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person · Reporting owner

Greene Barry E

Disclosed activity across 7 companies

Tapewire entity
36009
SEC CIK
0001291963

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Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
ALNYLAM PHARMACEUTICALS, INC.ALNY · Entity 3132PresidentSeptember 09, 2020September 11, 2020
Acorda Therapeutics, Inc.ACOR · Entity 111987DirectorJune 02, 2021June 04, 2021
BCLS Acquisition Corp.BLSA · Entity 145747DirectorOctober 22, 2020October 22, 2020
CITY THERAPEUTICS, INC.CTY · Entity 184066DirectorOctober 15, 2026October 16, 2026
Dyne Therapeutics, Inc.DYN · Entity 3948DirectorJune 22, 2026June 23, 2026
Karyopharm Therapeutics Inc.KPTI · Entity 781DirectorMay 21, 2026May 26, 2026

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

ALNYLAM PHARMACEUTICALS, INC.

Report date September 09, 2020 · Filed September 11, 2020

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect65,412 Reported balance After 2020-07-16 transaction · row 1 Sequence does not reconcile; account continuity is unresolved.
1 source row

Row 1 · 2020-07-16 · Gift · Acquired 3,176 · Balance 65,412

F1: Represents shares of ALNY common stock distributed upon termination of the Barry E. Greene Qualified Annuity Interest Trust (GRAT), of which the reporting person is the sole Trustee. Upon termination of the trust on July 16, 2020, 155 of the shares held by the GRAT were gifted to a non-dependent child, and 155 of the shares were transferred to the reporting persons dependent child. The remaining 3,176 shares were distributed to the reporting person.

Common StockSEC Table I · non-derivativeDirect114,873 Reported balance After 2020-09-09 transaction · row 2 Sequence does not reconcile; account continuity is unresolved.
1 source row

Row 2 · 2020-09-09 · Exercise / conversion · Acquired 44,530 · Balance 114,873

F2: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 13, 2020. The 44,530 options exercised and sold by the reporting person were due to expire on December 8, 2020.

Common StockSEC Table I · non-derivativeDirect100,798 Reported balance After 2020-09-09 transaction · row 3 Sequence does not reconcile; account continuity is unresolved.
1 source row

Row 3 · 2020-09-09 · Sale · Disposed 14,075 · Balance 100,798

F2: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 13, 2020. The 44,530 options exercised and sold by the reporting person were due to expire on December 8, 2020.

F3: Sale prices ranged from $122.00 to $123.00.

Common StockSEC Table I · non-derivativeDirect73,689 Reported balance After 2020-09-09 transaction · row 4 Sequence does not reconcile; account continuity is unresolved.
1 source row

Row 4 · 2020-09-09 · Sale · Disposed 27,109 · Balance 73,689

F2: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 13, 2020. The 44,530 options exercised and sold by the reporting person were due to expire on December 8, 2020.

F4: Sale prices ranged from $123.01 to $124.00.

Common StockSEC Table I · non-derivativeDirect70,343 Reported balance After 2020-09-09 transaction · row 5 Sequence does not reconcile; account continuity is unresolved.
1 source row

Row 5 · 2020-09-09 · Sale · Disposed 3,346 · Balance 70,343

F2: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 13, 2020. The 44,530 options exercised and sold by the reporting person were due to expire on December 8, 2020.

F5: Sale prices ranged from $124.03 to $124.87.

Common StockSEC Table I · non-derivativeIndirectby Dependent155 Reported balance After 2020-07-16 transaction · row 6 Account identity is unresolved; indirect or unspecified ownership is not merged.
1 source row

Row 6 · 2020-07-16 · Gift · Acquired 155 · Balance 155

F1: Represents shares of ALNY common stock distributed upon termination of the Barry E. Greene Qualified Annuity Interest Trust (GRAT), of which the reporting person is the sole Trustee. Upon termination of the trust on July 16, 2020, 155 of the shares held by the GRAT were gifted to a non-dependent child, and 155 of the shares were transferred to the reporting persons dependent child. The remaining 3,176 shares were distributed to the reporting person.

Common StockSEC Table I · non-derivativeIndirectby Trust3,331 Reported balance After 2020-07-16 transaction · row 7 Account identity is unresolved; indirect or unspecified ownership is not merged.
1 source row

Row 7 · 2020-07-16 · Gift · Disposed 155 · Balance 3,331

F1: Represents shares of ALNY common stock distributed upon termination of the Barry E. Greene Qualified Annuity Interest Trust (GRAT), of which the reporting person is the sole Trustee. Upon termination of the trust on July 16, 2020, 155 of the shares held by the GRAT were gifted to a non-dependent child, and 155 of the shares were transferred to the reporting persons dependent child. The remaining 3,176 shares were distributed to the reporting person.

Common StockSEC Table I · non-derivativeIndirectby Trust3,176 Reported balance After 2020-07-16 transaction · row 8 Account identity is unresolved; indirect or unspecified ownership is not merged.
1 source row

Row 8 · 2020-07-16 · Gift · Disposed 155 · Balance 3,176

F1: Represents shares of ALNY common stock distributed upon termination of the Barry E. Greene Qualified Annuity Interest Trust (GRAT), of which the reporting person is the sole Trustee. Upon termination of the trust on July 16, 2020, 155 of the shares held by the GRAT were gifted to a non-dependent child, and 155 of the shares were transferred to the reporting persons dependent child. The remaining 3,176 shares were distributed to the reporting person.

Common StockSEC Table I · non-derivativeIndirectby Trust0 Reported balance After 2020-07-16 transaction · row 9 Account identity is unresolved; indirect or unspecified ownership is not merged.
1 source row

Row 9 · 2020-07-16 · Gift · Disposed 3,176 · Balance 0

F1: Represents shares of ALNY common stock distributed upon termination of the Barry E. Greene Qualified Annuity Interest Trust (GRAT), of which the reporting person is the sole Trustee. Upon termination of the trust on July 16, 2020, 155 of the shares held by the GRAT were gifted to a non-dependent child, and 155 of the shares were transferred to the reporting persons dependent child. The remaining 3,176 shares were distributed to the reporting person.

Stock Option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $9.14 · Expires 2020-12-08Direct0 Reported balance After 2020-09-09 transaction · row 11 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 11 · 2020-09-09 · Exercise / conversion · Disposed 44,530 · Balance 0

F2: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 13, 2020. The 44,530 options exercised and sold by the reporting person were due to expire on December 8, 2020.

F7: The stock option vested as to 25% of the shares on the 1st anniversary of the date of the stock option grant and as to an additional 6.25% of the shares each successive three month period thereafter.

Common StockSEC Table I · non-derivativeIndirectby Managed Account3,003 Reported balance Holding disclosure · report date 2020-09-09 · row 10 Holding and transaction disclosures are not merged.
1 source row

Row 10 · Balance 3,003

F6: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

Filing footnotes · ownership attribution and instrument terms

F1: Represents shares of ALNY common stock distributed upon termination of the Barry E. Greene Qualified Annuity Interest Trust (GRAT), of which the reporting person is the sole Trustee. Upon termination of the trust on July 16, 2020, 155 of the shares held by the GRAT were gifted to a non-dependent child, and 155 of the shares were transferred to the reporting persons dependent child. The remaining 3,176 shares were distributed to the reporting person.

F2: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 13, 2020. The 44,530 options exercised and sold by the reporting person were due to expire on December 8, 2020.

F3: Sale prices ranged from $122.00 to $123.00.

F4: Sale prices ranged from $123.01 to $124.00.

F5: Sale prices ranged from $124.03 to $124.87.

F6: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

F7: The stock option vested as to 25% of the shares on the 1st anniversary of the date of the stock option grant and as to an additional 6.25% of the shares each successive three month period thereafter.

Acorda Therapeutics, Inc.

Report date June 02, 2021 · Filed June 04, 2021

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Non-Employee Stock OptionSEC Table II · derivative / convertible security · Conversion / exercise price $3.75 · Expires 2031-06-02Direct10,000 Reported balance After 2021-06-02 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2021-06-02 · Grant · Acquired 10,000 · Balance 10,000

F1: The shares subject to this option vest in four equal quarterly installments over 12 months beginning on June 2, 2021, with the first quarterly installment vesting on September 2, 2021.

Filing footnotes · ownership attribution and instrument terms

F1: The shares subject to this option vest in four equal quarterly installments over 12 months beginning on June 2, 2021, with the first quarterly installment vesting on September 2, 2021.

BCLS Acquisition Corp.

Report date October 22, 2020 · Filed October 22, 2020

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Class B ordinary sharesSEC Table II · derivative / convertible securityDirectNot disclosed Reported balance Holding disclosure · report date 2020-10-22 · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · Balance Not disclosed

F1: As described in the issuer's registration statement on Form S-1 (File No. 333-249284) under the heading "Description of Securities--Founder Shares", the shares of Class B ordinary shares, par value $0.0001 per share, will automatically convert into shares of Class A ordinary shares, par value $0.0001 per share, of the issuer at the time of the issuer's initial business combination on a one-for-one basis, subject to adjustment for stock splits, stock dividends, reorganizations, recapitalizations and the like, and certain anti-dilution rights and have no expiration date.

Filing footnotes · ownership attribution and instrument terms

F1: As described in the issuer's registration statement on Form S-1 (File No. 333-249284) under the heading "Description of Securities--Founder Shares", the shares of Class B ordinary shares, par value $0.0001 per share, will automatically convert into shares of Class A ordinary shares, par value $0.0001 per share, of the issuer at the time of the issuer's initial business combination on a one-for-one basis, subject to adjustment for stock splits, stock dividends, reorganizations, recapitalizations and the like, and certain anti-dilution rights and have no expiration date.

CITY THERAPEUTICS, INC.

Report date October 15, 2026 · Filed October 16, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $0.92 · Expires 2034-09-28DirectNot disclosed Reported balance Holding disclosure · report date 2026-10-15 · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · Balance Not disclosed

F1: The shares underlying this option vest in 48 equal monthly installments following September 29, 2024, subject to the Reporting Person's continued service on each such vesting date.

Filing footnotes · ownership attribution and instrument terms

F1: The shares underlying this option vest in 48 equal monthly installments following September 29, 2024, subject to the Reporting Person's continued service on each such vesting date.

Dyne Therapeutics, Inc.

Report date June 22, 2026 · Filed June 23, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Stock option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $20.87 · Expires 2036-06-21Direct57,463 Reported balance After 2026-06-22 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2026-06-22 · Grant · Acquired 57,463 · Balance 57,463

F1: The option was granted on June 22, 2026. The shares underlying the option are scheduled to vest over three years in equal monthly installments through June 22, 2029.

Filing footnotes · ownership attribution and instrument terms

F1: The option was granted on June 22, 2026. The shares underlying the option are scheduled to vest over three years in equal monthly installments through June 22, 2029.

Karyopharm Therapeutics Inc.

Report date May 21, 2026 · Filed May 26, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect16,415 Reported balance After 2026-05-21 transaction · row 1 Account or security details depend on footnotes; rows are not merged.
1 source row

Row 1 · 2026-05-21 · Grant · Acquired 15,508 · Balance 16,415

F1: Represents the award of restricted stock units ("RSUs") pursuant to the Karyopharm Therapeutics Inc. 2022 Equity Incentive Plan, as amended. RSUs convert into Karyopharm Therapeutics Inc. common stock on a one-for-one basis. The RSUs vest 100% on May 21, 2027; however, delivery of the shares is deferred until the earlier of (a) the date of the director's separation from service to Karyopharm Therapeutics Inc. and (b) a change-in-control event.

F2: Amounts reported in this Form 4 reflect the one-for fifteen reverse stock split effected by Karyopharm Therapeutics Inc. on February 25, 2025.

Filing footnotes · ownership attribution and instrument terms

F1: Represents the award of restricted stock units ("RSUs") pursuant to the Karyopharm Therapeutics Inc. 2022 Equity Incentive Plan, as amended. RSUs convert into Karyopharm Therapeutics Inc. common stock on a one-for-one basis. The RSUs vest 100% on May 21, 2027; however, delivery of the shares is deferred until the earlier of (a) the date of the director's separation from service to Karyopharm Therapeutics Inc. and (b) a change-in-control event.

F2: Amounts reported in this Form 4 reflect the one-for fifteen reverse stock split effected by Karyopharm Therapeutics Inc. on February 25, 2025.

Past disclosures · reporting ended (1)

No longer tracked through insider filings. These historical balances do not imply present ownership or a zero position.

Sage Therapeutics, Inc.

Report date July 31, 2025 · Filed July 31, 2025

Section 16 reporting ended · disclosed 2025-07-31. Current position is not established by this disclosure.

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect0 Reported balance After 2025-07-31 transaction · row 1 Sequence does not reconcile; account continuity is unresolved.
1 source row

Row 1 · 2025-07-31 · Other · Disposed 46,940 · Balance 0

F1: This Form 4 reports securities disposed of pursuant to the terms of the Agreement and Plan of Merger (the "Merger Agreement"), dated as of June 13, 2025, among Sage Therapeutics, Inc. (the "Issuer"), Supernus Pharmaceuticals, Inc. ("Parent"), and Saphire, Inc., a wholly owned subsidiary of Parent ("Purchaser"), pursuant to which Purchaser completed a cash tender offer for shares of common stock of the Issuer (each, a "Share") and thereafter merged with and into the Issuer, effective as of July 31, 2025 (the effective time of the merger, the "Effective Time"). At the Effective Time, each issued and outstanding Share was cancelled and converted into the right to receive (i) $8.50 per Share in cash (the "Closing Amount"), plus (ii) one contingent value right ("CVR") per Share, each without interest and subject to the withholding of applicable taxes.

F2: (Continued from footnote 1) Each CVR represents the right to receive up to $3.50 per Share in cash upon the satisfaction of specified milestones, as described in the Form 8-K filed by the Issuer with the Securities and Exchange Commission on June 16, 2025.

Common StockSEC Table I · non-derivativeDirect0 Reported balance After 2025-07-31 transaction · row 2 Sequence does not reconcile; account continuity is unresolved.
1 source row

Row 2 · 2025-07-31 · Disposition to issuer · Disposed 53,229 · Balance 0

F1: This Form 4 reports securities disposed of pursuant to the terms of the Agreement and Plan of Merger (the "Merger Agreement"), dated as of June 13, 2025, among Sage Therapeutics, Inc. (the "Issuer"), Supernus Pharmaceuticals, Inc. ("Parent"), and Saphire, Inc., a wholly owned subsidiary of Parent ("Purchaser"), pursuant to which Purchaser completed a cash tender offer for shares of common stock of the Issuer (each, a "Share") and thereafter merged with and into the Issuer, effective as of July 31, 2025 (the effective time of the merger, the "Effective Time"). At the Effective Time, each issued and outstanding Share was cancelled and converted into the right to receive (i) $8.50 per Share in cash (the "Closing Amount"), plus (ii) one contingent value right ("CVR") per Share, each without interest and subject to the withholding of applicable taxes.

F2: (Continued from footnote 1) Each CVR represents the right to receive up to $3.50 per Share in cash upon the satisfaction of specified milestones, as described in the Form 8-K filed by the Issuer with the Securities and Exchange Commission on June 16, 2025.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $6.97 · Expires 2035-01-16Direct0 Reported balance After 2025-07-31 transaction · row 3 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 3 · 2025-07-31 · Disposition to issuer · Disposed 174,000 · Balance 0

F3: Pursuant to the Merger Agreement, at the Effective Time, each option to purchase Shares (a "Company Option") then outstanding and unexercised, whether or not vested, which had a per Share exercise price less than the Closing Amount was deemed fully vested and cancelled and converted into the right to receive (i) a cash payment (without interest and subject to the withholding of applicable taxes) equal to the product of (a) the excess of the Closing Amount over the per Share exercise price of such Company Option, multiplied by (b) the total number of Shares subject to such Company Option immediately prior to the Effective Time, plus (ii) one CVR for each Share subject to such Company Option immediately prior to the Effective Time. Each Company Option, whether or not vested, which had a per Share exercise price greater than or equal to the Closing Amount was cancelled with no consideration payable in respect thereof.

Filing footnotes · ownership attribution and instrument terms

F1: This Form 4 reports securities disposed of pursuant to the terms of the Agreement and Plan of Merger (the "Merger Agreement"), dated as of June 13, 2025, among Sage Therapeutics, Inc. (the "Issuer"), Supernus Pharmaceuticals, Inc. ("Parent"), and Saphire, Inc., a wholly owned subsidiary of Parent ("Purchaser"), pursuant to which Purchaser completed a cash tender offer for shares of common stock of the Issuer (each, a "Share") and thereafter merged with and into the Issuer, effective as of July 31, 2025 (the effective time of the merger, the "Effective Time"). At the Effective Time, each issued and outstanding Share was cancelled and converted into the right to receive (i) $8.50 per Share in cash (the "Closing Amount"), plus (ii) one contingent value right ("CVR") per Share, each without interest and subject to the withholding of applicable taxes.

F2: (Continued from footnote 1) Each CVR represents the right to receive up to $3.50 per Share in cash upon the satisfaction of specified milestones, as described in the Form 8-K filed by the Issuer with the Securities and Exchange Commission on June 16, 2025.

F3: Pursuant to the Merger Agreement, at the Effective Time, each option to purchase Shares (a "Company Option") then outstanding and unexercised, whether or not vested, which had a per Share exercise price less than the Closing Amount was deemed fully vested and cancelled and converted into the right to receive (i) a cash payment (without interest and subject to the withholding of applicable taxes) equal to the product of (a) the excess of the Closing Amount over the per Share exercise price of such Company Option, multiplied by (b) the total number of Shares subject to such Company Option immediately prior to the Effective Time, plus (ii) one CVR for each Share subject to such Company Option immediately prior to the Effective Time. Each Company Option, whether or not vested, which had a per Share exercise price greater than or equal to the Closing Amount was cancelled with no consideration payable in respect thereof.

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
May 06, 2020 Filed May 7, 2020 20:09 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 Exercise / conversionStock Option (right to buy) · Derivative 22,265 $0.00 Strike: $9.14 $0.00
Disclosure

SEC source: 0001735276-20-000060 · edgardoc.xml · derivative · entry 5

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 66,795

Underlying: Common Stock · 22,265 shares

Expires 2020-12-08

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 13, 2020. The 22,265 options exercised and sold by the reporting person were due to expire on December 8, 2020.

F4 · derivative.exercise_date: The stock option vests as to 25% of the shares on the 1st anniversary of the date of the stock option grant and as to an additional 6.25% of the shares each successive three month period thereafter.

Read SEC document
May 06, 2020 Filed May 7, 2020 20:09 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 SaleCommon Stock 22,265 $149.99 $3,339,527.35
Disclosure

SEC source: 0001735276-20-000060 · edgardoc.xml · nonDerivative · entry 2

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 62,236

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 13, 2020. The 22,265 options exercised and sold by the reporting person were due to expire on December 8, 2020.

Read SEC document
May 06, 2020 Filed May 7, 2020 20:09 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 Exercise / conversionCommon Stock 22,265 $9.14 $203,502.10
Disclosure

SEC source: 0001735276-20-000060 · edgardoc.xml · nonDerivative · entry 1

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 84,501

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 13, 2020. The 22,265 options exercised and sold by the reporting person were due to expire on December 8, 2020.

Read SEC document
April 07, 2020 Filed Apr 9, 2020 20:06 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 Tax withholdingCommon Stock 64 $106.65 $6,825.60
Disclosure

SEC source: 0001735276-20-000049 · edgardoc.xml · nonDerivative · entry 3

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 62,236

F2 · kind: Represents shares automatically sold by the Company on behalf of the reporting person pursuant to a mandatory sell-to-cover provision in the PSU award agreement required to cover minimum statutory tax withholding obligations that became due upon the vesting event.

Read SEC document
April 07, 2020 Filed Apr 9, 2020 20:06 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 Tax withholdingCommon Stock 1,599 $104.75 $167,495.25
Disclosure

SEC source: 0001735276-20-000049 · edgardoc.xml · nonDerivative · entry 2

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 62,300

F2 · kind: Represents shares automatically sold by the Company on behalf of the reporting person pursuant to a mandatory sell-to-cover provision in the PSU award agreement required to cover minimum statutory tax withholding obligations that became due upon the vesting event.

Read SEC document
April 07, 2020 Filed Apr 9, 2020 20:06 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 GrantCommon Stock 5,417 $0.00 $0.00
Disclosure

SEC source: 0001735276-20-000049 · edgardoc.xml · nonDerivative · entry 1

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 63,899

F1 · kind: On February 28, 2019, the reporting person was granted performance-based restricted stock units (PSU) in connection with the 2018 year-end compensation review. This PSU award vests in three equal installments upon the later of one year from the date of grant and the achievement of each of three specific clinical development, regulatory or commercial events. One third of the shares subject to release under the PSU award vested upon the filing by the Company of its fourth NDA with the FDA, as determined by the compensation committee of the Company effective April 7, 2020.

Read SEC document
March 13, 2020 Filed Mar 17, 2020 21:35 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 Exercise / conversionStock Option (right to buy) · Derivative 3,030 $0.00 Strike: $0.03 $0.00
Disclosure

SEC source: 0001209191-20-019709 · doc4.xml · derivative · entry 2

Greene Barry E · CIK 0001291963 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 3,030 shares

Expires 2021-04-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: This option representing a right to purchase a specified number of shares vested as to 25% of the shares on April 14, 2012, and the remaining 75% vested in 36 equal monthly installments thereafter.

Read SEC document
March 13, 2020 Filed Mar 17, 2020 21:35 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 Exercise / conversionCommon Stock 3,030 $0.03 $99.99
Disclosure

SEC source: 0001209191-20-019709 · doc4.xml · nonDerivative · entry 1

Greene Barry E · CIK 0001291963 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,030

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 26, 2020 Filed Feb 28, 2020 21:06 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 GrantStock Option (right to buy) · Derivative 29,925 $0.00 Strike: $118.05 $0.00
Disclosure

SEC source: 0001735276-20-000029 · edgardoc.xml · derivative · entry 1

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,925

Underlying: Common Stock · 29,925 shares

Expires 2030-02-25

F1 · shares: Represents the time-vested stock option portion of the reporting person's Annual Equity Award for 2019. The reporting person also received 16,519 performance stock units that will vest upon the achievement of three specific performance conditions, which will be reported on a Form 4 if and when each performance condition is met and the performance stock units vest.

F2 · derivative.exercise_date: The stock option vests as to 25% of the shares on the 1st anniversary of the date of the stock option grant and as to an additional 6.25% of the shares each successive three month period thereafter.

Read SEC document
December 23, 2019 Filed Dec 26, 2019 21:02 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 GrantPerformance Stock Option 2017 (right to buy) · Derivative 9,999 $0.00 Strike: $119.13 $0.00
Disclosure

SEC source: 0001735276-19-000119 · edgardoc.xml · derivative · entry 1

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,998

Underlying: Common Stock · 9,999 shares

Expires 2028-03-01

F1 · kind: On March 1, 2018, the reporting person was granted a performance based stock option to purchase shares of ALNY common stock. One third of the shares subject to the option vest upon the achievement of each of three specific clinical development, regulatory or commercial events, as approved by our compensation committee. The compensation committee of the Company determined that the second performance criterion was met and the option vested as to the second one third of the shares as of December 23, 2019.

Read SEC document
November 22, 2019 Filed Nov 26, 2019 21:08 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 GrantPerformance Stock Option 2017 (right to buy) · Derivative 9,999 $0.00 Strike: $119.13 $0.00
Disclosure

SEC source: 0001735276-19-000110 · edgardoc.xml · derivative · entry 1

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,999

Underlying: Common Stock · 9,999 shares

Expires 2028-03-01

F1 · kind: On March 1, 2018, the reporting person was granted a performance based stock option to purchase shares of ALNY common stock. One third of the shares subject to the option vest upon the achievement of each of three specific clinical development, regulatory or commercial events, as approved by our compensation committee. The compensation committee of the Company determined that the first performance criterion was met on November 22, 2019 and the option vested as to the first one third of the shares as of such date.

Read SEC document
October 23, 2019 Filed Oct 24, 2019 20:04 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 OtherCommon Stock 5,544 $0.00 $0.00
Disclosure

SEC source: 0001735276-19-000094 · edgardoc.xml · nonDerivative · entry 4

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Indirect · by Trust

Disclosed balance after: 3,486

F2 · kind: These shares were distributed in October 2019 to the reporting person from the "Barry E. Greene Qualified Annuity Interest Trust" (GRAT).

F3 · ownership.nature: Represents remaining shares held by the "Barry E. Greene Qualified Annuity Interest Trust" (GRAT), of which Barry E. Greene is the sole Trustee

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October 23, 2019 Filed Oct 24, 2019 20:04 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 OtherCommon Stock 5,544 $0.00 $0.00
Disclosure

SEC source: 0001735276-19-000094 · edgardoc.xml · nonDerivative · entry 3

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 58,482

F2 · kind: These shares were distributed in October 2019 to the reporting person from the "Barry E. Greene Qualified Annuity Interest Trust" (GRAT).

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October 22, 2019 Filed Oct 24, 2019 20:04 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 Exercise / conversionStock Option (right to buy) · Derivative 58,913 $0.00 Strike: $16.43 $0.00
Disclosure

SEC source: 0001735276-19-000094 · edgardoc.xml · derivative · entry 6

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 58,913 shares

Expires 2019-12-09

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 14, 2019. The 58,913 options exercised and sold by the reporting person were due to expire on December 9, 2019.

F5 · derivative.exercise_date: The stock option vests as to 25% of the shares on the 1st anniversary of the date of the stock option grant and as to an additional 6.25% of the shares each successive three month period thereafter.

Read SEC document
October 22, 2019 Filed Oct 24, 2019 20:04 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 SaleCommon Stock 58,913 $89.99 $5,301,580.87
Disclosure

SEC source: 0001735276-19-000094 · edgardoc.xml · nonDerivative · entry 2

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 52,938

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 14, 2019. The 58,913 options exercised and sold by the reporting person were due to expire on December 9, 2019.

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October 22, 2019 Filed Oct 24, 2019 20:04 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 Exercise / conversionCommon Stock 58,913 $16.43 $967,940.59
Disclosure

SEC source: 0001735276-19-000094 · edgardoc.xml · nonDerivative · entry 1

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 111,851

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 14, 2019. The 58,913 options exercised and sold by the reporting person were due to expire on December 9, 2019.

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August 06, 2019 Filed Aug 7, 2019 20:16 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 GrantPerformance Stock Option 2016 (right to buy) · Derivative 6,250 $0.00 Strike: $42.22 $0.00
Disclosure

SEC source: 0001735276-19-000084 · edgardoc.xml · derivative · entry 5

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,000

Underlying: Common Stock · 6,250 shares

Expires 2026-12-20

F4 · kind: On December 20, 2016, the reporting person was granted a performance based stock option to purchase shares of ALNY common stock. One quarter of the shares subject to the option vested upon the achievement of each of four specific clinical development, regulatory or commercial events, as approved by our compensation committee. The compensation committee of the Company determined that the fourth performance criterion was met effective as of August 6, 2019 and the option vested as to the final one-quarter of the shares as of such date.

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August 06, 2019 Filed Aug 7, 2019 20:16 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 GrantPerformance Stock Option 2015 (right to buy) · Derivative 10,000 $88.95 Strike: $88.95 $889,500.00
Disclosure

SEC source: 0001735276-19-000084 · edgardoc.xml · derivative · entry 4

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,000

Underlying: Common Stock · 10,000 shares

Expires 2025-12-18

F3 · kind: On December 18, 2015, the reporting person was granted a performance based stock option to purchase shares of ALNY common stock. One quarter of the shares subject to the option vested upon the achievement of each of four specific clinical development or commercial events, as approved by our compensation committee. The compensation committee of the Company determined that the fourth performance criterion was met effective as of August 6, 2019 and the option vested as to the final one-quarter of the shares as of such date.

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July 11, 2019 Filed Aug 7, 2019 20:16 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 OtherCommon Stock 46 $0.00 $0.00
Disclosure

SEC source: 0001735276-19-000084 · edgardoc.xml · nonDerivative · entry 1

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Indirect · by Managed Account

Disclosed balance after: 3,003

F1 · kind: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

F1 · price: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

F1 · ownership.nature: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

Read SEC document
June 19, 2019 Filed Jun 21, 2019 07:52 UTC Acorda Therapeutics, Inc. ACOR · Entity 111987 GrantNon-Employee Stock Option · Derivative 15,000 $0.00 Strike: $7.54 $0.00
Disclosure

SEC source: 0001209191-19-038362 · doc4.xml · derivative · entry 1

Greene Barry E · CIK 0001291963 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 15,000 shares

Expires 2029-06-19

F1 · derivative.exercise_date: The shares subject to this option vest in four equal quarterly installments over 12 months beginning on June 19, 2019, with the first quarterly installment vesting on September 19, 2019.

Read SEC document
June 06, 2019 Filed Jun 7, 2019 12:57 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 GrantNonstatutory Stock Option (right to buy) · Derivative 25,000 $0.00 Strike: $5.43 $0.00
Disclosure

SEC source: 0001209191-19-035376 · doc4.xml · derivative · entry 1

Greene Barry E · CIK 0001291963 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,000

Underlying: Common Stock · 25,000 shares

Expires 2029-06-05

F1 · derivative.exercise_date: This option vests as to 100% of the underlying shares on June 6, 2020, provided that the reporting person continues to serve as a director of the issuer through such date.

Read SEC document
June 05, 2019 Filed Jun 7, 2019 20:04 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 GrantPerformance Stock Option 2016 (right to buy) · Derivative 6,250 $0.00 Strike: $42.22 $0.00
Disclosure

SEC source: 0001735276-19-000046 · edgardoc.xml · derivative · entry 5

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,750

Underlying: Common Stock · 6,250 shares

Expires 2026-12-20

F3 · kind: On December 20, 2016, the reporting person was granted a performance based stock option to purchase shares of ALNY common stock. One quarter of the shares subject to the option will vest upon the achievement of each of four specific clinical development, regulatory or commercial events, as approved by our compensation committee. On June 6, 2019, the compensation committee of the Company determined the third performance criterion had been met on June 5, 2019 and the option vested as to one-quarter of the shares as of such date.

Read SEC document
April 09, 2019 Filed Jun 7, 2019 20:04 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 OtherCommon Stock 52 $0.00 $0.00
Disclosure

SEC source: 0001735276-19-000046 · edgardoc.xml · nonDerivative · entry 2

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Indirect · by Managed Account

Disclosed balance after: 2,957

F1 · kind: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

F1 · price: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

F1 · ownership.nature: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

Read SEC document
February 28, 2019 Filed Mar 1, 2019 23:10 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 GrantStock Option (right to buy) · Derivative 32,500 $0.00 Strike: $85.00 $0.00
Disclosure

SEC source: 0001735276-19-000034 · edgardoc.xml · derivative · entry 1

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,500

Underlying: Common Stock · 32,500 shares

Expires 2029-02-27

F1 · shares: Represents the time-vested portion of the reporting person's Annual Stock Option Award for 2018. The reporting person also received 16,250 performance stock units that will vest upon the achievement of three specific performance conditions, which will be reported on a Form 4 if and when each performance condition is met and the option vests.

F2 · derivative.exercise_date: The stock option vests as to 25% of the shares on the 1st anniversary of the date of the stock option grant and as to an additional 6.25% of the shares each successive three month period thereafter.

Read SEC document
October 18, 2018 Filed Jun 7, 2019 20:04 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 OtherCommon Stock 21 $0.00 $0.00
Disclosure

SEC source: 0001735276-19-000046 · edgardoc.xml · nonDerivative · entry 1

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Indirect · by Managed Account

Disclosed balance after: 2,905

F1 · kind: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

F1 · price: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

F1 · ownership.nature: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

Read SEC document
September 27, 2018 Filed Sep 28, 2018 20:54 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 GrantPerformance Stock Option 2016 (right to buy) · Derivative 6,250 $0.00 Strike: $42.22 $0.00
Disclosure

SEC source: 0001735276-18-000071 · edgardoc.xml · derivative · entry 2

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,500

Underlying: Common Stock · 6,250 shares

Expires 2026-12-20

F2 · kind: On December 20, 2016, the reporting person was granted a performance based stock option to purchase shares of ALNY common stock. One quarter of the shares subject to the option will vest upon the achievement of each of four specific clinical development, regulatory or commercial events, as approved by our compensation committee. Effective September 27, 2018, the compensation committee of the Company determined the second performance criterion had been met and the option vested as to one-quarter of the shares.

Read SEC document
September 27, 2018 Filed Sep 28, 2018 20:54 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 GrantPerformance Stock Option 2015 (right to buy) · Derivative 10,000 $0.00 Strike: $88.95 $0.00
Disclosure

SEC source: 0001735276-18-000071 · edgardoc.xml · derivative · entry 1

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,000

Underlying: Common Stock · 10,000 shares

Expires 2025-12-18

F1 · kind: On December 18, 2015, the reporting person was granted a performance based stock option to purchase shares of ALNY common stock. One quarter of the shares subject to the option will vest upon the achievement of each of four specific clinical development and regulatory events, as approved by our compensation committee. Effective September 27, 2018, the compensation committee of the Company determined the third performance criterion had been met and the option vested as to one-quarter of the shares.

Read SEC document
August 21, 2018 Filed Aug 23, 2018 20:15 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 GrantPerformance Stock Option 2015 (right to buy) · Derivative 10,000 $0.00 Strike: $88.95 $0.00
Disclosure

SEC source: 0001735276-18-000061 · edgardoc.xml · derivative · entry 1

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,000

Underlying: Common Stock · 10,000 shares

Expires 2025-12-18

F1 · kind: On December 18, 2015, the reporting person was granted a performance based stock option to purchase shares of ALNY common stock. One quarter of the shares subject to the option will vest upon the achievement of each of four specific clinical development or commercial events, as approved by our compensation committee. Effective August 21, 2018, the compensation committee of the Company determined the second performance criterion had been met and the option vested as to one-quarter of the shares.

Read SEC document
August 10, 2018 Filed Aug 14, 2018 23:14 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 GrantPerformance Based Stock Option 2014 (right to buy) · Derivative 15,875 $0.00 Strike: $96.45 $0.00
Disclosure

SEC source: 0001325812-18-000031 · primary_doc.xml · derivative · entry 7

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 47,625

Underlying: Common Stock · 15,875 shares

Expires 2024-12-17

F4 · kind: On December 17, 2014, the reporting person was granted a performance based stock option to purchase shares of ALNY Common Stock. One-third of the shares subject to the option will vest upon the achievement of each of three specific clinical development and regulatory events, as approved by our compensation committee. Effective August 10, 2018, the compensation committee of the Company determined the final performance criteria had been met and the option vested as to the final third of the award

Read SEC document
August 10, 2018 Filed Aug 14, 2018 23:14 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 GrantPerformance Based Stock Option 2013 (right to buy) · Derivative 15,000 $0.00 Strike: $63.00 $0.00
Disclosure

SEC source: 0001325812-18-000031 · primary_doc.xml · derivative · entry 6

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,000

Underlying: Common Stock · 15,000 shares

Expires 2023-12-18

F3 · kind: On December 18, 2013, the reporting person was granted a performance based stock option to purchase shares of ALNY Common Stock. One-third of the shares subject to the option will vest upon the achievement of each of three specific clinical development and regulatory events, as approved by our compensation committee. Effective August 10, 2018, the compensation committee of the Company determined the final performance criteria had been met and the option will vest as to the final third of the award.

Read SEC document
July 31, 2018 Filed Aug 14, 2018 23:14 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 GiftCommon Stock 9,030 $0.00 $0.00
Disclosure

SEC source: 0001325812-18-000031 · primary_doc.xml · nonDerivative · entry 5

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Indirect · by Trust

Disclosed balance after: 9,030

F2 · ownership.nature: The 9,030 shares were previously reported as directly beneficially owned. On 7/31/2018, the shares were contributed to the "Barry E. Greene Qualified Annuity Interest Trust" (GRAT). Barry E. Greene is the sole trustee.

Read SEC document
July 31, 2018 Filed Aug 14, 2018 23:14 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 GiftCommon Stock 9,030 $0.00 $0.00
Disclosure

SEC source: 0001325812-18-000031 · primary_doc.xml · nonDerivative · entry 1

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 52,938

Read SEC document
July 10, 2018 Filed Aug 14, 2018 23:14 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 OtherCommon Stock 29 $0.00 $0.00
Disclosure

SEC source: 0001325812-18-000031 · primary_doc.xml · nonDerivative · entry 4

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Indirect · by Managed Account

Disclosed balance after: 2,884

F1 · kind: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

F1 · price: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

F1 · ownership.nature: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

Read SEC document
June 27, 2018 Filed Jun 29, 2018 07:42 UTC Acorda Therapeutics, Inc. ACOR · Entity 111987 GrantNon-Employee Stock Option · Derivative 15,000 $0.00 Strike: $28.15 $0.00
Disclosure

SEC source: 0001209191-18-039989 · doc4.xml · derivative · entry 1

Greene Barry E · CIK 0001291963 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 15,000 shares

Expires 2028-06-27

F1 · derivative.exercise_date: The shares subject to this option vest in four equal quarterly installments over 12 months beginning on June 27, 2018, with the first quarterly installment vesting on September 27, 2018.

Read SEC document
June 19, 2018 Filed Jun 20, 2018 20:15 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 GrantNonstatutory Stock Option (right to buy) · Derivative 17,000 $0.00 Strike: $18.80 $0.00
Disclosure

SEC source: 0001209191-18-038757 · doc4.xml · derivative · entry 1

Greene Barry E · CIK 0001291963 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,000

Underlying: Common Stock · 17,000 shares

Expires 2028-06-18

F1 · derivative.exercise_date: This option vests as to 100% of the underlying shares on June 19, 2019, provided that the reporting person continues to serve as a director of the issuer through such date.

Read SEC document
May 21, 2018 Filed May 23, 2018 07:35 UTC Acorda Therapeutics, Inc. ACOR · Entity 111987 Exercise / conversionNon-Employee Stock Option · Derivative 10,000 $0.00 Strike: $20.16 $0.00
Disclosure

SEC source: 0001209191-18-032493 · doc4.xml · derivative · entry 3

Greene Barry E · CIK 0001291963 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 10,000 shares

Expires 2018-05-21

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: The exercised options were scheduled to expire in 2018 on the expiration date reported within Table II unless exercised.

F2 · derivative.exercise_date: The shares subject to these options vested in installments and were fully vested on 5/21/2009.

Read SEC document
May 21, 2018 Filed May 23, 2018 07:35 UTC Acorda Therapeutics, Inc. ACOR · Entity 111987 Tax withholdingCommon Stock 8,727 $23.10 $201,593.70
Disclosure

SEC source: 0001209191-18-032493 · doc4.xml · nonDerivative · entry 2

Greene Barry E · CIK 0001291963 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,273

Read SEC document
May 21, 2018 Filed May 23, 2018 07:35 UTC Acorda Therapeutics, Inc. ACOR · Entity 111987 Exercise / conversionCommon Stock 10,000 $20.16 $201,600.00
Disclosure

SEC source: 0001209191-18-032493 · doc4.xml · nonDerivative · entry 1

Greene Barry E · CIK 0001291963 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: The exercised options were scheduled to expire in 2018 on the expiration date reported within Table II unless exercised.

Read SEC document
April 16, 2018 Filed Aug 14, 2018 23:14 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 OtherCommon Stock 28 $0.00 $0.00
Disclosure

SEC source: 0001325812-18-000031 · primary_doc.xml · nonDerivative · entry 3

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Indirect · by Managed Account

Disclosed balance after: 2,855

F1 · kind: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

F1 · price: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

F1 · ownership.nature: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

Read SEC document
March 14, 2018 Filed Mar 16, 2018 21:05 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 SaleCommon Stock 1,300 $145.41 $189,033.00
Disclosure

SEC source: 0001553878-18-000026 · edgardoc.xml · nonDerivative · entry 6

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 61,968

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 11, 2018.

F7 · price: Sale prices ranged from $145.16 to $145.79

Read SEC document
March 14, 2018 Filed Mar 16, 2018 21:05 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 SaleCommon Stock 9,165 $144.67 $1,325,900.55
Disclosure

SEC source: 0001553878-18-000026 · edgardoc.xml · nonDerivative · entry 5

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 63,268

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 11, 2018.

F6 · price: Sale prices ranged from $144.14 to $145.13

Read SEC document
March 14, 2018 Filed Mar 16, 2018 21:05 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 SaleCommon Stock 8,644 $143.58 $1,241,105.52
Disclosure

SEC source: 0001553878-18-000026 · edgardoc.xml · nonDerivative · entry 4

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 72,433

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 11, 2018.

F5 · price: Sale prices ranged from $143.12 to $144.11

Read SEC document
March 14, 2018 Filed Mar 16, 2018 21:05 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 SaleCommon Stock 9,217 $142.68 $1,315,081.56
Disclosure

SEC source: 0001553878-18-000026 · edgardoc.xml · nonDerivative · entry 3

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 81,077

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 11, 2018.

F4 · price: Sale prices ranged from $142.12 to $143.11

Read SEC document
March 14, 2018 Filed Mar 16, 2018 21:05 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 SaleCommon Stock 7,250 $141.74 $1,027,615.00
Disclosure

SEC source: 0001553878-18-000026 · edgardoc.xml · nonDerivative · entry 2

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 90,294

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 11, 2018.

F3 · price: Sale prices ranged from $141.12 to $142.10

Read SEC document
March 14, 2018 Filed Mar 16, 2018 21:05 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 SaleCommon Stock 2,884 $140.43 $405,000.12
Disclosure

SEC source: 0001553878-18-000026 · edgardoc.xml · nonDerivative · entry 1

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 97,544

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 11, 2018.

F2 · price: Sale prices ranged from $140.00 to $140.95

Read SEC document
March 01, 2018 Filed Mar 5, 2018 22:48 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 GrantStock Option (right to buy) · Derivative 30,000 $0.00 Strike: $119.13 $0.00
Disclosure

SEC source: 0001553878-18-000009 · edgardoc.xml · derivative · entry 1

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,000

Underlying: Common Stock · 30,000 shares

Expires 2028-02-28

F1 · shares: Represents the time-vested portion of the reporting person's Annual Stock Option Award for 2017. The reporting person also received 30,000 options to purchase shares of ALNY common stock that will vest upon the achievement of three specific performance conditions, which will be reported on a Form 4 if and when each performance condition is met and the option vests.

F2 · derivative.exercise_date: The stock option vests as to 25% of the shares on the 1st anniversary of the date of the stock option grant and as to the remaining shares ratably at the end of each three-month period thereafter over the following thirty-three (33) months

Read SEC document
January 17, 2018 Filed Aug 14, 2018 23:14 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 OtherCommon Stock 17 $0.00 $0.00
Disclosure

SEC source: 0001325812-18-000031 · primary_doc.xml · nonDerivative · entry 2

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Indirect · by Managed Account

Disclosed balance after: 2,827

F1 · kind: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

F1 · price: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

F1 · ownership.nature: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

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December 20, 2017 Filed Dec 21, 2017 21:37 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 GrantPerformance Stock Option 2016 (right to buy) · Derivative 6,250 $0.00 Strike: $42.22 $0.00
Disclosure

SEC source: 0001325812-17-000036 · edgardoc.xml · derivative · entry 1

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,250

Underlying: Common Stock · 6,250 shares

Expires 2026-12-20

F1 · kind: On December 20, 2016, the reporting person was granted a performance based stock option to purchase shares of ALNY common stock. One quarter of the shares subject to the option will vest upon the achievement of each of four specific clinical development, regulatory or commercial events, as approved by our compensation committee. Effective December 20, 2017, the compensation committee of the Company determined the first performance criterion had been met and the option vested as to one-quarter of the shares.

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November 06, 2017 Filed Nov 8, 2017 22:25 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 GrantPerformance Stock Option 2015 (right to buy) · Derivative 10,000 $0.00 Strike: $88.95 $0.00
Disclosure

SEC source: 0001553878-17-000063 · edgardoc.xml · derivative · entry 1

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Common Stock · 10,000 shares

Expires 2025-12-18

F1 · kind: On December 18, 2015, the reporting person was granted a performance based stock option to purchase shares of ALNY common stock. One quarter of the shares subject to the option will vest upon the achievement of each of four specific clinical development and regulatory events, as approved by our compensation committee. Effective November 6, 2017, the compensation committee of the Company determined the first performance criterion had been met and the option vested as to one-quarter of the shares.

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October 02, 2017 Filed Oct 4, 2017 23:45 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 Exercise / conversionStock Option (Right to Buy) · Derivative 85,316 $0.00 Strike: $21.35 $0.00
Disclosure

SEC source: 0001553878-17-000054 · primary_doc.xml · derivative · entry 4

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 85,316 shares

Expires 2018-12-08

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sale reported on this Form 4 was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 23, 2017.

F3 · derivative.exercise_date: The stock option vested as to 25% of the shares on the first anniversary of the grant date and as to an additional 6.25% of the shares each successive three month period thereafter.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.