Politan Capital Management GP LLC

SEC source: 0001104659-26-073533 · tm2617401-14_4seq1.xml · derivative · entry 2

Politan Capital Management LP · CIK 0001885245 · Director by deputization

Politan Capital Management GP LLC · CIK 0001984176 · Director by deputization

Politan Capital Partners GP LLC · CIK 0001984175 · Director by deputization

Koffey Quentin · CIK 0001984174 · Director by deputization

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 0

Underlying: Common Stock · 130,869 shares

Expires not disclosed

F8 · derivative.exercise_price: On June 10, 2026, the March 12 Forward Contract (defined below) terminated in accordance with its terms. On March 12, 2026, Politan Master Fund, entered into a forward sale contract (the "March 12 Forward Contract") with the Counterparty. The March 12 Forward Contract obligated Politan Master Fund to deliver 130,869 common shares of MASI on the maturity date, August 13, 2026, subject to customary adjustments. Pursuant to the terms of the March 12 Forward Contract, the maturity date of the March 12 Forward Contract could have been extended one month to September 13, 2026, at the election of Politan Master Fund.

F9 · derivative.exercise_price: (continued from footnote 8) In exchange for entering into the March 12 Forward Contract, Politan Master Fund received an upfront payment of $22,749,606 on or around the trade date, which was based on a trade price of $175.48 per share. As a result of the Merger, pursuant to the terms of the March 12 Forward Contract, the March 12 Forward Contract terminated and Politan Master Fund paid the Counterparty $23,556,420.00, based on a price of $180.00 per share, as adjusted in accordance with the terms of the March 12 Forward Contract.

F8 · kind: On June 10, 2026, the March 12 Forward Contract (defined below) terminated in accordance with its terms. On March 12, 2026, Politan Master Fund, entered into a forward sale contract (the "March 12 Forward Contract") with the Counterparty. The March 12 Forward Contract obligated Politan Master Fund to deliver 130,869 common shares of MASI on the maturity date, August 13, 2026, subject to customary adjustments. Pursuant to the terms of the March 12 Forward Contract, the maturity date of the March 12 Forward Contract could have been extended one month to September 13, 2026, at the election of Politan Master Fund.

F9 · kind: (continued from footnote 8) In exchange for entering into the March 12 Forward Contract, Politan Master Fund received an upfront payment of $22,749,606 on or around the trade date, which was based on a trade price of $175.48 per share. As a result of the Merger, pursuant to the terms of the March 12 Forward Contract, the March 12 Forward Contract terminated and Politan Master Fund paid the Counterparty $23,556,420.00, based on a price of $180.00 per share, as adjusted in accordance with the terms of the March 12 Forward Contract.

F8 · shares: On June 10, 2026, the March 12 Forward Contract (defined below) terminated in accordance with its terms. On March 12, 2026, Politan Master Fund, entered into a forward sale contract (the "March 12 Forward Contract") with the Counterparty. The March 12 Forward Contract obligated Politan Master Fund to deliver 130,869 common shares of MASI on the maturity date, August 13, 2026, subject to customary adjustments. Pursuant to the terms of the March 12 Forward Contract, the maturity date of the March 12 Forward Contract could have been extended one month to September 13, 2026, at the election of Politan Master Fund.

F9 · shares: (continued from footnote 8) In exchange for entering into the March 12 Forward Contract, Politan Master Fund received an upfront payment of $22,749,606 on or around the trade date, which was based on a trade price of $175.48 per share. As a result of the Merger, pursuant to the terms of the March 12 Forward Contract, the March 12 Forward Contract terminated and Politan Master Fund paid the Counterparty $23,556,420.00, based on a price of $180.00 per share, as adjusted in accordance with the terms of the March 12 Forward Contract.

F8 · price: On June 10, 2026, the March 12 Forward Contract (defined below) terminated in accordance with its terms. On March 12, 2026, Politan Master Fund, entered into a forward sale contract (the "March 12 Forward Contract") with the Counterparty. The March 12 Forward Contract obligated Politan Master Fund to deliver 130,869 common shares of MASI on the maturity date, August 13, 2026, subject to customary adjustments. Pursuant to the terms of the March 12 Forward Contract, the maturity date of the March 12 Forward Contract could have been extended one month to September 13, 2026, at the election of Politan Master Fund.

F9 · price: (continued from footnote 8) In exchange for entering into the March 12 Forward Contract, Politan Master Fund received an upfront payment of $22,749,606 on or around the trade date, which was based on a trade price of $175.48 per share. As a result of the Merger, pursuant to the terms of the March 12 Forward Contract, the March 12 Forward Contract terminated and Politan Master Fund paid the Counterparty $23,556,420.00, based on a price of $180.00 per share, as adjusted in accordance with the terms of the March 12 Forward Contract.

F8 · derivative.exercise_date: On June 10, 2026, the March 12 Forward Contract (defined below) terminated in accordance with its terms. On March 12, 2026, Politan Master Fund, entered into a forward sale contract (the "March 12 Forward Contract") with the Counterparty. The March 12 Forward Contract obligated Politan Master Fund to deliver 130,869 common shares of MASI on the maturity date, August 13, 2026, subject to customary adjustments. Pursuant to the terms of the March 12 Forward Contract, the maturity date of the March 12 Forward Contract could have been extended one month to September 13, 2026, at the election of Politan Master Fund.

F9 · derivative.exercise_date: (continued from footnote 8) In exchange for entering into the March 12 Forward Contract, Politan Master Fund received an upfront payment of $22,749,606 on or around the trade date, which was based on a trade price of $175.48 per share. As a result of the Merger, pursuant to the terms of the March 12 Forward Contract, the March 12 Forward Contract terminated and Politan Master Fund paid the Counterparty $23,556,420.00, based on a price of $180.00 per share, as adjusted in accordance with the terms of the March 12 Forward Contract.

F8 · derivative.expiration_date: On June 10, 2026, the March 12 Forward Contract (defined below) terminated in accordance with its terms. On March 12, 2026, Politan Master Fund, entered into a forward sale contract (the "March 12 Forward Contract") with the Counterparty. The March 12 Forward Contract obligated Politan Master Fund to deliver 130,869 common shares of MASI on the maturity date, August 13, 2026, subject to customary adjustments. Pursuant to the terms of the March 12 Forward Contract, the maturity date of the March 12 Forward Contract could have been extended one month to September 13, 2026, at the election of Politan Master Fund.

F9 · derivative.expiration_date: (continued from footnote 8) In exchange for entering into the March 12 Forward Contract, Politan Master Fund received an upfront payment of $22,749,606 on or around the trade date, which was based on a trade price of $175.48 per share. As a result of the Merger, pursuant to the terms of the March 12 Forward Contract, the March 12 Forward Contract terminated and Politan Master Fund paid the Counterparty $23,556,420.00, based on a price of $180.00 per share, as adjusted in accordance with the terms of the March 12 Forward Contract.

F3 · ownership.nature: In addition to Politan Capital Management LP, a Delaware limited partnership ("Politan"), this Form 4 is being filed jointly by Politan Capital Management GP LLC, a Delaware limited liability company ("Politan Management"), Politan Capital Partners GP LLC, a Delaware limited liability company ("Politan GP"), and Quentin Koffey, a citizen of the United States of America (together with Politan, Politan Management and Politan GP, the "Reporting Persons"), each of whom has the same business address as Politan and may be deemed to have a pecuniary interest in securities reported on this Form 4 (the "Subject Securities").

F4 · ownership.nature: Politan is the investment advisor to certain funds, including Politan Capital Partners LP, a Delaware limited partnership ("Politan LP"), Politan Capital Offshore Partners LP, a Cayman Islands exempted limited partnership ("Politan Offshore"), and Politan Master Fund (collectively with Politan Offshore and Politan LP, the "Politan Funds").

F5 · ownership.nature: Politan, as the investment advisor of the Politan Funds, may be deemed to be the beneficial owner of the Subject Securities for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934. As the general partner of Politan, Politan Management may be deemed to be the beneficial owner of the Subject Securities for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934. As the general partner of the Politan Funds, Politan GP may be deemed to be the beneficial owner of the Subject Securities for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934.

F6 · ownership.nature: By virtue of Mr. Koffey's position as managing partner and chief investment officer of Politan, and as the managing member of Politan Management and Politan GP, Mr. Koffey may be deemed to be the beneficial owner of the Subject Securities for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934. Each of the Reporting Persons disclaims any beneficial ownership of any of the Subject Securities, except to the extent of any pecuniary interest therein.

F7 · ownership.nature: Mr. Koffey was a member of the board of directors of the Issuer of the Subject Securities, and as a result, each of the other Reporting Persons may be directors by deputization for purposes of Section 16 of the Securities Exchange Act of 1934.

SEC source: 0001104659-26-073533 · tm2617401-14_4seq1.xml · derivative · entry 1

Politan Capital Management LP · CIK 0001885245 · Director by deputization

Politan Capital Management GP LLC · CIK 0001984176 · Director by deputization

Politan Capital Partners GP LLC · CIK 0001984175 · Director by deputization

Koffey Quentin · CIK 0001984174 · Director by deputization

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 0

Underlying: Common Stock · 142,681 shares

Expires not disclosed

F1 · derivative.exercise_price: On June 10, 2026, the March 11 Forward Contract (defined below) terminated in accordance with its terms. On March 11, 2026, Politan Capital Partners Master Fund LP, a Cayman Islands exempted limited partnership ("Politan Master Fund"), entered into a forward sale contract (the "March 11 Forward Contract") with a financial institution (the "Counterparty"). The March 11 Forward Contract obligated Politan Master Fund to deliver 142,681 common shares of MASI on the maturity date, August 12, 2026, subject to customary adjustments. Pursuant to the terms of the March 11 Forward Contract, the maturity date of the March 11 Forward Contract could have been extended one month to September 12, 2026, at the election of Politan Master Fund.

F2 · derivative.exercise_price: (continued from footnote 1) In exchange for entering into the March 11 Forward Contract, Politan Master Fund received an upfront payment of $24,802,095.85 on or around the trade date, which was based on a trade price of $175.48 per share. As a result of the Merger (defined below), pursuant to the terms of the March 11 Forward Contract, the March 11 Forward Contract terminated and Politan Master Fund paid the Counterparty $25,682,580.00, based on a price of $180.00 per share, as adjusted in accordance with the terms of the March 11 Forward Contract.

F1 · kind: On June 10, 2026, the March 11 Forward Contract (defined below) terminated in accordance with its terms. On March 11, 2026, Politan Capital Partners Master Fund LP, a Cayman Islands exempted limited partnership ("Politan Master Fund"), entered into a forward sale contract (the "March 11 Forward Contract") with a financial institution (the "Counterparty"). The March 11 Forward Contract obligated Politan Master Fund to deliver 142,681 common shares of MASI on the maturity date, August 12, 2026, subject to customary adjustments. Pursuant to the terms of the March 11 Forward Contract, the maturity date of the March 11 Forward Contract could have been extended one month to September 12, 2026, at the election of Politan Master Fund.

F2 · kind: (continued from footnote 1) In exchange for entering into the March 11 Forward Contract, Politan Master Fund received an upfront payment of $24,802,095.85 on or around the trade date, which was based on a trade price of $175.48 per share. As a result of the Merger (defined below), pursuant to the terms of the March 11 Forward Contract, the March 11 Forward Contract terminated and Politan Master Fund paid the Counterparty $25,682,580.00, based on a price of $180.00 per share, as adjusted in accordance with the terms of the March 11 Forward Contract.

F1 · shares: On June 10, 2026, the March 11 Forward Contract (defined below) terminated in accordance with its terms. On March 11, 2026, Politan Capital Partners Master Fund LP, a Cayman Islands exempted limited partnership ("Politan Master Fund"), entered into a forward sale contract (the "March 11 Forward Contract") with a financial institution (the "Counterparty"). The March 11 Forward Contract obligated Politan Master Fund to deliver 142,681 common shares of MASI on the maturity date, August 12, 2026, subject to customary adjustments. Pursuant to the terms of the March 11 Forward Contract, the maturity date of the March 11 Forward Contract could have been extended one month to September 12, 2026, at the election of Politan Master Fund.

F2 · shares: (continued from footnote 1) In exchange for entering into the March 11 Forward Contract, Politan Master Fund received an upfront payment of $24,802,095.85 on or around the trade date, which was based on a trade price of $175.48 per share. As a result of the Merger (defined below), pursuant to the terms of the March 11 Forward Contract, the March 11 Forward Contract terminated and Politan Master Fund paid the Counterparty $25,682,580.00, based on a price of $180.00 per share, as adjusted in accordance with the terms of the March 11 Forward Contract.

F1 · price: On June 10, 2026, the March 11 Forward Contract (defined below) terminated in accordance with its terms. On March 11, 2026, Politan Capital Partners Master Fund LP, a Cayman Islands exempted limited partnership ("Politan Master Fund"), entered into a forward sale contract (the "March 11 Forward Contract") with a financial institution (the "Counterparty"). The March 11 Forward Contract obligated Politan Master Fund to deliver 142,681 common shares of MASI on the maturity date, August 12, 2026, subject to customary adjustments. Pursuant to the terms of the March 11 Forward Contract, the maturity date of the March 11 Forward Contract could have been extended one month to September 12, 2026, at the election of Politan Master Fund.

F2 · price: (continued from footnote 1) In exchange for entering into the March 11 Forward Contract, Politan Master Fund received an upfront payment of $24,802,095.85 on or around the trade date, which was based on a trade price of $175.48 per share. As a result of the Merger (defined below), pursuant to the terms of the March 11 Forward Contract, the March 11 Forward Contract terminated and Politan Master Fund paid the Counterparty $25,682,580.00, based on a price of $180.00 per share, as adjusted in accordance with the terms of the March 11 Forward Contract.

F1 · derivative.exercise_date: On June 10, 2026, the March 11 Forward Contract (defined below) terminated in accordance with its terms. On March 11, 2026, Politan Capital Partners Master Fund LP, a Cayman Islands exempted limited partnership ("Politan Master Fund"), entered into a forward sale contract (the "March 11 Forward Contract") with a financial institution (the "Counterparty"). The March 11 Forward Contract obligated Politan Master Fund to deliver 142,681 common shares of MASI on the maturity date, August 12, 2026, subject to customary adjustments. Pursuant to the terms of the March 11 Forward Contract, the maturity date of the March 11 Forward Contract could have been extended one month to September 12, 2026, at the election of Politan Master Fund.

F2 · derivative.exercise_date: (continued from footnote 1) In exchange for entering into the March 11 Forward Contract, Politan Master Fund received an upfront payment of $24,802,095.85 on or around the trade date, which was based on a trade price of $175.48 per share. As a result of the Merger (defined below), pursuant to the terms of the March 11 Forward Contract, the March 11 Forward Contract terminated and Politan Master Fund paid the Counterparty $25,682,580.00, based on a price of $180.00 per share, as adjusted in accordance with the terms of the March 11 Forward Contract.

F1 · derivative.expiration_date: On June 10, 2026, the March 11 Forward Contract (defined below) terminated in accordance with its terms. On March 11, 2026, Politan Capital Partners Master Fund LP, a Cayman Islands exempted limited partnership ("Politan Master Fund"), entered into a forward sale contract (the "March 11 Forward Contract") with a financial institution (the "Counterparty"). The March 11 Forward Contract obligated Politan Master Fund to deliver 142,681 common shares of MASI on the maturity date, August 12, 2026, subject to customary adjustments. Pursuant to the terms of the March 11 Forward Contract, the maturity date of the March 11 Forward Contract could have been extended one month to September 12, 2026, at the election of Politan Master Fund.

F2 · derivative.expiration_date: (continued from footnote 1) In exchange for entering into the March 11 Forward Contract, Politan Master Fund received an upfront payment of $24,802,095.85 on or around the trade date, which was based on a trade price of $175.48 per share. As a result of the Merger (defined below), pursuant to the terms of the March 11 Forward Contract, the March 11 Forward Contract terminated and Politan Master Fund paid the Counterparty $25,682,580.00, based on a price of $180.00 per share, as adjusted in accordance with the terms of the March 11 Forward Contract.

F3 · ownership.nature: In addition to Politan Capital Management LP, a Delaware limited partnership ("Politan"), this Form 4 is being filed jointly by Politan Capital Management GP LLC, a Delaware limited liability company ("Politan Management"), Politan Capital Partners GP LLC, a Delaware limited liability company ("Politan GP"), and Quentin Koffey, a citizen of the United States of America (together with Politan, Politan Management and Politan GP, the "Reporting Persons"), each of whom has the same business address as Politan and may be deemed to have a pecuniary interest in securities reported on this Form 4 (the "Subject Securities").

F4 · ownership.nature: Politan is the investment advisor to certain funds, including Politan Capital Partners LP, a Delaware limited partnership ("Politan LP"), Politan Capital Offshore Partners LP, a Cayman Islands exempted limited partnership ("Politan Offshore"), and Politan Master Fund (collectively with Politan Offshore and Politan LP, the "Politan Funds").

F5 · ownership.nature: Politan, as the investment advisor of the Politan Funds, may be deemed to be the beneficial owner of the Subject Securities for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934. As the general partner of Politan, Politan Management may be deemed to be the beneficial owner of the Subject Securities for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934. As the general partner of the Politan Funds, Politan GP may be deemed to be the beneficial owner of the Subject Securities for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934.

F6 · ownership.nature: By virtue of Mr. Koffey's position as managing partner and chief investment officer of Politan, and as the managing member of Politan Management and Politan GP, Mr. Koffey may be deemed to be the beneficial owner of the Subject Securities for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934. Each of the Reporting Persons disclaims any beneficial ownership of any of the Subject Securities, except to the extent of any pecuniary interest therein.

F7 · ownership.nature: Mr. Koffey was a member of the board of directors of the Issuer of the Subject Securities, and as a result, each of the other Reporting Persons may be directors by deputization for purposes of Section 16 of the Securities Exchange Act of 1934.

SEC source: 0001104659-26-073531 · tm2617401-13_4seq1.xml · derivative · entry 2

Politan Capital Management LP · CIK 0001885245 · Director by deputization

Koffey Quentin · CIK 0001984174 · Director by deputization

Politan Capital Partners GP LLC · CIK 0001984175 · Director by deputization

Politan Capital Management GP LLC · CIK 0001984176 · Director by deputization

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 0

Underlying: Common Stock · 1,119 shares

Expires not disclosed

F9 · derivative.exercise_price: Represents the unvested portion of RSUs granted on April 23, 2026, which award of RSUs was to vest on the earlier of the first anniversary of the grant date or the next annual meeting of stockholders following the date of grant.

F8 · price: On June 10, 2026, at the effective time of the Merger, each of the Issuer's restricted stock units ("RSUs") held by the Issuer's non-employee directors was canceled and converted into the right to receive an amount in cash equal to the Per Share Merger Consideration.

F1 · derivative.exercise_date: On June 10, 2026, pursuant to the Agreement and Plan of Merger, dated as of February 16, 2026, by and among Masimo Corporation (the "Issuer"), Danaher Corporation ("Parent") and Mobius Merger Sub, Inc. ("Merger Sub"), Merger Sub merged with and into the Issuer (the "Merger"), with the Issuer continuing as the surviving corporation and a wholly owned subsidiary of Parent.

F8 · derivative.exercise_date: On June 10, 2026, at the effective time of the Merger, each of the Issuer's restricted stock units ("RSUs") held by the Issuer's non-employee directors was canceled and converted into the right to receive an amount in cash equal to the Per Share Merger Consideration.

F9 · derivative.exercise_date: Represents the unvested portion of RSUs granted on April 23, 2026, which award of RSUs was to vest on the earlier of the first anniversary of the grant date or the next annual meeting of stockholders following the date of grant.

F1 · derivative.expiration_date: On June 10, 2026, pursuant to the Agreement and Plan of Merger, dated as of February 16, 2026, by and among Masimo Corporation (the "Issuer"), Danaher Corporation ("Parent") and Mobius Merger Sub, Inc. ("Merger Sub"), Merger Sub merged with and into the Issuer (the "Merger"), with the Issuer continuing as the surviving corporation and a wholly owned subsidiary of Parent.

F8 · derivative.expiration_date: On June 10, 2026, at the effective time of the Merger, each of the Issuer's restricted stock units ("RSUs") held by the Issuer's non-employee directors was canceled and converted into the right to receive an amount in cash equal to the Per Share Merger Consideration.

F9 · derivative.expiration_date: Represents the unvested portion of RSUs granted on April 23, 2026, which award of RSUs was to vest on the earlier of the first anniversary of the grant date or the next annual meeting of stockholders following the date of grant.

F10 · ownership.nature: These RSUs are held directly by Mr. Koffey.

SEC source: 0001104659-26-073531 · tm2617401-13_4seq1.xml · nonDerivative · entry 1

Politan Capital Management LP · CIK 0001885245 · Director by deputization

Koffey Quentin · CIK 0001984174 · Director by deputization

Politan Capital Partners GP LLC · CIK 0001984175 · Director by deputization

Politan Capital Management GP LLC · CIK 0001984176 · Director by deputization

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 0

F1 · price: On June 10, 2026, pursuant to the Agreement and Plan of Merger, dated as of February 16, 2026, by and among Masimo Corporation (the "Issuer"), Danaher Corporation ("Parent") and Mobius Merger Sub, Inc. ("Merger Sub"), Merger Sub merged with and into the Issuer (the "Merger"), with the Issuer continuing as the surviving corporation and a wholly owned subsidiary of Parent.

F2 · price: At the effective time of the Merger, each share of the Issuer's common stock, par value $0.001 per share (the "Common Stock") issued and outstanding immediately prior to the effective time (other than certain excluded and dissenting shares) was canceled and converted into the right to receive $180.00 in cash, without interest (the "Per Share Merger Consideration").

F3 · ownership.nature: This Form 4 is being filed jointly by Politan Capital Management LP, a Delaware limited partnership ("Politan"), Politan Capital Management GP LLC, a Delaware limited liability company ("Politan Management"), Politan Capital Partners GP LLC, a Delaware limited liability company ("Politan GP"), and Quentin Koffey, a citizen of the United States of America (collectively, the "Reporting Persons"), each of whom has the same business address as Politan and may be deemed to have a pecuniary interest in the securities reported on this Form 4 (the "Subject Securities").

F4 · ownership.nature: Politan is the investment advisor to certain funds, including Politan Capital Partners LP, a Delaware limited partnership ("Politan LP"), Politan Capital Offshore Partners LP, a Cayman Islands exempted limited partnership ("Politan Offshore"), and Politan Capital Partners Master Fund LP, a Cayman Islands exempted limited partnership ("Politan Master Fund" and, collectively with Politan LP and Politan Offshore, the "Politan Funds").

F5 · ownership.nature: Politan, as the investment advisor of the Politan Funds, may be deemed to be the beneficial owner of the Subject Securities for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934. As the general partner of Politan, Politan Management may be deemed to be the beneficial owner of the Subject Securities for purposes of Rule 16a-1(a). As the general partner of the Politan Funds, Politan GP may be deemed to be the beneficial owner of the Subject Securities for purposes of Rule 16a-1(a).

F6 · ownership.nature: By virtue of Mr. Koffey's position as managing partner and chief investment officer of Politan, and as the managing member of Politan Management and Politan GP, Mr. Koffey may be deemed to be the beneficial owner of the Subject Securities for purposes of Rule 16a-1(a). Each of the Reporting Persons disclaims beneficial ownership of the Subject Securities, except to the extent of any pecuniary interest therein.

F7 · ownership.nature: Mr. Koffey is a member of the board of directors of the Issuer, and as a result, each of the other Reporting Persons may be directors by deputization for purposes of Section 16 of the Securities Exchange Act of 1934.

SEC source: 0001104659-26-027790 · tm268814d1_4seq1.xml · derivative · entry 2

Politan Capital Management LP · CIK 0001885245 · Director by deputization

Politan Capital Management GP LLC · CIK 0001984176 · Director by deputization

Politan Capital Partners GP LLC · CIK 0001984175 · Director by deputization

Koffey Quentin · CIK 0001984174 · Director by deputization

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 130,869

Underlying: Common Stock · 130,869 shares

Expires not disclosed

F8 · derivative.exercise_price: On March 12, 2026, Politan Master Fund, entered into a forward sale contract (the "March 12 Forward Contract") with the Counterparty. The March 12 Forward Contract obligates Politan Master Fund to deliver 130,869 common shares of MASI (the "March 12 Number of Shares") on the maturity date, August 13, 2026, subject to customary adjustments. In exchange, Politan Master Fund will receive an upfront payment of $22,749,606 on or around the trade date, which is based on a trade price of $175.48 per share. Politan Master Fund pledged the March 12 Number of Shares under the March 12 Forward Contract to secure its obligations under the transaction, and retained dividend and voting rights in such pledged shares.

F9 · derivative.exercise_price: (continued from footnote 8) In addition, Politan Master Fund may request to increase the March 12 Number of Shares to be delivered by providing the Counterparty with an Additional Number of Shares Notice, and, if accepted, the details of the updated transaction will be made available by the Counterparty on an Adjustment Notice. The maturity date of the March 12 Forward Contract may be extended one month to September 13, 2026, at the election of Politan Master Fund. Upon maturity, if the March 12 Forward Contract is cash settled the cash settlement price payable by Politan Master Fund will be calculated on the basis of volume weighted average price per share at maturity. Alternatively, if the March 12 Forward Contract is physically settled, Politan Master Fund will deliver the March 12 Number of Shares (together with any additional number of shares listed in any applicable Adjustment Notice) reflecting the total March 12 Number of Shares sold to the Counterparty.

F8 · kind: On March 12, 2026, Politan Master Fund, entered into a forward sale contract (the "March 12 Forward Contract") with the Counterparty. The March 12 Forward Contract obligates Politan Master Fund to deliver 130,869 common shares of MASI (the "March 12 Number of Shares") on the maturity date, August 13, 2026, subject to customary adjustments. In exchange, Politan Master Fund will receive an upfront payment of $22,749,606 on or around the trade date, which is based on a trade price of $175.48 per share. Politan Master Fund pledged the March 12 Number of Shares under the March 12 Forward Contract to secure its obligations under the transaction, and retained dividend and voting rights in such pledged shares.

F9 · kind: (continued from footnote 8) In addition, Politan Master Fund may request to increase the March 12 Number of Shares to be delivered by providing the Counterparty with an Additional Number of Shares Notice, and, if accepted, the details of the updated transaction will be made available by the Counterparty on an Adjustment Notice. The maturity date of the March 12 Forward Contract may be extended one month to September 13, 2026, at the election of Politan Master Fund. Upon maturity, if the March 12 Forward Contract is cash settled the cash settlement price payable by Politan Master Fund will be calculated on the basis of volume weighted average price per share at maturity. Alternatively, if the March 12 Forward Contract is physically settled, Politan Master Fund will deliver the March 12 Number of Shares (together with any additional number of shares listed in any applicable Adjustment Notice) reflecting the total March 12 Number of Shares sold to the Counterparty.

F8 · shares: On March 12, 2026, Politan Master Fund, entered into a forward sale contract (the "March 12 Forward Contract") with the Counterparty. The March 12 Forward Contract obligates Politan Master Fund to deliver 130,869 common shares of MASI (the "March 12 Number of Shares") on the maturity date, August 13, 2026, subject to customary adjustments. In exchange, Politan Master Fund will receive an upfront payment of $22,749,606 on or around the trade date, which is based on a trade price of $175.48 per share. Politan Master Fund pledged the March 12 Number of Shares under the March 12 Forward Contract to secure its obligations under the transaction, and retained dividend and voting rights in such pledged shares.

F9 · shares: (continued from footnote 8) In addition, Politan Master Fund may request to increase the March 12 Number of Shares to be delivered by providing the Counterparty with an Additional Number of Shares Notice, and, if accepted, the details of the updated transaction will be made available by the Counterparty on an Adjustment Notice. The maturity date of the March 12 Forward Contract may be extended one month to September 13, 2026, at the election of Politan Master Fund. Upon maturity, if the March 12 Forward Contract is cash settled the cash settlement price payable by Politan Master Fund will be calculated on the basis of volume weighted average price per share at maturity. Alternatively, if the March 12 Forward Contract is physically settled, Politan Master Fund will deliver the March 12 Number of Shares (together with any additional number of shares listed in any applicable Adjustment Notice) reflecting the total March 12 Number of Shares sold to the Counterparty.

F8 · price: On March 12, 2026, Politan Master Fund, entered into a forward sale contract (the "March 12 Forward Contract") with the Counterparty. The March 12 Forward Contract obligates Politan Master Fund to deliver 130,869 common shares of MASI (the "March 12 Number of Shares") on the maturity date, August 13, 2026, subject to customary adjustments. In exchange, Politan Master Fund will receive an upfront payment of $22,749,606 on or around the trade date, which is based on a trade price of $175.48 per share. Politan Master Fund pledged the March 12 Number of Shares under the March 12 Forward Contract to secure its obligations under the transaction, and retained dividend and voting rights in such pledged shares.

F9 · price: (continued from footnote 8) In addition, Politan Master Fund may request to increase the March 12 Number of Shares to be delivered by providing the Counterparty with an Additional Number of Shares Notice, and, if accepted, the details of the updated transaction will be made available by the Counterparty on an Adjustment Notice. The maturity date of the March 12 Forward Contract may be extended one month to September 13, 2026, at the election of Politan Master Fund. Upon maturity, if the March 12 Forward Contract is cash settled the cash settlement price payable by Politan Master Fund will be calculated on the basis of volume weighted average price per share at maturity. Alternatively, if the March 12 Forward Contract is physically settled, Politan Master Fund will deliver the March 12 Number of Shares (together with any additional number of shares listed in any applicable Adjustment Notice) reflecting the total March 12 Number of Shares sold to the Counterparty.

F8 · derivative.exercise_date: On March 12, 2026, Politan Master Fund, entered into a forward sale contract (the "March 12 Forward Contract") with the Counterparty. The March 12 Forward Contract obligates Politan Master Fund to deliver 130,869 common shares of MASI (the "March 12 Number of Shares") on the maturity date, August 13, 2026, subject to customary adjustments. In exchange, Politan Master Fund will receive an upfront payment of $22,749,606 on or around the trade date, which is based on a trade price of $175.48 per share. Politan Master Fund pledged the March 12 Number of Shares under the March 12 Forward Contract to secure its obligations under the transaction, and retained dividend and voting rights in such pledged shares.

F9 · derivative.exercise_date: (continued from footnote 8) In addition, Politan Master Fund may request to increase the March 12 Number of Shares to be delivered by providing the Counterparty with an Additional Number of Shares Notice, and, if accepted, the details of the updated transaction will be made available by the Counterparty on an Adjustment Notice. The maturity date of the March 12 Forward Contract may be extended one month to September 13, 2026, at the election of Politan Master Fund. Upon maturity, if the March 12 Forward Contract is cash settled the cash settlement price payable by Politan Master Fund will be calculated on the basis of volume weighted average price per share at maturity. Alternatively, if the March 12 Forward Contract is physically settled, Politan Master Fund will deliver the March 12 Number of Shares (together with any additional number of shares listed in any applicable Adjustment Notice) reflecting the total March 12 Number of Shares sold to the Counterparty.

F8 · derivative.expiration_date: On March 12, 2026, Politan Master Fund, entered into a forward sale contract (the "March 12 Forward Contract") with the Counterparty. The March 12 Forward Contract obligates Politan Master Fund to deliver 130,869 common shares of MASI (the "March 12 Number of Shares") on the maturity date, August 13, 2026, subject to customary adjustments. In exchange, Politan Master Fund will receive an upfront payment of $22,749,606 on or around the trade date, which is based on a trade price of $175.48 per share. Politan Master Fund pledged the March 12 Number of Shares under the March 12 Forward Contract to secure its obligations under the transaction, and retained dividend and voting rights in such pledged shares.

F9 · derivative.expiration_date: (continued from footnote 8) In addition, Politan Master Fund may request to increase the March 12 Number of Shares to be delivered by providing the Counterparty with an Additional Number of Shares Notice, and, if accepted, the details of the updated transaction will be made available by the Counterparty on an Adjustment Notice. The maturity date of the March 12 Forward Contract may be extended one month to September 13, 2026, at the election of Politan Master Fund. Upon maturity, if the March 12 Forward Contract is cash settled the cash settlement price payable by Politan Master Fund will be calculated on the basis of volume weighted average price per share at maturity. Alternatively, if the March 12 Forward Contract is physically settled, Politan Master Fund will deliver the March 12 Number of Shares (together with any additional number of shares listed in any applicable Adjustment Notice) reflecting the total March 12 Number of Shares sold to the Counterparty.

F3 · ownership.nature: In addition to Politan Capital Management LP, a Delaware limited partnership ("Politan"), this Form 4 is being filed jointly by Politan Capital Management GP LLC, a Delaware limited liability company ("Politan Management"), Politan Capital Partners GP LLC, a Delaware limited liability company ("Politan GP"), and Quentin Koffey, a citizen of the United States of America (together with Politan, Politan Management and Politan GP, the "Reporting Persons"), each of whom has the same business address as Politan and may be deemed to have a pecuniary interest in securities reported on this Form 4 (the "Subject Securities").

F4 · ownership.nature: Politan is the investment advisor to certain funds, including Politan Capital Partners LP, a Delaware limited partnership ("Politan LP"), Politan Capital Offshore Partners LP, a Cayman Islands exempted limited partnership ("Politan Offshore"), and Politan Master Fund (collectively with Politan Offshore and Politan LP, the "Politan Funds").

F5 · ownership.nature: Politan, as the investment advisor of the Politan Funds, may be deemed to be the beneficial owner of the Subject Securities for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934. As the general partner of Politan, Politan Management may be deemed to be the beneficial owner of the Subject Securities for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934. As the general partner of the Politan Funds, Politan GP may be deemed to be the beneficial owner of the Subject Securities for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934.

F6 · ownership.nature: By virtue of Mr. Koffey's position as managing partner and chief investment officer of Politan, and as the managing member of Politan Management and Politan GP, Mr. Koffey may be deemed to be the beneficial owner of the Subject Securities for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934. Each of the Reporting Persons disclaims any beneficial ownership of any of the Subject Securities, except to the extent of any pecuniary interest therein.

F7 · ownership.nature: Mr. Koffey is a member of the board of directors of the Issuer of the Subject Securities, and as a result, each of the other Reporting Persons may be directors by deputization for purposes of Section 16 of the Securities Exchange Act of 1934.

SEC source: 0001104659-26-027790 · tm268814d1_4seq1.xml · derivative · entry 1

Politan Capital Management LP · CIK 0001885245 · Director by deputization

Politan Capital Management GP LLC · CIK 0001984176 · Director by deputization

Politan Capital Partners GP LLC · CIK 0001984175 · Director by deputization

Koffey Quentin · CIK 0001984174 · Director by deputization

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 142,681

Underlying: Common Stock · 142,681 shares

Expires not disclosed

F1 · derivative.exercise_price: On March 11, 2026, Politan Capital Partners Master Fund LP, a Cayman Islands exempted limited partnership ("Politan Master Fund"), entered into a forward sale contract (the "March 11 Forward Contract") with a financial institution (the "Counterparty"). The March 11 Forward Contract obligates Politan Master Fund to deliver 142,681 common shares of MASI (the "March 11 Number of Shares") on the maturity date, August 12, 2026, subject to customary adjustments. In exchange, Politan Master Fund will receive an upfront payment of $24,802,095.85 on or around the trade date, which is based on a trade price of $175.48 per share. Politan Master Fund pledged the March 11 Number of Shares under the March 11 Forward Contract to secure its obligations under the transaction, and retained dividend and voting rights in such pledged shares.

F2 · derivative.exercise_price: (continued from footnote 1) In addition, Politan Master Fund may request to increase the March 11 Number of Shares to be delivered by providing the Counterparty with notice (an "Additional Number of Shares Notice") and, if accepted, the details of the updated transaction will be made available by the Counterparty on a notice (an "Adjustment Notice"). The maturity date of the March 11 Forward Contract may be extended one month to September 12, 2026, at the election of Politan Master Fund. Upon maturity, if the March 11 Forward Contract is cash settled the cash settlement price payable by Politan Master Fund will be calculated on the basis of volume weighted average price per share at maturity. Alternatively, if the March 11 Forward Contract is physically settled, Politan Master Fund will deliver the March 11 Number of Shares (together with any additional number of shares listed in any applicable Adjustment Notice) reflecting the total March 11 Number of Shares sold to the Counterparty.

F1 · kind: On March 11, 2026, Politan Capital Partners Master Fund LP, a Cayman Islands exempted limited partnership ("Politan Master Fund"), entered into a forward sale contract (the "March 11 Forward Contract") with a financial institution (the "Counterparty"). The March 11 Forward Contract obligates Politan Master Fund to deliver 142,681 common shares of MASI (the "March 11 Number of Shares") on the maturity date, August 12, 2026, subject to customary adjustments. In exchange, Politan Master Fund will receive an upfront payment of $24,802,095.85 on or around the trade date, which is based on a trade price of $175.48 per share. Politan Master Fund pledged the March 11 Number of Shares under the March 11 Forward Contract to secure its obligations under the transaction, and retained dividend and voting rights in such pledged shares.

F2 · kind: (continued from footnote 1) In addition, Politan Master Fund may request to increase the March 11 Number of Shares to be delivered by providing the Counterparty with notice (an "Additional Number of Shares Notice") and, if accepted, the details of the updated transaction will be made available by the Counterparty on a notice (an "Adjustment Notice"). The maturity date of the March 11 Forward Contract may be extended one month to September 12, 2026, at the election of Politan Master Fund. Upon maturity, if the March 11 Forward Contract is cash settled the cash settlement price payable by Politan Master Fund will be calculated on the basis of volume weighted average price per share at maturity. Alternatively, if the March 11 Forward Contract is physically settled, Politan Master Fund will deliver the March 11 Number of Shares (together with any additional number of shares listed in any applicable Adjustment Notice) reflecting the total March 11 Number of Shares sold to the Counterparty.

F1 · shares: On March 11, 2026, Politan Capital Partners Master Fund LP, a Cayman Islands exempted limited partnership ("Politan Master Fund"), entered into a forward sale contract (the "March 11 Forward Contract") with a financial institution (the "Counterparty"). The March 11 Forward Contract obligates Politan Master Fund to deliver 142,681 common shares of MASI (the "March 11 Number of Shares") on the maturity date, August 12, 2026, subject to customary adjustments. In exchange, Politan Master Fund will receive an upfront payment of $24,802,095.85 on or around the trade date, which is based on a trade price of $175.48 per share. Politan Master Fund pledged the March 11 Number of Shares under the March 11 Forward Contract to secure its obligations under the transaction, and retained dividend and voting rights in such pledged shares.

F2 · shares: (continued from footnote 1) In addition, Politan Master Fund may request to increase the March 11 Number of Shares to be delivered by providing the Counterparty with notice (an "Additional Number of Shares Notice") and, if accepted, the details of the updated transaction will be made available by the Counterparty on a notice (an "Adjustment Notice"). The maturity date of the March 11 Forward Contract may be extended one month to September 12, 2026, at the election of Politan Master Fund. Upon maturity, if the March 11 Forward Contract is cash settled the cash settlement price payable by Politan Master Fund will be calculated on the basis of volume weighted average price per share at maturity. Alternatively, if the March 11 Forward Contract is physically settled, Politan Master Fund will deliver the March 11 Number of Shares (together with any additional number of shares listed in any applicable Adjustment Notice) reflecting the total March 11 Number of Shares sold to the Counterparty.

F1 · price: On March 11, 2026, Politan Capital Partners Master Fund LP, a Cayman Islands exempted limited partnership ("Politan Master Fund"), entered into a forward sale contract (the "March 11 Forward Contract") with a financial institution (the "Counterparty"). The March 11 Forward Contract obligates Politan Master Fund to deliver 142,681 common shares of MASI (the "March 11 Number of Shares") on the maturity date, August 12, 2026, subject to customary adjustments. In exchange, Politan Master Fund will receive an upfront payment of $24,802,095.85 on or around the trade date, which is based on a trade price of $175.48 per share. Politan Master Fund pledged the March 11 Number of Shares under the March 11 Forward Contract to secure its obligations under the transaction, and retained dividend and voting rights in such pledged shares.

F2 · price: (continued from footnote 1) In addition, Politan Master Fund may request to increase the March 11 Number of Shares to be delivered by providing the Counterparty with notice (an "Additional Number of Shares Notice") and, if accepted, the details of the updated transaction will be made available by the Counterparty on a notice (an "Adjustment Notice"). The maturity date of the March 11 Forward Contract may be extended one month to September 12, 2026, at the election of Politan Master Fund. Upon maturity, if the March 11 Forward Contract is cash settled the cash settlement price payable by Politan Master Fund will be calculated on the basis of volume weighted average price per share at maturity. Alternatively, if the March 11 Forward Contract is physically settled, Politan Master Fund will deliver the March 11 Number of Shares (together with any additional number of shares listed in any applicable Adjustment Notice) reflecting the total March 11 Number of Shares sold to the Counterparty.

F1 · derivative.exercise_date: On March 11, 2026, Politan Capital Partners Master Fund LP, a Cayman Islands exempted limited partnership ("Politan Master Fund"), entered into a forward sale contract (the "March 11 Forward Contract") with a financial institution (the "Counterparty"). The March 11 Forward Contract obligates Politan Master Fund to deliver 142,681 common shares of MASI (the "March 11 Number of Shares") on the maturity date, August 12, 2026, subject to customary adjustments. In exchange, Politan Master Fund will receive an upfront payment of $24,802,095.85 on or around the trade date, which is based on a trade price of $175.48 per share. Politan Master Fund pledged the March 11 Number of Shares under the March 11 Forward Contract to secure its obligations under the transaction, and retained dividend and voting rights in such pledged shares.

F2 · derivative.exercise_date: (continued from footnote 1) In addition, Politan Master Fund may request to increase the March 11 Number of Shares to be delivered by providing the Counterparty with notice (an "Additional Number of Shares Notice") and, if accepted, the details of the updated transaction will be made available by the Counterparty on a notice (an "Adjustment Notice"). The maturity date of the March 11 Forward Contract may be extended one month to September 12, 2026, at the election of Politan Master Fund. Upon maturity, if the March 11 Forward Contract is cash settled the cash settlement price payable by Politan Master Fund will be calculated on the basis of volume weighted average price per share at maturity. Alternatively, if the March 11 Forward Contract is physically settled, Politan Master Fund will deliver the March 11 Number of Shares (together with any additional number of shares listed in any applicable Adjustment Notice) reflecting the total March 11 Number of Shares sold to the Counterparty.

F1 · derivative.expiration_date: On March 11, 2026, Politan Capital Partners Master Fund LP, a Cayman Islands exempted limited partnership ("Politan Master Fund"), entered into a forward sale contract (the "March 11 Forward Contract") with a financial institution (the "Counterparty"). The March 11 Forward Contract obligates Politan Master Fund to deliver 142,681 common shares of MASI (the "March 11 Number of Shares") on the maturity date, August 12, 2026, subject to customary adjustments. In exchange, Politan Master Fund will receive an upfront payment of $24,802,095.85 on or around the trade date, which is based on a trade price of $175.48 per share. Politan Master Fund pledged the March 11 Number of Shares under the March 11 Forward Contract to secure its obligations under the transaction, and retained dividend and voting rights in such pledged shares.

F2 · derivative.expiration_date: (continued from footnote 1) In addition, Politan Master Fund may request to increase the March 11 Number of Shares to be delivered by providing the Counterparty with notice (an "Additional Number of Shares Notice") and, if accepted, the details of the updated transaction will be made available by the Counterparty on a notice (an "Adjustment Notice"). The maturity date of the March 11 Forward Contract may be extended one month to September 12, 2026, at the election of Politan Master Fund. Upon maturity, if the March 11 Forward Contract is cash settled the cash settlement price payable by Politan Master Fund will be calculated on the basis of volume weighted average price per share at maturity. Alternatively, if the March 11 Forward Contract is physically settled, Politan Master Fund will deliver the March 11 Number of Shares (together with any additional number of shares listed in any applicable Adjustment Notice) reflecting the total March 11 Number of Shares sold to the Counterparty.

F3 · ownership.nature: In addition to Politan Capital Management LP, a Delaware limited partnership ("Politan"), this Form 4 is being filed jointly by Politan Capital Management GP LLC, a Delaware limited liability company ("Politan Management"), Politan Capital Partners GP LLC, a Delaware limited liability company ("Politan GP"), and Quentin Koffey, a citizen of the United States of America (together with Politan, Politan Management and Politan GP, the "Reporting Persons"), each of whom has the same business address as Politan and may be deemed to have a pecuniary interest in securities reported on this Form 4 (the "Subject Securities").

F4 · ownership.nature: Politan is the investment advisor to certain funds, including Politan Capital Partners LP, a Delaware limited partnership ("Politan LP"), Politan Capital Offshore Partners LP, a Cayman Islands exempted limited partnership ("Politan Offshore"), and Politan Master Fund (collectively with Politan Offshore and Politan LP, the "Politan Funds").

F5 · ownership.nature: Politan, as the investment advisor of the Politan Funds, may be deemed to be the beneficial owner of the Subject Securities for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934. As the general partner of Politan, Politan Management may be deemed to be the beneficial owner of the Subject Securities for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934. As the general partner of the Politan Funds, Politan GP may be deemed to be the beneficial owner of the Subject Securities for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934.

F6 · ownership.nature: By virtue of Mr. Koffey's position as managing partner and chief investment officer of Politan, and as the managing member of Politan Management and Politan GP, Mr. Koffey may be deemed to be the beneficial owner of the Subject Securities for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934. Each of the Reporting Persons disclaims any beneficial ownership of any of the Subject Securities, except to the extent of any pecuniary interest therein.

F7 · ownership.nature: Mr. Koffey is a member of the board of directors of the Issuer of the Subject Securities, and as a result, each of the other Reporting Persons may be directors by deputization for purposes of Section 16 of the Securities Exchange Act of 1934.

SEC source: 0001104659-25-085646 · tm2524450-1_4seq1.xml · nonDerivative · entry 1

Politan Capital Management LP · CIK 0001885245 · Director by deputization

Politan Capital Management GP LLC · CIK 0001984176 · Director by deputization

Politan Capital Partners GP LLC · CIK 0001984175 · Director by deputization

Koffey Quentin · CIK 0001984174 · Director

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 4,589,648

F1 · kind: The Reporting Persons (as defined below) distributed these shares to a limited partner - no shares were sold in the open market or otherwise.

F1 · acquired: The Reporting Persons (as defined below) distributed these shares to a limited partner - no shares were sold in the open market or otherwise.

F2 · ownership.nature: In addition to Politan Capital Management LP, a Delaware limited partnership ("Politan"), this Form 4 is being filed jointly by Politan Capital Management GP LLC, a Delaware limited liability company ("Politan Management"), Politan Capital Partners GP LLC, a Delaware limited liability company ("Politan GP"), and Quentin Koffey, a citizen of the United States of America (together with Politan, Politan Management and Politan GP, the "Reporting Persons"), each of whom has the same business address as Politan and may be deemed to have a pecuniary interest in securities reported on this Form 4 (the "Subject Securities").

F3 · ownership.nature: Politan is the investment advisor to certain funds, including Politan Capital Partners LP, a Delaware limited partnership ("Politan LP"), Politan Capital Offshore Partners LP, a Cayman Islands exempted limited partnership ("Politan Offshore"), and Politan Capital Partners Master Fund LP, a Cayman Islands exempted limited partnership ("Politan Master Fund") (collectively with Politan Offshore and Politan LP, the "Politan Funds").

F4 · ownership.nature: Politan, as the investment advisor of the Politan Funds, may be deemed to be the beneficial owner of the Subject Securities for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934. As the general partner of Politan, Politan Management may be deemed to be the beneficial owner of the Subject Securities for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934. As the general partner of the Politan Funds, Politan GP may be deemed to be the beneficial owner of the Subject Securities for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934.

F5 · ownership.nature: By virtue of Mr. Koffey's position as managing partner and chief investment officer of Politan, and as the managing member of Politan Management and Politan GP, Mr. Koffey may be deemed to be the beneficial owner of the Subject Securities for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934. Each of the Reporting Persons disclaims any beneficial ownership of any of the Subject Securities, except to the extent of any pecuniary interest therein.

F6 · ownership.nature: Mr. Koffey is a member of the board of directors of the Issuer of the Subject Securities, and as a result, each of the other Reporting Persons may be directors by deputization for purposes of Section 16 of the Securities Exchange Act of 1934.

SEC source: 0001104659-25-043642 · tm2513809-1_4seq1.xml · derivative · entry 3

Politan Capital Management LP · CIK 0001885245 · Director by deputization

Politan Capital Management GP LLC · CIK 0001984176 · Director by deputization

Politan Capital Partners GP LLC · CIK 0001984175 · Director by deputization

Koffey Quentin · CIK 0001984174 · Director

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 1,225

Underlying: Common Stock · 1,225 shares

Expires 2035-04-29

F6 · derivative.exercise_price: Each restricted stock unit ("RSU") represents the contingent right to receive one share of Common Stock of the Issuer upon vesting of the RSU.

F9 · derivative.exercise_date: These RSUs were granted on April 29, 2025 and will vest in full on the earlier of the first anniversary of the grant date or the date of the next annual meeting of stockholders following the grant.

F8 · ownership.nature: These RSUs are held directly by Mr. Koffey.

SEC source: 0001104659-25-043642 · tm2513809-1_4seq1.xml · derivative · entry 2

Politan Capital Management LP · CIK 0001885245 · Director by deputization

Politan Capital Management GP LLC · CIK 0001984176 · Director by deputization

Politan Capital Partners GP LLC · CIK 0001984175 · Director by deputization

Koffey Quentin · CIK 0001984174 · Director

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 0

Underlying: Common Stock · 1,790 shares

Expires 2034-09-19

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_price: Each restricted stock unit ("RSU") represents the contingent right to receive one share of Common Stock of the Issuer upon vesting of the RSU.

F7 · derivative.exercise_date: These RSUs were granted on September 19, 2024 and vested in full on April 29, 2025, the date of the next annual meeting of stockholders following the date of the grant.

F8 · ownership.nature: These RSUs are held directly by Mr. Koffey.

SEC source: 0001104659-25-043642 · tm2513809-1_4seq1.xml · nonDerivative · entry 1

Politan Capital Management LP · CIK 0001885245 · Director by deputization

Politan Capital Management GP LLC · CIK 0001984176 · Director by deputization

Politan Capital Partners GP LLC · CIK 0001984175 · Director by deputization

Koffey Quentin · CIK 0001984174 · Director

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 4,716,536

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · ownership.nature: In addition to Politan Capital Management LP, a Delaware limited partnership ("Politan"), this Form 4 is being filed jointly by Politan Capital Management GP LLC, a Delaware limited liability company ("Politan Management"), Politan Capital Partners GP LLC, a Delaware limited liability company ("Politan GP"), and Quentin Koffey, a citizen of the United States of America (together with Politan, Politan Management and Politan GP, the "Reporting Persons"), each of whom has the same business address as Politan and may be deemed to have a pecuniary interest in securities reported on this Form 4 (the "Subject Securities").

F2 · ownership.nature: Politan is the investment advisor to certain funds, including Politan Capital Partners LP, a Delaware limited partnership ("Politan LP"), Politan Capital Offshore Partners LP, a Cayman Islands exempted limited partnership ("Politan Offshore"), and Politan Capital Partners Master Fund LP, a Cayman Islands exempted limited partnership ("Politan Master Fund") (collectively with Politan Offshore and Politan LP, the "Politan Funds").

F3 · ownership.nature: Politan, as the investment advisor of the Politan Funds, may be deemed to be the beneficial owner of the Subject Securities for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934. As the general partner of Politan, Politan Management may be deemed to be the beneficial owner of the Subject Securities for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934. As the general partner of the Politan Funds, Politan GP may be deemed to be the beneficial owner of the Subject Securities for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934.

F4 · ownership.nature: By virtue of Mr. Koffey's position as managing partner and chief investment officer of Politan, and as the managing member of Politan Management and Politan GP, Mr. Koffey may be deemed to be the beneficial owner of the Subject Securities for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934. Each of the Reporting Persons disclaims any beneficial ownership of any of the Subject Securities, except to the extent of any pecuniary interest therein.

F5 · ownership.nature: Mr. Koffey is a member of the board of directors of the Issuer of the Subject Securities, and as a result, each of the other Reporting Persons may be directors by deputization for purposes of Section 16 of the Securities Exchange Act of 1934.

SEC source: 0001104659-24-102153 · tm2424529-1_4seq1.xml · derivative · entry 3

Politan Capital Management LP · CIK 0001885245 · Director by deputization

Politan Capital Management GP LLC · CIK 0001984176 · Director by deputization

Politan Capital Partners GP LLC · CIK 0001984175 · Director by deputization

Koffey Quentin · CIK 0001984174 · Director by deputization

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 1,790

Underlying: Common Stock · 1,790 shares

Expires 2034-09-19

F6 · derivative.exercise_price: Each restricted stock unit ("RSU") represents the contingent right to receive one share of Common Stock of the Issuer upon vesting of the RSU.

F9 · derivative.exercise_date: These RSUs were granted on September 19, 2024 and will vest in full on the earlier of the first anniversary of the grant date or the date of the next annual meeting of stockholders following the grant.

F8 · ownership.nature: These RSUs are held directly by Mr. Koffey.

SEC source: 0001104659-24-102153 · tm2424529-1_4seq1.xml · derivative · entry 2

Politan Capital Management LP · CIK 0001885245 · Director by deputization

Politan Capital Management GP LLC · CIK 0001984176 · Director by deputization

Politan Capital Partners GP LLC · CIK 0001984175 · Director by deputization

Koffey Quentin · CIK 0001984174 · Director by deputization

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 1,228

Underlying: Common Stock · 1,228 shares

Expires 2033-06-25

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_price: Each restricted stock unit ("RSU") represents the contingent right to receive one share of Common Stock of the Issuer upon vesting of the RSU.

F7 · derivative.exercise_date: These RSUs were granted on June 26, 2023 and vested in full on June 26, 2024, the first anniversary of the grant date.

F8 · ownership.nature: These RSUs are held directly by Mr. Koffey.

SEC source: 0001104659-24-102153 · tm2424529-1_4seq1.xml · nonDerivative · entry 1

Politan Capital Management LP · CIK 0001885245 · Director by deputization

Politan Capital Management GP LLC · CIK 0001984176 · Director by deputization

Politan Capital Partners GP LLC · CIK 0001984175 · Director by deputization

Koffey Quentin · CIK 0001984174 · Director by deputization

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 4,714,746

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · ownership.nature: In addition to Politan Capital Management LP, a Delaware limited partnership ("Politan"), this Form 4 is being filed jointly by Politan Capital Management GP LLC, a Delaware limited liability company ("Politan Management"), Politan Capital Partners GP LLC, a Delaware limited liability company ("Politan GP"), and Quentin Koffey, a citizen of the United States of America (together with Politan, Politan Management and Politan GP, the "Reporting Persons"), each of whom has the same business address as Politan and may be deemed to have a pecuniary interest in securities reported on this Form 4 (the "Subject Securities").

F2 · ownership.nature: Politan is the investment advisor to certain funds, including Politan Capital Partners LP, a Delaware limited partnership ("Politan LP"), Politan Capital Offshore Partners LP, a Cayman Islands exempted limited partnership ("Politan Offshore"), and Politan Capital Partners Master Fund LP, a Cayman Islands exempted limited partnership ("Politan Master Fund") (collectively with Politan Offshore and Politan LP, the "Politan Funds").

F3 · ownership.nature: Politan, as the investment advisor of the Politan Funds, may be deemed to be the beneficial owner of the Subject Securities for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934. As the general partner of Politan, Politan Management may be deemed to be the beneficial owner of the Subject Securities for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934. As the general partner of the Politan Funds, Politan GP may be deemed to be the beneficial owner of the Subject Securities for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934.

F4 · ownership.nature: By virtue of Mr. Koffey's position as managing partner and chief investment officer of Politan, and as the managing member of Politan Management and Politan GP, Mr. Koffey may be deemed to be the beneficial owner of the Subject Securities for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934. Each of the Reporting Persons disclaims any beneficial ownership of any of the Subject Securities, except to the extent of any pecuniary interest therein.

F5 · ownership.nature: Mr. Koffey is a member of the board of directors of the Issuer of the Subject Securities, and as a result, each of the other Reporting Persons may be directors by deputization for purposes of Section 16 of the Securities Exchange Act of 1934.

SEC source: 0001104659-23-078707 · tm2320674-2_4seq1.xml · derivative · entry 2

Politan Capital Management LP · CIK 0001885245 · Director by deputization

Politan Capital Management GP LLC · CIK 0001984176 · Director by deputization

Politan Capital Partners GP LLC · CIK 0001984175 · Director by deputization

Koffey Quentin · CIK 0001984174 · Director by deputization

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 1,228

Underlying: Common Stock · 1,228 shares

Expires 2033-06-25

F6 · derivative.exercise_price: Each restricted stock unit ("RSU") represents the contingent right to receive one share of Common Stock of the Issuer upon vesting of the RSU.

F7 · derivative.exercise_date: These RSUs were granted on June 26, 2023 and will vest in full on the earlier of the first anniversary of the grant date or the date of the next annual meeting of stockholders following the grant.

F8 · ownership.nature: These RSUs are held directly by Mr. Koffey.