Cossman Jeffrey

SEC source: 0001104659-26-084266 · tm2620684-2_4seq1.xml · nonDerivative · entry 1

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,549

F1 · shares: 416 shares of common stock were granted upon the close of business on July 15, 2026, as a consideration in lieu of cash payment of compensation for service as a member of the Board of Directors for Q2-26.

SEC source: 0001104659-26-044951 · tm2612069-2_4seq1.xml · nonDerivative · entry 1

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,133

F1 · shares: 365 shares of common stock were granted upon the close of business on April 15, 2026, as a consideration in lieu of cash payment of compensation for service as a member of the Board of Directors for Q1-26.

SEC source: 0001104659-26-005045 · tm263642-3_4seq1.xml · nonDerivative · entry 1

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 15,777

F1 · shares: 437 shares of common stock were granted upon the close of business on January 15, 2026, as a consideration in lieu of cash payment of compensation for service as a member of the Board of Directors for Q4-25.

F1 · price: 437 shares of common stock were granted upon the close of business on January 15, 2026, as a consideration in lieu of cash payment of compensation for service as a member of the Board of Directors for Q4-25.

SEC source: 0001104659-26-001342 · tm261953-3_4seq1.xml · derivative · entry 1

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,500

Underlying: Common Stock · 1,500 shares

Expires 2036-01-02

F2 · price: The stock option was granted pursuant to the Issuer's Equity Incentive Plan in consideration for the Reporting Person's service as a director of the Issuer and has an exercise price of $23.82 per share.

F1 · derivative.exercise_date: The options shall vest in twelve equal monthly installments beginning on the one-month anniversary of the date of the issuance.

SEC source: 0001104659-25-100108 · tm2528907-3_4seq1.xml · nonDerivative · entry 1

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 15,247

F1 · shares: 597 shares of common stock were granted upon the close of business on October 15, 2025, as a consideration in lieu of cash payment of compensation for service as a member of the Board of Directors for Q3-25.

SEC source: 0001104659-26-005072 · tm263642-8_4aseq1.xml · nonDerivative · entry 1

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 15,340

F1 · price: This Form 4/A is being filed to correct the reporting person's aggregate beneficial ownership, which was understated by 93 shares in the original Form 4 filed on October 15, 2025 due to an administrative reporting error. No additional transactions occurred other than those previously reported.

F1 · balance_after: This Form 4/A is being filed to correct the reporting person's aggregate beneficial ownership, which was understated by 93 shares in the original Form 4 filed on October 15, 2025 due to an administrative reporting error. No additional transactions occurred other than those previously reported.

SEC source: 0001104659-25-069085 · tm2521261-1_4aseq1.xml · nonDerivative · entry 1

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,743

F1 · shares: This Form 4/A amends the Form 4 filed on July 18, 2025, to correct the number of shares and grant date previously reported. Mr. Cossman was granted 710 shares of common stock as of the close of business on July 16, 2025, as equity compensation in lieu of a cash payment for his service on the Board of Directors for Q2-2025.

SEC source: 0001104659-25-004158 · tm253548d3_4seq1.xml · nonDerivative · entry 1

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,033

F1 · shares: 1,721 shares of common stock were granted upon the close of business on January 15, 2025, as a consideration in lieu of cash payment of compensation for service as a member of the Board of Directors for Q4-24.

SEC source: 0001104659-25-069053 · tm2521234-1_4seq1.xml · nonDerivative · entry 1

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,033

F1 · shares: 1,721 shares of common stock were granted upon the close of business on January 15, 2025, as a consideration in lieu of cash payment of compensation for service as a member of the Board of Directors for Q4-24.

SEC source: 0001104659-25-004167 · tm253548-7_4seq1.xml · derivative · entry 1

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,000

Underlying: Common Stock · 1,000 shares

Expires 2035-01-14

F2 · price: Issued pursuant to the Issuer's Equity Incentive Plan in consideration for the Reporting Person's service as a director of the Issuer.

F1 · derivative.exercise_date: The options shall vest in twelve equal monthly installments beginning on the one-month anniversary of the date of the issuance.

SEC source: 0001104659-24-109552 · tm2426435-3_4seq1.xml · nonDerivative · entry 1

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 12,312

F1 · price: 1,586 shares of common stock were granted upon the close of business on October 15, 2024, as a consideration in lieu of cash payment of compensation for service as a member of the Board of Directors for Q3-24.

SEC source: 0001104659-24-097787 · tm2423539-3_4seq1.xml · derivative · entry 20

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,000

Underlying: Common Stock · 2,000 shares

Expires 2032-01-11

F3 · derivative.exercise_price: The exercise price of the option is $6.56 per share, representing the fair market value per share of the Issuer's Common Stock on the Effective Date; provided that the repriced option will revert to its original exercise price if, prior to the first anniversary of the Effective Date, (a) the Reporting Person's service with the Issuer is terminated by the Issuer with cause or by the Reporting Person or (b) the option is exercised

F1 · kind: On August 30, 2024, the Issuer's Board of Directors approved an option repricing (the "Repricing"), effective as of August 31, 2024 (the "Effective Date"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable.

F1 · price: On August 30, 2024, the Issuer's Board of Directors approved an option repricing (the "Repricing"), effective as of August 31, 2024 (the "Effective Date"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable.

F2 · derivative.exercise_date: This stock option award was issued pursuant to the Company's Amended and Restated 2017 Stock Option and Incentive Plan, as amended, (the "2017 Plan") and becomes exercisable in accordance with the vesting schedule specified in the award agreement and as previously reported on applicable Form-4, subject to the Reporting Person's continued service with the Issuer as of the applicable vesting date.

SEC source: 0001104659-24-097787 · tm2423539-3_4seq1.xml · derivative · entry 19

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 2,000 shares

Expires 2032-01-11

F1 · kind: On August 30, 2024, the Issuer's Board of Directors approved an option repricing (the "Repricing"), effective as of August 31, 2024 (the "Effective Date"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable.

F1 · price: On August 30, 2024, the Issuer's Board of Directors approved an option repricing (the "Repricing"), effective as of August 31, 2024 (the "Effective Date"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable.

F2 · derivative.exercise_date: This stock option award was issued pursuant to the Company's Amended and Restated 2017 Stock Option and Incentive Plan, as amended, (the "2017 Plan") and becomes exercisable in accordance with the vesting schedule specified in the award agreement and as previously reported on applicable Form-4, subject to the Reporting Person's continued service with the Issuer as of the applicable vesting date.

SEC source: 0001104659-24-097787 · tm2423539-3_4seq1.xml · derivative · entry 18

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,250

Underlying: Common Stock · 1,250 shares

Expires 2031-03-08

F3 · derivative.exercise_price: The exercise price of the option is $6.56 per share, representing the fair market value per share of the Issuer's Common Stock on the Effective Date; provided that the repriced option will revert to its original exercise price if, prior to the first anniversary of the Effective Date, (a) the Reporting Person's service with the Issuer is terminated by the Issuer with cause or by the Reporting Person or (b) the option is exercised

F1 · kind: On August 30, 2024, the Issuer's Board of Directors approved an option repricing (the "Repricing"), effective as of August 31, 2024 (the "Effective Date"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable.

F1 · price: On August 30, 2024, the Issuer's Board of Directors approved an option repricing (the "Repricing"), effective as of August 31, 2024 (the "Effective Date"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable.

F2 · derivative.exercise_date: This stock option award was issued pursuant to the Company's Amended and Restated 2017 Stock Option and Incentive Plan, as amended, (the "2017 Plan") and becomes exercisable in accordance with the vesting schedule specified in the award agreement and as previously reported on applicable Form-4, subject to the Reporting Person's continued service with the Issuer as of the applicable vesting date.

SEC source: 0001104659-24-097787 · tm2423539-3_4seq1.xml · derivative · entry 17

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 1,250 shares

Expires 2031-03-08

F1 · kind: On August 30, 2024, the Issuer's Board of Directors approved an option repricing (the "Repricing"), effective as of August 31, 2024 (the "Effective Date"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable.

F1 · price: On August 30, 2024, the Issuer's Board of Directors approved an option repricing (the "Repricing"), effective as of August 31, 2024 (the "Effective Date"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable.

F2 · derivative.exercise_date: This stock option award was issued pursuant to the Company's Amended and Restated 2017 Stock Option and Incentive Plan, as amended, (the "2017 Plan") and becomes exercisable in accordance with the vesting schedule specified in the award agreement and as previously reported on applicable Form-4, subject to the Reporting Person's continued service with the Issuer as of the applicable vesting date.

SEC source: 0001104659-24-097787 · tm2423539-3_4seq1.xml · derivative · entry 16

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,250

Underlying: Common Stock · 1,250 shares

Expires 2031-01-04

F3 · derivative.exercise_price: The exercise price of the option is $6.56 per share, representing the fair market value per share of the Issuer's Common Stock on the Effective Date; provided that the repriced option will revert to its original exercise price if, prior to the first anniversary of the Effective Date, (a) the Reporting Person's service with the Issuer is terminated by the Issuer with cause or by the Reporting Person or (b) the option is exercised

F1 · kind: On August 30, 2024, the Issuer's Board of Directors approved an option repricing (the "Repricing"), effective as of August 31, 2024 (the "Effective Date"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable.

F1 · price: On August 30, 2024, the Issuer's Board of Directors approved an option repricing (the "Repricing"), effective as of August 31, 2024 (the "Effective Date"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable.

F2 · derivative.exercise_date: This stock option award was issued pursuant to the Company's Amended and Restated 2017 Stock Option and Incentive Plan, as amended, (the "2017 Plan") and becomes exercisable in accordance with the vesting schedule specified in the award agreement and as previously reported on applicable Form-4, subject to the Reporting Person's continued service with the Issuer as of the applicable vesting date.

SEC source: 0001104659-24-097787 · tm2423539-3_4seq1.xml · derivative · entry 15

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 1,250 shares

Expires 2031-01-04

F1 · kind: On August 30, 2024, the Issuer's Board of Directors approved an option repricing (the "Repricing"), effective as of August 31, 2024 (the "Effective Date"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable.

F1 · price: On August 30, 2024, the Issuer's Board of Directors approved an option repricing (the "Repricing"), effective as of August 31, 2024 (the "Effective Date"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable.

F2 · derivative.exercise_date: This stock option award was issued pursuant to the Company's Amended and Restated 2017 Stock Option and Incentive Plan, as amended, (the "2017 Plan") and becomes exercisable in accordance with the vesting schedule specified in the award agreement and as previously reported on applicable Form-4, subject to the Reporting Person's continued service with the Issuer as of the applicable vesting date.

SEC source: 0001104659-24-097787 · tm2423539-3_4seq1.xml · derivative · entry 14

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,087

Underlying: Common Stock · 1,087 shares

Expires 2030-07-02

F3 · derivative.exercise_price: The exercise price of the option is $6.56 per share, representing the fair market value per share of the Issuer's Common Stock on the Effective Date; provided that the repriced option will revert to its original exercise price if, prior to the first anniversary of the Effective Date, (a) the Reporting Person's service with the Issuer is terminated by the Issuer with cause or by the Reporting Person or (b) the option is exercised

F1 · kind: On August 30, 2024, the Issuer's Board of Directors approved an option repricing (the "Repricing"), effective as of August 31, 2024 (the "Effective Date"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable.

F1 · price: On August 30, 2024, the Issuer's Board of Directors approved an option repricing (the "Repricing"), effective as of August 31, 2024 (the "Effective Date"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable.

F2 · derivative.exercise_date: This stock option award was issued pursuant to the Company's Amended and Restated 2017 Stock Option and Incentive Plan, as amended, (the "2017 Plan") and becomes exercisable in accordance with the vesting schedule specified in the award agreement and as previously reported on applicable Form-4, subject to the Reporting Person's continued service with the Issuer as of the applicable vesting date.

SEC source: 0001104659-24-097787 · tm2423539-3_4seq1.xml · derivative · entry 13

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 1,087 shares

Expires 2030-07-02

F1 · kind: On August 30, 2024, the Issuer's Board of Directors approved an option repricing (the "Repricing"), effective as of August 31, 2024 (the "Effective Date"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable.

F1 · price: On August 30, 2024, the Issuer's Board of Directors approved an option repricing (the "Repricing"), effective as of August 31, 2024 (the "Effective Date"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable.

F2 · derivative.exercise_date: This stock option award was issued pursuant to the Company's Amended and Restated 2017 Stock Option and Incentive Plan, as amended, (the "2017 Plan") and becomes exercisable in accordance with the vesting schedule specified in the award agreement and as previously reported on applicable Form-4, subject to the Reporting Person's continued service with the Issuer as of the applicable vesting date.

SEC source: 0001104659-24-097787 · tm2423539-3_4seq1.xml · derivative · entry 12

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 200

Underlying: Common Stock · 200 shares

Expires 2030-07-02

F3 · derivative.exercise_price: The exercise price of the option is $6.56 per share, representing the fair market value per share of the Issuer's Common Stock on the Effective Date; provided that the repriced option will revert to its original exercise price if, prior to the first anniversary of the Effective Date, (a) the Reporting Person's service with the Issuer is terminated by the Issuer with cause or by the Reporting Person or (b) the option is exercised

F1 · kind: On August 30, 2024, the Issuer's Board of Directors approved an option repricing (the "Repricing"), effective as of August 31, 2024 (the "Effective Date"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable.

F1 · price: On August 30, 2024, the Issuer's Board of Directors approved an option repricing (the "Repricing"), effective as of August 31, 2024 (the "Effective Date"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable.

F2 · derivative.exercise_date: This stock option award was issued pursuant to the Company's Amended and Restated 2017 Stock Option and Incentive Plan, as amended, (the "2017 Plan") and becomes exercisable in accordance with the vesting schedule specified in the award agreement and as previously reported on applicable Form-4, subject to the Reporting Person's continued service with the Issuer as of the applicable vesting date.

SEC source: 0001104659-24-097787 · tm2423539-3_4seq1.xml · derivative · entry 11

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 200 shares

Expires 2030-07-02

F1 · kind: On August 30, 2024, the Issuer's Board of Directors approved an option repricing (the "Repricing"), effective as of August 31, 2024 (the "Effective Date"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable.

F1 · price: On August 30, 2024, the Issuer's Board of Directors approved an option repricing (the "Repricing"), effective as of August 31, 2024 (the "Effective Date"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable.

F2 · derivative.exercise_date: This stock option award was issued pursuant to the Company's Amended and Restated 2017 Stock Option and Incentive Plan, as amended, (the "2017 Plan") and becomes exercisable in accordance with the vesting schedule specified in the award agreement and as previously reported on applicable Form-4, subject to the Reporting Person's continued service with the Issuer as of the applicable vesting date.

SEC source: 0001104659-24-097787 · tm2423539-3_4seq1.xml · derivative · entry 10

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 375

Underlying: Common Stock · 375 shares

Expires 2030-01-16

F3 · derivative.exercise_price: The exercise price of the option is $6.56 per share, representing the fair market value per share of the Issuer's Common Stock on the Effective Date; provided that the repriced option will revert to its original exercise price if, prior to the first anniversary of the Effective Date, (a) the Reporting Person's service with the Issuer is terminated by the Issuer with cause or by the Reporting Person or (b) the option is exercised

F1 · kind: On August 30, 2024, the Issuer's Board of Directors approved an option repricing (the "Repricing"), effective as of August 31, 2024 (the "Effective Date"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable.

F1 · price: On August 30, 2024, the Issuer's Board of Directors approved an option repricing (the "Repricing"), effective as of August 31, 2024 (the "Effective Date"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable.

F2 · derivative.exercise_date: This stock option award was issued pursuant to the Company's Amended and Restated 2017 Stock Option and Incentive Plan, as amended, (the "2017 Plan") and becomes exercisable in accordance with the vesting schedule specified in the award agreement and as previously reported on applicable Form-4, subject to the Reporting Person's continued service with the Issuer as of the applicable vesting date.

SEC source: 0001104659-24-097787 · tm2423539-3_4seq1.xml · derivative · entry 9

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 375 shares

Expires 2030-01-16

F1 · kind: On August 30, 2024, the Issuer's Board of Directors approved an option repricing (the "Repricing"), effective as of August 31, 2024 (the "Effective Date"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable.

F1 · price: On August 30, 2024, the Issuer's Board of Directors approved an option repricing (the "Repricing"), effective as of August 31, 2024 (the "Effective Date"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable.

F2 · derivative.exercise_date: This stock option award was issued pursuant to the Company's Amended and Restated 2017 Stock Option and Incentive Plan, as amended, (the "2017 Plan") and becomes exercisable in accordance with the vesting schedule specified in the award agreement and as previously reported on applicable Form-4, subject to the Reporting Person's continued service with the Issuer as of the applicable vesting date.

SEC source: 0001104659-24-097787 · tm2423539-3_4seq1.xml · derivative · entry 8

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 250

Underlying: Common Stock · 250 shares

Expires 2029-03-18

F3 · derivative.exercise_price: The exercise price of the option is $6.56 per share, representing the fair market value per share of the Issuer's Common Stock on the Effective Date; provided that the repriced option will revert to its original exercise price if, prior to the first anniversary of the Effective Date, (a) the Reporting Person's service with the Issuer is terminated by the Issuer with cause or by the Reporting Person or (b) the option is exercised

F1 · kind: On August 30, 2024, the Issuer's Board of Directors approved an option repricing (the "Repricing"), effective as of August 31, 2024 (the "Effective Date"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable.

F1 · price: On August 30, 2024, the Issuer's Board of Directors approved an option repricing (the "Repricing"), effective as of August 31, 2024 (the "Effective Date"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable.

F2 · derivative.exercise_date: This stock option award was issued pursuant to the Company's Amended and Restated 2017 Stock Option and Incentive Plan, as amended, (the "2017 Plan") and becomes exercisable in accordance with the vesting schedule specified in the award agreement and as previously reported on applicable Form-4, subject to the Reporting Person's continued service with the Issuer as of the applicable vesting date.

SEC source: 0001104659-24-097787 · tm2423539-3_4seq1.xml · derivative · entry 7

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 250 shares

Expires 2029-03-18

F1 · kind: On August 30, 2024, the Issuer's Board of Directors approved an option repricing (the "Repricing"), effective as of August 31, 2024 (the "Effective Date"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable.

F1 · price: On August 30, 2024, the Issuer's Board of Directors approved an option repricing (the "Repricing"), effective as of August 31, 2024 (the "Effective Date"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable.

F2 · derivative.exercise_date: This stock option award was issued pursuant to the Company's Amended and Restated 2017 Stock Option and Incentive Plan, as amended, (the "2017 Plan") and becomes exercisable in accordance with the vesting schedule specified in the award agreement and as previously reported on applicable Form-4, subject to the Reporting Person's continued service with the Issuer as of the applicable vesting date.

SEC source: 0001104659-24-097787 · tm2423539-3_4seq1.xml · derivative · entry 6

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 258

Underlying: Common Stock · 258 shares

Expires 2028-02-16

F3 · derivative.exercise_price: The exercise price of the option is $6.56 per share, representing the fair market value per share of the Issuer's Common Stock on the Effective Date; provided that the repriced option will revert to its original exercise price if, prior to the first anniversary of the Effective Date, (a) the Reporting Person's service with the Issuer is terminated by the Issuer with cause or by the Reporting Person or (b) the option is exercised

F1 · kind: On August 30, 2024, the Issuer's Board of Directors approved an option repricing (the "Repricing"), effective as of August 31, 2024 (the "Effective Date"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable.

F1 · price: On August 30, 2024, the Issuer's Board of Directors approved an option repricing (the "Repricing"), effective as of August 31, 2024 (the "Effective Date"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable.

F2 · derivative.exercise_date: This stock option award was issued pursuant to the Company's Amended and Restated 2017 Stock Option and Incentive Plan, as amended, (the "2017 Plan") and becomes exercisable in accordance with the vesting schedule specified in the award agreement and as previously reported on applicable Form-4, subject to the Reporting Person's continued service with the Issuer as of the applicable vesting date.

SEC source: 0001104659-24-097787 · tm2423539-3_4seq1.xml · derivative · entry 5

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 258 shares

Expires 2028-02-16

F1 · kind: On August 30, 2024, the Issuer's Board of Directors approved an option repricing (the "Repricing"), effective as of August 31, 2024 (the "Effective Date"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable.

F1 · price: On August 30, 2024, the Issuer's Board of Directors approved an option repricing (the "Repricing"), effective as of August 31, 2024 (the "Effective Date"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable.

F2 · derivative.exercise_date: This stock option award was issued pursuant to the Company's Amended and Restated 2017 Stock Option and Incentive Plan, as amended, (the "2017 Plan") and becomes exercisable in accordance with the vesting schedule specified in the award agreement and as previously reported on applicable Form-4, subject to the Reporting Person's continued service with the Issuer as of the applicable vesting date.

SEC source: 0001104659-24-097787 · tm2423539-3_4seq1.xml · derivative · entry 4

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 103

Underlying: Common Stock · 103 shares

Expires 2028-02-16

F3 · derivative.exercise_price: The exercise price of the option is $6.56 per share, representing the fair market value per share of the Issuer's Common Stock on the Effective Date; provided that the repriced option will revert to its original exercise price if, prior to the first anniversary of the Effective Date, (a) the Reporting Person's service with the Issuer is terminated by the Issuer with cause or by the Reporting Person or (b) the option is exercised

F1 · kind: On August 30, 2024, the Issuer's Board of Directors approved an option repricing (the "Repricing"), effective as of August 31, 2024 (the "Effective Date"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable.

F1 · price: On August 30, 2024, the Issuer's Board of Directors approved an option repricing (the "Repricing"), effective as of August 31, 2024 (the "Effective Date"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable.

F2 · derivative.exercise_date: This stock option award was issued pursuant to the Company's Amended and Restated 2017 Stock Option and Incentive Plan, as amended, (the "2017 Plan") and becomes exercisable in accordance with the vesting schedule specified in the award agreement and as previously reported on applicable Form-4, subject to the Reporting Person's continued service with the Issuer as of the applicable vesting date.

SEC source: 0001104659-24-097787 · tm2423539-3_4seq1.xml · derivative · entry 3

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 103 shares

Expires 2028-02-16

F1 · kind: On August 30, 2024, the Issuer's Board of Directors approved an option repricing (the "Repricing"), effective as of August 31, 2024 (the "Effective Date"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable.

F1 · price: On August 30, 2024, the Issuer's Board of Directors approved an option repricing (the "Repricing"), effective as of August 31, 2024 (the "Effective Date"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable.

F2 · derivative.exercise_date: This stock option award was issued pursuant to the Company's Amended and Restated 2017 Stock Option and Incentive Plan, as amended, (the "2017 Plan") and becomes exercisable in accordance with the vesting schedule specified in the award agreement and as previously reported on applicable Form-4, subject to the Reporting Person's continued service with the Issuer as of the applicable vesting date.

SEC source: 0001104659-24-097787 · tm2423539-3_4seq1.xml · derivative · entry 2

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 23

Underlying: Common Stock · 23 shares

Expires 2027-09-26

F3 · derivative.exercise_price: The exercise price of the option is $6.56 per share, representing the fair market value per share of the Issuer's Common Stock on the Effective Date; provided that the repriced option will revert to its original exercise price if, prior to the first anniversary of the Effective Date, (a) the Reporting Person's service with the Issuer is terminated by the Issuer with cause or by the Reporting Person or (b) the option is exercised

F1 · kind: On August 30, 2024, the Issuer's Board of Directors approved an option repricing (the "Repricing"), effective as of August 31, 2024 (the "Effective Date"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable.

F1 · price: On August 30, 2024, the Issuer's Board of Directors approved an option repricing (the "Repricing"), effective as of August 31, 2024 (the "Effective Date"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable.

F2 · derivative.exercise_date: This stock option award was issued pursuant to the Company's Amended and Restated 2017 Stock Option and Incentive Plan, as amended, (the "2017 Plan") and becomes exercisable in accordance with the vesting schedule specified in the award agreement and as previously reported on applicable Form-4, subject to the Reporting Person's continued service with the Issuer as of the applicable vesting date.

SEC source: 0001104659-24-097787 · tm2423539-3_4seq1.xml · derivative · entry 1

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 23 shares

Expires 2027-09-26

F1 · kind: On August 30, 2024, the Issuer's Board of Directors approved an option repricing (the "Repricing"), effective as of August 31, 2024 (the "Effective Date"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable.

F1 · price: On August 30, 2024, the Issuer's Board of Directors approved an option repricing (the "Repricing"), effective as of August 31, 2024 (the "Effective Date"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable.

F2 · derivative.exercise_date: This stock option award was issued pursuant to the Company's Amended and Restated 2017 Stock Option and Incentive Plan, as amended, (the "2017 Plan") and becomes exercisable in accordance with the vesting schedule specified in the award agreement and as previously reported on applicable Form-4, subject to the Reporting Person's continued service with the Issuer as of the applicable vesting date.

SEC source: 0001104659-24-080217 · tm2419567-3_4seq1.xml · nonDerivative · entry 1

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10.726

F1 · shares: 2,157 shares of common stock were granted upon the close of business on July 15, 2024, as a consideration in lieu of cash payment of compensation for service as a member of the Board of Directors for Q2-24.

SEC source: 0001104659-24-074790 · tm2418227-2_4seq1.xml · derivative · entry 1

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,000

Underlying: Common Stock · 1,000 shares

Expires 2034-06-21

F2 · price: Issued pursuant to the Issuer's Equity Incentive Plan in consideration for the Reporting Person's service as a director of the Issuer

F1 · derivative.exercise_date: The options shall vest in twelve equal monthly installments beginning on the one-month anniversary of the date of the issuance

SEC source: 0001104659-24-048328 · tm2412083-5_4seq1.xml · nonDerivative · entry 1

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,461

F1 · price: 8,143 shares of common stock were granted upon the close of business on April 15, 2024, as a consideration in lieu of cash payment of deferred compensation for service as a member of the Board of Directors for Q1-23 to Q4-23 and Q1-24. The price reported in Column 4 is a weighted average price ranging from $5.35 to $6.74. The reporting person undertakes to provide, upon request, full information regarding the number of shares calculated at each separate price within the range set forth in this footnote.

SEC source: 0001104659-23-100812 · tm2326171-3_4seq1.xml · nonDerivative · entry 1

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,363

F1 · price: The 6,363 restricted shares of common stock were granted upon the close of business on September 12, 2023 and vested immediately upon issuance. The restricted shares were issued as consideration in lieu of cash payment of deferred compensation for service as a member of the Board of Directors.

SEC source: 0001104659-23-002764 · tm233036-4_4seq1.xml · derivative · entry 1

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,000

Underlying: Common Stock · 30,000 shares

Expires 2033-01-06

F2 · price: Issued pursuant to the Issuer's Equity Incentive Plan in consideration for the Reporting Person's service as a director of the Issuer

F1 · derivative.exercise_date: The options shall vest in twelve equal monthly installments beginning on the one-month anniversary of the date of the issuance

SEC source: 0001104659-22-004063 · tm222906-5_4seq1.xml · derivative · entry 1

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,000

Underlying: Common Stock · 40,000 shares

Expires 2032-01-11

F2 · price: Issued pursuant to the Issuer's Equity Incentive Plan in consideration for the Reporting Person's service as a director of the Issuer

F1 · derivative.exercise_date: The options shall vest in twelve equal monthly installments beginning on the one month anniversary of the date of the issuance

SEC source: 0001104659-21-100858 · tm2124311-2_4seq1.xml · derivative · entry 1

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,000

Underlying: Common Stock · 25,000 shares

Expires 2031-08-03

F2 · price: Issued pursuant to the Issuer's Equity Incentive Plan in consideration for the Reporting Person's service as a director of the Issuer

F1 · derivative.exercise_date: The options shall vest in twelve equal monthly installments beginning on the one month anniversary of the date of the issuance

SEC source: 0001104659-21-000958 · tm211613-3_4seq1.xml · derivative · entry 1

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,000

Underlying: Common Stock · 25,000 shares

Expires 2031-01-04

F2 · price: Issued pursuant to the Issuer's Equity Incentive Plan in consideration for the Reporting Person's service as a director of the Issuer

F1 · derivative.exercise_date: The options shall vest in twelve equal monthly installments beginning on the one month anniversary of the date of the issuance

SEC source: 0001104659-20-081344 · tm2024163d9_4.xml · derivative · entry 1

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,000

Underlying: Common Stock · 4,000 shares

Expires 2030-07-02

F2 · price: Issued pursuant to the Company Equity Incentive Plan in consideration for the Reporting Person's service as a director of the Issuer

F1 · derivative.exercise_date: The options shall vest in twelve equal monthly installments beginning on the one month anniversary of the date of the issuance

SEC source: 0001104659-20-081340 · tm2024163d1_4.xml · derivative · entry 1

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,750

Underlying: Common Stock · 21,750 shares

Expires 2030-07-02

F2 · price: Issued pursuant to the Company Equity Incentive Plan in consideration for the Reporting Person's service and assistance to the Company in connection with matters related to the FDA.

F1 · derivative.exercise_date: The options shall vest on the date of the issuance

SEC source: 0001104659-20-005507 · tm205425-7_4.xml · derivative · entry 1

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,500

Underlying: Common Stock · 7,500 shares

Expires 2030-01-16

F2 · price: Issued pursuant to the Company Equity Incentive Plan in consideration for the Reporting Person's service as a director of the Issuer

F1 · derivative.exercise_date: The options shall vest in twelve equal monthly installments beginning on the one month anniversary of the date of the issuance

SEC source: 0001144204-19-015166 · tv516773_4.xml · derivative · entry 1

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 75,000

Underlying: Common Stock · 75,000 shares

Expires 2029-03-18

F2 · price: Issued pursuant to the Company Equity Incentive Plan in consideration for the Reporting Person's service as a director of the Issuer

F1 · derivative.exercise_date: The options shall vest in twelve equal monthly installments beginning on the one month anniversary of the date of the issuance

SEC source: 0000899243-18-004798 · doc4.xml · derivative · entry 2

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 77,563

Underlying: Common Stock · 77,563 shares

Expires 2028-02-16

F2 · derivative.exercise_date: This option shall vest as follows: shall vest in 36 equal monthly installments.

SEC source: 0000899243-18-004798 · doc4.xml · derivative · entry 1

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,025

Underlying: Common Stock · 31,025 shares

Expires 2028-02-16

F1 · derivative.exercise_date: This option shall vest as follows: shall vest in 12 equal monthly installments.

SEC source: 0000899243-17-022790 · doc4.xml · derivative · entry 1

Cossman Jeffrey · CIK 0001710127 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,000

Underlying: Common Stock · 7,000 shares

Expires 2027-09-26

F1 · derivative.exercise_date: This option shall vest monthly over 3 years.