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Dambkowski Carl

Disclosed activity across 2 companies

Tapewire entity
1942
SEC CIK
0001983476

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Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
Oruka Therapeutics, Inc.ORKA · Entity 3781DirectorJune 11, 2026June 12, 2026

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

Oruka Therapeutics, Inc.

Report date June 11, 2026 · Filed June 12, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect38,743 Ending reported balance After 2026-06-12 transaction · row 2
2 source rows · reconciled sequence

Row 1 · 2026-06-11 · Sale · Disposed 22,417 · Balance 51,326

F1: These sales were effected pursuant to a Rule 10b5-1 trading plan entered into on February 19, 2026.

F2: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $70.00 to $70.65, inclusive. The reporting person undertakes to provide to Oruka Therapeutics, Inc., any security holder of Oruka Therapeutics, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (2) and (3) to this Form 4.

Row 2 · 2026-06-12 · Sale · Disposed 12,583 · Balance 38,743

F1: These sales were effected pursuant to a Rule 10b5-1 trading plan entered into on February 19, 2026.

F3: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $70.00 to $70.50, inclusive.

Filing footnotes · ownership attribution and instrument terms

F1: These sales were effected pursuant to a Rule 10b5-1 trading plan entered into on February 19, 2026.

F2: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $70.00 to $70.65, inclusive. The reporting person undertakes to provide to Oruka Therapeutics, Inc., any security holder of Oruka Therapeutics, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (2) and (3) to this Form 4.

F3: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $70.00 to $70.50, inclusive.

Past disclosures · reporting ended (1)

No longer tracked through insider filings. These historical balances do not imply present ownership or a zero position.

Apogee Therapeutics, Inc.

Report date September 02, 2026 · Filed September 03, 2026

Section 16 reporting ended · disclosed 2026-09-03. Current position is not established by this disclosure.

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect0 Ending reported balance After 2026-09-03 transaction · row 2
2 source rows · reconciled sequence

Row 1 · 2026-09-02 · Disposition to issuer · Disposed 1,375 · Balance 167,123

Row 2 · 2026-09-03 · Disposition to issuer · Disposed 167,123 · Balance 0

F1: The reported securities represent shares of the Issuer's common stock disposed of pursuant to the terms of the Agreement and Plan of Merger, dated as of June 18, 2026 (the "Merger Agreement"), among Andor LLC, Andor Merger Co., the Issuer and AbbVie Inc.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $22.86 · Expires 2033-12-18Direct0 Reported balance After 2026-09-03 transaction · row 3 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 3 · 2026-09-03 · Disposition to issuer · Disposed 110,665 · Balance 0

F3: Each reported option was disposed of, pursuant to the Merger Agreement, in exchange for a cash payment equal to the excess of the per share merger consideration of $135.11 over the exercise price of such option.

F2: The reported options were vested as of the date of the Merger or became fully vested in connection with the Merger.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $49.07 · Expires 2034-12-09Direct0 Reported balance After 2026-09-03 transaction · row 4 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 4 · 2026-09-03 · Disposition to issuer · Disposed 124,962 · Balance 0

F3: Each reported option was disposed of, pursuant to the Merger Agreement, in exchange for a cash payment equal to the excess of the per share merger consideration of $135.11 over the exercise price of such option.

F2: The reported options were vested as of the date of the Merger or became fully vested in connection with the Merger.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $75.78 · Expires 2036-01-02Direct0 Reported balance After 2026-09-03 transaction · row 5 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 5 · 2026-09-03 · Disposition to issuer · Disposed 83,690 · Balance 0

F3: Each reported option was disposed of, pursuant to the Merger Agreement, in exchange for a cash payment equal to the excess of the per share merger consideration of $135.11 over the exercise price of such option.

F2: The reported options were vested as of the date of the Merger or became fully vested in connection with the Merger.

Filing footnotes · ownership attribution and instrument terms

F1: The reported securities represent shares of the Issuer's common stock disposed of pursuant to the terms of the Agreement and Plan of Merger, dated as of June 18, 2026 (the "Merger Agreement"), among Andor LLC, Andor Merger Co., the Issuer and AbbVie Inc.

F2: The reported options were vested as of the date of the Merger or became fully vested in connection with the Merger.

F3: Each reported option was disposed of, pursuant to the Merger Agreement, in exchange for a cash payment equal to the excess of the per share merger consideration of $135.11 over the exercise price of such option.

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
September 03, 2026 Filed Sep 3, 2026 20:39 UTC Apogee Therapeutics, Inc. APGE · Entity 1939 Disposition to issuerStock Option (Right to Buy) · Derivative 83,690 Not disclosed Strike: $75.78 Not disclosed
Disclosure

SEC source: 0001140361-26-035613 · form4.xml · derivative · entry 5

Dambkowski Carl · CIK 0001983476 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 83,690 shares

Expires 2036-01-02

F3 · price: Each reported option was disposed of, pursuant to the Merger Agreement, in exchange for a cash payment equal to the excess of the per share merger consideration of $135.11 over the exercise price of such option.

F2 · derivative.exercise_date: The reported options were vested as of the date of the Merger or became fully vested in connection with the Merger.

F3 · derivative.exercise_date: Each reported option was disposed of, pursuant to the Merger Agreement, in exchange for a cash payment equal to the excess of the per share merger consideration of $135.11 over the exercise price of such option.

Read SEC document
September 03, 2026 Filed Sep 3, 2026 20:39 UTC Apogee Therapeutics, Inc. APGE · Entity 1939 Disposition to issuerStock Option (Right to Buy) · Derivative 124,962 Not disclosed Strike: $49.07 Not disclosed
Disclosure

SEC source: 0001140361-26-035613 · form4.xml · derivative · entry 4

Dambkowski Carl · CIK 0001983476 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 124,962 shares

Expires 2034-12-09

F3 · price: Each reported option was disposed of, pursuant to the Merger Agreement, in exchange for a cash payment equal to the excess of the per share merger consideration of $135.11 over the exercise price of such option.

F2 · derivative.exercise_date: The reported options were vested as of the date of the Merger or became fully vested in connection with the Merger.

F3 · derivative.exercise_date: Each reported option was disposed of, pursuant to the Merger Agreement, in exchange for a cash payment equal to the excess of the per share merger consideration of $135.11 over the exercise price of such option.

Read SEC document
September 03, 2026 Filed Sep 3, 2026 20:39 UTC Apogee Therapeutics, Inc. APGE · Entity 1939 Disposition to issuerStock Option (Right to Buy) · Derivative 110,665 Not disclosed Strike: $22.86 Not disclosed
Disclosure

SEC source: 0001140361-26-035613 · form4.xml · derivative · entry 3

Dambkowski Carl · CIK 0001983476 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 110,665 shares

Expires 2033-12-18

F3 · price: Each reported option was disposed of, pursuant to the Merger Agreement, in exchange for a cash payment equal to the excess of the per share merger consideration of $135.11 over the exercise price of such option.

F2 · derivative.exercise_date: The reported options were vested as of the date of the Merger or became fully vested in connection with the Merger.

F3 · derivative.exercise_date: Each reported option was disposed of, pursuant to the Merger Agreement, in exchange for a cash payment equal to the excess of the per share merger consideration of $135.11 over the exercise price of such option.

Read SEC document
September 03, 2026 Filed Sep 3, 2026 20:39 UTC Apogee Therapeutics, Inc. APGE · Entity 1939 Disposition to issuerCommon Stock 167,123 Not disclosed Not disclosed
Disclosure

SEC source: 0001140361-26-035613 · form4.xml · nonDerivative · entry 2

Dambkowski Carl · CIK 0001983476 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

F1 · shares: The reported securities represent shares of the Issuer's common stock disposed of pursuant to the terms of the Agreement and Plan of Merger, dated as of June 18, 2026 (the "Merger Agreement"), among Andor LLC, Andor Merger Co., the Issuer and AbbVie Inc.

F1 · price: The reported securities represent shares of the Issuer's common stock disposed of pursuant to the terms of the Agreement and Plan of Merger, dated as of June 18, 2026 (the "Merger Agreement"), among Andor LLC, Andor Merger Co., the Issuer and AbbVie Inc.

Read SEC document
September 02, 2026 Filed Sep 3, 2026 20:39 UTC Apogee Therapeutics, Inc. APGE · Entity 1939 Disposition to issuerCommon Stock 1,375 $135.06 $185,707.50
Disclosure

SEC source: 0001140361-26-035613 · form4.xml · nonDerivative · entry 1

Dambkowski Carl · CIK 0001983476 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 167,123

Read SEC document
August 05, 2026 Filed Aug 8, 2026 00:00 UTC Apogee Therapeutics, Inc. APGE · Entity 1939 Exercise / conversionStock Option (Right to Buy) · Derivative 4,125 $0.00 Strike: $22.86 $0.00
Disclosure

SEC source: 0001104659-26-092838 · tm2622546-1_4seq1.xml · derivative · entry 3

Dambkowski Carl · CIK 0001983476 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 110,665

Underlying: Common Stock · 4,125 shares

Expires 2033-12-18

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: This option represents the right to purchase 175,345 shares of the Issuer's common stock, which will vest in forty-eight equal monthly installments through December 18, 2027, subject to the Reporting Person's continued service to the Issuer.

Read SEC document
August 05, 2026 Filed Aug 8, 2026 00:00 UTC Apogee Therapeutics, Inc. APGE · Entity 1939 SaleCommon Stock 5,500 $134.17 $737,935.00
Disclosure

SEC source: 0001104659-26-092838 · tm2622546-1_4seq1.xml · nonDerivative · entry 2

Dambkowski Carl · CIK 0001983476 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 168,498

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on September 22, 2025.

Read SEC document
August 05, 2026 Filed Aug 8, 2026 00:00 UTC Apogee Therapeutics, Inc. APGE · Entity 1939 Exercise / conversionCommon Stock 4,125 $22.86 $94,297.50
Disclosure

SEC source: 0001104659-26-092838 · tm2622546-1_4seq1.xml · nonDerivative · entry 1

Dambkowski Carl · CIK 0001983476 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 173,998

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
July 14, 2026 Filed Jul 17, 2026 00:00 UTC Apogee Therapeutics, Inc. APGE · Entity 1939 GiftCommon Stock 8,000 $0.00 $0.00
Disclosure

SEC source: 0001104659-26-084344 · tm2620587-1_4seq1.xml · nonDerivative · entry 1

Dambkowski Carl · CIK 0001983476 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 169,873

F1 · kind: This transaction involves a bona fide gift of securities from the reporting person to a donor advised fund.

Read SEC document
July 01, 2026 Filed Jul 3, 2026 00:13 UTC Apogee Therapeutics, Inc. APGE · Entity 1939 Exercise / conversionStock Option (Right to Buy) · Derivative 4,125 $0.00 Strike: $22.86 $0.00
Disclosure

SEC source: 0001104659-26-080477 · tm2619720-1_4seq1.xml · derivative · entry 3

Dambkowski Carl · CIK 0001983476 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 114,790

Underlying: Common Stock · 4,125 shares

Expires 2033-12-18

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: This option represents the right to purchase 175,345 shares of the Issuer's common stock, which will vest in forty-eight equal monthly installments through December 18, 2027, subject to the Reporting Person's continued service to the Issuer.

Read SEC document
July 01, 2026 Filed Jul 3, 2026 00:13 UTC Apogee Therapeutics, Inc. APGE · Entity 1939 SaleCommon Stock 5,500 $132.74 $730,070.00
Disclosure

SEC source: 0001104659-26-080477 · tm2619720-1_4seq1.xml · nonDerivative · entry 2

Dambkowski Carl · CIK 0001983476 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 177,873

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on September 22, 2025.

Read SEC document
July 01, 2026 Filed Jul 3, 2026 00:13 UTC Apogee Therapeutics, Inc. APGE · Entity 1939 Exercise / conversionCommon Stock 4,125 $22.86 $94,297.50
Disclosure

SEC source: 0001104659-26-080477 · tm2619720-1_4seq1.xml · nonDerivative · entry 1

Dambkowski Carl · CIK 0001983476 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 183,373

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 22, 2026 Filed Jun 25, 2026 00:01 UTC Apogee Therapeutics, Inc. APGE · Entity 1939 SaleCommon Stock 26,400 $132.60 $3,500,640.00
Disclosure

SEC source: 0001104659-26-077427 · tm2618514-1_4seq1.xml · nonDerivative · entry 1

Dambkowski Carl · CIK 0001983476 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 179,248

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on September 22, 2025.

F2 · price: The price reported above is a weighted average price. The shares were sold in multiple transactions at prices ranging from $132.550 to $132.645, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
June 12, 2026 Filed Jun 12, 2026 20:36 UTC Oruka Therapeutics, Inc. ORKA · Entity 3781 SaleCommon Stock 12,583 $70.11 $882,181.55
Disclosure

SEC source: 0000907654-26-000054 · form4.xml · nonDerivative · entry 2

Dambkowski Carl · CIK 0001983476 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 38,743

F1 · kind: These sales were effected pursuant to a Rule 10b5-1 trading plan entered into on February 19, 2026.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $70.00 to $70.50, inclusive.

Read SEC document
June 11, 2026 Filed Jun 12, 2026 20:36 UTC Oruka Therapeutics, Inc. ORKA · Entity 3781 SaleCommon Stock 22,417 $70.13 $1,572,200.60
Disclosure

SEC source: 0000907654-26-000054 · form4.xml · nonDerivative · entry 1

Dambkowski Carl · CIK 0001983476 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 51,326

F1 · kind: These sales were effected pursuant to a Rule 10b5-1 trading plan entered into on February 19, 2026.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $70.00 to $70.65, inclusive. The reporting person undertakes to provide to Oruka Therapeutics, Inc., any security holder of Oruka Therapeutics, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (2) and (3) to this Form 4.

Read SEC document
June 03, 2026 Filed Jun 6, 2026 00:00 UTC Apogee Therapeutics, Inc. APGE · Entity 1939 Exercise / conversionStock Option (Right to Buy) · Derivative 4,125 $0.00 Strike: $22.86 $0.00
Disclosure

SEC source: 0001104659-26-071076 · tm2616980-1_4seq1.xml · derivative · entry 3

Dambkowski Carl · CIK 0001983476 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 118,915

Underlying: Common Stock · 4,125 shares

Expires 2033-12-18

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: This option represents the right to purchase 175,345 shares of the Issuer's common stock, which will vest in forty-eight equal monthly installments through December 18, 2027, subject to the Reporting Person's continued service to the Issuer.

Read SEC document
June 03, 2026 Filed Jun 6, 2026 00:00 UTC Apogee Therapeutics, Inc. APGE · Entity 1939 SaleCommon Stock 5,500 $78.71 $432,905.00
Disclosure

SEC source: 0001104659-26-071076 · tm2616980-1_4seq1.xml · nonDerivative · entry 2

Dambkowski Carl · CIK 0001983476 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 205,648

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on September 22, 2025.

Read SEC document
June 03, 2026 Filed Jun 6, 2026 00:00 UTC Apogee Therapeutics, Inc. APGE · Entity 1939 Exercise / conversionCommon Stock 4,125 $22.86 $94,297.50
Disclosure

SEC source: 0001104659-26-071076 · tm2616980-1_4seq1.xml · nonDerivative · entry 1

Dambkowski Carl · CIK 0001983476 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 211,148

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 02, 2026 Filed Jun 3, 2026 20:52 UTC Oruka Therapeutics, Inc. ORKA · Entity 3781 GrantStock Option (right to buy) · Derivative 9,136 $0.00 Strike: $55.23 $0.00
Disclosure

SEC source: 0000907654-26-000052 · form4.xml · derivative · entry 1

Dambkowski Carl · CIK 0001983476 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,136

Underlying: Common Stock · 9,136 shares

Expires 2036-06-01

F1 · derivative.exercise_date: The option vests as to 1/12 of the underlying shares monthly from June 2, 2026.

Read SEC document
May 21, 2026 Filed May 22, 2026 20:54 UTC Oruka Therapeutics, Inc. ORKA · Entity 3781 Exercise / conversionStock Option (right to buy) · Derivative 11,667 $0.00 Strike: $11.77 $0.00
Disclosure

SEC source: 0000907654-26-000043 · form4.xml · derivative · entry 9

Dambkowski Carl · CIK 0001983476 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 5,833

Underlying: Common Stock · 11,667 shares

Expires 2035-06-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_date: The option vests as to 1/12 of the shares underlying the option monthly from June 2, 2025.

Read SEC document
May 21, 2026 Filed May 22, 2026 20:54 UTC Oruka Therapeutics, Inc. ORKA · Entity 3781 Exercise / conversionWarrant (right to buy) · Derivative 11,904 $0.00 Strike: $7.80 $0.00
Disclosure

SEC source: 0000907654-26-000043 · form4.xml · derivative · entry 8

Dambkowski Carl · CIK 0001983476 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 10,952

Underlying: Common Stock · 11,904 shares

Expires 2034-07-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: The option vests as to 25% of the shares underlying the option on April 3, 2025, and as to 1/48 of the shares underlying the option monthly thereafter.

Read SEC document
May 21, 2026 Filed May 22, 2026 20:54 UTC Oruka Therapeutics, Inc. ORKA · Entity 3781 Exercise / conversionStock Option (right to buy) · Derivative 38,689 $0.00 Strike: $6.84 $0.00
Disclosure

SEC source: 0000907654-26-000043 · form4.xml · derivative · entry 7

Dambkowski Carl · CIK 0001983476 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 32,737

Underlying: Common Stock · 38,689 shares

Expires 2034-05-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The option vests as to 25% of the shares underlying the option on March 1, 2025, and as to 1/48 of the shares underlying the option monthly thereafter.

Read SEC document
May 21, 2026 Filed May 22, 2026 20:54 UTC Oruka Therapeutics, Inc. ORKA · Entity 3781 SaleCommon Stock 13,235 $59.97 $793,661.92
Disclosure

SEC source: 0000907654-26-000043 · form4.xml · nonDerivative · entry 6

Dambkowski Carl · CIK 0001983476 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 73,743

F1 · kind: These sales were effected pursuant to a Rule 10b5-1 trading plan entered into on February 19, 2026.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $59.71 to $60.31, inclusive.

Read SEC document
May 21, 2026 Filed May 22, 2026 20:54 UTC Oruka Therapeutics, Inc. ORKA · Entity 3781 SaleCommon Stock 53,447 $59.10 $3,158,910.11
Disclosure

SEC source: 0000907654-26-000043 · form4.xml · nonDerivative · entry 5

Dambkowski Carl · CIK 0001983476 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 86,978

F1 · kind: These sales were effected pursuant to a Rule 10b5-1 trading plan entered into on February 19, 2026.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $58.71 to $59.70, inclusive.

Read SEC document
May 21, 2026 Filed May 22, 2026 20:54 UTC Oruka Therapeutics, Inc. ORKA · Entity 3781 SaleCommon Stock 38,318 $58.43 $2,238,794.29
Disclosure

SEC source: 0000907654-26-000043 · form4.xml · nonDerivative · entry 4

Dambkowski Carl · CIK 0001983476 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 140,425

F1 · kind: These sales were effected pursuant to a Rule 10b5-1 trading plan entered into on February 19, 2026.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $57.71 to $58.70, inclusive. The reporting person undertakes to provide to Oruka Therapeutics, Inc., any security holder of Oruka Therapeutics, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (2), (3) and (4) to this Form 4.

Read SEC document
May 21, 2026 Filed May 22, 2026 20:54 UTC Oruka Therapeutics, Inc. ORKA · Entity 3781 Exercise / conversionCommon Stock 11,667 $11.77 $137,320.59
Disclosure

SEC source: 0000907654-26-000043 · form4.xml · nonDerivative · entry 3

Dambkowski Carl · CIK 0001983476 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 178,743

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 21, 2026 Filed May 22, 2026 20:54 UTC Oruka Therapeutics, Inc. ORKA · Entity 3781 Exercise / conversionCommon Stock 11,904 $7.80 $92,851.20
Disclosure

SEC source: 0000907654-26-000043 · form4.xml · nonDerivative · entry 2

Dambkowski Carl · CIK 0001983476 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 167,076

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 21, 2026 Filed May 22, 2026 20:54 UTC Oruka Therapeutics, Inc. ORKA · Entity 3781 Exercise / conversionCommon Stock 38,689 $6.84 $264,632.76
Disclosure

SEC source: 0000907654-26-000043 · form4.xml · nonDerivative · entry 1

Dambkowski Carl · CIK 0001983476 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 155,172

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 06, 2026 Filed May 9, 2026 00:00 UTC Apogee Therapeutics, Inc. APGE · Entity 1939 Exercise / conversionStock Option (Right to Buy) · Derivative 4,125 $0.00 Strike: $22.86 $0.00
Disclosure

SEC source: 0001104659-26-058129 · tm2613976-1_4seq1.xml · derivative · entry 4

Dambkowski Carl · CIK 0001983476 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 123,040

Underlying: Common Stock · 4,125 shares

Expires 2033-12-18

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: This option represents the right to purchase 175,345 shares of the Issuer's common stock, which will vest in forty-eight equal monthly installments through December 18, 2027, subject to the Reporting Person's continued service to the Issuer.

Read SEC document
May 06, 2026 Filed May 9, 2026 00:00 UTC Apogee Therapeutics, Inc. APGE · Entity 1939 SaleCommon Stock 1,800 $84.60 $152,280.00
Disclosure

SEC source: 0001104659-26-058129 · tm2613976-1_4seq1.xml · nonDerivative · entry 3

Dambkowski Carl · CIK 0001983476 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 207,023

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on September 22, 2025.

F3 · price: The price reported above is a weighted average price. The shares were sold in multiple transactions at prices ranging from $84.44 to $84.69, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the SEC, upon request, full information regarding the number of shares sold at each separate price within the range.

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May 06, 2026 Filed May 9, 2026 00:00 UTC Apogee Therapeutics, Inc. APGE · Entity 1939 SaleCommon Stock 3,700 $83.92 $310,504.00
Disclosure

SEC source: 0001104659-26-058129 · tm2613976-1_4seq1.xml · nonDerivative · entry 2

Dambkowski Carl · CIK 0001983476 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 208,823

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on September 22, 2025.

F2 · price: The price reported above is a weighted average price. The shares were sold in multiple transactions at prices ranging from $83.35 to $84.28, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission ("SEC"), upon request, full information regarding the number of shares sold at each separate price within the range.

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May 06, 2026 Filed May 9, 2026 00:00 UTC Apogee Therapeutics, Inc. APGE · Entity 1939 Exercise / conversionCommon Stock 4,125 $22.86 $94,297.50
Disclosure

SEC source: 0001104659-26-058129 · tm2613976-1_4seq1.xml · nonDerivative · entry 1

Dambkowski Carl · CIK 0001983476 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 212,523

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

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April 01, 2026 Filed Apr 4, 2026 00:00 UTC Apogee Therapeutics, Inc. APGE · Entity 1939 Exercise / conversionStock Option (Right to Buy) · Derivative 4,125 $0.00 Strike: $22.86 $0.00
Disclosure

SEC source: 0001104659-26-039709 · tm2611042-1_4seq1.xml · derivative · entry 5

Dambkowski Carl · CIK 0001983476 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 127,165

Underlying: Common Stock · 4,125 shares

Expires 2033-12-18

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: This option represents the right to purchase 175,345 shares of the Issuer's common stock, which will vest in forty-eight equal monthly installments through December 18, 2027, subject to the Reporting Person's continued service to the Issuer.

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April 01, 2026 Filed Apr 4, 2026 00:00 UTC Apogee Therapeutics, Inc. APGE · Entity 1939 SaleCommon Stock 100 $85.89 $8,589.00
Disclosure

SEC source: 0001104659-26-039709 · tm2611042-1_4seq1.xml · nonDerivative · entry 4

Dambkowski Carl · CIK 0001983476 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 208,398

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on September 22, 2025.

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April 01, 2026 Filed Apr 4, 2026 00:00 UTC Apogee Therapeutics, Inc. APGE · Entity 1939 SaleCommon Stock 2,702 $85.33 $230,561.66
Disclosure

SEC source: 0001104659-26-039709 · tm2611042-1_4seq1.xml · nonDerivative · entry 3

Dambkowski Carl · CIK 0001983476 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 208,498

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on September 22, 2025.

F3 · price: The price reported above is a weighted average price. The shares were sold in multiple transactions at prices ranging from $84.87 to $85.80, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the SEC, upon request, full information regarding the number of shares sold at each separate price within the range.

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April 01, 2026 Filed Apr 4, 2026 00:00 UTC Apogee Therapeutics, Inc. APGE · Entity 1939 SaleCommon Stock 2,698 $84.31 $227,468.38
Disclosure

SEC source: 0001104659-26-039709 · tm2611042-1_4seq1.xml · nonDerivative · entry 2

Dambkowski Carl · CIK 0001983476 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 211,200

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on September 22, 2025.

F2 · price: The price reported above is a weighted average price. The shares were sold in multiple transactions at prices ranging from $83.87 to $84.84, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission ("SEC"), upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
April 01, 2026 Filed Apr 4, 2026 00:00 UTC Apogee Therapeutics, Inc. APGE · Entity 1939 Exercise / conversionCommon Stock 4,125 $22.86 $94,297.50
Disclosure

SEC source: 0001104659-26-039709 · tm2611042-1_4seq1.xml · nonDerivative · entry 1

Dambkowski Carl · CIK 0001983476 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 213,898

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
March 04, 2026 Filed Mar 7, 2026 01:00 UTC Apogee Therapeutics, Inc. APGE · Entity 1939 Exercise / conversionStock Option (Right to Buy) · Derivative 4,125 $0.00 Strike: $22.86 $0.00
Disclosure

SEC source: 0001104659-26-024831 · tm268128-1_4seq1.xml · derivative · entry 5

Dambkowski Carl · CIK 0001983476 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 131,290

Underlying: Common Stock · 4,125 shares

Expires 2033-12-18

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: This option represents the right to purchase 175,345 shares of the Issuer's common stock, which will vest in forty-eight equal monthly installments through December 18, 2027, subject to the Reporting Person's continued service to the Issuer.

Read SEC document
March 04, 2026 Filed Mar 7, 2026 01:00 UTC Apogee Therapeutics, Inc. APGE · Entity 1939 SaleCommon Stock 200 $73.26 $14,652.00
Disclosure

SEC source: 0001104659-26-024831 · tm268128-1_4seq1.xml · nonDerivative · entry 4

Dambkowski Carl · CIK 0001983476 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 209,773

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on September 22, 2025.

F4 · price: The price reported above is a weighted average price. The shares were sold in multiple transactions at prices ranging from $73.20 to $73.31, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the SEC, upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
March 04, 2026 Filed Mar 7, 2026 01:00 UTC Apogee Therapeutics, Inc. APGE · Entity 1939 SaleCommon Stock 2,075 $71.98 $149,358.50
Disclosure

SEC source: 0001104659-26-024831 · tm268128-1_4seq1.xml · nonDerivative · entry 3

Dambkowski Carl · CIK 0001983476 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 209,973

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on September 22, 2025.

F3 · price: The price reported above is a weighted average price. The shares were sold in multiple transactions at prices ranging from $71.51 to $72.45, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the SEC, upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
March 04, 2026 Filed Mar 7, 2026 01:00 UTC Apogee Therapeutics, Inc. APGE · Entity 1939 SaleCommon Stock 3,225 $70.33 $226,814.25
Disclosure

SEC source: 0001104659-26-024831 · tm268128-1_4seq1.xml · nonDerivative · entry 2

Dambkowski Carl · CIK 0001983476 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 212,048

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on September 22, 2025.

F2 · price: The price reported above is a weighted average price. The shares were sold in multiple transactions at prices ranging from $70.30 to $70.82, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission ("SEC"), upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
March 04, 2026 Filed Mar 7, 2026 01:00 UTC Apogee Therapeutics, Inc. APGE · Entity 1939 Exercise / conversionCommon Stock 4,125 $22.86 $94,297.50
Disclosure

SEC source: 0001104659-26-024831 · tm268128-1_4seq1.xml · nonDerivative · entry 1

Dambkowski Carl · CIK 0001983476 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 215,273

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 04, 2026 Filed Feb 5, 2026 01:02 UTC Apogee Therapeutics, Inc. APGE · Entity 1939 Exercise / conversionStock Option (Right to Buy) · Derivative 4,125 $0.00 Strike: $22.86 $0.00
Disclosure

SEC source: 0001104659-26-010454 · tm265045-2_4seq1.xml · derivative · entry 7

Dambkowski Carl · CIK 0001983476 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 135,415

Underlying: Common Stock · 4,125 shares

Expires 2033-12-18

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_date: This option represents the right to purchase 175,345 shares of the Issuer's common stock, which will vest in forty-eight equal monthly installments through December 18, 2027, subject to the Reporting Person's continued service to the Issuer.

Read SEC document
February 04, 2026 Filed Feb 5, 2026 01:02 UTC Apogee Therapeutics, Inc. APGE · Entity 1939 SaleCommon Stock 200 $68.94 $13,788.00
Disclosure

SEC source: 0001104659-26-010454 · tm265045-2_4seq1.xml · nonDerivative · entry 6

Dambkowski Carl · CIK 0001983476 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 211,148

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on September 22, 2025.

F6 · price: The price reported above is a weighted average price. The shares were sold in multiple transactions at prices ranging from $68.90 to $68.98, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the SEC, upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
February 04, 2026 Filed Feb 5, 2026 01:02 UTC Apogee Therapeutics, Inc. APGE · Entity 1939 SaleCommon Stock 100 $67.88 $6,788.00
Disclosure

SEC source: 0001104659-26-010454 · tm265045-2_4seq1.xml · nonDerivative · entry 5

Dambkowski Carl · CIK 0001983476 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 211,348

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on September 22, 2025.

F5 · price: The price reported above is a weighted average price. The shares were sold in multiple transactions at prices ranging from $67.80 to $67.95, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the SEC, upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
February 04, 2026 Filed Feb 5, 2026 01:02 UTC Apogee Therapeutics, Inc. APGE · Entity 1939 SaleCommon Stock 1,299 $66.85 $86,838.15
Disclosure

SEC source: 0001104659-26-010454 · tm265045-2_4seq1.xml · nonDerivative · entry 4

Dambkowski Carl · CIK 0001983476 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 211,448

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on September 22, 2025.

F4 · price: The price reported above is a weighted average price. The shares were sold in multiple transactions at prices ranging from $66.37 to $67.24, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the SEC, upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
February 04, 2026 Filed Feb 5, 2026 01:02 UTC Apogee Therapeutics, Inc. APGE · Entity 1939 SaleCommon Stock 1,420 $65.83 $93,478.60
Disclosure

SEC source: 0001104659-26-010454 · tm265045-2_4seq1.xml · nonDerivative · entry 3

Dambkowski Carl · CIK 0001983476 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 212,747

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on September 22, 2025.

F3 · price: The price reported above is a weighted average price. The shares were sold in multiple transactions at prices ranging from $65.27 to $66.25, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the SEC, upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
February 04, 2026 Filed Feb 5, 2026 01:02 UTC Apogee Therapeutics, Inc. APGE · Entity 1939 SaleCommon Stock 2,481 $64.88 $160,967.28
Disclosure

SEC source: 0001104659-26-010454 · tm265045-2_4seq1.xml · nonDerivative · entry 2

Dambkowski Carl · CIK 0001983476 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 214,167

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on September 22, 2025.

F2 · price: The price reported above is a weighted average price. The shares were sold in multiple transactions at prices ranging from $64.24 to $65.22, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission ("SEC"), upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
February 04, 2026 Filed Feb 5, 2026 01:02 UTC Apogee Therapeutics, Inc. APGE · Entity 1939 Exercise / conversionCommon Stock 4,125 $22.86 $94,297.50
Disclosure

SEC source: 0001104659-26-010454 · tm265045-2_4seq1.xml · nonDerivative · entry 1

Dambkowski Carl · CIK 0001983476 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 216,648

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 23, 2026 Filed Jan 23, 2026 21:31 UTC Oruka Therapeutics, Inc. ORKA · Entity 3781 OtherCommon Stock 116,483 $0.00 $0.00
Disclosure

SEC source: 0000907654-26-000013 · form4.xml · nonDerivative · entry 1

Dambkowski Carl · CIK 0001983476 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 116,483

F1 · kind: Represents the pro-rata distribution of shares of common stock for no consideration from a limited liability company in which the Reporting Person is a member.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.