Heino Mary Anne

SEC source: 0000899243-23-007259 · doc4.xml · nonDerivative · entry 4

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 741,650

F3 · kind: The Company requires certain senior executives to cover tax liabilities resulting from the vesting of their equity awards pursuant to sell-to-cover transactions in compliance with Rule 10b5-1. The transaction reported in this Form 4 was effected in compliance with Rule 10b5-1 to satisfy withholding tax liabilities of the Reporting Person associated with the vesting of restricted stock previously granted and reported on a previously filed Form 4.

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $73.14 to $73.99, inclusive. The reporting person undertakes to provide to LNTH any security holder of LNTH or the staff of the SEC, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (5) to this Form 4.

SEC source: 0000899243-23-007259 · doc4.xml · nonDerivative · entry 3

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 759,047

F3 · kind: The Company requires certain senior executives to cover tax liabilities resulting from the vesting of their equity awards pursuant to sell-to-cover transactions in compliance with Rule 10b5-1. The transaction reported in this Form 4 was effected in compliance with Rule 10b5-1 to satisfy withholding tax liabilities of the Reporting Person associated with the vesting of restricted stock previously granted and reported on a previously filed Form 4.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $72.14 to $73.135, inclusive. The reporting person undertakes to provide to Lantheus Holdings, Inc. ("LNTH") any security holder of LNTH or the staff of the Securities and Exchange Commission ("SEC"), upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (4) to this Form 4.

SEC source: 0000899243-23-007259 · doc4.xml · nonDerivative · entry 2

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 823,705

F2 · kind: The transaction reported in this Form 4 reflects additional shares of common stock issued by the Company to the reporting person upon the vesting of relative Total Shareholder Return PSUs that were previously granted and included in the Form 4 filed on March 5, 2020. The number of shares reported in the Form 4 reflected 100% of the target number of shares underlying the PSUs. The number of shares that actually vested under the PSUs equaled 200% of the target number of shares. Accordingly, the number of shares reported in this Form 4 reflects the difference between the number of shares that actually vested under the PSUs and the target number of shares originally included in the Form 4.

SEC source: 0000899243-23-007259 · doc4.xml · derivative · entry 6

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 44,696

Underlying: Common Stock · 44,696 shares

Expires 2033-03-02

F7 · derivative.exercise_date: The option vests in three equal annual installments beginning on March 2, 2024.

SEC source: 0000899243-23-007259 · doc4.xml · nonDerivative · entry 1

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 749,219

F1 · kind: Consists of 25,562 restricted stock units that vest in equal installments over a three-year period and 51,124 Total Shareholder Return performance-based restricted stock units ("PSUs") that cliff vest following a three-year performance period. The amount of PSUs included in this Report reflects the target award, however the ultimate award size can range from 0% to 200% of the target based on the actual performance achieved at the end of the performance period.

SEC source: 0000899243-22-035521 · doc4.xml · nonDerivative · entry 4

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 672,533

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 11, 2022.

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $58.38 to $58.97, inclusive. The reporting person undertakes to provide to LNTH, any security holder of LNTH, or the staff of the SEC, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (5) to this Form 4.

SEC source: 0000899243-22-035521 · doc4.xml · nonDerivative · entry 3

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 674,049

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 11, 2022.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $57.36 to $58.35, inclusive. The reporting person undertakes to provide to LNTH, any security holder of LNTH, or the staff of the SEC, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (4) to this Form 4.

SEC source: 0000899243-22-035521 · doc4.xml · nonDerivative · entry 2

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 678,933

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 11, 2022.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $56.36 to $57.31, inclusive. The reporting person undertakes to provide to LNTH, any security holder of LNTH, or the staff of the SEC, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (3) to this Form 4.

SEC source: 0000899243-22-035521 · doc4.xml · nonDerivative · entry 1

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 683,683

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 11, 2022.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $55.36 to $56.33, inclusive. The reporting person undertakes to provide to Lantheus Holdings, Inc., ("LNTH"), any security holder of LNTH, or the staff of the Securities and Exchange Commission ("SEC"), upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (2) to this Form 4.

SEC source: 0000899243-22-028258 · doc4.xml · nonDerivative · entry 3

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 685,683

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 11, 2022.

SEC source: 0000899243-22-028258 · doc4.xml · nonDerivative · entry 2

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 685,883

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 11, 2022.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $79.81 to $80.25, inclusive. The reporting person undertakes to provide to LNTH, any security holder of LNTH, or the staff of the SEC, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (3) to this Form 4.

SEC source: 0000899243-22-028258 · doc4.xml · nonDerivative · entry 1

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 690,143

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 11, 2022.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $78.81 to $79.745, inclusive. The reporting person undertakes to provide to Lantheus Holdings, Inc., ("LNTH"), any security holder of LNTH, or the staff of the Securities and Exchange Commission ("SEC"), upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (2) to this Form 4.

SEC source: 0000899243-22-017651 · doc4.xml · nonDerivative · entry 6

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 695,115

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 11, 2022.

F7 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $63.25 to $63.90, inclusive. The reporting person undertakes to provide to LNTH any security holder of LNTH or the staff of the SEC, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (7) to this Form 4.

SEC source: 0000899243-22-017651 · doc4.xml · nonDerivative · entry 5

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 696,115

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 11, 2022.

F6 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $62.21 to $63.12, inclusive. The reporting person undertakes to provide to LNTH any security holder of LNTH or the staff of the SEC, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (6) to this Form 4.

SEC source: 0000899243-22-017651 · doc4.xml · nonDerivative · entry 4

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 698,215

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 11, 2022.

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $61.32 to $61.88, inclusive. The reporting person undertakes to provide to LNTH any security holder of LNTH or the staff of the SEC, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (5) to this Form 4.

SEC source: 0000899243-22-017651 · doc4.xml · nonDerivative · entry 3

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 701,615

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 11, 2022.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $60.16 to $60.935, inclusive. The reporting person undertakes to provide to LNTH any security holder of LNTH or the staff of the SEC, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (4) to this Form 4.

SEC source: 0000899243-22-017651 · doc4.xml · nonDerivative · entry 2

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 704,593

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 11, 2022.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $59.14 to $60.125, inclusive. The reporting person undertakes to provide to LNTH any security holder of LNTH or the staff of the SEC, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (3) to this Form 4.

SEC source: 0000899243-22-017651 · doc4.xml · nonDerivative · entry 1

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 706,766

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 11, 2022.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $58.11 to $58.945, inclusive. The reporting person undertakes to provide to Lantheus Holdings, Inc., ("LNTH") any security holder of LNTH or the staff of the Securities and Exchange Commission ("SEC"), upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (2) to this Form 4.

SEC source: 0000899243-22-009811 · doc4.xml · nonDerivative · entry 5

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 707,391

F2 · kind: The Company requires certain senior executives to cover tax liabilities resulting from the vesting of their equity awards pursuant to sell-to-cover transactions in compliance with Rule 10b5-1. The transaction reported in this Form 4 was effected in compliance with Rule 10b5-1 to satisfy withholding tax liabilities of the Reporting Person associated with the vesting of restricted stock previously granted and reported on a previously filed Form 4.

F6 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $50.69 to $51.62, inclusive. The reporting person undertakes to provide to LNTH any security holder of LNTH or the staff of the SEC, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (6) to this Form 4.

SEC source: 0000899243-22-009811 · doc4.xml · nonDerivative · entry 4

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 718,869

F2 · kind: The Company requires certain senior executives to cover tax liabilities resulting from the vesting of their equity awards pursuant to sell-to-cover transactions in compliance with Rule 10b5-1. The transaction reported in this Form 4 was effected in compliance with Rule 10b5-1 to satisfy withholding tax liabilities of the Reporting Person associated with the vesting of restricted stock previously granted and reported on a previously filed Form 4.

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $49.69 to $50.63, inclusive. The reporting person undertakes to provide to LNTH any security holder of LNTH or the staff of the SEC, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (5) to this Form 4.

SEC source: 0000899243-22-009811 · doc4.xml · derivative · entry 6

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 42,822

Underlying: Common Stock · 42,822 shares

Expires 2032-03-03

F7 · derivative.exercise_date: The option vests in three equal annual installments beginning on March 3, 2023.

SEC source: 0000899243-22-009811 · doc4.xml · nonDerivative · entry 3

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 719,566

F2 · kind: The Company requires certain senior executives to cover tax liabilities resulting from the vesting of their equity awards pursuant to sell-to-cover transactions in compliance with Rule 10b5-1. The transaction reported in this Form 4 was effected in compliance with Rule 10b5-1 to satisfy withholding tax liabilities of the Reporting Person associated with the vesting of restricted stock previously granted and reported on a previously filed Form 4.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $52.46 to $52.715, inclusive. The reporting person undertakes to provide to LNTH any security holder of LNTH or the staff of the SEC, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (4) to this Form 4.

SEC source: 0000899243-22-009811 · doc4.xml · nonDerivative · entry 2

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 721,326

F2 · kind: The Company requires certain senior executives to cover tax liabilities resulting from the vesting of their equity awards pursuant to sell-to-cover transactions in compliance with Rule 10b5-1. The transaction reported in this Form 4 was effected in compliance with Rule 10b5-1 to satisfy withholding tax liabilities of the Reporting Person associated with the vesting of restricted stock previously granted and reported on a previously filed Form 4.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $51.42 to $52.35, inclusive. The reporting person undertakes to provide to Lantheus Holdings, Inc., ("LNTH") any security holder of LNTH or the staff of the Securities and Exchange Commission ("SEC"), upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (3) to this Form 4.

SEC source: 0000899243-22-009811 · doc4.xml · nonDerivative · entry 1

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 730,739

F1 · shares: Consists of 25,035 restricted stock units that vest in equal installments over a three-year period and 50,070 Total Shareholder Return performance-based restricted stock units ("PSUs") that cliff vest following a three-year performance period. The amount of PSUs included in this Report reflects the target award, however the ultimate award size can range from 0% to 200% of the target based on the actual performance achieved at the end of the performance period.

SEC source: 0000899243-22-008817 · doc4.xml · nonDerivative · entry 3

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 655,634

F2 · kind: The Company requires certain senior executives to cover tax liabilities resulting from the vesting of their equity awards pursuant to sell-to-cover transactions in compliance with Rule 10b5-1. The transaction reported in this Form 4 was effected in compliance with Rule 10b5-1 to satisfy withholding tax liabilities of the Reporting Person associated with the vesting of restricted stock previously granted and reported on a previously filed Form 4.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $46.69 to $47.47, inclusive. The reporting person undertakes to provide to Lantheus Holdings, Inc., ("LNTH") any security holder of LNTH or the staff of the Securities and Exchange Commission ("SEC"), upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (4) to this Form 4.

SEC source: 0000899243-22-008817 · doc4.xml · nonDerivative · entry 2

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 668,015

F2 · kind: The Company requires certain senior executives to cover tax liabilities resulting from the vesting of their equity awards pursuant to sell-to-cover transactions in compliance with Rule 10b5-1. The transaction reported in this Form 4 was effected in compliance with Rule 10b5-1 to satisfy withholding tax liabilities of the Reporting Person associated with the vesting of restricted stock previously granted and reported on a previously filed Form 4.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $45.69 to $46.68, inclusive. The reporting person undertakes to provide to Lantheus Holdings, Inc., ("LNTH") any security holder of LNTH or the staff of the Securities and Exchange Commission ("SEC"), upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (3) to this Form 4.

SEC source: 0000899243-22-008817 · doc4.xml · nonDerivative · entry 1

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 699,543

F1 · shares: The transaction reported in this Form 4 reflects additional shares of common stock issued by the Company to the reporting person upon the vesting of relative Total Shareholder Return performance-based restricted stock units ("PSUs") that were previously granted and reported on a Form 4 filed on February 27, 2019. That original Form 4 reflected 100% of the target number of shares underlying the PSUs. The number of shares that actually vested under the PSUs equaled 188% of the target number of shares. Accordingly, the number of shares reported in this Form 4 reflects the difference between the number of shares that actually vested under the PSUs and the target number of shares originally reported.

SEC source: 0000899243-22-000907 · doc4.xml · nonDerivative · entry 1

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 660,749

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 10, 2021.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $28.435 to $28.76, inclusive. The reporting person undertakes to provide to Lantheus Holdings, Inc. ("LNTH"), any security holder of LNTH or the staff of the Securities and Exchange Commission ("SEC"), upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (2) to this Form 4.

SEC source: 0000899243-21-044566 · doc4.xml · nonDerivative · entry 1

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 674,849

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 10, 2021.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $29.87 to $30.34, inclusive. The reporting person undertakes to provide to Lantheus Holdings, Inc., ("LNTH") any security holder of LNTH or the staff of the Securities and Exchange Commission ("SEC"), upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (2) to this Form 4.

SEC source: 0000899243-21-032763 · doc4.xml · nonDerivative · entry 1

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 688,182

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 10, 2021.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $25.50 to $26.23, inclusive. The reporting person undertakes to provide to Lantheus Holdings, Inc., ("LNTH") any security holder of LNTH or the staff of the Securities and Exchange Commission ("SEC"), upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (2) to this Form 4.

SEC source: 0000899243-21-015811 · doc4.xml · nonDerivative · entry 1

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 703,762

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 10, 2021.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $20.41 to $20.92, inclusive. The reporting person undertakes to provide to Lantheus Holdings, Inc., ("LNTH") any security holder of LNTH or the staff of the Securities and Exchange Commission ("SEC"), upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (2) to this Form 4.

F3 · balance_after: Reduced by one share to reflect a rounding error correction to the total number of shares reported on the fourth line of Table I in Column 4 in the Form 4 report filed on March 8, 2021.

SEC source: 0000899243-21-010795 · doc4.xml · nonDerivative · entry 2

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 723,184

F3 · kind: As noted in footnote (1) above, on March 5, 2021, the reporting person sold 27,157 shares pursuant to a Rule 10b5-1 trading plan. The reporting person's broker erroneously sold shares based on the original target number of shares under a performance share grant rather than the actual number of shares that vested. The amount reported represents the number of shares reacquired by the broker to reverse the error. The weighted average price for the reacquired shares was $19.4659, reacquired in multiple transactions at prices ranging from $19.295 to $19.56, inclusive. The reporting person undertakes to provide to LNTH, any security holder of LNTH or the staff of the SEC, upon request, full information regarding the number of shares reacquired at each separate price within the ranges set forth in this footnote (3) to this Form 4.

F3 · shares: As noted in footnote (1) above, on March 5, 2021, the reporting person sold 27,157 shares pursuant to a Rule 10b5-1 trading plan. The reporting person's broker erroneously sold shares based on the original target number of shares under a performance share grant rather than the actual number of shares that vested. The amount reported represents the number of shares reacquired by the broker to reverse the error. The weighted average price for the reacquired shares was $19.4659, reacquired in multiple transactions at prices ranging from $19.295 to $19.56, inclusive. The reporting person undertakes to provide to LNTH, any security holder of LNTH or the staff of the SEC, upon request, full information regarding the number of shares reacquired at each separate price within the ranges set forth in this footnote (3) to this Form 4.

F3 · price: As noted in footnote (1) above, on March 5, 2021, the reporting person sold 27,157 shares pursuant to a Rule 10b5-1 trading plan. The reporting person's broker erroneously sold shares based on the original target number of shares under a performance share grant rather than the actual number of shares that vested. The amount reported represents the number of shares reacquired by the broker to reverse the error. The weighted average price for the reacquired shares was $19.4659, reacquired in multiple transactions at prices ranging from $19.295 to $19.56, inclusive. The reporting person undertakes to provide to LNTH, any security holder of LNTH or the staff of the SEC, upon request, full information regarding the number of shares reacquired at each separate price within the ranges set forth in this footnote (3) to this Form 4.

SEC source: 0000899243-21-010795 · doc4.xml · nonDerivative · entry 1

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 711,720

F1 · kind: The Company requires certain senior executives to cover tax liabilities resulting from the vesting of their equity awards pursuant to sell-to-cover transactions in compliance with Rule 10b5-1. The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 15, 2020, to satisfy withholding tax liabilities of the Reporting Person associated with the vesting of restricted stock previously granted and reported on a previously filed Form 4.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $18.015 to $18.60, inclusive. The reporting person undertakes to provide to Lantheus Holdings, Inc., ("LNTH") any security holder of LNTH or the staff of the Securities and Exchange Commission ("SEC"), upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (2) to this Form 4.

SEC source: 0000899243-21-010520 · doc4.xml · nonDerivative · entry 4

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 738,877

SEC source: 0000899243-21-010520 · doc4.xml · nonDerivative · entry 3

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By son

Disclosed balance after: 3,700

F2 · kind: This transaction involved a gift of securities by the reporting person to her son, who shares reporting person's household. The reporting person disclaims beneficial ownership of the shares held by her son, and this report should not be deemed an admission that the reporting person is the beneficial owner of her son's shares for purposes of Section 16 or for any other purpose.

SEC source: 0000899243-21-010520 · doc4.xml · nonDerivative · entry 2

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 576,539

F2 · kind: This transaction involved a gift of securities by the reporting person to her son, who shares reporting person's household. The reporting person disclaims beneficial ownership of the shares held by her son, and this report should not be deemed an admission that the reporting person is the beneficial owner of her son's shares for purposes of Section 16 or for any other purpose.

SEC source: 0000899243-21-010520 · doc4.xml · nonDerivative · entry 1

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 578,039

F1 · balance_after: Reduced by 25,254 shares to reflect the forfeiture of restricted performance stock previously granted and reported on a previously filed Form 4 but which did not vest.

SEC source: 0000899243-20-020469 · doc4.xml · nonDerivative · entry 1

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 604,793

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on November 14, 2019.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $16.00 to $16.04, inclusive. The reporting person undertakes to provide to Lantheus Holdings, Inc., ("LNTH") any security holder of LNTH or the staff of the Securities and Exchange Commission ("SEC"), upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (2) to this Form 4.

SEC source: 0000899243-20-019529 · doc4.xml · nonDerivative · entry 1

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 607,793

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on November 14, 2019.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $16.00 to $16.03, inclusive. The reporting person undertakes to provide to Lantheus Holdings, Inc., ("LNTH") any security holder of LNTH or the staff of the Securities and Exchange Commission ("SEC"), upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (2) to this Form 4.

SEC source: 0000899243-21-006307 · doc5.xml · nonDerivative · entry 3

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By son

Disclosed balance after: 2,200

F1 · kind: This transaction involved a gift of securities by the reporting person to her son, who shares reporting person's household. The reporting person disclaims beneficial ownership of the shares held by her son, and this report should not be deemed an admission that the reporting person is the beneficial owner of her son's shares for purposes of Section 16 or for any other purpose.

SEC source: 0000899243-21-006307 · doc5.xml · nonDerivative · entry 2

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 604,793

F1 · kind: This transaction involved a gift of securities by the reporting person to her son, who shares reporting person's household. The reporting person disclaims beneficial ownership of the shares held by her son, and this report should not be deemed an admission that the reporting person is the beneficial owner of her son's shares for purposes of Section 16 or for any other purpose.

SEC source: 0000899243-21-006307 · doc5.xml · nonDerivative · entry 1

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 606,993

SEC source: 0000899243-20-011559 · doc4.xml · nonDerivative · entry 1

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 634,318

F1 · kind: The Company requires certain senior executives to cover tax liabilities resulting from the vesting of their equity awards pursuant to sell-to-cover transactions in compliance with Rule 10b5-1. The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on November 14, 2019, to satisfy withholding tax liabilities of the Reporting Person associated with the vesting of restricted stock previously granted and reported on a previously filed Form 4.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $13.31 to $13.8975, inclusive. The reporting person undertakes to provide to Lantheus Holdings, Inc., ("LNTH") any security holder of LNTH or the staff of the Securities and Exchange Commission ("SEC"), upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (2) to this Form 4.

SEC source: 0000899243-20-007198 · doc4.xml · nonDerivative · entry 2

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 664,351

F1 · kind: The Company requires certain senior executives to cover tax liabilities resulting from the vesting of their equity awards pursuant to sell-to-cover transactions in compliance with Rule 10b5-1. The transactions reporting in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on November 14, 2019, to satisfy withholding tax liabilities of the Reporting Person associated with the vesting of restricted stock previously granted and reported on a previously filed Form 4.

F2 · price: The price reported in Column 4 is a weighted average prices. These shares were sold in multiple transactions at prices ranging from $15.115 to $15.525, inclusive. The reporting person undertakes to provide to Lantheus Holdings, Inc. ("LNTH") any security holder of LNTH or the staff of the Securities and Exchange Commission ("SEC"), upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (2) to the Form 4.

SEC source: 0000899243-20-007198 · doc4.xml · nonDerivative · entry 1

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 673,370

SEC source: 0000899243-20-006256 · doc4.xml · nonDerivative · entry 2

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 524,399

F3 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on November 14, 2019.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $16.0 to $16.1, inclusive. The reporting person undertakes to provide to LNTH, any security holder of LNTH or the staff of the SEC, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (4) to this Form 4.

SEC source: 0000899243-20-006256 · doc4.xml · nonDerivative · entry 1

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 549,399

F1 · kind: The Company requires certain senior executives to cover tax liabilities resulting from the vesting of their equity awards pursuant to sell-to-cover transactions in compliance with Rule 10b5-1. The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on November 14, 2019, to satisfy withholding tax liabilities of the Reporting Person associated with the vesting of restricted stock previously granted and reported on a previously filed Form 4.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $16.86 to $17.3, inclusive. The reporting person undertakes to provide to Lantheus Holdings, Inc., ("LNTH") any security holder of LNTH or the staff of the Securities and Exchange Commission ("SEC"), upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (2) to this Form 4.

SEC source: 0000899243-20-005908 · doc4.xml · nonDerivative · entry 1

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 556,014

F1 · kind: The Company requires certain senior executives to cover tax liabilities resulting from the vesting of their equity awards pursuant to sell-to-cover transactions in compliance with Rule 10b5-1. The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on November 14, 2019, to satisfy withholding tax liabilities of the Reporting Person associated with the vesting of restricted stock previously granted and reported on a previously filed Form 4.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $15.90 to $16.17, inclusive. The reporting person undertakes to provide to Lantheus Holdings, Inc., ("LNTH") any security holder of LNTH or the staff of the Securities and Exchange Commission ("SEC"), upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (2) to this Form 4.

SEC source: 0000899243-20-005496 · doc4.xml · nonDerivative · entry 1

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 565,912

F1 · kind: The transaction reported in this Form 4 reports additional restricted stock earned by the reporting person as a result of the overachievement of certain performance criteria included in the 2017 performance-based stock award previously granted and reported on a previously filed Form 4. The amount reported in this Form 4 report was finally determined at a meeting of the Compensation Committee of the Company held on February 19, 2020.

SEC source: 0000899243-19-029958 · doc4.xml · nonDerivative · entry 1

Heino Mary Anne · CIK 0001610676 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 563,034

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 8, 2019.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $20.57 to $21.10, inclusive. The reporting person undertakes to provide to Lantheus Holdings, Inc., ("LNTH") any security holder of LNTH or the staff of the Securities and Exchange Commission ("SEC"), upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (2) to this Form 4.