Santos David A

SEC source: 0000905148-26-004079 · form4.xml · nonDerivative · entry 1

Santos David A · CIK 0001820066 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 61,622

F1 · balance_after: Includes 500 shares acquired under the Issuer's stock purchase plan.

SEC source: 0000905148-26-003037 · form4.xml · derivative · entry 1

Santos David A · CIK 0001820066 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,394

Underlying: Common Stock · 7,394 shares

Expires 2035-01-29

F1 · derivative.exercise_price: The Reporting Person was granted a stock option with a performance-based condition with respect to 7,394 shares of the Issuer's common stock on January 29, 2025. The exercise price of this option is $22.49, which is the closing price of the Issuer's common stock on Nasdaq on the date of grant. In light of the performance-based vesting condition, this grant was not reportable under Section 16 until the performance metric was satisfied. On June 17, 2026, it was determined that the performance metric had been met.

F1 · shares: The Reporting Person was granted a stock option with a performance-based condition with respect to 7,394 shares of the Issuer's common stock on January 29, 2025. The exercise price of this option is $22.49, which is the closing price of the Issuer's common stock on Nasdaq on the date of grant. In light of the performance-based vesting condition, this grant was not reportable under Section 16 until the performance metric was satisfied. On June 17, 2026, it was determined that the performance metric had been met.

F2 · derivative.exercise_date: The option was fully vested on June 17, 2026, the date the determination was made that the performance metric had been met.

F1 · derivative.underlying_shares: The Reporting Person was granted a stock option with a performance-based condition with respect to 7,394 shares of the Issuer's common stock on January 29, 2025. The exercise price of this option is $22.49, which is the closing price of the Issuer's common stock on Nasdaq on the date of grant. In light of the performance-based vesting condition, this grant was not reportable under Section 16 until the performance metric was satisfied. On June 17, 2026, it was determined that the performance metric had been met.

SEC source: 0000905148-26-002810 · form4.xml · nonDerivative · entry 1

Santos David A · CIK 0001820066 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 61,996

SEC source: 0000905148-26-000954 · form4.xml · nonDerivative · entry 1

Santos David A · CIK 0001820066 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 62,870

F1 · shares: The shares of common stock are to be acquired upon the vesting of a Restricted Stock Unit award granted to the Reporting Person. The Restricted Stock Units shall vest quarterly over three (3) years, with the first quarterly vest occurring on March 31, 2026.

SEC source: 0000905148-26-000679 · form4.xml · nonDerivative · entry 1

Santos David A · CIK 0001820066 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 43,440

SEC source: 0000905148-26-000498 · form4.xml · nonDerivative · entry 1

Santos David A · CIK 0001820066 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 46,986

F1 · balance_after: Includes 1,000 shares acquired under the Issuer's stock purchase plan.

SEC source: 0000905148-25-003350 · form4.xml · derivative · entry 1

Santos David A · CIK 0001820066 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,394

Underlying: Common Stock · 7,394 shares

Expires 2035-01-29

F1 · derivative.exercise_price: The Reporting Person was granted a stock option with a performance-based condition with respect to 7,394 shares of the Issuer's common stock on January 29, 2025. The exercise price of this option is $22.49, which is the closing price of the Issuer's common stock on Nasdaq on the date of grant. In light of the performance-based vesting condition, this grant was not reportable under Section 16 until the performance metric was satisfied. On September 15, 2025, it was determined that the performance metric had been met.

F1 · shares: The Reporting Person was granted a stock option with a performance-based condition with respect to 7,394 shares of the Issuer's common stock on January 29, 2025. The exercise price of this option is $22.49, which is the closing price of the Issuer's common stock on Nasdaq on the date of grant. In light of the performance-based vesting condition, this grant was not reportable under Section 16 until the performance metric was satisfied. On September 15, 2025, it was determined that the performance metric had been met.

F2 · derivative.exercise_date: The option was fully vested on September 15, 2025, the date the determination was made that the performance metric had been met.

F1 · derivative.underlying_shares: The Reporting Person was granted a stock option with a performance-based condition with respect to 7,394 shares of the Issuer's common stock on January 29, 2025. The exercise price of this option is $22.49, which is the closing price of the Issuer's common stock on Nasdaq on the date of grant. In light of the performance-based vesting condition, this grant was not reportable under Section 16 until the performance metric was satisfied. On September 15, 2025, it was determined that the performance metric had been met.

SEC source: 0000905148-25-000979 · form4.xml · derivative · entry 2

Santos David A · CIK 0001820066 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,850

Underlying: Common Stock · 7,850 shares

Expires 2034-01-23

F3 · derivative.exercise_price: The Reporting Person was granted a stock option with a performance-based condition with respect to 7,850 shares of the Issuer's common stock on January 23, 2024, as adjusted for the Reverse Stock Split. The exercise price of this option is $12.70, which is the closing price of the Issuer's common stock on Nasdaq on the date of grant, as adjusted for the Reverse Stock Split. In light of the performance-based vesting condition, this grant was not reportable under Section 16 until the performance metric was satisfied. On March 17, 2025, it was determined that the performance metric had been met.

F3 · shares: The Reporting Person was granted a stock option with a performance-based condition with respect to 7,850 shares of the Issuer's common stock on January 23, 2024, as adjusted for the Reverse Stock Split. The exercise price of this option is $12.70, which is the closing price of the Issuer's common stock on Nasdaq on the date of grant, as adjusted for the Reverse Stock Split. In light of the performance-based vesting condition, this grant was not reportable under Section 16 until the performance metric was satisfied. On March 17, 2025, it was determined that the performance metric had been met.

F2 · derivative.exercise_date: The option was fully vested on March 17, 2025, the date the determination was made that the performance metric had been met.

F3 · derivative.underlying_shares: The Reporting Person was granted a stock option with a performance-based condition with respect to 7,850 shares of the Issuer's common stock on January 23, 2024, as adjusted for the Reverse Stock Split. The exercise price of this option is $12.70, which is the closing price of the Issuer's common stock on Nasdaq on the date of grant, as adjusted for the Reverse Stock Split. In light of the performance-based vesting condition, this grant was not reportable under Section 16 until the performance metric was satisfied. On March 17, 2025, it was determined that the performance metric had been met.

SEC source: 0000905148-25-000979 · form4.xml · derivative · entry 1

Santos David A · CIK 0001820066 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,875

Underlying: Common Stock · 6,875 shares

Expires 2031-01-27

F1 · derivative.exercise_price: The Reporting Person was granted a stock option with a performance-based condition with respect to 6,875 shares of the Issuer's common stock on January 27, 2021, as adjusted for the one-for-ten reverse stock split effective June 27, 2024 (the "Reverse Stock Split"). The exercise price of this option is $35.40, which is the closing price of the Issuer's common stock on Nasdaq on the date of grant, as adjusted for the Reverse Stock Split. In light of the performance-based vesting condition, this grant was not reportable under Section 16 until the performance metric was satisfied. On March 17, 2025, it was determined that the performance metric had been met.

F1 · shares: The Reporting Person was granted a stock option with a performance-based condition with respect to 6,875 shares of the Issuer's common stock on January 27, 2021, as adjusted for the one-for-ten reverse stock split effective June 27, 2024 (the "Reverse Stock Split"). The exercise price of this option is $35.40, which is the closing price of the Issuer's common stock on Nasdaq on the date of grant, as adjusted for the Reverse Stock Split. In light of the performance-based vesting condition, this grant was not reportable under Section 16 until the performance metric was satisfied. On March 17, 2025, it was determined that the performance metric had been met.

F2 · derivative.exercise_date: The option was fully vested on March 17, 2025, the date the determination was made that the performance metric had been met.

F1 · derivative.underlying_shares: The Reporting Person was granted a stock option with a performance-based condition with respect to 6,875 shares of the Issuer's common stock on January 27, 2021, as adjusted for the one-for-ten reverse stock split effective June 27, 2024 (the "Reverse Stock Split"). The exercise price of this option is $35.40, which is the closing price of the Issuer's common stock on Nasdaq on the date of grant, as adjusted for the Reverse Stock Split. In light of the performance-based vesting condition, this grant was not reportable under Section 16 until the performance metric was satisfied. On March 17, 2025, it was determined that the performance metric had been met.

SEC source: 0000905148-25-000412 · form4.xml · nonDerivative · entry 2

Santos David A · CIK 0001820066 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 51,704

F1 · kind: These shares were sold to cover tax withholding due upon vesting of Restricted Stock Units. Such "sales to cover" were automatically effected to satisfy tax withholding obligations and do not represent a discretionary trade by the Reporting Person.

SEC source: 0000905148-25-000412 · form4.xml · nonDerivative · entry 1

Santos David A · CIK 0001820066 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 53,500

F1 · kind: These shares were sold to cover tax withholding due upon vesting of Restricted Stock Units. Such "sales to cover" were automatically effected to satisfy tax withholding obligations and do not represent a discretionary trade by the Reporting Person.

SEC source: 0000905148-25-000299 · form4.xml · derivative · entry 2

Santos David A · CIK 0001820066 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,788

Underlying: Common Stock · 14,788 shares

Expires 2035-01-29

F4 · derivative.exercise_date: The shares of common stock subject to the option vest monthly over three (3) years from the vesting commencement date of January 29, 2025, subject to the Reporting Person's continuous service to the Issuer through each such period.

SEC source: 0000905148-25-000299 · form4.xml · nonDerivative · entry 1

Santos David A · CIK 0001820066 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 55,625

F1 · shares: The shares of common stock are to be acquired upon the vesting of a Restricted Stock Unit award granted to the Reporting Person. The Restricted Stock Units shall vest annually over three (3) years from February 10, 2025, with the first annual vest occurring on February 10, 2026.

F2 · balance_after: This number has been adjusted to reflect the one-for-ten reverse stock split effective June 27, 2024.

F3 · balance_after: Includes 999 shares acquired under the Issuer's stock purchase plan.

SEC source: 0000905148-24-003283 · form4.xml · derivative · entry 1

Santos David A · CIK 0001820066 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,000

Underlying: Common Stock · 8,000 shares

Expires 2033-01-26

F1 · derivative.exercise_price: The Reporting Person was granted a stock option with a performance-based condition with respect to 8,000 shares of the Issuer's common stock on January 26, 2023, as adjusted for the one-for-ten reverse stock split effective June 27, 2024 (the "Reverse Stock Split"). The exercise price of this option is $18.70, which is the closing price of the Issuer's common stock on Nasdaq on the date of grant, as adjusted for the Reverse Stock Split. In light of the performance-based vesting condition, this grant was not reportable under Section 16 until the performance metric was satisfied. On November 25, 2024, it was determined that the performance metric had been met.

F1 · shares: The Reporting Person was granted a stock option with a performance-based condition with respect to 8,000 shares of the Issuer's common stock on January 26, 2023, as adjusted for the one-for-ten reverse stock split effective June 27, 2024 (the "Reverse Stock Split"). The exercise price of this option is $18.70, which is the closing price of the Issuer's common stock on Nasdaq on the date of grant, as adjusted for the Reverse Stock Split. In light of the performance-based vesting condition, this grant was not reportable under Section 16 until the performance metric was satisfied. On November 25, 2024, it was determined that the performance metric had been met.

F2 · derivative.exercise_date: The option was fully vested on November 25, 2024, the date the determination was made that the performance metric had been met.

F1 · derivative.underlying_shares: The Reporting Person was granted a stock option with a performance-based condition with respect to 8,000 shares of the Issuer's common stock on January 26, 2023, as adjusted for the one-for-ten reverse stock split effective June 27, 2024 (the "Reverse Stock Split"). The exercise price of this option is $18.70, which is the closing price of the Issuer's common stock on Nasdaq on the date of grant, as adjusted for the Reverse Stock Split. In light of the performance-based vesting condition, this grant was not reportable under Section 16 until the performance metric was satisfied. On November 25, 2024, it was determined that the performance metric had been met.

SEC source: 0000905148-24-000850 · form4.xml · derivative · entry 2

Santos David A · CIK 0001820066 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 78,500

Underlying: Common Stock · 78,500 shares

Expires 2034-01-23

F2 · shares: The Reporting Person was granted an option with a performance-based condition with respect to 78,500 shares of the issuer's common stock on January 23, 2024. Thus, the exercise price of this option is $1.27 (the closing price of the issuer's common stock on Nasdaq the date of grant). In light of the performance-based vesting condition of this grant, the grant was not reportable under Section 16 until the performance metric was satisfied. On February 28, 2024, it was determined that the performance metric had been met.

F3 · derivative.exercise_date: The option was fully vested on February 28, 2024, the date the determination was made that the performance metric had been met.

SEC source: 0000905148-24-000850 · form4.xml · derivative · entry 1

Santos David A · CIK 0001820066 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 80,000

Underlying: Common Stock · 80,000 shares

Expires 2033-01-26

F1 · shares: The Reporting Person was granted an option with a performance-based condition with respect to 80,000 shares of the issuer's common stock on January 26, 2023. Thus, the exercise price of this option is $1.87 (the closing price of the issuer's common stock on Nasdaq the date of grant). In light of the performance-based vesting condition of this grant, the grant was not reportable under Section 16 until the performance metric was satisfied. On February 28, 2024, it was determined that the performance metric had been met.

F3 · derivative.exercise_date: The option was fully vested on February 28, 2024, the date the determination was made that the performance metric had been met.

SEC source: 0000905148-24-000447 · form4.xml · nonDerivative · entry 2

Santos David A · CIK 0001820066 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 349,093

F1 · kind: These shares were sold to cover tax withholding due upon vesting of Restricted Stock Units. Such "sales to cover" were automatically effected to satisfy tax withholding obligations and do not represent a discretionary trade by the Reporting Person.

SEC source: 0000905148-24-000447 · form4.xml · nonDerivative · entry 1

Santos David A · CIK 0001820066 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 358,011

F1 · kind: These shares were sold to cover tax withholding due upon vesting of Restricted Stock Units. Such "sales to cover" were automatically effected to satisfy tax withholding obligations and do not represent a discretionary trade by the Reporting Person.

SEC source: 0000905148-24-000307 · form4.xml · derivative · entry 2

Santos David A · CIK 0001820066 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 157,000

Underlying: Common Stock · 157,000 shares

Expires 2034-01-23

F3 · derivative.exercise_date: The shares of common stock subject to the option vest monthly over three (3) years from the vesting commencement date of January 23, 2024, subject to the Reporting Person's continuous service to the issuer through each such period.

SEC source: 0000905148-24-000307 · form4.xml · nonDerivative · entry 1

Santos David A · CIK 0001820066 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 363,612

F1 · shares: The shares of common stock are to be acquired upon the vesting of a Restricted Stock Unit award granted to the Reporting Person. The Restricted Stock Units shall vest annually over three (3) years from February 1, 2024, with the first annual vest occurring on February 1, 2025.

F2 · balance_after: Includes 10,000 shares acquired under the Issuer's stock purchase plan.

SEC source: 0001140361-23-004733 · form4.xml · nonDerivative · entry 1

Santos David A · CIK 0001820066 · EVP, Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 144,612

F1 · kind: These shares were sold to cover tax withholding due upon vesting of Restricted Stock Units. Such "sales to cover" were automatically effected to satisfy tax withholding obligations and do not represent a discretionary trade by the Reporting Person.

SEC source: 0001140361-23-003439 · form4.xml · derivative · entry 3

Santos David A · CIK 0001820066 · EVP, Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 160,000

Underlying: Common Stock · 160,000 shares

Expires 2033-01-26

F5 · derivative.exercise_date: The shares of common stock subject to the option vest monthly over four (4) years from the vesting commencement date of January 1, 2023, subject to the Reporting Person's continuous service to the issuer through each such period.

SEC source: 0001140361-23-003439 · form4.xml · derivative · entry 2

Santos David A · CIK 0001820066 · EVP, Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 100,000

Underlying: Common Stock · 50,000 shares

Expires 2032-01-24

F3 · shares: The Reporting Person was granted an option with a performance-based condition with respect to 50,000 shares of common stock on January 24, 2022. Thus, the exercise price of this option is $2.42 (the closing price of the issuer's common stock on Nasdaq the date of grant). In light of the performance-based vesting condition of this grant, the grant was not reportable under Section 16 until the performance metric was satisfied. On January 26, 2023, it was determined that the performance metric had been met.

F4 · derivative.exercise_date: The option was fully vested on January 26, 2023, the date the determination was made that the performance metric had been met.

SEC source: 0001140361-23-003439 · form4.xml · nonDerivative · entry 1

Santos David A · CIK 0001820066 · EVP, Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 150,000

F1 · shares: The shares of common stock are to be acquired upon the vesting of a Restricted Stock Unit award granted to the Reporting Person. The Restricted Stock Units shall vest annually over four (4) years from February 1, 2023, with the first annual vest occurring on February 1, 2024.

F2 · balance_after: Includes 10,000 shares acquired under the issuer's stock purchase plan.

SEC source: 0001140361-22-047667 · form4.xml · derivative · entry 1

Santos David A · CIK 0001820066 · EVP, Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 50,000

Underlying: Common Stock · 50,000 shares

Expires 2032-01-24

F1 · shares: The Reporting Person was granted an option with a performance-based condition with respect to 50,000 shares of common stock on January 24, 2022. Thus, the exercise price of this option is $2.42 (the closing price of the issuer's common stock on Nasdaq the date of grant). In light of the performance-based vesting condition of this grant, the grant was not reportable under Section 16 until the performance metric was satisfied. On December 28, 2022, it was determined that the performance metric had been met.

F2 · derivative.exercise_date: The option was fully vested on December 28, 2022, the date the determination was made that the performance metric had been met.

SEC source: 0001567619-22-001780 · doc1.xml · derivative · entry 2

Santos David A · CIK 0001820066 · EVP, Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 100,000

Underlying: Common Stock · 100,000 shares

Expires 2032-01-24

F3 · derivative.exercise_date: The shares of common stock subject to the option vest monthly over four (4) years from the vesting commencement date of January 1, 2022, subject to the reporting person's continuous service to the issuer through each such period.

SEC source: 0001567619-22-001780 · doc1.xml · nonDerivative · entry 1

Santos David A · CIK 0001820066 · EVP, Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 60,000

F1 · shares: The shares of Common Stock are to be acquired upon the vesting of a Restricted Stock Unit award granted to the Reporting Person. The Restricted Stock Units shall vest annually over four (4) years from February 1, 2022, with the first annual vest occurring on February 1, 2023.

F2 · balance_after: Includes 10,000 shares acquired under the Issuer's stock purchase plan.

SEC source: 0001179110-21-000985 · edgar.xml · derivative · entry 1

Santos David A · CIK 0001820066 · EVP, Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 137,500

Underlying: Common Stock · 137,500 shares

Expires 2031-01-27

F1 · derivative.exercise_date: The shares of common stock subject to the option vest in equal monthly installments over four (4) years from the vesting commencement date of January 1, 2021, subject to the reporting person's continuous service to the issuer through each such period.

SEC source: 0001179110-20-009207 · edgar.xml · derivative · entry 1

Santos David A · CIK 0001820066 · EVP, Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 250,000

Underlying: Common Stock · 250,000 shares

Expires 2030-08-19

F1 · derivative.exercise_date: One fourth (1/4th) of the option vests one year from August 19, 2020 and thereafter the balance of the option vests in equal monthly installments over the next thirty-six (36) months.