ABSI

SEC source: 0001628280-21-014732 · wf-form4_162750420600927.xml · nonDerivative · entry 4

Casdin Partners Master Fund, L.P. · CIK 0001534265 · Director

Casdin Capital, LLC · CIK 0001534261 · Director

Casdin Partners GP, LLC · CIK 0001534260 · Director

Casdin Private Growth Equity Fund, L.P. · CIK 0001823061 · Director

CASDIN PRIVATE GROWTH EQUITY FUND GP, LLC · CIK 0001864554 · Director

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 973,260

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · price: This convertible promissory note ("Convertible Note") had a maturity date of September 16, 2023. The principal and accrued interest under the Convertible Note converted upon the closing of the IPO into shares of Common Stock at a conversion price equal to $13.12 per share without payment of additional consideration.

F4 · ownership.nature: These shares are held by Casdin Private Growth Equity Fund, L.P. Casdin Capital is the investment adviser to Casdin Private Growth Equity Fund, L.P. and Casdin Private Growth Equity Fund GP, LLC ("Casdin Private Growth GP") is the general partner of Casdin Private Growth Equity Fund, L.P. Eli Casdin is the managing member of Casdin Capital and Casdin Private Growth GP. Each of Casdin Capital, Casdin Private Growth GP and Eli Casdin disclaims beneficial ownership of such securities except to the extent of their respective pecuniary interest therein, if any. Eli Casdin is a director of the Issuer and, accordingly, files separate Section 16 reports.

SEC source: 0001628280-21-014732 · wf-form4_162750420600927.xml · nonDerivative · entry 3

Casdin Partners Master Fund, L.P. · CIK 0001534265 · Director

Casdin Capital, LLC · CIK 0001534261 · Director

Casdin Partners GP, LLC · CIK 0001534260 · Director

Casdin Private Growth Equity Fund, L.P. · CIK 0001823061 · Director

CASDIN PRIVATE GROWTH EQUITY FUND GP, LLC · CIK 0001864554 · Director

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,745,333

F2 · ownership.direct: These shares are held by Casdin Partners Master Fund, L.P. Casdin Capital, LLC ("Casdin Capital") is the investment adviser to Casdin Partners Master Fund, L.P., and Casdin Partners GP, LLC ("Casdin Partners GP") is the general partner of Casdin Partners Master Fund, L.P. Eli Casdin is the managing member of Casdin Capital and Casdin Partners GP. Each of Casdin Capital, Casdin Partners GP and Eli Casdin disclaims beneficial ownership of such securities except to the extent of their respective pecuniary interest therein, if any. Eli Casdin is a director of the Issuer and, accordingly, files separate Section 16 reports

SEC source: 0001628280-21-014732 · wf-form4_162750420600927.xml · nonDerivative · entry 2

Casdin Partners Master Fund, L.P. · CIK 0001534265 · Director

Casdin Capital, LLC · CIK 0001534261 · Director

Casdin Partners GP, LLC · CIK 0001534260 · Director

Casdin Private Growth Equity Fund, L.P. · CIK 0001823061 · Director

CASDIN PRIVATE GROWTH EQUITY FUND GP, LLC · CIK 0001864554 · Director

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,182,833

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · price: This convertible promissory note ("Convertible Note") had a maturity date of September 16, 2023. The principal and accrued interest under the Convertible Note converted upon the closing of the IPO into shares of Common Stock at a conversion price equal to $13.12 per share without payment of additional consideration.

F2 · ownership.direct: These shares are held by Casdin Partners Master Fund, L.P. Casdin Capital, LLC ("Casdin Capital") is the investment adviser to Casdin Partners Master Fund, L.P., and Casdin Partners GP, LLC ("Casdin Partners GP") is the general partner of Casdin Partners Master Fund, L.P. Eli Casdin is the managing member of Casdin Capital and Casdin Partners GP. Each of Casdin Capital, Casdin Partners GP and Eli Casdin disclaims beneficial ownership of such securities except to the extent of their respective pecuniary interest therein, if any. Eli Casdin is a director of the Issuer and, accordingly, files separate Section 16 reports

SEC source: 0001628280-21-014732 · wf-form4_162750420600927.xml · nonDerivative · entry 1

Casdin Partners Master Fund, L.P. · CIK 0001534265 · Director

Casdin Capital, LLC · CIK 0001534261 · Director

Casdin Partners GP, LLC · CIK 0001534260 · Director

Casdin Private Growth Equity Fund, L.P. · CIK 0001823061 · Director

CASDIN PRIVATE GROWTH EQUITY FUND GP, LLC · CIK 0001864554 · Director

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,209,573

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: These shares of the Series E Preferred Stock automatically converted on a one-for-3.3031 basis into the number of shares of the Issuer's common stock, par value $0.0001 per share ("Common Stock"), shown in Column 7 immediately upon closing of the Issuer's initial public offering ("IPO") without payment of additional consideration. The Series E Preferred Stock had no expiration date.

F2 · ownership.direct: These shares are held by Casdin Partners Master Fund, L.P. Casdin Capital, LLC ("Casdin Capital") is the investment adviser to Casdin Partners Master Fund, L.P., and Casdin Partners GP, LLC ("Casdin Partners GP") is the general partner of Casdin Partners Master Fund, L.P. Eli Casdin is the managing member of Casdin Capital and Casdin Partners GP. Each of Casdin Capital, Casdin Partners GP and Eli Casdin disclaims beneficial ownership of such securities except to the extent of their respective pecuniary interest therein, if any. Eli Casdin is a director of the Issuer and, accordingly, files separate Section 16 reports

SEC source: 0001104659-21-097155 · tm2123458-1_4seq1.xml · derivative · entry 5

Redmile Group, LLC · CIK 0001425738 · Director

Green Jeremy · CIK 0001650527 · Director

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 0

Underlying: Common Stock · 1,946,521 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: The convertible promissory note dated March 17, 2021 automatically converted into shares of the Issuer's common stock upon the closing of the Issuer's initial public offering based on a conversion price equal to $13.12 per share, which was the purchase price per share (after the forward stock split noted above) paid by investors in connection with the closing of the Issuer's initial public offering, less a discount equal to 18% of such purchase price.

F2 · derivative.expiration_date: The convertible promissory note dated March 17, 2021 automatically converted into shares of the Issuer's common stock upon the closing of the Issuer's initial public offering based on a conversion price equal to $13.12 per share, which was the purchase price per share (after the forward stock split noted above) paid by investors in connection with the closing of the Issuer's initial public offering, less a discount equal to 18% of such purchase price.

F3 · ownership.nature: These securities are directly owned by private investment vehicles managed by Redmile Group, LLC ("Redmile") and may be deemed beneficially owned by Redmile as investment manager of such private investment vehicles. The reported securities may also be deemed beneficially owned by Jeremy Green as the principal of Redmile. Each of Redmile and Mr. Green (collectively, the "Reporting Persons") disclaims beneficial ownership of the reported securities except to the extent of their pecuniary interest therein. This report shall not be deemed an admission that such Reporting Persons are a beneficial owner of such securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

SEC source: 0001104659-21-097155 · tm2123458-1_4seq1.xml · derivative · entry 4

Redmile Group, LLC · CIK 0001425738 · Director

Green Jeremy · CIK 0001650527 · Director

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 0

Underlying: Common Stock · 4,209,573 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: The Series E convertible preferred stock automatically converted into shares of the Issuer's common stock upon the closing of the Issuer's initial public offering based on a pre-stock split conversion price of $19.6166 per share. On July 19, 2021, the Issuer effected a one-for-3.3031 forward stock split of its common stock. The Series E convertible preferred stock has no expiration date.

F1 · derivative.exercise_date: The Series E convertible preferred stock automatically converted into shares of the Issuer's common stock upon the closing of the Issuer's initial public offering based on a pre-stock split conversion price of $19.6166 per share. On July 19, 2021, the Issuer effected a one-for-3.3031 forward stock split of its common stock. The Series E convertible preferred stock has no expiration date.

F1 · derivative.expiration_date: The Series E convertible preferred stock automatically converted into shares of the Issuer's common stock upon the closing of the Issuer's initial public offering based on a pre-stock split conversion price of $19.6166 per share. On July 19, 2021, the Issuer effected a one-for-3.3031 forward stock split of its common stock. The Series E convertible preferred stock has no expiration date.

F3 · ownership.nature: These securities are directly owned by private investment vehicles managed by Redmile Group, LLC ("Redmile") and may be deemed beneficially owned by Redmile as investment manager of such private investment vehicles. The reported securities may also be deemed beneficially owned by Jeremy Green as the principal of Redmile. Each of Redmile and Mr. Green (collectively, the "Reporting Persons") disclaims beneficial ownership of the reported securities except to the extent of their pecuniary interest therein. This report shall not be deemed an admission that such Reporting Persons are a beneficial owner of such securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

SEC source: 0001104659-21-097155 · tm2123458-1_4seq1.xml · nonDerivative · entry 3

Redmile Group, LLC · CIK 0001425738 · Director

Green Jeremy · CIK 0001650527 · Director

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 8,031,094

F3 · ownership.nature: These securities are directly owned by private investment vehicles managed by Redmile Group, LLC ("Redmile") and may be deemed beneficially owned by Redmile as investment manager of such private investment vehicles. The reported securities may also be deemed beneficially owned by Jeremy Green as the principal of Redmile. Each of Redmile and Mr. Green (collectively, the "Reporting Persons") disclaims beneficial ownership of the reported securities except to the extent of their pecuniary interest therein. This report shall not be deemed an admission that such Reporting Persons are a beneficial owner of such securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

SEC source: 0001104659-21-097155 · tm2123458-1_4seq1.xml · nonDerivative · entry 2

Redmile Group, LLC · CIK 0001425738 · Director

Green Jeremy · CIK 0001650527 · Director

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 6,156,094

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · shares: The convertible promissory note dated March 17, 2021 automatically converted into shares of the Issuer's common stock upon the closing of the Issuer's initial public offering based on a conversion price equal to $13.12 per share, which was the purchase price per share (after the forward stock split noted above) paid by investors in connection with the closing of the Issuer's initial public offering, less a discount equal to 18% of such purchase price.

F2 · price: The convertible promissory note dated March 17, 2021 automatically converted into shares of the Issuer's common stock upon the closing of the Issuer's initial public offering based on a conversion price equal to $13.12 per share, which was the purchase price per share (after the forward stock split noted above) paid by investors in connection with the closing of the Issuer's initial public offering, less a discount equal to 18% of such purchase price.

F3 · ownership.nature: These securities are directly owned by private investment vehicles managed by Redmile Group, LLC ("Redmile") and may be deemed beneficially owned by Redmile as investment manager of such private investment vehicles. The reported securities may also be deemed beneficially owned by Jeremy Green as the principal of Redmile. Each of Redmile and Mr. Green (collectively, the "Reporting Persons") disclaims beneficial ownership of the reported securities except to the extent of their pecuniary interest therein. This report shall not be deemed an admission that such Reporting Persons are a beneficial owner of such securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

SEC source: 0001104659-21-097155 · tm2123458-1_4seq1.xml · nonDerivative · entry 1

Redmile Group, LLC · CIK 0001425738 · Director

Green Jeremy · CIK 0001650527 · Director

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 4,209,573

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: The Series E convertible preferred stock automatically converted into shares of the Issuer's common stock upon the closing of the Issuer's initial public offering based on a pre-stock split conversion price of $19.6166 per share. On July 19, 2021, the Issuer effected a one-for-3.3031 forward stock split of its common stock. The Series E convertible preferred stock has no expiration date.

F1 · price: The Series E convertible preferred stock automatically converted into shares of the Issuer's common stock upon the closing of the Issuer's initial public offering based on a pre-stock split conversion price of $19.6166 per share. On July 19, 2021, the Issuer effected a one-for-3.3031 forward stock split of its common stock. The Series E convertible preferred stock has no expiration date.

F3 · ownership.nature: These securities are directly owned by private investment vehicles managed by Redmile Group, LLC ("Redmile") and may be deemed beneficially owned by Redmile as investment manager of such private investment vehicles. The reported securities may also be deemed beneficially owned by Jeremy Green as the principal of Redmile. Each of Redmile and Mr. Green (collectively, the "Reporting Persons") disclaims beneficial ownership of the reported securities except to the extent of their pecuniary interest therein. This report shall not be deemed an admission that such Reporting Persons are a beneficial owner of such securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

SEC source: 0001628280-21-014739 · wf-form4_162750454185736.xml · nonDerivative · entry 1

MCGINNIS KAREN K · CIK 0001188264 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

SEC source: 0001628280-21-014738 · wf-form4_162750451364117.xml · nonDerivative · entry 1

McClain Sean · CIK 0001873003 · Director · President and Chief Executive · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,361,800

SEC source: 0001628280-21-014731 · wf-form4_162750417875070.xml · derivative · entry 7

Casdin Eli · CIK 0001534264 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 0

Underlying: Common Stock · 973,260 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: This convertible promissory note ("Convertible Note") had a maturity date of September 16, 2023. The principal and accrued interest under the Convertible Note converted upon the closing of the IPO into shares of Common Stock at a conversion price equal to $13.12 per share without payment of additional consideration.

F3 · derivative.expiration_date: This convertible promissory note ("Convertible Note") had a maturity date of September 16, 2023. The principal and accrued interest under the Convertible Note converted upon the closing of the IPO into shares of Common Stock at a conversion price equal to $13.12 per share without payment of additional consideration.

F4 · ownership.nature: These shares are held by Casdin Private Growth Equity Fund, L.P. Casdin Capital is the investment adviser to Casdin Private Growth Equity Fund, L.P. and Casdin Private Growth Equity Fund GP, LLC ("Casdin Private Growth GP") is the general partner of Casdin Private Growth Equity Fund, L.P. Eli Casdin is the managing member of Casdin Capital and Casdin Private Growth GP. Each of Casdin Capital, Casdin Private Growth GP and Eli Casdin disclaims beneficial ownership of such securities except to the extent of their respective pecuniary interest therein, if any.

SEC source: 0001628280-21-014731 · wf-form4_162750417875070.xml · derivative · entry 6

Casdin Eli · CIK 0001534264 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 0

Underlying: Common Stock · 973,260 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: This convertible promissory note ("Convertible Note") had a maturity date of September 16, 2023. The principal and accrued interest under the Convertible Note converted upon the closing of the IPO into shares of Common Stock at a conversion price equal to $13.12 per share without payment of additional consideration.

F3 · derivative.expiration_date: This convertible promissory note ("Convertible Note") had a maturity date of September 16, 2023. The principal and accrued interest under the Convertible Note converted upon the closing of the IPO into shares of Common Stock at a conversion price equal to $13.12 per share without payment of additional consideration.

F2 · ownership.nature: These shares are held by Casdin Partners Master Fund, L.P. Casdin Capital, LLC ("Casdin Capital") is the investment adviser to Casdin Partners Master Fund, L.P., and Casdin Partners GP, LLC ("Casdin Partners GP") is the general partner of Casdin Partners Master Fund, L.P. Eli Casdin is the managing member of Casdin Capital and Casdin Partners GP. Each of Casdin Capital, Casdin Partners GP and Eli Casdin disclaims beneficial ownership of such securities except to the extent of their respective pecuniary interest therein, if any.

SEC source: 0001628280-21-014731 · wf-form4_162750417875070.xml · derivative · entry 5

Casdin Eli · CIK 0001534264 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 0

Underlying: Common Stock · 4,209,573 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: These shares of the Series E Preferred Stock automatically converted on a one-for-3.3031 basis into the number of shares of the Issuer's common stock, par value $0.0001 per share ("Common Stock"), shown in Column 7 immediately upon closing of the Issuer's initial public offering ("IPO") without payment of additional consideration. The Series E Preferred Stock had no expiration date.

F1 · derivative.exercise_date: These shares of the Series E Preferred Stock automatically converted on a one-for-3.3031 basis into the number of shares of the Issuer's common stock, par value $0.0001 per share ("Common Stock"), shown in Column 7 immediately upon closing of the Issuer's initial public offering ("IPO") without payment of additional consideration. The Series E Preferred Stock had no expiration date.

F1 · derivative.expiration_date: These shares of the Series E Preferred Stock automatically converted on a one-for-3.3031 basis into the number of shares of the Issuer's common stock, par value $0.0001 per share ("Common Stock"), shown in Column 7 immediately upon closing of the Issuer's initial public offering ("IPO") without payment of additional consideration. The Series E Preferred Stock had no expiration date.

F2 · ownership.nature: These shares are held by Casdin Partners Master Fund, L.P. Casdin Capital, LLC ("Casdin Capital") is the investment adviser to Casdin Partners Master Fund, L.P., and Casdin Partners GP, LLC ("Casdin Partners GP") is the general partner of Casdin Partners Master Fund, L.P. Eli Casdin is the managing member of Casdin Capital and Casdin Partners GP. Each of Casdin Capital, Casdin Partners GP and Eli Casdin disclaims beneficial ownership of such securities except to the extent of their respective pecuniary interest therein, if any.

SEC source: 0001628280-21-014731 · wf-form4_162750417875070.xml · nonDerivative · entry 4

Casdin Eli · CIK 0001534264 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 973,260

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · price: This convertible promissory note ("Convertible Note") had a maturity date of September 16, 2023. The principal and accrued interest under the Convertible Note converted upon the closing of the IPO into shares of Common Stock at a conversion price equal to $13.12 per share without payment of additional consideration.

F4 · ownership.nature: These shares are held by Casdin Private Growth Equity Fund, L.P. Casdin Capital is the investment adviser to Casdin Private Growth Equity Fund, L.P. and Casdin Private Growth Equity Fund GP, LLC ("Casdin Private Growth GP") is the general partner of Casdin Private Growth Equity Fund, L.P. Eli Casdin is the managing member of Casdin Capital and Casdin Private Growth GP. Each of Casdin Capital, Casdin Private Growth GP and Eli Casdin disclaims beneficial ownership of such securities except to the extent of their respective pecuniary interest therein, if any.

SEC source: 0001628280-21-014731 · wf-form4_162750417875070.xml · nonDerivative · entry 3

Casdin Eli · CIK 0001534264 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 6,745,333

F2 · ownership.nature: These shares are held by Casdin Partners Master Fund, L.P. Casdin Capital, LLC ("Casdin Capital") is the investment adviser to Casdin Partners Master Fund, L.P., and Casdin Partners GP, LLC ("Casdin Partners GP") is the general partner of Casdin Partners Master Fund, L.P. Eli Casdin is the managing member of Casdin Capital and Casdin Partners GP. Each of Casdin Capital, Casdin Partners GP and Eli Casdin disclaims beneficial ownership of such securities except to the extent of their respective pecuniary interest therein, if any.

SEC source: 0001628280-21-014731 · wf-form4_162750417875070.xml · nonDerivative · entry 2

Casdin Eli · CIK 0001534264 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 5,182,833

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · price: This convertible promissory note ("Convertible Note") had a maturity date of September 16, 2023. The principal and accrued interest under the Convertible Note converted upon the closing of the IPO into shares of Common Stock at a conversion price equal to $13.12 per share without payment of additional consideration.

F2 · ownership.nature: These shares are held by Casdin Partners Master Fund, L.P. Casdin Capital, LLC ("Casdin Capital") is the investment adviser to Casdin Partners Master Fund, L.P., and Casdin Partners GP, LLC ("Casdin Partners GP") is the general partner of Casdin Partners Master Fund, L.P. Eli Casdin is the managing member of Casdin Capital and Casdin Partners GP. Each of Casdin Capital, Casdin Partners GP and Eli Casdin disclaims beneficial ownership of such securities except to the extent of their respective pecuniary interest therein, if any.

SEC source: 0001628280-21-014731 · wf-form4_162750417875070.xml · nonDerivative · entry 1

Casdin Eli · CIK 0001534264 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 4,209,573

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: These shares of the Series E Preferred Stock automatically converted on a one-for-3.3031 basis into the number of shares of the Issuer's common stock, par value $0.0001 per share ("Common Stock"), shown in Column 7 immediately upon closing of the Issuer's initial public offering ("IPO") without payment of additional consideration. The Series E Preferred Stock had no expiration date.

F2 · ownership.nature: These shares are held by Casdin Partners Master Fund, L.P. Casdin Capital, LLC ("Casdin Capital") is the investment adviser to Casdin Partners Master Fund, L.P., and Casdin Partners GP, LLC ("Casdin Partners GP") is the general partner of Casdin Partners Master Fund, L.P. Eli Casdin is the managing member of Casdin Capital and Casdin Partners GP. Each of Casdin Capital, Casdin Partners GP and Eli Casdin disclaims beneficial ownership of such securities except to the extent of their respective pecuniary interest therein, if any.

SEC source: 0000899243-21-030340 · doc4.xml · derivative · entry 18

Phoenix Venture Partners II LP · CIK 0001647900 · 10% owner

Phoenix General Partner II LLC · CIK 0001874106 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 307,211 shares

Expires 2026-09-29

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F12 · derivative.exercise_date: The warrant for 93,007 shares of Series A-4 Preferred Stock converted into a warrant for 307,211 shares of Common Stock upon the one-for-3.3031 reverse split.

F12 · derivative.underlying_shares: The warrant for 93,007 shares of Series A-4 Preferred Stock converted into a warrant for 307,211 shares of Common Stock upon the one-for-3.3031 reverse split.

F3 · ownership.direct: Phoenix General Partner II LLC, as the sole general partner of Phoenix Venture Partners II LP, beneficially owns the reported securities indirectly, but disclaims beneficial ownership of the reported securities except to the extent of its pecuniary interest therein.

SEC source: 0000899243-21-030340 · doc4.xml · derivative · entry 17

Phoenix Venture Partners II LP · CIK 0001647900 · 10% owner

Phoenix General Partner II LLC · CIK 0001874106 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Series A-4 Preferred Stock · 93,007 shares

Expires 2026-09-29

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F11 · derivative.exercise_date: Prior to July 26, 2021, these warrants were exercisable by the holder at its option for shares of the Issuer's Series A-4 Preferred Stock at an exercise price of $1.00 per share any time prior to their expiration date.

F3 · ownership.direct: Phoenix General Partner II LLC, as the sole general partner of Phoenix Venture Partners II LP, beneficially owns the reported securities indirectly, but disclaims beneficial ownership of the reported securities except to the extent of its pecuniary interest therein.

SEC source: 0000899243-21-030340 · doc4.xml · derivative · entry 16

Phoenix Venture Partners II LP · CIK 0001647900 · 10% owner

Phoenix General Partner II LLC · CIK 0001874106 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 33,675 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F10 · derivative.exercise_price: The Series E Preferred Stock converted into Common Stock on a one-for-3.3031 basis and had no expiration date.

F10 · derivative.exercise_date: The Series E Preferred Stock converted into Common Stock on a one-for-3.3031 basis and had no expiration date.

F10 · derivative.expiration_date: The Series E Preferred Stock converted into Common Stock on a one-for-3.3031 basis and had no expiration date.

F2 · derivative.underlying_shares: Reflects one-for-3.3031 stock split which became effective on July 26, 2021.

F3 · ownership.direct: Phoenix General Partner II LLC, as the sole general partner of Phoenix Venture Partners II LP, beneficially owns the reported securities indirectly, but disclaims beneficial ownership of the reported securities except to the extent of its pecuniary interest therein.

SEC source: 0000899243-21-030340 · doc4.xml · derivative · entry 15

Phoenix Venture Partners II LP · CIK 0001647900 · 10% owner

Phoenix General Partner II LLC · CIK 0001874106 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 33,741 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F9 · derivative.exercise_price: The Series D-2 Preferred Stock converted into Common Stock on a one-for-3.3031 basis and had no expiration date.

F9 · derivative.exercise_date: The Series D-2 Preferred Stock converted into Common Stock on a one-for-3.3031 basis and had no expiration date.

F9 · derivative.expiration_date: The Series D-2 Preferred Stock converted into Common Stock on a one-for-3.3031 basis and had no expiration date.

F2 · derivative.underlying_shares: Reflects one-for-3.3031 stock split which became effective on July 26, 2021.

F3 · ownership.direct: Phoenix General Partner II LLC, as the sole general partner of Phoenix Venture Partners II LP, beneficially owns the reported securities indirectly, but disclaims beneficial ownership of the reported securities except to the extent of its pecuniary interest therein.

SEC source: 0000899243-21-030340 · doc4.xml · derivative · entry 14

Phoenix Venture Partners II LP · CIK 0001647900 · 10% owner

Phoenix General Partner II LLC · CIK 0001874106 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 84,348 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F8 · derivative.exercise_price: The Series D-1 Preferred Stock converted into Common Stock on a one-for-3.3031 basis and had no expiration date.

F8 · derivative.exercise_date: The Series D-1 Preferred Stock converted into Common Stock on a one-for-3.3031 basis and had no expiration date.

F8 · derivative.expiration_date: The Series D-1 Preferred Stock converted into Common Stock on a one-for-3.3031 basis and had no expiration date.

F2 · derivative.underlying_shares: Reflects one-for-3.3031 stock split which became effective on July 26, 2021.

F3 · ownership.direct: Phoenix General Partner II LLC, as the sole general partner of Phoenix Venture Partners II LP, beneficially owns the reported securities indirectly, but disclaims beneficial ownership of the reported securities except to the extent of its pecuniary interest therein.

SEC source: 0000899243-21-030340 · doc4.xml · derivative · entry 13

Phoenix Venture Partners II LP · CIK 0001647900 · 10% owner

Phoenix General Partner II LLC · CIK 0001874106 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 273,130 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_price: The Series C Preferred Stock converted into Common Stock on a one-for-3.3031 basis and had no expiration date.

F7 · derivative.exercise_date: The Series C Preferred Stock converted into Common Stock on a one-for-3.3031 basis and had no expiration date.

F7 · derivative.expiration_date: The Series C Preferred Stock converted into Common Stock on a one-for-3.3031 basis and had no expiration date.

F2 · derivative.underlying_shares: Reflects one-for-3.3031 stock split which became effective on July 26, 2021.

F3 · ownership.direct: Phoenix General Partner II LLC, as the sole general partner of Phoenix Venture Partners II LP, beneficially owns the reported securities indirectly, but disclaims beneficial ownership of the reported securities except to the extent of its pecuniary interest therein.

SEC source: 0000899243-21-030340 · doc4.xml · derivative · entry 12

Phoenix Venture Partners II LP · CIK 0001647900 · 10% owner

Phoenix General Partner II LLC · CIK 0001874106 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 2,590,991 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_price: The Series B Preferred Stock converted into Common Stock on a one-for-3.3031 basis and had no expiration date.

F6 · derivative.exercise_date: The Series B Preferred Stock converted into Common Stock on a one-for-3.3031 basis and had no expiration date.

F6 · derivative.expiration_date: The Series B Preferred Stock converted into Common Stock on a one-for-3.3031 basis and had no expiration date.

F2 · derivative.underlying_shares: Reflects one-for-3.3031 stock split which became effective on July 26, 2021.

F3 · ownership.direct: Phoenix General Partner II LLC, as the sole general partner of Phoenix Venture Partners II LP, beneficially owns the reported securities indirectly, but disclaims beneficial ownership of the reported securities except to the extent of its pecuniary interest therein.

SEC source: 0000899243-21-030340 · doc4.xml · derivative · entry 11

Phoenix Venture Partners II LP · CIK 0001647900 · 10% owner

Phoenix General Partner II LLC · CIK 0001874106 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 4,954,650 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_price: The Series A-3 Preferred Stock converted into Common Stock on a one-for-3.3031 basis and had no expiration date.

F5 · derivative.exercise_date: The Series A-3 Preferred Stock converted into Common Stock on a one-for-3.3031 basis and had no expiration date.

F5 · derivative.expiration_date: The Series A-3 Preferred Stock converted into Common Stock on a one-for-3.3031 basis and had no expiration date.

F2 · derivative.underlying_shares: Reflects one-for-3.3031 stock split which became effective on July 26, 2021.

F3 · ownership.direct: Phoenix General Partner II LLC, as the sole general partner of Phoenix Venture Partners II LP, beneficially owns the reported securities indirectly, but disclaims beneficial ownership of the reported securities except to the extent of its pecuniary interest therein.

SEC source: 0000899243-21-030340 · doc4.xml · derivative · entry 10

Phoenix Venture Partners II LP · CIK 0001647900 · 10% owner

Phoenix General Partner II LLC · CIK 0001874106 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 533,735 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_price: The Series A-2 Preferred Stock converted into Common Stock on a one-for-3.3031 basis and had no expiration date.

F4 · derivative.exercise_date: The Series A-2 Preferred Stock converted into Common Stock on a one-for-3.3031 basis and had no expiration date.

F4 · derivative.expiration_date: The Series A-2 Preferred Stock converted into Common Stock on a one-for-3.3031 basis and had no expiration date.

F2 · derivative.underlying_shares: Reflects one-for-3.3031 stock split which became effective on July 26, 2021.

F3 · ownership.direct: Phoenix General Partner II LLC, as the sole general partner of Phoenix Venture Partners II LP, beneficially owns the reported securities indirectly, but disclaims beneficial ownership of the reported securities except to the extent of its pecuniary interest therein.

SEC source: 0000899243-21-030340 · doc4.xml · derivative · entry 9

Phoenix Venture Partners II LP · CIK 0001647900 · 10% owner

Phoenix General Partner II LLC · CIK 0001874106 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 5,681,332 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: The Series A-1 Preferred Stock converted into Common Stock on a one-for-3.3031 basis and had no expiration date.

F1 · derivative.exercise_date: The Series A-1 Preferred Stock converted into Common Stock on a one-for-3.3031 basis and had no expiration date.

F1 · derivative.expiration_date: The Series A-1 Preferred Stock converted into Common Stock on a one-for-3.3031 basis and had no expiration date.

F2 · derivative.underlying_shares: Reflects one-for-3.3031 stock split which became effective on July 26, 2021.

F3 · ownership.direct: Phoenix General Partner II LLC, as the sole general partner of Phoenix Venture Partners II LP, beneficially owns the reported securities indirectly, but disclaims beneficial ownership of the reported securities except to the extent of its pecuniary interest therein.

SEC source: 0000899243-21-030340 · doc4.xml · nonDerivative · entry 8

Phoenix Venture Partners II LP · CIK 0001647900 · 10% owner

Phoenix General Partner II LLC · CIK 0001874106 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,185,602

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F10 · price: The Series E Preferred Stock converted into Common Stock on a one-for-3.3031 basis and had no expiration date.

F2 · balance_after: Reflects one-for-3.3031 stock split which became effective on July 26, 2021.

F3 · ownership.direct: Phoenix General Partner II LLC, as the sole general partner of Phoenix Venture Partners II LP, beneficially owns the reported securities indirectly, but disclaims beneficial ownership of the reported securities except to the extent of its pecuniary interest therein.

SEC source: 0000899243-21-030340 · doc4.xml · nonDerivative · entry 7

Phoenix Venture Partners II LP · CIK 0001647900 · 10% owner

Phoenix General Partner II LLC · CIK 0001874106 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,151,927

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F9 · price: The Series D-2 Preferred Stock converted into Common Stock on a one-for-3.3031 basis and had no expiration date.

F2 · balance_after: Reflects one-for-3.3031 stock split which became effective on July 26, 2021.

F3 · ownership.direct: Phoenix General Partner II LLC, as the sole general partner of Phoenix Venture Partners II LP, beneficially owns the reported securities indirectly, but disclaims beneficial ownership of the reported securities except to the extent of its pecuniary interest therein.

SEC source: 0000899243-21-030340 · doc4.xml · nonDerivative · entry 6

Phoenix Venture Partners II LP · CIK 0001647900 · 10% owner

Phoenix General Partner II LLC · CIK 0001874106 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,118,186

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F8 · price: The Series D-1 Preferred Stock converted into Common Stock on a one-for-3.3031 basis and had no expiration date.

F2 · balance_after: Reflects one-for-3.3031 stock split which became effective on July 26, 2021.

F3 · ownership.direct: Phoenix General Partner II LLC, as the sole general partner of Phoenix Venture Partners II LP, beneficially owns the reported securities indirectly, but disclaims beneficial ownership of the reported securities except to the extent of its pecuniary interest therein.

SEC source: 0000899243-21-030340 · doc4.xml · nonDerivative · entry 5

Phoenix Venture Partners II LP · CIK 0001647900 · 10% owner

Phoenix General Partner II LLC · CIK 0001874106 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,033,838

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · price: The Series C Preferred Stock converted into Common Stock on a one-for-3.3031 basis and had no expiration date.

F2 · balance_after: Reflects one-for-3.3031 stock split which became effective on July 26, 2021.

F3 · ownership.direct: Phoenix General Partner II LLC, as the sole general partner of Phoenix Venture Partners II LP, beneficially owns the reported securities indirectly, but disclaims beneficial ownership of the reported securities except to the extent of its pecuniary interest therein.

SEC source: 0000899243-21-030340 · doc4.xml · nonDerivative · entry 4

Phoenix Venture Partners II LP · CIK 0001647900 · 10% owner

Phoenix General Partner II LLC · CIK 0001874106 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,760,708

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · price: The Series B Preferred Stock converted into Common Stock on a one-for-3.3031 basis and had no expiration date.

F2 · balance_after: Reflects one-for-3.3031 stock split which became effective on July 26, 2021.

F3 · ownership.direct: Phoenix General Partner II LLC, as the sole general partner of Phoenix Venture Partners II LP, beneficially owns the reported securities indirectly, but disclaims beneficial ownership of the reported securities except to the extent of its pecuniary interest therein.

SEC source: 0000899243-21-030340 · doc4.xml · nonDerivative · entry 3

Phoenix Venture Partners II LP · CIK 0001647900 · 10% owner

Phoenix General Partner II LLC · CIK 0001874106 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,169,717

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · price: The Series A-3 Preferred Stock converted into Common Stock on a one-for-3.3031 basis and had no expiration date.

F2 · balance_after: Reflects one-for-3.3031 stock split which became effective on July 26, 2021.

F3 · ownership.direct: Phoenix General Partner II LLC, as the sole general partner of Phoenix Venture Partners II LP, beneficially owns the reported securities indirectly, but disclaims beneficial ownership of the reported securities except to the extent of its pecuniary interest therein.

SEC source: 0000899243-21-030340 · doc4.xml · nonDerivative · entry 2

Phoenix Venture Partners II LP · CIK 0001647900 · 10% owner

Phoenix General Partner II LLC · CIK 0001874106 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,215,067

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · price: The Series A-2 Preferred Stock converted into Common Stock on a one-for-3.3031 basis and had no expiration date.

F2 · balance_after: Reflects one-for-3.3031 stock split which became effective on July 26, 2021.

F3 · ownership.direct: Phoenix General Partner II LLC, as the sole general partner of Phoenix Venture Partners II LP, beneficially owns the reported securities indirectly, but disclaims beneficial ownership of the reported securities except to the extent of its pecuniary interest therein.

SEC source: 0000899243-21-030340 · doc4.xml · nonDerivative · entry 1

Phoenix Venture Partners II LP · CIK 0001647900 · 10% owner

Phoenix General Partner II LLC · CIK 0001874106 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,681,332

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: The Series A-1 Preferred Stock converted into Common Stock on a one-for-3.3031 basis and had no expiration date.

F2 · balance_after: Reflects one-for-3.3031 stock split which became effective on July 26, 2021.

F3 · ownership.direct: Phoenix General Partner II LLC, as the sole general partner of Phoenix Venture Partners II LP, beneficially owns the reported securities indirectly, but disclaims beneficial ownership of the reported securities except to the extent of its pecuniary interest therein.