HILLEMAN JERYL L

SEC source: 0001610717-26-000428 · form4.xml · nonDerivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,869

F1 · shares: Represents restricted stock units ("RSUs") that were granted pursuant to the Issuer's Non-Employee Director Compensation Program (the "Program") in lieu of retainer fees. Each RSU represents the right to receive one (1) share of Common Stock, with settlement to take place either (i) on a date selected by the Reporting Person pursuant to the Program or (ii) as otherwise provided by the Program.

SEC source: 0001610717-26-000324 · form4.xml · nonDerivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 26,519

F1 · shares: Represents restricted stock units ("RSUs") that were granted pursuant to the Issuer's Non-Employee Director Compensation Program (the "Program") in lieu of retainer fees. Each RSU represents the right to receive one (1) share of Common Stock, with settlement to take place either (i) on a date selected by the Reporting Person pursuant to the Program or (ii) as otherwise provided by the Program.

SEC source: 0001610717-26-000340 · form4a.xml · nonDerivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 26,655

F1 · shares: Represents restricted stock units ("RSUs") that were granted pursuant to the Issuer's Non-Employee Director Compensation Program (the "Program") in lieu of retainer fees. Each RSU represents the right to receive one (1) share of Common Stock, with settlement to take place either (i) on a date selected by the Reporting Person pursuant to the Program or (ii) as otherwise provided by the Program.

F2 · shares: This Form 4/A is being filed solely to correct the number of RSUs reported as granted on July 5, 2026, and the total number of shares beneficially owned by the Reporting Person. Due to an administrative error, the original Form 4 filing understated the number of RSUs that were granted pursuant to the Program. This amendment corrects the error to reflect the actual number of RSUs granted and the shares beneficially owned by the Reporting Person following the grant.

F2 · balance_after: This Form 4/A is being filed solely to correct the number of RSUs reported as granted on July 5, 2026, and the total number of shares beneficially owned by the Reporting Person. Due to an administrative error, the original Form 4 filing understated the number of RSUs that were granted pursuant to the Program. This amendment corrects the error to reflect the actual number of RSUs granted and the shares beneficially owned by the Reporting Person following the grant.

SEC source: 0001610717-26-000254 · form4.xml · nonDerivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 25,220

F1 · shares: Constitute restricted stock units ("RSUs") for which the Reporting Person is entitled to receive one (1) share of Common Stock for each RSU upon vesting. 100% of the RSUs will fully vest on the earlier of (i) the first anniversary of the grant date or (ii) the date of the 2027 Annual Meeting of the Issuer's stockholders, subject to continued service through such vesting date.

SEC source: 0001216628-26-000003 · primary_doc.xml · nonDerivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 43,772

F1 · shares: Reflects shares issuable on the settlement of restricted stock units granted to the Reporting Person. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock. The shares subject to the restricted stock unit will vest 100% upon the earlier of (i) the next annual general meeting of the stockholders of the Company or (ii) the date one year from the Vesting Commencement Date, subject to the Reporting Person's continuous service as a member of the Company's Board of Directors until such date.

F2 · balance_after: Includes 10,957 shares issuable on the settlement of restricted stock units granted to the Reporting Person. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001216628-26-000002 · primarydocument.xml · derivative · entry 2

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,999

Underlying: Ordinary Shares · 16,999 shares

Expires 2036-06-03

F2 · derivative.exercise_date: Options to buy ordinary shares will fully vest and become exercisable on the earlier of the following dates: (i) the first anniversary of the grant date or (ii) the day immediately preceding the Company's 2027 annual general meeting of shareholders.

SEC source: 0001216628-26-000002 · primarydocument.xml · nonDerivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 25,471

F1 · security: Represents restricted stock units that are scheduled to vest 100% on the earlier of the following dates: (i) the first anniversary of the grant date or (ii) the day immediately preceding the Company's 2027 annual general meeting of shareholders.

SEC source: 0001216628-26-000001 · primarydocument.xml · nonDerivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 13,861

F1 · shares: Represents the number of shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of Restricted Stock Units. This sale is mandated by the issuer's award agreement under its equity incentive plans to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the reporting person.

F2 · price: This transaction was executed in multiple trades at prices ranging from $15.65 USD to $15.88 USD; the price reported above reflects the weighted average sale price.

SEC source: 0001610717-26-000143 · form4.xml · nonDerivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,338

F1 · shares: Represents restricted stock units ("RSUs") that were granted pursuant to the Issuer's Non-Employee Director Compensation Program (the "Program") in lieu of retainer fees. Each RSU represents the right to receive one (1) share of Common Stock, with settlement to take place either (i) on a date selected by the Reporting Person pursuant to the Program or (ii) as otherwise provided by the Program.

SEC source: 0001610717-26-000004 · form4.xml · nonDerivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 12,794

F1 · shares: Represents restricted stock units ("RSUs") that were granted pursuant to the Issuer's Non-Employee Director Compensation Program (the "Program") in lieu of retainer fees. Each RSU represents the right to receive one (1) share of Common Stock, with settlement to take place either (i) on a date selected by the Reporting Person pursuant to the Program or (ii) as otherwise provided by the Program.

SEC source: 0001628280-25-044510 · wk-form4_1759869683.xml · nonDerivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 11,238

F1 · shares: Represents restricted stock units ("RSUs") that were granted pursuant to the Issuer's Non-Employee Director Compensation Program (the "Program") in lieu of retainer fees. Each RSU represents the right to receive one (1) share of Common Stock, with settlement to take place either (i) on a date selected by the Reporting Person pursuant to the Program or (ii) as otherwise provided by the Program.

SEC source: 0001610717-25-000425 · form4.xml · nonDerivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 11,193

F1 · shares: Represents restricted stock units ("RSUs") that were granted pursuant to the Issuer's Non-Employee Director Compensation Program (the "Program") in lieu of retainer fees. Each RSU represents the right to receive one (1) share of Common Stock, with settlement to take place either (i) on a date selected by the Reporting Person pursuant to the Program or (ii) as otherwise provided by the Program.

F2 · shares: The original Form 4 filed by the Reporting Person inadvertently overstated the amount of securities acquired and beneficially owned by 45 shares. This Form 4 amendment is being filed to correct the aforementioned errors.

F2 · balance_after: The original Form 4 filed by the Reporting Person inadvertently overstated the amount of securities acquired and beneficially owned by 45 shares. This Form 4 amendment is being filed to correct the aforementioned errors.

SEC source: 0001193125-25-206253 · ownership.xml · nonDerivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

F1 · price: In connection with that certain Agreement and Plan of Merger, dated as of August 4, 2025 (the "Merger Agreement"), by and among the Issuer, XOMA Royalty Corporation ("Parent") and XRA 4 Corp., a wholly owned subsidiary of Parent ("Merger Sub" and together with Parent, the "Purchasers"), the Purchasers completed a tender offer to acquire all of the issued and outstanding shares of Common Stock of the Issuer in exchange for (a) $1.95 in cash per share (the "Cash Amount"), plus (b) one contingent value right ("CVR") representing the right to receive certain contingent cash payments equal to the "CVR Proceeds" as further described in that certain CVR Agreement entered into between the Purchasers and a representative to the CVR holders. After completion of the tender offer, Merger Sub merged with and into the Issuer, effective as of September 17, 2025 (the "Effective Time"), with the Issuer continuing as the surviving corporation and as a wholly owned subsidiary of Parent.

F2 · price: Pursuant to the terms of the Merger Agreement, immediately prior to the Effective Time, each outstanding restricted stock unit ("RSU") immediately vested in full and was canceled in exchange for the right to receive (a) an amount in cash, without interest, equal to the product obtained by multiplying (x) the Cash Amount by (y) the number of shares underlying such RSU at the Effective Time and (b) one CVR for each share underlying such RSU.

SEC source: 0001610717-25-000281 · form4.xml · nonDerivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,112

F1 · shares: Represents restricted stock units ("RSUs") that were granted pursuant to the Issuer's Non-Employee Director Compensation Program (the "Program") in lieu of retainer fees. Each RSU represents the right to receive one (1) share of Common Stock, with settlement to take place either (i) on a date selected by the Reporting Person pursuant to the Program or (ii) as otherwise provided by the Program.

SEC source: 0000950170-25-089951 · ownership.xml · nonDerivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 59,224

F1 · shares: The Restricted Stock Units ("RSUs") were granted on June 23, 2025 pursuant to the Registrant's Non-Employee Director Compensation Program. 100% of the total number of RSUs granted shall vest on the first to occur of (i) the first anniversary of the date of grant or (ii) a Change in Control (as defined in the Registrant's 2022 Incentive Award Plan), in each case, subject to the non-employee director continuing in service on the Registrant's board of directors through such vesting date.

SEC source: 0001562180-25-004610 · primarydocument.xml · nonDerivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 32,815

F1 · shares: Reflects shares issuable on the settlement of restricted stock units granted to the Reporting Person. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock. The shares subject to the restricted stock unit will vest 100% upon the earlier of (i) the next annual general meeting of the stockholders of the Company or (ii) the date one year from the Vesting Commencement Date, subject to the Reporting Person's continuous service as a member of the Company's Board of Directors until such date.

F2 · balance_after: Includes 8,675 shares issuable on the settlement of restricted stock units granted to the Reporting Person. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001610717-25-000178 · form4.xml · nonDerivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,736

F1 · shares: Constitute restricted stock units ("RSUs") for which the Reporting Person is entitled to receive one (1) share of Common Stock for each RSU upon vesting. 100% of the RSUs will fully vest on the first anniversary of June 5, 2025.

SEC source: 0001562180-25-004559 · primarydocument.xml · derivative · entry 2

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,697

Underlying: Ordinary Shares · 16,697 shares

Expires 2035-06-04

F2 · derivative.exercise_date: Options to buy ordinary shares will fully vest and become exercisable on the earlier of the following dates: (i) the first anniversary of the grant date or (ii) the day immediately preceding the Company's 2026 annual general meeting of shareholders.

SEC source: 0001562180-25-004559 · primarydocument.xml · nonDerivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,806

F1 · security: Represents restricted stock units that are scheduled to vest 100% on the earlier of the following dates: (i) the first anniversary of the grant date or (ii) the day immediately preceding the Company's 2026 annual general meeting of shareholders.

SEC source: 0001562180-25-004431 · primarydocument.xml · nonDerivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,591

F1 · shares: Represents the number of shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of Restricted Stock Units. This sale is mandated by the issuer's award agreement under its equity incentive plans to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the reporting person.

F2 · price: This transaction was executed in multiple trades at prices ranging from $17.1025 USD to $17.50 USD; the price reported above reflects the weighted average sale price.

SEC source: 0001628280-24-045300 · wk-form4_1730841420.xml · derivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 40,000

Underlying: COMMON STOCK · 14,673 shares

Expires 2031-10-23

F1 · derivative.exercise_date: All shares vest on the earlier of 12 months from grant date, or on the day of the 2025 annual stockholder meeting, subject to the Reporting Person continuing to be a service provider of the Company.

F2 · derivative.expiration_date: The expiration date is subject to earlier expiration upon the termination of the Reporting Person's service with the Company.

SEC source: 0001628280-24-031994 · wk-form4_1721171156.xml · derivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 25,327

Underlying: COMMON STOCK · 25,327 shares

Expires 2031-07-12

F1 · derivative.exercise_date: The stock option vests in equal installments on each of the one-year, two-year, and three-year anniversaries of the grant date.

SEC source: 0001562180-24-005327 · primarydocument.xml · nonDerivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 24,140

F1 · shares: Reflects shares issuable on the settlement of restricted stock units granted to the Reporting Person. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock. The shares subject to the restricted stock unit will vest 100% upon the earlier of (i) the next annual general meeting of the stockholders of the Company or (ii) the date one year from the Vesting Commencement Date, subject to the Reporting Person's continuous service as a member of the Company's Board of Directors until such date.

F2 · balance_after: Includes 13,657 shares issuable on the settlement of restricted stock units granted to the Reporting Person. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0000950170-25-060558 · ownership.xml · derivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 22,500

Underlying: Common Stock · 22,500 shares

Expires 2034-06-05

F1 · derivative.exercise_date: The option was granted pursuant to the Registrant's non-employee director compensation program. The option shall vest and/or become exercisable on the first to occur of (i) the first anniversary of the grant date or (ii) the next occurring annual meeting of our stockholders, in each case, subject to the non-employee director continuing in service on our board of directors through such vesting dates.

SEC source: 0001562180-24-004749 · primarydocument.xml · derivative · entry 2

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,229

Underlying: Ordinary Shares · 6,229 shares

Expires 2034-06-04

F2 · derivative.exercise_date: Options to buy 6,229 ordinary shares will fully vest and become exercisable on the earlier of the following dates: (i) the first anniversary of the grant date or (ii) the day immediately preceding the Company's 2025 annual general meeting of shareholders.

SEC source: 0001562180-24-004749 · primarydocument.xml · nonDerivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,590

F1 · shares: These restricted stock units are scheduled to vest 100% on the earlier of the following dates: (i) the first anniversary of the grant date or (ii) the day immediately preceding the Company's 2025 annual general meeting of shareholders.

SEC source: 0001209191-23-050826 · doc4.xml · derivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 12,500

Underlying: Common Stock · 12,500 shares

Expires 2033-09-26

F1 · security: This option is granted to non-employee directors in accordance with the Company's compensation program for non-employee directors, which provides that each non-employee director is eligible to receive an annual option grant to purchase 12,500 shares of common stock per year.

F2 · derivative.exercise_date: The shares subject to this option vest in four equal quarterly installments at a rate of 1/4 of the total number of shares every three months, with the first 1/4 vesting on the date that is three months following September 27, 2023 and an additional 1/4 every three months thereafter, subject in each case to the continued service of the Reporting Person as a non-employee director as of such vesting date.

SEC source: 0001562180-23-005383 · primarydocument.xml · nonDerivative · entry 2

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 15,349

F1 · kind: The sale reported on this Form 4 was effected pursuant to a 10b5-1 trading plan.

F2 · balance_after: Includes 4,866 shares issuable on the settlement of restricted stock units granted to the Reporting Person. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001562180-23-005383 · primarydocument.xml · nonDerivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 17,430

F1 · kind: The sale reported on this Form 4 was effected pursuant to a 10b5-1 trading plan.

SEC source: 0001562180-23-005110 · primarydocument.xml · nonDerivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 19,511

F1 · shares: Reflects shares issuable on the settlement of restricted stock units granted to the Reporting Person. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock. The shares subject to the restricted stock unit will vest 100% upon the earlier of (i) the next annual general meeting of the stockholders of the Company or (ii) the date one year from the Vesting Commencement Date, subject to the Reporting Person's continuous service as a member of the Company's Board of Directors until such date.

F2 · balance_after: Includes 4,866 shares issuable on the settlement of restricted stock units granted to the Reporting Person. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001562180-23-005012 · primarydocument.xml · derivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 12,554

Underlying: Ordinary Shares · 12,554 shares

Expires 2033-06-06

F1 · derivative.exercise_date: Options to buy 12,554 ordinary shares will fully vest and become exercisable on the earlier of the following dates: (i) the first anniversary of the grant date or (ii) the day immediately preceding the Company's 2024 annual general meeting of shareholders.

SEC source: 0000899243-23-015279 · doc4.xml · derivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 22,500

Underlying: Common Stock · 22,500 shares

Expires 2033-06-06

F1 · derivative.exercise_date: The option was granted pursuant to the Registrant's non-employee director compensation program. The option shall vest and/or become exercisable on the first to occur of (i) the first anniversary of the grant date or (ii) the next occurring annual meeting of our stockholders, in each case, subject to the non-employee director continuing in service on our board of directors through such vesting dates.

SEC source: 0000899243-22-029530 · doc4.xml · derivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,000

Underlying: Common Stock · 25,000 shares

Expires 2032-08-18

F1 · derivative.exercise_date: The options shall vest on the first anniversary of the date of grant, subject to reporting person's continuing in service on the registrant's board of directors through such vesting date.

SEC source: 0001562180-22-005231 · primarydocument.xml · nonDerivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,645

F1 · shares: Reflects shares issuable on the settlement of restricted stock units granted to the Reporting Person. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock. The shares subject to the restricted stock unit will vest 100% upon the earlier of (i) the next annual general meeting of the stockholders of the Company or (ii) the date one year from the Vesting Commencement Date, subject to the Reporting Person's continuous service as a member of the Company's Board of Directors until such date.

F2 · balance_after: Includes 8,324 shares issuable on the settlement of restricted stock units granted to the Reporting Person. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001562180-22-005093 · primarydocument.xml · nonDerivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,321

F1 · kind: The sale reported on this Form 4 was effected pursuant to a 10b5-1 trading plan.

F2 · price: The price reported in column 4 is a weighted-average price. The shares were sold in multiple transactions ranging from $13.8045 to $13.84, inclusive. The Reporting Person undertakes to provide the Issuer, any securityholder of the Issuer, or the Staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in these footnotes.

SEC source: 0001645113-22-000057 · wf-form4_165541090953677.xml · nonDerivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,537

F1 · shares: Transaction was made pursuant to a Rule 10b5-1 trading plan adopted by Ms. Hilleman.

SEC source: 0001209191-22-039689 · doc4.xml · derivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,500

Underlying: Common Stock · 2,500 shares

Expires 2032-06-09

F1 · security: This option is granted to non-employee directors in accordance with the Issuer's compensation program for non-employee directors, which provides that each non-employee director is eligible to receive an annual option grant to purchase 2,500 shares of common stock per year.

F2 · derivative.exercise_price: On June 17, 2022, the Issuer completed a 1-for-8 reverse stock split of the Issuer's common stock ("Reverse Stock Split"). This amount has been adjusted to give effect to the Reverse Stock Split.

F2 · shares: On June 17, 2022, the Issuer completed a 1-for-8 reverse stock split of the Issuer's common stock ("Reverse Stock Split"). This amount has been adjusted to give effect to the Reverse Stock Split.

F3 · derivative.exercise_date: The shares subject to this option vest in four equal quarterly installments at a rate of 1/4 of the total number of shares every three months, with the first 1/4 vesting on the date that is three months following June 10, 2022 and an additional 1/4 every three months thereafter, subject in each case to the continued service of the Reporting Person as a non-employee director as of such vesting date.

F2 · derivative.underlying_shares: On June 17, 2022, the Issuer completed a 1-for-8 reverse stock split of the Issuer's common stock ("Reverse Stock Split"). This amount has been adjusted to give effect to the Reverse Stock Split.

F2 · balance_after: On June 17, 2022, the Issuer completed a 1-for-8 reverse stock split of the Issuer's common stock ("Reverse Stock Split"). This amount has been adjusted to give effect to the Reverse Stock Split.

SEC source: 0001645113-22-000050 · wf-form4_165489168529039.xml · derivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,700

Underlying: Ordinary Shares · 8,700 shares

Expires 2032-06-08

F1 · derivative.exercise_date: Options to buy 8,700 ordinary shares will fully vest and become exercisable on the earlier of the following dates: (i) the first anniversary of the grant date or (ii) the day immediately preceding the Company's 2023 annual general meeting of shareholders.

SEC source: 0001562180-21-004532 · primarydocument.xml · nonDerivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,245

F1 · kind: The sale reported on this Form 4 was effected pursuant to a 10b5-1 trading plan.

F2 · balance_after: Includes 3,848 shares issuable on the settlement of restricted stock units granted to the Reporting Person. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001209191-21-040680 · doc4.xml · derivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,000

Underlying: Common Stock · 20,000 shares

Expires 2031-06-10

F1 · security: This option is granted to non-employee directors in accordance with the Company's compensation program for non-employee directors, which provides that each non-employee director is eligible to receive an annual option grant to purchase 20,000 shares of common stock per year.

F2 · derivative.exercise_date: The shares subject to this option vest in four equal quarterly installments at a rate of 1/4 of the total number of shares every three months, with the first 1/4 vesting on the date that is three months following June 11, 2021 and an additional 1/4 every three months thereafter, subject in each case to the continued service of the Reporting Person as a non-employee director as of such vesting date.

SEC source: 0001562180-21-004254 · primarydocument.xml · nonDerivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,645

F1 · shares: Reflects shares issuable on the settlement of restricted stock units granted to the Reporting Person. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock. The shares subject to the restricted stock unit will be vesting 100% upon the earlier of (i) the next annual general meeting of the stockholders of the Company or (ii) the date one year from the Vesting Commencement Date, subject to the Reporting Person's continuous service as a member of the Company's Board of Directors until such date.

F2 · balance_after: Includes 3,848 shares issuable on settlement of restricted stock units granted to the Reporting Person. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001645113-21-000076 · wf-form4_162344285531541.xml · derivative · entry 3

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,499

Underlying: Ordinary Shares · 1,499 shares

Expires 2031-06-09

F3 · derivative.exercise_date: Options to buy 1,499 ordinary shares will fully vest and become exercisable on the earlier of the following dates: (i) the first anniversary of the grant date or (ii) the day immediately preceding the Company's 2022 annual general meeting of shareholders.

SEC source: 0001645113-21-000076 · wf-form4_162344285531541.xml · nonDerivative · entry 2

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,944

F2 · shares: Transaction was made pursuant to a Rule 10b5-1 trading plan adopted by Ms. Hilleman.

SEC source: 0001645113-21-000076 · wf-form4_162344285531541.xml · nonDerivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,214

F1 · shares: These restricted stock units are scheduled to vest 100% on the earlier of the following dates: (1) the first anniversary of the grant date or (ii) the day immediately preceding the Company's 2022 annual general meeting of shareholders.

SEC source: 0001209191-21-021831 · doc4.xml · derivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 35,112

Underlying: Common Stock · 35,112 shares

Expires 2031-03-15

F1 · derivative.exercise_date: 1/36th of the shares subject to the option shall vest monthly over the three years from the grant date.

SEC source: 0001628280-20-017711 · wf-form4_160868029605808.xml · nonDerivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,400

F1 · shares: Transaction was made pursuant to a Rule 10b5-1 trading plan adopted by Ms. Hilleman.

SEC source: 0001562180-20-004588 · primarydocument.xml · nonDerivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,797

F1 · shares: Reflects shares issuable on the settlement of restricted stock units granted to the Reporting Person. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock. The shares subject to the restricted stock unit will be vesting 100% upon the earlier of (i) the next annual general meeting of the stockholders of the Company or (ii) the date one year from the Vesting Commencement Date, subject to the Reporting Person's continuous service as a member of the Company's Board of Directors until such date.

F2 · balance_after: Includes 8,797 shares issuable on the settlement of restricted stock units granted to the Reporting Person. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001209191-20-036336 · doc4.xml · derivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,000

Underlying: Common Stock · 20,000 shares

Expires 2030-06-10

F1 · security: This option is granted to non-employee directors in accordance with the Company's compensation program for non-employee directors, which provides that each non-employee director is eligible to receive an annual option grant to purchase 20,000 shares of common stock per year.

F2 · derivative.exercise_date: The shares subject to this option vest in four equal quarterly installments at a rate of 1/4 of the total number of shares every three months, with the first 1/4 vesting on the date that is three months following June 11, 2020 and an additional 1/4 every three months thereafter, subject in each case to the continued service of the Reporting Person as a non-employee director as of such vesting date.

SEC source: 0001645113-20-000090 · wf-form4_159199992057717.xml · derivative · entry 2

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,101

Underlying: Ordinary Shares · 5,101 shares

Expires 2030-06-10

F2 · derivative.exercise_date: Options to buy 5,101 ordinary shares will fully vest and become exercisable on the earlier of the following dates: (i) the first anniversary of the grant date or (ii) the day immediately preceding the Company's 2021 annual general meeting of shareholders.

SEC source: 0001645113-20-000090 · wf-form4_159199992057717.xml · nonDerivative · entry 1

HILLEMAN JERYL L · CIK 0001216628 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,900

F1 · shares: These restricted stock units are scheduled to vest 100% on the earlier of the following dates: (1) the first anniversary of the grant date or (ii) the day immediately preceding the Company's 2021 annual general meeting of shareholders.