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person · Reporting owner

Lewis William

Disclosed activity across 3 companies

Tapewire entity
28834
SEC CIK
0001402051

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Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
INSMED IncINSM · Entity 3174Director · Chair and CEOJuly 23, 2026July 24, 2026
NewAmsterdam Pharma Co N.V.NAMS · Entity 1826DirectorJanuary 07, 2026January 10, 2026
uniQure N.V.QURE · Entity 4162DirectorJanuary 27, 2017January 31, 2017

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

INSMED Inc

Report date July 23, 2026 · Filed July 24, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect259,058 Ending reported balance After 2026-07-23 transaction · row 4
4 source rows · reconciled sequence

Row 1 · 2026-07-23 · Exercise / conversion · Acquired 6,260 · Balance 265,318

F1: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Row 2 · 2026-07-23 · Exercise / conversion · Acquired 4,440 · Balance 269,758

F1: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Row 3 · 2026-07-23 · Sale · Disposed 4,828 · Balance 264,930

F1: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2: This is the weighted average sales price representing 4,828 shares sold at prices ranging from $105.09 to $106.02 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Row 4 · 2026-07-23 · Sale · Disposed 5,872 · Balance 259,058

F1: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3: This is the weighted average sales price representing 5,872 shares sold at prices ranging from $106.09 to $106.78 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Stock Option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $30.46 · Expires 2028-01-04Direct0 Reported balance After 2026-07-23 transaction · row 6 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 6 · 2026-07-23 · Exercise / conversion · Disposed 6,260 · Balance 0

F1: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Stock Option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $17.16 · Expires 2027-05-17Direct0 Reported balance After 2026-07-23 transaction · row 7 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 7 · 2026-07-23 · Exercise / conversion · Disposed 4,440 · Balance 0

F1: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Common StockSEC Table I · non-derivativeIndirectBy trust233,924 Reported balance Holding disclosure · report date 2026-07-23 · row 5 Holding and transaction disclosures are not merged.
1 source row

Row 5 · Balance 233,924

Filing footnotes · ownership attribution and instrument terms

F1: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2: This is the weighted average sales price representing 4,828 shares sold at prices ranging from $105.09 to $106.02 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

F3: This is the weighted average sales price representing 5,872 shares sold at prices ranging from $106.09 to $106.78 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

F4: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

NewAmsterdam Pharma Co N.V.

Report date January 07, 2026 · Filed January 10, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Ordinary SharesSEC Table I · non-derivativeDirect10,360 Reported balance After 2026-01-07 transaction · row 1
1 source row

Row 1 · 2026-01-07 · Grant · Acquired 3,400 · Balance 10,360

F1: Represents restricted stock units (RSUs), each representing a contingent right to receive one ordinary share. All of the RSUs will vest on the one-year anniversary of the vesting start date, subject to the Reporting Person's continued service through such date.

F2: Each RSU was granted on January 7, 2026 for no consideration.

Option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $35.45 · Expires 2036-01-07Direct15,300 Reported balance After 2026-01-07 transaction · row 2 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 2 · 2026-01-07 · Grant · Acquired 15,300 · Balance 15,300

F3: All of the ordinary shares underlying the option will vest on January 2, 2027, the one-year anniversary of the vesting start date, subject to the Reporting Person's continued service through such date.

Filing footnotes · ownership attribution and instrument terms

F1: Represents restricted stock units (RSUs), each representing a contingent right to receive one ordinary share. All of the RSUs will vest on the one-year anniversary of the vesting start date, subject to the Reporting Person's continued service through such date.

F2: Each RSU was granted on January 7, 2026 for no consideration.

F3: All of the ordinary shares underlying the option will vest on January 2, 2027, the one-year anniversary of the vesting start date, subject to the Reporting Person's continued service through such date.

uniQure N.V.

Report date January 27, 2017 · Filed January 31, 2017

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $5.37 · Expires 2027-01-27Direct11,000 Reported balance After 2017-01-27 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2017-01-27 · Grant · Acquired 11,000 · Balance 11,000

F1: The Stock Option vests 100% on January 27, 2018.

Restricted Stock UnitsSEC Table II · derivative / convertible security · Conversion / exercise price $0.00Direct16,000 Reported balance After 2017-01-27 transaction · row 2 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 2 · 2017-01-27 · Grant · Acquired 11,000 · Balance 16,000

F2: The Restricted Stock Unit vests 100% on January 27, 2018.

F3: Expiration date is not applicable as the vested Restricted Stock Units shall be settled on the first business day following the date that such Restricted Stock Units vests.

Filing footnotes · ownership attribution and instrument terms

F1: The Stock Option vests 100% on January 27, 2018.

F2: The Restricted Stock Unit vests 100% on January 27, 2018.

F3: Expiration date is not applicable as the vested Restricted Stock Units shall be settled on the first business day following the date that such Restricted Stock Units vests.

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
April 01, 2025 Filed Apr 3, 2025 20:25 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 3,021 $72.29 $218,388.09
Disclosure

SEC source: 0001628280-25-016508 · wk-form4_1743711913.xml · nonDerivative · entry 2

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · By the Katie Procter Dynasty Trust

Disclosed balance after: 237,733

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · price: This is the weighted average sales price representing 3,021 shares sold at prices ranging from $72.00 to $72.88 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
April 01, 2025 Filed Apr 3, 2025 20:25 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 6,830 $10.85 $74,105.50
Disclosure

SEC source: 0001628280-25-016508 · wk-form4_1743711913.xml · nonDerivative · entry 1

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · By the Katie Procter Dynasty Trust

Disclosed balance after: 240,754

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
March 17, 2025 Filed Mar 19, 2025 20:53 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 6,830 $0.00 Strike: $10.85 $0.00
Disclosure

SEC source: 0001628280-25-013864 · wk-form4_1742417573.xml · derivative · entry 11

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · By the Katie Procter Dynasty Trust

Disclosed balance after: 191,310

Underlying: Common Stock · 6,830 shares

Expires 2026-05-19

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F8 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant. All options are currently exercisable.

Read SEC document
March 17, 2025 Filed Mar 19, 2025 20:53 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 18,750 $0.00 Strike: $22.76 $0.00
Disclosure

SEC source: 0001628280-25-013864 · wk-form4_1742417573.xml · derivative · entry 10

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 18,750 shares

Expires 2025-05-21

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F8 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant. All options are currently exercisable.

Read SEC document
March 17, 2025 Filed Mar 19, 2025 20:53 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 2,737 $77.83 $213,020.71
Disclosure

SEC source: 0001628280-25-013864 · wk-form4_1742417573.xml · nonDerivative · entry 8

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · By the Katie Procter Dynasty Trust

Disclosed balance after: 233,924

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F7 · price: This is the weighted average sales price representing 2,737 shares sold at prices ranging from $77.72 to $77.99 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
March 17, 2025 Filed Mar 19, 2025 20:53 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 2,070 $77.01 $159,410.70
Disclosure

SEC source: 0001628280-25-013864 · wk-form4_1742417573.xml · nonDerivative · entry 7

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · By the Katie Procter Dynasty Trust

Disclosed balance after: 236,661

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F6 · price: This is the weighted average sales price representing 2,070 shares sold at prices ranging from $76.54 to $77.50 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
March 17, 2025 Filed Mar 19, 2025 20:53 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 2,023 $76.00 $153,748.00
Disclosure

SEC source: 0001628280-25-013864 · wk-form4_1742417573.xml · nonDerivative · entry 6

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · By the Katie Procter Dynasty Trust

Disclosed balance after: 238,731

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F5 · price: This is the weighted average sales price representing 2,023 shares sold at prices ranging from $75.52 to $76.47 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
March 17, 2025 Filed Mar 19, 2025 20:53 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 6,830 $10.85 $74,105.50
Disclosure

SEC source: 0001628280-25-013864 · wk-form4_1742417573.xml · nonDerivative · entry 5

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · By the Katie Procter Dynasty Trust

Disclosed balance after: 240,754

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
March 17, 2025 Filed Mar 19, 2025 20:53 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 8,116 $77.79 $631,343.64
Disclosure

SEC source: 0001628280-25-013864 · wk-form4_1742417573.xml · nonDerivative · entry 4

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 334,186

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4 · price: This is the weighted average sales price representing 8,116 shares sold at prices ranging from $77.34 to $78.06 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
March 17, 2025 Filed Mar 19, 2025 20:53 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 5,907 $76.87 $454,071.09
Disclosure

SEC source: 0001628280-25-013864 · wk-form4_1742417573.xml · nonDerivative · entry 3

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 342,302

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · price: This is the weighted average sales price representing 5,907 shares sold at prices ranging from $76.32 to $77.31 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
March 17, 2025 Filed Mar 19, 2025 20:53 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 4,727 $75.91 $358,826.57
Disclosure

SEC source: 0001628280-25-013864 · wk-form4_1742417573.xml · nonDerivative · entry 2

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 348,209

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · price: This is the weighted average sales price representing 4,727 shares sold at prices ranging from $75.32 to $76.31 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
March 17, 2025 Filed Mar 19, 2025 20:53 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 18,750 $22.76 $426,750.00
Disclosure

SEC source: 0001628280-25-013864 · wk-form4_1742417573.xml · nonDerivative · entry 1

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 352,936

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
March 03, 2025 Filed Mar 5, 2025 22:27 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 6,830 $0.00 Strike: $10.85 $0.00
Disclosure

SEC source: 0001628280-25-010590 · wk-form4_1741213663.xml · derivative · entry 15

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · By the Katie Procter Dynasty Trust

Disclosed balance after: 198,140

Underlying: Common Stock · 6,830 shares

Expires 2026-05-19

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F10 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant. All options are currently exercisable.

Read SEC document
March 03, 2025 Filed Mar 5, 2025 22:27 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 18,750 $0.00 Strike: $22.76 $0.00
Disclosure

SEC source: 0001628280-25-010590 · wk-form4_1741213663.xml · derivative · entry 14

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 18,750

Underlying: Common Stock · 18,750 shares

Expires 2025-05-21

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F10 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant. All options are currently exercisable.

Read SEC document
March 03, 2025 Filed Mar 5, 2025 22:27 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 46 $80.90 $3,721.40
Disclosure

SEC source: 0001628280-25-010590 · wk-form4_1741213663.xml · nonDerivative · entry 12

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · By the Katie Procter Dynasty Trust

Disclosed balance after: 233,924

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
March 03, 2025 Filed Mar 5, 2025 22:27 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 377 $79.73 $30,058.21
Disclosure

SEC source: 0001628280-25-010590 · wk-form4_1741213663.xml · nonDerivative · entry 11

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · By the Katie Procter Dynasty Trust

Disclosed balance after: 233,970

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F9 · price: This is the weighted average sales price representing 377 shares sold at prices ranging from $79.53 to $79.90 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
March 03, 2025 Filed Mar 5, 2025 22:27 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 2,250 $78.97 $177,682.50
Disclosure

SEC source: 0001628280-25-010590 · wk-form4_1741213663.xml · nonDerivative · entry 10

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · By the Katie Procter Dynasty Trust

Disclosed balance after: 234,347

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F8 · price: This is the weighted average sales price representing 2,250 shares sold at prices ranging from $78.49 to $79.42 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
March 03, 2025 Filed Mar 5, 2025 22:27 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 1,486 $78.20 $116,205.20
Disclosure

SEC source: 0001628280-25-010590 · wk-form4_1741213663.xml · nonDerivative · entry 9

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · By the Katie Procter Dynasty Trust

Disclosed balance after: 236,597

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F7 · price: This is the weighted average sales price representing 1,486 shares sold at prices ranging from $77.48 to $78.46 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
March 03, 2025 Filed Mar 5, 2025 22:27 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 2,671 $76.23 $203,610.33
Disclosure

SEC source: 0001628280-25-010590 · wk-form4_1741213663.xml · nonDerivative · entry 8

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · By the Katie Procter Dynasty Trust

Disclosed balance after: 238,083

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F6 · price: This is the weighted average sales price representing 2,671 shares sold at prices ranging from $75.93 to $76.77 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
March 03, 2025 Filed Mar 5, 2025 22:27 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 6,830 $10.85 $74,105.50
Disclosure

SEC source: 0001628280-25-010590 · wk-form4_1741213663.xml · nonDerivative · entry 7

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · By the Katie Procter Dynasty Trust

Disclosed balance after: 240,754

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
March 03, 2025 Filed Mar 5, 2025 22:27 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 127 $80.90 $10,274.30
Disclosure

SEC source: 0001628280-25-010590 · wk-form4_1741213663.xml · nonDerivative · entry 6

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 334,186

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
March 03, 2025 Filed Mar 5, 2025 22:27 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 2,785 $79.43 $221,212.55
Disclosure

SEC source: 0001628280-25-010590 · wk-form4_1741213663.xml · nonDerivative · entry 5

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 334,313

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F5 · price: This is the weighted average sales price representing 2,785 shares sold at prices ranging from $79.14 to $79.91 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
March 03, 2025 Filed Mar 5, 2025 22:27 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 7,763 $78.61 $610,249.43
Disclosure

SEC source: 0001628280-25-010590 · wk-form4_1741213663.xml · nonDerivative · entry 4

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 337,098

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4 · price: This is the weighted average sales price representing 7,763 shares sold at prices ranging from $78.13 to $79.11 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

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March 03, 2025 Filed Mar 5, 2025 22:27 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 758 $77.75 $58,934.50
Disclosure

SEC source: 0001628280-25-010590 · wk-form4_1741213663.xml · nonDerivative · entry 3

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 344,861

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · price: This is the weighted average sales price representing 758 shares sold at prices ranging from $77.13 to $78.12 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

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March 03, 2025 Filed Mar 5, 2025 22:27 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 7,317 $76.24 $557,848.08
Disclosure

SEC source: 0001628280-25-010590 · wk-form4_1741213663.xml · nonDerivative · entry 2

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 345,619

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · price: This is the weighted average sales price representing 7,317 shares sold at prices ranging from $75.91 to $76.90 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

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March 03, 2025 Filed Mar 5, 2025 22:27 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 18,750 $22.76 $426,750.00
Disclosure

SEC source: 0001628280-25-010590 · wk-form4_1741213663.xml · nonDerivative · entry 1

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 352,936

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

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February 18, 2025 Filed Feb 20, 2025 21:52 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 6,830 $0.00 Strike: $10.85 $0.00
Disclosure

SEC source: 0001628280-25-006807 · wk-form4_1740088354.xml · derivative · entry 11

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · By the Katie Procter Dynasty Trust

Disclosed balance after: 204,970

Underlying: Common Stock · 6,830 shares

Expires 2026-05-19

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F9 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant. All options are currently exercisable.

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February 18, 2025 Filed Feb 20, 2025 21:52 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 18,750 $0.00 Strike: $22.76 $0.00
Disclosure

SEC source: 0001628280-25-006807 · wk-form4_1740088354.xml · derivative · entry 10

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 37,500

Underlying: Common Stock · 18,750 shares

Expires 2025-05-21

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F9 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant. All options are currently exercisable.

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February 18, 2025 Filed Feb 20, 2025 21:52 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 300 $81.81 $24,543.00
Disclosure

SEC source: 0001628280-25-006807 · wk-form4_1740088354.xml · nonDerivative · entry 8

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · By the Katie Procter Dynasty Trust

Disclosed balance after: 233,924

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F8 · price: This is the weighted average sales price representing 300 shares sold at prices ranging from $81.69 to $82.01 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

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February 18, 2025 Filed Feb 20, 2025 21:52 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 6,074 $81.07 $492,419.18
Disclosure

SEC source: 0001628280-25-006807 · wk-form4_1740088354.xml · nonDerivative · entry 7

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · By the Katie Procter Dynasty Trust

Disclosed balance after: 234,224

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F7 · price: This is the weighted average sales price representing 6,074 shares sold at prices ranging from $80.51 to $81.42 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
February 18, 2025 Filed Feb 20, 2025 21:52 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 456 $80.00 $36,480.00
Disclosure

SEC source: 0001628280-25-006807 · wk-form4_1740088354.xml · nonDerivative · entry 6

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · By the Katie Procter Dynasty Trust

Disclosed balance after: 240,298

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F6 · price: This is the weighted average sales price representing 456 shares sold at prices ranging from $79.50 to $80.34 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

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February 18, 2025 Filed Feb 20, 2025 21:52 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 6,830 $10.85 $74,105.50
Disclosure

SEC source: 0001628280-25-006807 · wk-form4_1740088354.xml · nonDerivative · entry 5

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · By the Katie Procter Dynasty Trust

Disclosed balance after: 240,754

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
February 18, 2025 Filed Feb 20, 2025 21:52 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 754 $81.67 $61,579.18
Disclosure

SEC source: 0001628280-25-006807 · wk-form4_1740088354.xml · nonDerivative · entry 4

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 334,186

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F5 · price: This is the weighted average sales price representing 754 shares sold at prices ranging from $81.56 to $81.78 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
February 18, 2025 Filed Feb 20, 2025 21:52 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 16,743 $81.08 $1,357,522.44
Disclosure

SEC source: 0001628280-25-006807 · wk-form4_1740088354.xml · nonDerivative · entry 3

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 334,940

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4 · price: This is the weighted average sales price representing 16,743 shares sold at prices ranging from $80.50 to $81.43 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
February 18, 2025 Filed Feb 20, 2025 21:52 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 1,253 $79.95 $100,177.35
Disclosure

SEC source: 0001628280-25-006807 · wk-form4_1740088354.xml · nonDerivative · entry 2

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 351,683

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · price: This is the weighted average sales price representing 1,253 shares sold at prices ranging from $79.50 to $80.35 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
February 18, 2025 Filed Feb 20, 2025 21:52 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 18,750 $22.76 $426,750.00
Disclosure

SEC source: 0001628280-25-006807 · wk-form4_1740088354.xml · nonDerivative · entry 1

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 352,936

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · balance_after: Since the date of the last ownership report for the Reporting Person, he transferred 92,155 shares of Company common stock, employee stock options to purchase 1,064,717 shares of Company common stock, and restricted stock units covering 27,553 shares of Company common stock to his ex-spouse pursuant to a mutually agreed divorce settlement approved by a court that qualifies as a domestic relations order. A domestic relations order is a court order that dictates how assets should be divided between spouses during a divorce, including securities in the Company. The Reporting Person no longer reports as beneficially owned any securities owned by his ex-spouse.

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February 06, 2025 Filed Feb 7, 2025 22:11 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 79,350 $80.90 $6,419,415.00
Disclosure

SEC source: 0001628280-25-004461 · wk-form4_1738966272.xml · nonDerivative · entry 2

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 453,894

F2 · shares: Shares sold to satisfy tax withholding obligations upon the vesting of PSUs and to cover related broker fees.

F3 · price: This is the weighted average sales price representing 79,350 shares sold at prices ranging from $80.57 to $81.43 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
February 05, 2025 Filed Feb 7, 2025 22:11 UTC INSMED Inc INSM · Entity 3174 GrantCommon Stock 153,710 $0.00 $0.00
Disclosure

SEC source: 0001628280-25-004461 · wk-form4_1738966272.xml · nonDerivative · entry 1

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 533,244

F1 · shares: Represents shares of common stock acquired upon vesting of Performance Stock Units (PSUs) that were originally granted on January 6, 2022, which vested on February 5, 2025 upon the achievement of the applicable performance and service conditions.

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February 03, 2025 Filed Feb 5, 2025 21:44 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 6,830 $0.00 Strike: $10.85 $0.00
Disclosure

SEC source: 0001628280-25-004076 · wk-form4_1738791860.xml · derivative · entry 13

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · By the Katie Procter Dynasty Trust

Disclosed balance after: 211,800

Underlying: Common Stock · 6,830 shares

Expires 2026-05-19

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F9 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant. All options are currently exercisable.

Read SEC document
February 03, 2025 Filed Feb 5, 2025 21:44 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 18,750 $0.00 Strike: $22.76 $0.00
Disclosure

SEC source: 0001628280-25-004076 · wk-form4_1738791860.xml · derivative · entry 12

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 56,250

Underlying: Common Stock · 18,750 shares

Expires 2025-05-21

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F9 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant. All options are currently exercisable.

Read SEC document
February 03, 2025 Filed Feb 5, 2025 21:44 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 2,581 $78.40 $202,350.40
Disclosure

SEC source: 0001628280-25-004076 · wk-form4_1738791860.xml · nonDerivative · entry 10

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · By the Katie Procter Dynasty Trust

Disclosed balance after: 233,924

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F8 · price: This is the weighted average sales price representing 2,581 shares sold at prices ranging from $78.26 to $78.75 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
February 03, 2025 Filed Feb 5, 2025 21:44 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 3,463 $77.95 $269,940.85
Disclosure

SEC source: 0001628280-25-004076 · wk-form4_1738791860.xml · nonDerivative · entry 9

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · By the Katie Procter Dynasty Trust

Disclosed balance after: 236,505

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F7 · price: This is the weighted average sales price representing 3,463 shares sold at prices ranging from $77.24 to $78.23 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
February 03, 2025 Filed Feb 5, 2025 21:44 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 745 $76.43 $56,940.35
Disclosure

SEC source: 0001628280-25-004076 · wk-form4_1738791860.xml · nonDerivative · entry 8

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · By the Katie Procter Dynasty Trust

Disclosed balance after: 239,968

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F6 · price: This is the weighted average sales price representing 745 shares sold at prices ranging from $76.10 to $76.90 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

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February 03, 2025 Filed Feb 5, 2025 21:44 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 41 $74.86 $3,069.26
Disclosure

SEC source: 0001628280-25-004076 · wk-form4_1738791860.xml · nonDerivative · entry 7

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · By the Katie Procter Dynasty Trust

Disclosed balance after: 240,713

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
February 03, 2025 Filed Feb 5, 2025 21:44 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 6,830 $10.85 $74,105.50
Disclosure

SEC source: 0001628280-25-004076 · wk-form4_1738791860.xml · nonDerivative · entry 6

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · By the Katie Procter Dynasty Trust

Disclosed balance after: 240,754

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
February 03, 2025 Filed Feb 5, 2025 21:44 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 6,768 $78.44 $530,881.92
Disclosure

SEC source: 0001628280-25-004076 · wk-form4_1738791860.xml · nonDerivative · entry 5

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 379,534

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F5 · price: This is the weighted average sales price representing 6,768 shares sold at prices ranging from $78.31 to $78.80 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
February 03, 2025 Filed Feb 5, 2025 21:44 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 9,869 $77.97 $769,485.93
Disclosure

SEC source: 0001628280-25-004076 · wk-form4_1738791860.xml · nonDerivative · entry 4

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 386,302

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4 · price: This is the weighted average sales price representing 9,869 shares sold at prices ranging from $77.29 to $78.28 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
February 03, 2025 Filed Feb 5, 2025 21:44 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 1,872 $76.35 $142,927.20
Disclosure

SEC source: 0001628280-25-004076 · wk-form4_1738791860.xml · nonDerivative · entry 3

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 396,171

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · price: This is the weighted average sales price representing 1,872 shares sold at prices ranging from $76.00 to $76.57 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
February 03, 2025 Filed Feb 5, 2025 21:44 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 241 $75.25 $18,135.25
Disclosure

SEC source: 0001628280-25-004076 · wk-form4_1738791860.xml · nonDerivative · entry 2

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 398,043

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · price: This is the weighted average sales price representing 241 shares sold at prices ranging from $74.86 to $75.83 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
February 03, 2025 Filed Feb 5, 2025 21:44 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 18,750 $22.76 $426,750.00
Disclosure

SEC source: 0001628280-25-004076 · wk-form4_1738791860.xml · nonDerivative · entry 1

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 398,284

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.