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Xu Zhenyu

Disclosed activity across 1 company

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18449
SEC CIK
0002006362

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Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
SOPHiA GENETICS SASOPH · Entity 5228Chief Scientific OfficerOctober 13, 2026October 14, 2026

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

SOPHiA GENETICS SA

Report date October 13, 2026 · Filed October 14, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Ordinary SharesSEC Table I · non-derivativeDirect541,493 Reported balance After 2026-10-13 transaction · row 1
1 source row

Row 1 · 2026-10-13 · Sale · Disposed 4,000 · Balance 541,493

F1: Transaction made pursuant to duly adopted trading plan under Rule 10b5-1(c).

F2: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $7.09 to $7.24, inclusive. The Reporting Person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Filing footnotes · ownership attribution and instrument terms

F1: Transaction made pursuant to duly adopted trading plan under Rule 10b5-1(c).

F2: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $7.09 to $7.24, inclusive. The Reporting Person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
October 13, 2026 Filed Oct 14, 2026 20:03 UTC SOPHiA GENETICS SA SOPH · Entity 5228 SaleOrdinary Shares 4,000 $7.18 $28,727.20
Disclosure

SEC source: 0001840706-26-000343 · wk-form4_1792008234.xml · nonDerivative · entry 1

Xu Zhenyu · CIK 0002006362 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 541,493

F1 · shares: Transaction made pursuant to duly adopted trading plan under Rule 10b5-1(c).

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $7.09 to $7.24, inclusive. The Reporting Person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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October 05, 2026 Filed Oct 7, 2026 20:04 UTC SOPHiA GENETICS SA SOPH · Entity 5228 SaleOrdinary Shares 7,394 $8.12 $60,074.77
Disclosure

SEC source: 0001840706-26-000329 · wk-form4_1791403440.xml · nonDerivative · entry 1

Xu Zhenyu · CIK 0002006362 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 545,493

F1 · shares: Represents shares sold by the Reporting Person in the open market to satisfy tax withholding obligations arising in connection with the vesting of restricted stock units on October 2 and 3, 2026. These sales were effected pursuant to a pre-established Rule 10b5-1(c) trading plan adopted by the Reporting Person and do not represent discretionary trades.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $7.99 to $8.30, inclusive. The Reporting Person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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September 14, 2026 Filed Sep 16, 2026 20:01 UTC SOPHiA GENETICS SA SOPH · Entity 5228 SaleOrdinary Shares 4,000 $7.88 $31,537.60
Disclosure

SEC source: 0001840706-26-000313 · wk-form4_1789588876.xml · nonDerivative · entry 1

Xu Zhenyu · CIK 0002006362 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 552,887

F1 · shares: Transaction made pursuant to duly adopted trading plan under Rule 10b5-1(c).

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $7.78 to $7.99, inclusive. The Reporting Person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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August 27, 2026 Filed Aug 31, 2026 20:02 UTC SOPHiA GENETICS SA SOPH · Entity 5228 SaleOrdinary Shares 10,000 $8.91 $89,096.00
Disclosure

SEC source: 0001840706-26-000304 · wk-form4_1788206534.xml · nonDerivative · entry 1

Xu Zhenyu · CIK 0002006362 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 556,887

F1 · shares: Transaction made pursuant to duly adopted trading plan under Rule 10b5-1(c).

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $8.90 to $8.92, inclusive. The Reporting Person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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August 21, 2026 Filed Aug 21, 2026 20:01 UTC SOPHiA GENETICS SA SOPH · Entity 5228 SaleOrdinary Shares 5,408 $8.40 $45,446.67
Disclosure

SEC source: 0001840706-26-000292 · wk-form4_1787342516.xml · nonDerivative · entry 3

Xu Zhenyu · CIK 0002006362 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 566,887

F1 · shares: Transaction made pursuant to duly adopted trading plan under Rule 10b5-1(c).

F4 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $8.40 to $8.42, inclusive. The Reporting Person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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August 20, 2026 Filed Aug 21, 2026 20:01 UTC SOPHiA GENETICS SA SOPH · Entity 5228 SaleOrdinary Shares 4,592 $8.41 $38,608.62
Disclosure

SEC source: 0001840706-26-000292 · wk-form4_1787342516.xml · nonDerivative · entry 2

Xu Zhenyu · CIK 0002006362 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 572,295

F1 · shares: Transaction made pursuant to duly adopted trading plan under Rule 10b5-1(c).

F3 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $8.40 to $8.43, inclusive. The Reporting Person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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August 19, 2026 Filed Aug 21, 2026 20:01 UTC SOPHiA GENETICS SA SOPH · Entity 5228 SaleOrdinary Shares 10,000 $7.94 $79,427.00
Disclosure

SEC source: 0001840706-26-000292 · wk-form4_1787342516.xml · nonDerivative · entry 1

Xu Zhenyu · CIK 0002006362 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 576,887

F1 · shares: Transaction made pursuant to duly adopted trading plan under Rule 10b5-1(c).

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $7.90 to $8.01, inclusive. The Reporting Person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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August 13, 2026 Filed Aug 14, 2026 20:40 UTC SOPHiA GENETICS SA SOPH · Entity 5228 SaleOrdinary Shares 4,000 $7.52 $30,076.40
Disclosure

SEC source: 0001840706-26-000282 · wk-form4_1786740012.xml · nonDerivative · entry 1

Xu Zhenyu · CIK 0002006362 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 586,887

F1 · shares: Transaction made pursuant to duly adopted trading plan under Rule 10b5-1(c).

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $7.43 to $7.62, inclusive. The Reporting Person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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August 07, 2026 Filed Aug 7, 2026 21:35 UTC SOPHiA GENETICS SA SOPH · Entity 5228 Exercise / conversionShare Option (Right to Buy) · Derivative 7,000 $3.28 Strike: $3.28 $22,960.00
Disclosure

SEC source: 0001840706-26-000275 · wk-form4_1786138524.xml · derivative · entry 7

Xu Zhenyu · CIK 0002006362 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Ordinary Shares · 7,000 shares

Expires 2027-09-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: The share options are fully vested and exercisable.

F6 · balance_after: Following the transaction reported on this line, the Reporting Person holds an aggregate total of 975,041 derivative share options across all remaining grant tranches with varying exercise prices.

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August 07, 2026 Filed Aug 7, 2026 21:35 UTC SOPHiA GENETICS SA SOPH · Entity 5228 SaleOrdinary Shares 10,000 $7.48 $74,759.00
Disclosure

SEC source: 0001840706-26-000275 · wk-form4_1786138524.xml · nonDerivative · entry 5

Xu Zhenyu · CIK 0002006362 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 590,887

F1 · shares: Transaction made pursuant to duly adopted trading plan under Rule 10b5-1(c).

F3 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $7.40 to $7.56, inclusive. The Reporting Person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
August 07, 2026 Filed Aug 7, 2026 21:35 UTC SOPHiA GENETICS SA SOPH · Entity 5228 SaleOrdinary Shares 7,000 $7.02 $49,151.90
Disclosure

SEC source: 0001840706-26-000275 · wk-form4_1786138524.xml · nonDerivative · entry 4

Xu Zhenyu · CIK 0002006362 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 600,887

F1 · shares: Transaction made pursuant to duly adopted trading plan under Rule 10b5-1(c).

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $7.00 to $7.08, inclusive. The Reporting Person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
August 07, 2026 Filed Aug 7, 2026 21:35 UTC SOPHiA GENETICS SA SOPH · Entity 5228 Exercise / conversionOrdinary Shares 7,000 $3.28 $22,960.00
Disclosure

SEC source: 0001840706-26-000275 · wk-form4_1786138524.xml · nonDerivative · entry 3

Xu Zhenyu · CIK 0002006362 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 607,887

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: Transaction made pursuant to duly adopted trading plan under Rule 10b5-1(c).

Read SEC document
August 05, 2026 Filed Aug 7, 2026 21:35 UTC SOPHiA GENETICS SA SOPH · Entity 5228 Exercise / conversionShare Option (Right to Buy) · Derivative 3,000 $3.28 Strike: $3.28 $9,840.00
Disclosure

SEC source: 0001840706-26-000275 · wk-form4_1786138524.xml · derivative · entry 6

Xu Zhenyu · CIK 0002006362 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 7,000

Underlying: Ordinary Shares · 3,000 shares

Expires 2027-09-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: Transaction made pursuant to duly adopted trading plan under Rule 10b5-1(c).

F4 · derivative.exercise_date: The share options are fully vested and exercisable.

F5 · balance_after: Following the transaction reported on this line, the Reporting Person holds an aggregate total of 982,041 derivative share options across all remaining grant tranches with varying exercise prices.

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August 05, 2026 Filed Aug 7, 2026 21:35 UTC SOPHiA GENETICS SA SOPH · Entity 5228 SaleOrdinary Shares 3,000 $7.00 $21,012.90
Disclosure

SEC source: 0001840706-26-000275 · wk-form4_1786138524.xml · nonDerivative · entry 2

Xu Zhenyu · CIK 0002006362 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 600,887

F1 · shares: Transaction made pursuant to duly adopted trading plan under Rule 10b5-1(c).

Read SEC document
August 05, 2026 Filed Aug 7, 2026 21:35 UTC SOPHiA GENETICS SA SOPH · Entity 5228 Exercise / conversionOrdinary Shares 3,000 $3.28 $9,840.00
Disclosure

SEC source: 0001840706-26-000275 · wk-form4_1786138524.xml · nonDerivative · entry 1

Xu Zhenyu · CIK 0002006362 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 603,887

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: Transaction made pursuant to duly adopted trading plan under Rule 10b5-1(c).

Read SEC document
August 04, 2026 Filed Aug 5, 2026 20:13 UTC SOPHiA GENETICS SA SOPH · Entity 5228 SaleOrdinary Shares 10,000 $6.92 $69,168.00
Disclosure

SEC source: 0001840706-26-000269 · wk-form4_1785960834.xml · nonDerivative · entry 1

Xu Zhenyu · CIK 0002006362 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 600,887

F1 · shares: Transaction made pursuant to duly adopted trading plan under Rule 10b5-1(c).

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $6.90 to $6.95, inclusive. The Reporting Person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
July 13, 2026 Filed Jul 14, 2026 20:02 UTC SOPHiA GENETICS SA SOPH · Entity 5228 SaleOrdinary Shares 4,000 $5.70 $22,819.20
Disclosure

SEC source: 0001840706-26-000260 · wk-form4_1784059366.xml · nonDerivative · entry 1

Xu Zhenyu · CIK 0002006362 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 610,887

F1 · shares: Transaction made pursuant to duly adopted trading plan under Rule 10b5-1(c).

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $5.54 to $5.79, inclusive. The Reporting Person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
July 06, 2026 Filed Jul 7, 2026 20:03 UTC SOPHiA GENETICS SA SOPH · Entity 5228 SaleOrdinary Shares 7,393 $5.17 $38,241.77
Disclosure

SEC source: 0001840706-26-000250 · wk-form4_1783454623.xml · nonDerivative · entry 1

Xu Zhenyu · CIK 0002006362 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 614,887

F1 · shares: Represents shares sold by the Reporting Person in the open market to satisfy tax withholding obligations arising in connection with the vesting of restricted stock units on July 2 and July 3, 2026. These sales were effected pursuant to a pre-established Rule 10b5-1(c) trading plan adopted by the Reporting Person and do not represent discretionary trades.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $4.97 to $5.43, inclusive. The Reporting Person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
June 15, 2026 Filed Jun 17, 2026 20:02 UTC SOPHiA GENETICS SA SOPH · Entity 5228 SaleOrdinary Shares 4,000 $5.01 $20,056.40
Disclosure

SEC source: 0001840706-26-000211 · wk-form4_1781726561.xml · nonDerivative · entry 1

Xu Zhenyu · CIK 0002006362 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 622,280

F1 · shares: Transaction made pursuant to duly adopted trading plan under Rule 10b5-1(c).

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $4.90 to $5.13, inclusive. The Reporting Person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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May 19, 2026 Filed May 20, 2026 20:02 UTC SOPHiA GENETICS SA SOPH · Entity 5228 SaleOrdinary Shares 608 $4.60 $2,797.71
Disclosure

SEC source: 0001840706-26-000200 · wk-form4_1779307372.xml · nonDerivative · entry 1

Xu Zhenyu · CIK 0002006362 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 626,280

F1 · shares: Represents shares sold by the Reporting Person in the open market to satisfy tax withholding obligations arising in connection with the vesting of restricted stock units on May 18, 2026. These sales were effected pursuant to a pre-established Rule 10b5-1(c) trading plan adopted by the Reporting Person and do not represent discretionary trades.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $4.54 to $4.66, inclusive. The Reporting Person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
May 13, 2026 Filed May 14, 2026 20:01 UTC SOPHiA GENETICS SA SOPH · Entity 5228 SaleOrdinary Shares 4,000 $4.54 $18,168.40
Disclosure

SEC source: 0001840706-26-000186 · wk-form4_1778788910.xml · nonDerivative · entry 1

Xu Zhenyu · CIK 0002006362 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 626,888

F1 · shares: Transaction made pursuant to duly adopted trading plan under Rule 10b5-1(c).

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $4.48 to $4.65, inclusive. The Reporting Person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
April 20, 2026 Filed Apr 21, 2026 20:04 UTC SOPHiA GENETICS SA SOPH · Entity 5228 SaleOrdinary Shares 608 $5.21 $3,164.82
Disclosure

SEC source: 0001840706-26-000173 · wk-form4_1776801880.xml · nonDerivative · entry 1

Xu Zhenyu · CIK 0002006362 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 630,888

F1 · shares: Represents shares sold by the Reporting Person in the open market to satisfy tax withholding obligations arising in connection with the vesting of restricted stock units on April 18, 2026. These sales were effected pursuant to a pre-established Rule 10b5-1(c) trading plan adopted by the Reporting Person and do not represent discretionary trades.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $5.10 to $5.29, inclusive. The Reporting Person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
April 14, 2026 Filed Apr 16, 2026 20:03 UTC SOPHiA GENETICS SA SOPH · Entity 5228 SaleOrdinary Shares 600 $4.97 $2,979.78
Disclosure

SEC source: 0001840706-26-000160 · wk-form4_1776369817.xml · nonDerivative · entry 1

Xu Zhenyu · CIK 0002006362 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 631,496

F1 · shares: Transaction made pursuant to duly adopted trading plan under Rule 10b5-1(c).

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $4.82 to $5.16, inclusive. The Reporting Person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
April 13, 2026 Filed Apr 14, 2026 20:02 UTC SOPHiA GENETICS SA SOPH · Entity 5228 SaleOrdinary Shares 3,400 $4.76 $16,196.58
Disclosure

SEC source: 0001840706-26-000151 · wk-form4_1776196927.xml · nonDerivative · entry 3

Xu Zhenyu · CIK 0002006362 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 632,096

F4 · shares: Transaction made pursuant to duly adopted trading plan under Rule 10b5-1(c).

F3 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $4.63 to $4.88, inclusive. The Reporting Person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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April 13, 2026 Filed Apr 14, 2026 20:02 UTC SOPHiA GENETICS SA SOPH · Entity 5228 SaleOrdinary Shares 1,014 $4.76 $4,830.39
Disclosure

SEC source: 0001840706-26-000151 · wk-form4_1776196927.xml · nonDerivative · entry 2

Xu Zhenyu · CIK 0002006362 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 635,496

F1 · shares: Represents shares sold by the Reporting Person in the open market to satisfy tax withholding obligations arising in connection with the vesting of restricted stock units on April 2 and 3, 2026. These sales were effected pursuant to a pre-established Rule 10b5-1(c) trading plan adopted by the Reporting Person and do not represent discretionary trades.

F3 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $4.63 to $4.88, inclusive. The Reporting Person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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April 10, 2026 Filed Apr 14, 2026 20:02 UTC SOPHiA GENETICS SA SOPH · Entity 5228 SaleOrdinary Shares 3,706 $4.68 $17,347.04
Disclosure

SEC source: 0001840706-26-000151 · wk-form4_1776196927.xml · nonDerivative · entry 1

Xu Zhenyu · CIK 0002006362 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 636,510

F1 · shares: Represents shares sold by the Reporting Person in the open market to satisfy tax withholding obligations arising in connection with the vesting of restricted stock units on April 2 and 3, 2026. These sales were effected pursuant to a pre-established Rule 10b5-1(c) trading plan adopted by the Reporting Person and do not represent discretionary trades.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $4.61 to $4.77, inclusive. The Reporting Person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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April 09, 2026 Filed Apr 10, 2026 20:02 UTC SOPHiA GENETICS SA SOPH · Entity 5228 SaleOrdinary Shares 1,936 $4.74 $9,176.45
Disclosure

SEC source: 0001840706-26-000140 · wk-form4_1775851359.xml · nonDerivative · entry 2

Xu Zhenyu · CIK 0002006362 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 640,216

F1 · shares: Represents shares sold by the Reporting Person in the open market to satisfy tax withholding obligations arising in connection with the vesting of restricted stock units on April 2 and 3, 2026. These sales were effected pursuant to a pre-established Rule 10b5-1 trading plan adopted by the Reporting Person and do not represent discretionary trades.

F3 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $4.61 to $4.87, inclusive. The Reporting Person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
April 08, 2026 Filed Apr 10, 2026 20:02 UTC SOPHiA GENETICS SA SOPH · Entity 5228 SaleOrdinary Shares 2,800 $4.84 $13,549.20
Disclosure

SEC source: 0001840706-26-000140 · wk-form4_1775851359.xml · nonDerivative · entry 1

Xu Zhenyu · CIK 0002006362 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 642,152

F1 · shares: Represents shares sold by the Reporting Person in the open market to satisfy tax withholding obligations arising in connection with the vesting of restricted stock units on April 2 and 3, 2026. These sales were effected pursuant to a pre-established Rule 10b5-1 trading plan adopted by the Reporting Person and do not represent discretionary trades.

F2 · price: prices ranging from $4.79 to $4.92, inclusive. The Reporting Person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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April 07, 2026 Filed Apr 8, 2026 20:04 UTC SOPHiA GENETICS SA SOPH · Entity 5228 SaleOrdinary Shares 2,400 $4.87 $11,679.12
Disclosure

SEC source: 0001840706-26-000121 · wk-form4_1775678645.xml · nonDerivative · entry 2

Xu Zhenyu · CIK 0002006362 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 644,952

F1 · shares: Represents shares sold by the Reporting Person in the open market to satisfy tax withholding obligations arising in connection with the vesting of restricted stock units on April 2 and 3, 2026. These sales were effected pursuant to a pre-established Rule 10b5-1 trading plan adopted by the Reporting Person and do not represent discretionary trades.

F3 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $4.69 to $4.98, inclusive. The Reporting Person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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April 06, 2026 Filed Apr 8, 2026 20:04 UTC SOPHiA GENETICS SA SOPH · Entity 5228 SaleOrdinary Shares 2,700 $4.85 $13,100.40
Disclosure

SEC source: 0001840706-26-000121 · wk-form4_1775678645.xml · nonDerivative · entry 1

Xu Zhenyu · CIK 0002006362 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 647,352

F1 · shares: Represents shares sold by the Reporting Person in the open market to satisfy tax withholding obligations arising in connection with the vesting of restricted stock units on April 2 and 3, 2026. These sales were effected pursuant to a pre-established Rule 10b5-1 trading plan adopted by the Reporting Person and do not represent discretionary trades.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $4.67 to $4.95, inclusive. The Reporting Person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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April 02, 2026 Filed Apr 3, 2026 10:59 UTC SOPHiA GENETICS SA SOPH · Entity 5228 GrantShare Option (Right to Buy) · Derivative 164,671 $0.00 Strike: $5.04 $0.00
Disclosure

SEC source: 0001840706-26-000089 · wk-form4_1775213958.xml · derivative · entry 2

Xu Zhenyu · CIK 0002006362 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 164,671

Underlying: Ordinary Shares · 164,671 shares

Expires 2036-04-02

F2 · derivative.exercise_date: The share option vests and becomes exercisable as to 25% of the ordinary shares on April 2, 2027, and then in equal monthly installments through April 2, 2030.

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April 02, 2026 Filed Apr 3, 2026 10:59 UTC SOPHiA GENETICS SA SOPH · Entity 5228 GrantOrdinary Shares 112,936 $0.00 $0.00
Disclosure

SEC source: 0001840706-26-000089 · wk-form4_1775213958.xml · nonDerivative · entry 1

Xu Zhenyu · CIK 0002006362 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 112,936

F1 · shares: Represents a restricted stock unit ("RSU") grant made under the Issuer's 2021 Equity Incentive Plan. Each RSU represents a contingent right to receive one ordinary share of the Issuer, subject to the Reporting Person's continued service with the Issuer through each applicable vesting date. 25% of the RSUs will vest on April 2, 2027, and the remaining 75% will vest in equal quarterly installments through April 2, 2030.

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April 02, 2026 Filed Apr 8, 2026 12:46 UTC Amendment SOPHiA GENETICS SA SOPH · Entity 5228 GrantShare Option (Right to Buy) · Derivative 164,671 $0.00 Strike: $5.04 $0.00
Disclosure

SEC source: 0001840706-26-000103 · wk-form4a_1775652404.xml · derivative · entry 2

Xu Zhenyu · CIK 0002006362 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 164,671

Underlying: Ordinary Shares · 164,671 shares

Expires 2036-04-02

F3 · derivative.exercise_date: The share option vests and becomes exercisable as to 25% of the ordinary shares on April 2, 2027, and then in equal monthly installments through April 2, 2030.

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April 02, 2026 Filed Apr 8, 2026 12:46 UTC Amendment SOPHiA GENETICS SA SOPH · Entity 5228 GrantOrdinary Shares 112,936 $0.00 $0.00
Disclosure

SEC source: 0001840706-26-000103 · wk-form4a_1775652404.xml · nonDerivative · entry 1

Xu Zhenyu · CIK 0002006362 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 650,052

F1 · shares: Represents a restricted stock unit ("RSU") grant made under the Issuer's 2021 Equity Incentive Plan. Each RSU represents a contingent right to receive one ordinary share of the Issuer, subject to the Reporting Person's continued service with the Issuer. 25% of the RSUs will vest on April 2, 2027, and the remaining 75% will vest in equal quarterly installments through April 2, 2030.

F2 · balance_after: This Form 4/A amends the Form 4 filed on April 3, 2026 to correct the amount reported in Column 5 (Amount of Securities Beneficially Owned Following Reported Transaction), which was previously reported as 112,936 ordinary shares due to an inadvertent error. The correct amount is 650,052 ordinary shares.

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March 19, 2026 Filed Mar 20, 2026 20:01 UTC SOPHiA GENETICS SA SOPH · Entity 5228 SaleOrdinary Shares 608 $4.78 $2,907.03
Disclosure

SEC source: 0001840706-26-000068 · wk-form4_1774036883.xml · nonDerivative · entry 1

Xu Zhenyu · CIK 0002006362 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 537,116

F1 · shares: Represents shares sold by the Reporting Person in the open market to satisfy tax obligations arising in connection with the vesting of restricted stock units on March 18, 2026. These sales were effected pursuant to a pre-established Rule 10b5-1 trading plan adopted by the Reporting Person and do not represent discretionary trades.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $4.715 to $4.87, inclusive. The Reporting Person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.