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person · Reporting owner

OYLER JOHN

Disclosed activity across 1 company

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24276
SEC CIK
0001042047

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Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
BeOne Medicines Ltd.ONC · Entity 2168Director · Chief Executive OfficerAugust 10, 2026August 12, 2026

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

BeOne Medicines Ltd.

Report date August 10, 2026 · Filed August 12, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
American Depositary SharesSEC Table I · non-derivativeDirect0 Last balance in matching sequence After 2026-08-12 transaction · row 30 Source-order balances reconcile. Account continuity and personal attribution are not independently verified.
24 source rows

Row 7 · 2026-08-10 · Sale · Disposed 67 · Balance 240,743

F6: Each American Depositary Share represents 13 Ordinary Shares.

F7: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

Row 8 · 2026-08-10 · Sale · Disposed 2,813 · Balance 237,930

F6: Each American Depositary Share represents 13 Ordinary Shares.

F7: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F8: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $351.01 to $351.99, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Row 9 · 2026-08-10 · Sale · Disposed 3,673 · Balance 234,257

F6: Each American Depositary Share represents 13 Ordinary Shares.

F7: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F9: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $353.00 to $353.99, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Row 10 · 2026-08-10 · Sale · Disposed 6,717 · Balance 227,540

F6: Each American Depositary Share represents 13 Ordinary Shares.

F7: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F10: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $354.03 to $355.01, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Row 11 · 2026-08-10 · Sale · Disposed 3,476 · Balance 224,064

F6: Each American Depositary Share represents 13 Ordinary Shares.

F7: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F11: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $355.08 to $356.05, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Row 12 · 2026-08-10 · Sale · Disposed 12,418 · Balance 211,646

F6: Each American Depositary Share represents 13 Ordinary Shares.

F7: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F12: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $356.08 to $357.06, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Row 13 · 2026-08-10 · Sale · Disposed 15,869 · Balance 195,777

F6: Each American Depositary Share represents 13 Ordinary Shares.

F7: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F13: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $357.08 to $358.07, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Row 14 · 2026-08-10 · Sale · Disposed 45,044 · Balance 150,733

F6: Each American Depositary Share represents 13 Ordinary Shares.

F7: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F14: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $358.08 to $359.07, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Row 15 · 2026-08-10 · Sale · Disposed 21,254 · Balance 129,479

F6: Each American Depositary Share represents 13 Ordinary Shares.

F7: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F15: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $359.08 to $360.00, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Row 16 · 2026-08-10 · Sale · Disposed 3,680 · Balance 125,799

F6: Each American Depositary Share represents 13 Ordinary Shares.

F7: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F16: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $360.25 to $361.14, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Row 17 · 2026-08-11 · Sale · Disposed 13,695 · Balance 112,104

F6: Each American Depositary Share represents 13 Ordinary Shares.

F7: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F17: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $358.90 to $359.89, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Row 18 · 2026-08-11 · Sale · Disposed 8,081 · Balance 104,023

F6: Each American Depositary Share represents 13 Ordinary Shares.

F7: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F18: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $359.92 to $360.91, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Row 19 · 2026-08-11 · Sale · Disposed 14,569 · Balance 89,454

F6: Each American Depositary Share represents 13 Ordinary Shares.

F7: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F19: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $360.92 to $361.91, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Row 20 · 2026-08-11 · Sale · Disposed 11,568 · Balance 77,886

F6: Each American Depositary Share represents 13 Ordinary Shares.

F7: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F20: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $361.94 to $362.74, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Row 21 · 2026-08-11 · Sale · Disposed 13,403 · Balance 64,483

F6: Each American Depositary Share represents 13 Ordinary Shares.

F7: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F21: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $362.95 to $363.94, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Row 22 · 2026-08-11 · Sale · Disposed 5,211 · Balance 59,272

F6: Each American Depositary Share represents 13 Ordinary Shares.

F7: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F22: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $363.95 to $364.90, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Row 23 · 2026-08-11 · Sale · Disposed 3,176 · Balance 56,096

F6: Each American Depositary Share represents 13 Ordinary Shares.

F7: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F23: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $365.00 to $365.90, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Row 24 · 2026-08-11 · Sale · Disposed 1,200 · Balance 54,896

F6: Each American Depositary Share represents 13 Ordinary Shares.

F7: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F24: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $366.00 to $366.99, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Row 25 · 2026-08-11 · Sale · Disposed 4 · Balance 54,892

F6: Each American Depositary Share represents 13 Ordinary Shares.

F7: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

Row 26 · 2026-08-12 · Sale · Disposed 1,980 · Balance 52,912

F6: Each American Depositary Share represents 13 Ordinary Shares.

F7: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F25: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $354.35 to $355.05, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Row 27 · 2026-08-12 · Sale · Disposed 2,515 · Balance 50,397

F6: Each American Depositary Share represents 13 Ordinary Shares.

F7: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F26: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $355.92 to $356.91, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Row 28 · 2026-08-12 · Sale · Disposed 15,396 · Balance 35,001

F6: Each American Depositary Share represents 13 Ordinary Shares.

F7: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F27: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $356.95 to $357.94, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Row 29 · 2026-08-12 · Sale · Disposed 20,899 · Balance 14,102

F6: Each American Depositary Share represents 13 Ordinary Shares.

F7: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F28: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $357.95 to $358.94, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Row 30 · 2026-08-12 · Sale · Disposed 14,102 · Balance 0

F6: Each American Depositary Share represents 13 Ordinary Shares.

F7: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F29: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $358.95 to $359.68, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Ordinary SharesSEC Table I · non-derivativeDirect1,330,988 Reported balance Holding disclosure · report date 2026-08-10 · row 1 Holding and transaction disclosures are not merged.
1 source row

Row 1 · Balance 1,330,988

Ordinary SharesSEC Table I · non-derivativeIndirectSee Footnote481,533 Reported balance Holding disclosure · report date 2026-08-10 · row 2 Holding and transaction disclosures are not merged.
1 source row

Row 2 · Balance 481,533

F1: These securities are held by the P&O Trust, the beneficiaries of which include the Reporting Person's child and others, for which the Reporting Person disclaims beneficial ownership.

Ordinary SharesSEC Table I · non-derivativeIndirectSee Footnote7,699,158 Reported balance Holding disclosure · report date 2026-08-10 · row 3 Holding and transaction disclosures are not merged.
1 source row

Row 3 · Balance 7,699,158

F2: These securities are held in a grantor retained annuity trust, of which the Reporting Person's father is a trustee, for which the Reporting Person disclaims beneficial ownership.

Ordinary SharesSEC Table I · non-derivativeIndirectSee Footnote28,204,115 Reported balance Holding disclosure · report date 2026-08-10 · row 4 Holding and transaction disclosures are not merged.
1 source row

Row 4 · Balance 28,204,115

F3: These securities are held by Oyler Investment LLC, of which 99% of the limited liability company interests are owned by a grantor retain annuity trust, of which the Reporting Person's father is a trustee, for which the Reporting Person disclaims beneficial ownership.

Ordinary SharesSEC Table I · non-derivativeIndirectSee Footnote9,545,000 Reported balance Holding disclosure · report date 2026-08-10 · row 5 Holding and transaction disclosures are not merged.
1 source row

Row 5 · Balance 9,545,000

F4: These securities are held for the benefit of the Reporting Person in a Roth IRA PENSCO trust account.

Ordinary SharesSEC Table I · non-derivativeIndirectSee Footnote102,188 Reported balance Holding disclosure · report date 2026-08-10 · row 6 Holding and transaction disclosures are not merged.
1 source row

Row 6 · Balance 102,188

F5: These securities are held by The John Oyler Legacy Trust for the benefit of the Reporting Person's child, for which the Reporting Person disclaims beneficial ownership.

Filing footnotes · ownership attribution and instrument terms

F1: These securities are held by the P&O Trust, the beneficiaries of which include the Reporting Person's child and others, for which the Reporting Person disclaims beneficial ownership.

F2: These securities are held in a grantor retained annuity trust, of which the Reporting Person's father is a trustee, for which the Reporting Person disclaims beneficial ownership.

F3: These securities are held by Oyler Investment LLC, of which 99% of the limited liability company interests are owned by a grantor retain annuity trust, of which the Reporting Person's father is a trustee, for which the Reporting Person disclaims beneficial ownership.

F4: These securities are held for the benefit of the Reporting Person in a Roth IRA PENSCO trust account.

F5: These securities are held by The John Oyler Legacy Trust for the benefit of the Reporting Person's child, for which the Reporting Person disclaims beneficial ownership.

F6: Each American Depositary Share represents 13 Ordinary Shares.

F7: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F8: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $351.01 to $351.99, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

F9: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $353.00 to $353.99, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

F10: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $354.03 to $355.01, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

F11: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $355.08 to $356.05, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

F12: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $356.08 to $357.06, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

F13: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $357.08 to $358.07, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

F14: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $358.08 to $359.07, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

F15: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $359.08 to $360.00, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

F16: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $360.25 to $361.14, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

F17: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $358.90 to $359.89, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

F18: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $359.92 to $360.91, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

F19: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $360.92 to $361.91, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

F20: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $361.94 to $362.74, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

F21: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $362.95 to $363.94, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

F22: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $363.95 to $364.90, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

F23: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $365.00 to $365.90, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

F24: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $366.00 to $366.99, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

F25: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $354.35 to $355.05, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

F26: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $355.92 to $356.91, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

F27: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $356.95 to $357.94, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

F28: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $357.95 to $358.94, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

F29: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $358.95 to $359.68, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
July 17, 2026 Filed Jul 17, 2026 21:36 UTC BeOne Medicines Ltd. ONC · Entity 2168 Exercise / conversionAmerican Depositary Shares 64,628 $119.96 $7,752,774.88
Disclosure

SEC source: 0001042047-26-000015 · wk-form4_1784324169.xml · nonDerivative · entry 7

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 64,628

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · security: Each American Depositary Share represents 13 Ordinary Shares.

Read SEC document
July 16, 2026 Filed Jul 17, 2026 21:31 UTC BeOne Medicines Ltd. ONC · Entity 2168 Exercise / conversionShare Option (Right to Buy) · Derivative 911,248 $0.00 Strike: $9.23 $0.00
Disclosure

SEC source: 0001042047-26-000014 · wk-form4_1784323860.xml · derivative · entry 33

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,282,034

Underlying: Ordinary Shares · 911,248 shares

Expires 2029-06-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F24 · derivative.exercise_price: The number of securities underlying each option and the exercise price therefore are represented in ordinary shares.

F28 · derivative.exercise_date: These securities vest over a four-year period as follows: 25% on June 5, 2020, and the remaining in 36 successive equal monthly installments, subject to continued service. Unvested shares are subject to accelerated vesting upon a change in control or certain termination events.

Read SEC document
July 16, 2026 Filed Jul 17, 2026 21:31 UTC BeOne Medicines Ltd. ONC · Entity 2168 Exercise / conversionShare Option (Right to Buy) · Derivative 1,254,513 $0.00 Strike: $12.34 $0.00
Disclosure

SEC source: 0001042047-26-000014 · wk-form4_1784323860.xml · derivative · entry 32

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Ordinary Shares · 1,254,513 shares

Expires 2028-06-25

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F24 · derivative.exercise_price: The number of securities underlying each option and the exercise price therefore are represented in ordinary shares.

F27 · derivative.exercise_date: These securities vest over a four-year period as follows: 25% on June 26, 2019, and the remaining in 36 successive equal monthly installments, subject to continued service. Unvested shares are subject to accelerated vesting upon a change in control or certain termination events.

Read SEC document
July 16, 2026 Filed Jul 17, 2026 21:31 UTC BeOne Medicines Ltd. ONC · Entity 2168 SaleAmerican Depositary Shares 520 $323.59 $168,264.62
Disclosure

SEC source: 0001042047-26-000014 · wk-form4_1784323860.xml · nonDerivative · entry 28

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

F6 · security: Each American Depositary Share represents 13 Ordinary Shares.

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F23 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $323.495 to $323.625, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Read SEC document
July 16, 2026 Filed Jul 17, 2026 21:31 UTC BeOne Medicines Ltd. ONC · Entity 2168 SaleAmerican Depositary Shares 1,560 $322.71 $503,423.86
Disclosure

SEC source: 0001042047-26-000014 · wk-form4_1784323860.xml · nonDerivative · entry 27

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 520

F6 · security: Each American Depositary Share represents 13 Ordinary Shares.

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F22 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $322.455 to $323.405, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Read SEC document
July 16, 2026 Filed Jul 17, 2026 21:31 UTC BeOne Medicines Ltd. ONC · Entity 2168 SaleAmerican Depositary Shares 13,109 $321.61 $4,216,020.88
Disclosure

SEC source: 0001042047-26-000014 · wk-form4_1784323860.xml · nonDerivative · entry 26

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 2,080

F6 · security: Each American Depositary Share represents 13 Ordinary Shares.

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F21 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $321.39 to $322.33, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Read SEC document
July 16, 2026 Filed Jul 17, 2026 21:31 UTC BeOne Medicines Ltd. ONC · Entity 2168 SaleAmerican Depositary Shares 20,505 $321.00 $6,582,063.99
Disclosure

SEC source: 0001042047-26-000014 · wk-form4_1784323860.xml · nonDerivative · entry 25

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 15,189

F6 · security: Each American Depositary Share represents 13 Ordinary Shares.

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F20 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $320.38 to $321.35, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Read SEC document
July 16, 2026 Filed Jul 17, 2026 21:31 UTC BeOne Medicines Ltd. ONC · Entity 2168 SaleAmerican Depositary Shares 15,097 $319.99 $4,830,934.32
Disclosure

SEC source: 0001042047-26-000014 · wk-form4_1784323860.xml · nonDerivative · entry 24

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 35,694

F6 · security: Each American Depositary Share represents 13 Ordinary Shares.

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F19 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $319.36 to $320.34, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Read SEC document
July 16, 2026 Filed Jul 17, 2026 21:31 UTC BeOne Medicines Ltd. ONC · Entity 2168 SaleAmerican Depositary Shares 6,402 $318.55 $2,039,352.62
Disclosure

SEC source: 0001042047-26-000014 · wk-form4_1784323860.xml · nonDerivative · entry 23

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 50,791

F6 · security: Each American Depositary Share represents 13 Ordinary Shares.

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F18 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $318.30 to $319.11, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Read SEC document
July 16, 2026 Filed Jul 17, 2026 21:31 UTC BeOne Medicines Ltd. ONC · Entity 2168 SaleAmerican Depositary Shares 42,798 $317.79 $13,600,720.78
Disclosure

SEC source: 0001042047-26-000014 · wk-form4_1784323860.xml · nonDerivative · entry 22

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 57,193

F6 · security: Each American Depositary Share represents 13 Ordinary Shares.

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F17 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $317.28 to $318.265, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Read SEC document
July 16, 2026 Filed Jul 17, 2026 21:31 UTC BeOne Medicines Ltd. ONC · Entity 2168 SaleAmerican Depositary Shares 32,224 $316.82 $10,209,120.68
Disclosure

SEC source: 0001042047-26-000014 · wk-form4_1784323860.xml · nonDerivative · entry 21

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 99,991

F6 · security: Each American Depositary Share represents 13 Ordinary Shares.

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F16 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $316.28 to $317.27, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Read SEC document
July 16, 2026 Filed Jul 17, 2026 21:31 UTC BeOne Medicines Ltd. ONC · Entity 2168 SaleAmerican Depositary Shares 19,752 $316.00 $6,241,632.00
Disclosure

SEC source: 0001042047-26-000014 · wk-form4_1784323860.xml · nonDerivative · entry 20

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 132,215

F6 · security: Each American Depositary Share represents 13 Ordinary Shares.

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F15 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $315.28 to $316.27, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Read SEC document
July 16, 2026 Filed Jul 17, 2026 21:31 UTC BeOne Medicines Ltd. ONC · Entity 2168 SaleAmerican Depositary Shares 9,516 $314.73 $2,994,987.81
Disclosure

SEC source: 0001042047-26-000014 · wk-form4_1784323860.xml · nonDerivative · entry 19

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 151,967

F6 · security: Each American Depositary Share represents 13 Ordinary Shares.

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F14 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $314.27 to $315.24, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Read SEC document
July 16, 2026 Filed Jul 17, 2026 21:31 UTC BeOne Medicines Ltd. ONC · Entity 2168 SaleAmerican Depositary Shares 4,881 $314.08 $1,533,010.81
Disclosure

SEC source: 0001042047-26-000014 · wk-form4_1784323860.xml · nonDerivative · entry 18

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 161,483

F6 · security: Each American Depositary Share represents 13 Ordinary Shares.

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F13 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $313.27 to $314.26, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Read SEC document
July 16, 2026 Filed Jul 17, 2026 21:31 UTC BeOne Medicines Ltd. ONC · Entity 2168 SaleAmerican Depositary Shares 233 $311.98 $72,691.34
Disclosure

SEC source: 0001042047-26-000014 · wk-form4_1784323860.xml · nonDerivative · entry 17

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 166,364

F6 · security: Each American Depositary Share represents 13 Ordinary Shares.

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

Read SEC document
July 16, 2026 Filed Jul 17, 2026 21:31 UTC BeOne Medicines Ltd. ONC · Entity 2168 Exercise / conversionAmerican Depositary Shares 70,096 $119.96 $8,408,716.16
Disclosure

SEC source: 0001042047-26-000014 · wk-form4_1784323860.xml · nonDerivative · entry 16

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 166,597

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · security: Each American Depositary Share represents 13 Ordinary Shares.

Read SEC document
July 16, 2026 Filed Jul 17, 2026 21:31 UTC BeOne Medicines Ltd. ONC · Entity 2168 Exercise / conversionAmerican Depositary Shares 96,501 $160.40 $15,478,760.40
Disclosure

SEC source: 0001042047-26-000014 · wk-form4_1784323860.xml · nonDerivative · entry 15

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 96,501

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · security: Each American Depositary Share represents 13 Ordinary Shares.

Read SEC document
July 15, 2026 Filed Jul 17, 2026 21:31 UTC BeOne Medicines Ltd. ONC · Entity 2168 Exercise / conversionShare Option (Right to Buy) · Derivative 55,575 $0.00 Strike: $12.34 $0.00
Disclosure

SEC source: 0001042047-26-000014 · wk-form4_1784323860.xml · derivative · entry 31

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,254,513

Underlying: Ordinary Shares · 55,575 shares

Expires 2028-06-25

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F24 · derivative.exercise_price: The number of securities underlying each option and the exercise price therefore are represented in ordinary shares.

F27 · derivative.exercise_date: These securities vest over a four-year period as follows: 25% on June 26, 2019, and the remaining in 36 successive equal monthly installments, subject to continued service. Unvested shares are subject to accelerated vesting upon a change in control or certain termination events.

Read SEC document
July 15, 2026 Filed Jul 17, 2026 21:31 UTC BeOne Medicines Ltd. ONC · Entity 2168 Exercise / conversionShare Option (Right to Buy) · Derivative 996,801 $0.00 Strike: $13.05 $0.00
Disclosure

SEC source: 0001042047-26-000014 · wk-form4_1784323860.xml · derivative · entry 30

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 9

Underlying: Ordinary Shares · 996,801 shares

Expires 2028-04-29

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F24 · derivative.exercise_price: The number of securities underlying each option and the exercise price therefore are represented in ordinary shares.

F26 · derivative.exercise_date: These securities vest over a four-year period as follows: 25% on April 30, 2019, and the remaining in 36 successive equal monthly installments, subject to continued service. Unvested shares are subject to accelerated vesting upon a change in control or certain termination events.

Read SEC document
July 15, 2026 Filed Jul 17, 2026 21:31 UTC BeOne Medicines Ltd. ONC · Entity 2168 Exercise / conversionShare Option (Right to Buy) · Derivative 462,865 $0.00 Strike: $7.70 $0.00
Disclosure

SEC source: 0001042047-26-000014 · wk-form4_1784323860.xml · derivative · entry 29

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1

Underlying: Ordinary Shares · 462,865 shares

Expires 2027-09-26

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F24 · derivative.exercise_price: The number of securities underlying each option and the exercise price therefore are represented in ordinary shares.

F25 · derivative.exercise_date: These securities vest over a four-year period as follows: 25% on June 30, 2018, and the remaining in 36 successive equal monthly installments, subject to continued service. Unvested shares are subject to accelerated vesting upon a change in control or certain termination events.

Read SEC document
July 15, 2026 Filed Jul 17, 2026 21:31 UTC BeOne Medicines Ltd. ONC · Entity 2168 SaleAmerican Depositary Shares 7,640 $313.58 $2,395,745.85
Disclosure

SEC source: 0001042047-26-000014 · wk-form4_1784323860.xml · nonDerivative · entry 14

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

F6 · security: Each American Depositary Share represents 13 Ordinary Shares.

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F12 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $313.36 to $313.90, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Read SEC document
July 15, 2026 Filed Jul 17, 2026 21:31 UTC BeOne Medicines Ltd. ONC · Entity 2168 SaleAmerican Depositary Shares 48,657 $312.86 $15,222,746.30
Disclosure

SEC source: 0001042047-26-000014 · wk-form4_1784323860.xml · nonDerivative · entry 13

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 7,640

F6 · security: Each American Depositary Share represents 13 Ordinary Shares.

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F11 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $312.35 to $313.345, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Read SEC document
July 15, 2026 Filed Jul 17, 2026 21:31 UTC BeOne Medicines Ltd. ONC · Entity 2168 SaleAmerican Depositary Shares 12,857 $311.71 $4,007,685.04
Disclosure

SEC source: 0001042047-26-000014 · wk-form4_1784323860.xml · nonDerivative · entry 12

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 56,297

F6 · security: Each American Depositary Share represents 13 Ordinary Shares.

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F10 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $311.35 to $312.34, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Read SEC document
July 15, 2026 Filed Jul 17, 2026 21:31 UTC BeOne Medicines Ltd. ONC · Entity 2168 SaleAmerican Depositary Shares 41,336 $310.92 $12,852,304.86
Disclosure

SEC source: 0001042047-26-000014 · wk-form4_1784323860.xml · nonDerivative · entry 11

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 69,154

F6 · security: Each American Depositary Share represents 13 Ordinary Shares.

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F9 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $310.35 to $311.34, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Read SEC document
July 15, 2026 Filed Jul 17, 2026 21:31 UTC BeOne Medicines Ltd. ONC · Entity 2168 SaleAmerican Depositary Shares 6,067 $310.02 $1,880,891.95
Disclosure

SEC source: 0001042047-26-000014 · wk-form4_1784323860.xml · nonDerivative · entry 10

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 110,490

F6 · security: Each American Depositary Share represents 13 Ordinary Shares.

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F8 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $309.31 to $310.30, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Read SEC document
July 15, 2026 Filed Jul 17, 2026 21:31 UTC BeOne Medicines Ltd. ONC · Entity 2168 Exercise / conversionAmerican Depositary Shares 4,275 $160.40 $685,710.00
Disclosure

SEC source: 0001042047-26-000014 · wk-form4_1784323860.xml · nonDerivative · entry 9

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 116,557

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · security: Each American Depositary Share represents 13 Ordinary Shares.

Read SEC document
July 15, 2026 Filed Jul 17, 2026 21:31 UTC BeOne Medicines Ltd. ONC · Entity 2168 Exercise / conversionAmerican Depositary Shares 76,677 $169.58 $13,002,885.66
Disclosure

SEC source: 0001042047-26-000014 · wk-form4_1784323860.xml · nonDerivative · entry 8

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 112,282

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · security: Each American Depositary Share represents 13 Ordinary Shares.

Read SEC document
July 15, 2026 Filed Jul 17, 2026 21:31 UTC BeOne Medicines Ltd. ONC · Entity 2168 Exercise / conversionAmerican Depositary Shares 35,605 $100.04 $3,561,924.20
Disclosure

SEC source: 0001042047-26-000014 · wk-form4_1784323860.xml · nonDerivative · entry 7

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 35,605

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · security: Each American Depositary Share represents 13 Ordinary Shares.

Read SEC document
July 14, 2026 Filed Jul 15, 2026 01:26 UTC BeOne Medicines Ltd. ONC · Entity 2168 Exercise / conversionShare Option (Right to Buy) · Derivative 472,134 $0.00 Strike: $7.70 $0.00
Disclosure

SEC source: 0001042047-26-000013 · wk-form4_1784078797.xml · derivative · entry 16

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 462,866

Underlying: Ordinary Shares · 472,134 shares

Expires 2027-09-26

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F16 · derivative.exercise_price: The number of securities underlying each option and the exercise price therefore are represented in ordinary shares. The exercise price is equal to 1/13 of the closing price of our American Depositary Shares ("ADSs") on the date of grant, as each ADS represents 13 ordinary shares.

F17 · derivative.exercise_date: These securities vest over a four-year period as follows: 25% on June 30, 2018, and the remaining in 36 successive equal monthly installments, subject to continued service. Unvested shares are subject to accelerated vesting upon a change in control or certain termination events.

Read SEC document
July 14, 2026 Filed Jul 15, 2026 01:26 UTC BeOne Medicines Ltd. ONC · Entity 2168 Exercise / conversionShare Option (Right to Buy) · Derivative 1,264,666 $0.00 Strike: $2.84 $0.00
Disclosure

SEC source: 0001042047-26-000013 · wk-form4_1784078797.xml · derivative · entry 15

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Ordinary Shares · 1,264,666 shares

Expires 2026-11-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F14 · derivative.exercise_price: The number of securities underlying each option and the exercise price therefore are represented in ordinary shares.

F15 · derivative.exercise_date: These securities vest over a four-year period as follows: 25% on July 13, 2017, and the remaining in 36 successive equal monthly installments, subject to continued service. Unvested shares subject to this option are subject to accelerated vesting upon a change in control or certain termination events.

Read SEC document
July 14, 2026 Filed Jul 15, 2026 01:26 UTC BeOne Medicines Ltd. ONC · Entity 2168 SaleAmerican Depositary Shares 7,834 $307.57 $2,409,533.93
Disclosure

SEC source: 0001042047-26-000013 · wk-form4_1784078797.xml · nonDerivative · entry 14

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

F6 · security: Each American Depositary Share represents 13 Ordinary Shares.

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F13 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $307.46 to $307.87, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Read SEC document
July 14, 2026 Filed Jul 15, 2026 01:26 UTC BeOne Medicines Ltd. ONC · Entity 2168 SaleAmerican Depositary Shares 40,781 $306.93 $12,517,112.16
Disclosure

SEC source: 0001042047-26-000013 · wk-form4_1784078797.xml · nonDerivative · entry 13

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 7,834

F6 · security: Each American Depositary Share represents 13 Ordinary Shares.

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F12 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $306.455 to $307.44, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Read SEC document
July 14, 2026 Filed Jul 15, 2026 01:26 UTC BeOne Medicines Ltd. ONC · Entity 2168 SaleAmerican Depositary Shares 45,895 $306.21 $14,053,627.28
Disclosure

SEC source: 0001042047-26-000013 · wk-form4_1784078797.xml · nonDerivative · entry 12

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 48,615

F6 · security: Each American Depositary Share represents 13 Ordinary Shares.

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F11 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $305.455 to $306.45, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

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July 14, 2026 Filed Jul 15, 2026 01:26 UTC BeOne Medicines Ltd. ONC · Entity 2168 SaleAmerican Depositary Shares 39,090 $305.02 $11,923,259.16
Disclosure

SEC source: 0001042047-26-000013 · wk-form4_1784078797.xml · nonDerivative · entry 11

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 94,510

F6 · security: Each American Depositary Share represents 13 Ordinary Shares.

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F10 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $304.45 to $305.44, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

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July 14, 2026 Filed Jul 15, 2026 01:26 UTC BeOne Medicines Ltd. ONC · Entity 2168 Exercise / conversionAmerican Depositary Shares 36,318 $100.04 $3,633,252.72
Disclosure

SEC source: 0001042047-26-000013 · wk-form4_1784078797.xml · nonDerivative · entry 10

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 133,600

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · security: Each American Depositary Share represents 13 Ordinary Shares.

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July 14, 2026 Filed Jul 15, 2026 01:26 UTC BeOne Medicines Ltd. ONC · Entity 2168 Exercise / conversionAmerican Depositary Shares 97,282 $36.90 $3,589,705.80
Disclosure

SEC source: 0001042047-26-000013 · wk-form4_1784078797.xml · nonDerivative · entry 9

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 97,282

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · security: Each American Depositary Share represents 13 Ordinary Shares.

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July 14, 2026 Filed Jul 15, 2026 01:26 UTC BeOne Medicines Ltd. ONC · Entity 2168 SaleAmerican Depositary Shares 8,122 $303.93 $2,468,490.22
Disclosure

SEC source: 0001042047-26-000013 · wk-form4_1784078797.xml · nonDerivative · entry 8

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

F6 · security: Each American Depositary Share represents 13 Ordinary Shares.

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F9 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $303.54 to $304.43, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

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July 14, 2026 Filed Jul 15, 2026 01:26 UTC BeOne Medicines Ltd. ONC · Entity 2168 SaleAmerican Depositary Shares 4,139 $303.07 $1,254,401.35
Disclosure

SEC source: 0001042047-26-000013 · wk-form4_1784078797.xml · nonDerivative · entry 7

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 8,122

F6 · security: Each American Depositary Share represents 13 Ordinary Shares.

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F8 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $302.48 to $303.46, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

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July 13, 2026 Filed Jul 15, 2026 01:25 UTC BeOne Medicines Ltd. ONC · Entity 2168 Exercise / conversionShare Option (Right to Buy) · Derivative 630,760 $0.00 Strike: $2.84 $0.00
Disclosure

SEC source: 0001042047-26-000011 · wk-form4_1784078719.xml · derivative · entry 25

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,264,666

Underlying: Ordinary Shares · 630,760 shares

Expires 2026-11-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F22 · derivative.exercise_price: The number of securities underlying each option and the exercise price therefore are represented in ordinary shares.

F23 · derivative.exercise_date: These securities vest over a four-year period as follows: 25% on July 13, 2017, and the remaining in 36 successive equal monthly installments, subject to continued service. Unvested shares subject to this option are subject to accelerated vesting upon a change in control or certain termination events.

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July 13, 2026 Filed Jul 15, 2026 01:25 UTC BeOne Medicines Ltd. ONC · Entity 2168 SaleAmerican Depositary Shares 320 $307.41 $98,369.60
Disclosure

SEC source: 0001042047-26-000011 · wk-form4_1784078719.xml · nonDerivative · entry 23

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

F6 · security: Each American Depositary Share represents 13 Ordinary Shares.

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F21 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $307.35 to $307.44, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

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July 13, 2026 Filed Jul 15, 2026 01:25 UTC BeOne Medicines Ltd. ONC · Entity 2168 SaleAmerican Depositary Shares 7,240 $306.82 $2,221,409.38
Disclosure

SEC source: 0001042047-26-000011 · wk-form4_1784078719.xml · nonDerivative · entry 22

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 320

F6 · security: Each American Depositary Share represents 13 Ordinary Shares.

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F20 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $306.32 to $307.26, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

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July 13, 2026 Filed Jul 15, 2026 01:25 UTC BeOne Medicines Ltd. ONC · Entity 2168 SaleAmerican Depositary Shares 846 $305.57 $258,508.33
Disclosure

SEC source: 0001042047-26-000011 · wk-form4_1784078719.xml · nonDerivative · entry 21

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 7,560

F6 · security: Each American Depositary Share represents 13 Ordinary Shares.

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F19 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $305.30 to $306.23, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

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July 13, 2026 Filed Jul 15, 2026 01:25 UTC BeOne Medicines Ltd. ONC · Entity 2168 SaleAmerican Depositary Shares 8,438 $304.68 $2,570,892.37
Disclosure

SEC source: 0001042047-26-000011 · wk-form4_1784078719.xml · nonDerivative · entry 20

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 8,406

F6 · security: Each American Depositary Share represents 13 Ordinary Shares.

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F18 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $304.30 to $305.26, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

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July 13, 2026 Filed Jul 15, 2026 01:25 UTC BeOne Medicines Ltd. ONC · Entity 2168 SaleAmerican Depositary Shares 26,294 $303.83 $7,988,777.18
Disclosure

SEC source: 0001042047-26-000011 · wk-form4_1784078719.xml · nonDerivative · entry 19

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 16,844

F6 · security: Each American Depositary Share represents 13 Ordinary Shares.

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F17 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $303.30 to $304.29, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

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July 13, 2026 Filed Jul 15, 2026 01:25 UTC BeOne Medicines Ltd. ONC · Entity 2168 SaleAmerican Depositary Shares 4,584 $302.79 $1,387,980.65
Disclosure

SEC source: 0001042047-26-000011 · wk-form4_1784078719.xml · nonDerivative · entry 18

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 43,138

F6 · security: Each American Depositary Share represents 13 Ordinary Shares.

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F16 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $302.29 to $303.27, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

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July 13, 2026 Filed Jul 15, 2026 01:25 UTC BeOne Medicines Ltd. ONC · Entity 2168 SaleAmerican Depositary Shares 798 $301.94 $240,945.25
Disclosure

SEC source: 0001042047-26-000011 · wk-form4_1784078719.xml · nonDerivative · entry 17

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 47,722

F6 · security: Each American Depositary Share represents 13 Ordinary Shares.

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F15 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $301.23 to $302.19, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

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July 13, 2026 Filed Jul 15, 2026 01:25 UTC BeOne Medicines Ltd. ONC · Entity 2168 Exercise / conversionAmerican Depositary Shares 48,520 $36.90 $1,790,388.00
Disclosure

SEC source: 0001042047-26-000011 · wk-form4_1784078719.xml · nonDerivative · entry 16

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 48,520

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · security: Each American Depositary Share represents 13 Ordinary Shares.

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July 10, 2026 Filed Jul 15, 2026 01:25 UTC BeOne Medicines Ltd. ONC · Entity 2168 Exercise / conversionShare Option (Right to Buy) · Derivative 152,074 $0.00 Strike: $2.84 $0.00
Disclosure

SEC source: 0001042047-26-000011 · wk-form4_1784078719.xml · derivative · entry 24

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,895,426

Underlying: Ordinary Shares · 152,074 shares

Expires 2026-11-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F22 · derivative.exercise_price: The number of securities underlying each option and the exercise price therefore are represented in ordinary shares.

F23 · derivative.exercise_date: These securities vest over a four-year period as follows: 25% on July 13, 2017, and the remaining in 36 successive equal monthly installments, subject to continued service. Unvested shares subject to this option are subject to accelerated vesting upon a change in control or certain termination events.

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July 10, 2026 Filed Jul 15, 2026 01:25 UTC BeOne Medicines Ltd. ONC · Entity 2168 SaleAmerican Depositary Shares 18 $303.03 $5,454.54
Disclosure

SEC source: 0001042047-26-000011 · wk-form4_1784078719.xml · nonDerivative · entry 15

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

F6 · security: Each American Depositary Share represents 13 Ordinary Shares.

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

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July 10, 2026 Filed Jul 15, 2026 01:25 UTC BeOne Medicines Ltd. ONC · Entity 2168 SaleAmerican Depositary Shares 136 $302.19 $41,097.99
Disclosure

SEC source: 0001042047-26-000011 · wk-form4_1784078719.xml · nonDerivative · entry 14

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 18

F6 · security: Each American Depositary Share represents 13 Ordinary Shares.

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.

F14 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $301.95 to $302.25, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.