PYOTT DAVID E I

SEC source: 0001051578-26-000010 · wk-form4_1789678066.xml · derivative · entry 2

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 605

Underlying: Common Stock · 201 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Each RSU represents a contingent right to receive one share of the Company's common stock.

F4 · derivative.exercise_date: RSUs granted in connection with the Reporting Person's service as a non-employee director as of the Company's 2026 annual meeting of stockholders. The RSUs vest in equal installments on 9/15/2026, 12/15/2026, 3/15/2027 and 6/15/2027, subject to the non-employee director's continuous service.

F4 · derivative.expiration_date: RSUs granted in connection with the Reporting Person's service as a non-employee director as of the Company's 2026 annual meeting of stockholders. The RSUs vest in equal installments on 9/15/2026, 12/15/2026, 3/15/2027 and 6/15/2027, subject to the non-employee director's continuous service.

SEC source: 0001051578-26-000010 · wk-form4_1789678066.xml · nonDerivative · entry 1

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · By the David E.I. Pyott Trust

Disclosed balance after: 9,575

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: The shares were issued pursuant to settlement of vested Restricted Stock Units ("RSUs"). Each RSU represents a contingent right to receive one share of the Company's common stock.

F2 · balance_after: Includes 1,383 shares previously owned directly that were transferred to the reporting person's trust on May 14, 2026. There was no change in the reporting person's pecuniary interest in the shares.

SEC source: 0001051578-26-000008 · wk-form4_1782765056.xml · derivative · entry 3

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 806

Underlying: Common Stock · 806 shares

Expires not disclosed

F2 · derivative.exercise_price: Each Restricted Stock Unit ("RSU") represents a contingent right to receive one share of the Company's common stock.

F4 · derivative.exercise_date: RSUs granted in connection with the Reporting Person's service as a non-employee director as of the Company's 2026 annual meeting of stockholders. The RSUs vest in equal installments on 9/15/2026, 12/15/2026, 3/15/2027 and 6/15/2027, subject to the non-employee director's continuous service.

F4 · derivative.expiration_date: RSUs granted in connection with the Reporting Person's service as a non-employee director as of the Company's 2026 annual meeting of stockholders. The RSUs vest in equal installments on 9/15/2026, 12/15/2026, 3/15/2027 and 6/15/2027, subject to the non-employee director's continuous service.

SEC source: 0001051578-26-000008 · wk-form4_1782765056.xml · derivative · entry 2

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,417

Underlying: Common Stock · 2,417 shares

Expires not disclosed

F2 · derivative.exercise_price: Each Restricted Stock Unit ("RSU") represents a contingent right to receive one share of the Company's common stock.

F3 · derivative.exercise_date: RSUs granted in connection with the Reporting Person's service as a non-employee director as of the Company's 2026 annual meeting of stockholders. The RSUs vest in full on the one-year anniversary of the date of grant, subject to the non-employee director's continuous service.

F3 · derivative.expiration_date: RSUs granted in connection with the Reporting Person's service as a non-employee director as of the Company's 2026 annual meeting of stockholders. The RSUs vest in full on the one-year anniversary of the date of grant, subject to the non-employee director's continuous service.

SEC source: 0001051578-26-000008 · wk-form4_1782765056.xml · derivative · entry 1

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 3,837

Underlying: Common Stock · 3,837 shares

Expires 2036-06-24

F1 · derivative.exercise_date: Annual option granted in connection with the Reporting Person's service as a non-employee director as of the Company's 2026 annual meeting of stockholders. The option will vest in full on the one-year anniversary of the date of grant, subject to the non-employee director's continuous service.

SEC source: 0001178670-26-000048 · form4.xml · derivative · entry 8

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 3,830 shares

Expires 2026-06-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on November 12, 2025. The options exercised by the reporting person were due to expire on June 3, 2026.

F7 · derivative.exercise_date: This stock option was fully vested and exercisable as of June 3, 2017.

SEC source: 0001178670-26-000048 · form4.xml · nonDerivative · entry 6

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,582

F1 · kind: The transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on November 12, 2025. The options exercised by the reporting person were due to expire on June 3, 2026.

SEC source: 0001178670-26-000048 · form4.xml · nonDerivative · entry 5

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,599

F1 · kind: The transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on November 12, 2025. The options exercised by the reporting person were due to expire on June 3, 2026.

F5 · price: The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $300.45 to $301.15. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

SEC source: 0001178670-26-000048 · form4.xml · nonDerivative · entry 4

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 2,094

F1 · kind: The transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on November 12, 2025. The options exercised by the reporting person were due to expire on June 3, 2026.

F4 · price: The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $299.36 to $300.19. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

SEC source: 0001178670-26-000048 · form4.xml · nonDerivative · entry 3

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 3,316

F1 · kind: The transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on November 12, 2025. The options exercised by the reporting person were due to expire on June 3, 2026.

F3 · price: The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $298.33 to $299.33. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

SEC source: 0001178670-26-000048 · form4.xml · nonDerivative · entry 2

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 4,491

F1 · kind: The transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on November 12, 2025. The options exercised by the reporting person were due to expire on June 3, 2026.

F2 · price: The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $297.31 to $297.99. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

SEC source: 0001178670-26-000048 · form4.xml · nonDerivative · entry 1

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 5,412

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on November 12, 2025. The options exercised by the reporting person were due to expire on June 3, 2026.

SEC source: 0001178670-26-000039 · form4.xml · derivative · entry 3

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,441

Underlying: Common Stock · 1,441 shares

Expires 2036-05-20

F3 · derivative.exercise_date: The stock option will vest in full upon the earlier of the first anniversary of the grant date and the date of any earlier retirement or resignation of the Reporting Person, provided such date of retirement or resignation occurs no more than 90 days prior to the first anniversary of the grant date.

SEC source: 0001178670-26-000039 · form4.xml · nonDerivative · entry 1

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,582

F1 · shares: These shares are represented by restricted stock units (RSUs) granted under the Second Amended and Restated 2018 Stock Incentive Plan. Each RSU represents a contingent right to receive one share of common stock. The RSUs will vest in full upon the earlier of the first anniversary of the grant date and the date of any earlier retirement or resignation of the Reporting Person, provided such date of retirement or resignation occurs no more than 90 days prior to the first anniversary of the grant date.

SEC source: 0001051578-26-000006 · wk-form4_1777407836.xml · derivative · entry 3

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 1,383 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each RSU represents a contingent right to receive one share of the Company's common stock.

F3 · derivative.exercise_date: The RSUs vested in full on April 24, 2026, subject to the Reporting Person's continuous service.

F3 · derivative.expiration_date: The RSUs vested in full on April 24, 2026, subject to the Reporting Person's continuous service.

SEC source: 0001051578-26-000006 · wk-form4_1777407836.xml · nonDerivative · entry 1

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,383

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The shares were issued pursuant to settlement of vested Restricted Stock Units ("RSUs"). Each RSU represents a contingent right to receive one share of the Company's common stock.

F1 · price: The shares were issued pursuant to settlement of vested Restricted Stock Units ("RSUs"). Each RSU represents a contingent right to receive one share of the Company's common stock.

SEC source: 0001051578-26-000004 · wk-form4_1771623346.xml · derivative · entry 2

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 3,729

Underlying: Common Stock · 3,729 shares

Expires not disclosed

F2 · derivative.exercise_price: Each Restricted Stock Unit ("RSU") represents a contingent right to receive one share of the Company's common stock.

F3 · derivative.exercise_date: The RSUs will vest in three equal annual installments on March 15th of each of 2027, 2028, and 2029, subject to the Reporting Person's continuous service.

F3 · derivative.expiration_date: The RSUs will vest in three equal annual installments on March 15th of each of 2027, 2028, and 2029, subject to the Reporting Person's continuous service.

SEC source: 0001051578-26-000004 · wk-form4_1771623346.xml · derivative · entry 1

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,893

Underlying: Common Stock · 5,893 shares

Expires 2036-02-17

F1 · derivative.exercise_date: The option shares will vest in three equal annual installments on February 18th of each of 2027, 2028, and 2029, subject to the Reporting Person's continuous service.

SEC source: 0001746473-25-000126 · wk-form4_1749516194.xml · derivative · entry 1

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 30,000

Underlying: Common Stock · 30,000 shares

Expires 2035-06-05

F1 · derivative.exercise_date: 25% of the shares subject to such option vest and become exercisable on October 1, 2025, January 1, 2026, and April 1, 2026, respectively, and the remaining 25% of the shares subject to such option vest and become exercisable on the earlier of (i) the one-year anniversary of the June 5, 2025 grant date or (ii) the next annual meeting of stockholders, subject to the Reporting Person's continued service to the Issuer as a Director through each such date or, if earlier, such annual meeting.

SEC source: 0001735276-25-000063 · edgardoc.xml · derivative · entry 3

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,558

Underlying: Common Stock · 1,558 shares

Expires 2035-05-08

F3 · derivative.exercise_date: The stock option vests in full upon the earlier of the first anniversary of the grant date and the date of any earlier retirement or resignation of the Reporting Person, provided such date of retirement or resignation occurs no more than 90 days prior to the first anniversary of the grant date.

SEC source: 0001735276-25-000063 · edgardoc.xml · nonDerivative · entry 1

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 911

F1 · shares: These shares are represented by restricted stock units (RSUs) granted under the Amended and Restated 2018 Stock Incentive Plan. Each RSU represents a contingent right to receive one share of common stock. The RSUs will vest in full upon the earlier of the first anniversary of the grant date and the date of any earlier retirement or resignation of the Reporting Person, provided such date of retirement or resignation occurs no more than 90 days prior to the first anniversary of the grant date.

SEC source: 0001735276-25-000040 · edgardoc.xml · derivative · entry 4

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 7,440 shares

Expires 2025-12-18

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on September 5, 2024. The options exercised and sold by the reporting person were due to expire on December 18, 2025.

F3 · derivative.exercise_date: This stock option was fully vested and exercisable as of December 18, 2016.

SEC source: 0001735276-25-000040 · edgardoc.xml · nonDerivative · entry 2

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 136

F1 · kind: The transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on September 5, 2024. The options exercised and sold by the reporting person were due to expire on December 18, 2025.

SEC source: 0001735276-25-000040 · edgardoc.xml · nonDerivative · entry 1

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 7,576

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on September 5, 2024. The options exercised and sold by the reporting person were due to expire on December 18, 2025.

SEC source: 0001735276-24-000070 · edgardoc.xml · derivative · entry 10

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 7,440

Underlying: Common Stock · 17,560 shares

Expires 2025-12-18

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on August 11, 2023.

F5 · derivative.exercise_date: This stock option was fully vested and exercisable as of December 18, 2018.

SEC source: 0001735276-24-000070 · edgardoc.xml · derivative · entry 9

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 3,780

Underlying: Common Stock · 7,470 shares

Expires 2027-06-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on August 11, 2023.

F4 · derivative.exercise_date: This stock option was fully vested and exercisable as of June 2, 2018.

SEC source: 0001735276-24-000070 · edgardoc.xml · derivative · entry 8

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 3,830

Underlying: Common Stock · 7,420 shares

Expires 2026-06-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on August 11, 2023.

F3 · derivative.exercise_date: This stock option was fully vested and exercisable as of June 3, 2017.

SEC source: 0001735276-24-000070 · edgardoc.xml · nonDerivative · entry 6

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 136

F1 · kind: The transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on August 11, 2023.

SEC source: 0001735276-24-000070 · edgardoc.xml · nonDerivative · entry 5

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 7,606

F1 · kind: The transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on August 11, 2023.

SEC source: 0001735276-24-000070 · edgardoc.xml · nonDerivative · entry 4

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 15,026

F1 · kind: The transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on August 11, 2023.

SEC source: 0001735276-24-000070 · edgardoc.xml · nonDerivative · entry 3

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 32,586

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on August 11, 2023.

SEC source: 0001735276-24-000070 · edgardoc.xml · nonDerivative · entry 2

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 25,116

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on August 11, 2023.

SEC source: 0001735276-24-000070 · edgardoc.xml · nonDerivative · entry 1

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 17,696

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on August 11, 2023.

SEC source: 0001746473-24-000105 · wk-form4_1718669756.xml · derivative · entry 1

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 26,764

Underlying: Common Stock · 26,764 shares

Expires 2034-06-13

F1 · derivative.exercise_date: 25% of the shares subject to such option vest and become exercisable on the first day of each calendar quarter for three calendar quarters following the June 13th, 2024 grant date and the remaining 25% of the shares subject to such option vest and become exercisable on the earlier of (i) the one-year anniversary of the June 13, 2024 grant date or (ii) the next annual meeting of stockholders, subject to the Reporting Person's continued service to the Issuer as a Director through each such date or, if earlier, such annual meeting.

SEC source: 0001048477-24-000110 · wk-form4_1716500181.xml · nonDerivative · entry 1

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 49,750

F1 · price: Restricted stock units granted on May 21, 2024. Price not applicable.

SEC source: 0001735276-24-000055 · edgardoc.xml · derivative · entry 1

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,228

Underlying: Common Stock · 5,228 shares

Expires 2034-05-16

F1 · derivative.exercise_date: This award vests in full upon the earlier of the first anniversary of the grant date and the date of any earlier retirement or resignation of the Reporting Person, provided such date of retirement or resignation occurs no more than 90 days prior to the first anniversary of the grant date.

SEC source: 0001209191-23-035538 · doc4.xml · derivative · entry 1

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,000

Underlying: Common Stock · 14,000 shares

Expires 2033-06-07

F1 · derivative.exercise_date: 25% of the shares subject to such option vest and become exercisable on the first day of each calendar quarter for three calendar quarters following the June 7th, 2023 grant date and the remaining 25% of the shares subject to such option vest and become exercisable on the earlier of (i) the one-year anniversary of the June 7th, 2023 grant date, or (ii) the 2024 Annual Meeting of Stockholders, subject to the Reporting Person's continued service to the Issuer as a Director through each such date or, if earlier, such annual meeting.

SEC source: 0001209191-23-031977 · doc4.xml · nonDerivative · entry 1

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 45,030

F1 · price: Restricted stock units granted on May 23, 2023. Price not applicable.

SEC source: 0001735276-23-000068 · edgardoc.xml · derivative · entry 1

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 3,454

Underlying: Common Stock · 3,454 shares

Expires 2033-05-18

F1 · derivative.exercise_date: This award vests in full upon the earlier of the first anniversary of the grant date and the date of any earlier retirement or resignation of the Reporting Person, provided such date of retirement or resignation occurs no more than 90 days prior to the first anniversary of the grant date.

SEC source: 0001735276-23-000018 · edgardoc.xml · derivative · entry 3

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 136 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of ALNY common stock.

F3 · derivative.exercise_date: This award vested on February 23, 2023, the first anniversary of the grant date.

F3 · derivative.expiration_date: This award vested on February 23, 2023, the first anniversary of the grant date.

SEC source: 0001735276-23-000018 · edgardoc.xml · nonDerivative · entry 1

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 136

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001567619-22-013200 · doc1.xml · derivative · entry 1

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 15,000 shares

Expires 2032-06-15

F1 · derivative.exercise_date: 25% of the shares subject to such option vest and become exercisable on the first day of each calendar quarter for three calendar quarters beginning October 1st and the remaining 25% of the shares subject to such option vest and become exercisable on the earlier of (i) the one-year anniversary of June 16, 2022 or (ii) the next annual meeting of the stockholders, subject to the Reporting Person's continued service to the Issuer as a director through each such date or, if earlier, such annual meeting.

SEC source: 0001567619-22-011800 · doc1.xml · nonDerivative · entry 1

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,840

F1 · price: Restricted stock units granted on May 24, 2022. Price not applicable.

SEC source: 0001735276-22-000055 · edgardoc.xml · derivative · entry 1

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,153

Underlying: Common Stock · 5,153 shares

Expires 2032-05-17

F1 · derivative.exercise_date: This award vests in full upon the earlier of the first anniversary of the grant date and the date of any earlier retirement or resignation of the Reporting Person, provided such date of retirement or resignation occurs no more than 90 days prior to the first anniversary of the grant date.

SEC source: 0001735276-22-000028 · edgardoc.xml · derivative · entry 1

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 136

Underlying: Common Stock · 136 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of ALNY common stock.

F2 · derivative.exercise_date: This award vests in full upon the earlier of the first anniversary of the grant date and the date of any earlier retirement or resignation of the Reporting Person, provided such date of retirement or resignation occurs no more than 90 days prior to the first anniversary of the grant date.

F2 · derivative.expiration_date: This award vests in full upon the earlier of the first anniversary of the grant date and the date of any earlier retirement or resignation of the Reporting Person, provided such date of retirement or resignation occurs no more than 90 days prior to the first anniversary of the grant date.

SEC source: 0001735276-21-000073 · edgardoc.xml · derivative · entry 1

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,032

Underlying: Common Stock · 4,032 shares

Expires 2031-07-14

F1 · derivative.exercise_date: This award vests in full upon the earlier of the first anniversary of the grant date and the date of any earlier retirement or resignation of the Reporting Person, provided such date of retirement or resignation occurs no more than 90 days prior to the first anniversary of the grant date.

SEC source: 0001209191-21-044180 · doc4.xml · derivative · entry 1

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,286

Underlying: Common Stock · 13,286 shares

Expires 2021-06-28

F1 · derivative.exercise_date: 25% of the shares subject to such option vest and become exercisable on the first day of each calendar quarter following June 29, 2021 for three calendar quarters and the remaining 25% of the shares subject to such option vest and become exercisable on the earlier of (i) the one-year anniversary of June 29, 2021 or (ii) the next annual meeting of the stockholders, subject to the Reporting Person's continued service to the Issuer as a director through each such date or, if earlier, such annual meeting.

SEC source: 0001209191-21-044628 · doc4a.xml · derivative · entry 1

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,286

Underlying: Common Stock · 13,286 shares

Expires 2031-06-28

F1 · derivative.exercise_date: 25% of the shares subject to such option vest and become exercisable on the first day of each calendar quarter following June 29, 2021 for three calendar quarters and the remaining 25% of the shares subject to such option vest and become exercisable on the earlier of (i) the one-year anniversary of June 29, 2021 or (ii) the next annual meeting of the stockholders, subject to the Reporting Person's continued service to the Issuer as a director through each such date or, if earlier, such annual meeting.

SEC source: 0001567619-21-011320 · doc1.xml · nonDerivative · entry 1

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 35,860

F1 · price: Restricted stock units granted on May 25, 2021. Price not applicable.

SEC source: 0000899243-21-001875 · doc4.xml · derivative · entry 1

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,573

Underlying: Common Stock · 26,573 shares

Expires 2031-01-11

F1 · derivative.exercise_date: 1/36th of the shares subject to such option vest and become exercisable in substantially equal installments on each monthly anniversary of January 12, 2021, subject to the Reporting Person's continuous service to the Issuer on each such date.