Hedley Mary Lynne

SEC source: 0001628280-26-060514 · wk-form4_1788469863.xml · derivative · entry 2

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,429

Underlying: Class A Common Stock · 477 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each Restricted Stock Unit ("RSU") represents a contingent right to receive one share of Class A Common Stock of the Issuer.

F1 · kind: Transaction exempt from Section 16(b) of the Securities Exchange Act of 1934 (the "Act") pursuant to Rule 16b-6(b) promulgated under the Act.

F3 · derivative.exercise_date: On June 17, 2026, the Reporting Person was granted 1,906 RSUs under the Issuer's Amended & Restated 2013 Equity Incentive Plan, of which 1/4 of the RSUs vested on September 1, 2026, with the remaining RSUs vesting equally on a quarterly basis thereafter, subject to continued service on the Issuer's board of directors on the applicable vesting date.

F3 · derivative.expiration_date: On June 17, 2026, the Reporting Person was granted 1,906 RSUs under the Issuer's Amended & Restated 2013 Equity Incentive Plan, of which 1/4 of the RSUs vested on September 1, 2026, with the remaining RSUs vesting equally on a quarterly basis thereafter, subject to continued service on the Issuer's board of directors on the applicable vesting date.

SEC source: 0001628280-26-060514 · wk-form4_1788469863.xml · nonDerivative · entry 1

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,629

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction exempt from Section 16(b) of the Securities Exchange Act of 1934 (the "Act") pursuant to Rule 16b-6(b) promulgated under the Act.

SEC source: 0001470831-26-000614 · wk-form4_1782332163.xml · derivative · entry 5

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Ordinary Shares · 40,000 shares

Expires 2035-06-20

F1 · kind: On June 24, 2026, Eli Lilly and Company ("Parent"), through its wholly owned subsidiary LDH XV Corporation ("Purchaser"), acquired all outstanding Ordinary Shares of Centessa Pharmaceuticals plc (the "Company") by means of a scheme of arrangement under Part 26 of the UK Companies Act 2006 (the "Scheme of Arrangement"), pursuant to the Transaction Agreement dated as of March 31, 2026, by and among the Company, Parent and Purchaser (the "Transaction Agreement").

F2 · price: Pursuant to the Transaction Agreement, at the effective time of the Scheme of Arrangement, each outstanding share option, whether or not vested, was automatically cancelled and converted into the right to receive (i) an amount in cash equal to the excess of $38.00 in cash over the per-share exercise price of such option, without interest and less any applicable withholding taxes, and (ii) one non-transferable contingent value right (a "CVR") per underlying Ordinary Share entitling the holders to receive contingent payments of up to an aggregate of $9.00 per Ordinary Share, without interest and less any applicable withholding taxes, contingent upon the achievement of specified milestones set forth in the Contingent Value Rights Agreement between Parent, Purchaser and a rights agent mutually agreeable to the Company and Parent, in each case in accordance with the Transaction Agreement. No share options were exercised prior to the Effective Time.

F2 · derivative.exercise_date: Pursuant to the Transaction Agreement, at the effective time of the Scheme of Arrangement, each outstanding share option, whether or not vested, was automatically cancelled and converted into the right to receive (i) an amount in cash equal to the excess of $38.00 in cash over the per-share exercise price of such option, without interest and less any applicable withholding taxes, and (ii) one non-transferable contingent value right (a "CVR") per underlying Ordinary Share entitling the holders to receive contingent payments of up to an aggregate of $9.00 per Ordinary Share, without interest and less any applicable withholding taxes, contingent upon the achievement of specified milestones set forth in the Contingent Value Rights Agreement between Parent, Purchaser and a rights agent mutually agreeable to the Company and Parent, in each case in accordance with the Transaction Agreement. No share options were exercised prior to the Effective Time.

F3 · derivative.underlying: The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents one Ordinary Share.

SEC source: 0001470831-26-000614 · wk-form4_1782332163.xml · derivative · entry 4

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Ordinary Shares · 48,000 shares

Expires 2034-06-25

F1 · kind: On June 24, 2026, Eli Lilly and Company ("Parent"), through its wholly owned subsidiary LDH XV Corporation ("Purchaser"), acquired all outstanding Ordinary Shares of Centessa Pharmaceuticals plc (the "Company") by means of a scheme of arrangement under Part 26 of the UK Companies Act 2006 (the "Scheme of Arrangement"), pursuant to the Transaction Agreement dated as of March 31, 2026, by and among the Company, Parent and Purchaser (the "Transaction Agreement").

F2 · price: Pursuant to the Transaction Agreement, at the effective time of the Scheme of Arrangement, each outstanding share option, whether or not vested, was automatically cancelled and converted into the right to receive (i) an amount in cash equal to the excess of $38.00 in cash over the per-share exercise price of such option, without interest and less any applicable withholding taxes, and (ii) one non-transferable contingent value right (a "CVR") per underlying Ordinary Share entitling the holders to receive contingent payments of up to an aggregate of $9.00 per Ordinary Share, without interest and less any applicable withholding taxes, contingent upon the achievement of specified milestones set forth in the Contingent Value Rights Agreement between Parent, Purchaser and a rights agent mutually agreeable to the Company and Parent, in each case in accordance with the Transaction Agreement. No share options were exercised prior to the Effective Time.

F2 · derivative.exercise_date: Pursuant to the Transaction Agreement, at the effective time of the Scheme of Arrangement, each outstanding share option, whether or not vested, was automatically cancelled and converted into the right to receive (i) an amount in cash equal to the excess of $38.00 in cash over the per-share exercise price of such option, without interest and less any applicable withholding taxes, and (ii) one non-transferable contingent value right (a "CVR") per underlying Ordinary Share entitling the holders to receive contingent payments of up to an aggregate of $9.00 per Ordinary Share, without interest and less any applicable withholding taxes, contingent upon the achievement of specified milestones set forth in the Contingent Value Rights Agreement between Parent, Purchaser and a rights agent mutually agreeable to the Company and Parent, in each case in accordance with the Transaction Agreement. No share options were exercised prior to the Effective Time.

F3 · derivative.underlying: The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents one Ordinary Share.

SEC source: 0001470831-26-000614 · wk-form4_1782332163.xml · derivative · entry 3

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Ordinary Shares · 48,000 shares

Expires 2033-06-22

F1 · kind: On June 24, 2026, Eli Lilly and Company ("Parent"), through its wholly owned subsidiary LDH XV Corporation ("Purchaser"), acquired all outstanding Ordinary Shares of Centessa Pharmaceuticals plc (the "Company") by means of a scheme of arrangement under Part 26 of the UK Companies Act 2006 (the "Scheme of Arrangement"), pursuant to the Transaction Agreement dated as of March 31, 2026, by and among the Company, Parent and Purchaser (the "Transaction Agreement").

F2 · price: Pursuant to the Transaction Agreement, at the effective time of the Scheme of Arrangement, each outstanding share option, whether or not vested, was automatically cancelled and converted into the right to receive (i) an amount in cash equal to the excess of $38.00 in cash over the per-share exercise price of such option, without interest and less any applicable withholding taxes, and (ii) one non-transferable contingent value right (a "CVR") per underlying Ordinary Share entitling the holders to receive contingent payments of up to an aggregate of $9.00 per Ordinary Share, without interest and less any applicable withholding taxes, contingent upon the achievement of specified milestones set forth in the Contingent Value Rights Agreement between Parent, Purchaser and a rights agent mutually agreeable to the Company and Parent, in each case in accordance with the Transaction Agreement. No share options were exercised prior to the Effective Time.

F2 · derivative.exercise_date: Pursuant to the Transaction Agreement, at the effective time of the Scheme of Arrangement, each outstanding share option, whether or not vested, was automatically cancelled and converted into the right to receive (i) an amount in cash equal to the excess of $38.00 in cash over the per-share exercise price of such option, without interest and less any applicable withholding taxes, and (ii) one non-transferable contingent value right (a "CVR") per underlying Ordinary Share entitling the holders to receive contingent payments of up to an aggregate of $9.00 per Ordinary Share, without interest and less any applicable withholding taxes, contingent upon the achievement of specified milestones set forth in the Contingent Value Rights Agreement between Parent, Purchaser and a rights agent mutually agreeable to the Company and Parent, in each case in accordance with the Transaction Agreement. No share options were exercised prior to the Effective Time.

F3 · derivative.underlying: The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents one Ordinary Share.

SEC source: 0001470831-26-000614 · wk-form4_1782332163.xml · derivative · entry 2

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Ordinary Shares · 48,000 shares

Expires 2032-06-30

F1 · kind: On June 24, 2026, Eli Lilly and Company ("Parent"), through its wholly owned subsidiary LDH XV Corporation ("Purchaser"), acquired all outstanding Ordinary Shares of Centessa Pharmaceuticals plc (the "Company") by means of a scheme of arrangement under Part 26 of the UK Companies Act 2006 (the "Scheme of Arrangement"), pursuant to the Transaction Agreement dated as of March 31, 2026, by and among the Company, Parent and Purchaser (the "Transaction Agreement").

F2 · price: Pursuant to the Transaction Agreement, at the effective time of the Scheme of Arrangement, each outstanding share option, whether or not vested, was automatically cancelled and converted into the right to receive (i) an amount in cash equal to the excess of $38.00 in cash over the per-share exercise price of such option, without interest and less any applicable withholding taxes, and (ii) one non-transferable contingent value right (a "CVR") per underlying Ordinary Share entitling the holders to receive contingent payments of up to an aggregate of $9.00 per Ordinary Share, without interest and less any applicable withholding taxes, contingent upon the achievement of specified milestones set forth in the Contingent Value Rights Agreement between Parent, Purchaser and a rights agent mutually agreeable to the Company and Parent, in each case in accordance with the Transaction Agreement. No share options were exercised prior to the Effective Time.

F2 · derivative.exercise_date: Pursuant to the Transaction Agreement, at the effective time of the Scheme of Arrangement, each outstanding share option, whether or not vested, was automatically cancelled and converted into the right to receive (i) an amount in cash equal to the excess of $38.00 in cash over the per-share exercise price of such option, without interest and less any applicable withholding taxes, and (ii) one non-transferable contingent value right (a "CVR") per underlying Ordinary Share entitling the holders to receive contingent payments of up to an aggregate of $9.00 per Ordinary Share, without interest and less any applicable withholding taxes, contingent upon the achievement of specified milestones set forth in the Contingent Value Rights Agreement between Parent, Purchaser and a rights agent mutually agreeable to the Company and Parent, in each case in accordance with the Transaction Agreement. No share options were exercised prior to the Effective Time.

F3 · derivative.underlying: The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents one Ordinary Share.

SEC source: 0001470831-26-000614 · wk-form4_1782332163.xml · derivative · entry 1

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Ordinary Shares · 208,474 shares

Expires 2031-02-19

F1 · kind: On June 24, 2026, Eli Lilly and Company ("Parent"), through its wholly owned subsidiary LDH XV Corporation ("Purchaser"), acquired all outstanding Ordinary Shares of Centessa Pharmaceuticals plc (the "Company") by means of a scheme of arrangement under Part 26 of the UK Companies Act 2006 (the "Scheme of Arrangement"), pursuant to the Transaction Agreement dated as of March 31, 2026, by and among the Company, Parent and Purchaser (the "Transaction Agreement").

F2 · price: Pursuant to the Transaction Agreement, at the effective time of the Scheme of Arrangement, each outstanding share option, whether or not vested, was automatically cancelled and converted into the right to receive (i) an amount in cash equal to the excess of $38.00 in cash over the per-share exercise price of such option, without interest and less any applicable withholding taxes, and (ii) one non-transferable contingent value right (a "CVR") per underlying Ordinary Share entitling the holders to receive contingent payments of up to an aggregate of $9.00 per Ordinary Share, without interest and less any applicable withholding taxes, contingent upon the achievement of specified milestones set forth in the Contingent Value Rights Agreement between Parent, Purchaser and a rights agent mutually agreeable to the Company and Parent, in each case in accordance with the Transaction Agreement. No share options were exercised prior to the Effective Time.

F2 · derivative.exercise_date: Pursuant to the Transaction Agreement, at the effective time of the Scheme of Arrangement, each outstanding share option, whether or not vested, was automatically cancelled and converted into the right to receive (i) an amount in cash equal to the excess of $38.00 in cash over the per-share exercise price of such option, without interest and less any applicable withholding taxes, and (ii) one non-transferable contingent value right (a "CVR") per underlying Ordinary Share entitling the holders to receive contingent payments of up to an aggregate of $9.00 per Ordinary Share, without interest and less any applicable withholding taxes, contingent upon the achievement of specified milestones set forth in the Contingent Value Rights Agreement between Parent, Purchaser and a rights agent mutually agreeable to the Company and Parent, in each case in accordance with the Transaction Agreement. No share options were exercised prior to the Effective Time.

F3 · derivative.underlying: The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents one Ordinary Share.

SEC source: 0001628280-26-044672 · wk-form4_1782161095.xml · derivative · entry 2

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,906

Underlying: Class A Common Stock · 1,906 shares

Expires not disclosed

F1 · derivative.exercise_price: Each Restricted Stock Unit ("RSU") represents a contingent right to receive one share of Class A Common Stock of the Issuer.

F2 · derivative.exercise_date: The RSUs were granted under the Issuer's Amended & Restated 2013 Equity Incentive Plan. The Reporting Person vests ownership in the RSUs over one year with 1/4 of the RSUs vesting on September 1, 2026, and 1/4 of the RSUs vesting on a quarterly basis thereafter, subject to continued service to the Issuer by the Reporting Person.

F2 · derivative.expiration_date: The RSUs were granted under the Issuer's Amended & Restated 2013 Equity Incentive Plan. The Reporting Person vests ownership in the RSUs over one year with 1/4 of the RSUs vesting on September 1, 2026, and 1/4 of the RSUs vesting on a quarterly basis thereafter, subject to continued service to the Issuer by the Reporting Person.

SEC source: 0001628280-26-040422 · wk-form4_1780519116.xml · derivative · entry 2

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Class A Common Stock · 262 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each Restricted Stock Unit ("RSU") represents a contingent right to receive one share of Class A Common Stock of the Issuer.

F1 · kind: Transaction exempt from Section 16(b) of the Securities Exchange Act of 1934 (the "Act") pursuant to Rule 16b-6(b) promulgated under the Act.

F3 · derivative.exercise_date: On June 18, 2025, the Reporting Person was granted 1,049 RSUs under the Issuer's Amended & Restated 2013 Equity Incentive Plan, of which 1/4 of the RSUs vested on September 1, 2025, with the remaining RSUs vesting equally on a quarterly basis thereafter, subject to continued service on the Issuer's board of directors on the applicable vesting date.

F3 · derivative.expiration_date: On June 18, 2025, the Reporting Person was granted 1,049 RSUs under the Issuer's Amended & Restated 2013 Equity Incentive Plan, of which 1/4 of the RSUs vested on September 1, 2025, with the remaining RSUs vesting equally on a quarterly basis thereafter, subject to continued service on the Issuer's board of directors on the applicable vesting date.

SEC source: 0001628280-26-040422 · wk-form4_1780519116.xml · nonDerivative · entry 1

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,152

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction exempt from Section 16(b) of the Securities Exchange Act of 1934 (the "Act") pursuant to Rule 16b-6(b) promulgated under the Act.

SEC source: 0001628280-26-014013 · wk-form4_1772575452.xml · derivative · entry 2

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 262

Underlying: Class A Common Stock · 262 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each Restricted Stock Unit ("RSU") represents a contingent right to receive one share of Class A Common Stock of the Issuer.

F1 · kind: Transaction exempt from Section 16(b) of the Securities Exchange Act of 1934 (the "Act") pursuant to Rule 16b-6(b) promulgated under the Act.

F3 · derivative.exercise_date: On June 18, 2025, the Reporting Person was granted 1,049 RSUs under the Issuer's Amended & Restated 2013 Equity Incentive Plan, of which 1/4 of the RSUs vested on September 1, 2025, with the remaining RSUs vesting equally on a quarterly basis thereafter, subject to continued service on the Issuer's board of directors on the applicable vesting date.

F3 · derivative.expiration_date: On June 18, 2025, the Reporting Person was granted 1,049 RSUs under the Issuer's Amended & Restated 2013 Equity Incentive Plan, of which 1/4 of the RSUs vested on September 1, 2025, with the remaining RSUs vesting equally on a quarterly basis thereafter, subject to continued service on the Issuer's board of directors on the applicable vesting date.

SEC source: 0001628280-26-014013 · wk-form4_1772575452.xml · nonDerivative · entry 1

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,890

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction exempt from Section 16(b) of the Securities Exchange Act of 1934 (the "Act") pursuant to Rule 16b-6(b) promulgated under the Act.

SEC source: 0001340823-25-000012 · wk-form4_1765921413.xml · nonDerivative · entry 1

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,252.694

F1 · shares: At the election of the reporting person, the shares acquired pursuant to this filing have been deferred in lieu of cash compensation as stock units under the Lilly Directors' Deferral Plan and will be settled in shares of common stock following the reporting person's separation from service.

SEC source: 0001628280-25-054670 · wk-form4_1764701691.xml · derivative · entry 2

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 524

Underlying: Class A Common Stock · 263 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each Restricted Stock Unit ("RSU") represents a contingent right to receive one share of Class A Common Stock of the Issuer.

F1 · kind: Transaction exempt from Section 16(b) of the Securities Exchange Act of 1934 (the "Act") pursuant to Rule 16b-6(b) promulgated under the Act.

F3 · derivative.exercise_date: On June 18, 2025, the Reporting Person was granted 1,049 RSUs under the Issuer's Amended & Restated 2013 Equity Incentive Plan, of which 1/4 of the RSUs vested on September 1, 2025, with the remaining RSUs vesting equally on a quarterly basis thereafter, subject to continued service on the Issuer's board of directors on the applicable vesting date.

F3 · derivative.expiration_date: On June 18, 2025, the Reporting Person was granted 1,049 RSUs under the Issuer's Amended & Restated 2013 Equity Incentive Plan, of which 1/4 of the RSUs vested on September 1, 2025, with the remaining RSUs vesting equally on a quarterly basis thereafter, subject to continued service on the Issuer's board of directors on the applicable vesting date.

SEC source: 0001628280-25-054670 · wk-form4_1764701691.xml · nonDerivative · entry 1

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,628

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction exempt from Section 16(b) of the Securities Exchange Act of 1934 (the "Act") pursuant to Rule 16b-6(b) promulgated under the Act.

SEC source: 0001340823-25-000010 · wk-form4_1763500655.xml · nonDerivative · entry 2

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,240.861

SEC source: 0001340823-25-000010 · wk-form4_1763500655.xml · nonDerivative · entry 1

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,025.534

F1 · shares: At the election of the reporting person, the shares reported as acquired in this row have been deferred in lieu of cash compensation as stock units under the Lilly Directors' Deferral Plan and will be settled in shares of common stock following the reporting person's separation from service.

SEC source: 0001340823-25-000008 · wk-form4_1761164553.xml · nonDerivative · entry 1

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,015.828

F1 · shares: At the election of the reporting person, the shares acquired pursuant to this filing have been deferred in lieu of cash compensation as stock units under the Lilly Directors' Deferral Plan and will be settled in shares of common stock following the reporting person's separation from service.

SEC source: 0001340823-25-000006 · wk-form4_1758142082.xml · nonDerivative · entry 1

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,003.492

F1 · shares: At the election of the reporting person, the shares acquired pursuant to this filing have been deferred in lieu of cash compensation as stock units under the Lilly Directors' Deferral Plan and will be settled in shares of common stock following the reporting person's separation from service.

SEC source: 0001340823-25-000003 · wk-form4_1756940970.xml · derivative · entry 2

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 787

Underlying: Class A Common Stock · 262 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each Restricted Stock Unit ("RSU") represents a contingent right to receive one share of Class A Common Stock of the Issuer.

F1 · kind: Transaction exempt from Section 16(b) of the Securities Exchange Act of 1934 (the "Act") pursuant to Rule 16b-6(b) promulgated under the Act.

F3 · derivative.exercise_date: On June 18, 2025, the Reporting Person was granted 1,049 RSUs under the Issuer's Amended & Restated 2013 Equity Incentive Plan, of which 1/4 of the RSUs vested on September 1, 2025, with the remaining RSUs vesting equally on a quarterly basis thereafter, subject to continued service on the Issuer's board of directors on the applicable vesting date.

F3 · derivative.expiration_date: On June 18, 2025, the Reporting Person was granted 1,049 RSUs under the Issuer's Amended & Restated 2013 Equity Incentive Plan, of which 1/4 of the RSUs vested on September 1, 2025, with the remaining RSUs vesting equally on a quarterly basis thereafter, subject to continued service on the Issuer's board of directors on the applicable vesting date.

SEC source: 0001340823-25-000003 · wk-form4_1756940970.xml · nonDerivative · entry 1

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,365

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction exempt from Section 16(b) of the Securities Exchange Act of 1934 (the "Act") pursuant to Rule 16b-6(b) promulgated under the Act.

SEC source: 0000059478-25-000228 · wk-form4_1755634883.xml · nonDerivative · entry 1

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,986.78

F1 · shares: At the election of the reporting person, the shares acquired pursuant to this filing have been deferred in lieu of cash compensation as stock units under the Lilly Directors' Deferral Plan and will be settled in shares of common stock following the reporting person's separation from service.

SEC source: 0000059478-25-000188 · wk-form4_1753216439.xml · nonDerivative · entry 1

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,972.574

F1 · shares: At the election of the reporting person, the shares acquired pursuant to this filing have been deferred in lieu of cash compensation as stock units under the Lilly Directors' Deferral Plan and will be settled in shares of common stock following the reporting person's separation from service.

SEC source: 0001847903-25-000108 · wk-form4_1750795990.xml · derivative · entry 1

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 40,000

Underlying: Ordinary Shares · 40,000 shares

Expires 2035-06-20

F1 · derivative.exercise_date: The shares subject to such option will vest in full on the earlier of (i) the first anniversary of the grant date or (ii) the Issuer's next annual meeting of shareholders, subject to continued service as a director through the applicable vesting date.

F2 · derivative.underlying: The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents one Ordinary Share.

SEC source: 0001628280-25-032428 · wk-form4_1750452166.xml · derivative · entry 2

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,049

Underlying: Class A Common Stock · 1,049 shares

Expires not disclosed

F1 · derivative.exercise_price: Each Restricted Stock Unit ("RSU") represents a contingent right to receive one share of Class A Common Stock of the Issuer.

F2 · derivative.exercise_date: The RSUs were granted under the Issuer's Amended & Restated 2013 Equity Incentive Plan. The Reporting Person vests ownership in the RSUs over one year with 1/4 of the RSUs vesting on September 1, 2025, and 1/4 of the RSUs vesting on a quarterly basis thereafter, subject to continued service to the Issuer by the Reporting Person.

F2 · derivative.expiration_date: The RSUs were granted under the Issuer's Amended & Restated 2013 Equity Incentive Plan. The Reporting Person vests ownership in the RSUs over one year with 1/4 of the RSUs vesting on September 1, 2025, and 1/4 of the RSUs vesting on a quarterly basis thereafter, subject to continued service to the Issuer by the Reporting Person.

SEC source: 0000059478-25-000172 · wk-form4_1750198988.xml · nonDerivative · entry 1

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,959.563

F1 · shares: At the election of the reporting person, the shares acquired pursuant to this filing have been deferred in lieu of cash compensation as stock units under the Lilly Directors' Deferral Plan and will be settled in shares of common stock following the reporting person's separation from service.

SEC source: 0001628280-25-028918 · wk-form4_1748908890.xml · derivative · entry 2

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Class A Common Stock · 343 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each Restricted Stock Unit ("RSU") represents a contingent right to receive one share of Class A Common Stock of the Issuer.

F1 · kind: Transaction exempt from Section 16(b) of the Securities Exchange Act of 1934 (the "Act") pursuant to Rule 16b-6(b) promulgated under the Act.

F3 · derivative.exercise_date: On June 19, 2024, the Reporting Person was granted 1,371 RSUs under the Issuer's Amended & Restated 2013 Equity Incentive Plan, of which 1/4 of the RSUs vested on September 1, 2024, with the remaining RSUs vesting equally on a quarterly basis thereafter, subject to continued service on the Issuer's board of directors on the applicable vesting date.

F3 · derivative.expiration_date: On June 19, 2024, the Reporting Person was granted 1,371 RSUs under the Issuer's Amended & Restated 2013 Equity Incentive Plan, of which 1/4 of the RSUs vested on September 1, 2024, with the remaining RSUs vesting equally on a quarterly basis thereafter, subject to continued service on the Issuer's board of directors on the applicable vesting date.

SEC source: 0001628280-25-028918 · wk-form4_1748908890.xml · nonDerivative · entry 1

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,103

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction exempt from Section 16(b) of the Securities Exchange Act of 1934 (the "Act") pursuant to Rule 16b-6(b) promulgated under the Act.

SEC source: 0000059478-25-000150 · wk-form4_1747772589.xml · nonDerivative · entry 1

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,944.16

F1 · shares: At the election of the reporting person, the shares acquired pursuant to this filing have been deferred in lieu of cash compensation as stock units under the Lilly Directors' Deferral Plan and will be settled in shares of common stock following the reporting person's separation from service.

SEC source: 0000059478-25-000120 · wk-form4_1745353160.xml · nonDerivative · entry 1

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,931.027

F1 · shares: At the election of the reporting person, the shares acquired pursuant to this filing have been deferred in lieu of cash compensation as stock units under the Lilly Directors' Deferral Plan and will be settled in shares of common stock following the reporting person's separation from service.

SEC source: 0000059478-25-000099 · wk-form4_1742415842.xml · nonDerivative · entry 1

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,918.904

F1 · shares: At the election of the reporting person, the shares acquired pursuant to this filing have been deferred in lieu of cash compensation as stock units under the Lilly Directors' Deferral Plan and will be settled in shares of common stock following the reporting person's separation from service.

SEC source: 0001628280-25-009569 · wk-form4_1741047317.xml · derivative · entry 2

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 343

Underlying: Class A Common Stock · 342 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each Restricted Stock Unit ("RSU") represents a contingent right to receive one share of Class A Common Stock of the Issuer.

F1 · kind: Transaction exempt from Section 16(b) of the Securities Exchange Act of 1934 (the "Act") pursuant to Rule 16b-6(b) promulgated under the Act.

F3 · derivative.exercise_date: On June 19, 2024, the Reporting Person was granted 1,371 RSUs under the Issuer's Amended & Restated 2013 Equity Incentive Plan, of which 1/4 of the RSUs vested on September 1, 2024, with the remaining RSUs vesting equally on a quarterly basis thereafter, subject to continued service on the Issuer's board of directors on the applicable vesting date.

F3 · derivative.expiration_date: On June 19, 2024, the Reporting Person was granted 1,371 RSUs under the Issuer's Amended & Restated 2013 Equity Incentive Plan, of which 1/4 of the RSUs vested on September 1, 2024, with the remaining RSUs vesting equally on a quarterly basis thereafter, subject to continued service on the Issuer's board of directors on the applicable vesting date.

SEC source: 0001628280-25-009569 · wk-form4_1741047317.xml · nonDerivative · entry 1

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,760

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction exempt from Section 16(b) of the Securities Exchange Act of 1934 (the "Act") pursuant to Rule 16b-6(b) promulgated under the Act.

SEC source: 0000059478-25-000073 · wk-form4_1740000116.xml · nonDerivative · entry 1

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,903.892

F1 · shares: At the election of the reporting person, the shares acquired pursuant to this filing have been deferred in lieu of cash compensation as stock units under the Lilly Directors' Deferral Plan and will be settled in shares of common stock following the reporting person's separation from service.

SEC source: 0000059478-25-000012 · wk-form4_1737667361.xml · nonDerivative · entry 1

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,892.323

F1 · shares: At the election of the reporting person, the shares acquired pursuant to this filing have been deferred in lieu of cash compensation as stock units under the Lilly Directors' Deferral Plan and will be settled in shares of common stock following the reporting person's separation from service.

SEC source: 0000059478-24-000285 · wk-form4_1734470270.xml · nonDerivative · entry 1

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,878.965

F1 · shares: At the election of the reporting person, the shares acquired pursuant to this filing have been deferred in lieu of cash compensation as stock units under the Lilly Directors' Deferral Plan and will be settled in shares of common stock following the reporting person's separation from service.

SEC source: 0001628280-24-049603 · wk-form4_1733176902.xml · derivative · entry 2

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 685

Underlying: Class A Common Stock · 343 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each Restricted Stock Unit ("RSU") represents a contingent right to receive one share of Class A Common Stock of the Issuer.

F1 · kind: Transaction exempt from Section 16(b) of the Securities Exchange Act of 1934 (the "Act") pursuant to Rule 16b-6(b) promulgated under the Act.

F3 · derivative.exercise_date: On June 19, 2024, the Reporting Person was granted 1,371 RSUs under the Issuer's Amended & Restated 2013 Equity Incentive Plan, of which 1/4 of the RSUs vested on September 1, 2024, with the remaining RSUs vesting equally on a quarterly basis thereafter, subject to continued service on the Issuer's board of directors on the applicable vesting date.

F3 · derivative.expiration_date: On June 19, 2024, the Reporting Person was granted 1,371 RSUs under the Issuer's Amended & Restated 2013 Equity Incentive Plan, of which 1/4 of the RSUs vested on September 1, 2024, with the remaining RSUs vesting equally on a quarterly basis thereafter, subject to continued service on the Issuer's board of directors on the applicable vesting date.

SEC source: 0001628280-24-049603 · wk-form4_1733176902.xml · nonDerivative · entry 1

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,418

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction exempt from Section 16(b) of the Securities Exchange Act of 1934 (the "Act") pursuant to Rule 16b-6(b) promulgated under the Act.

SEC source: 0000059478-24-000266 · wk-form4_1732137825.xml · nonDerivative · entry 2

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,864.122

SEC source: 0000059478-24-000266 · wk-form4_1732137825.xml · nonDerivative · entry 1

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,561.592

F1 · shares: At the election of the reporting person, the shares acquired in this row have been deferred in lieu of cash compensation as stock units under the Lilly Directors' Deferral Plan and will be settled in shares of common stock following the reporting person's separation from service.

SEC source: 0000059478-24-000232 · wk-form4_1729628298.xml · nonDerivative · entry 1

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,548

F1 · shares: At the election of the reporting person, the shares acquired pursuant to this filing have been deferred in lieu of cash compensation as stock units under the Lilly Directors' Deferral Plan and will be settled in shares of common stock following the reporting person's separation from service.

SEC source: 0000059478-24-000219 · wk-form4_1726607497.xml · nonDerivative · entry 1

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,537

F1 · shares: At the election of the reporting person, the shares acquired pursuant to this filing have been deferred in lieu of cash compensation as stock units under the Lilly Directors' Deferral Plan and will be settled in shares of common stock following the reporting person's separation from service.

SEC source: 0001628280-24-039156 · wk-form4_1725397056.xml · derivative · entry 2

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,028

Underlying: Class A Common Stock · 343 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each Restricted Stock Unit ("RSU") represents a contingent right to receive one share of Class A Common Stock of the Issuer.

F1 · kind: Transaction exempt from Section 16(b) of the Securities Exchange Act of 1934 (the "Act") pursuant to Rule 16b-6(b) promulgated under the Act.

F3 · derivative.exercise_date: On June 19, 2024, the Reporting Person was granted 1,371 RSUs under the Issuer's Amended & Restated 2013 Equity Incentive Plan, of which 1/4 of the RSUs vested on September 1, 2024, with the remaining RSUs vesting equally on a quarterly basis thereafter, subject to continued service on the Issuer's board of directors on the applicable vesting date.

F3 · derivative.expiration_date: On June 19, 2024, the Reporting Person was granted 1,371 RSUs under the Issuer's Amended & Restated 2013 Equity Incentive Plan, of which 1/4 of the RSUs vested on September 1, 2024, with the remaining RSUs vesting equally on a quarterly basis thereafter, subject to continued service on the Issuer's board of directors on the applicable vesting date.

SEC source: 0001628280-24-039156 · wk-form4_1725397056.xml · nonDerivative · entry 1

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,075

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction exempt from Section 16(b) of the Securities Exchange Act of 1934 (the "Act") pursuant to Rule 16b-6(b) promulgated under the Act.

SEC source: 0000059478-24-000200 · wk-form4_1724184842.xml · nonDerivative · entry 1

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,524

F1 · shares: At the election of the reporting person, the shares acquired pursuant to this filing have been deferred in lieu of cash compensation as stock units under the Lilly Directors' Deferral Plan and will be settled in shares of common stock following the reporting person's separation from service.

SEC source: 0000059478-24-000168 · wk-form4_1721161124.xml · nonDerivative · entry 1

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,513

F1 · shares: At the election of the reporting person, the shares acquired pursuant to this filing have been deferred in lieu of cash compensation as stock units under the Lilly Directors' Deferral Plan and will be settled in shares of common stock following the reporting person's separation from service.

SEC source: 0001847903-24-000106 · wk-form4_1719520440.xml · derivative · entry 1

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 48,000

Underlying: Ordinary Shares · 48,000 shares

Expires 2034-06-25

F1 · derivative.exercise_date: The shares subject to such option will vest in full on the earlier of (i) the first anniversary of the grant date or (ii) the Issuer's next annual meeting of shareholders, subject to continued service as a director through the applicable vesting date.

F2 · derivative.underlying: The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents one Ordinary Share.

SEC source: 0001628280-24-029194 · wk-form4_1718926970.xml · derivative · entry 2

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,371

Underlying: Class A Common Stock · 1,371 shares

Expires not disclosed

F1 · derivative.exercise_price: Each Restricted Stock Unit ("RSU") represents a contingent right to receive one share of Class A Common Stock of the Issuer.

F2 · derivative.exercise_date: The RSUs were granted under the Issuer's Amended & Restated 2013 Equity Incentive Plan. The Reporting Person vests ownership in the RSUs over one year with 1/4 of the RSUs vesting on September 1, 2024, and 1/4 of the RSUs vesting on a quarterly basis thereafter, subject to continued service to the Issuer by the Reporting Person.

F2 · derivative.expiration_date: The RSUs were granted under the Issuer's Amended & Restated 2013 Equity Incentive Plan. The Reporting Person vests ownership in the RSUs over one year with 1/4 of the RSUs vesting on September 1, 2024, and 1/4 of the RSUs vesting on a quarterly basis thereafter, subject to continued service to the Issuer by the Reporting Person.

SEC source: 0000059478-24-000150 · wk-form4_1718741947.xml · nonDerivative · entry 1

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,503

F1 · shares: At the election of the reporting person, the shares acquired pursuant to this filing have been deferred in lieu of cash compensation as stock units under the Lilly Directors' Deferral Plan and will be settled in shares of common stock following the reporting person's separation from service.

SEC source: 0001628280-24-026410 · wk-form4_1717448969.xml · derivative · entry 2

Hedley Mary Lynne · CIK 0001340823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Class A Common Stock · 302 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each Restricted Stock Unit ("RSU") represents a contingent right to receive one share of Class A Common Stock of the Issuer.

F1 · kind: Transaction exempt from Section 16(b) of the Securities Exchange Act of 1934 (the "Act") pursuant to Rule 16b-6(b) promulgated under the Act.

F3 · derivative.exercise_date: On June 21, 2023, the Reporting Person was granted 1,209 RSUs under the Issuer's Amended & Restated 2013 Equity Incentive Plan, of which 1/4 of the RSUs vested on September 1, 2023, with the remaining RSUs vesting equally on a quarterly basis thereafter, subject to continued service on the Issuer's board of directors on the applicable vesting date.

F3 · derivative.expiration_date: On June 21, 2023, the Reporting Person was granted 1,209 RSUs under the Issuer's Amended & Restated 2013 Equity Incentive Plan, of which 1/4 of the RSUs vested on September 1, 2023, with the remaining RSUs vesting equally on a quarterly basis thereafter, subject to continued service on the Issuer's board of directors on the applicable vesting date.