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Nasdaq · USD

AGIO

AGIOS PHARMACEUTICALS, INC.

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Tapewire entity
4499
SEC CIK
0001439222
Parsed reports
520

Last 12 months

Inside the activity.

0 purchase rows · 39 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
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MonthPurchasesSales
Nov 202502
Dec 202506
Jan 202601
Feb 202600
Mar 2026021
Apr 202607
May 202600
Jun 202600
Jul 202601
Aug 202601
Sep 202600
Oct 202600

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
February 16, 2018 Filed Feb 20, 2018 21:03 UTC
Bowden ChristopherChief Medical Officer
Exercise / conversionStock option (right to buy) · Derivative 2,000 $0.00 Strike: $35.16 $0.00
Disclosure

SEC source: 0001209191-18-011244 · doc4.xml · derivative · entry 4

Bowden Christopher · CIK 0001608601 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 105,000

Underlying: Common stock · 2,000 shares

Expires 2024-05-30

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F5 · derivative.exercise_date: This option was granted on May 31, 2014. The shares underlying this option vest as to 25% of the underlying shares on May 13, 2015, with the remaining 75% vesting in 36 equal monthly installments thereafter.

Read SEC document
February 16, 2018 Filed Feb 20, 2018 21:03 UTC
Bowden ChristopherChief Medical Officer
SaleCommon stock 500 $78.08 $39,040.00
Disclosure

SEC source: 0001209191-18-011244 · doc4.xml · nonDerivative · entry 3

Bowden Christopher · CIK 0001608601 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 881

F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F4 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $78.00 to $78.21. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

Read SEC document
February 16, 2018 Filed Feb 20, 2018 21:03 UTC
Bowden ChristopherChief Medical Officer
SaleCommon stock 1,500 $77.51 $116,265.00
Disclosure

SEC source: 0001209191-18-011244 · doc4.xml · nonDerivative · entry 2

Bowden Christopher · CIK 0001608601 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,381

F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F3 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $76.98 to $77.91. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

Read SEC document
February 16, 2018 Filed Feb 20, 2018 21:03 UTC
Bowden ChristopherChief Medical Officer
Exercise / conversionCommon stock 2,000 $35.16 $70,320.00
Disclosure

SEC source: 0001209191-18-011244 · doc4.xml · nonDerivative · entry 1

Bowden Christopher · CIK 0001608601 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,881

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document
February 16, 2018 Filed Feb 20, 2018 21:02 UTC
Biller ScottChief Scientific Officer
GrantRestricted stock units · Derivative 8,250 $0.00 $0.00
Disclosure

SEC source: 0001209191-18-011242 · doc4.xml · derivative · entry 2

Biller Scott · CIK 0001581956 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,250

Underlying: Common stock · 8,250 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock.

F3 · derivative.exercise_date: The restricted stock units were granted on February 16, 2018. The shares underlying the restricted stock units will vest in three equal annual installments on February 16, 2019, 2020 and 2021. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

F3 · derivative.expiration_date: The restricted stock units were granted on February 16, 2018. The shares underlying the restricted stock units will vest in three equal annual installments on February 16, 2019, 2020 and 2021. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

Read SEC document
February 16, 2018 Filed Feb 20, 2018 21:02 UTC
Biller ScottChief Scientific Officer
GrantStock option (right to buy) · Derivative 33,000 $0.00 Strike: $77.70 $0.00
Disclosure

SEC source: 0001209191-18-011242 · doc4.xml · derivative · entry 1

Biller Scott · CIK 0001581956 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,000

Underlying: Common stock · 33,000 shares

Expires 2028-02-15

F1 · derivative.exercise_date: This option was granted on February 16, 2018. The shares underlying this option vest as to 25% of the underlying shares on February 16, 2019, with the remaining 75% vesting in 36 equal monthly installments thereafter.

Read SEC document
February 16, 2018 Filed Feb 20, 2018 21:01 UTC
Schenkein David PDirector · Chief Executive Officer
GrantRestricted stock units · Derivative 24,375 $0.00 $0.00
Disclosure

SEC source: 0001209191-18-011239 · doc4.xml · derivative · entry 2

Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,375

Underlying: Common stock · 24,375 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock.

F3 · derivative.exercise_date: The restricted stock units were granted on February 16, 2018. The shares underlying the restricted stock units will vest in three equal annual installments on February 16, 2019, 2020 and 2021. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

F3 · derivative.expiration_date: The restricted stock units were granted on February 16, 2018. The shares underlying the restricted stock units will vest in three equal annual installments on February 16, 2019, 2020 and 2021. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

Read SEC document
February 16, 2018 Filed Feb 20, 2018 21:01 UTC
Schenkein David PDirector · Chief Executive Officer
GrantStock option (right to buy) · Derivative 97,500 $0.00 Strike: $77.70 $0.00
Disclosure

SEC source: 0001209191-18-011239 · doc4.xml · derivative · entry 1

Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 97,500

Underlying: Common stock · 97,500 shares

Expires 2028-02-15

F1 · derivative.exercise_date: This option was granted on February 16, 2018. The shares underlying this option vest as to 25% of the underlying shares on February 16, 2019, with the remaining 75% vesting in 36 equal monthly installments thereafter.

Read SEC document
February 05, 2018 Filed Feb 7, 2018 21:05 UTC
Biller ScottChief Scientific Officer
Exercise / conversionStock options (right to buy) · Derivative 2,936 $0.00 Strike: $9.05 $0.00
Disclosure

SEC source: 0001209191-18-008108 · doc4.xml · derivative · entry 8

Biller Scott · CIK 0001581956 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,154

Underlying: Common stock · 2,936 shares

Expires 2023-04-30

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F8 · derivative.exercise_date: This option was originally granted on April 30, 2013 for the purchase of 68,181 shares of common stock. The option vests as to 50% of the underlying shares upon the achievement of a performance milestone, and as to the remaining 50% of upon the achievement of a second performance milestone. The Company's board of directors determined that the first performance milestone was achieved on December 3, 2015, resulting in the vesting of this option as to 34,091 shares. On January 26, 2017, the Company's board of directors determined that the second performance milestone was achieved, resulting in the vesting of this option as to the remaining 34,090 shares.

Read SEC document
February 05, 2018 Filed Feb 7, 2018 21:05 UTC
Biller ScottChief Scientific Officer
Exercise / conversionStock options (right to buy) · Derivative 64 $0.00 Strike: $0.47 $0.00
Disclosure

SEC source: 0001209191-18-008108 · doc4.xml · derivative · entry 7

Biller Scott · CIK 0001581956 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,803

Underlying: Common stock · 64 shares

Expires 2020-12-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F7 · derivative.exercise_date: This option was granted on December 7, 2010. The shares underlying this option vested as to 25% of the shares upon the achievement of a performance milestone, and as to the remaining 75% in 36 equal monthly installments thereafter. The performance criteria was met on June 23, 2015.

Read SEC document
February 05, 2018 Filed Feb 7, 2018 21:05 UTC
Biller ScottChief Scientific Officer
SaleCommon stock 400 $78.03 $31,212.00
Disclosure

SEC source: 0001209191-18-008108 · doc4.xml · nonDerivative · entry 6

Biller Scott · CIK 0001581956 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 53,059

F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F6 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $77.63 to $78.45. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

Read SEC document
February 05, 2018 Filed Feb 7, 2018 21:05 UTC
Biller ScottChief Scientific Officer
SaleCommon stock 701 $76.76 $53,808.76
Disclosure

SEC source: 0001209191-18-008108 · doc4.xml · nonDerivative · entry 5

Biller Scott · CIK 0001581956 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 53,459

F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F5 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $76.44 to $77.20. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

Read SEC document
February 05, 2018 Filed Feb 7, 2018 21:05 UTC
Biller ScottChief Scientific Officer
SaleCommon stock 1,100 $75.70 $83,270.00
Disclosure

SEC source: 0001209191-18-008108 · doc4.xml · nonDerivative · entry 4

Biller Scott · CIK 0001581956 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 54,160

F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F4 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $75.31 to $76.26. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

Read SEC document
February 05, 2018 Filed Feb 7, 2018 21:05 UTC
Biller ScottChief Scientific Officer
SaleCommon stock 799 $74.89 $59,837.11
Disclosure

SEC source: 0001209191-18-008108 · doc4.xml · nonDerivative · entry 3

Biller Scott · CIK 0001581956 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 55,260

F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F3 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $74.16 to $75.06. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

Read SEC document
February 05, 2018 Filed Feb 7, 2018 21:05 UTC
Biller ScottChief Scientific Officer
Exercise / conversionCommon stock 2,936 $9.05 $26,570.80
Disclosure

SEC source: 0001209191-18-008108 · doc4.xml · nonDerivative · entry 2

Biller Scott · CIK 0001581956 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 56,059

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document
February 05, 2018 Filed Feb 7, 2018 21:05 UTC
Biller ScottChief Scientific Officer
Exercise / conversionCommon stock 64 $0.47 $29.92
Disclosure

SEC source: 0001209191-18-008108 · doc4.xml · nonDerivative · entry 1

Biller Scott · CIK 0001581956 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 53,123

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document
February 01, 2018 Filed Feb 5, 2018 21:43 UTC
Bowden ChristopherChief Medical Officer
Exercise / conversionStock option (right to buy) · Derivative 2,000 $0.00 Strike: $35.16 $0.00
Disclosure

SEC source: 0001209191-18-007532 · doc4.xml · derivative · entry 4

Bowden Christopher · CIK 0001608601 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 107,000

Underlying: Common stock · 2,000 shares

Expires 2024-05-30

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F5 · derivative.exercise_date: This option was granted on May 31, 2014. The shares underlying this option vest as to 25% of the underlying shares on May 13, 2015, with the remaining 75% vesting in 36 equal monthly installments thereafter.

Read SEC document
February 01, 2018 Filed Feb 5, 2018 21:43 UTC
Bowden ChristopherChief Medical Officer
SaleCommon stock 685 $79.23 $54,272.55
Disclosure

SEC source: 0001209191-18-007532 · doc4.xml · nonDerivative · entry 3

Bowden Christopher · CIK 0001608601 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 881

F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F4 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $79.03 to $79.72. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

Read SEC document
February 01, 2018 Filed Feb 5, 2018 21:43 UTC
Bowden ChristopherChief Medical Officer
SaleCommon stock 1,315 $78.50 $103,227.50
Disclosure

SEC source: 0001209191-18-007532 · doc4.xml · nonDerivative · entry 2

Bowden Christopher · CIK 0001608601 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,566

F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F3 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $78.01 to $79.00. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

Read SEC document
February 01, 2018 Filed Feb 5, 2018 21:43 UTC
Bowden ChristopherChief Medical Officer
Exercise / conversionCommon stock 2,000 $35.16 $70,320.00
Disclosure

SEC source: 0001209191-18-007532 · doc4.xml · nonDerivative · entry 1

Bowden Christopher · CIK 0001608601 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,881

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document
February 01, 2018 Filed Feb 5, 2018 21:40 UTC
Schenkein David PDirector · Chief Executive Officer
Exercise / conversionStock option (right to buy) · Derivative 13,000 $0.00 Strike: $0.30 $0.00
Disclosure

SEC source: 0001209191-18-007529 · doc4.xml · derivative · entry 6

Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 104,567

Underlying: Common stock · 13,000 shares

Expires 2019-08-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F7 · derivative.exercise_date: This option was granted on August 13, 2009. The option vested as to 50% of the underlying shares upon the achievement of a performance milestone, as determined by the issuer's Board of Directors on June 3, 2010, and as to the remaining 50% of the underlying shares in equal monthly installments through June 3, 2013.

Read SEC document
February 01, 2018 Filed Feb 5, 2018 21:40 UTC
Schenkein David PDirector · Chief Executive Officer
SaleCommon stock 4,460 $79.23 $353,365.80
Disclosure

SEC source: 0001209191-18-007529 · doc4.xml · nonDerivative · entry 3

Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F4 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $79.03 to $79.72. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

Read SEC document
February 01, 2018 Filed Feb 5, 2018 21:40 UTC
Schenkein David PDirector · Chief Executive Officer
SaleCommon stock 8,540 $78.50 $670,390.00
Disclosure

SEC source: 0001209191-18-007529 · doc4.xml · nonDerivative · entry 2

Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,460

F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F3 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $78.01 to $79.00. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

Read SEC document
February 01, 2018 Filed Feb 5, 2018 21:40 UTC
Schenkein David PDirector · Chief Executive Officer
Exercise / conversionCommon stock 13,000 $0.30 $3,932.50
Disclosure

SEC source: 0001209191-18-007529 · doc4.xml · nonDerivative · entry 1

Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document
January 26, 2018 Filed Jan 30, 2018 21:26 UTC
Schenkein David PDirector · Chief Executive Officer
Exercise / conversionStock option (right to buy) · Derivative 23,572 $0.00 Strike: $0.30 $0.00
Disclosure

SEC source: 0001209191-18-006004 · doc4.xml · derivative · entry 7

Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 117,567

Underlying: Common stock · 23,572 shares

Expires 2019-08-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F8 · derivative.exercise_date: This option was granted on August 13, 2009. The option vested as to 50% of the underlying shares upon the achievement of a performance milestone, as determined by the issuer's Board of Directors on June 3, 2010, and as to the remaining 50% of the underlying shares in equal monthly installments through June 3, 2013.

Read SEC document
January 26, 2018 Filed Jan 30, 2018 21:26 UTC
Schenkein David PDirector · Chief Executive Officer
SaleCommon stock 2,966 $82.22 $243,864.52
Disclosure

SEC source: 0001209191-18-006004 · doc4.xml · nonDerivative · entry 4

Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F5 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $82.00 to $82.62. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

Read SEC document
January 26, 2018 Filed Jan 30, 2018 21:26 UTC
Schenkein David PDirector · Chief Executive Officer
SaleCommon stock 11,369 $81.40 $925,436.60
Disclosure

SEC source: 0001209191-18-006004 · doc4.xml · nonDerivative · entry 3

Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,966

F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F4 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $81.00 to $81.95. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

Read SEC document
January 26, 2018 Filed Jan 30, 2018 21:26 UTC
Schenkein David PDirector · Chief Executive Officer
SaleCommon stock 9,237 $80.35 $742,192.95
Disclosure

SEC source: 0001209191-18-006004 · doc4.xml · nonDerivative · entry 2

Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,335

F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F3 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $80.00 to $80.96. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

Read SEC document
January 26, 2018 Filed Jan 30, 2018 21:26 UTC
Schenkein David PDirector · Chief Executive Officer
Exercise / conversionCommon stock 23,572 $0.30 $7,130.53
Disclosure

SEC source: 0001209191-18-006004 · doc4.xml · nonDerivative · entry 1

Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,572

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document
January 24, 2018 Filed Jan 25, 2018 21:03 UTC
Schenkein David PDirector · Chief Executive Officer
Exercise / conversionStock option (right to buy) · Derivative 13,533 $0.00 Strike: $0.30 $0.00
Disclosure

SEC source: 0001209191-18-005357 · doc4.xml · derivative · entry 8

Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 141,159

Underlying: Common stock · 13,533 shares

Expires 2019-08-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F8 · derivative.exercise_date: This option was granted on August 13, 2009. The option vested as to 50% of the underlying shares upon the achievement of a performance milestone, as determined by the issuer's Board of Directors on June 3, 2010, and as to the remaining 50% of the underlying shares in equal monthly installments through June 3, 2013.

Read SEC document
January 24, 2018 Filed Jan 25, 2018 21:03 UTC
Schenkein David PDirector · Chief Executive Officer
SaleCommon stock 13,533 $80.01 $1,082,775.33
Disclosure

SEC source: 0001209191-18-005357 · doc4.xml · nonDerivative · entry 4

Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F4 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $80.00 to $80.07. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

Read SEC document
January 24, 2018 Filed Jan 25, 2018 21:03 UTC
Schenkein David PDirector · Chief Executive Officer
Exercise / conversionCommon stock 13,533 $0.30 $4,093.73
Disclosure

SEC source: 0001209191-18-005357 · doc4.xml · nonDerivative · entry 3

Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,533

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document
January 24, 2018 Filed Jan 26, 2018 21:22 UTC
Schenkein David PDirector · Chief Executive Officer
Exercise / conversionStock option (right to buy) · Derivative 20 $0.00 Strike: $0.30 $0.00
Disclosure

SEC source: 0001209191-18-005584 · doc4.xml · derivative · entry 5

Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 141,139

Underlying: Common stock · 20 shares

Expires 2019-08-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F6 · derivative.exercise_date: This option was granted on August 13, 2009. The option vested as to 50% of the underlying shares upon the achievement of a performance milestone, as determined by the issuer's Board of Directors on June 3, 2010, and as to the remaining 50% of the underlying shares in equal monthly installments through June 3, 2013.

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January 24, 2018 Filed Jan 26, 2018 21:22 UTC
Schenkein David PDirector · Chief Executive Officer
SaleCommon stock 20 $80.01 $1,600.20
Disclosure

SEC source: 0001209191-18-005584 · doc4.xml · nonDerivative · entry 2

Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F3 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $80.00 to $80.07. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

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January 24, 2018 Filed Jan 26, 2018 21:22 UTC
Schenkein David PDirector · Chief Executive Officer
Exercise / conversionCommon stock 20 $0.30 $6.05
Disclosure

SEC source: 0001209191-18-005584 · doc4.xml · nonDerivative · entry 1

Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document
January 23, 2018 Filed Jan 23, 2018 16:35 UTC PurchaseCommon Stock 851,154 $67.00 $57,027,318.00
Disclosure

SEC source: 0001209191-18-004895 · doc4.xml · nonDerivative · entry 1

CELGENE CORP /DE/ · CIK 0000816284 · 10% owner

Celgene Switzerland LLC · CIK 0001661486 · 10% owner

Celgene Alpine Investment Co., LLC · CIK 0001581774 · 10% owner

Celgene European Investment Co LLC · CIK 0001577650 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,374,599

Read SEC document
January 23, 2018 Filed Jan 25, 2018 22:16 UTC Amendment
Hoerter Steven L.Chief Commercial Officer
Exercise / conversionStock option (right to buy) · Derivative 25,000 $0.00 Strike: $39.76 $0.00
Disclosure

SEC source: 0001209191-18-005432 · doc4a.xml · derivative · entry 1

Hoerter Steven L. · CIK 0001533451 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 75,000

Underlying: Common stock · 25,000 shares

Expires 2016-02-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · shares: The original Form 4, filed on January 25, 2018, stated that 25,000 derivative securities were acquired as a result of the transaction, when in fact the transaction was a disposition of 25,000 derivative securities. This Form 4 amendment is to solely to correct the nature of the transaction.

F3 · derivative.exercise_date: This option was granted on February 16, 2016. The shares underlying this option vest as to 25% of the underlying shares on February 16, 2017, with the remaining 75% vesting in 36 equal monthly installments thereafter.

Read SEC document
January 23, 2018 Filed Jan 25, 2018 21:03 UTC
Hoerter Steven L.Chief Commercial Officer
Exercise / conversionStock option (right to buy) · Derivative 25,000 $0.00 Strike: $39.76 $0.00
Disclosure

SEC source: 0001209191-18-005360 · doc4.xml · derivative · entry 3

Hoerter Steven L. · CIK 0001533451 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 75,000

Underlying: Common stock · 25,000 shares

Expires 2026-02-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F3 · derivative.exercise_date: This option was granted on February 16, 2016. The shares underlying this option vest as to 25% of the underlying shares on February 16, 2017, with the remaining 75% vesting in 36 equal monthly installments thereafter.

Read SEC document
January 23, 2018 Filed Jan 25, 2018 21:03 UTC
Hoerter Steven L.Chief Commercial Officer
SaleCommon stock 25,000 $74.83 $1,870,750.00
Disclosure

SEC source: 0001209191-18-005360 · doc4.xml · nonDerivative · entry 2

Hoerter Steven L. · CIK 0001533451 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document
January 23, 2018 Filed Jan 25, 2018 21:03 UTC
Hoerter Steven L.Chief Commercial Officer
Exercise / conversionCommon stock 25,000 $39.76 $994,000.00
Disclosure

SEC source: 0001209191-18-005360 · doc4.xml · nonDerivative · entry 1

Hoerter Steven L. · CIK 0001533451 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document
January 23, 2018 Filed Jan 25, 2018 21:03 UTC
Schenkein David PDirector · Chief Executive Officer
Exercise / conversionStock option (right to buy) · Derivative 32,875 $0.00 Strike: $0.30 $0.00
Disclosure

SEC source: 0001209191-18-005357 · doc4.xml · derivative · entry 7

Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,962

Underlying: Common stock · 32,875 shares

Expires 2019-08-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F7 · derivative.exercise_date: This option was granted on August 13, 2009. The shares underlying this option vest as to 25% of the shares on August 1, 2010, with the remaining 75% vesting in 36 equal monthly installments thereafter.

Read SEC document
January 23, 2018 Filed Jan 25, 2018 21:03 UTC
Schenkein David PDirector · Chief Executive Officer
SaleCommon stock 32,875 $80.01 $2,630,328.75
Disclosure

SEC source: 0001209191-18-005357 · doc4.xml · nonDerivative · entry 2

Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F3 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $80.00 to $80.10. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

Read SEC document
January 23, 2018 Filed Jan 25, 2018 21:03 UTC
Schenkein David PDirector · Chief Executive Officer
Exercise / conversionCommon stock 32,875 $0.30 $9,944.69
Disclosure

SEC source: 0001209191-18-005357 · doc4.xml · nonDerivative · entry 1

Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,875

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document
January 23, 2018 Filed Jan 31, 2018 08:39 UTC Amendment PurchaseCommon Stock 851,154 $67.00 $57,027,318.00
Disclosure

SEC source: 0001209191-18-006131 · doc4a.xml · nonDerivative · entry 1

CELGENE CORP /DE/ · CIK 0000816284 · 10% owner

Celgene Switzerland LLC · CIK 0001661486 · 10% owner

Celgene Alpine Investment Co., LLC · CIK 0001581774 · 10% owner

Celgene European Investment Co LLC · CIK 0001577650 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,374,599

F1 · date: This Form 4 Amendment is being submitted to correct the date of earliest transaction in box 3 to reflect January 23, 2018.

Read SEC document
January 16, 2018 Filed Jan 16, 2018 22:16 UTC
Schenkein David PDirector · Chief Executive Officer
Exercise / conversionStock option (right to buy) · Derivative 53,000 $0.00 Strike: $0.30 $0.00
Disclosure

SEC source: 0001209191-18-003637 · doc4.xml · derivative · entry 8

Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 154,692

Underlying: Common stock · 53,000 shares

Expires 2019-08-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F9 · derivative.exercise_date: This option was granted on August 13, 2009. The option vested as to 50% of the underlying shares upon the achievement of a performance milestone, as determined by the issuer's Board of Directors on June 3, 2010, and as to the remaining 50% of the underlying shares in equal monthly installments through June 3, 2013.

Read SEC document
January 16, 2018 Filed Jan 16, 2018 22:16 UTC
Schenkein David PDirector · Chief Executive Officer
SaleCommon stock 6,597 $74.80 $493,455.60
Disclosure

SEC source: 0001209191-18-003637 · doc4.xml · nonDerivative · entry 5

Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F6 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $74.56 to $75.07. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

Read SEC document
January 16, 2018 Filed Jan 16, 2018 22:16 UTC
Schenkein David PDirector · Chief Executive Officer
SaleCommon stock 10,914 $74.11 $808,836.54
Disclosure

SEC source: 0001209191-18-003637 · doc4.xml · nonDerivative · entry 4

Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,597

F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F5 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $73.56 to $74.55. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

Read SEC document
January 16, 2018 Filed Jan 16, 2018 22:16 UTC
Schenkein David PDirector · Chief Executive Officer
SaleCommon stock 22,304 $73.02 $1,628,638.08
Disclosure

SEC source: 0001209191-18-003637 · doc4.xml · nonDerivative · entry 3

Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,511

F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F4 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $72.56 to $73.55. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

Read SEC document
January 16, 2018 Filed Jan 16, 2018 22:16 UTC
Schenkein David PDirector · Chief Executive Officer
SaleCommon stock 13,185 $71.77 $946,287.45
Disclosure

SEC source: 0001209191-18-003637 · doc4.xml · nonDerivative · entry 2

Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,815

F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F3 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $71.50 to $72.42. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

Read SEC document
January 16, 2018 Filed Jan 16, 2018 22:16 UTC
Schenkein David PDirector · Chief Executive Officer
Exercise / conversionCommon stock 53,000 $0.30 $16,032.50
Disclosure

SEC source: 0001209191-18-003637 · doc4.xml · nonDerivative · entry 1

Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 53,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.