Dunne Michael W.

SEC source: 0001193125-25-288848 · ownership.xml · nonDerivative · entry 1

Dunne Michael W. · CIK 0001553593 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 241,001

SEC source: 0000950170-25-106908 · ownership.xml · nonDerivative · entry 1

Dunne Michael W. · CIK 0001553593 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 235,001

SEC source: 0000950170-24-095096 · ownership.xml · derivative · entry 4

Dunne Michael W. · CIK 0001553593 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 106,247

Underlying: Ordinary Shares · 106,247 shares

Expires 2029-08-09

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: The reported securities were purchased in the Issuer's rights offering (the "Offering") which closed on August 9, 2024. As part of the Offering, the Reporting Person purchased 106,247 units at a subscription price of $1.21 per whole unit. Each unit consisted of (a) one ordinary share, (b) a warrant to purchase 0.50 ordinary shares, at an exercise price of $1.21 per whole ordinary share from the date of issuance through its expiration one year from the date of issuance ("1-year warrants"), and (c) a warrant to purchase one ordinary share, at an exercise price of $1.21 per whole ordinary share from the date of issuance through its expiration five years from the date of issuance ("5-year warrants").

SEC source: 0000950170-24-095096 · ownership.xml · derivative · entry 3

Dunne Michael W. · CIK 0001553593 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 106,247

Underlying: Ordinary Shares · 53,123 shares

Expires 2025-08-09

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: The reported securities were purchased in the Issuer's rights offering (the "Offering") which closed on August 9, 2024. As part of the Offering, the Reporting Person purchased 106,247 units at a subscription price of $1.21 per whole unit. Each unit consisted of (a) one ordinary share, (b) a warrant to purchase 0.50 ordinary shares, at an exercise price of $1.21 per whole ordinary share from the date of issuance through its expiration one year from the date of issuance ("1-year warrants"), and (c) a warrant to purchase one ordinary share, at an exercise price of $1.21 per whole ordinary share from the date of issuance through its expiration five years from the date of issuance ("5-year warrants").

SEC source: 0000950170-24-095096 · ownership.xml · derivative · entry 2

Dunne Michael W. · CIK 0001553593 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Units · Not disclosed shares

Expires 2024-08-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.underlying_shares: The Reporting Person validly exercised 212,494 subscription rights to acquire 106,247 units composed of (i) 106,247 ordinary shares, (ii) 106,247 1-year warrants and (iii) 106,247 5-year warrants.

SEC source: 0000950170-24-095096 · ownership.xml · nonDerivative · entry 1

Dunne Michael W. · CIK 0001553593 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 220,001

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: The reported securities were purchased in the Issuer's rights offering (the "Offering") which closed on August 9, 2024. As part of the Offering, the Reporting Person purchased 106,247 units at a subscription price of $1.21 per whole unit. Each unit consisted of (a) one ordinary share, (b) a warrant to purchase 0.50 ordinary shares, at an exercise price of $1.21 per whole ordinary share from the date of issuance through its expiration one year from the date of issuance ("1-year warrants"), and (c) a warrant to purchase one ordinary share, at an exercise price of $1.21 per whole ordinary share from the date of issuance through its expiration five years from the date of issuance ("5-year warrants").

SEC source: 0001209191-23-059750 · doc4.xml · nonDerivative · entry 1

Dunne Michael W. · CIK 0001553593 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 113,754

SEC source: 0001209191-23-059133 · doc4.xml · nonDerivative · entry 1

Dunne Michael W. · CIK 0001553593 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 88,754

F1 · price: The price reported is a weighted average price. The securities were purchased in multiple transactions at per share prices ranging from $1.795 to $1.85. The Reporting Person undertakes to provide upon request of the SEC staff, the Issuer, or any shareholder of the Issuer, full information requiring the number of securities purchased at each separate price within the range set forth in this footnote.

SEC source: 0001209191-23-056685 · doc4.xml · nonDerivative · entry 1

Dunne Michael W. · CIK 0001553593 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 78,754

F1 · price: The price reported is a weighted average price. The securities were purchased in multiple transactions at per share prices ranging from $1.93 to $2.11. The Reporting Person undertakes to provide upon request the SEC staff, the Issuer, or any shareholder of the Issuer, full information regarding the number of securities purchased at each separate price within the range set forth in this footnote.

SEC source: 0001209191-23-050911 · doc4.xml · derivative · entry 2

Dunne Michael W. · CIK 0001553593 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Ordinary Shares · 3,487 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Restricted share units ("RSUs") converted into ordinary shares on a one-for-one basis upon vesting of the RSUs.

F2 · derivative.exercise_date: On December 23, 2022, the reporting person was granted an award of 3,487 RSUs, which vested in full on October 1, 2023.

F2 · derivative.expiration_date: On December 23, 2022, the reporting person was granted an award of 3,487 RSUs, which vested in full on October 1, 2023.

SEC source: 0001209191-23-050911 · doc4.xml · nonDerivative · entry 1

Dunne Michael W. · CIK 0001553593 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 58,754

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Restricted share units ("RSUs") converted into ordinary shares on a one-for-one basis upon vesting of the RSUs.

SEC source: 0001209191-23-040406 · doc4.xml · derivative · entry 2

Dunne Michael W. · CIK 0001553593 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Ordinary Shares · 1,779 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Restricted share units ("RSUs") converted into ordinary shares on a one-for-one basis upon vesting of the RSUs.

F2 · derivative.exercise_date: On September 25, 2022, the reporting person was granted an award of 1,799 RSUs, which vested in full on July 1, 2023.

F2 · derivative.expiration_date: On September 25, 2022, the reporting person was granted an award of 1,799 RSUs, which vested in full on July 1, 2023.

SEC source: 0001209191-23-040406 · doc4.xml · nonDerivative · entry 1

Dunne Michael W. · CIK 0001553593 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 55,267

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Restricted share units ("RSUs") converted into ordinary shares on a one-for-one basis upon vesting of the RSUs.

SEC source: 0001209191-23-037407 · doc4.xml · derivative · entry 2

Dunne Michael W. · CIK 0001553593 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Ordinary Shares · 15,853 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Restricted share units ("RSUs") converted into ordinary shares on a one-for-one basis upon vesting of the RSUs.

F2 · derivative.exercise_date: On June 15, 2022, the reporting person was granted an award of 15,853 RSUs, which vested in full on June 15, 2023.

F2 · derivative.expiration_date: On June 15, 2022, the reporting person was granted an award of 15,853 RSUs, which vested in full on June 15, 2023.

F3 · derivative.underlying_shares: On August 17, 2022 the Issuer effected a 1 for 15 reverse share split (the "Reverse Share Split"). The number of ordinary shares reported in this Form 4 have been adjusted to reflect the Reverse Share Split.

SEC source: 0001209191-23-037407 · doc4.xml · nonDerivative · entry 1

Dunne Michael W. · CIK 0001553593 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 53,488

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Restricted share units ("RSUs") converted into ordinary shares on a one-for-one basis upon vesting of the RSUs.

SEC source: 0001209191-23-022422 · doc4.xml · derivative · entry 2

Dunne Michael W. · CIK 0001553593 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Ordinary Shares · 1,299 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Restricted share units ("RSUs") converted into ordinary shares on a one-for-one basis upon vesting of the RSUs.

F2 · derivative.exercise_date: On June 25, 2022, the reporting person was granted an award of 1,299 RSUs, which vested in full on April 1, 2023.

F2 · derivative.expiration_date: On June 25, 2022, the reporting person was granted an award of 1,299 RSUs, which vested in full on April 1, 2023.

F3 · derivative.underlying_shares: On August 17, 2022 the Issuer effected a 1 for 15 reverse share split (the "Reverse Share Split"). The number of ordinary shares reported in this Form 4 have been adjusted to reflect the Reverse Share Split.

SEC source: 0001209191-23-022422 · doc4.xml · nonDerivative · entry 1

Dunne Michael W. · CIK 0001553593 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 37,636

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Restricted share units ("RSUs") converted into ordinary shares on a one-for-one basis upon vesting of the RSUs.

SEC source: 0001209191-23-034106 · doc4a.xml · nonDerivative · entry 1

Dunne Michael W. · CIK 0001553593 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 37,635

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Restricted share units ("RSUs") converted into ordinary shares on a one-for-one basis upon vesting of the RSUs.

F2 · balance_after: This amendment is being filed solely to correct an error in the Amount of Securities Beneficially Owned Following Reported Transaction in the original Form 4, as filed on April 3, 2023. The Amount of Securities Beneficially Owned Following Reported Transaction on April 1, 2023, which were reported as 37,636, should have been reported as 37,635.

SEC source: 0001209191-23-001287 · doc4.xml · derivative · entry 2

Dunne Michael W. · CIK 0001553593 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Ordinary Shares · 761 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Restricted share units ("RSUs") converted into ordinary shares on a one-for-one basis upon vesting of the RSUs.

F2 · derivative.exercise_date: On March 25, 2022, the reporting person was granted an award of 11,426 RSUs (the "RSU Grant"), which vested on January 1, 2023.

F2 · derivative.expiration_date: On March 25, 2022, the reporting person was granted an award of 11,426 RSUs (the "RSU Grant"), which vested on January 1, 2023.

F3 · derivative.underlying_shares: On August 17, 2022 the Issuer effected a 1 for 15 reverse share split (the "Reverse Share Split"). The number of ordinary shares underlying the RSU Grant have been adjusted to reflect the Reverse Share Split.

SEC source: 0001209191-23-001287 · doc4.xml · nonDerivative · entry 1

Dunne Michael W. · CIK 0001553593 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,337

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Restricted share units ("RSUs") converted into ordinary shares on a one-for-one basis upon vesting of the RSUs.

SEC source: 0001209191-22-062871 · doc4.xml · derivative · entry 1

Dunne Michael W. · CIK 0001553593 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,487

Underlying: Ordinary Shares · 3,487 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted share unit ("RSU") represents the contingent right to receive one ordinary share upon vesting of the RSU.

F2 · derivative.exercise_date: Subject to the reporting person providing continuous service to the Issuer and the other terms and conditions of the Issuer's 2018 Amended and Restated Equity Incentive Plan, as amended, the RSUs shall vest in full on October 1, 2023.

F2 · derivative.expiration_date: Subject to the reporting person providing continuous service to the Issuer and the other terms and conditions of the Issuer's 2018 Amended and Restated Equity Incentive Plan, as amended, the RSUs shall vest in full on October 1, 2023.

SEC source: 0001209191-22-051416 · doc4.xml · derivative · entry 1

Dunne Michael W. · CIK 0001553593 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,779

Underlying: Ordinary Shares · 1,779 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted share unit ("RSU") represents the contingent right to receive one ordinary share upon vesting of the RSU.

F2 · derivative.exercise_date: Subject to the reporting person providing continuous service to the Issuer and the other terms and conditions of the Issuer's 2018 Amended and Restated 2018 Equity Incentive Plan, as amended, the RSUs shall vest in full on July 1, 2023.

F2 · derivative.expiration_date: Subject to the reporting person providing continuous service to the Issuer and the other terms and conditions of the Issuer's 2018 Amended and Restated 2018 Equity Incentive Plan, as amended, the RSUs shall vest in full on July 1, 2023.

SEC source: 0001209191-22-049352 · doc4.xml · nonDerivative · entry 1

Dunne Michael W. · CIK 0001553593 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 35,576

F1 · balance_after: On August 17, 2022 the Issuer effected a 1 for 15 reverse share split (the "Reverse Share Split"). The number of ordinary shares reported on this Form 4 have been adjusted to reflect the Reverse Share Split.

SEC source: 0001209191-22-039706 · doc4.xml · derivative · entry 1

Dunne Michael W. · CIK 0001553593 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,488

Underlying: Ordinary Shares · 19,488 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted share unit ("RSU") represents the contingent right to receive one ordinary share upon vesting of the RSU.

F2 · derivative.exercise_date: Subject to the reporting person providing continuous service to the Issuer and the other terms and conditions of the Issuer's 2018 Amended and Restated Equity Incentive Plan, as amended, the RSUs shall vest in full on April 1, 2023.

F2 · derivative.expiration_date: Subject to the reporting person providing continuous service to the Issuer and the other terms and conditions of the Issuer's 2018 Amended and Restated Equity Incentive Plan, as amended, the RSUs shall vest in full on April 1, 2023.

SEC source: 0001209191-22-039312 · doc4.xml · derivative · entry 2

Dunne Michael W. · CIK 0001553593 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Ordinary Shares · 36,798 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Restricted share units ("RSUs") converted into ordinary shares on a one-for-one basis upon vesting of the RSUs.

F2 · derivative.exercise_date: On June 23, 2021, the reporting person was granted an award of 36,798 RSUs, which vested on June 23, 2022.

F2 · derivative.expiration_date: On June 23, 2021, the reporting person was granted an award of 36,798 RSUs, which vested on June 23, 2022.

SEC source: 0001209191-22-039312 · doc4.xml · nonDerivative · entry 1

Dunne Michael W. · CIK 0001553593 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 383,647

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Restricted share units ("RSUs") converted into ordinary shares on a one-for-one basis upon vesting of the RSUs.

SEC source: 0001209191-22-037937 · doc4.xml · derivative · entry 1

Dunne Michael W. · CIK 0001553593 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 237,795

Underlying: Ordinary Shares · 237,795 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted share unit ("RSU") represents the contingent right to receive one ordinary share upon vesting of the RSU.

F2 · derivative.exercise_date: Subject to the reporting person providing continuous service to the Issuer and the other terms and conditions of the Issuer's 2018 Amended and Restated Equity Incentive Plan, as amended, the RSUs shall vest in full on June 15, 2023.

F2 · derivative.expiration_date: Subject to the reporting person providing continuous service to the Issuer and the other terms and conditions of the Issuer's 2018 Amended and Restated Equity Incentive Plan, as amended, the RSUs shall vest in full on June 15, 2023.

SEC source: 0001209191-22-021542 · doc4.xml · derivative · entry 3

Dunne Michael W. · CIK 0001553593 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,426

Underlying: Ordinary Shares · 11,426 shares

Expires not disclosed

F3 · derivative.exercise_price: Each restricted share unit ("2022 RSU") represents the contingent right to receive one ordinary share upon vesting of a 2022 RSU.

F4 · derivative.exercise_date: Subject to the reporting person providing continuous service to the Issuer and the other terms and conditions of the Issuer's 2018 Amended and Restated Equity Incentive Plan, as amended, the 2022 RSUs shall vest in full on January 1, 2023.

F4 · derivative.expiration_date: Subject to the reporting person providing continuous service to the Issuer and the other terms and conditions of the Issuer's 2018 Amended and Restated Equity Incentive Plan, as amended, the 2022 RSUs shall vest in full on January 1, 2023.

SEC source: 0001209191-22-021542 · doc4.xml · derivative · entry 2

Dunne Michael W. · CIK 0001553593 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Ordinary Shares · 10,494 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Restricted share units ("2021 RSUs") converted into ordinary shares on a one-for-one basis upon vesting of the 2021 RSUs.

F2 · derivative.exercise_date: On March 25, 2021, the reporting person was granted an award of 10,494 2021 RSUs, which vested on March 25, 2022.

F2 · derivative.expiration_date: On March 25, 2021, the reporting person was granted an award of 10,494 2021 RSUs, which vested on March 25, 2022.

SEC source: 0001209191-22-021542 · doc4.xml · nonDerivative · entry 1

Dunne Michael W. · CIK 0001553593 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 346,849

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Restricted share units ("2021 RSUs") converted into ordinary shares on a one-for-one basis upon vesting of the 2021 RSUs.

SEC source: 0000899243-21-030223 · doc4.xml · nonDerivative · entry 1

Dunne Michael W. · CIK 0001553593 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 336,355

F1 · shares: Consists of 80,000 ordinary shares received upon vesting of performance-based stock units ("PSUs") on July 25, 2021, which PSUs were subject to performance conditions that have been satisfied. PSUs convert into ordinary shares on a one-for-one basis.

SEC source: 0000899243-21-025953 · doc4.xml · derivative · entry 1

Dunne Michael W. · CIK 0001553593 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,798

Underlying: Ordinary Shares · 36,798 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted share unit ("RSU") represents the contingent right to receive one ordinary share upon vesting of the RSU.

F2 · derivative.exercise_date: Subject to the reporting person providing continuous service to the Issuer and the other terms and conditions of the Issuer's 2018 Amended and Restated Equity Incentive Plan, as amended, the RSUs shall vest in full on June 23, 2022.

F2 · derivative.expiration_date: Subject to the reporting person providing continuous service to the Issuer and the other terms and conditions of the Issuer's 2018 Amended and Restated Equity Incentive Plan, as amended, the RSUs shall vest in full on June 23, 2022.

SEC source: 0000899243-21-013822 · doc4.xml · derivative · entry 1

Dunne Michael W. · CIK 0001553593 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,494

Underlying: Ordinary Shares · 10,494 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted share unit ("RSU") represents the contingent right to receive one ordinary share upon vesting of the RSU.

F2 · derivative.exercise_date: Subject to the reporting person providing continuous service to the Issuer and the other terms and conditions of the Issuer's 2018 Amended and Restated Equity Incentive Plan, the RSUs shall vest on March 25, 2022.

F2 · derivative.expiration_date: Subject to the reporting person providing continuous service to the Issuer and the other terms and conditions of the Issuer's 2018 Amended and Restated Equity Incentive Plan, the RSUs shall vest on March 25, 2022.

SEC source: 0000899243-21-003519 · doc4.xml · nonDerivative · entry 2

Dunne Michael W. · CIK 0001553593 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 256,355

F2 · shares: Represents the shares automatically sold by the reporting person pursuant to an election to satisfy tax withholding obligations in connection with the vesting of the PSUs. This sale does not represent a discretionary trade by the reporting person.

SEC source: 0000899243-21-003519 · doc4.xml · nonDerivative · entry 1

Dunne Michael W. · CIK 0001553593 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 289,498

F1 · shares: Consists of 80,000 ordinary shares received upon vesting of performance-based stock units ("PSUs") on January 25, 2021, which PSUs were subject to performance conditions that have been satisfied. PSUs convert into ordinary shares on a one-for-one basis.

SEC source: 0000899243-20-029501 · doc4.xml · derivative · entry 2

Dunne Michael W. · CIK 0001553593 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 46,155

Underlying: Ordinary Shares · 46,155 shares

Expires 2025-10-27

F1 · price: The reported securities were purchased in the Issuer's registered public offering on October 27, 2020 at a combined purchase price of $0.65 per ordinary share and warrant. Each ordinary share was purchased together with a warrant to purchase 0.75 of an ordinary share.

SEC source: 0000899243-20-029501 · doc4.xml · nonDerivative · entry 1

Dunne Michael W. · CIK 0001553593 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 209,498

F1 · price: The reported securities were purchased in the Issuer's registered public offering on October 27, 2020 at a combined purchase price of $0.65 per ordinary share and warrant. Each ordinary share was purchased together with a warrant to purchase 0.75 of an ordinary share.

SEC source: 0000899243-19-003972 · doc4.xml · derivative · entry 1

Dunne Michael W. · CIK 0001553593 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 85,000

Underlying: Ordinary Shares · 85,000 shares

Expires 2029-02-14

F1 · derivative.exercise_date: The shares subject to this option shall vest at a rate of twenty-five percent of the total number of shares on the one-year anniversary of February 15, 2019 (the "Vesting Commencement Date") and 1/48th of the total number of shares each monthly anniversary of the Vesting Commencement Date thereafter for so long as the Reporting Person provides continuous service to the Issuer, such that the total number of shares shall be fully vested on the four-year anniversary of the Vesting Commencement Date.

SEC source: 0001209191-18-049884 · doc4.xml · nonDerivative · entry 1

Dunne Michael W. · CIK 0001553593 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 147,958

SEC source: 0001209191-18-048708 · doc4.xml · nonDerivative · entry 2

Dunne Michael W. · CIK 0001553593 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 147,458

SEC source: 0001209191-18-048708 · doc4.xml · nonDerivative · entry 1

Dunne Michael W. · CIK 0001553593 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 146,958

SEC source: 0001209191-18-034172 · doc4.xml · derivative · entry 7

Dunne Michael W. · CIK 0001553593 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Ordinary Shares · 2,917 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: The Series B-2 Preferred Shares automatically converted into Ordinary Shares of the Issuer on a 1-to-1 basis upon closing of the initial public offering of the Issuer.

F3 · derivative.exercise_date: The Series B-2 Preferred Shares automatically converted into Ordinary Shares of the Issuer on a 1-to-1 basis upon closing of the initial public offering of the Issuer.

F4 · derivative.expiration_date: Not applicable.

SEC source: 0001209191-18-034172 · doc4.xml · derivative · entry 6

Dunne Michael W. · CIK 0001553593 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Ordinary Shares · 4,050 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: The Series B-1 Preferred Shares automatically converted into Ordinary Shares of the Issuer on a 1-to-1 basis upon closing of the initial public offering of the Issuer.

F2 · derivative.exercise_date: The Series B-1 Preferred Shares automatically converted into Ordinary Shares of the Issuer on a 1-to-1 basis upon closing of the initial public offering of the Issuer.

F4 · derivative.expiration_date: Not applicable.

SEC source: 0001209191-18-034172 · doc4.xml · derivative · entry 5

Dunne Michael W. · CIK 0001553593 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Ordinary Shares · 12,730 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: The Series A Preferred Shares automatically converted into Ordinary Shares of the Issuer on a 1-to-1 basis upon closing of the initial public offering of the Issuer.

F1 · derivative.exercise_date: The Series A Preferred Shares automatically converted into Ordinary Shares of the Issuer on a 1-to-1 basis upon closing of the initial public offering of the Issuer.

F4 · derivative.expiration_date: Not applicable.

SEC source: 0001209191-18-034172 · doc4.xml · nonDerivative · entry 4

Dunne Michael W. · CIK 0001553593 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 146,458

SEC source: 0001209191-18-034172 · doc4.xml · nonDerivative · entry 3

Dunne Michael W. · CIK 0001553593 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 144,458

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · price: The Series B-2 Preferred Shares automatically converted into Ordinary Shares of the Issuer on a 1-to-1 basis upon closing of the initial public offering of the Issuer.

SEC source: 0001209191-18-034172 · doc4.xml · nonDerivative · entry 2

Dunne Michael W. · CIK 0001553593 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 141,541

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · price: The Series B-1 Preferred Shares automatically converted into Ordinary Shares of the Issuer on a 1-to-1 basis upon closing of the initial public offering of the Issuer.

SEC source: 0001209191-18-034172 · doc4.xml · nonDerivative · entry 1

Dunne Michael W. · CIK 0001553593 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 137,491

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: The Series A Preferred Shares automatically converted into Ordinary Shares of the Issuer on a 1-to-1 basis upon closing of the initial public offering of the Issuer.

SEC source: 0001209191-18-033905 · doc4.xml · derivative · entry 1

Dunne Michael W. · CIK 0001553593 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 79,567

Underlying: Ordinary Shares · 79,567 shares

Expires 2028-05-23

F1 · derivative.exercise_date: The shares subject to this option shall vest at a rate of twenty-five percent of the total number of shares on the one-year anniversary of May 24, 2018 (the "Vesting Commencement Date") and 1/48th of the total number of shares each monthly anniversary of the Vesting Commencement Date thereafter for so long as the Reporting Person provides continuous service to the Issuer, such that the total number of shares shall be fully vested on the four-year anniversary of the Vesting Commencement Date.

SEC source: 0001437749-17-009784 · rdgdoc.xml · derivative · entry 1

Dunne Michael W. · CIK 0001553593 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 75,000

Underlying: Common Stock · 20,000 shares

Expires 2027-05-18