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Gharib Samir M.

Disclosed activity across 1 company

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71314
SEC CIK
0001533302

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CompanyLast reported asReport datePublished
SPRUCE BIOSCIENCES, INC.SPRB · Entity 6471PRESIDENT AND CFODecember 15, 2025December 17, 2025

Disclosed balances

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Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

SPRUCE BIOSCIENCES, INC.

Report date December 15, 2025 · Filed December 17, 2025

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect8,263 Ending reported balance After 2025-12-15 transaction · row 4
4 source rows · reconciled sequence

Row 1 · 2025-12-15 · Exercise / conversion · Acquired 496 · Balance 8,112

F1: On December 5, 2022, the Reporting Person was granted 1,986 time-based restricted stock units ("RSUs"), subject to a 4-year vesting schedule, with 25% of the total number of RSUs vested on December 15, 2023 (the "Annual Vesting Date") and 25% of the total number of RSUs to vest in annual installments on each anniversary of the Annual Vesting Date thereafter, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On December 15, 2025, 496 RSUs vested, with 178 shares withheld for taxes, resulting in a net issuance of 318 shares.

F2: Each RSU represents a contingent right to receive one share of common stock of the Issuer.

Row 2 · 2025-12-15 · Tax withholding · Disposed 178 · Balance 7,934

F1: On December 5, 2022, the Reporting Person was granted 1,986 time-based restricted stock units ("RSUs"), subject to a 4-year vesting schedule, with 25% of the total number of RSUs vested on December 15, 2023 (the "Annual Vesting Date") and 25% of the total number of RSUs to vest in annual installments on each anniversary of the Annual Vesting Date thereafter, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On December 15, 2025, 496 RSUs vested, with 178 shares withheld for taxes, resulting in a net issuance of 318 shares.

Row 3 · 2025-12-15 · Exercise / conversion · Acquired 513 · Balance 8,447

F3: On December 14, 2023, the Reporting Person was granted a total of 4,106 RSUs. 50% or 2,053 of the total RSUs are performance-based and all vested on December 10, 2024. An addition of 50% or 2,053 of the total RSUs are time-based. 25% of which vested on December 15, 2024, and in equal annual installments thereafter, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On December 15, 2025, 513 shares vested and 184 shares were withheld for taxes, resulting in a net issuance of 329 shares.

F2: Each RSU represents a contingent right to receive one share of common stock of the Issuer.

Row 4 · 2025-12-15 · Tax withholding · Disposed 184 · Balance 8,263

F3: On December 14, 2023, the Reporting Person was granted a total of 4,106 RSUs. 50% or 2,053 of the total RSUs are performance-based and all vested on December 10, 2024. An addition of 50% or 2,053 of the total RSUs are time-based. 25% of which vested on December 15, 2024, and in equal annual installments thereafter, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On December 15, 2025, 513 shares vested and 184 shares were withheld for taxes, resulting in a net issuance of 329 shares.

Restricted Stock UnitsSEC Table II · derivative / convertible security · Conversion / exercise price $0.00Direct497 Reported balance After 2025-12-15 transaction · row 5 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 5 · 2025-12-15 · Exercise / conversion · Disposed 496 · Balance 497

F2: Each RSU represents a contingent right to receive one share of common stock of the Issuer.

F1: On December 5, 2022, the Reporting Person was granted 1,986 time-based restricted stock units ("RSUs"), subject to a 4-year vesting schedule, with 25% of the total number of RSUs vested on December 15, 2023 (the "Annual Vesting Date") and 25% of the total number of RSUs to vest in annual installments on each anniversary of the Annual Vesting Date thereafter, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On December 15, 2025, 496 RSUs vested, with 178 shares withheld for taxes, resulting in a net issuance of 318 shares.

Restricted Stock UnitsSEC Table II · derivative / convertible security · Conversion / exercise price $0.00Direct1,027 Reported balance After 2025-12-15 transaction · row 6 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 6 · 2025-12-15 · Exercise / conversion · Disposed 513 · Balance 1,027

F2: Each RSU represents a contingent right to receive one share of common stock of the Issuer.

F3: On December 14, 2023, the Reporting Person was granted a total of 4,106 RSUs. 50% or 2,053 of the total RSUs are performance-based and all vested on December 10, 2024. An addition of 50% or 2,053 of the total RSUs are time-based. 25% of which vested on December 15, 2024, and in equal annual installments thereafter, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On December 15, 2025, 513 shares vested and 184 shares were withheld for taxes, resulting in a net issuance of 329 shares.

Filing footnotes · ownership attribution and instrument terms

F1: On December 5, 2022, the Reporting Person was granted 1,986 time-based restricted stock units ("RSUs"), subject to a 4-year vesting schedule, with 25% of the total number of RSUs vested on December 15, 2023 (the "Annual Vesting Date") and 25% of the total number of RSUs to vest in annual installments on each anniversary of the Annual Vesting Date thereafter, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On December 15, 2025, 496 RSUs vested, with 178 shares withheld for taxes, resulting in a net issuance of 318 shares.

F2: Each RSU represents a contingent right to receive one share of common stock of the Issuer.

F3: On December 14, 2023, the Reporting Person was granted a total of 4,106 RSUs. 50% or 2,053 of the total RSUs are performance-based and all vested on December 10, 2024. An addition of 50% or 2,053 of the total RSUs are time-based. 25% of which vested on December 15, 2024, and in equal annual installments thereafter, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On December 15, 2025, 513 shares vested and 184 shares were withheld for taxes, resulting in a net issuance of 329 shares.

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

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Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
December 15, 2025 Filed Dec 17, 2025 21:58 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 Exercise / conversionRestricted Stock Units · Derivative 513 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001533302-25-000011 · form4-12172025_091247.xml · derivative · entry 6

Gharib Samir M. · CIK 0001533302 · PRESIDENT AND CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,027

Underlying: Common Stock · 513 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each RSU represents a contingent right to receive one share of common stock of the Issuer.

F3 · derivative.exercise_date: On December 14, 2023, the Reporting Person was granted a total of 4,106 RSUs. 50% or 2,053 of the total RSUs are performance-based and all vested on December 10, 2024. An addition of 50% or 2,053 of the total RSUs are time-based. 25% of which vested on December 15, 2024, and in equal annual installments thereafter, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On December 15, 2025, 513 shares vested and 184 shares were withheld for taxes, resulting in a net issuance of 329 shares.

F3 · derivative.expiration_date: On December 14, 2023, the Reporting Person was granted a total of 4,106 RSUs. 50% or 2,053 of the total RSUs are performance-based and all vested on December 10, 2024. An addition of 50% or 2,053 of the total RSUs are time-based. 25% of which vested on December 15, 2024, and in equal annual installments thereafter, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On December 15, 2025, 513 shares vested and 184 shares were withheld for taxes, resulting in a net issuance of 329 shares.

Read SEC document
December 15, 2025 Filed Dec 17, 2025 21:58 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 Exercise / conversionRestricted Stock Units · Derivative 496 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001533302-25-000011 · form4-12172025_091247.xml · derivative · entry 5

Gharib Samir M. · CIK 0001533302 · PRESIDENT AND CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 497

Underlying: Common Stock · 496 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each RSU represents a contingent right to receive one share of common stock of the Issuer.

F1 · derivative.exercise_date: On December 5, 2022, the Reporting Person was granted 1,986 time-based restricted stock units ("RSUs"), subject to a 4-year vesting schedule, with 25% of the total number of RSUs vested on December 15, 2023 (the "Annual Vesting Date") and 25% of the total number of RSUs to vest in annual installments on each anniversary of the Annual Vesting Date thereafter, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On December 15, 2025, 496 RSUs vested, with 178 shares withheld for taxes, resulting in a net issuance of 318 shares.

F1 · derivative.expiration_date: On December 5, 2022, the Reporting Person was granted 1,986 time-based restricted stock units ("RSUs"), subject to a 4-year vesting schedule, with 25% of the total number of RSUs vested on December 15, 2023 (the "Annual Vesting Date") and 25% of the total number of RSUs to vest in annual installments on each anniversary of the Annual Vesting Date thereafter, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On December 15, 2025, 496 RSUs vested, with 178 shares withheld for taxes, resulting in a net issuance of 318 shares.

Read SEC document
December 15, 2025 Filed Dec 17, 2025 21:58 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 Tax withholdingCommon Stock 184 $80.67 $14,843.28
Disclosure

SEC source: 0001533302-25-000011 · form4-12172025_091247.xml · nonDerivative · entry 4

Gharib Samir M. · CIK 0001533302 · PRESIDENT AND CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,263

F3 · shares: On December 14, 2023, the Reporting Person was granted a total of 4,106 RSUs. 50% or 2,053 of the total RSUs are performance-based and all vested on December 10, 2024. An addition of 50% or 2,053 of the total RSUs are time-based. 25% of which vested on December 15, 2024, and in equal annual installments thereafter, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On December 15, 2025, 513 shares vested and 184 shares were withheld for taxes, resulting in a net issuance of 329 shares.

Read SEC document
December 15, 2025 Filed Dec 17, 2025 21:58 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 Exercise / conversionCommon Stock 513 $0.00 $0.00
Disclosure

SEC source: 0001533302-25-000011 · form4-12172025_091247.xml · nonDerivative · entry 3

Gharib Samir M. · CIK 0001533302 · PRESIDENT AND CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,447

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · shares: On December 14, 2023, the Reporting Person was granted a total of 4,106 RSUs. 50% or 2,053 of the total RSUs are performance-based and all vested on December 10, 2024. An addition of 50% or 2,053 of the total RSUs are time-based. 25% of which vested on December 15, 2024, and in equal annual installments thereafter, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On December 15, 2025, 513 shares vested and 184 shares were withheld for taxes, resulting in a net issuance of 329 shares.

F2 · price: Each RSU represents a contingent right to receive one share of common stock of the Issuer.

Read SEC document
December 15, 2025 Filed Dec 17, 2025 21:58 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 Tax withholdingCommon Stock 178 $80.67 $14,359.26
Disclosure

SEC source: 0001533302-25-000011 · form4-12172025_091247.xml · nonDerivative · entry 2

Gharib Samir M. · CIK 0001533302 · PRESIDENT AND CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,934

F1 · shares: On December 5, 2022, the Reporting Person was granted 1,986 time-based restricted stock units ("RSUs"), subject to a 4-year vesting schedule, with 25% of the total number of RSUs vested on December 15, 2023 (the "Annual Vesting Date") and 25% of the total number of RSUs to vest in annual installments on each anniversary of the Annual Vesting Date thereafter, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On December 15, 2025, 496 RSUs vested, with 178 shares withheld for taxes, resulting in a net issuance of 318 shares.

Read SEC document
December 15, 2025 Filed Dec 17, 2025 21:58 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 Exercise / conversionCommon Stock 496 $0.00 $0.00
Disclosure

SEC source: 0001533302-25-000011 · form4-12172025_091247.xml · nonDerivative · entry 1

Gharib Samir M. · CIK 0001533302 · PRESIDENT AND CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,112

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: On December 5, 2022, the Reporting Person was granted 1,986 time-based restricted stock units ("RSUs"), subject to a 4-year vesting schedule, with 25% of the total number of RSUs vested on December 15, 2023 (the "Annual Vesting Date") and 25% of the total number of RSUs to vest in annual installments on each anniversary of the Annual Vesting Date thereafter, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On December 15, 2025, 496 RSUs vested, with 178 shares withheld for taxes, resulting in a net issuance of 318 shares.

F2 · price: Each RSU represents a contingent right to receive one share of common stock of the Issuer.

Read SEC document
December 11, 2025 Filed Dec 13, 2025 00:05 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 Exercise / conversionRestricted Stock Units · Derivative 1,900 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001533302-25-000007 · form4-12132025_121236.xml · derivative · entry 7

Gharib Samir M. · CIK 0001533302 · PRESIDENT AND CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,700

Underlying: Common Stock · 1,900 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each RSU represents a contingent right to receive one share of SPRB common stock.

F3 · derivative.exercise_date: 25% of the total number of RSUs vested on grant. 25% of the total number of RSUs will vest on December 15, 2026, December 15, 2027 and December 15, 2028, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan) as of each such vesting date. On December 11, 2025, 1,900 shares vested and 680 shares were withheld for taxes, resulting in a net issuance of 1,220 shares.

F3 · derivative.expiration_date: 25% of the total number of RSUs vested on grant. 25% of the total number of RSUs will vest on December 15, 2026, December 15, 2027 and December 15, 2028, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan) as of each such vesting date. On December 11, 2025, 1,900 shares vested and 680 shares were withheld for taxes, resulting in a net issuance of 1,220 shares.

Read SEC document
December 11, 2025 Filed Dec 13, 2025 00:05 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 GrantRestricted Stock Units · Derivative 7,600 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001533302-25-000007 · form4-12132025_121236.xml · derivative · entry 6

Gharib Samir M. · CIK 0001533302 · PRESIDENT AND CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,600

Underlying: Common Stock · 7,600 shares

Expires not disclosed

F2 · derivative.exercise_price: Each RSU represents a contingent right to receive one share of SPRB common stock.

F3 · derivative.exercise_date: 25% of the total number of RSUs vested on grant. 25% of the total number of RSUs will vest on December 15, 2026, December 15, 2027 and December 15, 2028, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan) as of each such vesting date. On December 11, 2025, 1,900 shares vested and 680 shares were withheld for taxes, resulting in a net issuance of 1,220 shares.

F3 · derivative.expiration_date: 25% of the total number of RSUs vested on grant. 25% of the total number of RSUs will vest on December 15, 2026, December 15, 2027 and December 15, 2028, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan) as of each such vesting date. On December 11, 2025, 1,900 shares vested and 680 shares were withheld for taxes, resulting in a net issuance of 1,220 shares.

Read SEC document
December 11, 2025 Filed Dec 13, 2025 00:05 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 Tax withholdingCommon Stock 680 $88.41 $60,118.80
Disclosure

SEC source: 0001533302-25-000007 · form4-12132025_121236.xml · nonDerivative · entry 4

Gharib Samir M. · CIK 0001533302 · PRESIDENT AND CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,616

F3 · shares: 25% of the total number of RSUs vested on grant. 25% of the total number of RSUs will vest on December 15, 2026, December 15, 2027 and December 15, 2028, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan) as of each such vesting date. On December 11, 2025, 1,900 shares vested and 680 shares were withheld for taxes, resulting in a net issuance of 1,220 shares.

Read SEC document
December 11, 2025 Filed Dec 13, 2025 00:05 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 Exercise / conversionCommon Stock 1,900 $0.00 $0.00
Disclosure

SEC source: 0001533302-25-000007 · form4-12132025_121236.xml · nonDerivative · entry 3

Gharib Samir M. · CIK 0001533302 · PRESIDENT AND CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,296

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · shares: 25% of the total number of RSUs vested on grant. 25% of the total number of RSUs will vest on December 15, 2026, December 15, 2027 and December 15, 2028, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan) as of each such vesting date. On December 11, 2025, 1,900 shares vested and 680 shares were withheld for taxes, resulting in a net issuance of 1,220 shares.

F2 · price: Each RSU represents a contingent right to receive one share of SPRB common stock.

Read SEC document
December 11, 2025 Filed Dec 15, 2025 23:54 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 Disposition to issuerStock Option (Right to Buy) · Derivative 933 Not disclosed Strike: $344.25 Not disclosed
Disclosure

SEC source: 0001533302-25-000009 · form4-12152025_111246.xml · derivative · entry 10

Gharib Samir M. · CIK 0001533302 · PRESIDENT AND CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 933 shares

Expires 2032-01-02

F2 · price: The transactions reported herein reflect a one-time stock option repricing (the "Option Repricing") effective on December 11, 2025 (the "Repricing Date"). The Option Repricing applies to options with exercise prices of $106.09 per share or greater held by employees and directors of the Issuer who remained in continuous service with the Company as of the Repricing Date.

F3 · price: Pursuant to the Option Repricing, the exercise price of the repriced options has been amended to reduce the exercise price to $104.13 per share, the thirty (30)-day trailing volume-weighted average price of the Common Stock on the Nasdaq Capital Market on the Repricing Date. However, if an optionholder exercises a repriced option before the end of a retention period of one year (which period may be shorter in certain circumstances), such optionholder will be required to pay the original exercise price per share of such repriced option. No other changes were made to the repriced options in connection with the Option Repricing, including with respect to the vesting schedules, expiration dates or number of shares underlying such repriced options.

F5 · derivative.exercise_date: 1/48th of the shares vest on a monthly basis from January 3, 2022, subject to Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan).

Read SEC document
December 11, 2025 Filed Dec 15, 2025 23:54 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 GrantStock Option (Right to Buy) · Derivative 933 Not disclosed Strike: $104.13 Not disclosed
Disclosure

SEC source: 0001533302-25-000009 · form4-12152025_111246.xml · derivative · entry 9

Gharib Samir M. · CIK 0001533302 · PRESIDENT AND CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 933

Underlying: Common Stock · 933 shares

Expires 2032-01-02

F2 · price: The transactions reported herein reflect a one-time stock option repricing (the "Option Repricing") effective on December 11, 2025 (the "Repricing Date"). The Option Repricing applies to options with exercise prices of $106.09 per share or greater held by employees and directors of the Issuer who remained in continuous service with the Company as of the Repricing Date.

F3 · price: Pursuant to the Option Repricing, the exercise price of the repriced options has been amended to reduce the exercise price to $104.13 per share, the thirty (30)-day trailing volume-weighted average price of the Common Stock on the Nasdaq Capital Market on the Repricing Date. However, if an optionholder exercises a repriced option before the end of a retention period of one year (which period may be shorter in certain circumstances), such optionholder will be required to pay the original exercise price per share of such repriced option. No other changes were made to the repriced options in connection with the Option Repricing, including with respect to the vesting schedules, expiration dates or number of shares underlying such repriced options.

F5 · derivative.exercise_date: 1/48th of the shares vest on a monthly basis from January 3, 2022, subject to Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan).

Read SEC document
December 11, 2025 Filed Dec 15, 2025 23:54 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 Disposition to issuerStock Option (Right to Buy) · Derivative 1,933 Not disclosed Strike: $186.00 Not disclosed
Disclosure

SEC source: 0001533302-25-000009 · form4-12152025_111246.xml · derivative · entry 8

Gharib Samir M. · CIK 0001533302 · PRESIDENT AND CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 1,933 shares

Expires 2031-12-15

F2 · price: The transactions reported herein reflect a one-time stock option repricing (the "Option Repricing") effective on December 11, 2025 (the "Repricing Date"). The Option Repricing applies to options with exercise prices of $106.09 per share or greater held by employees and directors of the Issuer who remained in continuous service with the Company as of the Repricing Date.

F3 · price: Pursuant to the Option Repricing, the exercise price of the repriced options has been amended to reduce the exercise price to $104.13 per share, the thirty (30)-day trailing volume-weighted average price of the Common Stock on the Nasdaq Capital Market on the Repricing Date. However, if an optionholder exercises a repriced option before the end of a retention period of one year (which period may be shorter in certain circumstances), such optionholder will be required to pay the original exercise price per share of such repriced option. No other changes were made to the repriced options in connection with the Option Repricing, including with respect to the vesting schedules, expiration dates or number of shares underlying such repriced options.

F4 · derivative.exercise_date: 1/48th of the shares vest on a monthly basis from December 16, 2021, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan).

Read SEC document
December 11, 2025 Filed Dec 15, 2025 23:54 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 GrantStock Option (Right to Buy) · Derivative 1,933 Not disclosed Strike: $104.13 Not disclosed
Disclosure

SEC source: 0001533302-25-000009 · form4-12152025_111246.xml · derivative · entry 7

Gharib Samir M. · CIK 0001533302 · PRESIDENT AND CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,933

Underlying: Common Stock · 1,933 shares

Expires 2031-12-15

F2 · price: The transactions reported herein reflect a one-time stock option repricing (the "Option Repricing") effective on December 11, 2025 (the "Repricing Date"). The Option Repricing applies to options with exercise prices of $106.09 per share or greater held by employees and directors of the Issuer who remained in continuous service with the Company as of the Repricing Date.

F3 · price: Pursuant to the Option Repricing, the exercise price of the repriced options has been amended to reduce the exercise price to $104.13 per share, the thirty (30)-day trailing volume-weighted average price of the Common Stock on the Nasdaq Capital Market on the Repricing Date. However, if an optionholder exercises a repriced option before the end of a retention period of one year (which period may be shorter in certain circumstances), such optionholder will be required to pay the original exercise price per share of such repriced option. No other changes were made to the repriced options in connection with the Option Repricing, including with respect to the vesting schedules, expiration dates or number of shares underlying such repriced options.

F4 · derivative.exercise_date: 1/48th of the shares vest on a monthly basis from December 16, 2021, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan).

Read SEC document
December 11, 2025 Filed Dec 15, 2025 23:54 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 Disposition to issuerStock Option (Right to Buy) · Derivative 733 Not disclosed Strike: $1,506.00 Not disclosed
Disclosure

SEC source: 0001533302-25-000009 · form4-12152025_111246.xml · derivative · entry 6

Gharib Samir M. · CIK 0001533302 · PRESIDENT AND CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 733 shares

Expires 2031-01-27

F2 · price: The transactions reported herein reflect a one-time stock option repricing (the "Option Repricing") effective on December 11, 2025 (the "Repricing Date"). The Option Repricing applies to options with exercise prices of $106.09 per share or greater held by employees and directors of the Issuer who remained in continuous service with the Company as of the Repricing Date.

F3 · price: Pursuant to the Option Repricing, the exercise price of the repriced options has been amended to reduce the exercise price to $104.13 per share, the thirty (30)-day trailing volume-weighted average price of the Common Stock on the Nasdaq Capital Market on the Repricing Date. However, if an optionholder exercises a repriced option before the end of a retention period of one year (which period may be shorter in certain circumstances), such optionholder will be required to pay the original exercise price per share of such repriced option. No other changes were made to the repriced options in connection with the Option Repricing, including with respect to the vesting schedules, expiration dates or number of shares underlying such repriced options.

F1 · derivative.exercise_date: The shares subject to the option are fully vested and exercisable.

Read SEC document
December 11, 2025 Filed Dec 15, 2025 23:54 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 GrantStock Option (Right to Buy) · Derivative 733 Not disclosed Strike: $104.13 Not disclosed
Disclosure

SEC source: 0001533302-25-000009 · form4-12152025_111246.xml · derivative · entry 5

Gharib Samir M. · CIK 0001533302 · PRESIDENT AND CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 733

Underlying: Common Stock · 733 shares

Expires 2031-01-27

F2 · price: The transactions reported herein reflect a one-time stock option repricing (the "Option Repricing") effective on December 11, 2025 (the "Repricing Date"). The Option Repricing applies to options with exercise prices of $106.09 per share or greater held by employees and directors of the Issuer who remained in continuous service with the Company as of the Repricing Date.

F3 · price: Pursuant to the Option Repricing, the exercise price of the repriced options has been amended to reduce the exercise price to $104.13 per share, the thirty (30)-day trailing volume-weighted average price of the Common Stock on the Nasdaq Capital Market on the Repricing Date. However, if an optionholder exercises a repriced option before the end of a retention period of one year (which period may be shorter in certain circumstances), such optionholder will be required to pay the original exercise price per share of such repriced option. No other changes were made to the repriced options in connection with the Option Repricing, including with respect to the vesting schedules, expiration dates or number of shares underlying such repriced options.

F1 · derivative.exercise_date: The shares subject to the option are fully vested and exercisable.

Read SEC document
December 11, 2025 Filed Dec 15, 2025 23:54 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 Disposition to issuerStock Option (Right to Buy) · Derivative 953 Not disclosed Strike: $230.25 Not disclosed
Disclosure

SEC source: 0001533302-25-000009 · form4-12152025_111246.xml · derivative · entry 4

Gharib Samir M. · CIK 0001533302 · PRESIDENT AND CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 953 shares

Expires 2030-08-06

F2 · price: The transactions reported herein reflect a one-time stock option repricing (the "Option Repricing") effective on December 11, 2025 (the "Repricing Date"). The Option Repricing applies to options with exercise prices of $106.09 per share or greater held by employees and directors of the Issuer who remained in continuous service with the Company as of the Repricing Date.

F3 · price: Pursuant to the Option Repricing, the exercise price of the repriced options has been amended to reduce the exercise price to $104.13 per share, the thirty (30)-day trailing volume-weighted average price of the Common Stock on the Nasdaq Capital Market on the Repricing Date. However, if an optionholder exercises a repriced option before the end of a retention period of one year (which period may be shorter in certain circumstances), such optionholder will be required to pay the original exercise price per share of such repriced option. No other changes were made to the repriced options in connection with the Option Repricing, including with respect to the vesting schedules, expiration dates or number of shares underlying such repriced options.

F1 · derivative.exercise_date: The shares subject to the option are fully vested and exercisable.

Read SEC document
December 11, 2025 Filed Dec 15, 2025 23:54 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 GrantStock Option (Right to Buy) · Derivative 953 Not disclosed Strike: $104.13 Not disclosed
Disclosure

SEC source: 0001533302-25-000009 · form4-12152025_111246.xml · derivative · entry 3

Gharib Samir M. · CIK 0001533302 · PRESIDENT AND CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 953

Underlying: Common Stock · 953 shares

Expires 2030-08-06

F2 · price: The transactions reported herein reflect a one-time stock option repricing (the "Option Repricing") effective on December 11, 2025 (the "Repricing Date"). The Option Repricing applies to options with exercise prices of $106.09 per share or greater held by employees and directors of the Issuer who remained in continuous service with the Company as of the Repricing Date.

F3 · price: Pursuant to the Option Repricing, the exercise price of the repriced options has been amended to reduce the exercise price to $104.13 per share, the thirty (30)-day trailing volume-weighted average price of the Common Stock on the Nasdaq Capital Market on the Repricing Date. However, if an optionholder exercises a repriced option before the end of a retention period of one year (which period may be shorter in certain circumstances), such optionholder will be required to pay the original exercise price per share of such repriced option. No other changes were made to the repriced options in connection with the Option Repricing, including with respect to the vesting schedules, expiration dates or number of shares underlying such repriced options.

F1 · derivative.exercise_date: The shares subject to the option are fully vested and exercisable.

Read SEC document
December 11, 2025 Filed Dec 15, 2025 23:54 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 Disposition to issuerStock Option (Right to Buy) · Derivative 1,579 Not disclosed Strike: $123.00 Not disclosed
Disclosure

SEC source: 0001533302-25-000009 · form4-12152025_111246.xml · derivative · entry 2

Gharib Samir M. · CIK 0001533302 · PRESIDENT AND CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 1,579 shares

Expires 2030-06-07

F2 · price: The transactions reported herein reflect a one-time stock option repricing (the "Option Repricing") effective on December 11, 2025 (the "Repricing Date"). The Option Repricing applies to options with exercise prices of $106.09 per share or greater held by employees and directors of the Issuer who remained in continuous service with the Company as of the Repricing Date.

F3 · price: Pursuant to the Option Repricing, the exercise price of the repriced options has been amended to reduce the exercise price to $104.13 per share, the thirty (30)-day trailing volume-weighted average price of the Common Stock on the Nasdaq Capital Market on the Repricing Date. However, if an optionholder exercises a repriced option before the end of a retention period of one year (which period may be shorter in certain circumstances), such optionholder will be required to pay the original exercise price per share of such repriced option. No other changes were made to the repriced options in connection with the Option Repricing, including with respect to the vesting schedules, expiration dates or number of shares underlying such repriced options.

F1 · derivative.exercise_date: The shares subject to the option are fully vested and exercisable.

Read SEC document
December 11, 2025 Filed Dec 15, 2025 23:54 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 GrantStock Option (Right to Buy) · Derivative 1,579 Not disclosed Strike: $104.13 Not disclosed
Disclosure

SEC source: 0001533302-25-000009 · form4-12152025_111246.xml · derivative · entry 1

Gharib Samir M. · CIK 0001533302 · PRESIDENT AND CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,579

Underlying: Common Stock · 1,579 shares

Expires 2030-06-07

F2 · price: The transactions reported herein reflect a one-time stock option repricing (the "Option Repricing") effective on December 11, 2025 (the "Repricing Date"). The Option Repricing applies to options with exercise prices of $106.09 per share or greater held by employees and directors of the Issuer who remained in continuous service with the Company as of the Repricing Date.

F3 · price: Pursuant to the Option Repricing, the exercise price of the repriced options has been amended to reduce the exercise price to $104.13 per share, the thirty (30)-day trailing volume-weighted average price of the Common Stock on the Nasdaq Capital Market on the Repricing Date. However, if an optionholder exercises a repriced option before the end of a retention period of one year (which period may be shorter in certain circumstances), such optionholder will be required to pay the original exercise price per share of such repriced option. No other changes were made to the repriced options in connection with the Option Repricing, including with respect to the vesting schedules, expiration dates or number of shares underlying such repriced options.

F1 · derivative.exercise_date: The shares subject to the option are fully vested and exercisable.

Read SEC document
December 10, 2025 Filed Dec 13, 2025 00:05 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 Exercise / conversionRestricted Stock Units · Derivative 514 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001533302-25-000007 · form4-12132025_121236.xml · derivative · entry 5

Gharib Samir M. · CIK 0001533302 · PRESIDENT AND CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,539

Underlying: Common Stock · 514 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each RSU represents a contingent right to receive one share of SPRB common stock.

F1 · derivative.exercise_date: On March 14, 2024, the Reporting Person was granted a total of 2,053 RSU's. Subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan) as of each such vesting date, 25% of the total number of RSUs vested on December 10, 2025, the first anniversary of the achievement of a specified clinical development objective. 25% of the total number of the RSUs will vest on each of the second, third and fourth anniversaries of such achievement. On December 10, 2025, 514 shares vested and 184 shares were withheld for taxes, resulting in a net issuance of 330 shares.

F1 · derivative.expiration_date: On March 14, 2024, the Reporting Person was granted a total of 2,053 RSU's. Subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan) as of each such vesting date, 25% of the total number of RSUs vested on December 10, 2025, the first anniversary of the achievement of a specified clinical development objective. 25% of the total number of the RSUs will vest on each of the second, third and fourth anniversaries of such achievement. On December 10, 2025, 514 shares vested and 184 shares were withheld for taxes, resulting in a net issuance of 330 shares.

Read SEC document
December 10, 2025 Filed Dec 13, 2025 00:05 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 Tax withholdingCommon Stock 184 $85.67 $15,763.28
Disclosure

SEC source: 0001533302-25-000007 · form4-12132025_121236.xml · nonDerivative · entry 2

Gharib Samir M. · CIK 0001533302 · PRESIDENT AND CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,396

F1 · shares: On March 14, 2024, the Reporting Person was granted a total of 2,053 RSU's. Subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan) as of each such vesting date, 25% of the total number of RSUs vested on December 10, 2025, the first anniversary of the achievement of a specified clinical development objective. 25% of the total number of the RSUs will vest on each of the second, third and fourth anniversaries of such achievement. On December 10, 2025, 514 shares vested and 184 shares were withheld for taxes, resulting in a net issuance of 330 shares.

Read SEC document
December 10, 2025 Filed Dec 13, 2025 00:05 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 Exercise / conversionCommon Stock 514 $0.00 $0.00
Disclosure

SEC source: 0001533302-25-000007 · form4-12132025_121236.xml · nonDerivative · entry 1

Gharib Samir M. · CIK 0001533302 · PRESIDENT AND CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,580

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: On March 14, 2024, the Reporting Person was granted a total of 2,053 RSU's. Subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan) as of each such vesting date, 25% of the total number of RSUs vested on December 10, 2025, the first anniversary of the achievement of a specified clinical development objective. 25% of the total number of the RSUs will vest on each of the second, third and fourth anniversaries of such achievement. On December 10, 2025, 514 shares vested and 184 shares were withheld for taxes, resulting in a net issuance of 330 shares.

F2 · price: Each RSU represents a contingent right to receive one share of SPRB common stock.

Read SEC document
October 20, 2025 Filed Oct 22, 2025 20:15 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 Exercise / conversionRestricted Stock Units · Derivative 2,053 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001533302-25-000004 · form4-10222025_041003.xml · derivative · entry 4

Gharib Samir M. · CIK 0001533302 · PRESIDENT AND CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 2,053 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each Restricted Stock Unit ("RSU") represents a contingent right to receive one share of SPRB common stock.

F1 · derivative.exercise_date: On March 14, 2024, the Reporting Person was granted 2,053 performance-based RSUs. On October 20, 2025, the Issuer's Board of Directors certified that certain specified performance goals were met and all of the RSUs vested. 661 shares were withheld for taxes, resulting in a net issuance of 1,392 shares.

F1 · derivative.expiration_date: On March 14, 2024, the Reporting Person was granted 2,053 performance-based RSUs. On October 20, 2025, the Issuer's Board of Directors certified that certain specified performance goals were met and all of the RSUs vested. 661 shares were withheld for taxes, resulting in a net issuance of 1,392 shares.

Read SEC document
October 20, 2025 Filed Oct 22, 2025 20:15 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 GrantRestricted Stock Units · Derivative 2,053 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001533302-25-000004 · form4-10222025_041003.xml · derivative · entry 3

Gharib Samir M. · CIK 0001533302 · PRESIDENT AND CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,053

Underlying: Common Stock · 2,053 shares

Expires not disclosed

F2 · derivative.exercise_price: Each Restricted Stock Unit ("RSU") represents a contingent right to receive one share of SPRB common stock.

F1 · derivative.exercise_date: On March 14, 2024, the Reporting Person was granted 2,053 performance-based RSUs. On October 20, 2025, the Issuer's Board of Directors certified that certain specified performance goals were met and all of the RSUs vested. 661 shares were withheld for taxes, resulting in a net issuance of 1,392 shares.

F1 · derivative.expiration_date: On March 14, 2024, the Reporting Person was granted 2,053 performance-based RSUs. On October 20, 2025, the Issuer's Board of Directors certified that certain specified performance goals were met and all of the RSUs vested. 661 shares were withheld for taxes, resulting in a net issuance of 1,392 shares.

Read SEC document
October 20, 2025 Filed Oct 22, 2025 20:15 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 Tax withholdingCommon Stock 661 $148.16 $97,933.76
Disclosure

SEC source: 0001533302-25-000004 · form4-10222025_041003.xml · nonDerivative · entry 2

Gharib Samir M. · CIK 0001533302 · PRESIDENT AND CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,066

F1 · shares: On March 14, 2024, the Reporting Person was granted 2,053 performance-based RSUs. On October 20, 2025, the Issuer's Board of Directors certified that certain specified performance goals were met and all of the RSUs vested. 661 shares were withheld for taxes, resulting in a net issuance of 1,392 shares.

Read SEC document
October 20, 2025 Filed Oct 22, 2025 20:15 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 Exercise / conversionCommon Stock 2,053 $0.00 $0.00
Disclosure

SEC source: 0001533302-25-000004 · form4-10222025_041003.xml · nonDerivative · entry 1

Gharib Samir M. · CIK 0001533302 · PRESIDENT AND CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,727

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: On March 14, 2024, the Reporting Person was granted 2,053 performance-based RSUs. On October 20, 2025, the Issuer's Board of Directors certified that certain specified performance goals were met and all of the RSUs vested. 661 shares were withheld for taxes, resulting in a net issuance of 1,392 shares.

F2 · price: Each Restricted Stock Unit ("RSU") represents a contingent right to receive one share of SPRB common stock.

Read SEC document
December 16, 2024 Filed Dec 21, 2024 01:28 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 Exercise / conversionRestricted Stock Units · Derivative 37,250 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001415889-24-030000 · form4-12212024_011255.xml · derivative · entry 9

Gharib Samir M. · CIK 0001533302 · PRESIDENT AND CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 74,500

Underlying: Common Stock · 37,250 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each RSU represents a contingent right to receive one share of SPRB common stock.

F3 · derivative.exercise_date: On December 5, 2022, the Reporting Person was granted 149,000 time-based restricted stock units ("RSUs"), subject to a 4-year vesting schedule, with 25% of the total number of RSUs vested on December 15, 2023 (the "Annual Vesting Date") and 25% of the total number of RSUs to vest in annual installments on each anniversary of the Annual Vesting Date thereafter, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On December 15, 2024, 37,250 RSUs vested, with 13,291 shares being withheld for taxes, resulting in a net issuance of 23,959 shares.

F3 · derivative.expiration_date: On December 5, 2022, the Reporting Person was granted 149,000 time-based restricted stock units ("RSUs"), subject to a 4-year vesting schedule, with 25% of the total number of RSUs vested on December 15, 2023 (the "Annual Vesting Date") and 25% of the total number of RSUs to vest in annual installments on each anniversary of the Annual Vesting Date thereafter, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On December 15, 2024, 37,250 RSUs vested, with 13,291 shares being withheld for taxes, resulting in a net issuance of 23,959 shares.

Read SEC document
December 16, 2024 Filed Dec 21, 2024 01:28 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 Exercise / conversionRestricted Stock Units · Derivative 38,500 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001415889-24-030000 · form4-12212024_011255.xml · derivative · entry 8

Gharib Samir M. · CIK 0001533302 · PRESIDENT AND CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 115,500

Underlying: Common Stock · 38,500 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each RSU represents a contingent right to receive one share of SPRB common stock.

F1 · derivative.exercise_date: On December 14, 2023, the Reporting Person was granted a total of 308,000 RSUs. 50% or 154,000 of the total RSUs are performance-based and since certain specified performance goals were met, they all vested on December 10, 2024. An additional 50% or 154,000 of the total RSUs are time-based. 25% of which vested on December 15, 2024, and in equal annual installments thereafter, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On December 15, 2024, 38,500 shares vested and 13,737 shares were withheld for taxes, resulting in a net issuance of 24,763 shares.

F1 · derivative.expiration_date: On December 14, 2023, the Reporting Person was granted a total of 308,000 RSUs. 50% or 154,000 of the total RSUs are performance-based and since certain specified performance goals were met, they all vested on December 10, 2024. An additional 50% or 154,000 of the total RSUs are time-based. 25% of which vested on December 15, 2024, and in equal annual installments thereafter, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On December 15, 2024, 38,500 shares vested and 13,737 shares were withheld for taxes, resulting in a net issuance of 24,763 shares.

F4 · balance_after: Represents the aggregate balance of time-based RSUs.

Read SEC document
December 16, 2024 Filed Dec 21, 2024 01:28 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 Tax withholdingCommon Stock 13,291 $0.39 $5,166.21
Disclosure

SEC source: 0001415889-24-030000 · form4-12212024_011255.xml · nonDerivative · entry 6

Gharib Samir M. · CIK 0001533302 · PRESIDENT AND CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 350,550

F3 · shares: On December 5, 2022, the Reporting Person was granted 149,000 time-based restricted stock units ("RSUs"), subject to a 4-year vesting schedule, with 25% of the total number of RSUs vested on December 15, 2023 (the "Annual Vesting Date") and 25% of the total number of RSUs to vest in annual installments on each anniversary of the Annual Vesting Date thereafter, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On December 15, 2024, 37,250 RSUs vested, with 13,291 shares being withheld for taxes, resulting in a net issuance of 23,959 shares.

Read SEC document
December 16, 2024 Filed Dec 21, 2024 01:28 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 Exercise / conversionCommon Stock 37,250 $0.00 $0.00
Disclosure

SEC source: 0001415889-24-030000 · form4-12212024_011255.xml · nonDerivative · entry 5

Gharib Samir M. · CIK 0001533302 · PRESIDENT AND CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 363,841

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · shares: On December 5, 2022, the Reporting Person was granted 149,000 time-based restricted stock units ("RSUs"), subject to a 4-year vesting schedule, with 25% of the total number of RSUs vested on December 15, 2023 (the "Annual Vesting Date") and 25% of the total number of RSUs to vest in annual installments on each anniversary of the Annual Vesting Date thereafter, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On December 15, 2024, 37,250 RSUs vested, with 13,291 shares being withheld for taxes, resulting in a net issuance of 23,959 shares.

F2 · price: Each RSU represents a contingent right to receive one share of SPRB common stock.

Read SEC document
December 16, 2024 Filed Dec 21, 2024 01:28 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 Tax withholdingCommon Stock 13,737 $0.39 $5,339.57
Disclosure

SEC source: 0001415889-24-030000 · form4-12212024_011255.xml · nonDerivative · entry 4

Gharib Samir M. · CIK 0001533302 · PRESIDENT AND CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 326,591

F1 · shares: On December 14, 2023, the Reporting Person was granted a total of 308,000 RSUs. 50% or 154,000 of the total RSUs are performance-based and since certain specified performance goals were met, they all vested on December 10, 2024. An additional 50% or 154,000 of the total RSUs are time-based. 25% of which vested on December 15, 2024, and in equal annual installments thereafter, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On December 15, 2024, 38,500 shares vested and 13,737 shares were withheld for taxes, resulting in a net issuance of 24,763 shares.

Read SEC document
December 16, 2024 Filed Dec 21, 2024 01:28 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 Exercise / conversionCommon Stock 38,500 $0.00 $0.00
Disclosure

SEC source: 0001415889-24-030000 · form4-12212024_011255.xml · nonDerivative · entry 3

Gharib Samir M. · CIK 0001533302 · PRESIDENT AND CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 340,328

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: On December 14, 2023, the Reporting Person was granted a total of 308,000 RSUs. 50% or 154,000 of the total RSUs are performance-based and since certain specified performance goals were met, they all vested on December 10, 2024. An additional 50% or 154,000 of the total RSUs are time-based. 25% of which vested on December 15, 2024, and in equal annual installments thereafter, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On December 15, 2024, 38,500 shares vested and 13,737 shares were withheld for taxes, resulting in a net issuance of 24,763 shares.

F2 · price: Each RSU represents a contingent right to receive one share of SPRB common stock.

Read SEC document
December 10, 2024 Filed Dec 21, 2024 01:28 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 Exercise / conversionRestricted Stock Units · Derivative 154,000 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001415889-24-030000 · form4-12212024_011255.xml · derivative · entry 7

Gharib Samir M. · CIK 0001533302 · PRESIDENT AND CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 154,000

Underlying: Common Stock · 154,000 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each RSU represents a contingent right to receive one share of SPRB common stock.

F1 · derivative.exercise_date: On December 14, 2023, the Reporting Person was granted a total of 308,000 RSUs. 50% or 154,000 of the total RSUs are performance-based and since certain specified performance goals were met, they all vested on December 10, 2024. An additional 50% or 154,000 of the total RSUs are time-based. 25% of which vested on December 15, 2024, and in equal annual installments thereafter, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On December 15, 2024, 38,500 shares vested and 13,737 shares were withheld for taxes, resulting in a net issuance of 24,763 shares.

F1 · derivative.expiration_date: On December 14, 2023, the Reporting Person was granted a total of 308,000 RSUs. 50% or 154,000 of the total RSUs are performance-based and since certain specified performance goals were met, they all vested on December 10, 2024. An additional 50% or 154,000 of the total RSUs are time-based. 25% of which vested on December 15, 2024, and in equal annual installments thereafter, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On December 15, 2024, 38,500 shares vested and 13,737 shares were withheld for taxes, resulting in a net issuance of 24,763 shares.

Read SEC document
December 10, 2024 Filed Dec 21, 2024 01:28 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 Tax withholdingCommon Stock 54,948 $0.54 $29,507.08
Disclosure

SEC source: 0001415889-24-030000 · form4-12212024_011255.xml · nonDerivative · entry 2

Gharib Samir M. · CIK 0001533302 · PRESIDENT AND CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 301,828

F1 · shares: On December 14, 2023, the Reporting Person was granted a total of 308,000 RSUs. 50% or 154,000 of the total RSUs are performance-based and since certain specified performance goals were met, they all vested on December 10, 2024. An additional 50% or 154,000 of the total RSUs are time-based. 25% of which vested on December 15, 2024, and in equal annual installments thereafter, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On December 15, 2024, 38,500 shares vested and 13,737 shares were withheld for taxes, resulting in a net issuance of 24,763 shares.

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December 10, 2024 Filed Dec 21, 2024 01:28 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 Exercise / conversionCommon Stock 154,000 $0.00 $0.00
Disclosure

SEC source: 0001415889-24-030000 · form4-12212024_011255.xml · nonDerivative · entry 1

Gharib Samir M. · CIK 0001533302 · PRESIDENT AND CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 356,776

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: On December 14, 2023, the Reporting Person was granted a total of 308,000 RSUs. 50% or 154,000 of the total RSUs are performance-based and since certain specified performance goals were met, they all vested on December 10, 2024. An additional 50% or 154,000 of the total RSUs are time-based. 25% of which vested on December 15, 2024, and in equal annual installments thereafter, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On December 15, 2024, 38,500 shares vested and 13,737 shares were withheld for taxes, resulting in a net issuance of 24,763 shares.

F2 · price: Each RSU represents a contingent right to receive one share of SPRB common stock.

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March 14, 2024 Filed Mar 18, 2024 20:29 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 GrantRestricted Stock Units · Derivative 154,000 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001415889-24-008270 · form4-03182024_080346.xml · derivative · entry 1

Gharib Samir M. · CIK 0001533302 · PRESIDENT AND CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 154,000

Underlying: Common Stock · 154,000 shares

Expires not disclosed

F1 · derivative.exercise_price: Each Restricted Stock Unit ("RSU") represents a contingent right to receive one share of SPRB common stock.

F2 · derivative.exercise_date: Subject to the Reporting Person's Continuous Service as of each such vesting date, 25% of the total number of RSUs vests upon each of the first, second, third and fourth anniversaries of the achievement of a specified clinical development objective.

F2 · derivative.expiration_date: Subject to the Reporting Person's Continuous Service as of each such vesting date, 25% of the total number of RSUs vests upon each of the first, second, third and fourth anniversaries of the achievement of a specified clinical development objective.

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December 29, 2023 Filed Jan 3, 2024 21:08 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 GrantCommon Stock 11,255 $0.98 $11,001.76
Disclosure

SEC source: 0001209191-24-000336 · doc4.xml · nonDerivative · entry 1

Gharib Samir M. · CIK 0001533302 · President & CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 202,776

F1 · shares: Shares acquired by the Reporting Person pursuant to the Issuer's 2020 Employee Stock Purchase Plan in a transaction that was exempt under both Rule 16b-3(d) and Rule 16b-3(c). The Reporting Person acquired the maximum shares allowable pursuant to Section 423 of the Internal Revenue Code.

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December 15, 2023 Filed Dec 19, 2023 01:16 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 Exercise / conversionRestricted Stock Units · Derivative 37,250 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001209191-23-059054 · doc4.xml · derivative · entry 7

Gharib Samir M. · CIK 0001533302 · President & CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 111,750

Underlying: Common Stock · 37,250 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each RSU represents a contingent right to receive one share of SPRB common stock.

F3 · shares: On December 5, 2022, the Reporting Person was granted 149,000 time-based RSUs, subject to a 4-year vesting schedule, with 25% of the total number of RSUs to vest on December 15, 2023 (the "Annual Vesting Date") and 25% of the total number of RSUs to vest in annual installments on each anniversary of the Annual Vesting Date thereafter, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On December 15, 2023, 37,250 RSUs vested, with 12,882 shares being withheld for taxes, resulting in a net issuance of 24,368 shares.

F3 · derivative.exercise_date: On December 5, 2022, the Reporting Person was granted 149,000 time-based RSUs, subject to a 4-year vesting schedule, with 25% of the total number of RSUs to vest on December 15, 2023 (the "Annual Vesting Date") and 25% of the total number of RSUs to vest in annual installments on each anniversary of the Annual Vesting Date thereafter, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On December 15, 2023, 37,250 RSUs vested, with 12,882 shares being withheld for taxes, resulting in a net issuance of 24,368 shares.

F3 · derivative.expiration_date: On December 5, 2022, the Reporting Person was granted 149,000 time-based RSUs, subject to a 4-year vesting schedule, with 25% of the total number of RSUs to vest on December 15, 2023 (the "Annual Vesting Date") and 25% of the total number of RSUs to vest in annual installments on each anniversary of the Annual Vesting Date thereafter, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On December 15, 2023, 37,250 RSUs vested, with 12,882 shares being withheld for taxes, resulting in a net issuance of 24,368 shares.

F7 · balance_after: Represents the aggregate balance of 111,750 time-based RSUs.

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December 15, 2023 Filed Dec 19, 2023 01:16 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 Exercise / conversionRestricted Stock Units · Derivative 75,000 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001209191-23-059054 · doc4.xml · derivative · entry 6

Gharib Samir M. · CIK 0001533302 · President & CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 75,000

Underlying: Common Stock · 75,000 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each RSU represents a contingent right to receive one share of SPRB common stock.

F1 · shares: On December 16, 2021, the Reporting Person was granted 150,000 time-based restricted stock units ("RSUs"), all of which were fully vested as of June 30, 2023. The Reporting Person was also granted 150,000 performance-based RSUs, which vest in two equal installments upon the achievement of specified performance goals, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On November 8, 2023, the Compensation Committee of the Issuer's Board of Directors certified the achievement of certain specified performance goals, resulting in the vesting of 75,000 performance-based RSUs effective December 15, 2023. On December 15, 2023, 23,213 shares were withheld for taxes, resulting in a net issuance of 51,787 shares.

F1 · derivative.exercise_date: On December 16, 2021, the Reporting Person was granted 150,000 time-based restricted stock units ("RSUs"), all of which were fully vested as of June 30, 2023. The Reporting Person was also granted 150,000 performance-based RSUs, which vest in two equal installments upon the achievement of specified performance goals, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On November 8, 2023, the Compensation Committee of the Issuer's Board of Directors certified the achievement of certain specified performance goals, resulting in the vesting of 75,000 performance-based RSUs effective December 15, 2023. On December 15, 2023, 23,213 shares were withheld for taxes, resulting in a net issuance of 51,787 shares.

F1 · derivative.expiration_date: On December 16, 2021, the Reporting Person was granted 150,000 time-based restricted stock units ("RSUs"), all of which were fully vested as of June 30, 2023. The Reporting Person was also granted 150,000 performance-based RSUs, which vest in two equal installments upon the achievement of specified performance goals, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On November 8, 2023, the Compensation Committee of the Issuer's Board of Directors certified the achievement of certain specified performance goals, resulting in the vesting of 75,000 performance-based RSUs effective December 15, 2023. On December 15, 2023, 23,213 shares were withheld for taxes, resulting in a net issuance of 51,787 shares.

F6 · balance_after: Represents the aggregate balance of 75,000 performance-based RSUs.

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December 15, 2023 Filed Dec 19, 2023 01:16 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 Tax withholdingCommon Stock 12,882 $1.66 $21,384.12
Disclosure

SEC source: 0001209191-23-059054 · doc4.xml · nonDerivative · entry 4

Gharib Samir M. · CIK 0001533302 · President & CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 191,521

F3 · shares: On December 5, 2022, the Reporting Person was granted 149,000 time-based RSUs, subject to a 4-year vesting schedule, with 25% of the total number of RSUs to vest on December 15, 2023 (the "Annual Vesting Date") and 25% of the total number of RSUs to vest in annual installments on each anniversary of the Annual Vesting Date thereafter, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On December 15, 2023, 37,250 RSUs vested, with 12,882 shares being withheld for taxes, resulting in a net issuance of 24,368 shares.

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December 15, 2023 Filed Dec 19, 2023 01:16 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 Exercise / conversionCommon Stock 37,250 $0.00 $0.00
Disclosure

SEC source: 0001209191-23-059054 · doc4.xml · nonDerivative · entry 3

Gharib Samir M. · CIK 0001533302 · President & CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 204,403

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · shares: On December 5, 2022, the Reporting Person was granted 149,000 time-based RSUs, subject to a 4-year vesting schedule, with 25% of the total number of RSUs to vest on December 15, 2023 (the "Annual Vesting Date") and 25% of the total number of RSUs to vest in annual installments on each anniversary of the Annual Vesting Date thereafter, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On December 15, 2023, 37,250 RSUs vested, with 12,882 shares being withheld for taxes, resulting in a net issuance of 24,368 shares.

F2 · price: Each RSU represents a contingent right to receive one share of SPRB common stock.

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December 15, 2023 Filed Dec 19, 2023 01:16 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 Tax withholdingCommon Stock 23,213 $1.66 $38,533.58
Disclosure

SEC source: 0001209191-23-059054 · doc4.xml · nonDerivative · entry 2

Gharib Samir M. · CIK 0001533302 · President & CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 167,153

F1 · shares: On December 16, 2021, the Reporting Person was granted 150,000 time-based restricted stock units ("RSUs"), all of which were fully vested as of June 30, 2023. The Reporting Person was also granted 150,000 performance-based RSUs, which vest in two equal installments upon the achievement of specified performance goals, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On November 8, 2023, the Compensation Committee of the Issuer's Board of Directors certified the achievement of certain specified performance goals, resulting in the vesting of 75,000 performance-based RSUs effective December 15, 2023. On December 15, 2023, 23,213 shares were withheld for taxes, resulting in a net issuance of 51,787 shares.

Read SEC document
December 15, 2023 Filed Dec 19, 2023 01:16 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 Exercise / conversionCommon Stock 75,000 $0.00 $0.00
Disclosure

SEC source: 0001209191-23-059054 · doc4.xml · nonDerivative · entry 1

Gharib Samir M. · CIK 0001533302 · President & CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 190,366

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: On December 16, 2021, the Reporting Person was granted 150,000 time-based restricted stock units ("RSUs"), all of which were fully vested as of June 30, 2023. The Reporting Person was also granted 150,000 performance-based RSUs, which vest in two equal installments upon the achievement of specified performance goals, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On November 8, 2023, the Compensation Committee of the Issuer's Board of Directors certified the achievement of certain specified performance goals, resulting in the vesting of 75,000 performance-based RSUs effective December 15, 2023. On December 15, 2023, 23,213 shares were withheld for taxes, resulting in a net issuance of 51,787 shares.

F2 · price: Each RSU represents a contingent right to receive one share of SPRB common stock.

Read SEC document
December 14, 2023 Filed Dec 19, 2023 01:16 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 GrantRestricted Stock Units · Derivative 308,000 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001209191-23-059054 · doc4.xml · derivative · entry 5

Gharib Samir M. · CIK 0001533302 · President & CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 308,000

Underlying: Common Stock · 308,000 shares

Expires not disclosed

F2 · derivative.exercise_price: Each RSU represents a contingent right to receive one share of SPRB common stock.

F4 · derivative.exercise_date: 154,000 of the RSUs shall vest as to 25% on December 15, 2024, and in equal annual installments thereafter, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan).

F5 · derivative.exercise_date: 154,000 of the RSUs shall vest upon the achievement of specified performance goals, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan).

F4 · derivative.expiration_date: 154,000 of the RSUs shall vest as to 25% on December 15, 2024, and in equal annual installments thereafter, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan).

F5 · derivative.expiration_date: 154,000 of the RSUs shall vest upon the achievement of specified performance goals, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan).

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November 08, 2023 Filed Nov 14, 2023 00:01 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 GrantRestricted Stock Units · Derivative 75,000 $0.00 $0.00
Disclosure

SEC source: 0001209191-23-055077 · doc4.xml · derivative · entry 1

Gharib Samir M. · CIK 0001533302 · President & CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 75,000

Underlying: Common Stock · 75,000 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit ("RSU") represents a contingent right to receive one share of SPRB common stock.

F2 · shares: On December 16, 2021, the Reporting Person was granted 150,000 time-based RSUs, all of which were fully vested as of June 30, 2023. The Reporting Person was also granted 150,000 performance-based RSUs, which vest in two equal installments upon the achievement of specified performance goals, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On November 8, 2023, the Compensation Committee of the Issuer's Board of Directors certified the achievement of certain specified performance goals, resulting in the vesting of 75,000 performance-based RSUs effective December 15, 2023.

F2 · derivative.exercise_date: On December 16, 2021, the Reporting Person was granted 150,000 time-based RSUs, all of which were fully vested as of June 30, 2023. The Reporting Person was also granted 150,000 performance-based RSUs, which vest in two equal installments upon the achievement of specified performance goals, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On November 8, 2023, the Compensation Committee of the Issuer's Board of Directors certified the achievement of certain specified performance goals, resulting in the vesting of 75,000 performance-based RSUs effective December 15, 2023.

F2 · derivative.expiration_date: On December 16, 2021, the Reporting Person was granted 150,000 time-based RSUs, all of which were fully vested as of June 30, 2023. The Reporting Person was also granted 150,000 performance-based RSUs, which vest in two equal installments upon the achievement of specified performance goals, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On November 8, 2023, the Compensation Committee of the Issuer's Board of Directors certified the achievement of certain specified performance goals, resulting in the vesting of 75,000 performance-based RSUs effective December 15, 2023.

F3 · balance_after: Represents the aggregate balance of 75,000 performance-based RSUs.

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June 30, 2023 Filed Jul 5, 2023 22:00 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 Exercise / conversionRestricted Stock Units · Derivative 75,000 $0.00 $0.00
Disclosure

SEC source: 0001209191-23-041250 · doc4.xml · derivative · entry 4

Gharib Samir M. · CIK 0001533302 · President & CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 150,000

Underlying: Common Stock · 75,000 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each restricted stock unit ("RSU") represents a contingent right to receive one share of SPRB common stock.

F4 · derivative.exercise_date: On December 16, 2021, the Reporting Person was granted 150,000 time-based RSUs. 25% of the RSUs vested on each of June 30, 2022 and December 31, 2022 and 50% vested on June 30, 2023, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). The Reporting Person was also granted 150,000 performance-based RSUs on December 16, 2021, which shall vest upon the achievement of specified performance goals.

F4 · derivative.expiration_date: On December 16, 2021, the Reporting Person was granted 150,000 time-based RSUs. 25% of the RSUs vested on each of June 30, 2022 and December 31, 2022 and 50% vested on June 30, 2023, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). The Reporting Person was also granted 150,000 performance-based RSUs on December 16, 2021, which shall vest upon the achievement of specified performance goals.

F5 · balance_after: Represents the aggregate balance of 150,000 performance-based RSUs.

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June 30, 2023 Filed Jul 5, 2023 22:00 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 Tax withholdingCommon Stock 25,936 $2.15 $55,762.40
Disclosure

SEC source: 0001209191-23-041250 · doc4.xml · nonDerivative · entry 3

Gharib Samir M. · CIK 0001533302 · President & CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 115,366

F3 · shares: Represents shares withheld by the Issuer to satisfy a tax obligation realized by the Reporting Person upon the vesting and settlement of RSUs.

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June 30, 2023 Filed Jul 5, 2023 22:00 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 Exercise / conversionCommon Stock 75,000 Not disclosed Not disclosed
Disclosure

SEC source: 0001209191-23-041250 · doc4.xml · nonDerivative · entry 2

Gharib Samir M. · CIK 0001533302 · President & CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 141,302

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · price: Each restricted stock unit ("RSU") represents a contingent right to receive one share of SPRB common stock.

Read SEC document
June 30, 2023 Filed Jul 5, 2023 22:00 UTC SPRUCE BIOSCIENCES, INC. SPRB · Entity 6471 GrantCommon Stock 10,484 $0.98 $10,248.11
Disclosure

SEC source: 0001209191-23-041250 · doc4.xml · nonDerivative · entry 1

Gharib Samir M. · CIK 0001533302 · President & CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 66,302

F1 · shares: Shares acquired by the Reporting Person pursuant to the Issuer's 2020 Employee Stock Purchase Plan in a transaction that was exempt under both Rule 16b-3(d) and Rule 16b-3(c).

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.