LAWLOR AUGUSTINE

SEC source: 0001104659-25-030808 · tm2511110-6_4seq1.xml · derivative · entry 4

LAWLOR AUGUSTINE · CIK 0001262327 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 22,500 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Each of the January 2022 RSUs represented a contingent right to receive one share of the Company's Common Stock.

F1 · kind: 22,500 Restricted Stock Units previously granted by the Company to the reporting person on January 31, 2022 (the "January 2022 RSUs") were settled on March 28, 2025 on a net issue basis such that, of the 22,500 shares of the Company's common stock underlying the January 22 RSUs, the Company issued to the reporting person on such settlement date only 14,703 of such shares and the Company withheld on such settlement date the remaining 7,797 of such shares in order to satisfy tax withholding obligations in connection with the settlement of the January 2022 RSUs. None of such 7,797 shares of the Company's common stock so withheld by the Company constituted sales of such shares by the reporting person.

F6 · derivative.exercise_date: The January 2022 RSUs became fully vested on January 31, 2025 but settlement thereof was deferred by the Compensation Committee of the Board of Directors of the Company until March 28, 2025 pursuant to, and in accordance with, the terms of the January 2022 RSUs, which terms provide that the Compensation Committee would have the authority to defer the settlement of the January 2022 RSUs to a date later than the vesting date of the January 2022 RSUs in the event that on such vesting date the reporting person were to be subject to, among other things, any limitation or restriction under the Company's insider trading policy that would not permit the reporting person to sell on such vesting date all of the shares of the Company's Common Stock underlying the January 2022 RSUs if the January 2022 RSUs were to be settled on such vesting date.

F7 · derivative.exercise_date: The Compensation Committee of the Board of Directors took action to defer settlement of the January 2022 RSUs so that such settlement would not occur on January 31, 2025, the vesting date thereof. The January 2022 RSUs were settled on March 28, 2025 on a net issue basis as further described on note (2) above.

F8 · derivative.expiration_date: The terms of the January 2022 RSUs provide that the January 2022 RSUs would automatically terminate and be forfeited upon termination of the reporting person's employment or other service relationship with the Company if such termination of employment or service relationship were to occur at any time prior to January 31, 2022, the vesting date of the January 2022 RSUs.

SEC source: 0001104659-25-030808 · tm2511110-6_4seq1.xml · nonDerivative · entry 2

LAWLOR AUGUSTINE · CIK 0001262327 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 19,789

F1 · kind: 22,500 Restricted Stock Units previously granted by the Company to the reporting person on January 31, 2022 (the "January 2022 RSUs") were settled on March 28, 2025 on a net issue basis such that, of the 22,500 shares of the Company's common stock underlying the January 22 RSUs, the Company issued to the reporting person on such settlement date only 14,703 of such shares and the Company withheld on such settlement date the remaining 7,797 of such shares in order to satisfy tax withholding obligations in connection with the settlement of the January 2022 RSUs. None of such 7,797 shares of the Company's common stock so withheld by the Company constituted sales of such shares by the reporting person.

F2 · balance_after: The share numbers reflected in Tables I and II have been adjusted to take into account a 10-for-1 reverse stock split of the Company's common stock that was effected on June 20, 2023.

SEC source: 0001104659-25-030808 · tm2511110-6_4seq1.xml · nonDerivative · entry 1

LAWLOR AUGUSTINE · CIK 0001262327 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,586

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: 22,500 Restricted Stock Units previously granted by the Company to the reporting person on January 31, 2022 (the "January 2022 RSUs") were settled on March 28, 2025 on a net issue basis such that, of the 22,500 shares of the Company's common stock underlying the January 22 RSUs, the Company issued to the reporting person on such settlement date only 14,703 of such shares and the Company withheld on such settlement date the remaining 7,797 of such shares in order to satisfy tax withholding obligations in connection with the settlement of the January 2022 RSUs. None of such 7,797 shares of the Company's common stock so withheld by the Company constituted sales of such shares by the reporting person.

F3 · price: Each of the January 2022 RSUs represented a contingent right to receive one share of the Company's Common Stock.

F2 · balance_after: The share numbers reflected in Tables I and II have been adjusted to take into account a 10-for-1 reverse stock split of the Company's common stock that was effected on June 20, 2023.

SEC source: 0001104659-24-119793 · tm2428586-2_4seq1.xml · derivative · entry 3

LAWLOR AUGUSTINE · CIK 0001262327 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 0

Underlying: Common Stock, $0.001 par value per share · 2,136 shares

Expires 2024-11-14

F1 · kind: On November 13, 2024, Nine Capital Partners, LLC ("Nine Capital Partners") exercised a warrant to purchase 2,136 shares of the Issuer's common stock at an exercise price of $2.82 per share. The reporting person is a managing member of Nine Capital Partners and may be deemed to have had beneficial ownership of such warrant exercised by Nine Capital Partners and to have beneficial ownership of the 2,136 shares of Common Stock purchased by Nine Capital Partners upon exercise of such warrant. The reporting person disclaims beneficial ownership of such warrant and of such shares of Common Stock, except to the extent of the reporting person's proportionate pecuniary interest in such warrant and such shares of Common Stock.

F1 · ownership.nature: On November 13, 2024, Nine Capital Partners, LLC ("Nine Capital Partners") exercised a warrant to purchase 2,136 shares of the Issuer's common stock at an exercise price of $2.82 per share. The reporting person is a managing member of Nine Capital Partners and may be deemed to have had beneficial ownership of such warrant exercised by Nine Capital Partners and to have beneficial ownership of the 2,136 shares of Common Stock purchased by Nine Capital Partners upon exercise of such warrant. The reporting person disclaims beneficial ownership of such warrant and of such shares of Common Stock, except to the extent of the reporting person's proportionate pecuniary interest in such warrant and such shares of Common Stock.

SEC source: 0001104659-24-119793 · tm2428586-2_4seq1.xml · nonDerivative · entry 1

LAWLOR AUGUSTINE · CIK 0001262327 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 678,456

F1 · kind: On November 13, 2024, Nine Capital Partners, LLC ("Nine Capital Partners") exercised a warrant to purchase 2,136 shares of the Issuer's common stock at an exercise price of $2.82 per share. The reporting person is a managing member of Nine Capital Partners and may be deemed to have had beneficial ownership of such warrant exercised by Nine Capital Partners and to have beneficial ownership of the 2,136 shares of Common Stock purchased by Nine Capital Partners upon exercise of such warrant. The reporting person disclaims beneficial ownership of such warrant and of such shares of Common Stock, except to the extent of the reporting person's proportionate pecuniary interest in such warrant and such shares of Common Stock.

F2 · balance_after: Includes (i) 2,136 shares of Common Stock held by Nine Capital Partners, (ii) 414,480 shares of Common Stock held by HealthCare Ventures IX, L.P. ("HCV IX"), and (iii) 261,840 shares of Common Stock held by the HCV VIII Trust ("HCV Trust"). See footnote (1) above for an explanation of the reporting person's beneficial ownership of the 2,136 shares of Common Stock held by Nine Capital Partners. The reporting person is a Managing Director of HCPIX LLC, which is the General Partner of HealthCare Partners IX, which is the General Partner of HCV IX and may be deemed to have beneficial ownership of the 414,480 shares of Common Stock held by HCV IX. The reporting person is the manager and a beneficiary of the HCV Trust and may be deemed to have beneficial ownership of the 261,840 shares of Common Stock held by the HCV Trust.

F3 · balance_after: The reporting person disclaims beneficial ownership of such shares of Common Stock held by each of Nine Capital Partners, HCV IX, and the HCV Trust, except to the extent of the reporting person's proportionate pecuniary interest in such shares of Common Stock.

F1 · ownership.nature: On November 13, 2024, Nine Capital Partners, LLC ("Nine Capital Partners") exercised a warrant to purchase 2,136 shares of the Issuer's common stock at an exercise price of $2.82 per share. The reporting person is a managing member of Nine Capital Partners and may be deemed to have had beneficial ownership of such warrant exercised by Nine Capital Partners and to have beneficial ownership of the 2,136 shares of Common Stock purchased by Nine Capital Partners upon exercise of such warrant. The reporting person disclaims beneficial ownership of such warrant and of such shares of Common Stock, except to the extent of the reporting person's proportionate pecuniary interest in such warrant and such shares of Common Stock.

F2 · ownership.nature: Includes (i) 2,136 shares of Common Stock held by Nine Capital Partners, (ii) 414,480 shares of Common Stock held by HealthCare Ventures IX, L.P. ("HCV IX"), and (iii) 261,840 shares of Common Stock held by the HCV VIII Trust ("HCV Trust"). See footnote (1) above for an explanation of the reporting person's beneficial ownership of the 2,136 shares of Common Stock held by Nine Capital Partners. The reporting person is a Managing Director of HCPIX LLC, which is the General Partner of HealthCare Partners IX, which is the General Partner of HCV IX and may be deemed to have beneficial ownership of the 414,480 shares of Common Stock held by HCV IX. The reporting person is the manager and a beneficiary of the HCV Trust and may be deemed to have beneficial ownership of the 261,840 shares of Common Stock held by the HCV Trust.

F3 · ownership.nature: The reporting person disclaims beneficial ownership of such shares of Common Stock held by each of Nine Capital Partners, HCV IX, and the HCV Trust, except to the extent of the reporting person's proportionate pecuniary interest in such shares of Common Stock.

SEC source: 0001104659-24-106335 · tm2425653-4_4seq1.xml · derivative · entry 1

LAWLOR AUGUSTINE · CIK 0001262327 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 85,000

Underlying: Common Stock · 85,000 shares

Expires 2034-10-02

F1 · derivative.exercise_date: The Option was granted pursuant to Leap's 2022 Equity Incentive Plan. By its terms, the Option shall vest and become exercisable for the shares underlying the Option in a series of 36 equal monthly installments for so long as the reporting person continues to be employed by or provides service to the Company, with the first of such monthly installments vesting on the one month anniversary of October 2, 2024.

SEC source: 0001104659-24-009022 · tm244775-3_4seq1.xml · derivative · entry 1

LAWLOR AUGUSTINE · CIK 0001262327 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 85,000

Underlying: Common Stock · 85,000 shares

Expires 2034-01-29

F1 · derivative.exercise_date: The Option was granted pursuant to Leap's 2016 Equity Incentive Plan. By its terms, the Option shall vest and become exercisable for the shares underlying the Option in a series of 36 equal monthly installments for so long as the reporting person continues to be employed by or provides service to the Company, with the first of such monthly installments vesting on the one month anniversary of January 29, 2024.

SEC source: 0001104659-24-008418 · tm244628-2_4seq1.xml · derivative · entry 4

LAWLOR AUGUSTINE · CIK 0001262327 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 5,000 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Restricted Stock Units convert into common stock on a one-for-one basis.

F5 · derivative.exercise_date: On January 26, 2021, the reporting person was granted 5,000 Restricted Stock Units, vesting on January 26, 2024 or upon a change of control, whichever is earlier, provided that the grantee continues to be employed by, or provides service to the Company from the grant date to the vesting date of the Restricted Stock Units. At such time as the Restricted Stock Units vest, one share of Common Stock shall be issued automatically in settlement of each Restricted Stock Unit.

F5 · derivative.expiration_date: On January 26, 2021, the reporting person was granted 5,000 Restricted Stock Units, vesting on January 26, 2024 or upon a change of control, whichever is earlier, provided that the grantee continues to be employed by, or provides service to the Company from the grant date to the vesting date of the Restricted Stock Units. At such time as the Restricted Stock Units vest, one share of Common Stock shall be issued automatically in settlement of each Restricted Stock Unit.

SEC source: 0001104659-24-008418 · tm244628-2_4seq1.xml · nonDerivative · entry 1

LAWLOR AUGUSTINE · CIK 0001262327 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,086

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Restricted Stock Units convert into common stock on a one-for-one basis.

F2 · balance_after: The share numbers reflected in Tables I and II have been adjusted to take into account a 10-for-1 reverse stock split of the Company's common stock that was effected on June 20, 2023.

SEC source: 0001140361-23-042365 · form4.xml · nonDerivative · entry 2

LAWLOR AUGUSTINE · CIK 0001262327 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · By The Lawlor Family Trust UAD 4-17-00

Disclosed balance after: 0

F1 · shares: On June 20, 2023, the Company's board of directors (the "Board") declared a dividend of one one-thousandth of a share of Series Y Preferred Stock, par value $0.001 per share (the "Preferred Stock"), for each outstanding share of common stock to common stockholders of record at 5:00 p.m. Eastern Time on June 30, 2023, in a transaction exempt from Section 16 under Rule 16a-9. The shares of Preferred Stock were distributed on June 30, 2023. As a result, the Reporting Person received the shares of Preferred Stock set forth above. The Preferred Stock was not convertible into, or exchangeable for, shares of any other class or series of stock or other securities of the Company.

F2 · shares: On August 31, 2023, the Company filed, as approved by the Board, a certificate of elimination with the Secretary of State of the State of Delaware pursuant to which the outstanding shares of the Preferred Stock were eliminated.

F2 · price: On August 31, 2023, the Company filed, as approved by the Board, a certificate of elimination with the Secretary of State of the State of Delaware pursuant to which the outstanding shares of the Preferred Stock were eliminated.

SEC source: 0001140361-23-042365 · form4.xml · nonDerivative · entry 1

LAWLOR AUGUSTINE · CIK 0001262327 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

F1 · shares: On June 20, 2023, the Company's board of directors (the "Board") declared a dividend of one one-thousandth of a share of Series Y Preferred Stock, par value $0.001 per share (the "Preferred Stock"), for each outstanding share of common stock to common stockholders of record at 5:00 p.m. Eastern Time on June 30, 2023, in a transaction exempt from Section 16 under Rule 16a-9. The shares of Preferred Stock were distributed on June 30, 2023. As a result, the Reporting Person received the shares of Preferred Stock set forth above. The Preferred Stock was not convertible into, or exchangeable for, shares of any other class or series of stock or other securities of the Company.

F2 · shares: On August 31, 2023, the Company filed, as approved by the Board, a certificate of elimination with the Secretary of State of the State of Delaware pursuant to which the outstanding shares of the Preferred Stock were eliminated.

F2 · price: On August 31, 2023, the Company filed, as approved by the Board, a certificate of elimination with the Secretary of State of the State of Delaware pursuant to which the outstanding shares of the Preferred Stock were eliminated.

SEC source: 0001104659-23-095365 · tm2324823-11_4seq1.xml · derivative · entry 1

LAWLOR AUGUSTINE · CIK 0001262327 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 70,000

Underlying: Common Stock · 70,000 shares

Expires 2033-08-23

F1 · derivative.exercise_date: The Option was granted pursuant to Leap's 2022 Equity Incentive Plan, as amended. By its terms, the Option shall vest and become exercisable for the shares underlying the Option in a series of 36 equal monthly installments for so long as the reporting person continues to be employed by or provides service to the Company, with the first of such monthly installments vesting on September 23, 2023 and an additional of such monthly installments vesting on the 23rd day of each calendar month thereafter.

SEC source: 0001062993-23-009600 · form4.xml · derivative · entry 3

LAWLOR AUGUSTINE · CIK 0001262327 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 103,719 shares

Expires not disclosed

F2 · derivative.exercise_price: Pursuant to the Merger Agreement, each unvested restricted stock unit became fully vested immediately prior to the effective time of the merger. Restricted stock units were then cancelled as of the effective time of the merger in exchange for the right to receive a cash payment equal to $20.00 multiplied by the number of restricted stock units, without interest and less any required withholding of taxes.

F2 · derivative.exercise_date: Pursuant to the Merger Agreement, each unvested restricted stock unit became fully vested immediately prior to the effective time of the merger. Restricted stock units were then cancelled as of the effective time of the merger in exchange for the right to receive a cash payment equal to $20.00 multiplied by the number of restricted stock units, without interest and less any required withholding of taxes.

F2 · derivative.expiration_date: Pursuant to the Merger Agreement, each unvested restricted stock unit became fully vested immediately prior to the effective time of the merger. Restricted stock units were then cancelled as of the effective time of the merger in exchange for the right to receive a cash payment equal to $20.00 multiplied by the number of restricted stock units, without interest and less any required withholding of taxes.

SEC source: 0001062993-23-009600 · form4.xml · nonDerivative · entry 2

LAWLOR AUGUSTINE · CIK 0001262327 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · By Lawlor Family Trust

Disclosed balance after: 0

F1 · shares: Pursuant to the Agreement and Plan of Merger by and among Cardiovascular Systems, Inc., a Delaware corporation, Abbott Laboratories, an Illinois corporation, and Cobra Acquisition Co., a Delaware corporation (the "Merger Agreement"), each share of common stock converted pursuant to the Merger Agreement into the right to receive $20.00 in cash per share, without interest and less any required withholding taxes.

SEC source: 0001062993-23-009600 · form4.xml · nonDerivative · entry 1

LAWLOR AUGUSTINE · CIK 0001262327 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

F1 · shares: Pursuant to the Agreement and Plan of Merger by and among Cardiovascular Systems, Inc., a Delaware corporation, Abbott Laboratories, an Illinois corporation, and Cobra Acquisition Co., a Delaware corporation (the "Merger Agreement"), each share of common stock converted pursuant to the Merger Agreement into the right to receive $20.00 in cash per share, without interest and less any required withholding taxes.

SEC source: 0001104659-23-041741 · tm2311741-1_4seq1.xml · derivative · entry 1

LAWLOR AUGUSTINE · CIK 0001262327 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 500,000

Underlying: Common Stock · 500,000 shares

Expires 2033-03-31

F1 · derivative.exercise_date: The Option was granted pursuant to Leap's 2016 Equity Incentive Plan. By its terms, the Option shall vest and become exercisable for the shares underlying the Option in a series of 36 equal monthly installments for so long as the reporting person continues to be employed by or provides service to the Company, with the first of such monthly installments vesting on the one month anniversary of March 31, 2023, the Vesting Start Date.

SEC source: 0001104659-22-097619 · tm2225099-8_4seq1.xml · derivative · entry 1

LAWLOR AUGUSTINE · CIK 0001262327 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 200,000

Underlying: Common Stock · 200,000 shares

Expires 2032-08-31

F1 · derivative.exercise_date: The Option was granted pursuant to Leap's 2022 Equity Incentive Plan and shall vest and become exercisable in a series of 36 equal monthly installments until the Option is fully vested, with the first such monthly installment vesting on the one month anniversary of September 1, 2022, the Vesting Start Date.

SEC source: 0001437749-22-019615 · rdgdoc.xml · derivative · entry 4

LAWLOR AUGUSTINE · CIK 0001262327 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,064

Underlying: Common Stock · 9,064 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted stock unit represents the right to receive a payment from the Company equal in value to the market price per share of Company common stock on the date of payment and shall be payable in cash or shares of Company common stock beginning six months following the termination of the reporting person's board membership; provided, however, that the restricted stock units vest in quarterly amounts of 2,266 shares on each of September 30, 2022, December 31, 2022, March 31, 2023 and June 30, 2023.

F2 · derivative.exercise_date: Each restricted stock unit represents the right to receive a payment from the Company equal in value to the market price per share of Company common stock on the date of payment and shall be payable in cash or shares of Company common stock beginning six months following the termination of the reporting person's board membership; provided, however, that the restricted stock units vest in quarterly amounts of 2,266 shares on each of September 30, 2022, December 31, 2022, March 31, 2023 and June 30, 2023.

F2 · derivative.expiration_date: Each restricted stock unit represents the right to receive a payment from the Company equal in value to the market price per share of Company common stock on the date of payment and shall be payable in cash or shares of Company common stock beginning six months following the termination of the reporting person's board membership; provided, however, that the restricted stock units vest in quarterly amounts of 2,266 shares on each of September 30, 2022, December 31, 2022, March 31, 2023 and June 30, 2023.

SEC source: 0001104659-22-011055 · tm225302-3_4seq1.xml · derivative · entry 1

LAWLOR AUGUSTINE · CIK 0001262327 · Chief Operating Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 225,000

Underlying: Common Stock · 225,000 shares

Expires not disclosed

F1 · derivative.exercise_price: The Restricted Stock Units were awarded pursuant to Leap's 2016 Equity Incentive Plan for no consideration. Restricted Stock Units will be settled in common stock.

F1 · price: The Restricted Stock Units were awarded pursuant to Leap's 2016 Equity Incentive Plan for no consideration. Restricted Stock Units will be settled in common stock.

F2 · derivative.exercise_date: The Restricted Stock Units will cliff vest and be settled after three years of continuous service or upon a change of control of Leap, whichever is earlier.

F2 · derivative.expiration_date: The Restricted Stock Units will cliff vest and be settled after three years of continuous service or upon a change of control of Leap, whichever is earlier.

SEC source: 0000914190-21-000411 · edgar.xml · nonDerivative · entry 1

LAWLOR AUGUSTINE · CIK 0001262327 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,022

F1 · shares: Represents fully vested restricted stock received at the election of the reporting person, in lieu of cash payment, as additional retainer for service as a director of the Company during fiscal year 2022.

SEC source: 0001209191-21-059429 · doc4.xml · nonDerivative · entry 1

LAWLOR AUGUSTINE · CIK 0001262327 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,573

F1 · shares: Represents shares of common stock received in lieu of fees.

SEC source: 0000914190-21-000245 · edgar.xml · derivative · entry 4

LAWLOR AUGUSTINE · CIK 0001262327 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,814

Underlying: Common Stock · 3,814 shares

Expires not disclosed

F4 · derivative.exercise_price: Each restricted stock unit represents the right to receive a payment from the Company equal in value to the market price per share of Company common stock on the date of payment and shall be payable in cash or shares of Company common stock beginning six months following the termination of the reporting person's board membership; provided, however, that the restricted stock units vest in quarterly amounts of 954 shares on each of September 30, 2021 and December 31, 2021 and as to 953 shares on each of March 31, 2022 and June 30, 2022.

F4 · derivative.exercise_date: Each restricted stock unit represents the right to receive a payment from the Company equal in value to the market price per share of Company common stock on the date of payment and shall be payable in cash or shares of Company common stock beginning six months following the termination of the reporting person's board membership; provided, however, that the restricted stock units vest in quarterly amounts of 954 shares on each of September 30, 2021 and December 31, 2021 and as to 953 shares on each of March 31, 2022 and June 30, 2022.

F4 · derivative.expiration_date: Each restricted stock unit represents the right to receive a payment from the Company equal in value to the market price per share of Company common stock on the date of payment and shall be payable in cash or shares of Company common stock beginning six months following the termination of the reporting person's board membership; provided, however, that the restricted stock units vest in quarterly amounts of 954 shares on each of September 30, 2021 and December 31, 2021 and as to 953 shares on each of March 31, 2022 and June 30, 2022.

SEC source: 0000914190-21-000245 · edgar.xml · nonDerivative · entry 1

LAWLOR AUGUSTINE · CIK 0001262327 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,800

F1 · shares: Represents restricted stock received at the election of the reporting person, in lieu of cash payment, as a retainer for service as a director of the Company during fiscal year 2022.

SEC source: 0001209191-21-044690 · doc4.xml · nonDerivative · entry 1

LAWLOR AUGUSTINE · CIK 0001262327 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,734

F1 · shares: Represents shares of common stock received in lieu of fees.

SEC source: 0001209191-21-044690 · doc4.xml · derivative · entry 3

LAWLOR AUGUSTINE · CIK 0001262327 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,000

Underlying: Common Stock · 14,000 shares

Expires 2031-06-09

F2 · derivative.exercise_date: 100% of the shares subject to the option will vest and become exercisable on June 9, 2022, the one-year anniversary of the grant date.

SEC source: 0001104659-21-074446 · tm2117938-3_4seq1.xml · derivative · entry 1

LAWLOR AUGUSTINE · CIK 0001262327 · Chief Operating Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,000

Underlying: Common Stock · 30,000 shares

Expires 2031-05-25

F1 · derivative.exercise_date: The Option was granted pursuant to Leap's 2016 Equity Incentive Plan and shall vest and become exercisable in a series of 36 equal monthly installments until the Option is fully vested, with the first such monthly installment vesting on the one month anniversary of May 26, 2021, the Vesting Start Date.

SEC source: 0001209191-21-025032 · doc4.xml · nonDerivative · entry 1

LAWLOR AUGUSTINE · CIK 0001262327 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,192

F1 · shares: Represents shares of common stock received in lieu of fees.

SEC source: 0001104659-21-021299 · tm216410-5_4seq1.xml · derivative · entry 2

LAWLOR AUGUSTINE · CIK 0001262327 · Chief Operating Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 11,544

Underlying: Common Stock, $0.001 par value per share · 11,544 shares

Expires 2026-02-05

F1 · kind: On February 9, 2020, HealthCare Ventures IX, L.P. ("HCVIX") transferred, for no consideration, all 571,428 warrants to purchase common stock it held (the "Transfer") to the limited partners of HCVIX on a pro rata basis. The term of HCVIX expired on December 31, 2020, at which time HCVIX entered into liquidation. The process of liquidating HCVIX, including the distribution of marketable and non-marketable securities, has commenced in 2021, and HealthCare Partners IX, L.P. ("HCPIX"), the General Partner of HCVIX, as liquidator, will use its best efforts to complete the orderly liquidation of HCVIX.

F3 · price: The warrants were acquired in connection with the purchase of an equal number of shares of common stock by HCVIX on February 5, 2019 for $1.75 per share. Each such purchased share of common stock was issued with a warrant to purchase one share of common stock. HCVIX will continue to hold 4,144,804 shares of common stock following the Transfer.

F4 · ownership.nature: These warrants were acquired by Nine Capital Partners, LLC ("Nine Capital Partners"), a limited partner of HCVIX, in connection with the Transfer. The reporting person is a member of Nine Capital Partners and may be deemed to indirectly beneficially own and share voting and dispositive power with respect to all securities held by Nine Capital Partners. The reporting person disclaims beneficial ownership of the warrants except to the extent of his proportionate pecuniary interest therein.

SEC source: 0001104659-21-021299 · tm216410-5_4seq1.xml · derivative · entry 1

LAWLOR AUGUSTINE · CIK 0001262327 · Chief Operating Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 0

Underlying: Common Stock, $0.001 par value per share · 571,428 shares

Expires 2026-02-05

F1 · kind: On February 9, 2020, HealthCare Ventures IX, L.P. ("HCVIX") transferred, for no consideration, all 571,428 warrants to purchase common stock it held (the "Transfer") to the limited partners of HCVIX on a pro rata basis. The term of HCVIX expired on December 31, 2020, at which time HCVIX entered into liquidation. The process of liquidating HCVIX, including the distribution of marketable and non-marketable securities, has commenced in 2021, and HealthCare Partners IX, L.P. ("HCPIX"), the General Partner of HCVIX, as liquidator, will use its best efforts to complete the orderly liquidation of HCVIX.

F2 · kind: These warrants were owned directly by HCVIX. Christopher K. Mirabelli, Douglas E. Onsi and Augustine Lawlor (collectively, the "HCVIX Directors") are the Managing Directors of HealthCare Partners IX, LLC ("HCPIX LLC"), which is the General Partner of HCPIX, which is the General Partner of HCVIX. Each of the HCVIX Directors, HCPIX LLC and HCPIX indirectly beneficially owns and shares voting and dispositive power with respect to all of the securities owned by HCVIX, and each disclaimed beneficial ownership of the warrants except to the extent of his or its proportionate pecuniary interest therein.

F3 · price: The warrants were acquired in connection with the purchase of an equal number of shares of common stock by HCVIX on February 5, 2019 for $1.75 per share. Each such purchased share of common stock was issued with a warrant to purchase one share of common stock. HCVIX will continue to hold 4,144,804 shares of common stock following the Transfer.

F2 · ownership.nature: These warrants were owned directly by HCVIX. Christopher K. Mirabelli, Douglas E. Onsi and Augustine Lawlor (collectively, the "HCVIX Directors") are the Managing Directors of HealthCare Partners IX, LLC ("HCPIX LLC"), which is the General Partner of HCPIX, which is the General Partner of HCVIX. Each of the HCVIX Directors, HCPIX LLC and HCPIX indirectly beneficially owns and shares voting and dispositive power with respect to all of the securities owned by HCVIX, and each disclaimed beneficial ownership of the warrants except to the extent of his or its proportionate pecuniary interest therein.

SEC source: 0001104659-21-008992 · tm214605-3_4seq1.xml · derivative · entry 2

LAWLOR AUGUSTINE · CIK 0001262327 · Chief Operating Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 50,000

Underlying: Common Stock · 50,000 shares

Expires not disclosed

F2 · derivative.exercise_price: The Restricted Stock Units were awarded pursuant to Leap's 2016 Equity Incentive Plan for no consideration. Restricted Stock Units will be settled in common stock.

F2 · price: The Restricted Stock Units were awarded pursuant to Leap's 2016 Equity Incentive Plan for no consideration. Restricted Stock Units will be settled in common stock.

F3 · derivative.exercise_date: The Restricted Stock Units will cliff vest and be settled after three years of continuous service or upon a change of control of Leap, whichever is earlier.

F3 · derivative.expiration_date: The Restricted Stock Units will cliff vest and be settled after three years of continuous service or upon a change of control of Leap, whichever is earlier.

SEC source: 0001104659-21-008992 · tm214605-3_4seq1.xml · derivative · entry 1

LAWLOR AUGUSTINE · CIK 0001262327 · Chief Operating Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 150,000

Underlying: Common Stock · 150,000 shares

Expires 2031-01-25

F1 · derivative.exercise_date: The Option was granted pursuant to Leap's 2016 Equity Incentive Plan and shall vest and become exercisable in a series of 36 equal monthly installments until the Option is fully vested, with the first such monthly installment vesting on the one month anniversary of January 26, 2021, the Vesting Start Date.

SEC source: 0001209191-21-002162 · doc4.xml · nonDerivative · entry 1

LAWLOR AUGUSTINE · CIK 0001262327 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,431

F1 · shares: Represents shares of common stock received in lieu of fees.

SEC source: 0001209191-20-053123 · doc4.xml · nonDerivative · entry 1

LAWLOR AUGUSTINE · CIK 0001262327 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,014

F1 · shares: Represents shares of common stock received in lieu of fees.

SEC source: 0001104659-20-094201 · a4.xml · derivative · entry 1

LAWLOR AUGUSTINE · CIK 0001262327 · Chief Operating Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 75,000

Underlying: Common Stock · 75,000 shares

Expires 2030-08-09

F1 · derivative.exercise_date: The Option was granted pursuant to Leap's 2016 Equity Incentive Plan and shall vest and become exercisable in a series of 36 equal monthly installments until the Option is fully vested, with the first such monthly installment vesting on the one month anniversary of August 10, 2020, the Vesting Start Date.

SEC source: 0000914190-20-000264 · edgar.xml · derivative · entry 3

LAWLOR AUGUSTINE · CIK 0001262327 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,661

Underlying: Common Stock · 4,661 shares

Expires not disclosed

F3 · derivative.exercise_price: Each restricted stock unit represents the right to receive a payment from the Company equal in value to the market price per share of Company common stock on the date of payment and shall be payable in cash or shares of Company common stock beginning six months following the termination of the reporting person's board membership; provided, however, that the restricted stock units vest in quarterly amounts of 1,166 shares on September 30, 2020 and 1,165 shares on each of December 31, 2020, March 31, 2021 and June 30, 2021.

F3 · derivative.exercise_date: Each restricted stock unit represents the right to receive a payment from the Company equal in value to the market price per share of Company common stock on the date of payment and shall be payable in cash or shares of Company common stock beginning six months following the termination of the reporting person's board membership; provided, however, that the restricted stock units vest in quarterly amounts of 1,166 shares on September 30, 2020 and 1,165 shares on each of December 31, 2020, March 31, 2021 and June 30, 2021.

F3 · derivative.expiration_date: Each restricted stock unit represents the right to receive a payment from the Company equal in value to the market price per share of Company common stock on the date of payment and shall be payable in cash or shares of Company common stock beginning six months following the termination of the reporting person's board membership; provided, however, that the restricted stock units vest in quarterly amounts of 1,166 shares on September 30, 2020 and 1,165 shares on each of December 31, 2020, March 31, 2021 and June 30, 2021.

SEC source: 0000914190-20-000264 · edgar.xml · nonDerivative · entry 1

LAWLOR AUGUSTINE · CIK 0001262327 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,408

F1 · shares: Represents restricted stock received at the election of the reporting person, in lieu of cash payment, as a retainer for service as a director of the Company during fiscal year 2021.

SEC source: 0001209191-20-040391 · doc4.xml · nonDerivative · entry 1

LAWLOR AUGUSTINE · CIK 0001262327 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,215

F1 · shares: Represents shares of common stock received in lieu of fees.

SEC source: 0001209191-20-036313 · doc4.xml · derivative · entry 1

LAWLOR AUGUSTINE · CIK 0001262327 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,000

Underlying: Common Stock · 5,000 shares

Expires 2030-06-11

F1 · derivative.exercise_date: The option shall vest monthly over a period of 12 months commencing June 11, 2020.

SEC source: 0001104659-20-046072 · a4.xml · derivative · entry 1

LAWLOR AUGUSTINE · CIK 0001262327 · Chief Operating Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 50,000

Underlying: Common Stock · 50,000 shares

Expires 2030-04-09

F1 · derivative.exercise_date: The Option was granted pursuant to Leap's 2016 Equity Incentive Plan and shall vest and become exercisable in a series of 36 equal monthly installments until the Option is fully vested, with the first such monthly installment vesting on the one-month anniversary of April 9, 2020, the Vesting Start Date.

SEC source: 0001209191-20-023187 · doc4.xml · nonDerivative · entry 1

LAWLOR AUGUSTINE · CIK 0001262327 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,542

F1 · shares: Represents shares of common stock received in lieu of fees.

SEC source: 0001209191-20-012454 · doc4.xml · nonDerivative · entry 1

LAWLOR AUGUSTINE · CIK 0001262327 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By HealthCare Ventures VIII, L.P.

Disclosed balance after: 0

F1 · price: Represents the weighted average sales price per share. The shares sold at prices ranging from $6.10 to $6.22 per share. Full information regarding the number of shares sold at each price shall be provided upon request to the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer.

F2 · ownership.nature: HealthCare Ventures VIII, L.P. ("HCVVIII") is the registered owner of the securities. The Reporting Person is a managing director of HealthCare Partners VIII, LLC ("HCPVIII LLC"), the General Partner of HealthCare Partners VIII, L.P. ("HCPVIII"). HCPVIII is the General Partner of HCVVIII. The Reporting Person shares voting and investment power over the shares held by HCVVIII with each of Christopher Mirabelli, James Cavanaugh, John Littlechild and Harold Werner as managing directors of HCPVIII LLC. The Reporting Person disclaims beneficial ownership of those securities in which he does not have a pecuniary interest and this report shall not be deemed an admission that he is the beneficial owner of these securities for purposes of Section 16, except to the extent of his pecuniary interest therein.

SEC source: 0001209191-20-000340 · doc4.xml · nonDerivative · entry 1

LAWLOR AUGUSTINE · CIK 0001262327 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,608

F1 · shares: Represents shares of stock received in lieu of fees.

SEC source: 0001209191-19-051620 · doc4.xml · nonDerivative · entry 1

LAWLOR AUGUSTINE · CIK 0001262327 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,442

F1 · shares: Represents shares of stock received in lieu of fees.

SEC source: 0000914190-19-000289 · edgar.xml · derivative · entry 3

LAWLOR AUGUSTINE · CIK 0001262327 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,088

Underlying: Common Stock · 3,088 shares

Expires not disclosed

F3 · derivative.exercise_price: Each restricted stock unit represents the right to receive a payment from the Company equal in value to the market price per share of Company common stock on the date of payment and shall be payable in cash or shares of Company common stock beginning six months following the termination of the reporting person's board membership; provided, however, that the restricted stock units vest in quarterly amounts of 772 shares on each of September 30, 2019, December 31, 2019, March 31, 2020 and June 30, 2020.

F3 · derivative.exercise_date: Each restricted stock unit represents the right to receive a payment from the Company equal in value to the market price per share of Company common stock on the date of payment and shall be payable in cash or shares of Company common stock beginning six months following the termination of the reporting person's board membership; provided, however, that the restricted stock units vest in quarterly amounts of 772 shares on each of September 30, 2019, December 31, 2019, March 31, 2020 and June 30, 2020.

F3 · derivative.expiration_date: Each restricted stock unit represents the right to receive a payment from the Company equal in value to the market price per share of Company common stock on the date of payment and shall be payable in cash or shares of Company common stock beginning six months following the termination of the reporting person's board membership; provided, however, that the restricted stock units vest in quarterly amounts of 772 shares on each of September 30, 2019, December 31, 2019, March 31, 2020 and June 30, 2020.

SEC source: 0000914190-19-000289 · edgar.xml · nonDerivative · entry 1

LAWLOR AUGUSTINE · CIK 0001262327 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,318

F1 · shares: Represents restricted stock received at the election of the reporting person, in lieu of cash payment, as a retainer for service as a director of the Company during fiscal year 2020.

SEC source: 0001209191-19-040360 · doc4.xml · nonDerivative · entry 1

LAWLOR AUGUSTINE · CIK 0001262327 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,051

F1 · shares: Represents shares of stock received in lieu of fees.

SEC source: 0001209191-19-037572 · doc4.xml · derivative · entry 1

LAWLOR AUGUSTINE · CIK 0001262327 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,000

Underlying: Common Stock · 5,000 shares

Expires 2029-06-13

F1 · derivative.exercise_date: The option shall vest monthly over a period of 12 months commencing June 13, 2019.

SEC source: 0001104659-19-035079 · a4.xml · derivative · entry 1

LAWLOR AUGUSTINE · CIK 0001262327 · Chief Operating Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 200,000

Underlying: Common Stock · 200,000 shares

Expires 2029-06-10

F1 · derivative.exercise_date: The Option was granted pursuant to Leap's 2016 Equity Incentive Plan and shall vest and become exercisable in a series of 36 equal monthly installments until the Option is fully vested, with the first such monthly installment vesting on the one-month anniversary of June 11, 2019, the Vesting Start Date.

SEC source: 0001209191-19-022537 · doc4.xml · nonDerivative · entry 1

LAWLOR AUGUSTINE · CIK 0001262327 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,146

F1 · shares: Represents shares of stock received in lieu of fees.

SEC source: 0001104659-19-005837 · a4.xml · derivative · entry 4

LAWLOR AUGUSTINE · CIK 0001262327 · Chief Operating Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 592,797

Underlying: Common Stock, $0.001 par value per share · 571,428 shares

Expires 2026-02-05

F4 · price: The reported securities were included with the 571,428 shares of common stock purchased by HealthCare Ventures IX, L.P. for $1.75 per share. Each such purchased share of common stock was issued with a warrant to purchase one share of common stock.

F1 · ownership.nature: The shares are owned directly by HealthCare Ventures IX, L.P. Christopher K. Mirabelli, Douglas E. Onsi and Augustine Lawlor (collectively, the "HCVIX Directors") are the Managing Directors of HealthCare Partners IX, LLC ("HCPIX LLC"), which is the General Partner of HealthCare Partners IX, L.P. ("HCPIX"), which is the General Partner of HealthCare Ventures IX, L.P. Each of the HCVIX Directors, HCPIX LLC and HCPIX beneficially own and share voting and dispositive power with respect to all of the securities owned by HealthCare Ventures IX, L.P. Augustine Lawlor disclaims beneficial ownership of these shares except to the extent of his proportionate pecuniary interest in these securities.