

SEC source: 0001325812-18-000004 · edgardoc.xml · nonDerivative · entry 12

Mason Michael · CIK 0001514291 · VP, Finance and Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,000

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on October 2, 2017.

F5 · price: Sale prices ranged from $132.75 to $133.71.

Read SEC document
January 04, 2018 Filed Jan 8, 2018 22:02 UTC
Mason MichaelVP, Finance and Treasurer
SaleCommon Stock 12,405 $132.18 $1,639,692.90
Disclosure

SEC source: 0001325812-18-000004 · edgardoc.xml · nonDerivative · entry 11

Mason Michael · CIK 0001514291 · VP, Finance and Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,591

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on October 2, 2017.

F4 · price: Sale prices ranged from $131.75 to $132.71.

Read SEC document
January 04, 2018 Filed Jan 8, 2018 22:02 UTC
Mason MichaelVP, Finance and Treasurer
SaleCommon Stock 16,500 $131.20 $2,164,800.00
Disclosure

SEC source: 0001325812-18-000004 · edgardoc.xml · nonDerivative · entry 10

Mason Michael · CIK 0001514291 · VP, Finance and Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,996

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on October 2, 2017.

F3 · price: Sale prices ranged from $130.74 to $131.73.

Read SEC document
January 04, 2018 Filed Jan 8, 2018 22:02 UTC
Mason MichaelVP, Finance and Treasurer
SaleCommon Stock 5,249 $130.42 $684,574.58
Disclosure

SEC source: 0001325812-18-000004 · edgardoc.xml · nonDerivative · entry 9

Mason Michael · CIK 0001514291 · VP, Finance and Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,496

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on October 2, 2017.

F2 · price: Sale prices ranged from $129.74 to $130.72.

Read SEC document
January 04, 2018 Filed Jan 8, 2018 22:02 UTC
Mason MichaelVP, Finance and Treasurer
Exercise / conversionCommon Stock 3,439 $63.00 $216,657.00
Disclosure

SEC source: 0001325812-18-000004 · edgardoc.xml · nonDerivative · entry 8

Mason Michael · CIK 0001514291 · VP, Finance and Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,745

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on October 2, 2017.

Read SEC document
January 04, 2018 Filed Jan 8, 2018 22:02 UTC
Mason MichaelVP, Finance and Treasurer
Exercise / conversionCommon Stock 6,187 $96.45 $596,736.15
Disclosure

SEC source: 0001325812-18-000004 · edgardoc.xml · nonDerivative · entry 7

Mason Michael · CIK 0001514291 · VP, Finance and Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,306

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on October 2, 2017.

Read SEC document
January 04, 2018 Filed Jan 8, 2018 22:02 UTC
Mason MichaelVP, Finance and Treasurer
Exercise / conversionCommon Stock 10,000 $97.72 $977,200.00
Disclosure

SEC source: 0001325812-18-000004 · edgardoc.xml · nonDerivative · entry 6

Mason Michael · CIK 0001514291 · VP, Finance and Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,119

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on October 2, 2017.

Read SEC document
January 04, 2018 Filed Jan 8, 2018 22:02 UTC
Mason MichaelVP, Finance and Treasurer
Exercise / conversionCommon Stock 2,750 $96.45 $265,237.50
Disclosure

SEC source: 0001325812-18-000004 · edgardoc.xml · nonDerivative · entry 5

Mason Michael · CIK 0001514291 · VP, Finance and Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,119

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on October 2, 2017.

Read SEC document
January 04, 2018 Filed Jan 8, 2018 22:02 UTC
Mason MichaelVP, Finance and Treasurer
Exercise / conversionCommon Stock 2,750 $96.45 $265,237.50
Disclosure

SEC source: 0001325812-18-000004 · edgardoc.xml · nonDerivative · entry 4

Mason Michael · CIK 0001514291 · VP, Finance and Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,369

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on October 2, 2017.

Read SEC document
January 04, 2018 Filed Jan 8, 2018 22:02 UTC
Mason MichaelVP, Finance and Treasurer
Exercise / conversionCommon Stock 3,600 $88.95 $320,220.00
Disclosure

SEC source: 0001325812-18-000004 · edgardoc.xml · nonDerivative · entry 3

Mason Michael · CIK 0001514291 · VP, Finance and Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,619

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on October 2, 2017.

Read SEC document
January 04, 2018 Filed Jan 8, 2018 22:02 UTC
Mason MichaelVP, Finance and Treasurer
Exercise / conversionCommon Stock 1,667 $63.00 $105,021.00
Disclosure

SEC source: 0001325812-18-000004 · edgardoc.xml · nonDerivative · entry 2

Mason Michael · CIK 0001514291 · VP, Finance and Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,019

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on October 2, 2017.

Read SEC document
January 04, 2018 Filed Jan 8, 2018 22:02 UTC
Mason MichaelVP, Finance and Treasurer
Exercise / conversionCommon Stock 1,388 $42.22 $58,601.36
Disclosure

SEC source: 0001325812-18-000004 · edgardoc.xml · nonDerivative · entry 1

Mason Michael · CIK 0001514291 · VP, Finance and Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,352

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on October 2, 2017.

Read SEC document
December 30, 2017 Filed Jan 3, 2018 22:26 UTC
Mason MichaelVP, Finance and Treasurer
Exercise / conversionRestricted Stock Unit · Derivative 8,502 $0.00 $0.00
Disclosure

SEC source: 0001325812-18-000002 · primary_doc.xml · derivative · entry 4

Mason Michael · CIK 0001514291 · VP, Finance and Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 8,502 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of ALNY common stock.

F3 · derivative.exercise_date: The restricted stock units vest in full on December 30, 2017.

F3 · derivative.expiration_date: The restricted stock units vest in full on December 30, 2017.

Read SEC document
December 30, 2017 Filed Jan 3, 2018 22:26 UTC
Mason MichaelVP, Finance and Treasurer
Tax withholdingCommon Stock 3,538 $127.05 $449,502.90
Disclosure

SEC source: 0001325812-18-000002 · primary_doc.xml · nonDerivative · entry 2

Mason Michael · CIK 0001514291 · VP, Finance and Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,964

Read SEC document
December 30, 2017 Filed Jan 3, 2018 22:26 UTC
Mason MichaelVP, Finance and Treasurer
Exercise / conversionCommon Stock 8,502 $0.00 $0.00
Disclosure

SEC source: 0001325812-18-000002 · primary_doc.xml · nonDerivative · entry 1

Mason Michael · CIK 0001514291 · VP, Finance and Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,502

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
December 29, 2017 Filed Jan 3, 2018 22:13 UTC
KEATING LAURIESVP, GC & Secretary
Exercise / conversionStock Option (right to buy) · Derivative 3,000 $0.00 Strike: $77.40 $0.00
Disclosure

SEC source: 0001325812-18-000001 · primary_doc.xml · derivative · entry 3

KEATING LAURIE · CIK 0001620743 · SVP, GC & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 92,000

Underlying: Common Stock · 3,000 shares

Expires 2024-09-22

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The stock option vests as to 25% of the shares on the 1st anniversary of the date of the stock option grant and as to an additional 6.25% of the shares each successive three month period thereafter.

Read SEC document
December 29, 2017 Filed Jan 3, 2018 22:13 UTC
KEATING LAURIESVP, GC & Secretary
Exercise / conversionCommon Stock 3,000 $77.40 $232,200.00
Disclosure

SEC source: 0001325812-18-000001 · primary_doc.xml · nonDerivative · entry 1

KEATING LAURIE · CIK 0001620743 · SVP, GC & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,500

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
December 20, 2017 Filed Dec 21, 2017 22:00 UTC
Mason MichaelVP, Finance and Treasurer
GrantPerformance Stock Option 2016 (right to buy) · Derivative 1,388 $0.00 Strike: $42.22 $0.00
Disclosure

SEC source: 0001325812-17-000040 · edgardoc.xml · derivative · entry 1

Mason Michael · CIK 0001514291 · VP, Finance and Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,388

Underlying: Common Stock · 1,388 shares

Expires 2026-12-20

F1 · kind: On December 20, 2016, the reporting person was granted a performance based stock option to purchase shares of ALNY common stock. One quarter of the shares subject to the option will vest upon the achievement of each of four specific clinical development, regulatory or commercial events, as approved by our compensation committee. Effective December 20, 2017, the compensation committee of the Company determined the first performance criterion had been met and the option vested as to one-quarter of the shares.

Read SEC document
December 20, 2017 Filed Dec 21, 2017 22:00 UTC
Greenstreet YvonneEVP, Chief Operating Officer
GrantPerformance Stock Option 2016 (right to buy) · Derivative 6,250 $0.00 Strike: $42.22 $0.00
Disclosure

SEC source: 0001325812-17-000039 · edgardoc.xml · derivative · entry 1

Greenstreet Yvonne · CIK 0001446125 · EVP, Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,250

Underlying: Common Stock · 6,250 shares

Expires 2026-12-20

F1 · kind: On December 20, 2016, the reporting person was granted a performance based stock option to purchase shares of ALNY common stock. One quarter of the shares subject to the option will vest upon the achievement of each of four specific clinical development, regulatory or commercial events, as approved by our compensation committee. Effective December 20, 2017, the compensation committee of the Company determined the first performance criterion had been met and the option vested as to one-quarter of the shares.

Read SEC document
December 20, 2017 Filed Dec 21, 2017 22:00 UTC
KEATING LAURIESVP, GC & Secretary
Exercise / conversionStock Option (right to buy) · Derivative 6,249 $0.00 Strike: $42.22 $0.00
Disclosure

SEC source: 0001325812-17-000038 · primary_doc.xml · derivative · entry 7

KEATING LAURIE · CIK 0001620743 · SVP, GC & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,751

Underlying: Common Stock · 6,249 shares

Expires 2026-12-20

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 22, 2017.

F7 · derivative.exercise_date: The stock option vests as to 25% of the shares on the 1st anniversary of the date of the stock option grant and as to an additional 6.25% of the shares each successive three month period thereafter.

Read SEC document
December 20, 2017 Filed Dec 21, 2017 22:00 UTC
KEATING LAURIESVP, GC & Secretary
GrantPerformance Based Stock Option 2016 (right to buy) · Derivative 6,250 $0.00 Strike: $42.22 $0.00
Disclosure

SEC source: 0001325812-17-000038 · primary_doc.xml · derivative · entry 6

KEATING LAURIE · CIK 0001620743 · SVP, GC & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,250

Underlying: Common Stock · 6,250 shares

Expires 2026-12-20

F6 · kind: On December 20, 2016, the reporting person was granted a performance based stock option to purchase shares of ALNY common stock. One quarter of the shares subject to the option will vest upon the achievement of each of four specific clinical development, regulatory or commercial events, as approved by our compensation committee. Effective December 20, 2017, the compensation committee of the Company determined the first performance criterion had been met and the option vested as to one-quarter of the shares.

Read SEC document
December 20, 2017 Filed Dec 21, 2017 22:00 UTC
KEATING LAURIESVP, GC & Secretary
SaleCommon Stock 300 $122.53 $36,759.99
Disclosure

SEC source: 0001325812-17-000038 · primary_doc.xml · nonDerivative · entry 4

KEATING LAURIE · CIK 0001620743 · SVP, GC & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,500

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 22, 2017.

F4 · price: Sale prices ranged from $122.51 to $122.58.

Read SEC document
December 20, 2017 Filed Dec 21, 2017 22:00 UTC
KEATING LAURIESVP, GC & Secretary
SaleCommon Stock 1,900 $121.67 $231,181.93
Disclosure

SEC source: 0001325812-17-000038 · primary_doc.xml · nonDerivative · entry 3

KEATING LAURIE · CIK 0001620743 · SVP, GC & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,800

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 22, 2017.

F3 · price: Sale prices ranged from $121.49 to $122.39.

Read SEC document
December 20, 2017 Filed Dec 21, 2017 22:00 UTC
KEATING LAURIESVP, GC & Secretary
SaleCommon Stock 4,049 $120.88 $489,456.48
Disclosure

SEC source: 0001325812-17-000038 · primary_doc.xml · nonDerivative · entry 2

KEATING LAURIE · CIK 0001620743 · SVP, GC & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,700

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 22, 2017.

F2 · price: Sale prices ranged from $120.45 to $121.40.

Read SEC document
December 20, 2017 Filed Dec 21, 2017 22:00 UTC
KEATING LAURIESVP, GC & Secretary
Exercise / conversionCommon Stock 6,249 $42.22 $263,832.78
Disclosure

SEC source: 0001325812-17-000038 · primary_doc.xml · nonDerivative · entry 1

KEATING LAURIE · CIK 0001620743 · SVP, GC & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,749

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 22, 2017.

Read SEC document
December 20, 2017 Filed Dec 21, 2017 21:45 UTC GrantPerformance Based Stock Option 2016 (right to buy) · Derivative 6,250 $0.00 Strike: $42.22 $0.00
Disclosure

SEC source: 0001325812-17-000037 · primary_doc.xml · derivative · entry 3

Vaishnaw Akshay · CIK 0001458494 · EVP, R&D

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,250

Underlying: Common Stock · 6,250 shares

Expires 2026-12-20

F2 · kind: On December 20, 2016, the reporting person was granted a performance based stock option to purchase shares of ALNY common stock. One quarter of the shares subject to the option will vest upon the achievement of each of four specific clinical development, regulatory or commercial events, as approved by our compensation committee. Effective December 20, 2017, the compensation committee of the Company determined the first performance criterion had been met and the option vested as to one-quarter of the shares.

Read SEC document
December 20, 2017 Filed Dec 21, 2017 21:36 UTC
MARAGANORE JOHNDirector · Chief Executive Officer
GrantPerformance Based Stock Option 2016 (right to buy) · Derivative 6,250 $0.00 Strike: $42.22 $0.00
Disclosure

SEC source: 0001325812-17-000035 · primary_doc.xml · derivative · entry 3

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,250

Underlying: Common Stock · 6,250 shares

Expires 2026-12-20

F2 · kind: On December 20, 2016, the reporting person was granted a performance based stock option to purchase shares of ALNY common stock. One quarter of the shares subject to the option will vest upon the achievement of each of four specific clinical development, regulatory or commercial events, as approved by our compensation committee. Effective December 20, 2017, the compensation committee of the Company determined the first performance criterion had been met and the option vested as to one-quarter of the shares.

Read SEC document
December 20, 2017 Filed Dec 21, 2017 21:37 UTC GrantPerformance Stock Option 2016 (right to buy) · Derivative 6,250 $0.00 Strike: $42.22 $0.00
Disclosure

SEC source: 0001325812-17-000036 · edgardoc.xml · derivative · entry 1

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,250

Underlying: Common Stock · 6,250 shares

Expires 2026-12-20

F1 · kind: On December 20, 2016, the reporting person was granted a performance based stock option to purchase shares of ALNY common stock. One quarter of the shares subject to the option will vest upon the achievement of each of four specific clinical development, regulatory or commercial events, as approved by our compensation committee. Effective December 20, 2017, the compensation committee of the Company determined the first performance criterion had been met and the option vested as to one-quarter of the shares.

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December 19, 2017 Filed Dec 21, 2017 21:45 UTC GiftCommon Stock 320 $0.00 $0.00
Disclosure

SEC source: 0001325812-17-000037 · primary_doc.xml · nonDerivative · entry 1

Vaishnaw Akshay · CIK 0001458494 · EVP, R&D

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,215

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December 19, 2017 Filed Dec 21, 2017 21:36 UTC
MARAGANORE JOHNDirector · Chief Executive Officer
Exercise / conversionStock Option (right to buy) · Derivative 1,587 $0.00 Strike: $63.00 $0.00
Disclosure

SEC source: 0001325812-17-000035 · primary_doc.xml · derivative · entry 4

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 148,413

Underlying: Common Stock · 1,587 shares

Expires 2023-12-18

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: The stock option vests as to 25% of the shares on the 1st anniversary of the date of the stock option grant and as to an additional 6.25% of the shares each successive three month period thereafter

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December 19, 2017 Filed Dec 21, 2017 21:36 UTC
MARAGANORE JOHNDirector · Chief Executive Officer
Exercise / conversionCommon Stock 1,587 $63.00 $99,981.00
Disclosure

SEC source: 0001325812-17-000035 · primary_doc.xml · nonDerivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 151,297

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

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December 01, 2017 Filed Dec 5, 2017 22:47 UTC
KEATING LAURIESVP, GC and Secretary
Exercise / conversionStock Option (Right to Buy) · Derivative 30,000 $0.00 Strike: $77.40 $0.00
Disclosure

SEC source: 0001553878-17-000070 · primary_doc.xml · derivative · entry 8

KEATING LAURIE · CIK 0001620743 · SVP, GC and Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 95,000

Underlying: Common Stock · 30,000 shares

Expires 2024-09-22

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 22, 2017.

F8 · derivative.exercise_date: The stock option vests as to 25% of the shares on the first anniversary of the date of the stock option grant and as to an additional 6.25% of the shares each successive three month period thereafter.

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December 01, 2017 Filed Dec 5, 2017 22:47 UTC
KEATING LAURIESVP, GC and Secretary
SaleCommon Stock 6,199 $137.29 $851,060.71
Disclosure

SEC source: 0001553878-17-000070 · primary_doc.xml · nonDerivative · entry 6

KEATING LAURIE · CIK 0001620743 · SVP, GC and Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,500

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 22, 2017.

F6 · price: Sale prices ranged from $137.04 to $137.73.

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December 01, 2017 Filed Dec 5, 2017 22:47 UTC
KEATING LAURIESVP, GC and Secretary
SaleCommon Stock 9,700 $136.50 $1,324,050.00
Disclosure

SEC source: 0001553878-17-000070 · primary_doc.xml · nonDerivative · entry 5

KEATING LAURIE · CIK 0001620743 · SVP, GC and Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,699

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 22, 2017.

F5 · price: Sale prices ranged from $136.00 to $136.95.

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December 01, 2017 Filed Dec 5, 2017 22:47 UTC
KEATING LAURIESVP, GC and Secretary
SaleCommon Stock 7,500 $135.56 $1,016,700.00
Disclosure

SEC source: 0001553878-17-000070 · primary_doc.xml · nonDerivative · entry 4

KEATING LAURIE · CIK 0001620743 · SVP, GC and Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,399

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 22, 2017.

F4 · price: Sale prices ranged from $134.99 to $135.93.

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December 01, 2017 Filed Dec 5, 2017 22:47 UTC
KEATING LAURIESVP, GC and Secretary
SaleCommon Stock 3,801 $134.59 $511,576.59
Disclosure

SEC source: 0001553878-17-000070 · primary_doc.xml · nonDerivative · entry 3

KEATING LAURIE · CIK 0001620743 · SVP, GC and Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,899

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 22, 2017.

F3 · price: Sale prices ranged from $133.95 to $134.92.

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December 01, 2017 Filed Dec 5, 2017 22:47 UTC
KEATING LAURIESVP, GC and Secretary
SaleCommon Stock 2,800 $133.37 $373,436.00
Disclosure

SEC source: 0001553878-17-000070 · primary_doc.xml · nonDerivative · entry 2

KEATING LAURIE · CIK 0001620743 · SVP, GC and Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,700

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 22, 2017.

F2 · price: Sale prices ranged from $132.90 to $133.74.

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December 01, 2017 Filed Dec 5, 2017 22:47 UTC
KEATING LAURIESVP, GC and Secretary
Exercise / conversionCommon Stock 30,000 $77.40 $2,322,000.00
Disclosure

SEC source: 0001553878-17-000070 · primary_doc.xml · nonDerivative · entry 1

KEATING LAURIE · CIK 0001620743 · SVP, GC and Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,500

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 22, 2017.

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November 22, 2017 Filed Nov 24, 2017 23:55 UTC
MARAGANORE JOHNDirector · Chief Executive Officer
Exercise / conversionStock Option (Right to Buy) · Derivative 73,415 $0.00 Strike: $31.39 $0.00
Disclosure

SEC source: 0001553878-17-000069 · primary_doc.xml · derivative · entry 7

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 73,415 shares

Expires 2017-12-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 13, 2017. The 73,415 options exercised and sold by the reporting person were due to expire on December 12, 2017.

F7 · derivative.exercise_date: The stock option vested as to 25% of the shares on the first anniversary of the date of the stock option grant and as to an additional 6.25% of the shares each successive three month period thereafter.

F1 · derivative.expiration_date: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 13, 2017. The 73,415 options exercised and sold by the reporting person were due to expire on December 12, 2017.

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November 22, 2017 Filed Nov 24, 2017 23:55 UTC
MARAGANORE JOHNDirector · Chief Executive Officer
SaleCommon Stock 2,683 $132.73 $356,114.59
Disclosure

SEC source: 0001553878-17-000069 · primary_doc.xml · nonDerivative · entry 5

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 149,710

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 13, 2017. The 73,415 options exercised and sold by the reporting person were due to expire on December 12, 2017.

F5 · price: Sale prices ranged from $132.38 to $133.34.

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November 22, 2017 Filed Nov 24, 2017 23:55 UTC
MARAGANORE JOHNDirector · Chief Executive Officer
SaleCommon Stock 20,433 $131.82 $2,693,478.06
Disclosure

SEC source: 0001553878-17-000069 · primary_doc.xml · nonDerivative · entry 4

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 152,393

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 13, 2017. The 73,415 options exercised and sold by the reporting person were due to expire on December 12, 2017.

F4 · price: Sale prices ranged from $131.38 to $132.36.

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November 22, 2017 Filed Nov 24, 2017 23:55 UTC
MARAGANORE JOHNDirector · Chief Executive Officer
SaleCommon Stock 25,036 $130.88 $3,276,711.68
Disclosure

SEC source: 0001553878-17-000069 · primary_doc.xml · nonDerivative · entry 3

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 172,826

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 13, 2017. The 73,415 options exercised and sold by the reporting person were due to expire on December 12, 2017.

F3 · price: Sale prices ranged from $130.38 to $131.37.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.