TapewireFind a company

person · Reporting owner

BERTHELSEN SPENCER R

Disclosed activity across 1 company

Tapewire entity
29926
SEC CIK
0001181548

Export transaction history ↓

Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
IONIS PHARMACEUTICALS INCIONS · Entity 1182DirectorJuly 15, 2026July 17, 2026

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

IONIS PHARMACEUTICALS INC

Report date July 15, 2026 · Filed July 17, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect161,233 Reported balance After 2026-07-15 transaction · row 1
1 source row

Row 1 · 2026-07-15 · Exercise / conversion · Acquired 5,220 · Balance 161,233

F1: Acquired pursuant to vesting and release of shares in accordance with a Restricted Stock Unit award.

Restricted Stock UnitSEC Table II · derivative / convertible security · Conversion / exercise price $0.00Direct2,301 Reported balance After 2026-07-15 transaction · row 3 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 3 · 2026-07-15 · Exercise / conversion · Disposed 5,220 · Balance 2,301

F3: Each Restricted Stock Unit represents a contingent right to receive one share of Ionis common stock, or its equivalent cash value.

F4: Restricted Stock Units vest 100% on either the first anniversary of the date of grant or the next regularly scheduled annual meeting of stockholders of the Company, whichever occurs earlier, and are delivered to the reporting person on the July 15th following the vesting date. Upon vesting, the Restricted Stock Units will be paid in whole shares of Ionis common stock or cash as may be determined by the Company.

Common StockSEC Table I · non-derivativeIndirectby Daughter70 Reported balance Holding disclosure · report date 2026-07-15 · row 2 Holding and transaction disclosures are not merged.
1 source row

Row 2 · Balance 70

F2: The reporting person disclaims beneficial ownership of all securities held by his daughter, and this report should not be deemed an admission that the reporting person is the beneficial owner of such securities for purposes of Section 16 or for any other purpose.

Filing footnotes · ownership attribution and instrument terms

F1: Acquired pursuant to vesting and release of shares in accordance with a Restricted Stock Unit award.

F2: The reporting person disclaims beneficial ownership of all securities held by his daughter, and this report should not be deemed an admission that the reporting person is the beneficial owner of such securities for purposes of Section 16 or for any other purpose.

F3: Each Restricted Stock Unit represents a contingent right to receive one share of Ionis common stock, or its equivalent cash value.

F4: Restricted Stock Units vest 100% on either the first anniversary of the date of grant or the next regularly scheduled annual meeting of stockholders of the Company, whichever occurs earlier, and are delivered to the reporting person on the July 15th following the vesting date. Upon vesting, the Restricted Stock Units will be paid in whole shares of Ionis common stock or cash as may be determined by the Company.

Transaction history

JSON API
Reset

Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
July 15, 2026 Filed Jul 17, 2026 21:12 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionRestricted Stock Unit · Derivative 5,220 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0000874015-26-000244 · edgardoc.xml · derivative · entry 3

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,301

Underlying: Common Stock · 5,220 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Each Restricted Stock Unit represents a contingent right to receive one share of Ionis common stock, or its equivalent cash value.

F4 · derivative.exercise_date: Restricted Stock Units vest 100% on either the first anniversary of the date of grant or the next regularly scheduled annual meeting of stockholders of the Company, whichever occurs earlier, and are delivered to the reporting person on the July 15th following the vesting date. Upon vesting, the Restricted Stock Units will be paid in whole shares of Ionis common stock or cash as may be determined by the Company.

F4 · derivative.expiration_date: Restricted Stock Units vest 100% on either the first anniversary of the date of grant or the next regularly scheduled annual meeting of stockholders of the Company, whichever occurs earlier, and are delivered to the reporting person on the July 15th following the vesting date. Upon vesting, the Restricted Stock Units will be paid in whole shares of Ionis common stock or cash as may be determined by the Company.

Read SEC document
July 15, 2026 Filed Jul 17, 2026 21:12 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionCommon Stock 5,220 $0.00 $0.00
Disclosure

SEC source: 0000874015-26-000244 · edgardoc.xml · nonDerivative · entry 1

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 161,233

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired pursuant to vesting and release of shares in accordance with a Restricted Stock Unit award.

F1 · shares: Acquired pursuant to vesting and release of shares in accordance with a Restricted Stock Unit award.

Read SEC document
July 01, 2026 Filed Jul 6, 2026 22:44 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 GrantRestricted Stock Unit · Derivative 2,301 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0000874015-26-000226 · edgardoc.xml · derivative · entry 2

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,521

Underlying: Common Stock · 2,301 shares

Expires not disclosed

F3 · derivative.exercise_price: Each Restricted Stock Unit represents a contingent right to receive one share of Ionis common stock, or its equivalent cash value.

F1 · shares: Pursuant to the Company's Non-Employee Director Compensation Policy, these grants were adjusted downward such that the non-employee Director's annual equity compensation in 2026 totals no more than $400,000 based on the aggregate grant date fair value as determined in accordance with FASB Topic ASC 718.

F4 · derivative.exercise_date: Grant on July 1, 2026 to reporting person of Restricted Stock Unit award under the Amended and Restated Ionis Pharmaceuticals, Inc. 2002 Non-Employee Directors' Stock Option Plan. These Restricted Stock Units vest 100% on either the first anniversary of the date of grant or the next regularly scheduled annual meeting of stockholders of the Company, whichever occurs earlier, and will be delivered to the reporting person on the July 15th following the vesting date. The Restricted Stock Unit is vested as to 0 shares on July 1, 2026.

F4 · derivative.expiration_date: Grant on July 1, 2026 to reporting person of Restricted Stock Unit award under the Amended and Restated Ionis Pharmaceuticals, Inc. 2002 Non-Employee Directors' Stock Option Plan. These Restricted Stock Units vest 100% on either the first anniversary of the date of grant or the next regularly scheduled annual meeting of stockholders of the Company, whichever occurs earlier, and will be delivered to the reporting person on the July 15th following the vesting date. The Restricted Stock Unit is vested as to 0 shares on July 1, 2026.

Read SEC document
July 01, 2026 Filed Jul 6, 2026 22:44 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 GrantNon-Qualified Stock Option (right to buy) · Derivative 5,369 $0.00 Strike: $79.19 $0.00
Disclosure

SEC source: 0000874015-26-000226 · edgardoc.xml · derivative · entry 1

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,369

Underlying: Common Stock · 5,369 shares

Expires 2036-06-30

F1 · shares: Pursuant to the Company's Non-Employee Director Compensation Policy, these grants were adjusted downward such that the non-employee Director's annual equity compensation in 2026 totals no more than $400,000 based on the aggregate grant date fair value as determined in accordance with FASB Topic ASC 718.

F2 · derivative.exercise_date: Grant on July 1, 2026 to reporting person of stock options under the Amended and Restated Ionis Pharmaceuticals, Inc. 2002 Non-Employee Directors' Stock Option Plan. 100% of the shares subject to the option vest and become exercisable on either the first anniversary of the date of grant or the next regularly scheduled annual meeting of stockholders of the Company, whichever occurs earlier. The option is exercisable to 0 shares on July 1, 2026.

F2 · derivative.expiration_date: Grant on July 1, 2026 to reporting person of stock options under the Amended and Restated Ionis Pharmaceuticals, Inc. 2002 Non-Employee Directors' Stock Option Plan. 100% of the shares subject to the option vest and become exercisable on either the first anniversary of the date of grant or the next regularly scheduled annual meeting of stockholders of the Company, whichever occurs earlier. The option is exercisable to 0 shares on July 1, 2026.

Read SEC document
June 15, 2026 Filed Jun 16, 2026 21:26 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 8,000 $0.00 Strike: $24.42 $0.00
Disclosure

SEC source: 0000874015-26-000207 · edgardoc.xml · derivative · entry 4

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 8,000 shares

Expires 2026-06-30

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 15, 2026 Filed Jun 16, 2026 21:26 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 8,000 $73.49 $587,920.00
Disclosure

SEC source: 0000874015-26-000207 · edgardoc.xml · nonDerivative · entry 2

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 156,013

F1 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on September 12, 2025.

Read SEC document
June 15, 2026 Filed Jun 16, 2026 21:26 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionCommon Stock 8,000 $24.42 $195,360.00
Disclosure

SEC source: 0000874015-26-000207 · edgardoc.xml · nonDerivative · entry 1

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 164,013

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 01, 2026 Filed Jun 3, 2026 21:34 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 8,000 $0.00 Strike: $24.42 $0.00
Disclosure

SEC source: 0000874015-26-000188 · edgardoc.xml · derivative · entry 4

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 8,000

Underlying: Common Stock · 8,000 shares

Expires 2026-06-30

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 01, 2026 Filed Jun 3, 2026 21:34 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 8,000 $75.67 $605,360.00
Disclosure

SEC source: 0000874015-26-000188 · edgardoc.xml · nonDerivative · entry 2

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 156,013

F1 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on September 12, 2025.

Read SEC document
June 01, 2026 Filed Jun 3, 2026 21:34 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionCommon Stock 8,000 $24.42 $195,360.00
Disclosure

SEC source: 0000874015-26-000188 · edgardoc.xml · nonDerivative · entry 1

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 164,013

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
July 15, 2025 Filed Jul 17, 2025 20:53 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionRestricted Stock Unit · Derivative 4,079 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0000874015-25-000155 · edgardoc.xml · derivative · entry 3

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,220

Underlying: Common Stock · 4,079 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Each Restricted Stock Unit represents a contingent right to receive one share of Ionis common stock, or its equivalent cash value.

F4 · derivative.exercise_date: Restricted Stock Units vest 100% on either the first anniversary of the date of grant or the next regularly scheduled annual meeting of stockholders of the Company, whichever occurs earlier, and are delivered to the reporting person on the July 15th following the vesting date. Upon vesting, the Restricted Stock Units will be paid in whole shares of Ionis common stock or cash as may be determined by the Company.

F4 · derivative.expiration_date: Restricted Stock Units vest 100% on either the first anniversary of the date of grant or the next regularly scheduled annual meeting of stockholders of the Company, whichever occurs earlier, and are delivered to the reporting person on the July 15th following the vesting date. Upon vesting, the Restricted Stock Units will be paid in whole shares of Ionis common stock or cash as may be determined by the Company.

Read SEC document
July 15, 2025 Filed Jul 17, 2025 20:53 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionCommon Stock 4,079 $0.00 $0.00
Disclosure

SEC source: 0000874015-25-000155 · edgardoc.xml · nonDerivative · entry 1

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 156,013

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired pursuant to vesting and release of shares in accordance with a Restricted Stock Unit award.

F1 · shares: Acquired pursuant to vesting and release of shares in accordance with a Restricted Stock Unit award.

Read SEC document
July 01, 2025 Filed Jul 2, 2025 20:52 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 GrantRestricted Stock Unit · Derivative 5,220 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0000874015-25-000136 · edgardoc.xml · derivative · entry 2

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,299

Underlying: Common Stock · 5,220 shares

Expires not disclosed

F3 · derivative.exercise_price: Each Restricted Stock Unit represents a contingent right to receive one share of Ionis common stock, or its equivalent cash value.

F1 · shares: Pursuant to the Company's Non-Employee Director Compensation Policy, these grants were adjusted downward such that the non-employee Director's annual equity compensation in 2025 totals no more than $450,000 based on the aggregate grant date fair value as determined in accordance with FASB Topic ASC 718.

F4 · derivative.exercise_date: Grant on July 1, 2025 to reporting person of Restricted Stock Unit award under the Amended and Restated Ionis Pharmaceuticals, Inc. 2002 Non-Employee Directors' Stock Option Plan. These Restricted Stock Units vest 100% on either the first anniversary of the date of grant or the next regularly scheduled annual meeting of stockholders of the Company, whichever occurs earlier, and will be delivered to the reporting person on the July 15th following the vesting date. The Restricted Stock Unit is vested as to 0 shares on July 1, 2025.

F4 · derivative.expiration_date: Grant on July 1, 2025 to reporting person of Restricted Stock Unit award under the Amended and Restated Ionis Pharmaceuticals, Inc. 2002 Non-Employee Directors' Stock Option Plan. These Restricted Stock Units vest 100% on either the first anniversary of the date of grant or the next regularly scheduled annual meeting of stockholders of the Company, whichever occurs earlier, and will be delivered to the reporting person on the July 15th following the vesting date. The Restricted Stock Unit is vested as to 0 shares on July 1, 2025.

Read SEC document
July 01, 2025 Filed Jul 2, 2025 20:52 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 GrantNon-Qualified Stock Option (right to buy) · Derivative 11,518 $0.00 Strike: $39.94 $0.00
Disclosure

SEC source: 0000874015-25-000136 · edgardoc.xml · derivative · entry 1

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 11,518

Underlying: Common Stock · 11,518 shares

Expires 2035-06-30

F1 · shares: Pursuant to the Company's Non-Employee Director Compensation Policy, these grants were adjusted downward such that the non-employee Director's annual equity compensation in 2025 totals no more than $450,000 based on the aggregate grant date fair value as determined in accordance with FASB Topic ASC 718.

F2 · derivative.exercise_date: Grant on July 1, 2025 to reporting person of stock options under the Amended and Restated Ionis Pharmaceuticals, Inc. 2002 Non-Employee Directors' Stock Option Plan. 100% of the shares subject to the option vest and become exercisable on either the first anniversary of the date of grant or the next regularly scheduled annual meeting of stockholders of the Company, whichever occurs earlier. The option is exercisable to 0 shares on July 1, 2025.

F2 · derivative.expiration_date: Grant on July 1, 2025 to reporting person of stock options under the Amended and Restated Ionis Pharmaceuticals, Inc. 2002 Non-Employee Directors' Stock Option Plan. 100% of the shares subject to the option vest and become exercisable on either the first anniversary of the date of grant or the next regularly scheduled annual meeting of stockholders of the Company, whichever occurs earlier. The option is exercisable to 0 shares on July 1, 2025.

Read SEC document
July 15, 2024 Filed Jul 17, 2024 21:02 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionRestricted Stock Unit · Derivative 4,677 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0000874015-24-000177 · edgardoc.xml · derivative · entry 3

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 4,079

Underlying: Common Stock · 4,677 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Each Restricted Stock Unit represents a contingent right to receive one share of Ionis common stock, or its equivalent cash value.

F4 · derivative.exercise_date: Restricted Stock Units vest 100% on either the first anniversary of the date of grant or the next regularly scheduled annual meeting of stockholders of the Company, whichever occurs earlier, and are delivered to the reporting person on the July 15th following the vesting date. Upon vesting, the Restricted Stock Units will be paid in whole shares of Ionis common stock or cash as may be determined by the Company.

F4 · derivative.expiration_date: Restricted Stock Units vest 100% on either the first anniversary of the date of grant or the next regularly scheduled annual meeting of stockholders of the Company, whichever occurs earlier, and are delivered to the reporting person on the July 15th following the vesting date. Upon vesting, the Restricted Stock Units will be paid in whole shares of Ionis common stock or cash as may be determined by the Company.

Read SEC document
July 15, 2024 Filed Jul 17, 2024 21:02 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionCommon Stock 4,677 $0.00 $0.00
Disclosure

SEC source: 0000874015-24-000177 · edgardoc.xml · nonDerivative · entry 1

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 151,934

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired pursuant to vesting and release of shares in accordance with a Restricted Stock Unit award.

F1 · shares: Acquired pursuant to vesting and release of shares in accordance with a Restricted Stock Unit award.

Read SEC document
July 01, 2024 Filed Jul 3, 2024 18:47 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 GrantRestricted Stock Unit · Derivative 4,079 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0000874015-24-000159 · edgardoc.xml · derivative · entry 2

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,756

Underlying: Common Stock · 4,079 shares

Expires not disclosed

F3 · derivative.exercise_price: Each Restricted Stock Unit represents a contingent right to receive one share of Ionis common stock, or its equivalent cash value.

F1 · shares: Pursuant to the Company's Non-Employee Director Compensation Policy, these grants were adjusted downward such that the non-employee Director's annual equity compensation in 2024 totals no more than $450,000 based on the aggregate grant date fair value as determined in accordance with FASB Topic ASC 718.

F4 · derivative.exercise_date: Grant on July 1, 2024 to reporting person of Restricted Stock Unit award under the Amended and Restated Ionis Pharmaceuticals, Inc. 2002 Non-Employee Directors' Stock Option Plan. These Restricted Stock Units vest 100% on either the first anniversary of the date of grant or the next regularly scheduled annual meeting of stockholders of the Company, whichever occurs earlier, and will be delivered to the reporting person on the July 15th following the vesting date. The Restricted Stock Unit is vested as to 0 shares on July 1, 2024.

F4 · derivative.expiration_date: Grant on July 1, 2024 to reporting person of Restricted Stock Unit award under the Amended and Restated Ionis Pharmaceuticals, Inc. 2002 Non-Employee Directors' Stock Option Plan. These Restricted Stock Units vest 100% on either the first anniversary of the date of grant or the next regularly scheduled annual meeting of stockholders of the Company, whichever occurs earlier, and will be delivered to the reporting person on the July 15th following the vesting date. The Restricted Stock Unit is vested as to 0 shares on July 1, 2024.

Read SEC document
July 01, 2024 Filed Jul 3, 2024 18:47 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 GrantNon-Qualified Stock Option (right to buy) · Derivative 10,111 $0.00 Strike: $47.11 $0.00
Disclosure

SEC source: 0000874015-24-000159 · edgardoc.xml · derivative · entry 1

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,111

Underlying: Common Stock · 10,111 shares

Expires 2034-06-30

F1 · shares: Pursuant to the Company's Non-Employee Director Compensation Policy, these grants were adjusted downward such that the non-employee Director's annual equity compensation in 2024 totals no more than $450,000 based on the aggregate grant date fair value as determined in accordance with FASB Topic ASC 718.

F2 · derivative.exercise_date: Grant on July 1, 2024 to reporting person of stock options under the Amended and Restated Ionis Pharmaceuticals, Inc. 2002 Non-Employee Directors' Stock Option Plan. 100% of the shares subject to the option vest and become exercisable on either the first anniversary of the date of grant or the next regularly scheduled annual meeting of stockholders of the Company, whichever occurs earlier. The option is exercisable to 0 shares on July 1, 2024.

F2 · derivative.expiration_date: Grant on July 1, 2024 to reporting person of stock options under the Amended and Restated Ionis Pharmaceuticals, Inc. 2002 Non-Employee Directors' Stock Option Plan. 100% of the shares subject to the option vest and become exercisable on either the first anniversary of the date of grant or the next regularly scheduled annual meeting of stockholders of the Company, whichever occurs earlier. The option is exercisable to 0 shares on July 1, 2024.

Read SEC document
June 17, 2024 Filed Jun 20, 2024 21:52 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 16,000 $0.00 Strike: $35.53 $0.00
Disclosure

SEC source: 0000874015-24-000149 · edgardoc.xml · derivative · entry 4

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 16,000 shares

Expires 2024-06-30

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 17, 2024 Filed Jun 20, 2024 21:52 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 16,000 $40.29 $644,640.00
Disclosure

SEC source: 0000874015-24-000149 · edgardoc.xml · nonDerivative · entry 2

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 147,257

Read SEC document
June 17, 2024 Filed Jun 20, 2024 21:52 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionCommon Stock 16,000 $35.53 $568,480.00
Disclosure

SEC source: 0000874015-24-000149 · edgardoc.xml · nonDerivative · entry 1

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 163,257

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
July 17, 2023 Filed Jul 19, 2023 22:05 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionRestricted Stock Unit · Derivative 5,333 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0000874015-23-000172 · edgardoc.xml · derivative · entry 5

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 4,677

Underlying: Common Stock · 5,333 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Each Restricted Stock Unit represents a contingent right to receive one share of Ionis common stock, or its equivalent cash value.

F5 · derivative.exercise_date: Restricted Stock Units vest 100% on either the first anniversary of the date of grant or the next regularly scheduled annual meeting of stockholders of the Company, whichever occurs earlier, and are delivered to the reporting person on the July 15th following the vesting date. Upon vesting, the Restricted Stock Units will be paid in whole shares of Ionis common stock or cash as may be determined by the Company.

F5 · derivative.expiration_date: Restricted Stock Units vest 100% on either the first anniversary of the date of grant or the next regularly scheduled annual meeting of stockholders of the Company, whichever occurs earlier, and are delivered to the reporting person on the July 15th following the vesting date. Upon vesting, the Restricted Stock Units will be paid in whole shares of Ionis common stock or cash as may be determined by the Company.

Read SEC document
July 17, 2023 Filed Jul 19, 2023 22:05 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionRestricted Stock Unit · Derivative 1,777 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0000874015-23-000172 · edgardoc.xml · derivative · entry 4

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,010

Underlying: Common Stock · 1,777 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Each Restricted Stock Unit represents a contingent right to receive one share of Ionis common stock, or its equivalent cash value.

F4 · derivative.exercise_date: Restricted Stock Units vest in four equal annual installments. Upon vesting, the restricted stock units will be paid out in whole shares of Ionis common stock or cash as may be determined by the Company.

F4 · derivative.expiration_date: Restricted Stock Units vest in four equal annual installments. Upon vesting, the restricted stock units will be paid out in whole shares of Ionis common stock or cash as may be determined by the Company.

Read SEC document
July 17, 2023 Filed Jul 19, 2023 22:05 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionCommon Stock 5,333 $0.00 $0.00
Disclosure

SEC source: 0000874015-23-000172 · edgardoc.xml · nonDerivative · entry 2

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 147,257

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired pursuant to vesting and release of shares in accordance with a Restricted Stock Unit award.

F1 · shares: Acquired pursuant to vesting and release of shares in accordance with a Restricted Stock Unit award.

Read SEC document
July 17, 2023 Filed Jul 19, 2023 22:05 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionCommon Stock 1,777 $0.00 $0.00
Disclosure

SEC source: 0000874015-23-000172 · edgardoc.xml · nonDerivative · entry 1

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 141,924

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired pursuant to vesting and release of shares in accordance with a Restricted Stock Unit award.

F1 · shares: Acquired pursuant to vesting and release of shares in accordance with a Restricted Stock Unit award.

Read SEC document
July 03, 2023 Filed Jul 6, 2023 21:13 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 GrantRestricted Stock Unit · Derivative 4,677 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0000874015-23-000154 · edgardoc.xml · derivative · entry 2

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 11,787

Underlying: Common Stock · 4,677 shares

Expires not disclosed

F3 · derivative.exercise_price: Each Restricted Stock Unit represents a contingent right to receive one share of Ionis common stock, or its equivalent cash value.

F1 · shares: Pursuant to the Company's Non-Employee Director Compensation Policy, these grants were adjusted downward such that the non-employee Director's annual equity compensation in 2023 totals no more than $450,000 based on the aggregate grant date fair value as determined in accordance with FASB Topic ASC 718.

F4 · derivative.exercise_date: Grant on July 3, 2023 to reporting person of Restricted Stock Unit award under the Amended and Restated Ionis Pharmaceuticals, Inc. 2002 Non-Employee Directors' Stock Option Plan. These Restricted Stock Units vest 100% on either the first anniversary of the date of grant or the next regularly scheduled annual meeting of stockholders of the Company, whichever occurs earlier, and will be delivered to the reporting person on the July 15th following the vesting date. The Restricted Stock Unit is vested as to 0 shares on July 3, 2023.

F4 · derivative.expiration_date: Grant on July 3, 2023 to reporting person of Restricted Stock Unit award under the Amended and Restated Ionis Pharmaceuticals, Inc. 2002 Non-Employee Directors' Stock Option Plan. These Restricted Stock Units vest 100% on either the first anniversary of the date of grant or the next regularly scheduled annual meeting of stockholders of the Company, whichever occurs earlier, and will be delivered to the reporting person on the July 15th following the vesting date. The Restricted Stock Unit is vested as to 0 shares on July 3, 2023.

Read SEC document
July 03, 2023 Filed Jul 6, 2023 21:13 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 GrantNon-Qualified Stock Option (right to buy) · Derivative 10,321 $0.00 Strike: $41.08 $0.00
Disclosure

SEC source: 0000874015-23-000154 · edgardoc.xml · derivative · entry 1

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,321

Underlying: Common Stock · 10,321 shares

Expires 2033-07-02

F1 · shares: Pursuant to the Company's Non-Employee Director Compensation Policy, these grants were adjusted downward such that the non-employee Director's annual equity compensation in 2023 totals no more than $450,000 based on the aggregate grant date fair value as determined in accordance with FASB Topic ASC 718.

F2 · derivative.exercise_date: Grant on July 3, 2023 to reporting person of stock options under the Amended and Restated Ionis Pharmaceuticals, Inc. 2002 Non-Employee Directors' Stock Option Plan. 100% of the shares subject to the option vest and become exercisable on either the first anniversary of the date of grant or the next regularly scheduled annual meeting of stockholders of the Company, whichever occurs earlier. The option is exercisable to 0 shares on July 3, 2023.

F2 · derivative.expiration_date: Grant on July 3, 2023 to reporting person of stock options under the Amended and Restated Ionis Pharmaceuticals, Inc. 2002 Non-Employee Directors' Stock Option Plan. 100% of the shares subject to the option vest and become exercisable on either the first anniversary of the date of grant or the next regularly scheduled annual meeting of stockholders of the Company, whichever occurs earlier. The option is exercisable to 0 shares on July 3, 2023.

Read SEC document
June 20, 2023 Filed Jun 22, 2023 21:17 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 11,250 $0.00 Strike: $28.47 $0.00
Disclosure

SEC source: 0000874015-23-000144 · edgardoc.xml · derivative · entry 3

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 11,250 shares

Expires 2023-06-30

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 20, 2023 Filed Jun 22, 2023 21:17 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionCommon Stock 11,250 $28.47 $320,287.50
Disclosure

SEC source: 0000874015-23-000144 · edgardoc.xml · nonDerivative · entry 1

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 140,147

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired as a result of exercising a stock option that was scheduled to expire on 6/30/2023

F1 · shares: Acquired as a result of exercising a stock option that was scheduled to expire on 6/30/2023

Read SEC document
July 15, 2022 Filed Jul 19, 2022 23:19 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionRestricted Stock Unit · Derivative 2,665 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0000874015-22-000136 · edgardoc.xml · derivative · entry 5

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,110

Underlying: Common Stock · 2,665 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_price: Each Restricted Stock Unit represents a contingent right to receive one share of Ionis common stock, or its equivalent cash value.

F6 · derivative.exercise_date: Restricted Stock Units vest in four equal annual installments and are delivered to the reporting person on the July 15th following the vesting date. Upon vesting, the Restricted Stock Units will be paid in whole shares of Ionis common stock or cash as may be determined by the Company.

F6 · derivative.expiration_date: Restricted Stock Units vest in four equal annual installments and are delivered to the reporting person on the July 15th following the vesting date. Upon vesting, the Restricted Stock Units will be paid in whole shares of Ionis common stock or cash as may be determined by the Company.

Read SEC document
July 15, 2022 Filed Jul 19, 2022 23:19 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionRestricted Stock Unit · Derivative 5,333 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0000874015-22-000136 · edgardoc.xml · derivative · entry 4

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,775

Underlying: Common Stock · 5,333 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_price: Each Restricted Stock Unit represents a contingent right to receive one share of Ionis common stock, or its equivalent cash value.

F5 · derivative.exercise_date: Restricted Stock Units vest 100% on either the first anniversary of the date of grant or the next regularly scheduled annual meeting of stockholders of the Company, whichever occurs earlier, and are delivered to the reporting person on the July 15th following the vesting date. Upon vesting, the Restricted Stock Units will be paid in whole shares of Ionis common stock or cash as may be determined by the Company.

F5 · derivative.expiration_date: Restricted Stock Units vest 100% on either the first anniversary of the date of grant or the next regularly scheduled annual meeting of stockholders of the Company, whichever occurs earlier, and are delivered to the reporting person on the July 15th following the vesting date. Upon vesting, the Restricted Stock Units will be paid in whole shares of Ionis common stock or cash as may be determined by the Company.

Read SEC document
July 15, 2022 Filed Jul 19, 2022 23:19 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionCommon Stock 2,665 $0.00 $0.00
Disclosure

SEC source: 0000874015-22-000136 · edgardoc.xml · nonDerivative · entry 2

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 128,897

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · kind: Acquired pursuant to vesting and release of shares in accordance with Restricted Stock Unit awards.

F2 · shares: Acquired pursuant to vesting and release of shares in accordance with Restricted Stock Unit awards.

Read SEC document
July 15, 2022 Filed Jul 19, 2022 23:19 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionCommon Stock 5,333 $0.00 $0.00
Disclosure

SEC source: 0000874015-22-000136 · edgardoc.xml · nonDerivative · entry 1

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 126,232

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired pursuant to vesting and release of shares in accordance with a Restricted Stock Unit award.

F1 · shares: Acquired pursuant to vesting and release of shares in accordance with a Restricted Stock Unit award.

Read SEC document
July 01, 2022 Filed Jul 6, 2022 21:23 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 GrantRestricted Stock Unit · Derivative 5,333 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0000874015-22-000118 · edgardoc.xml · derivative · entry 2

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,108

Underlying: Common Stock · 5,333 shares

Expires not disclosed

F2 · derivative.exercise_price: Each Restricted Stock Unit represents a contingent right to receive one share of Ionis common stock, or its equivalent cash value.

F3 · derivative.exercise_date: Grant on July 1, 2022 to reporting person of Restricted Stock Unit award under the Amended and Restated Ionis Pharmaceuticals, Inc. 2002 Non-Employee Directors' Stock Option Plan. These Restricted Stock Units vest 100% on either the first anniversary of the date of grant or the next regularly scheduled annual meeting of stockholders of the Company, whichever occurs earlier, and will be delivered to the reporting person on the July 15th following the vesting date. The Restricted Stock Unit is vested as to 0 shares on July 1, 2022.

F3 · derivative.expiration_date: Grant on July 1, 2022 to reporting person of Restricted Stock Unit award under the Amended and Restated Ionis Pharmaceuticals, Inc. 2002 Non-Employee Directors' Stock Option Plan. These Restricted Stock Units vest 100% on either the first anniversary of the date of grant or the next regularly scheduled annual meeting of stockholders of the Company, whichever occurs earlier, and will be delivered to the reporting person on the July 15th following the vesting date. The Restricted Stock Unit is vested as to 0 shares on July 1, 2022.

Read SEC document
July 01, 2022 Filed Jul 6, 2022 21:23 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 GrantNon-Qualified Stock Option (right to buy) · Derivative 12,000 $0.00 Strike: $38.06 $0.00
Disclosure

SEC source: 0000874015-22-000118 · edgardoc.xml · derivative · entry 1

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,000

Underlying: Common Stock · 12,000 shares

Expires 2032-06-30

F1 · derivative.exercise_date: Grant on July 1, 2022 to reporting person of stock options under the Amended and Restated Ionis Pharmaceuticals, Inc. 2002 Non-Employee Directors' Stock Option Plan. 100% of the shares subject to the option vest and become exercisable on either the first anniversary of the date of grant or the next regularly scheduled annual meeting of stockholders of the Company, whichever occurs earlier. The option is exercisable to 0 shares on July 1, 2022.

F1 · derivative.expiration_date: Grant on July 1, 2022 to reporting person of stock options under the Amended and Restated Ionis Pharmaceuticals, Inc. 2002 Non-Employee Directors' Stock Option Plan. 100% of the shares subject to the option vest and become exercisable on either the first anniversary of the date of grant or the next regularly scheduled annual meeting of stockholders of the Company, whichever occurs earlier. The option is exercisable to 0 shares on July 1, 2022.

Read SEC document
June 07, 2022 Filed Jun 9, 2022 21:53 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 11,250 $0.00 Strike: $12.94 $0.00
Disclosure

SEC source: 0000874015-22-000106 · edgardoc.xml · derivative · entry 3

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 11,250 shares

Expires 2022-07-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 07, 2022 Filed Jun 9, 2022 21:53 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionCommon Stock 11,250 $12.94 $145,575.00
Disclosure

SEC source: 0000874015-22-000106 · edgardoc.xml · nonDerivative · entry 1

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 120,899

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired as a result of exercising a stock option that was scheduled to expire on 7/1/2022.

F1 · shares: Acquired as a result of exercising a stock option that was scheduled to expire on 7/1/2022.

Read SEC document
July 15, 2021 Filed Jul 20, 2021 00:13 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionRestricted Stock Unit · Derivative 1,778 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0000874015-21-000132 · edgardoc.xml · derivative · entry 9

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,775

Underlying: Common Stock · 1,778 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Each Restricted Stock Unit represents a contingent right to receive one share of Ionis common stock, or its equivalent cash value.

F5 · derivative.exercise_date: Restricted Stock Units vest in four equal annual installments and are delivered to the reporting person on the July 15th following the vesting date. Upon vesting, the Restricted Stock Units will be paid in whole shares of Ionis common stock or cash as may be determined by the Company.

F5 · derivative.expiration_date: Restricted Stock Units vest in four equal annual installments and are delivered to the reporting person on the July 15th following the vesting date. Upon vesting, the Restricted Stock Units will be paid in whole shares of Ionis common stock or cash as may be determined by the Company.

Read SEC document
July 15, 2021 Filed Jul 20, 2021 00:13 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionRestricted Stock Unit · Derivative 666 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0000874015-21-000132 · edgardoc.xml · derivative · entry 8

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,553

Underlying: Common Stock · 666 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Each Restricted Stock Unit represents a contingent right to receive one share of Ionis common stock, or its equivalent cash value.

F5 · derivative.exercise_date: Restricted Stock Units vest in four equal annual installments and are delivered to the reporting person on the July 15th following the vesting date. Upon vesting, the Restricted Stock Units will be paid in whole shares of Ionis common stock or cash as may be determined by the Company.

F5 · derivative.expiration_date: Restricted Stock Units vest in four equal annual installments and are delivered to the reporting person on the July 15th following the vesting date. Upon vesting, the Restricted Stock Units will be paid in whole shares of Ionis common stock or cash as may be determined by the Company.

Read SEC document
July 15, 2021 Filed Jul 20, 2021 00:13 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionRestricted Stock Unit · Derivative 889 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0000874015-21-000132 · edgardoc.xml · derivative · entry 7

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,219

Underlying: Common Stock · 889 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Each Restricted Stock Unit represents a contingent right to receive one share of Ionis common stock, or its equivalent cash value.

F5 · derivative.exercise_date: Restricted Stock Units vest in four equal annual installments and are delivered to the reporting person on the July 15th following the vesting date. Upon vesting, the Restricted Stock Units will be paid in whole shares of Ionis common stock or cash as may be determined by the Company.

F5 · derivative.expiration_date: Restricted Stock Units vest in four equal annual installments and are delivered to the reporting person on the July 15th following the vesting date. Upon vesting, the Restricted Stock Units will be paid in whole shares of Ionis common stock or cash as may be determined by the Company.

Read SEC document
July 15, 2021 Filed Jul 20, 2021 00:13 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionRestricted Stock Unit · Derivative 5,333 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0000874015-21-000132 · edgardoc.xml · derivative · entry 6

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,108

Underlying: Common Stock · 5,333 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Each Restricted Stock Unit represents a contingent right to receive one share of Ionis common stock, or its equivalent cash value.

F4 · derivative.exercise_date: Restricted Stock Units vest 100% on either the first anniversary of the date of grant or the next regularly scheduled annual meeting of stockholders of the Company, whichever occurs earlier, and are delivered to the reporting person on the July 15th following the vesting date. Upon vesting, the Restricted Stock Units will be paid in whole shares of Ionis common stock or cash as may be determined by the Company.

F4 · derivative.expiration_date: Restricted Stock Units vest 100% on either the first anniversary of the date of grant or the next regularly scheduled annual meeting of stockholders of the Company, whichever occurs earlier, and are delivered to the reporting person on the July 15th following the vesting date. Upon vesting, the Restricted Stock Units will be paid in whole shares of Ionis common stock or cash as may be determined by the Company.

Read SEC document
July 15, 2021 Filed Jul 20, 2021 00:13 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionCommon Stock 1,778 $0.00 $0.00
Disclosure

SEC source: 0000874015-21-000132 · edgardoc.xml · nonDerivative · entry 4

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 109,649

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired pursuant to vesting and release of shares pursuant to a Restricted Stock Unit Award.

F1 · shares: Acquired pursuant to vesting and release of shares pursuant to a Restricted Stock Unit Award.

Read SEC document
July 15, 2021 Filed Jul 20, 2021 00:13 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionCommon Stock 666 $0.00 $0.00
Disclosure

SEC source: 0000874015-21-000132 · edgardoc.xml · nonDerivative · entry 3

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 107,871

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired pursuant to vesting and release of shares pursuant to a Restricted Stock Unit Award.

F1 · shares: Acquired pursuant to vesting and release of shares pursuant to a Restricted Stock Unit Award.

Read SEC document
July 15, 2021 Filed Jul 20, 2021 00:13 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionCommon Stock 889 $0.00 $0.00
Disclosure

SEC source: 0000874015-21-000132 · edgardoc.xml · nonDerivative · entry 2

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 107,205

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired pursuant to vesting and release of shares pursuant to a Restricted Stock Unit Award.

F1 · shares: Acquired pursuant to vesting and release of shares pursuant to a Restricted Stock Unit Award.

Read SEC document
July 15, 2021 Filed Jul 20, 2021 00:13 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionCommon Stock 5,333 $0.00 $0.00
Disclosure

SEC source: 0000874015-21-000132 · edgardoc.xml · nonDerivative · entry 1

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 106,316

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired pursuant to vesting and release of shares pursuant to a Restricted Stock Unit Award.

F1 · shares: Acquired pursuant to vesting and release of shares pursuant to a Restricted Stock Unit Award.

Read SEC document
July 01, 2021 Filed Jul 6, 2021 21:50 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 GrantRestricted Stock Unit · Derivative 5,333 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0000874015-21-000110 · edgardoc.xml · derivative · entry 2

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,441

Underlying: Common Stock · 5,333 shares

Expires not disclosed

F2 · derivative.exercise_price: Each Restricted Stock Unit represents a contingent right to receive one share of Ionis common stock, or its equivalent cash value.

F3 · derivative.exercise_date: Grant of July 1, 2021 to reporting person of Restricted Stock Unit award under the Amended and Restated Ionis Pharmaceuticals, Inc. 2002 Non-Employee Directors' Stock Option Plan. These Restricted Stock Units vest 100% on either the first anniversary of the date of grant or the next regularly scheduled annual meeting of stockholders of the Company, whichever occurs earlier, and will be delivered to the reporting person on the July 15th following the vesting date. The Restricted Stock Unit is vested as to 0 shares on July 1, 2021.

F3 · derivative.expiration_date: Grant of July 1, 2021 to reporting person of Restricted Stock Unit award under the Amended and Restated Ionis Pharmaceuticals, Inc. 2002 Non-Employee Directors' Stock Option Plan. These Restricted Stock Units vest 100% on either the first anniversary of the date of grant or the next regularly scheduled annual meeting of stockholders of the Company, whichever occurs earlier, and will be delivered to the reporting person on the July 15th following the vesting date. The Restricted Stock Unit is vested as to 0 shares on July 1, 2021.

Read SEC document
July 01, 2021 Filed Jul 6, 2021 21:50 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 GrantNon-Qualified Stock Option (right to buy) · Derivative 12,000 $0.00 Strike: $40.05 $0.00
Disclosure

SEC source: 0000874015-21-000110 · edgardoc.xml · derivative · entry 1

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,000

Underlying: Common Stock · 12,000 shares

Expires 2031-06-30

F1 · derivative.exercise_date: Grant of July 1, 2021 to reporting person of stock options under the Amended and Restated Ionis Pharmaceuticals, Inc. 2002 Non-Employee Directors' Stock Option Plan. 100% of the shares subject to the option vest and become exercisable on either the first anniversary of the date of grant or the next regularly scheduled annual meeting of stockholders of the Company, whichever occurs earlier. The option is exercisable to 0 shares on July 1, 2021.

F1 · derivative.expiration_date: Grant of July 1, 2021 to reporting person of stock options under the Amended and Restated Ionis Pharmaceuticals, Inc. 2002 Non-Employee Directors' Stock Option Plan. 100% of the shares subject to the option vest and become exercisable on either the first anniversary of the date of grant or the next regularly scheduled annual meeting of stockholders of the Company, whichever occurs earlier. The option is exercisable to 0 shares on July 1, 2021.

Read SEC document
June 23, 2021 Filed Jun 25, 2021 21:19 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 15,000 $0.00 Strike: $9.30 $0.00
Disclosure

SEC source: 0000874015-21-000088 · edgardoc.xml · derivative · entry 4

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 15,000 shares

Expires 2021-06-30

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 23, 2021 Filed Jun 25, 2021 21:19 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 SaleCommon Stock 15,000 $37.74 $566,100.00
Disclosure

SEC source: 0000874015-21-000088 · edgardoc.xml · nonDerivative · entry 2

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 100,983

F2 · shares: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on March 12, 2021.

Read SEC document
June 23, 2021 Filed Jun 25, 2021 21:19 UTC IONIS PHARMACEUTICALS INC IONS · Entity 1182 Exercise / conversionCommon Stock 15,000 $9.30 $139,500.00
Disclosure

SEC source: 0000874015-21-000088 · edgardoc.xml · nonDerivative · entry 1

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 115,983

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: Acquired as a result of exercising a stock option that was scheduled to expire on June 30, 2021. The purchase reported on this Form 4 was effected pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person March 12, 2021.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.