Last 12 months
Inside the activity.
0 purchase rows · 39 sale rows
Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.Monthly counts
| Month | Purchases | Sales |
|---|---|---|
| Nov 2025 | 0 | 2 |
| Dec 2025 | 0 | 6 |
| Jan 2026 | 0 | 1 |
| Feb 2026 | 0 | 0 |
| Mar 2026 | 0 | 21 |
| Apr 2026 | 0 | 7 |
| May 2026 | 0 | 0 |
| Jun 2026 | 0 | 0 |
| Jul 2026 | 0 | 1 |
| Aug 2026 | 0 | 1 |
| Sep 2026 | 0 | 0 |
| Oct 2026 | 0 | 0 |
Latest available
Insider transactions
Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”
The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.
| Transaction date | Owner / reported role | Activity / security | Shares / units | Reported price | Reported value | Details |
|---|---|---|---|---|---|---|
| August 11, 2025 Filed Aug 13, 2025 20:55 UTC |
Smith CynthiaDirector
|
Exercise / conversionRestricted stock units · Derivative | 2,302 | $0.00 | $0.00 |
DisclosureSEC source: 0001439222-25-000097 · wk-form4_1755118521.xml · derivative · entry 2 Smith Cynthia · CIK 0001609480 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 0 Underlying: Common stock · 2,302 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock. F2 · derivative.exercise_date: The restricted stock units were granted on August 11, 2022. Beginning on August 11, 2023, the shares underlying the restricted stock units will vest in three equal annual installments. F2 · derivative.expiration_date: The restricted stock units were granted on August 11, 2022. Beginning on August 11, 2023, the shares underlying the restricted stock units will vest in three equal annual installments. Read SEC document |
| August 11, 2025 Filed Aug 13, 2025 20:55 UTC |
Smith CynthiaDirector
|
Exercise / conversionCommon stock | 2,302 | $0.00 | $0.00 |
DisclosureSEC source: 0001439222-25-000097 · wk-form4_1755118521.xml · nonDerivative · entry 1 Smith Cynthia · CIK 0001609480 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 12,414 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| August 08, 2025 Filed Aug 12, 2025 20:24 UTC |
Goff BrianDirector · Chief Executive Officer
|
Exercise / conversionRestricted stock units · Derivative | 22,691 | $0.00 | $0.00 |
DisclosureSEC source: 0001439222-25-000093 · wk-form4_1755030260.xml · derivative · entry 3 Goff Brian · CIK 0001546216 · Director · Chief Executive Officer 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 0 Underlying: Common stock · 22,691 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock. F3 · derivative.exercise_date: The restricted stock units were granted on August 8, 2022. Beginning on August 8, 2023, the shares underlying the restricted stock units will vest in three equal annual installments. F3 · derivative.expiration_date: The restricted stock units were granted on August 8, 2022. Beginning on August 8, 2023, the shares underlying the restricted stock units will vest in three equal annual installments. Read SEC document |
| August 08, 2025 Filed Aug 12, 2025 20:24 UTC |
Goff BrianDirector · Chief Executive Officer
|
SaleCommon stock | 11,085 | $36.67 | $406,486.95 |
DisclosureSEC source: 0001439222-25-000093 · wk-form4_1755030260.xml · nonDerivative · entry 2 Goff Brian · CIK 0001546216 · Director · Chief Executive Officer 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 123,528 F1 · kind: Shares sold to cover the tax withholding obligation in respect of vesting of the reporting person's restricted stock units. This transaction was effected pursuant to durable automatic sale instructions consistent with the affirmative defense to liability under Section 10(b) of the Securities Exchange Act of 1934 under Rule 10b5-1(c) promulgated under such Act. Such instructions were included in the reporting person's restricted stock unit agreement dated August 8, 2022. Read SEC document |
| August 08, 2025 Filed Aug 12, 2025 20:24 UTC |
Goff BrianDirector · Chief Executive Officer
|
Exercise / conversionCommon stock | 22,691 | $0.00 | $0.00 |
DisclosureSEC source: 0001439222-25-000093 · wk-form4_1755030260.xml · nonDerivative · entry 1 Goff Brian · CIK 0001546216 · Director · Chief Executive Officer 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 134,613 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| July 10, 2025 Filed Jul 15, 2025 20:05 UTC |
Scadden DavidDirector
|
Exercise / conversionStock options (right to buy) · Derivative | 1,400 | $0.00 Strike: $18.09 | $0.00 |
DisclosureSEC source: 0001439222-25-000084 · wk-form4_1752609950.xml · derivative · entry 3 Scadden David · CIK 0001707715 · Director 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 27,707 Underlying: Common stock · 1,400 shares Expires 2032-06-21 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F2 · derivative.exercise_date: This option was granted on June 21, 2022. The shares underlying this option vest 100% one year from grant date. Read SEC document |
| July 10, 2025 Filed Jul 15, 2025 20:05 UTC |
Scadden DavidDirector
|
SaleCommon stock | 1,400 | $40.00 | $56,000.00 |
DisclosureSEC source: 0001439222-25-000084 · wk-form4_1752609950.xml · nonDerivative · entry 2 Scadden David · CIK 0001707715 · Director 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 17,603 F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. Read SEC document |
| July 10, 2025 Filed Jul 15, 2025 20:05 UTC |
Scadden DavidDirector
|
Exercise / conversionCommon stock | 1,400 | $18.09 | $25,326.00 |
DisclosureSEC source: 0001439222-25-000084 · wk-form4_1752609950.xml · nonDerivative · entry 1 Scadden David · CIK 0001707715 · Director 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 19,003 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. Read SEC document |
| July 09, 2025 Filed Jul 11, 2025 20:59 UTC |
Gheuens SarahChief Medical Officer
|
Exercise / conversionStock options (right to buy) · Derivative | 11,914 | $0.00 Strike: $25.01 | $0.00 |
DisclosureSEC source: 0001439222-25-000082 · wk-form4_1752267546.xml · derivative · entry 4 Gheuens Sarah · CIK 0001881190 · Chief Medical Officer 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 32,086 Underlying: Common stock · 11,914 shares Expires 2033-03-01 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F4 · derivative.exercise_date: This option was originally granted on March 1, 2023 for the purchase of 44,000 shares of common stock. The shares underlying this option vest as to 25% of the underlying shares on March 1, 2024, with the remaining 75% vesting in 36 equal monthly installments thereafter. Read SEC document |
| July 09, 2025 Filed Jul 11, 2025 20:59 UTC |
Gheuens SarahChief Medical Officer
|
SaleCommon stock | 847 | $38.76 | $32,829.72 |
DisclosureSEC source: 0001439222-25-000082 · wk-form4_1752267546.xml · nonDerivative · entry 3 Gheuens Sarah · CIK 0001881190 · Chief Medical Officer 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 61,271 F1 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F3 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $38.55 to $38.87. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. Read SEC document |
| July 09, 2025 Filed Jul 11, 2025 20:59 UTC |
Gheuens SarahChief Medical Officer
|
SaleCommon stock | 11,067 | $37.93 | $419,771.31 |
DisclosureSEC source: 0001439222-25-000082 · wk-form4_1752267546.xml · nonDerivative · entry 2 Gheuens Sarah · CIK 0001881190 · Chief Medical Officer 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 62,118 F1 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F2 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $37.52 to $38.49. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. Read SEC document |
| July 09, 2025 Filed Jul 11, 2025 20:59 UTC |
Gheuens SarahChief Medical Officer
|
Exercise / conversionCommon stock | 11,914 | $25.01 | $297,969.14 |
DisclosureSEC source: 0001439222-25-000082 · wk-form4_1752267546.xml · nonDerivative · entry 1 Gheuens Sarah · CIK 0001881190 · Chief Medical Officer 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 73,185 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| July 08, 2025 Filed Jul 10, 2025 20:14 UTC |
Backstrom Jay T.Director
|
GrantRestricted stock units · Derivative | 4,341 | $0.00 | $0.00 |
DisclosureSEC source: 0001439222-25-000080 · wk-form4_1752178459.xml · derivative · entry 2 Backstrom Jay T. · CIK 0001796398 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 4,341 Underlying: Common stock · 4,341 shares Expires not disclosed F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock. F3 · derivative.exercise_date: The restricted stock units were granted on July 8, 2025. Beginning on July 8, 2026, the shares underlying the restricted stock units will vest in three equal annual installments. F3 · derivative.expiration_date: The restricted stock units were granted on July 8, 2025. Beginning on July 8, 2026, the shares underlying the restricted stock units will vest in three equal annual installments. Read SEC document |
| July 08, 2025 Filed Jul 10, 2025 20:14 UTC |
Backstrom Jay T.Director
|
GrantStock options (right to buy) · Derivative | 23,393 | $0.00 Strike: $36.28 | $0.00 |
DisclosureSEC source: 0001439222-25-000080 · wk-form4_1752178459.xml · derivative · entry 1 Backstrom Jay T. · CIK 0001796398 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 23,393 Underlying: Common stock · 23,393 shares Expires 2035-07-08 F1 · derivative.exercise_date: This option was granted on July 8, 2025. The shares underlying this option vest as to 25% of the underlying shares on July 8, 2026, with the remaining 75% vesting in 36 equal monthly installments thereafter. Read SEC document |
| July 01, 2025 Filed Jul 3, 2025 20:01 UTC |
Gheuens SarahChief Medical Officer
|
Exercise / conversionRestricted stock units · Derivative | 8,374 | $0.00 | $0.00 |
DisclosureSEC source: 0001439222-25-000073 · wk-form4_1751572884.xml · derivative · entry 3 Gheuens Sarah · CIK 0001881190 · Chief Medical Officer 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 8,375 Underlying: Common stock · 8,374 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock. F3 · derivative.exercise_date: The restricted stock units were granted on July 1, 2023. Beginning on July 1, 2024, the shares underlying the restricted stock units will vest in three equal annual installments. F3 · derivative.expiration_date: The restricted stock units were granted on July 1, 2023. Beginning on July 1, 2024, the shares underlying the restricted stock units will vest in three equal annual installments. Read SEC document |
| July 01, 2025 Filed Jul 3, 2025 20:01 UTC |
Gheuens SarahChief Medical Officer
|
SaleCommon stock | 4,091 | $34.17 | $139,789.47 |
DisclosureSEC source: 0001439222-25-000073 · wk-form4_1751572884.xml · nonDerivative · entry 2 Gheuens Sarah · CIK 0001881190 · Chief Medical Officer 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 61,271 F1 · kind: Shares sold to cover the tax withholding obligation in respect of vesting of the reporting person's restricted share units. This transaction was effected pursuant to durable automatic sale instructions consistent with the affirmative defense to liability under Section 10(b) of the Securities Exchange Act of 1934 under Rule 10b5-1(c) promulgated under such Act. Such instructions were included in the reporting person's restricted stock unit agreement dated July 1, 2023. Read SEC document |
| July 01, 2025 Filed Jul 3, 2025 20:01 UTC |
Gheuens SarahChief Medical Officer
|
Exercise / conversionCommon stock | 8,374 | $0.00 | $0.00 |
DisclosureSEC source: 0001439222-25-000073 · wk-form4_1751572884.xml · nonDerivative · entry 1 Gheuens Sarah · CIK 0001881190 · Chief Medical Officer 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 65,362 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| June 24, 2025 Filed Jun 26, 2025 21:23 UTC |
Milanova TsvetaChief Commercial Officer
|
Exercise / conversionPerformance share units · Derivative | 6,000 | $0.00 | $0.00 |
DisclosureSEC source: 0001439222-25-000065 · wk-form4_1750972990.xml · derivative · entry 3 Milanova Tsveta · CIK 0001957180 · Chief Commercial Officer 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 6,000 Underlying: Common stock · 6,000 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F2 · derivative.exercise_price: Each performance share unit represents a contingent right to receive one share of the issuer's common stock. F3 · derivative.exercise_date: The PSUs were granted on March 1, 2023. The PSUs vest as to 50% of the underlying shares upon the achievement of a specified research milestone and as to the remaining 50% of the underlying shares upon the achievement of a specified regulatory milestone. The performance criteria for the specified research milestone was determined to have been met on June 24, 2025, resulting in the vesting of the PSUs as to 50% of the underlying shares. Vested shares will be delivered to the reporting person within three business days after such shares become vested. F3 · derivative.expiration_date: The PSUs were granted on March 1, 2023. The PSUs vest as to 50% of the underlying shares upon the achievement of a specified research milestone and as to the remaining 50% of the underlying shares upon the achievement of a specified regulatory milestone. The performance criteria for the specified research milestone was determined to have been met on June 24, 2025, resulting in the vesting of the PSUs as to 50% of the underlying shares. Vested shares will be delivered to the reporting person within three business days after such shares become vested. Read SEC document |
| June 24, 2025 Filed Jun 26, 2025 21:23 UTC |
Milanova TsvetaChief Commercial Officer
|
SaleCommon stock | 2,770 | $33.54 | $92,905.80 |
DisclosureSEC source: 0001439222-25-000065 · wk-form4_1750972990.xml · nonDerivative · entry 2 Milanova Tsveta · CIK 0001957180 · Chief Commercial Officer 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 26,122 F1 · kind: Shares sold to cover the tax withholding obligation in respect of vesting of the reporting person's performance share units. This transaction was effected pursuant to durable automatic sale instructions consistent with the affirmative defense to liability under Section 10(b) of the Securities Exchange Act of 1934 under Rule 10b5-1(c) promulgated under such Act. Such instructions were included in the reporting person's performance share unit agreement dated March 1, 2023. Read SEC document |
| June 24, 2025 Filed Jun 26, 2025 21:23 UTC |
Milanova TsvetaChief Commercial Officer
|
Exercise / conversionCommon stock | 6,000 | $0.00 | $0.00 |
DisclosureSEC source: 0001439222-25-000065 · wk-form4_1750972990.xml · nonDerivative · entry 1 Milanova Tsveta · CIK 0001957180 · Chief Commercial Officer 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 28,892 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| June 24, 2025 Filed Jun 26, 2025 21:25 UTC |
Gheuens SarahChief Medical Officer
|
Exercise / conversionPerformance share units · Derivative | 6,000 | $0.00 | $0.00 |
DisclosureSEC source: 0001439222-25-000069 · wk-form4_1750973125.xml · derivative · entry 3 Gheuens Sarah · CIK 0001881190 · Chief Medical Officer 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 6,000 Underlying: Common stock · 6,000 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F2 · derivative.exercise_price: Each performance share unit represents a contingent right to receive one share of the issuer's common stock. F3 · derivative.exercise_date: The PSUs were granted on March 1, 2023. The PSUs vest as to 50% of the underlying shares upon the achievement of a specified research milestone and as to the remaining 50% of the underlying shares upon the achievement of a specified regulatory milestone. The performance criteria for the specified research milestone was determined to have been met on June 24, 2025, resulting in the vesting of the PSUs as to 50% of the underlying shares. Vested shares will be delivered to the reporting person within three business days after such shares become vested. F3 · derivative.expiration_date: The PSUs were granted on March 1, 2023. The PSUs vest as to 50% of the underlying shares upon the achievement of a specified research milestone and as to the remaining 50% of the underlying shares upon the achievement of a specified regulatory milestone. The performance criteria for the specified research milestone was determined to have been met on June 24, 2025, resulting in the vesting of the PSUs as to 50% of the underlying shares. Vested shares will be delivered to the reporting person within three business days after such shares become vested. Read SEC document |
| June 24, 2025 Filed Jun 26, 2025 21:25 UTC |
Gheuens SarahChief Medical Officer
|
SaleCommon stock | 2,909 | $33.54 | $97,567.86 |
DisclosureSEC source: 0001439222-25-000069 · wk-form4_1750973125.xml · nonDerivative · entry 2 Gheuens Sarah · CIK 0001881190 · Chief Medical Officer 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 56,988 F1 · kind: Shares sold to cover the tax withholding obligation in respect of vesting of the reporting person's performance share units. This transaction was effected pursuant to durable automatic sale instructions consistent with the affirmative defense to liability under Section 10(b) of the Securities Exchange Act of 1934 under Rule 10b5-1(c) promulgated under such Act. Such instructions were included in the reporting person's performance share unit agreement dated March 1, 2023. Read SEC document |
| June 24, 2025 Filed Jun 26, 2025 21:25 UTC |
Gheuens SarahChief Medical Officer
|
Exercise / conversionCommon stock | 6,000 | $0.00 | $0.00 |
DisclosureSEC source: 0001439222-25-000069 · wk-form4_1750973125.xml · nonDerivative · entry 1 Gheuens Sarah · CIK 0001881190 · Chief Medical Officer 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 59,897 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| June 24, 2025 Filed Jun 26, 2025 21:26 UTC |
Burns James WilliamChief Legal Officer
|
Exercise / conversionPerformance share units · Derivative | 6,000 | $0.00 | $0.00 |
DisclosureSEC source: 0001439222-25-000071 · wk-form4_1750973184.xml · derivative · entry 3 Burns James William · CIK 0001900772 · Chief Legal Officer 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 6,000 Underlying: Common stock · 6,000 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F2 · derivative.exercise_price: Each performance share unit represents a contingent right to receive one share of the issuer's common stock. F3 · derivative.exercise_date: The PSUs were granted on March 1, 2023. The PSUs vest as to 50% of the underlying shares upon the achievement of a specified research milestone and as to the remaining 50% of the underlying shares upon the achievement of a specified regulatory milestone. The performance criteria for the specified research milestone was determined to have been met on June 24, 2025, resulting in the vesting of the PSUs as to 50% of the underlying shares. Vested shares will be delivered to the reporting person within three business days after such shares become vested. F3 · derivative.expiration_date: The PSUs were granted on March 1, 2023. The PSUs vest as to 50% of the underlying shares upon the achievement of a specified research milestone and as to the remaining 50% of the underlying shares upon the achievement of a specified regulatory milestone. The performance criteria for the specified research milestone was determined to have been met on June 24, 2025, resulting in the vesting of the PSUs as to 50% of the underlying shares. Vested shares will be delivered to the reporting person within three business days after such shares become vested. Read SEC document |
| June 24, 2025 Filed Jun 26, 2025 21:26 UTC |
Burns James WilliamChief Legal Officer
|
SaleCommon stock | 2,799 | $33.54 | $93,878.46 |
DisclosureSEC source: 0001439222-25-000071 · wk-form4_1750973184.xml · nonDerivative · entry 2 Burns James William · CIK 0001900772 · Chief Legal Officer 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 28,650 F1 · kind: Shares sold to cover the tax withholding obligation in respect of vesting of the reporting person's performance share units. This transaction was effected pursuant to durable automatic sale instructions consistent with the affirmative defense to liability under Section 10(b) of the Securities Exchange Act of 1934 under Rule 10b5-1(c) promulgated under such Act. Such instructions were included in the reporting person's performance share unit agreement dated March 1, 2023. Read SEC document |
| June 24, 2025 Filed Jun 26, 2025 21:26 UTC |
Burns James WilliamChief Legal Officer
|
Exercise / conversionCommon stock | 6,000 | $0.00 | $0.00 |
DisclosureSEC source: 0001439222-25-000071 · wk-form4_1750973184.xml · nonDerivative · entry 1 Burns James William · CIK 0001900772 · Chief Legal Officer 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 31,449 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| June 24, 2025 Filed Jun 26, 2025 21:24 UTC |
Jones CeciliaChief Financial Officer
|
Exercise / conversionPerformance share units · Derivative | 6,000 | $0.00 | $0.00 |
DisclosureSEC source: 0001439222-25-000067 · wk-form4_1750973073.xml · derivative · entry 3 Jones Cecilia · CIK 0001840056 · Chief Financial Officer 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 6,000 Underlying: Common stock · 6,000 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F2 · derivative.exercise_price: Each performance share unit represents a contingent right to receive one share of the issuer's common stock. F3 · derivative.exercise_date: The PSUs were granted on March 1, 2023. The PSUs vest as to 50% of the underlying shares upon the achievement of a specified research milestone and as to the remaining 50% of the underlying shares upon the achievement of a specified regulatory milestone. The performance criteria for the specified research milestone was determined to have been met on June 24, 2025, resulting in the vesting of the PSUs as to 50% of the underlying shares. Vested shares will be delivered to the reporting person within three business days after such shares become vested. F3 · derivative.expiration_date: The PSUs were granted on March 1, 2023. The PSUs vest as to 50% of the underlying shares upon the achievement of a specified research milestone and as to the remaining 50% of the underlying shares upon the achievement of a specified regulatory milestone. The performance criteria for the specified research milestone was determined to have been met on June 24, 2025, resulting in the vesting of the PSUs as to 50% of the underlying shares. Vested shares will be delivered to the reporting person within three business days after such shares become vested. Read SEC document |
| June 24, 2025 Filed Jun 26, 2025 21:24 UTC |
Jones CeciliaChief Financial Officer
|
SaleCommon stock | 1,780 | $33.54 | $59,701.20 |
DisclosureSEC source: 0001439222-25-000067 · wk-form4_1750973073.xml · nonDerivative · entry 2 Jones Cecilia · CIK 0001840056 · Chief Financial Officer 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 30,049 F1 · kind: Shares sold to cover the tax withholding obligation in respect of vesting of the reporting person's performance share units. This transaction was effected pursuant to durable automatic sale instructions consistent with the affirmative defense to liability under Section 10(b) of the Securities Exchange Act of 1934 under Rule 10b5-1(c) promulgated under such Act. Such instructions were included in the reporting person's performance share unit agreement dated March 1, 2023. Read SEC document |
| June 24, 2025 Filed Jun 26, 2025 21:24 UTC |
Jones CeciliaChief Financial Officer
|
Exercise / conversionCommon stock | 6,000 | $0.00 | $0.00 |
DisclosureSEC source: 0001439222-25-000067 · wk-form4_1750973073.xml · nonDerivative · entry 1 Jones Cecilia · CIK 0001840056 · Chief Financial Officer 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 31,829 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| June 24, 2025 Filed Jun 26, 2025 21:22 UTC |
Goff BrianDirector · Chief Executive Officer
|
Exercise / conversionPerformance share units · Derivative | 12,750 | $0.00 | $0.00 |
DisclosureSEC source: 0001439222-25-000063 · wk-form4_1750972918.xml · derivative · entry 6 Goff Brian · CIK 0001546216 · Director · Chief Executive Officer 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 12,750 Underlying: Common stock · 12,750 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F3 · derivative.exercise_price: Each performance share unit represents a contingent right to receive one share of the issuer's common stock. F5 · derivative.exercise_date: The PSUs were granted on March 1, 2023. The PSUs vest as to 50% of the underlying shares upon the achievement of a specified research milestone and as to the remaining 50% of the underlying shares upon the achievement of a specified regulatory milestone. The performance criteria for the specified research milestone was determined to have been met on June 24, 2025, resulting in the vesting of the PSUs as to 50% of the underlying shares. Vested shares will be delivered to the reporting person within three business days after such shares become vested. F5 · derivative.expiration_date: The PSUs were granted on March 1, 2023. The PSUs vest as to 50% of the underlying shares upon the achievement of a specified research milestone and as to the remaining 50% of the underlying shares upon the achievement of a specified regulatory milestone. The performance criteria for the specified research milestone was determined to have been met on June 24, 2025, resulting in the vesting of the PSUs as to 50% of the underlying shares. Vested shares will be delivered to the reporting person within three business days after such shares become vested. Read SEC document |
| June 24, 2025 Filed Jun 26, 2025 21:22 UTC |
Goff BrianDirector · Chief Executive Officer
|
Exercise / conversionPerformance share units · Derivative | 25,527 | $0.00 | $0.00 |
DisclosureSEC source: 0001439222-25-000063 · wk-form4_1750972918.xml · derivative · entry 5 Goff Brian · CIK 0001546216 · Director · Chief Executive Officer 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 51,056 Underlying: Common stock · 25,527 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F3 · derivative.exercise_price: Each performance share unit represents a contingent right to receive one share of the issuer's common stock. F4 · derivative.exercise_date: The PSUs were granted on August 8, 2022. The PSUs vest as to 15% of the underlying shares upon the achievement of a specified research milestone and as to the remaining underlying shares upon the achievement of other clinical and regulatory milestones. The performance criteria for the specified research milestone was determined to have been met on June 24, 2025, resulting in the vesting of the PSUs as to 15% of the underlying shares of common stock. Vested shares will be delivered to the reporting person within three business days after such shares become vested. F4 · derivative.expiration_date: The PSUs were granted on August 8, 2022. The PSUs vest as to 15% of the underlying shares upon the achievement of a specified research milestone and as to the remaining underlying shares upon the achievement of other clinical and regulatory milestones. The performance criteria for the specified research milestone was determined to have been met on June 24, 2025, resulting in the vesting of the PSUs as to 15% of the underlying shares of common stock. Vested shares will be delivered to the reporting person within three business days after such shares become vested. Read SEC document |
| June 24, 2025 Filed Jun 26, 2025 21:22 UTC |
Goff BrianDirector · Chief Executive Officer
|
SaleCommon stock | 6,229 | $33.54 | $208,920.66 |
DisclosureSEC source: 0001439222-25-000063 · wk-form4_1750972918.xml · nonDerivative · entry 4 Goff Brian · CIK 0001546216 · Director · Chief Executive Officer 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 111,922 F2 · kind: Shares sold to cover the tax withholding obligation in respect of vesting of the reporting person's performance share units. This transaction was effected pursuant to durable automatic sale instructions consistent with the affirmative defense to liability under Section 10(b) of the Securities Exchange Act of 1934 under Rule 10b5-1(c) promulgated under such Act. Such instructions were included in the reporting person's performance share unit agreement dated March 1, 2023. Read SEC document |
| June 24, 2025 Filed Jun 26, 2025 21:22 UTC |
Goff BrianDirector · Chief Executive Officer
|
Exercise / conversionCommon stock | 12,750 | $0.00 | $0.00 |
DisclosureSEC source: 0001439222-25-000063 · wk-form4_1750972918.xml · nonDerivative · entry 3 Goff Brian · CIK 0001546216 · Director · Chief Executive Officer 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 118,151 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| June 24, 2025 Filed Jun 26, 2025 21:22 UTC |
Goff BrianDirector · Chief Executive Officer
|
SaleCommon stock | 12,471 | $33.54 | $418,277.34 |
DisclosureSEC source: 0001439222-25-000063 · wk-form4_1750972918.xml · nonDerivative · entry 2 Goff Brian · CIK 0001546216 · Director · Chief Executive Officer 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 105,401 F1 · kind: Shares sold to cover the tax withholding obligation in respect of vesting of the reporting person's performance share units. This transaction was effected pursuant to durable automatic sale instructions consistent with the affirmative defense to liability under Section 10(b) of the Securities Exchange Act of 1934 under Rule 10b5-1(c) promulgated under such Act. Such instructions were included in the reporting person's performance share unit agreement dated August 8, 2022. Read SEC document |
| June 24, 2025 Filed Jun 26, 2025 21:22 UTC |
Goff BrianDirector · Chief Executive Officer
|
Exercise / conversionCommon stock | 25,527 | $0.00 | $0.00 |
DisclosureSEC source: 0001439222-25-000063 · wk-form4_1750972918.xml · nonDerivative · entry 1 Goff Brian · CIK 0001546216 · Director · Chief Executive Officer 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 117,872 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| June 20, 2025 Filed Jun 23, 2025 20:20 UTC |
Owen Adams CatherineDirector
|
Exercise / conversionRestricted stock units · Derivative | 2,120 | $0.00 | $0.00 |
DisclosureSEC source: 0001439222-25-000051 · wk-form4_1750710009.xml · derivative · entry 4 Owen Adams Catherine · CIK 0001816838 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 0 Underlying: Common stock · 2,120 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock. F4 · derivative.exercise_date: The restricted stock units were granted on June 20, 2024. The shares underlying the stock units vest in full on June 20, 2025. Vested shares will be delivered to the reporting person within three business days after such shares become vested. F4 · derivative.expiration_date: The restricted stock units were granted on June 20, 2024. The shares underlying the stock units vest in full on June 20, 2025. Vested shares will be delivered to the reporting person within three business days after such shares become vested. Read SEC document |
| June 20, 2025 Filed Jun 23, 2025 20:20 UTC |
Owen Adams CatherineDirector
|
Exercise / conversionCommon stock | 2,120 | $0.00 | $0.00 |
DisclosureSEC source: 0001439222-25-000051 · wk-form4_1750710009.xml · nonDerivative · entry 1 Owen Adams Catherine · CIK 0001816838 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 6,073 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| June 20, 2025 Filed Jun 23, 2025 20:27 UTC |
Ballal Rahul D.Director
|
Exercise / conversionRestricted stock units · Derivative | 2,120 | $0.00 | $0.00 |
DisclosureSEC source: 0001439222-25-000061 · wk-form4_1750710427.xml · derivative · entry 4 Ballal Rahul D. · CIK 0001805097 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 0 Underlying: Common stock · 2,120 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock. F4 · derivative.exercise_date: The restricted stock units were granted on June 20, 2024. The shares underlying the stock units vest in full on June 20, 2025. Vested shares will be delivered to the reporting person within three business days after such shares become vested. F4 · derivative.expiration_date: The restricted stock units were granted on June 20, 2024. The shares underlying the stock units vest in full on June 20, 2025. Vested shares will be delivered to the reporting person within three business days after such shares become vested. Read SEC document |
| June 20, 2025 Filed Jun 23, 2025 20:27 UTC |
Ballal Rahul D.Director
|
Exercise / conversionCommon stock | 2,120 | $0.00 | $0.00 |
DisclosureSEC source: 0001439222-25-000061 · wk-form4_1750710427.xml · nonDerivative · entry 1 Ballal Rahul D. · CIK 0001805097 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 10,112 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| June 20, 2025 Filed Jun 23, 2025 20:25 UTC |
CAPELLO JEFFREY DDirector
|
Exercise / conversionRestricted stock units · Derivative | 2,120 | $0.00 | $0.00 |
DisclosureSEC source: 0001439222-25-000059 · wk-form4_1750710331.xml · derivative · entry 4 CAPELLO JEFFREY D · CIK 0001224108 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 0 Underlying: Common stock · 2,120 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock. F4 · derivative.exercise_date: The restricted stock units were granted on June 20, 2024. The shares underlying the stock units vest in full on June 20, 2025. Vested shares will be delivered to the reporting person within three business days after such shares become vested. F4 · derivative.expiration_date: The restricted stock units were granted on June 20, 2024. The shares underlying the stock units vest in full on June 20, 2025. Vested shares will be delivered to the reporting person within three business days after such shares become vested. Read SEC document |
| June 20, 2025 Filed Jun 23, 2025 20:25 UTC |
CAPELLO JEFFREY DDirector
|
Exercise / conversionCommon stock | 2,120 | $0.00 | $0.00 |
DisclosureSEC source: 0001439222-25-000059 · wk-form4_1750710331.xml · nonDerivative · entry 1 CAPELLO JEFFREY D · CIK 0001224108 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 6,073 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| June 20, 2025 Filed Jun 23, 2025 20:24 UTC |
Foster-Cheek Kaye IDirector
|
Exercise / conversionRestricted stock units · Derivative | 2,120 | $0.00 | $0.00 |
DisclosureSEC source: 0001439222-25-000057 · wk-form4_1750710263.xml · derivative · entry 5 Foster-Cheek Kaye I · CIK 0001312622 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 0 Underlying: Common stock · 2,120 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock. F4 · derivative.exercise_date: The restricted stock units were granted on June 20, 2024. The shares underlying the stock units vest in full on June 20, 2025. Vested shares will be delivered to the reporting person within three business days after such shares become vested. F4 · derivative.expiration_date: The restricted stock units were granted on June 20, 2024. The shares underlying the stock units vest in full on June 20, 2025. Vested shares will be delivered to the reporting person within three business days after such shares become vested. Read SEC document |
| June 20, 2025 Filed Jun 23, 2025 20:24 UTC |
Foster-Cheek Kaye IDirector
|
Exercise / conversionCommon stock | 2,120 | $0.00 | $0.00 |
DisclosureSEC source: 0001439222-25-000057 · wk-form4_1750710263.xml · nonDerivative · entry 1 Foster-Cheek Kaye I · CIK 0001312622 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 7,468 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| June 20, 2025 Filed Jun 23, 2025 20:23 UTC |
FOUSE JACQUALYN ADirector
|
Exercise / conversionRestricted stock units · Derivative | 2,120 | $0.00 | $0.00 |
DisclosureSEC source: 0001439222-25-000055 · wk-form4_1750710197.xml · derivative · entry 4 FOUSE JACQUALYN A · CIK 0001405288 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 0 Underlying: Common stock · 2,120 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock. F4 · derivative.exercise_date: The restricted stock units were granted on June 20, 2024. The shares underlying the stock units vest in full on June 20, 2025. Vested shares will be delivered to the reporting person within three business days after such shares become vested. F4 · derivative.expiration_date: The restricted stock units were granted on June 20, 2024. The shares underlying the stock units vest in full on June 20, 2025. Vested shares will be delivered to the reporting person within three business days after such shares become vested. Read SEC document |
| June 20, 2025 Filed Jun 23, 2025 20:23 UTC |
FOUSE JACQUALYN ADirector
|
Exercise / conversionCommon stock | 2,120 | $0.00 | $0.00 |
DisclosureSEC source: 0001439222-25-000055 · wk-form4_1750710197.xml · nonDerivative · entry 1 FOUSE JACQUALYN A · CIK 0001405288 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 151,340 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| June 20, 2025 Filed Jun 23, 2025 20:21 UTC |
Ho MaykinDirector
|
Exercise / conversionRestricted stock units · Derivative | 2,120 | $0.00 | $0.00 |
DisclosureSEC source: 0001439222-25-000053 · wk-form4_1750710074.xml · derivative · entry 4 Ho Maykin · CIK 0001646395 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 0 Underlying: Common stock · 2,120 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock. F4 · derivative.exercise_date: The restricted stock units were granted on June 20, 2024. The shares underlying the stock units vest in full on June 20, 2025. Vested shares will be delivered to the reporting person within three business days after such shares become vested. F4 · derivative.expiration_date: The restricted stock units were granted on June 20, 2024. The shares underlying the stock units vest in full on June 20, 2025. Vested shares will be delivered to the reporting person within three business days after such shares become vested. Read SEC document |
| June 20, 2025 Filed Jun 23, 2025 20:21 UTC |
Ho MaykinDirector
|
Exercise / conversionCommon stock | 2,120 | $0.00 | $0.00 |
DisclosureSEC source: 0001439222-25-000053 · wk-form4_1750710074.xml · nonDerivative · entry 1 Ho Maykin · CIK 0001646395 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 17,032 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| June 20, 2025 Filed Jun 23, 2025 20:17 UTC |
Smith CynthiaDirector
|
Exercise / conversionRestricted stock units · Derivative | 2,120 | $0.00 | $0.00 |
DisclosureSEC source: 0001439222-25-000047 · wk-form4_1750709855.xml · derivative · entry 4 Smith Cynthia · CIK 0001609480 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 0 Underlying: Common stock · 2,120 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock. F4 · derivative.exercise_date: The restricted stock units were granted on June 20, 2024. The shares underlying the stock units vest in full on June 20, 2025. Vested shares will be delivered to the reporting person within three business days after such shares become vested. F4 · derivative.expiration_date: The restricted stock units were granted on June 20, 2024. The shares underlying the stock units vest in full on June 20, 2025. Vested shares will be delivered to the reporting person within three business days after such shares become vested. Read SEC document |
| June 20, 2025 Filed Jun 23, 2025 20:17 UTC |
Smith CynthiaDirector
|
Exercise / conversionCommon stock | 2,120 | $0.00 | $0.00 |
DisclosureSEC source: 0001439222-25-000047 · wk-form4_1750709855.xml · nonDerivative · entry 1 Smith Cynthia · CIK 0001609480 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 10,112 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| June 20, 2025 Filed Jun 23, 2025 20:18 UTC |
Scadden DavidDirector
|
Exercise / conversionRestricted stock units · Derivative | 2,120 | $0.00 | $0.00 |
DisclosureSEC source: 0001439222-25-000049 · wk-form4_1750709929.xml · derivative · entry 4 Scadden David · CIK 0001707715 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 0 Underlying: Common stock · 2,120 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock. F4 · derivative.exercise_date: The restricted stock units were granted on June 20, 2024. The shares underlying the stock units vest in full on June 20, 2025. Vested shares will be delivered to the reporting person within three business days after such shares become vested. F4 · derivative.expiration_date: The restricted stock units were granted on June 20, 2024. The shares underlying the stock units vest in full on June 20, 2025. Vested shares will be delivered to the reporting person within three business days after such shares become vested. Read SEC document |
Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.